Abstract: A process for the production of a chloride of thiophosphinic acids which comprises reacting an anhydride of a phosphinic acid with thiophosphoryl chloride.
Abstract: The invention relates to certain substituted phenoxypropionaldehyde derivatives, formulations of said derivatives and the use thereof for preemergence or postemergence control of noxious plants, i.e., weeds.
Abstract: New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics.
Type:
Grant
Filed:
November 5, 1986
Date of Patent:
December 29, 1987
Assignee:
Merck & Co., Inc.
Inventors:
William H. Parsons, William R. Schoen, Arthur A. Patchett, Masao Taniguchi
Abstract: A process for the preparation of phosphorus-containing .alpha.-amino nitriles of the general formula I ##STR1## in which R.sub.1 and R.sub.2 denote (substituted) alkyl, aryl, aralkyl or cycloalkyl, R.sub.3 denotes H, alkyl, phenalkyl, acyl, alkoxycarbonyl or aryloxycarbonyl, and n denotes zero or one, by reaction of corresponding acylals with alkali metal cyanides under the conditions of the Strecker synthesis.
Abstract: Compounds having the formula ##STR1## in which R is hydrogen, cyano or --COOR.sub.2 ; R.sub.1 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sub.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; and Z is ##STR2## in which A is halogen, B is halogen or hydrogen and Y is nitrogen or --CH--, are herbicides.
Abstract: The invention relates to novel urease inhibited fertilizer compositions containing urea and a urease inhibiting amount of one or more diaminophosphinyl compounds having oxidized sulfur functions, and methods and composition for inhibiting the activity of urease through use of such compounds.
Type:
Grant
Filed:
December 20, 1983
Date of Patent:
December 16, 1986
Assignee:
Allied Corporation
Inventors:
Michael D. Swerdloff, Milorad M. Rogic, Larry L. Hendrickson
Abstract: The invention relates to novel urease inhibited fertilizer compositions containing urea and a urease inhibiting amount of one or more o-diaminophosphinyl derivatives of oximes, and methods and composition for inhibiting the activity of urease through use of such compounds.
Type:
Grant
Filed:
December 20, 1983
Date of Patent:
November 25, 1986
Assignee:
Allied Corporation
Inventors:
Michael D. Swerdloff, Milorad M. Rogic, Larry L. Hendrickson
Abstract: A method is provided for preparing phosphinic acid prodrug intermediates which are useful in preparing phosphinic acid angiotensin-converting enzyme inhibitors which method includes the step of coupling a phosphonous acid or its ester of the structure ##STR1## wherein R is H or lower alkyl and R.sup.1 is lower alkyl, aryl, arylalkyl, cycloalkyl or cycloalkylalkyl, with a conjugated compound of the structure ##STR2## wherein R.sup.2, R.sup.3 and R.sup.4 may be the same or different and each is independently H, lower alkyl or aryl, and Z is --CO.sub.2 R.sup.5 (wherein R.sup.5 is H or lower alkyl), ##STR3## (wherein R.sup.6 is H, lower alkyl aryl or arylalkyl), ##STR4## (wherein R.sup.7 and R.sup.8 are the same or different and are selected from the group consisting of H, lower alkyl, aryl, aryl-lower alkyl, cycloalkyl or cycloalkylalkyl and at least one of R.sup.7 and R.sup.8 is other than H, or R.sup.7 and R.sup.