Silicon And Carbon Bonded Directly To The Same Oxygen Patents (Class 556/482)
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Patent number: 4650895Abstract: High purity organometallic compounds can be obtained by the process which comprises subjecting an organometallic compound in a liquid state under stirring to preliminary oxidation or hydrolysis in a proportion of about 0.1 to 50% by weight of the organometallic compound to form solid reaction products, and separating by distillation the unreacted organometallic compound from the solid reaction products to recover the purified organometallic compound; and high purity metallic compounds such as a solid metallic hydroxide or oxide can be obtained by the process which comprises following the process as mentioned above, oxidizing or hydrolyzing completely the recovered purified organometallic compound.Type: GrantFiled: January 30, 1984Date of Patent: March 17, 1987Assignee: Sumitomo Chemical Company, LimitedInventors: Hidekimi Kadokura, Hiroshi Umezaki, Yoshihiro Higuchi
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Patent number: 4645850Abstract: The invention is directed to silyl alkyl and silylaralkyl substituted cyclopentadienes which have a hydrolyzable group attached to the silicon atom, a process for their production and peroxide cross-linkable synthetic resin and rubber mixtures containing them.Type: GrantFiled: July 17, 1985Date of Patent: February 24, 1987Assignee: Degussa AktiengesellschaftInventors: Ulrich Deschler, Peter Panster, Peter Kleinschmit, Siegfried Wolff, Ewe-Hong Tan
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Patent number: 4585885Abstract: A silyl-enol ether of the formula ##STR1## wherein n stands for the number and X stands for a group ##STR2## or n stands for the number 1 and X stands for the 6,11-dimethylhexadeca-2,4,6,8,10,12,14-heptaene-2,15-diyl group, the symbols R.sup.1 have the same or different significances and denote alkyl groups, and the symbol R.sup.2 represents a trialkylsiloxy group --OSi(R.sup.1).sub.3 or an ether group,is oxidized with percarboxylic acid and, if desired, the resulting .alpha.-siloxy ketone is hydrolyzed to an .alpha.-hydroxy ketone. This process is especially suitable for the manufacture of astaxanthin.Type: GrantFiled: August 19, 1983Date of Patent: April 29, 1986Assignee: Hoffmann-La Roche Inc.Inventors: Kurt Bernhard, Robert K. Muller, Robert Spruijtenburg
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Patent number: 4579966Abstract: Novel terpenoid alkoxysilanes having the general formula: ##STR1## wherein Y is hydrogen or Si(R.sup.2).sub.n X.sub.m (OR.sup.3).sub.3-(N-m), Z is hydrogen or Si(R.sup.2).sub.n X.sub.m (OR.sup.3).sub.3-(n+m), one of Y and Z being Si(R.sup.2).sub.n X.sub.m (OR.sup.3).sub.3-(n+m), R.sup.2 and R.sup.3 being the same or different C.sub.1 -C.sub.3 alkyl group, X is halogen, m and n are independently selected from 1 and 0, and II W is Si(R.sup.2).sub.n X.sub.m (OR.sup.3).sub.3-(n+m), where R.sup.2, R.sup.3, X, n and m are as defined above.Type: GrantFiled: January 14, 1985Date of Patent: April 1, 1986Assignee: SCM CorporationInventors: Ralph J. De Pasquale, Paul W. Kremer
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Patent number: 4576758Abstract: The present invention relates to analogs of lipoxin B (LX-B) and discloses the anti-inflammatory uses for these analogs. Particularly, the present invention relates to analogs of 5D,14,15-trihydroxy-6,8,10,12-eicosatetraenoic acid, including certain 5-epi-, 8,9-didehydro-, 6-iso, 6,7-dihydro-7.alpha.-hydroxy, and 6,7-dihydro-7.beta.-hydroxy derivatives.Type: GrantFiled: June 1, 1984Date of Patent: March 18, 1986Assignee: The Upjohn CompanyInventor: Joel Morris
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Patent number: 4562298Abstract: A process for producing novel compositions including optically active molecules of nordihydroguaiaretic acid (d,1-2,3-dimethyl,1,4-bis(3,4-dihydroxyphenyl)butane) and intermediates, starting with 1,4-bis(3,4-dimethoxyphenyl)butanone, or other structurally similar composition having oxy substituents at the 3,4-phenyl positions, comprising (1) forming the corresponding butanol; (20) forming the corresponding 1,4-butane ether or siloxy composition; (3) cleaving the oxy substituent from the butane chain at the 1 and 4 positions; (4) dealkylating the phenols at the 3,4 positions to leave hydroxy substituents with hydrobromic acid reflux for 8 to 10 hours. Optical orientation is preserved throughout.Type: GrantFiled: October 25, 1982Date of Patent: December 31, 1985Assignee: Chemex Pharmaceuticals, Inc.Inventors: Robert M. Parkhurst, Ronald S. Pardini
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Patent number: 4504663Abstract: The present invention concerns novel heterocyclic aminoalcoyl derivatives having the formula: ##STR1## wherein n=1, 2 or 3; A represents a nitrogen atom or the CH group, X=CH.sub.2 or CH.sub.2 O; R represents a phenyl nucleus possibly substituted; NR.sub.1 R.sub.2 =amino, methylamino, N,N-dialkylamino or an heterocyclic radical; and R.sub.3 =H, halogen, alkyl, alkyloxy or methoxy.These derivatives are useful as drugs, especially as analgesics and antidepressants.Type: GrantFiled: November 15, 1983Date of Patent: March 12, 1985Assignee: Delalande S.A.Inventors: Gerard H. Moinet, Philippe L. Dostert, Guy R. Bourgery
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Patent number: 4500725Abstract: A compound represented by the general formula:R.sub.s Si(OR').sub.t (OR").sub.4-s-twherein R represents methyl, ethyl, or vinyl; R'O represents ##STR1## R" represents methyl or ethyl; s represents 0 or 1; and t represents an integer of from 1 to 4; and fragrant agent formed by impregnating solid matter with a compound represented by the general formula:R.sup.3.sub.a Si(OR.sup.4).sub.b (OR.sup.5).sub.cwherein R.sup.3, R.sup.4 and R.sup.5 represent a hydrocarbon group, with the proviso that R.sup.5 is derived from an alcohol of the general formula R.sup.5 OH that develops aroma; and a, b and c are each an integer, or a derivative thereof.Type: GrantFiled: July 28, 1982Date of Patent: February 19, 1985Assignee: Chisso CorporationInventors: Jiichiro Yemoto, Ryokichi Tarao, Yoshio Yamamoto
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Patent number: 4487953Abstract: Compounds of Formula (I) ##STR1## wherein the 9-bromine atom can be in the .alpha.- or .beta.-position,R.sub.1 is CH.sub.2 OH or C(O)OR.sub.2, wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, or a heterocyclic residue; or R.sub.1 is C(O)NHR.sub.3 wherein R.sub.3 is an acid residue or R.sub.2 ; andA is --CH.sub.2 --CH.sub.2 -- or cis --CH.dbd.CH--;B is --CH.sub.2 --CH.sub.2 --, trans --CH.dbd.CH--, or --C.tbd.C--;W is a free or functionally modified hydroxymethylene group or a free or functionally modified ##STR2## wherein the OH-group can be in the .alpha.- or .beta.-position; D and E together are a direct bond; orD is straight-chain, branched, or cyclic alkylene of 1-10 carbon atoms, optionally substituted by fluorine atoms; andE is oxygen, sulfur, a direct bond --C.tbd.C--, or --CR.sub.6 .dbd.CR.sub.7 --, wherein R.sub.6 and R.sub.7 are different from each other and each is hydrogen, chlorine, or C.sub.1 -C.sub.4 -alkyl;R.sub.4 is a free or functionally modified hydroxy group;R.sub.Type: GrantFiled: December 6, 1982Date of Patent: December 11, 1984Assignee: Schering AktiengesellschaftInventors: Werner Skuballa, Bernd Raduechel, Norbert Schwarz, Helmut Vorbrueggen, Walter Elger
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Patent number: 4478990Abstract: A room temperature curing elastic composition useful as a sealing material which comprises as a main component a polymer produced from(a) at least one acrylic ester monomer of the formula:CH.sub.2 .dbd.CHCOOR.sub.1wherein R.sub.1 is an alkyl having 2 to 8 carbon atoms;(b) at least one member selected from the group consisting of vinylalkoxysilane of the formula: ##STR1## wherein R.sub.2 is an alkyl having 1 to 4 carbon atoms, X is methoxy or ethoxy, and a is 0, 1 or 2; and a (meth)acryloxyalkoxysilane of the formula: ##STR2## wherein R.sub.3 is hydrogen or methyl, R.sub.4 is a divalent hydrocarbon group, R.sub.5 is an alkyl having 1 to 4 carbon atoms, Y is methoxy or ethoxy, and b is 0, 1 or 2; and(c) a chain transfer agent having a mercapto group.Type: GrantFiled: April 26, 1982Date of Patent: October 23, 1984Assignee: Sunstar Giken Kabushiki KaishaInventors: Kiyoshi Kohno, Satoshi Nishikawa, Yoshiya Hattori, Kohji Kitao
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Patent number: 4477388Abstract: Vinylstannyl derivatives and the processes for their conversion to vinyliodides, vinylbromides and vinyllithium reagents. The vinylstannyl, vinyliodides, vinylbromide derivatives and vinyllithiums are useful as intermediates for the preparation of prostaglandin analogs.Type: GrantFiled: October 7, 1983Date of Patent: October 16, 1984Assignee: American Cyanamid CompanyInventors: Middleton B. Floyd, Jr., Charles V. Grudzinskas, Sow-Mei L. Chen
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Patent number: 4469881Abstract: [2-(p-t-Butylphenyl)ethyl]silanes are provided having the general formula:Si(B).sub.x (R).sub.y (A).sub.zwherein B is a (p-t-butylphenyl)ethyl moiety, R is an alkyl or aryl moiety and A is a hydrolyzeable moiety; x equals 1 or 2, y equals 0, 1 or 2 and z equals 1, 2 or 3 such that x plus y plus z equals 4. The bulky substituted silanes are produced by the hydrosilylation of p-t-butylstyrene.[2-(p-t-Butylphenyl)ethyl] substituted disiloxanes are also provided, having the general formula:(B).sub.x (R).sub.y (A).sub.z Si--O--Si(A).sub.z (R).sub.y (B).sub.xwherein B, R, A, x, y and z are as defined above except that z equals 0,1 or 2 and x plus y plus z equals 3. The bulky substituted disiloxanes are produced by the hydrolysis of above-described bulky substituted silanes.Type: GrantFiled: September 27, 1982Date of Patent: September 4, 1984Assignee: Petrarch Systems Inc.Inventor: Barry C. Arkles
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Patent number: 4455330Abstract: The insulation resistance of glass fibers is improved by contacting the glass fibers with monofunctional silanes such as phenyldimethylethoxysilaneType: GrantFiled: August 4, 1982Date of Patent: June 19, 1984Assignee: Owens-Corning Fiberglas CorporationInventors: Gary M. Nishioka, Sheldon P. Wesson
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Patent number: 4454339Abstract: 9-Fluoroprostane derivatives of Formula I ##STR1## wherein R.sub.1 is CH.sub.2 OH or ##STR2## wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, or a heterocyclic residue; or R.sub.1 is the residue ##STR3## wherein R.sub.3 is an acid residue or R.sub.2 and A is --CH.sub.2 --CH.sub.2 -- or cis--CH.dbd.CH--,B is --CH.sub.2 --CH.sub.2 --, trans--CH.dbd.CH-- or --C.tbd.C,W is a free or functionally modified hydroxymethylene group wherein the OH-group can be in the .alpha.- or .beta.-position,D and E jointly are a direct bond orD is straight-chain or branched alkylene or alkenylene of 1-10 carbon atoms which can optionally be substituted by fluorine atoms, and E is oxygen or sulfur, a direct bond, --C.tbd.C-- or --CR.sub.6 .dbd.CR.sub.7 -- wherein R.sub.6 and R.sub.7 differ from each other and each is hydrogen, chlorine, or alkyl,R.sub.4 is a free or functionally modified hydroxy group, andR.sub.5 is hydrogen, an optionally substituted aliphatic group, e.g.Type: GrantFiled: July 6, 1982Date of Patent: June 12, 1984Assignee: Schering AktiengesellschaftInventors: Werner Skuballa, Bernd Raduechel, Norbert Schwarz, Helmut Vorbrueggen, Walter Elger, Olaf Loge, Michael-Harold Town
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Patent number: 4454056Abstract: The invention is directed to a process for the production of zeolites of the type Na A4 having the surface modified with organosilanes. The organosilane must have at least one alkoxy group bonded to the silicon atom. The modified zeolites of the invention are used in washing and cleansing agents.Type: GrantFiled: March 9, 1983Date of Patent: June 12, 1984Assignee: Degussa AktiengesellschaftInventors: Udo Kittelmann, Manfred Diehl, Roland Bergmann, Gunter Stadtmuller
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Patent number: 4431851Abstract: The present invention concerns compounds of the formula ##STR1## wherein n=1, 2 or 3; and R' represents phenyl or orthofluorophenyl. Said compounds are used as intermediates in the preparation of heterocyclic aminoalkyl derivatives which are useful as analgesics and antidepressants.Type: GrantFiled: March 8, 1983Date of Patent: February 14, 1984Assignee: Delalande S.A.Inventors: Gerard H. Moinet, Philippe L. Dostert, Guy R. Bourgery
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Patent number: 4430504Abstract: Silyl ethers obtainable from aryl silyl ketones and mono-, di-, tri- or tetra-chlorosilanes in the presence of base metals are eminently suitable for use as initiators for radical polymerization reactions.Type: GrantFiled: December 10, 1982Date of Patent: February 7, 1984Assignee: Bayer AktiengesellschaftInventors: Knud Reuter, Rolf Dhein
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Patent number: 4425278Abstract: A complex compound of a metal salt or metalloid salt and an ansolvo-acid or proton-acid, of the general formula IM.sub.n.sup.m.X.sub.m.sup.n.pY.qZ (I)in which M is a m-valent cation of a metal or metalloid, a metal-oxy or metal-dioxy cation or a hydrogen atom, X is a n-valent anion of a n-basic inorganic proton-acid or of a n-basic organic acid selected from the group of the aliphatic and cycloaliphatic carboxylic acids with up to 8 C atoms, which can be substituted by halogen and/or hydroxyl groups, the aromatic monocarboxylic, dicarboxylic and tricarboxylic acids, which may be substituted by hydroxyl, halogen and/or nitro groups, the organic oxyacids of phosphorus and sulphur, the organic thioacids of phosphorus, and the mercaptans, the inorganic or organic acid having a pK.sub.a value of at most 15.Type: GrantFiled: June 29, 1981Date of Patent: January 10, 1984Assignee: Ciba-Geigy CorporationInventors: Hermann O. Wirth, Hans-Helmut Friedrich
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Patent number: 4421654Abstract: What is disclosed is the preparation of novel silanes, their reaction products on various substrates and the use of the treated substrates to extract metal ions from solution.Type: GrantFiled: July 15, 1982Date of Patent: December 20, 1983Assignee: Dow Corning CorporationInventor: Edwin P. Plueddemann
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Patent number: 4381377Abstract: A homo- or copolymer of a 1,3-diene bound to reactive silyl groups, whereby it contains 0.4-12% by weight of bound silicon, is prepared by reacting, at a temperature of 190.degree.-300.degree. C., a 1,3-diene homo- or copolymer, with more than 1% of its aliphatic double bonds in conjugation and having a molecular weight (Mn) of 400-6,000, with a silane of the formula ##STR1## wherein R is an unsaturated aliphatic hydrocarbon radical of 2-20 carbon atoms,X is halogen, C.sub.1-6 alkoxy, C.sub.1-6 alkoxyalkoxy, C.sub.6-12 aryloxy, C.sub.1-8 alkanoyloxy, C.sub.1-6 ketoximato or C.sub.1-10 hydrocarbylamido, andY and Z are independently one of the X groups, hydrogen, alkyl of 1-8 carbon atoms, cycloalkyl of 5-12 carbon atoms, or optionally substituted phenyl.Type: GrantFiled: February 2, 1981Date of Patent: April 26, 1983Assignee: Chemische Werke Huels, AGInventors: Wolfgang Kampf, Roland Streck, Horst-guenter Haag
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Patent number: 4377706Abstract: Polyalkoxysilylenolethers, for example, methyldimethoxyisopropenoxysilane, are provided and a method for making such silanes. The dialkoxysilylenolethers can be used as end-capping silanes for making noncorrosive RTV compositions.Type: GrantFiled: June 26, 1981Date of Patent: March 22, 1983Assignee: General Electric CompanyInventor: John E. Hallgren
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Patent number: 4360467Abstract: The preparation of racemic 1R, 4R, 5R-5-(4', 8'-dimethyl-5'-hydroxy-7'-nonenyl)-5-methyl-8-oxabicyclo[3.2.1]-octane-1-a cetic acid is described. The cycloheptane compounds are active uteroevacuant agents.Type: GrantFiled: September 8, 1981Date of Patent: November 23, 1982Assignee: Ortho Pharmaceutical CorporationInventor: Ramesh M. Kanojia
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Patent number: 4357474Abstract: Synthesis of the insect pheromone (9Z,11E)-9,11-hexadecadienal of the sugarcane borer, Diatraea saccharalis (F.), and intermediates therefor.Type: GrantFiled: March 9, 1981Date of Patent: November 2, 1982Assignee: Zoecon CorporationInventors: Robert L. Carney, Alfred S. T. Lui
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Patent number: 4344992Abstract: A chrysotile asbestos base material is mixed in water containing dissolved alum (aluminum sulphate) prior to addition of the organo-silane coating.Type: GrantFiled: June 30, 1981Date of Patent: August 17, 1982Assignee: Union Carbide CorporationInventor: Sundaresan Ramachandran
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Patent number: 4336148Abstract: A complex compound of a metal salt or metalloid salt and an ansolvo-acid or proton-acid, of the general formula IM.sub.n.sup.m.X.sub.m.sup.n.pY.qZ (I)in which M is a m-valent cation of a metal or metalloid, a metal-oxy or metal-dioxy cation or a hydrogen atom, X is a n-valent anion of a n-basic inorganic proton-acid or of a n-basic organic acid selected from the group of the aliphatic and cycloaliphatic carboxylic acids with up to 8 C atoms, which can be substituted by halogen and/or hydroxyl groups, the aromatic monocarboxylic, dicarboxylic and tricarboxylic acids, which may be substituted by hydroxyl, halogen and/or nitro groups, the organic oxyacids of phosphorus and sulphur, the organic thioacids of phosphorus, and the mercaptans, the inorganic or organic acid having a pK.sub.a value of at most 15.Type: GrantFiled: August 30, 1978Date of Patent: June 22, 1982Assignee: Ciba-Geigy CorporationInventors: Hermann O. Wirth, Hans-Helmut Friedrich
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Patent number: 4310640Abstract: A composition comprising (a) an organic compound having at least one hydrolyzable silyl group and (b) an organic amine and/or an alkali metal hydroxide. The composition is curable upon exposure to moisture, and has superior properties, such as hardness, toughness and stain resistance, when used for example as a coating. The composition can be utilized as a coating material.Type: GrantFiled: May 16, 1980Date of Patent: January 12, 1982Assignee: Kanegafuchi Kogaku Kogyo Kabushiki KaishaInventors: Yasushi Kato, Hisao Furukawa, Shoichi Matsumura, Saori Nakatsuka
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Patent number: 4306035Abstract: A process for manufacturing low density high resilience polyurethane foams utilizing as a foam stabilizer selected low molecular weight alkoxysilicon compositions containing from one to 18 silicon atoms in which the alkoxy-modifying group contains from 5 to 18 carbon atoms; solutions of such alkoxysilicon compositions; and the foams derived from such process.Type: GrantFiled: May 30, 1980Date of Patent: December 15, 1981Assignee: Union Carbide CorporationInventors: Feyyaz O. Baskent, James D. Reedy
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Patent number: 4296042Abstract: This process relates to the synthesis of unsaturated aliphatic esters useful as insect sex attractants, including gossyplure, the insect sex pheromone of the pink bollworm moth, Pectinophora gossypiella, and intermediates therefor. The process utilizes a cyclic phosphonium (Wittig) reagent.Type: GrantFiled: June 18, 1980Date of Patent: October 20, 1981Assignee: Syntex (U.S.A.) Inc.Inventors: Joseph M. Muchowski, Michael C. Venuti
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Patent number: 4294975Abstract: The invention provides a novel class of organosilicon compounds which are hydrogenalkenyloxysilanes represented by the general formula ##STR1## in which R.sup.1 is a monovalent hydrocarbon group having from 1 to 8 carbon atoms, R.sup.2, R.sup.3 and R.sup.4 are each a hydrogen atom or a monovalent hydrocarbon group having from 1 to 8 carbon atoms and n is a number of zero, 1 or 2. The silane compounds are readily obtained by the dehydrochlorination reaction between a corresponding hydrogen-containing chlorosilane compound and an .alpha., .beta.-unsaturated aldehyde compound or a ketone compound in the presence of an acid acceptor. The compounds are useful as a modifying agent in the silicone technology and also serve as a curing agent.Type: GrantFiled: May 20, 1980Date of Patent: October 13, 1981Assignee: Shin-Etsu Chemical Co. Ltd.Inventors: Toshio Takago, Masatoshi Arai, Koji Futatsumori
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Patent number: 4276216Abstract: The synthesis of C-4 alkyl analogs of racemic (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyc lo[3.2.1]octane-1-acetic acid and the corresponding (1RS,4RS,5RS)- derivative is described. The dioxabicyclo[3.2.1]octanes are useful as contragestational agents.Type: GrantFiled: July 31, 1980Date of Patent: June 30, 1981Assignee: Ortho Pharmaceutical CorporationInventors: Zoltan G. Hajos, Michael P. Wachter
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Patent number: 4269780Abstract: A process for forming non-polymeric disproportionation products of non-conjugated olefins using catalysts comprising (1) at least one of certain neutral carbene complexes, and (2) at least one of certain compounds of Groups IVa, IVb, Vb, VIb, VIIb, VIII, and Ib of the Periodic Table of the Elements.Type: GrantFiled: December 6, 1979Date of Patent: May 26, 1981Assignee: Phillips Petroleum CompanyInventor: Dennis S. Banasiak
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Patent number: 4243611Abstract: Prostaglandin derivatives having a 19,20-didehydro, a 19-hydroxy, or a 19-keto feature are disclosed, including processes for preparing them and the appropriate intermediates.A typical 19-hydroxy compound of this invention is 19-hydroxy-19-methyl-PGF.sub.2.alpha.Type: GrantFiled: April 2, 1979Date of Patent: January 6, 1981Assignee: The Upjohn CompanyInventor: John C. Sih
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Patent number: 4233453Abstract: This invention disclosed herein relates to pharmacologically active 15-deoxy-16-hydroxy prostaglandin derivatives of the E and F series wherein C.sub.16 is substituted with allenyl.These compounds are active as hypotensives, antisecretory, bronchodilating and fertility control agents.Type: GrantFiled: June 7, 1979Date of Patent: November 11, 1980Assignee: American Cyanamid CompanyInventor: Middleton B. Floyd, Jr.
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Patent number: 4233231Abstract: Vinylstannyl derivatives and the processes for their conversion to vinyliodides, vinylbromides and vinyllithium reagents. The vinylstannyl, vinyliodides, vinylbromide derivatives and vinyllithiums are useful as intermediates for the preparation of prostaglandin analogs.Type: GrantFiled: November 22, 1977Date of Patent: November 11, 1980Assignee: American Cyanamid CompanyInventors: Middleton B. Floyd, Jr., Charles V. Grudzinskas, Sow-Mei L. Chen
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Patent number: 4232166Abstract: The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E and F series wherein C-16 is substituted with hydroxy and methyl and a double bond is introduced between C-19 and C-20. These compounds are active as bronchodilators, anti-ulcer agents and fertility control agents.Type: GrantFiled: June 7, 1979Date of Patent: November 4, 1980Assignee: American Cyanamid CompanyInventor: Allan Wissner
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Patent number: 4228093Abstract: Synthesis of an attractant (11Z,13Z)-11,13-hexadecadienal for the navel orangeworm Amyelois transitella, and intermediates therefor.Type: GrantFiled: October 18, 1979Date of Patent: October 14, 1980Assignee: Zoecon CorporationInventors: Robert L. Carney, Clive A. Henrick
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Patent number: 4206151Abstract: This disclosure describes novel 15-deoxy-16 hydroxy-16-substituted prostanoic acid analogs in which the C-1 carboxyl is replaced by a primary alcohol and carboxylic acid esters, carbonates and carbomates thereof. The prostanoic carbinols and carboxylic acid esters thereof described herein have utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.Type: GrantFiled: December 21, 1978Date of Patent: June 3, 1980Assignee: American Cyanamid CompanyInventor: Charles V. Grudzinskas
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Patent number: 4202988Abstract: This disclosure describes derivatives, analogs, and congeners of prostanoic acid having a terminal cyclic moiety in the .beta.-chain which possess the pharmacological activities associated with the prostaglandins.Type: GrantFiled: March 30, 1977Date of Patent: May 13, 1980Assignee: American Cyanamid CompanyInventors: Allan Wissner, Martin J. Weiss, Karel F. Bernady
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Patent number: 4202822Abstract: Derivatives, analogs, and congeners of prostane having a 1-(hydroxymethyl)-1-oxo-prostane structure in the F.sub.1 series.Type: GrantFiled: December 8, 1977Date of Patent: May 13, 1980Assignee: American Cyanamid CompanyInventor: Allan Wissner
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Patent number: 4198533Abstract: Synthesis of an attractant (11Z,13Z)-11,13-hexadecadienal for the navel orangeworm Amyelois transitella, and intermediates therefor.Type: GrantFiled: February 26, 1979Date of Patent: April 15, 1980Assignee: Zoecon CorporationInventors: Robert L. Carney, Clive A. Henrick
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Patent number: 4197245Abstract: Derivatives, analogs, and congeners of prostane having a 1-(hydroxymethyl)-1-oxo-prostane structure in the A.sub.1 series.Type: GrantFiled: December 8, 1977Date of Patent: April 8, 1980Assignee: American Cyanamid CompanyInventor: Allan Wissner