Additional Benzene Ring Bonded Directly To The Chain Patents (Class 558/402)
  • Patent number: 11622954
    Abstract: Provided are compounds and methods for treating neurodegenerative diseases and conditions, such as multiple sclerosis, using an estrogen receptor-? ligand (ER? ligand).
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: April 11, 2023
    Assignee: The Regents of the University of California
    Inventors: Michael E. Jung, Rhonda R. Voskuhl
  • Publication number: 20140227212
    Abstract: A soluble UVA and/or UVB absorbing chromophore-comprising polymer useful for preparation of a sunscreen lotion has a multiplicity of repeating units where one or more of the repeating units includes at least one UVA and/or UVB absorbing chromophore. The repeating units are those formed from the ring-opening metathesis polymerization (ROMP) of a strained cycloakene, cycloalkadiene, bicycloalkene, or bicycloalkadiene, or where one or more sp3 hybridized carbons of the strained cycloakene, cycloalkadiene, bicycloalkene, or bicycloalkadiene is replaced with a heteroatom. The UVA and/or UVB absorbing chromophore-comprising polymer can be formed from a UVA and/or UVB absorbing chromophore-comprising monomer, which can be homopolymerized or copolymerized by ROMP. Alternately, the UVA and/or UVB absorbing chromophore-comprising polymer can be formed by polymerization of monomers that can subsequently be substituted with UVA and/or UVB absorbing chromophores.
    Type: Application
    Filed: September 10, 2012
    Publication date: August 14, 2014
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Kenneth B. Wagener, Brian S. Aitken, Kenneth B. Sloan, Jason D. Heffley
  • Publication number: 20140173972
    Abstract: A liquid fuel composition containing (a) a gasoline base fuel suitable for use in an internal combustion engine; and (b) one or more organic sunscreen compounds. The liquid fuel composition of the present invention provides benefits in terms of improved acceleration and/or power output of an internal combustion engine fuelled by said fuel as well as an increase in flame speed.
    Type: Application
    Filed: December 19, 2013
    Publication date: June 26, 2014
    Applicant: SHELL OIL COMPANY
    Inventors: Mark Lawrence BREWER, Michael William HOWE
  • Patent number: 8324420
    Abstract: There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: December 4, 2012
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Kenzo Fukuda, Yasuo Kondo, Norio Tanaka, Hideaki Suzuki, Masatoshi Ohnari, Koichi Nishio
  • Publication number: 20120302603
    Abstract: There are provided compounds and methods for the detection and treatment of amyloid deposits and diseases and disorders characterized by amyloid deposits including Alzheimer's disease and related amyloid-based neurodegenerative disorders.
    Type: Application
    Filed: December 10, 2010
    Publication date: November 29, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jerry Yang, Emmanuel A. Theodorakis
  • Publication number: 20110237665
    Abstract: The present invention relates to an agrochemical composition comprising pesticide and UV absorber, and the abovementioned UV absorbers. The invention furthermore relates to the use of the UV absorbers in agrochemical compositions. It moreover relates to a method of controlling phytopathogenic fungi and/or undesirable plant growth and/or undesirable insect or mite infestation and/or of regulating plant growth.
    Type: Application
    Filed: November 30, 2009
    Publication date: September 29, 2011
    Applicant: BASF SE
    Inventors: Andrea Misske, Christian Bittner, Michael Ishaque, Markus Hoffmann, Richard Riggs, Sens Ruediger, Andre Kabat, Sylke Haremza, Douglas D. Anspaugh, David M. Terry
  • Publication number: 20100076205
    Abstract: A dye compound is described, which is expressed by formula (I): wherein A1, A2 and A3 each independently represent a substituted or unsubstituted 1,4-phenylene or 2,5-thiophene group, and B1 and B2 each independently represent a substituted or unsubstituted aryl group. The dye compound is suitably used as a dye sensitizer in a dye sensitized solar cell (DSSC).
    Type: Application
    Filed: May 19, 2009
    Publication date: March 25, 2010
    Applicant: Academia Sinica
    Inventors: Tahsin J. Chow, Yuan-Chieh Chang
  • Patent number: 7649104
    Abstract: There is provided a process for stereoselectively producing E-form of 3-acyloxyacrylonitrile compound (3) or Z-form which comprises reacting 3-oxopropionitrile compound (1) with an acid chloride (2), characterized in that the reaction is conducted with removal of hydrogen chloride, or by using an organic base or an inorganic base, to thereby regulate the stereostructure of the product; a process for producing the compound (1) characterized by reacting acetonitrile compound (5) with an aromatic ester compound (6) by use of an alkali metal alkoxide in a hydrocarbon solvent while removing alcohol formed as a by-product by azeotropic distillation in a separating tank; and a process for isomerizing E-form of 3-acyloxyacrylonitrile compound to Z-form thereof by use of an organic base.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: January 19, 2010
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Kenzo Fukuda, Yasuo Kondo, Norio Tanaka, Hideaki Suzuki, Masatoshi Ohnari, Koichi Nishio
  • Patent number: 7592475
    Abstract: A branched ?-cyanostilbene fluorescent materials with a new structure useful to the organic electroluminescence display (OELD), which includes the organic substance in the state of powder, liquid and film with the stilbene core structure and the terminal branched phenyl structure. The fluorescent materials of the invention exhibits the high luminescent efficiency and is capable of tuning the fluorescent colors of red, green and blue according to the core structure in the molecular, i.e., the structure of stilbene radical, particularly it exhibits the higher luminescent efficiency in the state of solid more than solution.
    Type: Grant
    Filed: June 29, 2002
    Date of Patent: September 22, 2009
    Assignees: Dongwoo Fine-Chem Co., Ltd., Seoul National University Industry Foundation
    Inventors: Sooyoung Park, Soonki Kwon, Byeongkwan An
  • Patent number: 7468446
    Abstract: The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject in need thereof one or more substituted heterocyclic compounds. In particular, the invention relates to methods for preventing or treating cancer or an inflammatory disorder by administering to a subject in need thereof one or more substituted heterocyclic compounds. The present invention further relates to articles of manufacture and kits comprising one or more substituted heterocyclic compounds.
    Type: Grant
    Filed: September 1, 2005
    Date of Patent: December 23, 2008
    Assignee: Celgene Corporation
    Inventors: George W. Muller, Hon-Wah Man
  • Publication number: 20080274304
    Abstract: The present invention concerns functionalized photoreactive compounds of formula (I), that are particularly useful in materials for the alignment of liquid crystals. Due to the adjunction of an electron withdrawing group to specific molecular systems bearing an unsaturation directly attached to two unsaturated ring systems, exceptionally high photosensitivities, excellent alignment properties as well as good mechanical robustness could be achieved in materials comprising said functionalized photoreactive compounds of the invention.
    Type: Application
    Filed: September 15, 2006
    Publication date: November 6, 2008
    Inventors: Mohammed Zoubair Cherkaoui, Peggy Studer, Joachim Reichardt, Hubert Seiberle
  • Publication number: 20080119499
    Abstract: There are provided conjugated systems of formula (I) based on stilbene derivatives serving as improved Donor-Acceptor-Donor compounds and their use in non linear optics including chromophoric optical medium of a 3-dimensional optical memory.
    Type: Application
    Filed: January 12, 2006
    Publication date: May 22, 2008
    Applicant: MEMPILE INC.
    Inventors: Andrew N. Shipway, Nimer Jaber, Moshe Greenwald, Michael Grishko, Ariel Litwak
  • Patent number: 7317066
    Abstract: Liquid crystal polyester derived from phenylene-naphthalene monomers and one or more comonomers display an improved balance of properties, including low melt viscosity, fast cycle time in molding, very low mold shrinkage, high tensile and/or flexural strength, solvent resistance, excellent barrier properties, low water absorption, low thermal expansion coefficient, excellent thermostability, and/or low flammability. The phenylene-naphthalene monomers are The one or more comonomers include 4-hydroxybenzoic acid, 2-hydroxy-6-naphthoic acid, terephthalic acid, isophthalic acid, and derivatives and combinations thereof.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: January 8, 2008
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Brian Benicewicz, Jiping Shao
  • Patent number: 7235587
    Abstract: Diesters that include one or more of a crylene and/or a fluorene moiety, and sunscreen compositions including a mixture of a photoactive compound and one or more of a diester that includes one or more of a crylene and/or a fluorene moiety are described herein. Also disclosed are methods for stabilizing a sunscreen composition, methods of stabilizing a dibenzoylmethane derivative, and methods for protecting human skin from ultraviolet radiation with one or more of a diester that includes one or more of a crylene and/or a fluorene moiety are described herein.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: June 26, 2007
    Assignee: CPH Innovations Corporation
    Inventors: Craig A. Bonda, Anna B. Pavlovic
  • Patent number: 7223988
    Abstract: Embodiments of the present invention are directed toward a photoluminescent article comprising at least one host material and at least one color tunable photoluminescent dye. In certain embodiments, the emission spectrum of the at least one tunable photoluminescent dye may be dependent on the supramolecular architecture of the material. The photoluminescent emission spectrum of the dye is capable of being shifted by subjecting the article to an external stimuli such as, but not limited to, a mechanical deformation, a temperature change, aging of the article, a pressure change, exposure to a chemical compound. In specific embodiments, the color tunable photoluminescent dye is an oligo(phenylene vinylene) compound, such as, but not limited to, 1,4-Bis-(?-cyano-4-methoxystyryl)-benzene, 1,4-bis-(?-cyano-4-methoxystyryl)-2,5-dimethoxybenzene, and 1,4-bis-(?-cyano-4-(2-ethylhexyloxystyryl)-2,5-dimethoxybenzene and 2,5-bis-(?-cyano-4-methoxystyryl)-thiophene.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: May 29, 2007
    Assignee: Case Western Reserve University
    Inventors: Christiane Lowe, Christoph Weder
  • Patent number: 7019030
    Abstract: Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor ?, nuclear factor ?B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3,3-bis-(3,4-dimethoxyphenyl)acrylonitrile.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: March 28, 2006
    Assignee: Celgene Corporation
    Inventors: George W. Muller, Mary Shire
  • Patent number: 6800659
    Abstract: Novel styrylacrylonitrile compounds which are useful in treating a variety of cell proliferative disorders such as cancer are disclosed.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: October 5, 2004
    Assignee: HSC Research and Development Limited Partnership
    Inventors: Chaim M. Roifman, Thomas Grunberger, Olga Rounova, Demin Peter, Nigel Sharfe
  • Patent number: 6596878
    Abstract: The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers characterized by over-activity or inappropriate activity HER2 or EGFR.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: July 22, 2003
    Assignees: Yissum Research & Development Company of the Hebrew University, Sugen, Inc.
    Inventors: Hui Chen, Aviv Gazit, Alexander Levitzki, Klaus Peter Hirth, Elaina Mann, Laura K. Shawver, Jianming Tsai, Peng Cho Tang
  • Patent number: 6465687
    Abstract: Novel thyroid receptor ligands are provided which have the general formula (I) where R1 is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or different and are hydrogen, halogen, alkyl of 1 to 3 carbons or cycloalkyl of 3 to 5 carbons, at least one of R2 and R3 being other than hydrogen; n is an integer from 0 to 4; R4 is an aliphatic hydrocarbon, an aromatic hydrocarbon, carboxylic acid ester thereof, alkenyl carboxylic acid or ester thereof, hydroxy, halogen, cyano, or a phosphonic acid or an ester thereof, or a pharmaceutically acceptible salt thereof. A method for treating diseases associated with metabolism dysfunction or which are dependent on the expression of a T3 regulated gene, such as obesity, hypercholesterolemia, osteoporosis, hypothyroidism, and goiter, is also provided.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: October 15, 2002
    Assignee: Karo Bio AB
    Inventors: Yi-Lin Li, Ye Liu, Asa Hedfors, Johan Malm, Charlotta Mellin, Minsheng Zhang
  • Patent number: 6187944
    Abstract: Acrylonitrile compounds having pesticidal activity of formula (I) and salts thereof. wherein Q is Y is ═C(R4)— or ═N—, R1 is alkyl, haloalkyl, etc., each of R2 and R3 is halogen, alkyl which may be substituted, alkenyl which may be substituted, etc., R4 is hydrogen, halogen, alkyl or haloalkyl, 1 is from 1 to 4, m is from 0 to 5, n is from 0 to 3, q is from 0 to 4, when 1 is 2 or more, a plurality of R2 may be the same or different, when each of m, n and q is 2 or more, a plurality of R3 may be the same or different.
    Type: Grant
    Filed: August 16, 1999
    Date of Patent: February 13, 2001
    Assignee: Ishihara Sangyo Kaisha Ltd.
    Inventors: Toru Koyanagi, Yuji Nakamura, Masayuki Morita, Koji Sugimoto, Tsuyoshi Ikeda, Munekazu Ogawa
  • Patent number: 5955000
    Abstract: This invention describes compounds of formula (I) ##STR1## wherein R is C.sub.1-16 alkyl or alkoxy; X is selected from F and Cl and indicates that one or more of the phenyl rings may be laterally substituted; x is selected from 0-3; A and B are independently selected from CO.sub.2, OCO, .tbd.C and single bond; R.sub.1 and R.sub.2 are independently selected from H and C.sub.1-16 alkyl provided that R.sub.1 and R.sub.2 are different; n is 0 or 1 provided that if n is zero then B is single bond. These compounds may be used as dopants suitable for use in ferroelectric liquid crystal mixtures.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: September 21, 1999
    Assignee: The Secretary of State for Defence
    Inventors: Benjamin Ross Carrick, John William Goodby, Kenneth Johnson Toyne, Michael Hird, Damien Gerard McDonnell
  • Patent number: 5935563
    Abstract: A compound of the formula I ##STR1## where R.sup.1 is i-propyl, i-butyl or t-butyl,R.sup.2 is alkyl with 6-14 carbon atoms, ##STR2## with R.sup.3 =H or C.sub.1 -C.sub.4 -alkyl and m, n=0 or 1.
    Type: Grant
    Filed: April 15, 1998
    Date of Patent: August 10, 1999
    Assignee: BASF Aktiengesellschaft
    Inventor: Beate Trentmann
  • Patent number: 5929117
    Abstract: Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor .alpha., nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3,3-bis-(3,4-dimethoxyphenyl)acrylonitrile.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: July 27, 1999
    Assignee: Celgene Corporation
    Inventors: George W. Muller, Mary Shire
  • Patent number: 5917080
    Abstract: A process for preparing 2-cyano-3,3-diarylacrylic esters of the general formula I ##STR1## where R.sup.1 and R.sup.2 are hydrogen, C.sub.1 -C.sub.12 -alkyl groups, C.sub.- C.sub.12 -alkoxy groups or di(C.sub.1 -C.sub.4 -alkyl)amino groups and R.sup.3 is a C.sub.4 -C.sub.18 -alkyl group which can be interrupted by ether-functional oxygen atoms, by reacting a benzophenone imine of the general formula II ##STR2## with a cyanoacetic ester of the general formula III ##STR3## wherein the reaction is carried out at from 20 to 60.degree. C. and, during this, the liberated ammonia is continuously removed from the reaction mixture with the aid of a stream of gas or by reducing the pressure to from 900 to 100 mbar.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: June 29, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Holderbaum, Karl Beck, Alexander Aumuller, Tom Witzel, Guido Voit
  • Patent number: 5892096
    Abstract: Mid-UV dyes enabling ultra thin antireflection coatings for multi-layer i-line photoetching are produced from bichalcones; bis-a-cyanoacrylates/bis-cyanoacrylamides; and 1.4 divinylbenzenes. The dyes are nonsubliminal and differentially insoluble in standard photoresist solvents.
    Type: Grant
    Filed: February 8, 1996
    Date of Patent: April 6, 1999
    Assignee: Brewer Science, Inc.
    Inventors: Jim D. Meador, Xie Shao, Vandana Krishnamurthy, Earnest C. Murphy, Tony D. Flaim, Terry Lowell Brewer
  • Patent number: 5830441
    Abstract: A photostable UV absorbent with maximum absorption above 340 nm having the formula: ##STR1## wherein R is --CO(R.sub.2) or phenyl optionally substituted with lower alkyl and/or lower alkoxy;R.sub.2 is --alkyl, --O(C.sub.2+ alkyl), ##STR2## n has a value of from 2 to 8; S and T each independently are hydroxy, lower alkyl, lower alkoxy or, when R.sub.2 is alkyl or alkoxy, S can also be phenyl and when R.sub.2 is alkoxy, T is alkoxy, or S+T taken with the phenyl ring form a naphthyl radical or a fused benzodioxol-5-yl heterocyclic radical;k+l has a value of from 0 to 3 with the proviso that, when R.sub.2 is--O(alkyl), T is --O(lower alkyl) and the value of l is 2 or 3;R.sub.3 is hydrogen or lower alkylene;R.sub.4, R.sub.5, and R.sub.6 are each independently C.sub.1 to C.sub.18 alkyl or one of R.sub.4, R.sub.5 and R.sub.6 can be phenyl andA is an anion.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: November 3, 1998
    Assignee: ISP Investments Inc.
    Inventors: Chenjie Wang, Ratan K. Chaudhuri, Janusz Jachowicz, Bruce C. Locke, Frank M. Miksza
  • Patent number: 5821380
    Abstract: Novel 2-cyanoacrylic esters I ##STR1## where the radicals have the following meanings: R.sup.1 and R.sup.2 are each hydrogen or a radical having an iso- or heterocyclic ring system with at least one iso- or heteroaromatic nucleus, and at least one of the radicals R.sup.1 or R.sup.2 must be different from hydrogen,n is from 2 to 10, andX is, when n=2, a radical of the formula II ##STR2## where m is from 2 to 8, and X is, when n>2, the radical of an n-hydric aliphatic or cycloaliphatic polyol having 3-20 carbon atoms, it also being possible for a cycloaliphatic radical to contain 1 or 2 hetero atoms, and for an aliphatic radical to be interrupted by up to 8 non-adjacent oxygen atoms, sulfur atoms, imino or C.sub.1 -C.sub.4 -alkylimino groups, are used as light stabilizers.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: October 13, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Holderbaum, Alexander Aumuller, Hubert Trauth, Guido Voit, Karin Sperling, Alfred Krause
  • Patent number: 5674906
    Abstract: Stilbene compounds of the following formula (I) or their pharmaceutically acceptable salts are effective as carcinostatics and of low toxicity: ##STR1## wherein X represents a hydrogen atom or a nitrile group, and Y represents an amino acid acyl group.
    Type: Grant
    Filed: March 7, 1996
    Date of Patent: October 7, 1997
    Assignee: Ajinomoto Co., Inc.
    Inventors: Toshihiro Hatanaka, Koji Ohsumi, Takashi Tsuji, Yukio Nihei, Ryusuke Nakagawa, Kazuo Ohishi
  • Patent number: 5631405
    Abstract: The present invention relates to a method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized.This method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3-substituted-2-propanol chemical intermediate.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 20, 1997
    Assignee: Pharm-Eco Laboratories, Incorporated
    Inventors: Biman Pal, Siya Ram, Bing Cai, Yesh P. Sachdeva, Jaechul Shim, Salah A. Zahr, Emile Al-Farhan, Richard L. Gabriel
  • Patent number: 5589506
    Abstract: The present invention relates to a novel compound having a 12-lipoxygenase inhibitory effect, of the general formula (I), a precursor thereof, and a medicine containing the same, ##STR1## wherein R.sup.1 represents a hydrogen atom or a hydroxy group; one of R.sup.2 and R.sup.3 represents a hydrogen atom, while the other cyano group ; and Ar is a group represented by the following general formula (a), (b) or (c), ##STR2## wherein R.sup.4 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a thrifluoromethyl group or a cyano group.
    Type: Grant
    Filed: December 30, 1994
    Date of Patent: December 31, 1996
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Koichi Hashimoto, Akio Yamada, Hirokazu Hamano, Shigehiro Mori, Hisako Moriuchi
  • Patent number: 5525632
    Abstract: A stilbene derivative of the following general formula (I) or a pharmaceutically acceptable acid addition salt thereof have low toxicity, but are water soluble and effective as carcinostatics: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent an alkyl group having 1 to 3 carbon atoms; X represents a hydrogen atom or a nitrile group; Y represents an alkyloxy group having 1 to 3 carbon atoms, an alkyl group having 1 to 6 carbon atoms or a halogen atom.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: June 11, 1996
    Assignee: Ajinomoto Co., Ltd.
    Inventors: Koji Obsumi, Takashi Tsuji, Yoshihiro Morinaga, Kazuo Ohishi
  • Patent number: 5442086
    Abstract: Disclosed are certain poly-methine compounds having the formula ##STR1## wherein each R.sup.1 is independently selected from cyano; carboxy; alkenyloxycarbonyl; an unsubstituted or substituted alkoxycarbonyl, cycloalkoxycarbonyl or aryloxycarbonyl radical; an unsubstituted or substituted, carbocyclic or heterocyclic aryl radical; an unsubstituted or substituted alkanoyl, cycloalkanoyl or aroyl radical; an unsubstituted or substituted carbamoyl radical; or an unsubstituted or substituted alkylsulfonyl, cycloalkylsulfonyl or arylsulfonyl radical; each R.sup.2 is independently selected from cyano or an unsubstituted or substituted alkoxycarbonyl, cycloalkoxycarbonyl or aryloxycarbonyl radical; each A is independently selected from an unsubstituted or substituted 1,2-phenylene or 1,2-naphthylene radical; each Z is independently selected from --0-- or --S--; and L is an organic linking group bonded by non-oxo carbon atoms to each Z atom.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: August 15, 1995
    Assignee: Eastman Chemical Company
    Inventors: James J. Krutak, Max A. Weaver, Clarence A. Coates, Jr., Samuel D. Hilbert, Terry A. Oldfield, William W. Parham, Wayne P. Pruett
  • Patent number: 5414121
    Abstract: Adducts containing mesogenic or rodlike moieties are prepared by reacting (1) at least one compound containing an average of more than one vicinal epoxide group per molecule with (2) at least one compound containing an average of more than one reactive hydrogen atom per molecule; with the proviso that at least one member of components (1) and (2) contains a mesogenic or rodlike moiety. These compounds are useful as curing agents for epoxy resins.
    Type: Grant
    Filed: September 8, 1993
    Date of Patent: May 9, 1995
    Assignee: The Dow Chemical Company
    Inventors: Robert E. Hefner, Jr., Jimmy D. Earls
  • Patent number: 5382693
    Abstract: bis(Aminophenoxy)-alpha-substituted stilbenes are prepared by reacting a dihydroxy-alpha-substituted stilbene with a halonitrobenzene in the presence of a basic acting substance such as potassium carbonate and hydrogenating the resulting bis(nitrophenoxy)-alpha-substituted stilbene to convert the nitro groups to amino groups. These compounds are useful as curing agents for epoxy resins.
    Type: Grant
    Filed: October 27, 1993
    Date of Patent: January 17, 1995
    Assignee: The Dow Chemical Company
    Inventors: V. Rao Durvasula, Robert E. Hefner, Jr., Jimmy D. Earls
  • Patent number: 5321112
    Abstract: The invention provides hydroxy-functional cyanoacrylate ultraviolet radiation absorbing compounds. The radiation absorbing compounds can be incorporated into step growth polymers such as polyurethanes, polyesters, and polycarbonates. The invention also provides such polymers having the radiation compound incorporated therein and articles prepared therefrom.
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: June 14, 1994
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: David B. Olson
  • Patent number: 5302740
    Abstract: Disclosed are certain poly-methine compounds having the formula ##STR1## wherein each R.sup.1 is independently selected from cyano; carboxy; alkenyloxycarbonyl; an unsubstituted or substituted alkoxycarbonyl, cycloalkoxycarbonyl or aryloxycarbonyl radical; an unsubstituted or substituted, carbocyclic or heterocyclic aryl radical; an unsubstituted or substituted alkanoyl, cycloalkanoyl or aroyl radical; an unsubstituted or substituted carbamoyl radical; or an unsubstituted or substituted alkylsulfonyl, cycloalkylsulfonyl or arylsulfonyl radical; each R.sup.2 is independently selected from cyano or an unsubstituted or substituted alkoxycarbonyl, cycloalkoxycarbonyl or aryloxycarbonyl radical; each A is independently selected from an unsubstituted or substituted 1,2-phenylene or 1,2-naphthylene radical; each Z is independently selected from --O-- or --S--; and L is an organic linking group bonded by non-oxo carbon atoms to each Z atom.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: April 12, 1994
    Assignee: Eastman Kodak Company
    Inventors: James J. Krutak, Max A. Weaver, Clarence A. Coates, Jr., Samuel D. Hilbert, Terry A. Oldfield, William W. Parham, Wayne P. Pruett
  • Patent number: 5218136
    Abstract: A styryl compound of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.11 are the same or different and a hydrogen atom, an optionally substituted alkyl, alkenyl or aralkyl group or R.sub.1 and R.sub.2 may form a ring together with the nitrogen atom to which they are bonded, which ring may include at least one hetero atom in addition to said nitrogen atom; R.sub.10 is an optionally substituted alkylene group; R.sub.3 is --OH, --OCOR.sub.5 or --OSi(R.sub.5).sub.3 in which R.sup.5 is an alkyl group; R.sub.12 and R.sub.13 are independently a hydrogen atom, an optionally substituted lower alkyl or alkoxy group, an amide group or a halogen atom; X, Y, W and Z are the same or different and an electron attracting group, and n is a number of 2-15, which is suitable as a light absorber in a photoresist composition.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: June 8, 1993
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Takanori Yamamoto, Shinji Konishi, Ryotaro Hanawa, Akirhiro Furuta, Takeshi Hioki, Jun Tomioka
  • Patent number: 5214186
    Abstract: A process for the preparation of arylidene dyes comprises the reaction of an aromatic amine with an enolate salt of a formylated active methylene compound in the presence of a sulfonyl halide compound. An enol sulfonate is postulated as a reactive intermediate in the reaction. The process gives high yields of products under mild reaction conditions and allows the use of aromatic groups containing substituents such as hydroxy that lead to side reactions and low product yields with previously known methods for making arylidene dyes.
    Type: Grant
    Filed: December 3, 1991
    Date of Patent: May 25, 1993
    Assignee: Eastman Kodak Company
    Inventor: Leslie Shuttleworth
  • Patent number: 5162405
    Abstract: The present invention comprises novel single-functional and mixtures of multi-functional oligomeric performance additive compounds having one or more components of Structure A R1 ? ? ##STR1## (The definitions of R, Z1, Z2, Z3, A1, A2, A3 and y are given in the Summary Section), their uses and polymeric compounds and compositions containing them which have enhanced oxidative stabilities, enhanced ultraviolet (UV) and light stabilites and/or enhanced flame retardance. An example is the bis sulfonic acid bispotassium salt reaction product from an oligomeric caprolactone diol (TONE.RTM. 260), 2-sulfobenzoic acid anhydride and potassium carbonate, and use of this product, at levels up to about 3.0%, in a general purpose bisphenol A polycarbonate resin, to enhance the fire resistance or flame retardance of the polycarbonate resin.
    Type: Grant
    Filed: March 22, 1991
    Date of Patent: November 10, 1992
    Assignee: ELF Atochem North America, Inc.
    Inventors: Ronald E. MacLeay, Jose Sanchez, Daryl L. Stein
  • Patent number: 5103010
    Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.
    Type: Grant
    Filed: November 13, 1990
    Date of Patent: April 7, 1992
    Assignee: Eisai Co., Ltd.
    Inventors: Youji Yamagishi, Kozo Akasaka, Takeshi Suzuki, Mitsuaki Miyamoto, Kouji Nakamoto, Kazuo Okano, Shinya Abe, Hironori Ikuta, Kenji Hayashi, Hiroyuki Yoshimura, Tohru Fujimori, Koukichi Harada, Isao Yamatsu
  • Patent number: 5075487
    Abstract: A fluorene derivative useful as an electron transport material is disclosed, which is represented by formula (I) ##STR1## wherein R.sub.1 represents a hydrogen atom or a phenyl group, R.sub.2 represents a hydrogen atom, a nitro group, or an alkoxycarbonyl group, and R.sub.3 and R.sub.4 each represents a hydrogen atom or an alkyl group.
    Type: Grant
    Filed: April 10, 1990
    Date of Patent: December 24, 1991
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Yutaka Akasaki, Katsuhiro Sato, Katsumi Nukada
  • Patent number: 5047571
    Abstract: The preparation of 2-cyano-3,3-diarylacrylates I ##STR1## (in which Ar.sup.1 and Ar.sup.2 are aromatic radicals and R is an aliphatic radical having from 3 to 30 carbon atoms) by reacting a 2-cyano-3,3-diarylacrylate II ##STR2## (in which R.sup.1 is methyl or ethyl) with an alcohol IIIR--OH (III)in the presence of a basic catalyst with removal of the alcohol R.sup.1 -OH formed.The esters of formula I are valuable UV absorbing agents for, say, plastics materials.
    Type: Grant
    Filed: April 13, 1990
    Date of Patent: September 10, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Spang, Peter Neumann
  • Patent number: 5028730
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl;A is ##STR2## and R.sup.5 is hydrogen, a hydrolyzable ester group or a cation to form a non-toxic pharmaceutically acceptable salt,are novel antihypercholesterolemic agents which inhibit cholesterol biosynthesis. Intermediates and processes for their preparation are disclosed.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: July 2, 1991
    Assignee: Bristol-Myers Company
    Inventors: Sing-Yuen Sit, John J. Wright
  • Patent number: 5011969
    Abstract: Fluorene derivatives represented by the general formula (I): ##STR1## wherein R represents an alkyl group having 1 to 8 carbon atoms, a phenyl group of a C.sub.1 -C.sub.8 alkyl-substituted phenyl group, and a process for preparation thereof. These fluorene derivatives are synthesized by reacting fluorenone derivatives represented by the general formula (II): ##STR2## wherein R is the same as defined above, with malonitrile.
    Type: Grant
    Filed: November 16, 1989
    Date of Patent: April 30, 1991
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Yutaka Akasaki, Katsumi Nukada, Katsuhiro Sato
  • Patent number: 5008431
    Abstract: Benzophenone derivatives which are useful in electrophotographic light-sensitive material represented by formula (I): ##STR1## wherein A represents the structural formula (a), (b) or (c): ##STR2## and R represents an alkyl group having 1 to 8 carbon atoms or a nitro group, and a process for preparation thereof. These benzophenone derivatives can be synthesized by reacting compounds represented by formula (II): ##STR3## wherein A and R are the same as defined above, with malonitrile.
    Type: Grant
    Filed: November 15, 1989
    Date of Patent: April 16, 1991
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Yutaka Akasaki, Katsumi Nukada, Katsuhiro Sato
  • Patent number: 4981991
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl;A is ##STR2## R.sup.5 is hydrogen, a hydrolyzable ester group or a cation to a form a non-toxic pharmaceutically acceptable salt,are novel antihypercholesterolemic agents which inhibit cholesterol biosynthesis. Intermediates and processes for their preparation are disclosed.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: January 1, 1991
    Assignee: Bristol-Myers Company
    Inventors: Sing-Yuen Sit, John J. Wright
  • Patent number: 4978767
    Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(.dbd.
    Type: Grant
    Filed: June 9, 1989
    Date of Patent: December 18, 1990
    Assignee: Eisai Co., Ltd.
    Inventors: Youji Yamagishi, Kozo Akasaka, Takeshi Suzuki, Mitsuaki Miyamoto, Kouji Nakamoto, Kazuo Okano, Shinya Abe, Hironori Ikuta, Kenji Hayashi, Hiroyuki Yoshimura, Tohru Fujimori, Koukichi Harada, Isao Yamatsu
  • Patent number: 4958043
    Abstract: A composition useful for incorporation into polymer compositions employed for food packaging or the like comprising a bis- or tris-methine compound having the structural formula ##STR1## wherein A is selected from the radicals ##STR2## wherein R' and R" are each selected from chlorine, bromine, fluorine, alkyl, alkoxy, aryl, aryloxy and arylthio;each n is independently 0, 1, 2;R.sub.1 is selected from a large variety of radicals such as cycloalkyl, phenyl, and straight or branched alkyl which may be substituted;R.sub.2 is alkylene or the like;R.sub.3, R.sub.4, and R.sub.5 are each selected from hydrogen and alkyl; andP and Q and P.sup.1 and Q.sup.1 are selected from cyano, carbalkoxy, carbaryloxy, carbaralkyloxy, or the like.The invention compositions are especially useful in combination with molding or fiber-grade condensation polymer; most preferably such polymer having copolymerized therein a total of from 1.
    Type: Grant
    Filed: April 18, 1988
    Date of Patent: September 18, 1990
    Assignee: Eastman Kodak Company
    Inventors: Max A. Weaver, Wayne P. Pruett, Samuel D. Hilbert
  • Patent number: 4927944
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl;A is ##STR2## and R.sup.5 is hydrogen, a hydrolyzable ester group or a cation to form a non-toxic pharmaceutically acceptable salt,are novel antihypercholesterolemic agents which inhibit cholesterol biosynthesis. Intermediates and processes for their preparation are disclosed.
    Type: Grant
    Filed: August 25, 1988
    Date of Patent: May 22, 1990
    Assignee: Bristol-Myers Company
    Inventors: Sing-Yuen Sit, John J. Wright
  • Patent number: 4886834
    Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(C.dbd.
    Type: Grant
    Filed: March 11, 1987
    Date of Patent: December 12, 1989
    Assignee: Eisai Co., Ltd.
    Inventors: Youji Yamagishi, Kozo Akasaka, Takeshi Suzuki, Mitsuaki Miyamoto, Kouji Nakamoto, Kazuo Okano, Shinya Abe, Hironori Ikuta, Kenji Hayashi, Hiroyuki Yoshimura, Tohru Fujimori, Koukichi Harada, Isao Yamatsu