And Reactant Having Halogen Bonded Directly To Carbon, Which Carbon May Be Single Bonded To Any Element But May Be Multiple Bonded Only To Carbon Patents (Class 558/106)
Having -c(=x)-, wherein x is chalcogen, or cyano attached indirectly to the halogen by acyclic nonionic bonding (Class 558/107)
  • Preparation of halohydrocarbyl phosphonic acid diesters
    Patent number: 7435841
    Abstract: In a process for the production of halohydrocarbyl phosphonic acid diesters via a Michaelis-Arbuzov type reaction which results in high conversion and selectivity of product with ease of purification; the improvement comprises reacting hydrocarbyl halide with trihdydrocarbyl phosphite in a molar ratio of about 6:1 and in the presence of an effective amount of a polarity lowering additive.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: October 14, 2008
    Assignee: Rhodia Inc.
    Inventors: Shiming Wo, John Marshall Baker
  • Synthesis of D-3 phosphorylated phosphoinositides and analogues
    Patent number: 6096916
    Abstract: Disclosed are unique starting materials, reaction sequences and intermediate compounds for the preparation of D-3-phosphorylated phosphoinositides (3-PPI) of unambiguous structure and absolute stereochemistry. The enantiomerically pure D-3-phosphorylated phosphoinositides also provided have many uses, including in the development of diagnostics and therapeutics based on the roles of 3-PPI in intracellular signaling.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: August 1, 2000
    Assignee: Nutrimed Biotech
    Inventor: Rajindra Aneja
  • Cationic phospholipids for transfection
    Patent number: 5695780
    Abstract: A novel class of cationic phospholipids and a novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic lacids. These novel phospholipids are particularly attractive because they are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald
  • Cationic phospholipids for transfection
    Patent number: 5688958
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 18, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Cationic phospholipids for transfection
    Patent number: 5686620
    Abstract: A novel class of cationic phospholipids and novel method for their synthesis are disclosed. The class of phospholipids comprises phosphotriester derivatives of phosphoglycerides and sphingolipids. It has been unexpectedly found that liposomes comprising one or more of these cationic phospholipids are effective in the lipofection of nucleic acids. These novel phospholipids are particularly attractive because of they are not only effective in lipofection, but are extremely cheap and easy to make.
    Type: Grant
    Filed: September 1, 1995
    Date of Patent: November 11, 1997
    Assignee: Northwestern University
    Inventors: Gary W. Ashley, Robert C. MacDonald, Miho Shida
  • Phosphorylation with monomeric metaphosphates
    Patent number: 5334741
    Abstract: Solid substrates with free hydroxyl groups are phosphorylated by thermolysing a solution of phosphoramidate of the formula ##STR1## in the presence of the substrate, whereby metaphosphate is generated which phosphorylates the substrate.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: August 2, 1994
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Louis D. Quin, Stefan Jankowski
  • Process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives
    Patent number: 5138084
    Abstract: A process for the preparation of 4-O-phosphates of dopamine and dopamine derivatives by treatment of a mixture of both 3-O-phosphate and 4-O-phosphate isomers with a strong mineral acid and optional esterification of the so obtained phosphoric ester of dopamine or dopamine derivatives is described.
    Type: Grant
    Filed: November 14, 1990
    Date of Patent: August 11, 1992
    Assignee: SIMES Societa Italiana Medicinali e Sintetici S.p.A.
    Inventors: Cesare Casagrande, Francesco Santangelo
  • O-(perfluoroalkylthiophenyl) (thio or amido) phosphates as pesticides
    Patent number: 4581350
    Abstract: The invention relates to new organic phosphoric acid esters represented by the general formula ##STR1## wherein X represents O, S or NH,Y represents O or S,R.sup.1 represents a lower alkyl group,R.sup.2 represents a lower alkyl group or a lower alkoxy-lower alkyl group,R.sup.3 represents a fluoro-substituted lower alkyl group,Z represents a lower alkyl group, a lower alkoxy group or a halogen atom, andn represents 0 or 2,which can be used as pesticidally active agents.
    Type: Grant
    Filed: May 18, 1984
    Date of Patent: April 8, 1986
    Assignee: Nihon Tokushu Noyaku Seizo K.K.
    Inventors: Junichi Saito, Akio Kudamatsu, Toyohiko Kume, Shinichi Tsuboi
  • Phosphorus functional antimicrobial coatings for metal surfaces
    Patent number: RE48510
    Abstract: The invention relates to quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, processes for preparing quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, antimicrobial coating compositions comprising quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds and method of treating a surface with said compositions to provide a durable, antimicrobial-treated surface.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: April 13, 2021
    Assignee: Nano Safe Coatings Incorporated
    Inventors: Lukasz Porosa, Gideon Wolfaardt, Daniel Foucher