Abstract: A group of water-soluble polymeric yellow colors and their preparation is disclosed. These colors comprise a plurality of units of a chromophore of the formula ##STR1## wherein M.sup.+ is a pharmaceutically acceptable monovalent cation attached directly to amine units present in a nonchromophoric polymer backbone. In a preferred embodiment of the invention the backbone is a homopolymer or copolymer of vinylamine. These colorants find special utility as nonabsorbable colorants for edibles, especially foods and beverages, where their yellow hue is an excellent color match for existing monomeric azo food colors such as tartrazine, and as components of acid-insoluble pigment lakes which are themselves suitable for use in edibles.

Abstract: Disclosed are additives for hydrocarbon fuels which are the reaction products of a polyamine and an alkyl ester of acrylic or alkyl acrylic acid. A preferred composition is a mixture of the reaction product and oxygenated or non-oxygenated mono- or polyamines.

Abstract: The amino acid 2-amino-4-(2-aminoethoxy)-trans-but-3-enoic acid can be conveniently prepared via novel intermediates from a 2,2'-disubstituted diethyl ether and a dialkyl N-protected amidomalonate starting material using a multi-step process. Preferred starting materials are bis-2-chloroethyl ether and diethyl acetamidomalonate. The process, in a preferred embodiment, proceeds through the key intermediate ethyl-2-acetamido-4-[2-(2-phthalimido)ethoxy]-but-2-enoate.

Abstract: New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

Abstract: This invention relates to a new process for the production of organic polyisocyanates containing polyuret groups, to polyisocyanates obtainable by this process and to the use of the products obtained by the process as an isocyanate component in the production of polyurethane plastics.

Abstract: Polycarboxylic acid-2-hydroxyalkyl esters of the formula ##STR1## wherein A is an aliphatic, cycloaliphatic, or aromatic radical which is optionally substituted or interrupted by heteroatoms, and/or optionally substituted by hydroxyl groups, R.sub.1 is hydrogen or an alkyl radical having 1 to 12 carbon atoms, and R.sub.2 is an alkyl radical having 10 to 22 carbon atoms, n.gtoreq.0 and m.gtoreq.2, with the proviso that m.gtoreq.n and the total of n+m.gtoreq.3, and their use as emulsifying agents and cosmetic emulsions containing them.

Abstract: Compounds of the formula ##STR1## in which R is alkylene, vinylene, methylvinylene, phenylene, cyclohexenylene, 1,2-dichlorovinylene and ethylidene, R.sup.1 and R.sup.2 are alkyl and R.sup.3 is hydrogen or alkyl or their amine salts and their use in retarding the ripening of picked fruits, vegetables and other merchantable materials of plant origin.

Abstract: This invention relates to new pleuromutilins of the formula: ##STR1## wherein either R.sub.1 is ethyl or vinyl,n is an integer from 2 to 5,X is sulphur,a group ##STR2## or a group .dbd.N--R.sub.4.sup.I, whereineither Y and Z are both sulphur, orone of Y and Z is oxygen and the other is sulphur, andR.sub.4.sup.I is hydrogen or a group of the formula: ##STR3## wherein R.sub.1 is as defined above, each of R.sub.2 and R.sub.3 is alkyl of 1 to 10 carbon atoms, orR.sub.2 and R.sub.3 together with the nitrogen atom form a heterocycle of 5 to 7 ring members, and pharmaceutically acceptable acid addition salts and quaternary salts thereof.Processes for the preparation of such compounds are described.The compounds are antibiotics with an antibacterial effect.

Abstract: Hydrocarbylpoly(oxyalkylene) aminoesters which are monoesters of a hydrocarbyl-terminated poly(oxyalkylene) alcohol and a monocarboxylic C.sub.2 -C.sub.20 (amino-substituted) alkanoic acid find use as fuel and lubricating oil additives.

Abstract: Fluorinated poly-(C.sub.2 to C.sub.10) alkylene polyamides (especially alpha, omega-triazaalkanes) in which the endmost nitrogen atoms are acylated by fluorinated carboxylic acid groups and an interior nitrogen atom is acylated by a dibasic acid moiety of the group consisting of (C.sub.4 to C.sub.14) alkane dioic acid moieties and the thiocarbonic acid moieties --C(.dbd.O)S-- and --CS.sub.2 --; wherein per the invention, a radical is terminally attached to the acylating dibasic acid moiety, of the group --CH.sub.2 CH.sub.2 OH, --CH.sub.2 CH(CH.sub.3)OH, --CH.sub.2 CH(OH)CH.sub.2 X (X being halogen or --CN), or ##STR1## The compounds are amphipathic, behaving like surfactants when incorporated with nylon. They are prepared by broadly known methods of producing esters and thioesters of acids. The stain resistance of fibers incorporating these compounds can be improved as to durability and at least partially restored after abrasion of the fiber, by annealing.

Abstract: A sulfonic acid salt of an acyloxyalkylamine is prepared by reaction of an organic acid or amino-acid with a sulfonic acid salt of an alkanolamine. Isocyanates are prepared therefrom by reaction with phosgene.

Abstract: Enamides are prepared by hydrogenating oximes having at least one hydrogen atom at the .alpha.-position in the presence of a carboxylic anhydride using a ruthenium catalyst. These enamides are important to obtain amino group-containing compounds by reduction or polymerization.

Abstract: Novel amine salts of substituted N-phosphonomethylureas are disclosed herein, having the formula ##STR1## in which R, R', and R" are independently C.sub.1 -C.sub.4 alkyl;a is 1 or 2 and b is 2 or 3, such that the sum of a and b is 4; andc is 1 or 2 and d is 0 or 1, such that the sum of c and d is 2.The compounds are useful in regulating the natural growth or development of plants.

Abstract: Novel acetylenic derivatives of .alpha.-amino acids of the following general structure: ##STR1## wherein Z is .beta.-methylthioethyl, .beta.-benzylthioethyl, S-(5'-desoxyadenosin-5' -yl)-S-methylthioethyl, .gamma.-guanidinopropyl, or RHN(CH.sub.2).sub.n --; n is the integer 3 or 4; each R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or ##STR2## wherein R.sub.2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R.sub.1 is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR.sub.4 R.sub.5 wherein each of R.sub.4 and R.sub.5 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms, or ##STR3## wherein R.sub.3 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and the lactams thereof when Z is RHN(CH.sub.

Abstract: This disclosure relates to derivatives of N-trifluoroacetyl-N-phosphonomethylglycinates wherein different moieties are attached to the phosphorus atom, to herbicidal compositions containing same and to the herbicidal use thereof.

Abstract: An optically active lysine alkyl ester.dihydrochloride is racemized by heating at 100.degree. C. to 250.degree. C. under an atmosphere of hydrogen. By combining this process with asymmetric hydrolysis of racemic lysine alkyl ester with enzymes, racemic lysine alkyl ester can be converted all to L-lysine.

Abstract: A compound of the formula: ##STR1## WHEREIN Q is a hydrogen atom, --CH.sub.2 CH(OH)CH.sub.2 Rf or a hydrocarbon residue having a valence corresponding to m which may contain one or more of --O--, --COO--, --NH--, --N.dbd. and ##STR2## IN THE CHAIN, R is a hydrogen atom, a hydrocarbon residue or --CH.sub.2 CH(OH)CH.sub.2 Rf and m is an integer of not less than 1, Rf being a perfluoroalkyl group, an .omega.-hydro-perfluoroalkyl group o an .differential.-chloro-erfluoroalkylgroup having 4 to 20 carbon atoms, which is useful as an agent for rendering fibrous materials oleophobic and anti-soiling and may be prepared by reacting a perfluoroalkylpropylene oxide of the formula: ##STR3## wherein Rf is the same as defined above, with a reagent of the formula:Q'(NHR').sub.mwherein Q' is a hydrogen atom or a hydrocarbon residue having a valence corresponding to m which may contain one or more of --O--, --COO--, --NH-- and --N.dbd.

Abstract: An improved thickening agent is disclosed comprising a polyurea metal salt wherein the polyurea portion of the molecule is prepared by reacting a diisocyanate, a diamine with a monoisocyanate or monoamine. The metal salt is prepared by reacting the polyurea compound with an acid group, such as a carboxylic or a sulfonic acid group, and neutralizing the terminal acid group with a basic metal compound.

Abstract: Lysine ester is produced by heating .alpha.-amino-.epsilon.-capro-lactam with an alcohol. The reaction can be accelerated by adding a small amount of water and an acid or base catalyst.

Abstract: Novel vinyl derivatives of .alpha.-amino acids of the following general structure: ##STR1## wherein R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or ##STR2## wherein R.sub.2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; Z is R.sub.1 OCCH.dbd.CH-- or R.sub.1 OC(CH.sub.2).sub.n -- wherein n is an integer of from 1 to 3; each R.sub.1 is the same and is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR.sub.3 R.sub.4 wherein each of R.sub.3 and R.sub.4 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms and can be the same or different, or ##STR3## wherein R.sub.5 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and the lactams thereof when Z is R.sub.1 OC(CH.sub.2).sub.

Abstract: A series of novel 7-(D-.alpha.-aminophenylacetamido)- and 7-(D-.alpha.-hydroxyphenylacetamido)-.DELTA..sup.3 -cephem derivatives have been prepared wherein a heterocyclic thiomethyl moiety is located at the 3-position of the molecule. These compounds are useful as antibacterial agents for the treatment of diseases caused by Gram-positive and Gram-negative bacteria. Preferred members include 7-(D-.alpha.-hydroxyphenylacetamido)-3-(3-carbamoyl-1,2,4-triazol-5-yl)thi omethylceph-3-em-4-carboxylic acid and 7-(D-.alpha.-hydroxyphenylacetamido)-3-(2-carboxymethoxy-methyl-1,3,4-thia diazol-5-yl)thiomethylceph-3-em-4-carboxylic acid. Alternative methods of preparation are provided for these compounds, including various synthetic routes leading to the required novel heterocyclic thiol intermediates.

Abstract: Novel acetylenic derivatives of .alpha.-amino acids of the following general structure: ##STR1## wherein n is an integer of from 1 to 3; R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or ##STR2## wherein R.sub.2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; each R.sub.1 is the same and is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR.sub.3 R.sub.4 wherein each of R.sub.3 and R.sub.4 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms and can be the same or different, of ##STR3## wherein R.sub.5 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and the lactams thereof when n is 2 or 3; and pharmaceutically acceptable salts and individual optical isomers thereof.

Abstract: The invention relates to completely or partially blocked diisocyanates.

Abstract: N-mono-substituted derivatives of diamino acids are prepared by the reaction of succinimidyl esters of carboxylic acids or substituted carbonic acids with the unprotected diamino acid. The acylation preferentially occurs at the side chain or terminal amino group of the diamino acid. For example, selective acylation of the terminal amino group of lysine occurs without first having protected the 2-amino group. Such acylation has application in the preparation of inter alia N.sup.6 -palmitoyl-lysine.

Abstract: The amidation and esterification of carboxylic acids with amines and hydroxyl group-containing compounds, respectively, are effected without incurring the drawbacks of reaction equilibrium by the reaction of the reactants, one of which has been activated in the reactive group by contact with a phosphonium salt obtained by reacting a phosphorous ester or phosphorous monoester salt with an organic base such as pyridine and an oxidizing agent such as halogens and mono or divalent mercury halide or acetate. The amidation can be applied to the preparation of peptides by the reaction of amino acids and/or peptides in which one of the reactive groups have been protected.

Abstract: Certain N-(2-hydroxyalkyl) derivatives of N-phosphonomethylglycine have been found to be useful as herbicides for the treatment of undesired plants.

Abstract: L-2-amino-4-(2-aminoethoxy)-butanoic acid, methods for its preparation and novel intermediates employed in these processes are disclosed. L-2-amino-4-(2-aminoethoxy)-butanoic acid enhances ethylene production in fruit and therefore has utility as a ripening agent and as an abscission agent.

Abstract: 7.beta.-[(2-Amino-1,2-dioxoethyl)amino]acyl cephalosporins of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl or a salt forming ion; R.sub.1 is hydrogen, lower alkyl, saturated or unsaturated cycloalkyl, phenyl, phenyl-lower alkyl, substituted phenyl or certain heterocyclic groups; R.sub.2 is hydrogen or methoxy; R.sub.3 is hydrogen, lower alkyl or cycloalkyl; and X is hydrogen, lower alkanoyloxy, carbamoyloxy, lower alkoxy, lower alkylthio ##STR2## or certain heterothio groups, are useful as antibacterial agents.

Abstract: New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

Abstract: There is disclosed a fungicide comprising as active ingredient a 1,2-substituted-4-(3',5'-dichlorophenyl) urazole derivative suitable for preventing various diseases of plants including fruit trees, vegetables, rice plants and beans.

Abstract: The subject of the invention are completely or partially blocked diisocyanates of the following formula (III) ##STR1## wherein R.sub.1 denotes the radical ##STR2## or NCO and R denotes the methyl, ethyl, propyl, iso-propyl, n-butyl, tert.-butyl, iso-butyl, sec.-butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl and dodecyl radical.

Abstract: Compounds having the structure ##STR1## wherein D is hydrogen or methoxy were synthesized and found to be antibacterial agents.

Abstract: Certain N-(2-hydroxyalkyl) derivatives of N-phosphonomethylglycine have been found to be useful as herbicides for the treatment of undesired plants.