Plural Rings In Alcohol Moiety Patents (Class 560/194)
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Publication number: 20130199724Abstract: The invention provides epoxy and oxetane compositions including the novel acyloxy and N-acyl curing agents described herein. Use of invention curing agents result in cured adhesive compositions with remarkably increased adhesion and reduced hydrophilicity when compared to resins cured with other types of curing agents. Furthermore, the curatives of this invention do not interfere with free-radical cure and are thus suited for use in hybrid cure thermoset compositions.Type: ApplicationFiled: March 15, 2013Publication date: August 8, 2013Applicant: Designer Molecules, Inc.Inventor: Designer Molecules, Inc.
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Patent number: 8492579Abstract: The present invention relates to an improved method for producing all-E astaxanthin dimethyldisuccinate of the formula I.Type: GrantFiled: February 4, 2011Date of Patent: July 23, 2013Assignee: BASF SEInventors: Hansgeorg Ernst, Walter Dobler, Andreas Keller, Klaus Henrich
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Publication number: 20130184263Abstract: The present invention relates to compounds characterized by having a structure according to the following Formula I: or a pharmaceutically acceptable salt thereof. Compounds of the present invention are useful for the treatment or prevention of HIV.Type: ApplicationFiled: December 14, 2012Publication date: July 18, 2013Applicant: GlaxoSmithKline LLCInventor: GlaxoSmithKline LLC
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Patent number: 8487139Abstract: The invention relates to novel curcumin and tetrahydrocurcumin derivatives, which have been modified at one phenolic group to incorporate more-reactive groups. The curcumin and tetrahydrocurcumin derivatives are in the form of monomers, dimmers, and polymers.Type: GrantFiled: October 12, 2007Date of Patent: July 16, 2013Assignee: The Research Foundation of the City University of New YorkInventors: Krishnaswami Raja, Probal Banerjee, Andrew Auerbach, Wei Shi, William L'Amoreaux
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Publication number: 20130177952Abstract: The present invention relates to methods of producing ingenol-3-angelate (I) from ingenol (II). Furthermore, the invention relates to intermediates useful for the synthesis of ingenol-3-angelate (I) from ingenol (II) and to methods of producing said intermediates.Type: ApplicationFiled: July 8, 2011Publication date: July 11, 2013Inventors: Thomas Högberg, Gunnar Grue-Sørensen, Xifu Liang, Anne Marie Horneman, Anders Klarskov Petersen
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Publication number: 20130134354Abstract: The invention provides a compound having two polymerizable groups, wherein one is bonded directly to the ring and the other is bonded to the ring through a spacer, as a compound in which the polymerizability is not decreased and the solubility is high in a liquid crystal composition. A compound represented by formula (1), wherein in formula (1), for example, A1 and A2 are 1,4-phenylene in which at least one hydrogen has been replaced by fluorine; Z1 is alkylene having 1 to 12 carbons; Z2 is alkylene having 1 to 12 carbons; X1 is hydrogen, fluorine, methyl or trifluoromethyl; P1 is a polymerizable group; and a is an integer from 0 to 3.Type: ApplicationFiled: August 27, 2012Publication date: May 30, 2013Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: YASUYUKI GOTOH, MAIKO MATSUKUMA
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Publication number: 20130131169Abstract: Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH2 or CH?CH, n represents an integer of 0 to 4 when A is CH2, or 1 when A is CH?CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.Type: ApplicationFiled: January 11, 2013Publication date: May 23, 2013Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventor: Takasago International Corporation
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Publication number: 20130093975Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (“polymer sustained”) or PSA (“polymer sustained alignment”) type.Type: ApplicationFiled: June 1, 2011Publication date: April 18, 2013Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Andreas Taugerbeck, Achim Goetz, Stephan Derow
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Publication number: 20130085180Abstract: The present invention relates to prodrug derivatives of pentamidine, their use in the treatment and/or prophylaxis of diseases such as tumor diseases, as well as leishmaniasis, trypanosomiasis, pneumocystis carinii pneumonia (PcP), and malaria.Type: ApplicationFiled: October 5, 2012Publication date: April 4, 2013Applicant: Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KGInventors: Bernd CLEMENT, Joscha KOTTHAUS, Juerke KOTTHAUS, Dennis SCHADE
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Patent number: 8372307Abstract: The invention relates to new cyclohexylene reactive mesogens (RM), polymers derived thereof, liquid crystal (LC) media comprising them, and the use of the compounds, polymers and liquid crystalline media in optical, electrooptical, electronic, semiconducting or luminescent components or devices, in decorative, security, cosmetic or diagnostic applications, especially in the polymer stabilised blue phase.Type: GrantFiled: October 26, 2007Date of Patent: February 12, 2013Assignee: Merck Patent GmbHInventors: Louise Diane Farrand, Kevin Adlem, Andreas Taugerbeck, John Patrick, Christopher John Dunn, Janice McCreary
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Publication number: 20130030212Abstract: Provided are an alicyclic structure-containing compound, a (meth)acrylate, and a method for producing the ester. The compound and the ester are useful as a monomer and the like for a photoresist used in semiconductor manufacturing and excellent in solubility, compatibility, defect reduction, roughness improvement, and the like, realized by using an alicyclic structure-containing compound containing a linking group having an ester bond and/or a linking group having an ether bond, a (meth)acrylate derived from the alicyclic structure-containing compound, and a method for producing the ester.Type: ApplicationFiled: September 28, 2012Publication date: January 31, 2013Applicant: IDEMITSU KOSAN CO., LTD.Inventor: IDEMITSU KOSAN CO., LTD.
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Publication number: 20130026132Abstract: A planarizing film-forming composition for a hard disk that is a non-magnetic filler is sufficiently filled into fine grooves on a magnetic material surface (surface), and is required not to cause contraction in the filled parts at the time of photo-curing (at the time of exposure) and post-exposure baking; and a method for producing a hard disk using the composition. The composition comprising at least one polyfunctional (meth)acrylate compound being in a liquid state at room temperature and atmospheric pressure and having a molecular weight of 300 to 10,000. The compound preferably has 2 to 20 (meth)acrylate groups in the molecule, or the compound preferably has a molecular weight of 300 to 2,300. A method for producing a hard disk comprising: forming a concave-convex shape on the surface; covering the surface having the concave-convex shape with the composition; and etching the covered surface for planarization until the surface is exposed.Type: ApplicationFiled: April 18, 2011Publication date: January 31, 2013Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Taku Kato, Junpei Kobayashi, Keisuke Shuto, Masayoshi Suzuki
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Publication number: 20130029922Abstract: The invention provides novel compounds and formulations of turmeric oil, fish oil, aspirin and anti-cancer drugs (paclitaxel) having anti-inflammatory, analgesic and/or anti-cancer activity.Type: ApplicationFiled: June 29, 2012Publication date: January 31, 2013Applicant: ORGANOMED CORPORATIONInventor: James N. Jacob
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Publication number: 20130021568Abstract: The present invention discloses a reactive monomer of liquid crystal. The reactive monomer of liquid crystal is added with at least one fluoro group. Because hydrocarbon bonds of a side chain of polyimide surface of an alignment film has a fluorophobic effect, the fluoro group of the reactive monomer of liquid crystal can lower the interaction between the polyimide surface of the alignment film and the reactive monomer of liquid crystal to thus evenly deposit the liquid crystal composition containing the reactive monomers of liquid crystal onto the polyimide surface of the alignment film. Thus, it can avoid from occurring the phenomenon of drop Mura defect occurred during implementing the ODF technology.Type: ApplicationFiled: August 11, 2011Publication date: January 24, 2013Applicant: Shenzhen China Star Optoelectronics Technology Co., Ltd.Inventors: Chung-Ching Hsieh, Chengming He
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Publication number: 20120327357Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilised blue phase, and in LC media for LC displays of the PS or PSA type (“polymer sustained” or “polymer sustained alignment”), and to LC media and LC displays comprising these compounds.Type: ApplicationFiled: February 24, 2011Publication date: December 27, 2012Applicant: Merck Patent Gesellschaft Mit Beschrankter HaftungInventors: Axel Jansen, Thorsten Kodek, Helmut Haensel, Erdal Durmaz
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Publication number: 20120298916Abstract: The invention relates to 1,1-disubstituted cyclohexane derivatives containing one or more polymerisable groups, and to liquid-crystalline media comprising at least one compound of the formula I. At least one of the polymerisable groups is located at the geminally substituted position of the cyclohexane ring. The compounds are suitable for the stabilisation of liquid-crystalline phases. Examples of polymer-stabilised blue phases are indicated.Type: ApplicationFiled: December 23, 2010Publication date: November 29, 2012Applicant: Merck Patent Gesellschaft Mit Beschrankter HaftungInventors: Axel Jansen, Thorsten Kodek, Helmut Haensel, Erdal Durmaz
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Patent number: 8313669Abstract: The present invention relates to a liquid-crystal (LC) display of the PS (polymer stabilized) or PSA (polymer sustained alignment) type, and to polymerizable compounds and LC media for use in PS (polymer stabilized) and PSA displays.Type: GrantFiled: July 31, 2008Date of Patent: November 20, 2012Assignee: Merck Patent Gesellschaft mit Beschränkter HaftungInventors: Georg Bernatz, Andreas Taugerbeck
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Publication number: 20120289614Abstract: This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products.Type: ApplicationFiled: July 29, 2012Publication date: November 15, 2012Applicant: BEZWADA BIOMEDICAL, LLCInventor: Rao S. Bezwada
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Publication number: 20120270836Abstract: The present invention relates to compositions and methods for the treatment of Alzheimer's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Alzheimer's disease and related disorders. In particular, the invention concerns compounds which, alone or in combination(s), can effectively modulate synapse function and/or angiogenesis and/or cell stress response. The invention also relates to methods of producing a drug or a drug combination for treating Alzheimer's disease and to methods of treating Alzheimer's disease or a related disorder.Type: ApplicationFiled: May 2, 2012Publication date: October 25, 2012Applicant: PHARNEXTInventors: Daniel Cohen, Ilya Chumakov, Serguei Nabirochkin
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Publication number: 20120236246Abstract: Provided is a liquid crystal composition satisfying at least one of characteristics such as high maximum temperature of a nematic phase, low minimum temperature of the nematic phase, small viscosity, suitable optical anisotropy, large negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light and high stability to heat, or having a suitable balance regarding at least two of the characteristics. Also provided is an AM device having a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth. The liquid crystal composition contains a specific compound having a polymerizable group as a first component, a specific compound having a large negative dielectric anisotropy and a low minimum temperature as a second component, or a specific compound having a small viscosity or a large maximum temperature as a third component, and a liquid crystal display device contains the composition.Type: ApplicationFiled: December 22, 2010Publication date: September 20, 2012Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: Yoshimasa Furusato, Eriko Kurihara, Maiko Ito
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Publication number: 20120232228Abstract: Compounds are provided according to structure 1: in which R?H or methyl and R2=optionally substituted C1-C20 alkyl, optionally substituted C6-C20 aryl, part of a oligomeric or polymeric residue (>C20), which can be optionally substituted.Type: ApplicationFiled: March 13, 2012Publication date: September 13, 2012Applicant: DSM IP ASSETS B.V.Inventors: Joanna KLEIN NAGELVOORT, Cornelis DEN BESTEN, Johan Franz Gradus JANSEN
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Patent number: 8252389Abstract: The invention relates to novel mesogenic dimeric compounds which are especially suitable for use in birefringent films with negative optical dispersion, to novel liquid crystal (LC) formulations and polymer films comprising them, and to the use of the dimers, formulations and films in optical, electrooptical, electronic, semiconducting or luminescent components or devices.Type: GrantFiled: August 29, 2008Date of Patent: August 28, 2012Assignee: Merck Patent Gesellschaft mit Beschränkter HaftungInventors: Kevin Adlem, Owain Llyr Parri, Karl Skjonnemand, David Wilkes
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Publication number: 20120182516Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (“polymer sustained”) or PSA (“polymer sustained alignment”) type.Type: ApplicationFiled: August 30, 2010Publication date: July 19, 2012Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Andreas Taugerbeck, Achim Goetz
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Publication number: 20120178844Abstract: The invention pertains to high-molecular photoinitiator compounds comprising a photoactive moiety Q and an amine functionality, preferably a tertiary amino group, where the photoactive moiety Q is a benzoyl photoactive moiety.Type: ApplicationFiled: July 26, 2010Publication date: July 12, 2012Applicant: BASF SEInventors: Markus Frey, Christophe Frossard, Katia Studer, Bruno Spony, Patrizia Sgambati
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Publication number: 20120156255Abstract: A polymeric matrix for delivery of an HMG CoA reductase inhibitor such as a statin to tissue such as cardiac tissue in need thereof for the treatment or prevention of a disease or defect such as atrial fibrillation has been developed. In the preferred embodiment, a statin is delivered by means of a patch sutured to cardiac tissue at the time of cardiothoracic surgery. In the most preferred embodiment, the patch is a biodegradable material providing controlled or sustained release over a prolonged period of time, such as a week. Suitable materials include extracellular matrix, or other biodegradable hydrogels or polymeric materials providing sustained or controlled release of statin at the site of application.Type: ApplicationFiled: December 16, 2011Publication date: June 21, 2012Inventors: Jaipal Singh, Nicolas Chronos
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Publication number: 20120153271Abstract: A leaving substituent-containing compound including a partial structure represented by the following General Formula (I): where a pair of X1 and X2 or a pair of Y1 and Y2 each represent a hydrogen atom; the other pair each represent a group selected from the group consisting of a halogen atom and a substituted or unsubstituted acyloxy group having one or more carbon atoms; a pair of the acyloxy groups represented by the pair of X1 and X2 or the pair of Y1 and Y2 may be identical or different, or may be bonded together to form a ring; R1 to R4 each represent a hydrogen atom or a substituent; and Q1 and Q2 each represent a hydrogen atom, a halogen atom or a monovalent organic group, and may be bonded together to form a ring.Type: ApplicationFiled: September 9, 2010Publication date: June 21, 2012Inventors: Daisuke Goto, Satoshi Yamamoto, Toshiya Sagisaka, Takuji Kato, Takashi Okada, Masato Shinoda, Shinji Matsumoto, Masataka Mohri, Keiichiro Yutani
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Publication number: 20120156619Abstract: The present invention relates to an acrylate-based compound that includes an organic acid having two or more acrylate groups and one or more phenolic acid structures in one molecule, and a photosensitive composition including the same. It is possible to shorten a developing time in a photolithography process without damaging photosensitivity by using the photosensitive composition according to the present invention.Type: ApplicationFiled: November 18, 2011Publication date: June 21, 2012Applicant: LG CHEM, LTD.Inventors: Keon Woo LEE, Sang Kyu KWAK, Changsoon LEE, Hyehyeon KIM
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Patent number: 8183405Abstract: Disclosed herein are novel obovatol derivatives represented by Chemical Formula 1, and pharmaceutically acceptable salts thereof. Having the ability to inhibit the growth of cancer cells and induce apoptosis in cancer cells, the derivatives or pharmaceutically acceptable salts thereof are useful in the prevention and treatment of cancer and in the suppression of cancer metastasis. Also, a method for preparing the derivatives, and pharmaceutical compositions comprising the derivatives as active ingredients are disclosed. wherein R1, R2 and R3 are as defined in the specification.Type: GrantFiled: July 28, 2008Date of Patent: May 22, 2012Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Byoung-Mog Kwon, Dong Cho Han, Su-Kyung Lee, Hye-Nan Kim, Young-Min Han, Dae-Seop Shin
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Publication number: 20120123074Abstract: The present invention provides an optical anisotropic material having a good light stability, and provides a di(meth)acrylate compound represented by the following formula (1) and a polymerizable liquid crystalline composition that are suitable for the production of the optical anisotropic material. Further, the present invention provides an optical element having a good light stability and an optical information writing/reading device using the same.Type: ApplicationFiled: January 5, 2012Publication date: May 17, 2012Applicant: Asahi Glass Company, LimitedInventors: Satoshi OKADA, Makoto Hasegawa, Hiroshi Kumai, Hiromichi Nagayama
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Publication number: 20120092608Abstract: Provided is a polymerizable compound with large solubility in a liquid crystal composition and high reactivity irradiated by ultraviolet in the longer wavelength range. Provided is a liquid crystal composition that satisfies at least one of characteristics such as high maximum temperature of a nematic phase, low minimum temperature of a nematic phase, small viscosity, suitable optical anisotropy, large negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light and high stability to heat, or that is suitably balanced between at least two of the characteristics.Type: ApplicationFiled: May 7, 2010Publication date: April 19, 2012Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: Maiko Ito, Keiji Kimura, Norikatsu Hattori, Eriko Saegusa
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Publication number: 20120069289Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, and to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays, especially in LC displays of the PS (polymer stabilised) and PSA (polymer sustained alignment) type.Type: ApplicationFiled: April 19, 2010Publication date: March 22, 2012Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Andreas Taugerbeck, Alexander Hahn, Achim Goetz
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Publication number: 20120070492Abstract: The invention relates to pharmaceutical compositions comprising rhein or diacerein or salts or esters or prodrugs thereof, optionally with one or more pharmaceutically acceptable excipients. The invention also relates to the methods for preparing such compositions.Type: ApplicationFiled: September 13, 2008Publication date: March 22, 2012Inventors: Rahul Dabre, Girish Kumar Jain, Cyril Estanove, François Pruvost, Roshanlal Sandal, Prashant Mandaogade, Premchand Nakhat
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Publication number: 20120046291Abstract: The present invention concerns novel pharmaceutically active triterpene derivatives, pharmaceutical compositions containing the same, their use as medicaments, and the use of the compounds for the manufacture of specific medicaments. The present invention also concerns a method of treatment involving administration of the compounds. Specifically, the compounds are derivatives of betulinic acid having substitutions at one or more of the C-3, C2-8 and C-19 positions as further described herein. The novel compounds are useful as antiretroviral agents. In particular, the novel compounds are useful for the treatment of Human Immunodeficiency Virus (HIV).Type: ApplicationFiled: November 2, 2007Publication date: February 23, 2012Inventors: Theodore J. Nitz, Christian Montalbetti, Richard Mears, Xinjie Gai, Edward Glenn
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Publication number: 20120035196Abstract: [Problem] The present invention has an object to provide a compound having a GPR40 agonistic activity, which is useful as a pharmaceutical composition, an insulin secretion promoter, or an agent for preventing/treating diabetes. [Means for Solution] The present inventors have extensively studied a compound having a GPR40 agonistic activity, and as a result, they have found that the compound (I) of the present invention or a pharmaceutically acceptable salt thereof, in which a carboxylic acid is bonded to a bicyclic or tricyclic moiety through methylene, and further, a benzene ring substituted with a monocyclic 6-membered aromatic ring is bonded to a bicyclic or tricyclic moiety through —O-methylene or —NH-methylene, has an excellent GPR40 agonistic activity. They have also found that the compound has an excellent insulin secretion promoting action and strongly inhibits increase in the blood glucose after glucose loading, thereby completing the present invention.Type: ApplicationFiled: April 21, 2010Publication date: February 9, 2012Inventors: Kenji Negoro, Kei Ohnuki, Yasuhiro Yonetoku, Kazuyuki Kuramoto, Yasuharu Urano, Hideyuki Watanabe
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Publication number: 20120026442Abstract: The present invention provides a liquid crystal display device producing less image sticking. The liquid crystal display device of the present invention comprises: a pair of substrates; and a liquid crystal layer between the substrates, wherein at least one of the substrates comprises an alignment film and a photopolymer film on the alignment film, the photopolymer film comprises polymers constituted by a photopolymerizable monomer, the photopolymerizable monomer includes two or more polymerizable functional groups, the polymerizable functional groups are bonded to each other through two or more aromatic rings, the aromatic rings include at least one naphthalene ring, and a bond between the naphthalene ring and another aromatic ring has a rotational degree of freedom.Type: ApplicationFiled: November 18, 2009Publication date: February 2, 2012Inventors: Yohei Nakanishi, Yuichiro Yamada, Masanobu Mizusaki
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Publication number: 20120003198Abstract: The invention relates to the improvement of visual performance, particularly of visual performance in the darkness, by administration of a colorant that is capable of being incorporated into eye tissue and/or causing yellowing of eye tissue, especially carotenoids, such as lutein and zeaxanthin.Type: ApplicationFiled: September 8, 2011Publication date: January 5, 2012Applicant: DSM IP ASSETS B.V.Inventors: Felix Barker, Regina Goralczyk, Wolfgang Schalch
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Publication number: 20110294830Abstract: The present invention provides a nitrogen-containing compound represented by formula (I1) (in formula (I1), R0 represents a nitro group or the like, Z represents an optionally substituted aryl group or the like, R3 represents a hydrogen atom or the like, Y represents a nitro group or the like, n represents an integer of 0 to 3, D represents an optionally substituted 5-membered to 8-membered hydrocarbon ring group or heterocyclic group having or not having a substituent other than substituent X, X represents a group represented by formula (II-1) (in formula (II-1), R1 and R2 respectively and independently represent a hydrogen atom or the like), A represents a carbon atom or the like, n1 represents an integer of 0 to 2) or a salt thereof, and an insecticide, miticide, sanitary insect pest control agent, or harmful organism control agent including as an active ingredient thereof the nitrogen-containing compound or the salt thereof.Type: ApplicationFiled: February 5, 2010Publication date: December 1, 2011Applicant: Nippon Soda Co., Ltd.Inventors: Jyun Iwata, Masahiro Kawaguchi, Akiko Mizui
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Publication number: 20110294948Abstract: Disclosed is a (meth)acrylate compound which can provide a cured article having a high refractive index and excellent transparency and heat resistance, and which has superior handling characteristics; further disclosed are a curable composition containing the (meth)acrylate compound, and a cured article thereof. The (meth)acrylate compound contains an aromatic group represented by the following general formula (1), the curable composition comprising the aromatic-group containing (meth)acrylate compound, and the cured article thereof. (In the formula, R1, R2, R3 and R4 are each independently a hydrogen atom or a methyl group; X is an organic group having an aromatic group and 6 to 30 carbon atoms; and a and b are each independently an integer of 0 to 3.Type: ApplicationFiled: February 9, 2010Publication date: December 1, 2011Applicant: SHOWA DENKO K.K.Inventors: Yoshifumi Urakawa, Shigeru Yamaki, Nobuaki Ishii, Yoshihiko Maeda
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Publication number: 20110288330Abstract: An optical material organic compound having characteristics that the dispersion characteristic (Abbe number (?d)) and the secondary dispersion characteristic (?g,F) of the refractive index are high, the transmittance in the visible light region is high, and the chromatic aberration correction function delivers high performance, which represented by the general formula (1) or (2) is provided.Type: ApplicationFiled: May 20, 2011Publication date: November 24, 2011Applicant: CANON KABUSHIKI KAISHAInventor: Terunobu Saitoh
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Publication number: 20110288083Abstract: The present invention relates to a method of identifying compounds useful in inhibiting protein kinase-like endoplasmic reticulum protein kinase (PERK). The method comprises providing a first model comprising PERK active domains, where the said active domains are selected from the group consisting of the peptide spanning from amino acid residue Asp144 to amino acid residue Ser191 of SEQ ID NO: 1 and a peptide comprising the amino acid residue at position 7 of SEQ ID NO: 1, providing one or more candidate compounds, evaluating contact between the candidate compounds and the first model to determine which of the one or more candidate compounds have an ability to bind to and/or fit in the first model, and identifying the compounds which, based on said evaluating, have the ability to bind to and/or fit in the first model as compounds potentially useful for inhibiting PERK.Type: ApplicationFiled: May 19, 2011Publication date: November 24, 2011Applicant: NEW YORK UNIVERSITYInventors: Timothy CARDOZO, Hong WANG, David Ron
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Publication number: 20110261311Abstract: The present invention relates to polymerisable compounds, to processes and intermediates for the preparation thereof, to the use thereof for optical, electro-optical and electronic purposes, in particular in liquid-crystal (LC) media and LC displays having a polymer-stabilised blue phase, and in LC media for LC displays of the PS or PSA (“polymer sustained” or “polymer sustained alignment”) type, and to LC media and LC displays comprising these compounds.Type: ApplicationFiled: April 26, 2011Publication date: October 27, 2011Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Axel Jansen, Andreas Taugerbeck, Helmut Haensel, Achim Goetz
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Publication number: 20110263693Abstract: Based on the discovery that celastrol and gedunin are Hsp90 inhibitors, the present invention provides novel inhibitors of Hsp90. and pharmaceutically acceptable salts, derivatives, and compositions thereof. The invention provides two classes of compounds. One class includes celastrol and its derivatives. The other class includes gedunin and its derivatives. The present invention further provides methods for treating disorders wherein Hs?90 inhibition is desired (e.g., proliferative diseases, cancer, inflammatory diseases, fungal infections, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. Celastrol, gedunin, and derivatives thereof are particularly useful in the treatment of prostate cancer, breast cancer, ovarian cancer, lung cancer, and leukemia.Type: ApplicationFiled: March 30, 2007Publication date: October 27, 2011Applicants: DANA-FARBER CANCER INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Haley Vinson-Hieronymus, Todd R. Golub, Justin Lamb, Kimberly Stegmaier
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Patent number: 8043789Abstract: A photosensitive compound whose size is smaller than conventional polymer for photoresist, and which has well-defined (uniform) structure, and a photoresist composition including the same are disclosed. The photosensitive compound represented by the following formula. Also, the present invention provides a photoresist composition comprising 1 to 85 wt % (weight %) of the photosensitive compound; 0.05 to 15 weight parts of a photo-acid generator with respect to 100 weight parts of the photosensitive compound; and 10 to 5000 weight parts of an organic solvent. In the formula, n is 0 or 1, x is 1, 2, 3, 4 or 5, y is 2, 3, 4, 5 or 6, z is 0, 1, 2, 3 or 4, R, R? and R? are independently hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms, and R?? is a hydrogen atom or hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms.Type: GrantFiled: December 17, 2008Date of Patent: October 25, 2011Assignee: Dongjin Semichem Co., Ltd.Inventors: Jae-Woo Lee, Min-Ja Yoo, Jun-Gyeong Lee, Young-Bae Lim, Jae-Hyun Kim
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Patent number: 8039663Abstract: The invention is based on the discovery that certain well-defined compounds derived from pentacyclopentadecane dimethanol are useful components in adhesive formulations. In particular, the invention compounds described herein provide high Tg values and low shrinkage. Compounds of the invention are useful as adhesives for use in the semiconductor packaging industry.Type: GrantFiled: April 9, 2008Date of Patent: October 18, 2011Assignee: Designer Molecules, Inc.Inventor: Stephen M. Dershem
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Publication number: 20110251421Abstract: The present disclosure provides analogs and derivatives of phorbol compounds for the treatment of viral infections, neoplastic diseases, inflammatory reactions, and use as analgesics.Type: ApplicationFiled: June 21, 2011Publication date: October 13, 2011Applicant: SALVIA SCIENCES, INC.Inventors: Rensheng Xu, Weimin Zhao, Chun Jiang
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Publication number: 20110224324Abstract: A polymerizable photoinitiator is represented by Formula (I): wherein R1, R2 and R3 are independently selected from the group consisting of a hydrogen, an optionally substituted alkyl group and an optionally substituted aryl group or R1 and R3 represent the necessary atoms to form a five to eight membered ring; p, w, y and z are all integers with y representing a value 1 to 6; p representing the sum of w and z; p representing a value of 1 to 6; w=1 to (p?z) and z=0 to (p?w); L represents an optionally substituted (p+y)-valent linking group comprising 1 to 14 carbon atoms; A represents a radically polymerizable group selected from the group consisting of an acrylate group, a methacrylate group, a styrene group, an acryl amide group, a methacryl amide group, a maleate group, a fumarate group, an itaconate group, a vinyl ether group, an allyl ether group, an allyl ester group and a vinyl ester group; and X represents a photoinitiating moiety including at least one group capable of initiating a free radical pType: ApplicationFiled: December 1, 2009Publication date: September 15, 2011Applicant: AGFA GRAPHICS NVInventors: Johan Loccufier, Luc Van Maele, Jaymes Van Luppen, Roland Claes
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Patent number: 8017800Abstract: The present invention provides an adamantyl group containing epoxy-modified (meth)acrylate and a resin composition containing it which are imparted by transparency, optical characteristics such as (durable) light resistance and the like, heat-resistance, and good mechanical properties. For example, they are an adamantyl group containing epoxy-modified (meth)acrylate having the following general formula (I) and a composition containing it. In the formula, R1 represents a hydrogen atom or a methyl group, and R2 represents a halogen atom or an aliphatic hydrocarbon group which may contain a hetero atom. Plural R2 may be the same or different, and m represents an integer of 0 to 4 and n represents an integer of 0 or more.Type: GrantFiled: July 7, 2010Date of Patent: September 13, 2011Assignee: Idemitsu Kosan Co., Ltd.Inventors: Yasunari Okada, Hajime Ito, Hideki Yamane, Nobuaki Matsumoto
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Publication number: 20110196170Abstract: The present invention relates to an improved method for producing all-E astaxanthin dimethyldisuccinate of the formula I.Type: ApplicationFiled: February 4, 2011Publication date: August 11, 2011Applicant: BASF SEInventors: HANSGEORG ERNST, Walter Dobler, Andreas Keller, Klaus Henrich
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Publication number: 20110190388Abstract: Several ursolic acid derivatives and pharmaceutical compositions thereof are provided. The ursolic acid derivatives and the pharmaceutical compositions thereof have at least one of an anticancer and an anti-inflammatory effects. A method for increasing a reactive oxygen species in a cell is also provided. The method comprises a step of providing the cell with a pharmaceutical composition including an ursolic acid derivative.Type: ApplicationFiled: May 18, 2010Publication date: August 4, 2011Applicant: KAOHSIUNG MEDICAL UNIVERSITYInventors: Chun-Nan Lin, Huang-Yao Tu, A-Mei Huang, Bai-Luh Wei, Kim-Hong Gan, Tzyh-Chyuan Hour, Shyh-Chyun Yang, Yeong-Shiau Pu, Shen-Jeu Won
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Patent number: 7959989Abstract: The present invention relates to a novel cyclic olefin compound, a polymer including the cyclic olefin compound, a liquid crystal alignment film including the polymer, and a liquid crystal display device including the liquid crystal alignment film. Since the polymer includes the cyclic olefin compound as a main chain, the thermal stability is excellent and the photoreactive speed is high. Accordingly, the production time can be reduced, the production cost can be reduced, and the anchoring force of the liquid crystal can be increased because the alignment property is stabilized due to the curing.Type: GrantFiled: March 6, 2008Date of Patent: June 14, 2011Assignee: LG Chem, Ltd.Inventors: Heon Kim, Sung-Ho Chun, Hee-Jin Lee, Dmitry Kravchuk, Kyung-Jun Kim, Sang-Kook Kim, Sung-Joon Oh, Hye-Ran Seong, Byung-Hyun Lee, Hye-Won Jeong, Jung-Ho Jo, Yun-Jeong Lee, Dong-Hyun Oh