Sulfoxy In Acid Moiety Patents (Class 560/11)
  • Patent number: 4501704
    Abstract: A process for the preparation of tetrasubstituted novel compounds of the formula ##STR1## wherein Y' is selected from the group consisting of --CN and --COOR, R is alkyl of 1 to 6 carbon atoms and R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are individually selected from alkyl of 1 to 4 carbon atoms or R.sub.1 and R.sub.2 or R.sub.3 and R.sub.4 together with the carbon atoms to which they are attached form a carbon homocycle of 3 to 6 carbon atoms with the 2 substituents not forming the ring being alkyl of 1 to 4 carbon atoms or R.sub.1 and R.sub.2 on the one hand and R.sub.3 and R.sub.4 on the other together with the carbon atom to which they are attached form a carbon homocycle of 3 to 6 carbon atoms and Z is an aromatic group which are useful intermediates for the preparation of insecticidal esters.
    Type: Grant
    Filed: March 28, 1983
    Date of Patent: February 26, 1985
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Tessier, Jean-Pierre Demoute
  • Patent number: 4486223
    Abstract: A compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkoxy group, X and Y, being the same or different, are each a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a carboxy(lower)alkoxy group or a lower alkoxycarbonyl(lower)alkoxy group and Z is a hydrogen atom or a halogen atom, which is useful as a herbicide.
    Type: Grant
    Filed: November 17, 1982
    Date of Patent: December 4, 1984
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hiroyuki Konishi, Naganori Hino, Hiroshi Matsumoto, Ryo Yoshida
  • Patent number: 4483992
    Abstract: 3-Alkylthio (arylthio)-4-substituted phenoxy alkanoic acid esters, derivatives thereof, and the use thereof for the control of weeds.
    Type: Grant
    Filed: August 10, 1982
    Date of Patent: November 20, 1984
    Assignee: Zoecon Corporation
    Inventors: Gustave K. Kohn, Joe T. Bamberg
  • Patent number: 4483969
    Abstract: This invention relates to new emulsifiable polyester waxes which are linear polyester waxes which are end capped with polyfunctional organic anhydrides. The emulsifiable polyester waxes are generally amorphous or semicrystalline solids with melting points less than about 100.degree. C. These polyester waxes are useful in preparing clear emulsions which can be applied to surfaces to form protective and decorative films or coatings.
    Type: Grant
    Filed: June 30, 1983
    Date of Patent: November 20, 1984
    Assignee: Eastman Kodak Company
    Inventors: Frederick B. Joyner, Jimmy R. Trotter, Richard L. McConnell
  • Patent number: 4482733
    Abstract: An improved process for preparing diaryl esters of dicarboxylic acids is disclosed, in which the esterification reaction is optimized by gradually increasing the temperature at which the reaction is being conducted according to a predetermined pattern. The temperature increase should be a function of the degree of esterification. The diaryl esters so prepared are useful in making linear polyesters.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: November 13, 1984
    Assignee: Occidental Chemical Corporation
    Inventor: Gautam R. Ranade
  • Patent number: 4482732
    Abstract: An improved process for preparing diaryl esters of dicarboxylic acids is disclosed, in which the esterification reaction is optimized by removing water and other by-products of the reaction according to a predetermined pattern. The removal of water and other by-products of the esterification reaction is most easily carried out by a distillation means, and the rate of removal is controlled by varying the reflux ratio in the distillation means during the course of the esterification reaction. The diaryl esters so prepared are useful in making linear polyesters.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: November 13, 1984
    Assignee: Occidental Chemical Corporation
    Inventor: Gautam R. Ranade
  • Patent number: 4472466
    Abstract: Fluorinated esters based on multi-ring anhydride systems are disclosed which have excellent anti-soiling properties, durability and resistance to laundering. The compounds are represented by the formula ##STR1## wherein n is 2 or 3, Q is a linking group such as --CO--, --O--, or (C.sub.a H.sub.2a+2-n --(O.sub.2 C).sub.n, R.sub.f is a fluorinated radical, and R is derived from an epoxide such as ethylene oxide or epichlorohydrin. Also disclosed are polyester and nylon fibers having these compounds incorporated therein, and a process for producing such soil-repellent fibers.
    Type: Grant
    Filed: March 8, 1982
    Date of Patent: September 18, 1984
    Assignee: American Hoechst Corporation
    Inventors: Michael G. Kelly, Willi R. Steckelberg
  • Patent number: 4465690
    Abstract: Compounds of the formula: ##STR1## wherein X is hydrogen, halogen, lower alkyl, lower alkoxy, nitro, cyano, lower alkylthio, trihalomethyl or amino; Y is halogen; z is 0, 1 or 2; and R is lower alkyl, lower alkenyl or lower alkynyl, all optionally substituted with 1 to 3 halogen atoms, are fungicidal or intermediates in the preparation of fungicides.
    Type: Grant
    Filed: August 26, 1982
    Date of Patent: August 14, 1984
    Assignee: Chevron Research Company
    Inventor: Edward I. Aoyagi
  • Patent number: 4460400
    Abstract: There are described novel dihydropyrones of the formula I ##STR1## wherein R.sub.1 and R.sub.2 independently of one another are each a C.sub.1 -C.sub.4 -alkyl group, or one of the two substituents is also hydrogen, or R.sub.1 and R.sub.2 jointly form a C.sub.2 -C.sub.6 -alkylene bridge, R.sub.3 is C.sub.1 -C.sub.4 -alkoxy, C.sub.2 -C.sub.6 -alkenyloxy, C.sub.2 -C.sub.4 -alkynyloxy, C.sub.1 -C.sub.4 -haloalkoxy, C.sub.3 -C.sub.5 -alkoxyalkoxy or hydroxyl, and X, Y and Z independently of one another are each hydrogen, halogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, C.sub.1 -C.sub.4 -haloalkyl, C.sub.1 -C.sub.4 -haloalkoxy, --S(O).sub.n -C.sub.1 -C.sub.4 -alkyl, --S(O).sub.n -C.sub.1 -C.sub.4 -haloalkyl, where n is 0, 1 or 2, or they are each C(O)OR.sub.4, where R.sub.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, or they are each NO.sub.2, CN or NR.sub.5 R.sub.6, where R.sub.5 and R.sub.6 independently of one another are each hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: July 17, 1984
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans Tobler, Werner Fory
  • Patent number: 4451664
    Abstract: An improved process for preparing diaryl esters of a monohydroxy aromatic compound with dicarboxylic acids is disclosed, in which the esterification reaction is optimized by continuously removing water and/or other by-products of the reaction from the reactor, while supplying to the reactor a make-up amount of the monohydroxy aromatic compound containing no more than about 100 ppm of water. The make-up stream may be obtained by stripping the by-product stream of water and other by-products of the reaction.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: May 29, 1984
    Assignee: Occidental Chemical Corporation
    Inventor: Gautam R. Ranade
  • Patent number: 4446077
    Abstract: Novel 2-vinyl- and 2-ethyl-cyclopropyl sulfones are provided. In addition to the ethyl or vinyl group at the 2-position of the ring, the compounds of this invention are disubstituted at the 1-position with a sulfonyl group and an acyl, nitrile or nitrile-derived radical. The sulfones of this invention are useful chemical intermediates from which a wide variety of pesticidal, herbicidal or biologically active compounds can be prepared and are useful monomers for anionic or radical polymerizations.
    Type: Grant
    Filed: February 4, 1982
    Date of Patent: May 1, 1984
    Assignee: National Distillers and Chemical Corporation
    Inventors: Richard G. Fayter, Jr., Allen L. Hall
  • Patent number: 4444682
    Abstract: A method for sulfating a hydroxy amino acid or a residue of such an amino acid in a peptide by reaction with a reagent which is a tertiaryammonium salt of acetylsulfuric acid having the formula:[CH.sub.3 COOSO.sub.3 ].sup.- [R].sup.+wherein R is triethylamine, ethyldiisopropylamine, pyridine, 4-methylmorpholine or 4-N,N-dimethylaminopyridine. The .alpha.-amino group and any other labile side chains present may be protected or may be left unprotected at the time the sulfation takes place.
    Type: Grant
    Filed: November 4, 1982
    Date of Patent: April 24, 1984
    Assignee: The Salk Institute for Biological Studies
    Inventors: Jean E. F. Rivier, Botond Penke
  • Patent number: 4422870
    Abstract: 2-Aryl-1, 3-cyclohexanedione enol ester compounds exhibit outstanding miticidal,mite ovicidal and herbicidal activity.
    Type: Grant
    Filed: March 28, 1977
    Date of Patent: December 27, 1983
    Assignee: Union Carbide Corporation
    Inventor: Thomas N. Wheeler
  • Patent number: 4423064
    Abstract: This invention relates to novel ester compounds derived from alkynoic acids and to their preparation. This invention is also directed to insecticidal and miticidal compositions comprising an acceptable carrier and an insecticidally or miticidally effective amount of a novel ester compound of this invention as well as a method of controlling pests by subjecting them to an insecticidally or miticidally effective amount of a novel ester compound of this invention.
    Type: Grant
    Filed: June 29, 1981
    Date of Patent: December 27, 1983
    Assignee: Union Carbide Corporation
    Inventor: Thomas N. Wheeler
  • Patent number: 4406909
    Abstract: A fungicidally active 4-substituted-1-azolyl-1-phenoxy-3,3-dimethyl-butan-2-one or -ol of the formula ##STR1## in which A is a nitrogen atom or CH,B is --CO-- or CH(OH),R is cyano or X--R.sup.1,R.sup.1 is alkyl, optionally substituted aryl or optionally substituted aralkyl,X is oxygen, sulphur, SO or SO.sub.2,Z each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, alkylsulphonyl, nitro, cyano, alkoxycarbonyl or optionally substituted phenyl, andn is 0, 1, 2 or 3,or an addition product thereof with a physiologically acceptable acid or with a metal salt. Intermediates therefor of the formula ##STR2## are also new.
    Type: Grant
    Filed: May 19, 1981
    Date of Patent: September 27, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Hans-Ludwig Elbe, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4401601
    Abstract: A process for the preparation of tetrasubstituted cyclopropane compounds of the formula ##STR1## wherein Y is selected from the group consisting of --CN and --COOR, R is selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms and R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are individually selected from alkyl of 1 to 4 carbon atoms or R.sub.1 and R.sub.2 or R.sub.3 and R.sub.4 together with the carbon atoms to which they are attached form a carbon homocycle of 3 to 6 carbon atoms with the 2 substituents not forming the ring being alkyl of 1 to 4 carbon atoms or R.sub.1 and R.sub.2 on the one hand and R.sub.3 and R.sub.4 on the other together with the carbon atom to which they are attached form a carbon homocycle of 3 to 6 carbon atoms which are useful intermediates for the preparation of insecticidal esters and novel intermediates.
    Type: Grant
    Filed: March 23, 1981
    Date of Patent: August 30, 1983
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Tessier, Jean-Pierre Demoute
  • Patent number: 4395566
    Abstract: An improved process for exterifying carboxyaromatics is disclosed wherein an anhydride of a carboxyaromatic, such as pyromellitic dianhydride, is reacted with a fluorinated alcohol and an epoxide to give a mixed ester capable of imparting oil and/or water repellency to textiles. The improvement comprises utilizing the epoxide as the reaction medium to reduce reaction times and waste water treatment requirements.
    Type: Grant
    Filed: March 8, 1982
    Date of Patent: July 26, 1983
    Assignee: American Hoechst Corporation
    Inventors: James H. Covill, Michael G. Kelly, Thomas F. Leahy
  • Patent number: 4390476
    Abstract: Phosphonium compounds of the formula(R).sub.3 P.sup..sym. --CH.sub.2 --X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar.in which R is preferably alkyl having 1 to 4 C atoms, cyclohexyl or phenyl, R.sub.1 is a substituted or unsubstituted aromatic radical, especially a phenyl radical, X is phenylene, 4,4'-biphenylene or 1,4- or 2,6-naphthylene and Y.sup..crclbar. is SO.sub.3.sup..crclbar., SO.sub.2.sup..crclbar. or COO.sup..crclbar., a process for their preparation and a process for the preparation of asymetrically substituted fluorescent brightening agents of the formulaZ--CH.dbd.CH--X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar. M.sup..sym.in which R.sub.1, X and Y.sup..crclbar. are as defined above, M.sup..sym. is a cation and Z is preferably a substituted or unsubstituted phenyl or 2-phenyl-triazol-4-yl radical, by reacting a bis-phosphonium compound of the formula ##STR1## in which Q.sup..crclbar. is an anion, with an aldehyde of the formula M.sup..sym. Y.sup..crclbar. --R.sub.
    Type: Grant
    Filed: November 5, 1981
    Date of Patent: June 28, 1983
    Assignee: Ciba-Geigy Corporation
    Inventor: Michael Marky
  • Patent number: 4388475
    Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: June 14, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Raymond A. Firestone
  • Patent number: 4382037
    Abstract: Novel 3-formyl-4-methyl-pentanoic acid derivatives of the formula ##STR1## wherein Y is an aromatic group, R.sub.2 and R.sub.3 are individually alkyl of 1 to 4 carbon atoms or taken together with the carbon atom to which they are attached form a carbon homocycle of 3 to 6 carbon atoms, the Rs are alkyl of 1 to 6 carbon atoms or together form a polymethylene of 2 to 3 carbon atoms and Z' is selected from the group consisting of --COOH and Z and Z is selected from the group consisting of cyano and --COOR.sub.1 wherein R.sub.1 is alkyl of 1 to 6 carbon atoms and their preparation which are useful for the preparation of 3-formyl-4-R.sub.2 R.sub.3 -but-3-ene-1-oic acid which is an intermediate for the preparation of a compound of the formula ##STR2## wherein R.sub.4 is hydrogen or the remainder of an alcohol of the formula R.sub.1 OH by the process of copending, commonly assigned U.S. patent application No. 153,338 filed May 27, 1980.
    Type: Grant
    Filed: March 23, 1981
    Date of Patent: May 3, 1983
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Tessier, Jean-Pierre Demoute
  • Patent number: 4374662
    Abstract: A compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkoxy group and X and Y are, the same or different, each a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group, a carboxy(lower)alkoxy group or a lower alkoxycarbonyl(lower)alkoxy group, which is useful as a herbicide.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: February 22, 1983
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hiroyuki Konishi, Naganori Hino, Hiroshi Matsumoto, Ryo Yoshida
  • Patent number: 4351950
    Abstract: Novel substituted arylene compounds and methods for their preparation and use are disclosed. These new compounds are useful as anti-arteriosclerotic agents.
    Type: Grant
    Filed: January 2, 1980
    Date of Patent: September 28, 1982
    Assignee: Warner-Lambert Company
    Inventor: Ila Sircar
  • Patent number: 4335249
    Abstract: Diphenyl ethers of the formula ##STR1## wherein R.sup.1 is hydrogen or halogen,R.sup.2 is hydrogen, halogen, or cyano,R is ##STR2## wherein R.sup.3 is hydrogen, halogen, nitro, alkyl, or alkoxy,R.sup.4 is a divalent alkylene radical, andR.sup.5 is cyano or --COR.sup.6, wherein R.sup.6 is alkoxy, hydroxy or salt thereof, allyloxy, alkoxyalkoxy, amino, alkyl or dialkyl amino, aminoalkoxy, or alkyl or dialkylaminoalkoxy,and diphenyl sulfides, sulfoxides, and sulfones of the formula ##STR3## wherein R.sup.8 is hydrogen, halogen, cyano, nitro, alkyl, alkoxy, or trifluoromethyl,R.sup.2 is hydrogen, halogen or cyano,X is sulfur, sulfinyl, or sulfonyl, andR is as defined above,and compositions containing these compounds exhibit herbicidal activity.
    Type: Grant
    Filed: July 30, 1976
    Date of Patent: June 15, 1982
    Assignee: Rohm and Haas Company
    Inventors: Wayne O. Johnson, Roy Y. Yih
  • Patent number: 4335055
    Abstract: Compounds of the formula I ##STR1## in which Z, Z.sub.1, R, m and p are as defined in patent claim 1, can be obtained in a simple and economical manner by a novel process wherein a halide of the formula II ##STR2## is reacted with a substituted or unsubstituted vinylbenzene or vinylnaphthalene derivative in the presence of a base and of certain palladium catalysts, such as palladium acetate. The compounds (I) or functional derivatives preparable therefrom are useful, for example, for the preparation of known dyes or fluorescent brighteners, or can be used directly as fluorescent brighteners or as scintillators.
    Type: Grant
    Filed: May 8, 1981
    Date of Patent: June 15, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans-Ulrich Blaser, Dieter Reinehr, Alwyn Spencer
  • Patent number: 4326066
    Abstract: Coumarin compounds of the formula ##STR1## in which the substituents have the meanings given inthe description,are valuable whiteners for natural fibre materials, such as wool, or synthetic polycondensates. They can also be used as scintillators and laser dyestuffs.
    Type: Grant
    Filed: January 7, 1980
    Date of Patent: April 20, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Udo Eckstein, Roderich Raue, Carl-Wolfgang Schellhammer
  • Patent number: 4324628
    Abstract: The present invention relates to a photopolymerization process comprising irradiating a photopolymerizable material with U.V. light of wave length 250 to 400 nm in the presence of a photosensitizing amount of a photoinitiator of formula I, ##STR1## in which R is hydrogen or halogenR.sub.1 is alkyl, cycloalkyl, benzyl, optionally substituted phenyl or (a) ##STR2## either R.sub.2 is optionally substituted alkyl, benzyl, C.sub.6 H.sub.5 --CH.dbd.CH--, 2-thienyl, 2-furyl, 2-(3-chloro)benzothienyl or optionally substituted phenyl, andR.sub.3 is hydrogen or R.sub.2 and R.sub.3 form a radical of formula (b) ##STR3## in which X is a direct bond, --O--, --S--, --CH.sub.2 --, ##STR4## and R.sub.4 and R' have one of the significances of R.sub.2 and R, respectively,with the proviso that when R.sub.1 is (a) R.sub.3 is hydrogen and R.sub.2 and R.sub.4 are free from halogen atoms.
    Type: Grant
    Filed: December 3, 1980
    Date of Patent: April 13, 1982
    Assignee: Sandoz Ltd.
    Inventors: Lajos Avar, Hans-Werner Finck, Evelyne Kalt
  • Patent number: 4321275
    Abstract: The disclosure relates to novel 17,18,19,20-tetranor-prostanoic acid derivatives having prostaglandin-type properties, to a method for their manufacture, and also to pharmaceutical or veterinary compositions containing said novel derivatives and a method of inducing luteolysis in an animal host by use of said novel derivatives.
    Type: Grant
    Filed: May 30, 1974
    Date of Patent: March 23, 1982
    Assignee: Imperial Chemical Industries Limited
    Inventors: Jean Bowler, Neville S. Crossley
  • Patent number: 4316860
    Abstract: Phosphonium compounds of the formula(R).sub.3 P.sup..sym. --CH.sub.2 --X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar.in which R is preferably alkyl having 1 to 4 C atoms, cyclohexyl or phenyl, R.sub.1 is a substituted or unsubstituted aromatic radical, especially a phenyl radical, X is phenylene, 4,4'-biphenylene or 1,4- or 2,6-naphthylene and Y.sup..crclbar. is SO.sub.3.sup..crclbar., SO.sub.2.sup..crclbar. or COO.sup..crclbar., a process for their preparation and a process for the preparation of asymetrically substituted fluorescent brightening agents of the formulaZ--CH.dbd.CH--X--CH.dbd.CH--R.sub.1 Y.sup..crclbar. M.sup..sym.in which R.sub.1, X and Y.sup..crclbar. are as defined above, M.sup.61 is a cation and Z is preferably a substituted or unsubstituted phenyl or 2-phenyl-triazol-4-yl radical, by reacting a bis-phosphonium compound of the formula ##STR1## in which Q.sup..crclbar. is an anion, with an aldehyde of the formula M.sup..sym. Y.sup..crclbar. --R.sub.
    Type: Grant
    Filed: May 15, 1980
    Date of Patent: February 23, 1982
    Assignee: Ciba-Geigy Corporation
    Inventor: Michael Marky
  • Patent number: 4315026
    Abstract: A novel class of chemical compounds useful as pesticides consists of alkylpolyoxysulfinyl and alkylpolythiosulfinyl derivatives of carbamate esters. The preparation of these compounds and their formulation to control insects are exemplified.
    Type: Grant
    Filed: April 11, 1980
    Date of Patent: February 9, 1982
    Assignee: The Regents of the University of California
    Inventors: Mohamed A. H. Fahmy, Tetsuo R. Fukuto, Teruomi Jojima
  • Patent number: 4304728
    Abstract: Compounds are described of the formula ##STR1## in which R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano, 5-tetrazolyl or R.sup.6, where R.sup.5 is hydrogen or C.sub.1-8 alkyl and R.sup.6 is phenyl or naphthyl, the phenyl or naphthyl group being optionally substituted by one or more group selected from halogen, C.sub.1-6 alkyl, C.sub.1-4 alkoxy, hydroxy, benzyloxy, nitro, trifluoromethyl, carboxyl, C.sub.1-4 alkylsulphinyl, C.sub.1-4 alkylsulphonyl, N(R.sup.5).sub.2, NHCOR.sup.5 and SR.sup.5 ; R.sup.2 is R.sup.6 or --CH.dbd.CH--R.sup.6 when R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano or 5-tetrazolyl, or R.sup.2 is --CH.dbd.CH--R.sup.6 when R.sup.1 is R.sup.6 ; R.sup.3 is hydrogen, C.sub.1-6 alkyl, halogen, hydroxy or --OCH.sub.2 R.sup.6 ; and R.sup.4 is hydrogen, C.sub.1-6 alkyl or halogen; and salts thereof. The compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.
    Type: Grant
    Filed: March 27, 1980
    Date of Patent: December 8, 1981
    Assignee: Lilly Industries Limited
    Inventors: Barry P. Clark, William J. Ross, Alec Todd
  • Patent number: 4302460
    Abstract: Compositions which contain a quinolone compound of the general formula ##STR1## wherein n is 0, 1 or 2; R.sub.1 is lower alkyl optionally substituted by hydroxy or C.sub.1-4 alkoxycarbonyl; allyl; propynyl or phenyl- lower alkyl in which the phenyl ring is optionally substituted by 1 or 2 C.sub.1-4 alkoxy groups; R.sub.2 is C.sub.1-4 alkyl with the proviso that when n is 0, R.sub.2 is methyl; and R.sub.3, R.sub.4 and R.sub.5, which may be the same or different, are hydrogen, lower alkyl, lower alkoxy, lower alkanoyl, halo, trifluoromethyl or lower alkylthio show antihypertensive activity.Compounds of general formula ##STR2## in which n, R.sub.1 R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as described above are novel subject to the following provisos (a) when R.sub.3, R.sub.4 and R.sub.4 and R.sub.5 are hydrogen R.sub.2 is methyl and R.sub.1 is lower alkyl, R.sub.1 contains more than one carbon atom, and(b) when R.sub.3 and R.sub.4 are hydrogen, R.sub.5 is hydrogen or 7-methyl, and R.sub.1 is ethyl, R.sub.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: November 24, 1981
    Assignee: The Boots Company Limited
    Inventors: Roy V. Davies, James Fraser, Kenneth J. Nichol, Raymond Parkinson, Malcolm F. Sim, David B. Yates
  • Patent number: 4291176
    Abstract: Insecticidally active vinyl-cyclopropane carboxylic acid esters of the formula ##STR1## are prepared by reacting ##STR2## in which R.sup.12 is a radical selected from the group consisting of ##STR3## with an alcoholate of the formulaM--O--R.sup.8.Various processes for making the intermediates are also described. Many of the intermediates and end products are new.
    Type: Grant
    Filed: August 24, 1977
    Date of Patent: September 22, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Georg Heine, Willy Hartmann
  • Patent number: 4289896
    Abstract: Phosphonic acids are suitable catalysts for the transesterification of alkyl esters of carboxylic acids with aliphatic or cycloaliphatic diols containing more than 3 carbon atoms.
    Type: Grant
    Filed: September 17, 1979
    Date of Patent: September 15, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Lothar Buxbaum
  • Patent number: 4289903
    Abstract: There are provided certain p-phenylalkoxy phenylurea and thiourea compounds useful for the control of undesirable plants in the presence of agronomic crops and to methods for the preparation of said phenylalkoxy phenylurea and thiourea compounds.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: September 15, 1981
    Assignee: American Cyanamid Company
    Inventors: David M. Spatz, Barrington Cross
  • Patent number: 4288607
    Abstract: The invention relates to halogenous polyesters with the recurrent general formula ##STR1## in which at least part of the R's, e.g.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: September 8, 1981
    Assignee: Dynamit Nobel Aktiengesellschaft
    Inventors: Gerhard Bier, Dagmar Kottek, Egon N. Petersen, Hermann Richtzenhain, Norbert Vollkommer
  • Patent number: 4287366
    Abstract: A process for preparing bisphenol sulfone derivatives represented by the general formula (I) ##STR1## where R stands for hydrogen, a halogen, an alkyl radical, a cycloalkyl radical, an aryl radical, an aralkyl radical, hydroxyl group, an alkoxy radical, allyloxy group, carboxyl group, or a carboalkoxy radical, m is an integer of from 1 to 3, and when m is 2 or more, R may be identical to or different from each other, and adjacent Rs may be combined to form a ring, by oxidizing with hydrogen peroxide a compound represented by the general formula (II) ##STR2## where R and m have the same meanings as defined for the formula (I), and n is zero or 1, in the presence of an alkali in an amount more than the equimolar amount thereof relative to said compound in water and/or an organic solvent which do not form any organic peracids under reaction conditions.
    Type: Grant
    Filed: March 10, 1980
    Date of Patent: September 1, 1981
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Akihiro Yamaguchi, Keizaburo Yamaguchi, Hisamichi Murakami, Tadashi Kobayashi
  • Patent number: 4283414
    Abstract: The invention concerns novel pesticidal esters of the pyrethrin or pyrethroid type in which the methylene group bonded to the ester carbonyl and/or ester oxygen bears a fluorine substituent. The compounds of the invention are active against insect pests including flies, moths, aphids and beetles and acarina pests including ticks.
    Type: Grant
    Filed: June 8, 1979
    Date of Patent: August 11, 1981
    Assignee: ICI Australia Limited
    Inventors: Donald W. G. Harney, Peter G. Lehman, Joseph C. Rundle
  • Patent number: 4283551
    Abstract: A group of heat curable resins are provided which have good physical properties, which properties are retained to a surprising degree after prolonged exposure to temperatures as high as 300.degree. C. The products are acetylene end-capped polyesters prepared by reacting a hydroxyphenylacetylene with a diacid chloride of an aromatic dibasic acid such as 4,4'-benzophenone dicarboxylic acid dichloride.
    Type: Grant
    Filed: September 13, 1979
    Date of Patent: August 11, 1981
    Assignee: Gulf Oil Corporation
    Inventors: Wai Y. Chow, Daniel J. Hurley, James H. Rea, S. Paul Thackaberry
  • Patent number: 4275240
    Abstract: 2,2'-Bisphenol sulfoxides are prepared by oxidizing 2,2'-bisphenol sulfides with hydrogen peroxide in the presence of such an organic solvent as not to form any organic peracids under reaction conditions.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: June 23, 1981
    Assignee: Mitsui Toatsu Chemicals, Inc.
    Inventors: Akihiro Yamaguchi, Keizaburo Yamaguchi, Hisamichi Murakami, Tadashi Kobayashi
  • Patent number: 4266074
    Abstract: Substituted acetate compounds represented by the formula ##STR1## which are useful as pesticides and pesticidal composition containing the substituted acetate compounds as active ingredients, as well as processes for preparing the compounds and the compositions are disclosed.
    Type: Grant
    Filed: July 16, 1975
    Date of Patent: May 5, 1981
    Assignee: Sumitomo Chemical Company Limited
    Inventors: Keimei Fujimoto, Nobuo Ohno, Yoshitoshi Okuno, Toshio Mizutani, Isao Ohno, Masachika Hirano, Nobushige Itaya, Takashi Matsuo
  • Patent number: 4233298
    Abstract: This invention is concerned with esters of p-carbonylphenoxy-isobutyric acids of the general formulae: ##STR1## wherein R is a phenyl group substituted by one or two halogen atoms;R' is H, CH.sub.3, C.sub.6 H.sub.5, SCH.sub.3, OCH.sub.3, or, SO.sub.2 CH.sub.3 ;R" is CH.sub.3 or C.sub.2 H.sub.5 ;Y is C.sub.1 -C.sub.4 alkoxy, phenoxy, phenoxy substituted by one or two halogen atoms, or, OCH.sub.2 O--CO--C(CH.sub.3).sub.3 ;Z is C.sub.1 -C.sub.4 alkyl, phenyl or R;NR.sub.1 R.sub.2 is N(CH.sub.3).sub.2 N(C.sub.2 H.sub.5).sub.2, morpholino, piperidino, hexamethylenimino, pyrrolidino.This invention is also concerned with acid addition salts obtained from formula Ia compounds with acids.Compounds of formulae I and Ia are useful as hypocholesterolemiant and hypolipidemiant agents.
    Type: Grant
    Filed: September 1, 1977
    Date of Patent: November 11, 1980
    Assignee: Orchimed SA
    Inventor: Andre Mieville
  • Patent number: 4228029
    Abstract: Liquid crystalline compositions, especially for displays with a twisted nematic phase, comprising at least one compound of the formula ##STR1## wherein X=H, --CHO or --CH.sub.3, R.sup.1 =C.sub.1 --C.sub.10 alkyl, R.sup.2 is a monovalent organic group, for example, --CN; and Y is a single bond or one of the groups --COO-- or ##STR2## The compositions show a high positive dielectric anisotropy (.DELTA..epsilon.), a high .DELTA.n, and a low viscosity, and the mixture system may comprise relatively few components.
    Type: Grant
    Filed: January 24, 1979
    Date of Patent: October 14, 1980
    Assignee: BBC Brown Boveri & Company Limited
    Inventor: Maged A. Osman
  • Patent number: 4218555
    Abstract: Acetylene end-capped polyimide oligomers are prepared by a process including the following sequential steps:1. Preparing an alkanol or ether solution containing substantially 1 molar equivalent of a dialkyl ester of an aromatic tetracarboxylic acid,2. Adding substantially 0.5 to 0.8 molar equivalent of an aromatic diamine to the solution of (1) to form a reaction product between the diacid and the diamine,3. Adding an aminoarylacetylene to the solution of (2) in a quantity sufficient to provide amine groups equivalent to the free carboxylic acid groups present in the product of (2).4. Heating the solution of (3) to vaporize the solvent therefrom, and5. Heating the product of (4) to convert the carboxylic acid groups, the ester groups, and the amino groups thereof to imide groups.The temperature in steps (2) and (3) is maintained below about 50.degree. C. The temperature in steps (4) and (5) is maintained below about 210.degree. C.
    Type: Grant
    Filed: November 1, 1978
    Date of Patent: August 19, 1980
    Assignee: Gulf Oil Corporation
    Inventors: Patricia A. Antonoplos, Clarence D. Bertino, William J. Heilman
  • Patent number: 4206106
    Abstract: The products of the invention are vinyl end-capped oligomers which are prepared from 2,4-bis (p-aminobenzyl) aniline and a vinyl substituted aromatic monoamine, the principal component of which is the compound whose structure is shown in FIG. 3. The products are prepared from either of two (2) precursors. The first precursor is a compound whose structure is shown in FIG. 2 and which is prepared from 2,4-bis (p-aminobenzyl) aniline, a dianhydride of an aromatic tetracarboxylic acid such as 3,3'4,4'-benzophenonetetracarboxylic acid (BTDA) and a vinyl substituted aromatic monoamine, such as 3-aminophenyl-ethylene (APE). The second precursor is a complex amine salt having the structure shown in FIG. 6 and which is prepared from 2,4-bis-(p-aminobenzyl) aniline, a dialkyl ester of BTDA and APE.
    Type: Grant
    Filed: April 5, 1979
    Date of Patent: June 3, 1980
    Assignee: Gulf Oil Corporation
    Inventors: William J. Heilman, Daniel J. Hurley
  • Patent number: 4206107
    Abstract: The products of the invention are acetylene end-capped polyimide oligomers prepared from a dianhydride of an aromatic tetracarboxylic such as 3, 3', 4, 4'-benzophenonetetracarboxylic acid, an aromatic triamine, and a propargyl ester of an amino-substituted aromatic acid such as aminobenzoic acid. The structure of the polyimide oligomers is shown in FIG. 3.
    Type: Grant
    Filed: April 26, 1979
    Date of Patent: June 3, 1980
    Assignee: Gulf Oil Corporation
    Inventors: Wai Y. Chow, S. Paul Thackaberry
  • Patent number: 4206235
    Abstract: The present invention relates to novel 2,5-dihalophenyl-.beta.-substituted sulfone compounds of the formula ##STR1## wherein Q is selected from ##STR2## and wherein: X designates chlorine or bromine,Y designates hydrogen, chlorine, or bromine,Z designates chlorine, bromine, phenyl, halophenyl or --COOR whereinR is a lower alkyl group of up to and including 4 carbon atoms,Z' designates chlorine, bromine or --COOR, wherein R is a lower alkyl of up to and including 4 carbon atoms, provided that whenY is hydrogen, Z' designates --COOR, as herein defined,and to pesticides and especially fungicides containing a compound as defined above as active ingredient. The above compounds are also effective antifungal agents when incorporated in polymeric compositions.
    Type: Grant
    Filed: August 15, 1977
    Date of Patent: June 3, 1980
    Assignee: Yeda Research & Development Co., Ltd.
    Inventors: David Vofsi, Yael Allingham
  • Patent number: 4199597
    Abstract: Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto having antihypertensive activity are preparable by reaction of the appropriate 2,3,6-substituted-4-(polyfluoro-2-hydroxy-2-propyl)phenol or thiophenol with an alkyl ester of a bromoalkanoic acid, followed by hydrolysis to the free acid.
    Type: Grant
    Filed: May 4, 1979
    Date of Patent: April 22, 1980
    Assignee: Schering Corporation
    Inventors: Bernard R. Neustadt, Elijah H. Gold
  • Patent number: 4199595
    Abstract: The invention is m-phenoxybenzyl esters of 2-haloalkyl(oxy-, thio-, sulfinyl-, or sulfonyl)phenylalkanoic acids which are useful insecticidal and acaricidal agents.
    Type: Grant
    Filed: March 20, 1978
    Date of Patent: April 22, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald Berkelhammer, Venkataraman Kameswaran
  • Patent number: 4191776
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine, bromine, methyl, methoxy, methylthio or cyano;R.sub.2 is hydrogen or fluorine;R.sub.3 is carboxyl, (alkoxy of 1 to 6 carbon atoms)-carbonyl, methoxy-(alkoxy of 1 to 6 carbon atoms)-carbonyl, (alkenyloxy of 2 to 6 carbon atoms)-carbonyl, (aralkoxy of 7 to 12 carbon atoms)-carbonyl, phenoxy-carbonyl or pyridyl-methoxy-carbonyl,A is (alkyl of 1 to 3 carbon atoms)-methylene,m is 1 or 2; andn is 0, 1, 2 or 3;and, when R.sub.3 is carboxyl, non-toxic salts thereof formed with an inorganic or organic base. The compounds as well as the salts are useful as antithrombotics, anticholesteremics and anticoagulants.
    Type: Grant
    Filed: November 18, 1977
    Date of Patent: March 4, 1980
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Josef Nickl, Erich Muller, Berthold Narr, Walter Haarmann, Wolfgang Schroter, Rudolf Kadatz
  • Patent number: RE30922
    Abstract: The products of the invention are vinyl end-capped oligomers which are prepared from 2,4-bis (p-aminobenzyl) aniline and a vinyl substituted aromatic monoamine, the principal component of which is the compound whose structure is shown in FIG. 3. The products are prepared from either of two (2) precursors. The first precursor is a compound whose structure is shown in FIG. 2 and which is prepared from 2,4-bis (p-aminobenzyl) aniline, a dianhydride of an aromatic tetracarboxylic acid such as 3,3'4,4'-benzophenonetetracarboxylic acid (BTDA) and a vinyl substituted aromatic monoamine, such as 3-aminophenyl-ethylene (APE). The second precursor is a complex amine salt having the structure shown in FIG. 6 and which is prepared from 2,4-bis-(p-aminobenzyl) aniline, a dialkyl ester of BTDA and APE.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: May 4, 1982
    Assignee: Gulf Oil Corporation
    Inventors: William J. Heilman, Daniel J. Hurley