The Carbonyl Is Part Of A -coo- Group Patents (Class 556/437)
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Patent number: 7232865Abstract: A method is provided for making siloxane polycarbonate copolymers and blends of other polycarbonates with such copolymers wherein the copolymers and blends have excellent transparency and physical characteristic.Type: GrantFiled: March 10, 2004Date of Patent: June 19, 2007Assignee: General Electric CompanyInventors: James Louis DeRudder, Niles Richard Rosenquist, Gary Charles Davis, Matthew Robert Pixton, Mark Erik Nelson, Zhaohui Su
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Patent number: 7232920Abstract: In one aspect, the invention provides a process for the preparation of compounds of Formula I wherein R1 is —CN, —OP, alkyl, aryl or heteroaryl; wherein P represents any suitable protecting group; and R2 is alkyl or aryl; by reacting a compound of Formula II wherein R1 is —CN, —OP, alkyl, aryl or heteroaryl; wherein P represents any suitable protecting group; and R2 is alkyl or aryl; with a reducing agent (e.g. sodium borohydride) in the presence of a metal halid (e.g. CeCl3) or a metal alkoxid (e.g. Ti(OiPr)4).Type: GrantFiled: April 22, 2003Date of Patent: June 19, 2007Assignee: BioconInventors: Tom Thomas Puthiaparampil, Acharya Poornaprajna, Chandrashekar Aswathanarayanappa, Madhavan Sridharan, Sambasivam Ganesh
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Patent number: 7217490Abstract: The invention includes new Si-containing monomers, polymers containing such monomers and photoresists that contain the polymers. Synthetic methods of the invention include reacting a vinyl carbocyclic aryl ester compound with a reactive silane compound to provide the monomer.Type: GrantFiled: March 3, 2003Date of Patent: May 15, 2007Assignee: Shipley Company, L.L.C.Inventors: George G. Barclay, Subbareddy Kanagasabapathy, Matthew A. King
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Patent number: 7169874Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: November 2, 2001Date of Patent: January 30, 2007Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7169949Abstract: Including a triazine UV light absorber having a silane group in a coating improves scratch and mar resistance after weathering.Type: GrantFiled: September 30, 2004Date of Patent: January 30, 2007Assignee: BASF CorporationInventors: John E. Boisseau, Swaminathan Ramesh
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Patent number: 7148369Abstract: The invention concerns organosilicon compounds, their method of preparation and their use as coupling agents for deposition, at the surface of a solid support, an organized self-assembled monolayer. The invention also concerns a method for obtaining solid supports whereof the surface is modified by an organized self-assembled monolayer comprising a system of said organosilicon compounds, and the use of said solid supports for biomolecular synthesis or immobilization.Type: GrantFiled: January 17, 2001Date of Patent: December 12, 2006Assignee: Centre National de la Recherche Scientifique (CNRS)Inventors: Bernard Benneteau, Jamal Bousbaa, Franck Choplin
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Patent number: 7138440Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: January 21, 2005Date of Patent: November 21, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7132494Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: May 18, 2004Date of Patent: November 7, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
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Patent number: 7132558Abstract: The invention discloses novel series of silicone esters, which are useful as antioxidants on skin. The products are produced using for a variety of hydroxyl containing actives such as vitamin A (retinol), vitamin A-2, and vitamin E. Compounds of the invention are prepared by the esterification of (a) a specific silicone methyl ester and (c) a hydroxyl functional active. The esters of the present invention allow for the formulation of personal care products in which the “active” can be formulated into a variety of solvents without the loss of activity.Type: GrantFiled: February 12, 2004Date of Patent: November 7, 2006Assignee: SurfaTech CorporationInventors: Anthony J. O'Lenick, Jr., Thomas G. O'Lenick
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Patent number: 7122692Abstract: Process for the preparation of organosilylated carboxylate monomers comprising the step of reacting an acyloxysilane with an unsaturated carboxylic acid, the monomers and their use as comonomer unit in the binder of antifouling coating compositions.Type: GrantFiled: September 19, 2002Date of Patent: October 17, 2006Assignee: Sigma Coatings B.V.Inventors: Mark Plehiers, Marcel Vos, Michel Gillard
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Patent number: 7101949Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: January 21, 2005Date of Patent: September 5, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7091299Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: January 21, 2005Date of Patent: August 15, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7026499Abstract: The invention relates to linear carboxy-functional organosiloxane compounds of the general formula (I) in which a is from 1 to 200, R1 are identical or different aliphatic or aromatic hydrocarbon radicals and R2 is —(Y)[O(C2H4-b(R3)bO)c(CdH2dO)e]fX, and the use thereof for the treatment of the surface of leather.Type: GrantFiled: February 2, 2004Date of Patent: April 11, 2006Assignee: Goldschmidt GmbHInventors: Heike Buskies, Manfred Krakenberg, Sascha Oestreich, Stefan Stadtmüller
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Patent number: 7022749Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: September 18, 2003Date of Patent: April 4, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7009023Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: September 18, 2003Date of Patent: March 7, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7009024Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: September 18, 2003Date of Patent: March 7, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7005494Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: October 23, 2003Date of Patent: February 28, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 7005281Abstract: The invention relates to a process for preparing organosilicon group containing photoinitiators of the formula (I), wherein m is a number from 1 to 200; q is 0 or 1; A is IN-C(O)—O—CHR3—Y— or IN-C(O)—NH—CHR3—Y—; A? is A or R1?; R1 and R1?, R2 and R2? are C1–C18alkyl or phenyl, or —(O)q—SiR1R1?R2; R3 is hydrogen or C1–C6alkyl, Y is a divalent group selected from C1–C10alkeylene, C2–C10alkenylene or —(CH2)b—O—(CH2)a—; and b are each independently of the other a number of 1 to 6; IN is a photolabile functional moiety of the formula (II) or (III), wherein R4 is hydrogen or —C(O)—C(O)—OH or —C(O)—C(O)—OC1–C6alkyl and n is 1–3; R5 and R6 are C1–C12alkyl or together are cycloC5–C7alkyl; R7 is hydroxy, C1–C6alkoxy or morpholinyl; X is —(CH2)a—, —(CH2)b—O—(CH2)a— or —(CH2)b—O—CO—(CH2)a—; a and b are each independently of the other a number of 1 to 6; whereby the process is characterized in that a photolabile functional moiety containing a carboxy group (IN-COOH) or an alkoxycarbonyl group (IN-CO—OC1–C6alkyl) is reacteType: GrantFiled: February 25, 2003Date of Patent: February 28, 2006Assignee: Ciba Specialty Chemicals Corp.Inventors: Reinhold Öhrlein, Kai-Uwe Schöning, Gabriele Baisch, Jemima Schmidt, Gisèle Baudin, Tunja Jung
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Patent number: 6992162Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: October 23, 2003Date of Patent: January 31, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6989430Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: October 23, 2003Date of Patent: January 24, 2006Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler
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Patent number: 6974500Abstract: To provide a primer composition having an excellent balance between storage stability and adhesiveness, while permitting a longer open time. The primer composition includes: a compound (a) represented by the following formula (1): and an organic solvent (b).Type: GrantFiled: August 18, 2003Date of Patent: December 13, 2005Assignee: The Yokohama Rubber Co., Ltd.Inventors: Akihiro Miyata, Kazunori Ishikawa, Hideyuki Matsuda
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Patent number: 6933401Abstract: The present invention relates to a process comprising the steps of reacting in the presence of an epoxide opening catalyst, a substituted epoxide, and preferably a silicone containing substituted epoxide with at least one carboxylic acid and at least one protecting agent to form a vicinal dialkyl ester or a vicinal disilyl ester.Type: GrantFiled: June 30, 2003Date of Patent: August 23, 2005Inventors: Frank Molock, Joseph R. Hepting, Shivkumar Mahadevan
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Patent number: 6930194Abstract: Siloxane bischloroformates are prepared in a continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide. While very high levels (>95%) of conversion of the siloxane bisphenol to the corresponding siloxane bischloroformate are achieved using a flow reactor according to the method of the invention, only more modest conversion (˜90%) of the siloxane bisphenol to the corresponding siloxane bischloroformate is attained when analogous batch processes are employed. The process holds promise for use in the manufacture of silicone-containing copolycarbonates which requires high purity siloxane bischloroformate intermediates.Type: GrantFiled: December 17, 2003Date of Patent: August 16, 2005Assignee: General Electric CompanyInventors: James Manio Silva, David Michel Dardaris, Gary Charles Davis
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Patent number: 6916865Abstract: The present invention provides an organic carboxylate composition that has long working life, cures epoxy resins, and improves adhesive properties, and also provides a method for producing the same. An organic carboxylate composition, obtained by heating and mixing a basic silane coupling agent and an amine compound with a softening point or melting point of 40° C. or greater together with an organic carboxylic acid; a method for producing the same; an additive for epoxy resin that contains this as the active ingredient thereof; and an epoxy resin composition containing the same. The basic silane coupling agent should preferably be a specific imidazole-group containing silane coupling agent, amino group-containing silane coupling agent, dialkylamino group-containing silane coupling agent, monomethylamino group-containing silane coupling agent, benzimidazole group-containing silane coupling agent, benzotriazole group-containing silane coupling agent, and pyridine ring-containing silane coupling agent.Type: GrantFiled: August 27, 2002Date of Patent: July 12, 2005Assignee: Nikko Materials Co., Ltd.Inventors: Masashi Kumagai, Takashi Ouchi, Katsuyuki Tsuchida
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Patent number: 6908978Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more siloxysilane monomers or the copolymerization of one or more siloxysilane monomers with one or more aromatic or non-aromatic non-siloxy monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: November 2, 2001Date of Patent: June 21, 2005Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6906162Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: October 23, 2003Date of Patent: June 14, 2005Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6881809Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: May 18, 2004Date of Patent: April 19, 2005Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
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Patent number: 6881808Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: September 18, 2003Date of Patent: April 19, 2005Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6849668Abstract: A multi-functional photoinitiator of formula (I) R1m—Q—(A1—PI)n??(I) wherein Q is a heteroatom selected from Si, Ti, Zr and Sn or any two independently selected such heteroatoms linked by a covalent bond or a by C1-16 (preferably C1-9) alkylene group, n is at least 2 and n+m=the functionality of Q, each R1 is the same or different and is a non-photoinitiator group; each group PI is the same or different and is a photoinitiator group. Each —A1— is the same or different and is selected from linking groups of formula —(A2)p—Z— wherein p has an average of from 1 to 10, preferably from 3 to 5 and the groups —A2— are either (a) each independently selected from C2-4 alkyleneoxy groups; or (b) each independently selected from groups of formula —O—(CH2)qCO— wherein q is from 3 to 5, and Z is selected from —O—, —S— and —NR6— where R6 is C1-6 alkyl.Type: GrantFiled: August 4, 2000Date of Patent: February 1, 2005Assignee: Sun Chemical CorporationInventors: Roger Edward Burrows, Shaun Lawrence Herlihy, Derek Ronald Illsley
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Patent number: 6849755Abstract: An organosilicon compound represented by the following general formula (1): wherein R1 is a hydrogen atom, a phenyl group or a halogenated phenyl group; R2 is a hydrogen atom or a methyl group; R3's are each a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms; X is a hydrolyzable group; Z1 is —R4—, —R4O— or —R4(CH3)2SiO—, where R4 is a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; Z2 is an oxygen atom or a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; and m is 0, 1 or 2 and n is 0, 1 or 2. When incorporated in silicone compositions, the organosilicon compound acts as a cross-linking agent having well-balanced photopolymerizability and condensation curability.Type: GrantFiled: October 26, 2001Date of Patent: February 1, 2005Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Toshiyuki Ozai, Hiroyasu Hara, Yoshifumi Inoue, Tomoyuki Goto
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Patent number: 6846897Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: May 18, 2004Date of Patent: January 25, 2005Assignee: Bausch and Lomb, Inc.Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
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Patent number: 6831076Abstract: The present invention relates to epothilon derivatives and to their use.Type: GrantFiled: June 25, 2003Date of Patent: December 14, 2004Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)Inventors: Gerhard Hoefle, Michael Kiffe
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Publication number: 20040248849Abstract: The present invention relates to novel antidiabetic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel 3-aryl-&agr;-oxy substituted propanoic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs and pharmaceutically acceptable compositions containing them. Formula (I) where R1 represents t-butyldimethyl silyl, trimethyl silyl or alkoxyalkyl group; R2 represents hydrogen or substituted or unsubstituted (C1-C6)alkyl group.Type: ApplicationFiled: July 28, 2004Publication date: December 9, 2004Inventors: Rajender Kumar Potlapally, Venkata Rama Murali Krishna Reddy Velagala, Ramabhadra Sarma Mamillapalli, Om Reddy Gaddam
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Patent number: 6815554Abstract: A process for preparing unsaturated organosilanes containing organic carbonyloxy groups and having the formula (R1O)3−nR2nSi—X—OC(O)C(R3)═CR32 (I), where R1, R2, and R3 are hydrocarbon groups optionally containing interspersed ether linkages, and optionally substituted, X is an alkylene group, optionally containing ether linkages, and n is 0 to 3, by reacting haloorganofunctional silicon compounds of the formula (R1O)3−nR2nSi—X—Y (II), where Y is a halogen atom, with a salt of an unsaturated organic carboxylic acid of the formula M+[−OC(O)C(R3)═CR32]o (III), where M is an alkali or alkaline earth metal and o is 0 or 1 depending on the valence of M, in the presence of a phosphonium salt as phase transfer catalyst.Type: GrantFiled: April 10, 2002Date of Patent: November 9, 2004Assignee: Wacker-Chemie GmbHInventors: Juergen Pfeiffer, Peter John
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Publication number: 20040215032Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.Type: ApplicationFiled: May 18, 2004Publication date: October 28, 2004Inventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
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Publication number: 20040167100Abstract: The present invention provides illudin analogs of the general formula (I): 1Type: ApplicationFiled: October 27, 2003Publication date: August 26, 2004Applicant: The Regents of the University of CaliforniaInventors: Trevor C. McMorris, Michael J. Kelner
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Patent number: 6762271Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, contact lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based silyl monomers or the copolymerization of one or more aromatic-based silyl monomers with one or more aromatic or non-aromatic non-siloxy-based monomers, hydrophobic monomers or hydrophilic monomers.Type: GrantFiled: November 2, 2001Date of Patent: July 13, 2004Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye, David P. Vanderbilt
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Patent number: 6753432Abstract: The present invention is concerned with a novel process for the preparation of compounds of formula I comprising bromomethylation or chloromethylation of a compound of formula II and subsequent reaction with a compound of formula IV The compounds of formula I and the corresponding salts, e.g. the sodium salts, are pharmaceutically active substances.Type: GrantFiled: August 5, 2003Date of Patent: June 22, 2004Assignee: Hoffmann-La Roche Inc.Inventor: Michelangelo Scalone
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Patent number: 6730767Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: November 2, 2001Date of Patent: May 4, 2004Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6723816Abstract: Optically transparent, relatively high refractive index polymeric compositions and ophthalmic devices such as intraocular lenses, corneal inlays and contact lenses made therefrom are described herein. The preferred polymeric compositions are produced through the polymerization of one or more aromatic-based siloxane macromonomers or the copolymerization of one or more aromatic-based siloxane macromonomers with one or more non-siloxy aromatic-based monomers, non-aromatic-based hydrophobic monomers or non-aromatic-based hydrophilic monomers.Type: GrantFiled: November 2, 2001Date of Patent: April 20, 2004Assignee: Bausch & Lomb IncorporatedInventors: Joseph C. Salamone, Jay F. Kunzler, Richard M. Ozark, David E. Seelye
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Patent number: 6717003Abstract: This invention relates to a powder which is surface-treated by a novel silicone compound, and to a makeup containing this powder. In particular, it relates to a silicone compound which has good compatibility with oils such as ester oils and triglycerides or silicone oils, and to a makeup with a smooth feel, excellent dispersibility and excellent emulsification stability.Type: GrantFiled: February 2, 2001Date of Patent: April 6, 2004Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Tetsuo Nakanishi, Ichiro Ono, Toru Shimizu
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Publication number: 20040039218Abstract: Siloxane bischloroformates are prepared in a continuous process by phosgenating siloxane bisphenols in a flow reactor using a substantial excess of phosgene and sodium hydroxide. While very high levels (>95%) of conversion of the siloxane bisphenol to the corresponding siloxane bischloroformate are achieved using a flow reactor according to the method of the invention, only more modest conversion (˜90%) of the siloxane bisphenol to the corresponding siloxane bischloroformate is attained when analogous batch processes are employed. The process holds promise for use in the manufacture of silicone-containing copolycarbonates which requires high purity siloxane bischloroformate intermediates.Type: ApplicationFiled: August 16, 2002Publication date: February 26, 2004Applicant: General Electric CompanyInventors: James Manio Silva, David Michel Dardaris, Gary Charles Davis
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Patent number: 6646144Abstract: The present invention relates to cranberry seed oil derivatives derived by the reaction of dimethicone copolyol and cold pressed cranberry seed oil. The choice of cold pressed cranberry seed oil as a raw material in the preparation of the compounds of the present invention is critical, since it has been found that the cold pressed cranberry seed oil contains antioxidants, antimicrobial compounds and which when reacted with a water soluble or water dispersible silicone result in products that deliver said actives to the skin and hair, resulting in protection of the skin and hair from environmental factors such as acid rain, ozone attack and UV degradation.Type: GrantFiled: November 4, 2002Date of Patent: November 11, 2003Assignee: Zenitech LLCInventors: Kenneth Klein, Irwin Paleksky, Anthony J. O'Lenick, Jr.
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Publication number: 20030166957Abstract: The invention concerns organosilicon compounds, their method of preparation and their use as coupling agents for depositing, at the surface of a solid support, an organised self-assembled monolayer. The invention also concerns a method for obtaining solid supports whereof the surface is modified by an organised self-assembled monolayer comprising a system of said organosilicon compounds, and the use of said solid supports for biomolecular synthesis or immobilisation.Type: ApplicationFiled: November 12, 2002Publication date: September 4, 2003Inventors: Bernard Benneteau, Jamal Bousbaa, Franck Choplin
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Publication number: 20030130535Abstract: Organosilicon compounds of the general formula I and/or II 1Type: ApplicationFiled: August 6, 2002Publication date: July 10, 2003Applicant: Degussa AG,Inventors: Ulrich Deschler, Roland Krafczyk, Hans-Detlef Luginsland, Karsten Korth, Ingo Kiefer, Michael Horn
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Publication number: 20030120073Abstract: Protein tyrosine phosphatases (PTPs) are implicated in a number of disease processes, including autoimmune diseases, glucose intolerance, diabetes, obesity and certain types of proliferative diseases such as cancer and psoriasis. The present invention discloses novel &agr;-ketocarboxylic acid inhibitors of PTPs, methods for synthesizing said inhibitors, and methods for using pharmaceutical compositions of the inhibitors to treat PTP-mediated disorders, diseases or dysfunctions. The compositions described herein can also be used as diagnostic and screening tools to elucidate complex signal transduction pathways involving PTPs or to identify PTP-mediated disease states.Type: ApplicationFiled: April 5, 2002Publication date: June 26, 2003Inventor: Christopher T. Seto
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Publication number: 20030108676Abstract: A glass coating agent is provided which is adapted for application onto the surface of a glass substrate and, upon heating, forms a metal oxide layer.Type: ApplicationFiled: November 26, 2002Publication date: June 12, 2003Applicants: KIRIN BEER KABUSHIKI KAISHA, NITTO KASEI CO., LTD.Inventors: Eihaku Shimamura, Katsuhiro Imashita, Tsutomu Amano, Tatsuya Nagai, Takayuki Okada, Hitoshi Tabuchi, Masaaki Katayama
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Patent number: 6576734Abstract: Provided are modified carboxyl-terminated polyorganosiloxanes having a mean molecular weight of from 500 to 120,000 and represented by the following formula (1), and a method for producing them. The modified polyorganosiloxanes have a carboxyl group at one terminal position, and have a polyoxyalkylene moiety in the center of the molecular chain. They are highly miscible with various polar solvents and monomers. The method for producing them comprises reacting a polyorganosiloxane having a hydroxyl group at one terminal position and having a polyoxyalkylene moiety in the center of the molecular chain, with a cyclic acid anhydride having a specific structure, and it does not require plural reaction steps. In the method, various types of carboxyl-terminated polyorganosiloxanes can be easily produced, depending on the type of the cyclic acid anhydride used.Type: GrantFiled: November 28, 2000Date of Patent: June 10, 2003Assignee: Chisso CorporationInventors: Takashi Matsuo, Youichi Kimae
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Patent number: 6559329Abstract: The present invention is directed to a process comprising deblocking a silane of the formula (RIC(═O)O)yC6RII6−y−z[CxH2xSi(ORIII)3−a(RIV)a]z where RI is H, CH3 or RVO; RII is H or RVO; RIII is alkyl, phenyl or acyl from 1 to 6 carbon atoms; RIV is hydrogen, alkyl or phenyl from 1 to 6 carbon atoms; RV is a linear or branched alkyl group from 1 to 4 carbon atoms; y is an integer from 1 to 3; z is an integer from 1 to 3; x is an integer from 2 to 6 and a is an integer from 0 to 2 to yield a phenolic silane. Also disclosed are processes for making a blocked silane having the above formula.Type: GrantFiled: October 17, 2001Date of Patent: May 6, 2003Assignee: Crompton CorporationInventors: Eric R. Pohl, Scot M Turner
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Patent number: 6552212Abstract: Compositions of matter comprising benzoate esters of hydroxyl terminated polyether polysiloxane copolyols, in particular dimethicone copolyol benzoates, and process for preparing same. The benzoate esters are useful for personal care cleansing products, such as bar and liquid soaps, skin and hair care products and textiles and fibers. The compounds are prepared by reacting benzoic acid with hydroxyl terminated polyether polysiloxane copolyols.Type: GrantFiled: May 14, 2001Date of Patent: April 22, 2003Assignee: Finetex, Inc.Inventors: Ismail I. Walele, Samad A. Syed