Polycarbamic Patents (Class 560/25)
  • Patent number: 10519336
    Abstract: This disclosure relates to a coating composition including a polyisocyanate chain extended NH functional pre-polymer, a method for coating of a metallic or plastic substrate as well as the use of the polyisocyanate chain extended NH functional pre-polymer for improving the adhesion of a coating composition on a metallic or plastic substrate and/or for improving the adhesion between two adjacent layers of multiple layers and the use of the coating composition in a one-component coating composition or two-component coating composition.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: December 31, 2019
    Assignee: Axalta Coating Systems IP Co., LLC
    Inventors: Jozef Theresia Huybrechts, Charlotte Enkisch-Krug, Leen Tanghe, Carmen Flosbach, Ann Vaes
  • Patent number: 10501406
    Abstract: The invention relates to polyphenyl polymethylene polyisocyanates having an NCO number of at least 29% comprising less than 2% by weight ureas, less than 8% by weight carbodiimides or uretonimines and less than 1000 ppm organic chlorine compounds. The polyphenyl polymethylene polyisocyanates can be prepared according to the invention by reacting (i) polyphenyl polymethylene polyamines with organic carbonates to give the corresponding polyphenyl polymethylene polycarbamates, (ii) by thermally cleaving the polyphenyl polymethylene polycarbamates to give the polyphenyl polymethylene polyisocyanates, wherein, prior to the thermal cleavage, the free amino groups or urea groups present in the carhamate crude mixture comprising the polyphenyl polymethylene polycarbamates are reacted with a derivatizing reagent to give amide groups or urethane groups.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: December 10, 2019
    Assignee: BASF SE
    Inventors: Michael Lorenz, Axel Franzke, Robert Baumann, Michael Bock, Geert Janssens
  • Patent number: 10385231
    Abstract: This invention relates to a coating composition, a method for coating of a metallic substrate as well as the use of the coating in a two-component coating composition.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: August 20, 2019
    Assignee: AXALTA COATING SYSTEMS IP CO., LLC
    Inventors: Charlotte Enkisch-Krug, Carmen Flosbach, Ann Vaes, Leen Tanghe, Jozef Huybrechts
  • Patent number: 10358523
    Abstract: 1) Polyurethane composition comprising: a) at least 98% by weight of at least one non-hot-melt polyurethane bearing NCO end groups based on diphenyl methane diisocyanates (MDI), b) a MDI monomer content of less than or equal to 1% by weight, c) at least one particular isocyanate compound with a molar volume of less than or equal to 300 milliliters per mole. 2) Process for preparing a polyurethane composition as defined previously, and an adhesive, mastic and/or surface coating composition formulated from such a polyurethane composition.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: July 23, 2019
    Assignee: BOSTIK SA
    Inventor: Federico Sanz
  • Patent number: 10253275
    Abstract: Disclosed is a method of treating a used hydrocarbon lubricant of ISO Viscosity Grade 46 or higher comprising oxidation products that adversely affect lubricant performance. The hydrocarbon lubricant has a Group II hydrocarbon oil or Group III hydrocarbon oil, optionally one or more lubricant additives, and an amount of varnish. The hydrocarbon lubricant is free of zinc-containing additives. The method comprises adding to the used hydrocarbon lubricant from about 2 percent by weight to about 20 percent by weight of a polyhydroxy polypropylene oxide homopolymer that has a hydroxyl number of from about 12 mg KOH/g to about 58 mg KOH/g as measured according to ASTM D4274.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: April 9, 2019
    Assignee: American Chemical Technologies, Inc.
    Inventor: Mark D. Latunski
  • Patent number: 9982149
    Abstract: The present invention provides a viscosity modifier composition including a compound (A) represented by the general formula (1) and a compound (B) represented by the general formula (2) at a mass ratio (A)/(B) of from 70/30 to 95/5, an emulsion composition and a water-based paint composition including the viscosity modifier composition.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: May 29, 2018
    Assignee: ADEKA CORPORATION
    Inventors: Masaki Hosaka, Takashi Ono
  • Patent number: 9765016
    Abstract: Compounds of formula (I) can modulate the activity of one or more S 1P receptors. Sphingosine 1-phosphate (S IP) is a lysophospholipid mediator that evokes a variety of cellular responses by stimulation of five members of the endothelial cell differentiation gene (EDG) receptor family, namely S1P1, S1P2, S1P3, S1P4, and S1P5 (formerly EDG1, EDG5, EDG3, EDG6 and EDG8). The EDG receptors are G-protein coupled receptors (GPCRs) and on stimulation propagate second messenger signals via activation of heterotrimeric G-protein alpha (Ga.) subunits and beta-gamma (G( )y) dimers.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: September 19, 2017
    Assignee: BIOGEN MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Xiaogao Liu, Bin Ma, Hairuo Peng
  • Patent number: 9617371
    Abstract: The invention relates to polyureas having a weight-average molecular weight ranging from 5,000 to 70,000 g/mol, the preparation thereof, and the use thereof as rheology control agents. The invention further relates to rheology control agents containing polyureas and to the use thereof. The invention moreover relates to formulations containing polyureas.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: April 11, 2017
    Assignee: BYK-Chemie GmbH
    Inventors: Daniela Leutfeld, Bianca Morhenn, Marc Eberhardt, Ina Kober, Jürgen Omeis, Sylvia Bühne, Berthold Jacobs
  • Patent number: 9284267
    Abstract: Urethanes are prepared by oxidative carbonylation of at least one amino compound in the presence of carbon monoxide, oxygen and organic, at least one hydroxyl-group-carrying compound. The carbonylation is carried out in the absence of halogen-containing promoters. The carbonylation is also carried out in the presence of a metal complex catalyst which contains neutral bidentate N-chelate ligands of the (N˜N) type, two monoanionic N,O-chelate ligands of the general type (N˜O)? or tetradentate dianionic chelate ligands (O˜N˜N˜O)2?.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: March 15, 2016
    Assignee: Bayer MaterialScience AG
    Inventors: Andreas Jacob, Stefan Wershofen, Stephan Klein, Jörg Sundermeyer, Fuming Mei
  • Patent number: 9150502
    Abstract: A method for producing urethane compounds includes allowing a primary amine, a urea and/or an N-unsubstituted carbamate, and an alcohol to react in the presence of a compound containing a noncoordinating anion and a metal atom as a catalyst.
    Type: Grant
    Filed: March 17, 2010
    Date of Patent: October 6, 2015
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Tetsuya Hamada, Mitsuaki Chida, Souta Itou, Yoshiki Shimokawatoko, Koichi Murayama, Hiroshi Takeuchi
  • Publication number: 20150148559
    Abstract: The invention provides new processes for making and purifying amino acid compounds, which are useful in the preparation of AKT inhibitors used in the treatment of diseases such as cancer, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 28, 2015
    Applicant: Genentech, Inc.
    Inventor: Travis Remarchuk
  • Publication number: 20150141417
    Abstract: Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.
    Type: Application
    Filed: May 14, 2012
    Publication date: May 21, 2015
    Inventors: Qingqi Chen, Rocio Alejandra Lopez, Jonathan Daniel Heller, Amanda Jean Morris
  • Patent number: 9012676
    Abstract: A preparation of aryl carbamates can be achieved readily by carbonylation of an aromatic polyamine compound with diphenyl carbonate (DPC) using a combination of an organic acid and a tertiary amine as a catalyst. Aryl carbamate can be converted into 4,4?-diphenylmethane diisocyanate (MDI) by heating it at about 200 to about 230° C. in a non-polar solvent containing inhibitor such as benzoyl chloride. In another application, trans-ureation of biscarbamates with an amine or mixed amines is found to be extremely facile in a polar solvent such as dimethyl sulfoxide (DMSO) and tetramethylene sulfone (TMS) in absence of any catalyst to make polyurea polymers of high molecular weights. Thus, efficient green-chemistry processes based on biscarbamates in making isocyanate products as well as urea prepolymers, urea elastomers and urea plastics have been developed in all in excellent yields without using reactive phosgene or 4,4?-diphenylmethane diisocyanate separately in the trans-ureation polymerizations.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: April 21, 2015
    Assignees: Great Eastern Resins Industrial Co., Ltd., National Chung Hsing University
    Inventors: Shenghong A. Dai, Hsueh-Yung Chen, Chao-Hsing Lin, Chun-Ying Huang, Wen-Chen Pan
  • Publication number: 20150087854
    Abstract: The present invention relates to a method of producing a carbamate compound, comprising reacting a fluorine-containing carbonic diester compound represented by formula (1) and a non-aromatic diamine compound represented by formula (2) without using a catalyst, to thereby produce a carbamate compound represented by formula (3), and a method of producing an isocyanate compound represented by formula (20) from the carbamate compound without using a catalyst, wherein R represents a fluorine-containing monovalent aliphatic hydrocarbon group, and A represents a divalent aliphatic hydrocarbon group, a divalent alicyclic hydrocarbon group or a divalent aromatic-aliphatic hydrocarbon group.
    Type: Application
    Filed: November 26, 2014
    Publication date: March 26, 2015
    Inventors: Takashi OKAZOE, Yuko Nagasaki, Hidekazu Okamoto
  • Patent number: 8946475
    Abstract: The present invention provides methods for preparing a polymeric compound of Formula I: or pharmaceutically acceptable salt thereof. The present invention also provides useful intermediates for preparing the compound of Formula I or pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: February 3, 2015
    Assignee: Cellceutix Corporation
    Inventors: Robert W. Kavash, Haizhong Tang, Carol Mulrooney, Dahui Liu
  • Patent number: 8927756
    Abstract: The present invention relates to a method of producing a carbamate compound, comprising reacting a fluorine-containing carbonic diester compound represented by formula (1) and a non-aromatic diamine compound represented by formula (2) without using a catalyst, to thereby produce a carbamate compound represented by formula (3), and a method of producing an isocyanate compound represented by formula (20) from the carbamate compound without using a catalyst, wherein R represents a fluorine-containing monovalent aliphatic hydrocarbon group, and A represents a divalent aliphatic hydrocarbon group, a divalent alicyclic hydrocarbon group or a divalent aromatic-aliphatic hydrocarbon group.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: January 6, 2015
    Assignee: Asahi Glass Company, Limited
    Inventors: Takashi Okazoe, Yuko Nagasaki, Hidekazu Okamoto
  • Publication number: 20140336252
    Abstract: The present invention provides compounds having the structure represented by general formula I, pharmaceutically acceptable salts thereofagonist, preparation methods therefor and a use thereof in the preparation of a medicine for the treatment of nervous system diseases. The compounds or pharmaceutical compositions thereof can be used as the KCNQ potassium channel agonist for treating nervous system diseases. Compared to retigabine, a compound in the prior art, the compound of the present invention have the same or better therapeutic effect, are easier for synthesis and storage, and less prone to oxidate deterioration.
    Type: Application
    Filed: October 23, 2012
    Publication date: November 13, 2014
    Inventors: Fajun Nan, Min Li, Zhaobing Gao, Fei Chen, Yangming Zhang, Pingzheng Zhou, Haining Hu, Haiyan Xu, Sheng Liu
  • Patent number: 8884047
    Abstract: The present invention provides a method for producing N-substituted carbamic acid-O-aryl ester derived from a compound having an ureido group, the method comprising the step of carrying out esterification or esterification and transesterification from the compound having the ureido group and a hydroxy composition containing one type or a plurality of types of hydroxy compounds.
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: November 11, 2014
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Nobuhisa Miyake, Masaaki Shinohata, Atsushi Okubo
  • Patent number: 8846971
    Abstract: The invention provides metal carbamates of the general formula (I) where R1 and R2 are each an alkyl group.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: September 30, 2014
    Assignee: BASF SE
    Inventors: Andreas Leitner, Robert Baumann, Wolfgang Siegel
  • Patent number: 8846809
    Abstract: A urethane adhesive composition includes a first liquid and a second liquid, the first liquid containing a prepolymer obtained by reacting a polyisocyanate and a high-molecular-weight polyol (I), and at least one filler selected from talc and calcium carbonate, and containing 20 parts by mass or more of talc, 0 to 40 parts by mass of calcium carbonate, and 10 parts by mass or more of zeolite based on 100 parts by mass of the polyisocyanate, the high-molecular-weight polyol (I), and the prepolymer in total, the second liquid containing a high-molecular-weight polyol (II) and a low-molecular-weight polyol, the ratio of the number of moles of hydroxyl groups derived from the low-molecular-weight polyol to the total number of moles of hydroxyl groups derived from the high-molecular-weight polyol (I) and the high-molecular-weight polyol (II) being four or more.
    Type: Grant
    Filed: September 10, 2008
    Date of Patent: September 30, 2014
    Assignee: Emulsion Technology Co., Ltd.
    Inventors: Yoshinori Igarashi, Koichiro Higasa
  • Patent number: 8846970
    Abstract: The invention provides metal carbamates of the general formula (I) where R1 and R2 are the same or different and are each an alkyl group having 1-18 carbon atoms and M is an alkali metal atom.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: September 30, 2014
    Assignee: BASF SE
    Inventors: Andreas Leitner, Robert Baumann, Wolfgang Siegel
  • Patent number: 8834857
    Abstract: A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: September 16, 2014
    Assignee: Nevada Naturals Inc.
    Inventors: Anthony E. Winston, Richard F. Stockel, Anthony Joseph Sawyer
  • Patent number: 8828098
    Abstract: Non-fluorinated blocked polyurethanes are described as extenders and, particularly as textile auxiliaries, for use with fluorochemical polymers in treating substrates, for example fibrous substrates, such as textile fabrics or yarns. The polyurethane is prepared by reacting a polyisocyanate, a blocking agent, and a non-fluorinated isocyanate reactive compound having an average alkyl chain length of 24 to 50 carbon atoms.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: September 9, 2014
    Assignee: 3M Innovative Properties Company
    Inventors: Stewart H. Corn, Chetan P. Jariwala
  • Patent number: 8816036
    Abstract: Catalysts, which are free of tin, are described which are useful in the reaction between an isocyanate and an alcohol, which is a key step for preparing polyurethane polymers. The catalyst is a metal complex or salt of formula (1): [Zn(L1)l1(L2)l2(Y)x]??(1) in which: l1?1 and l2=0 or 1; with l1+l2=2, x=1 or 2, the symbol L1 represents a ligand which is a ?-dicarbonylato anion or the enolate anion of a ?-dicarbonyl compound or an acetylacetato anion derived from a ?-ketoester, when l1=2, the symbols L1 are identical or different, the symbol L2 represents an anionic ligand which is different from L1, and the symbol Y represents a neutral ligand; where the metal complex or salt C of formula (1) is not zinc diacetylacetonate.
    Type: Grant
    Filed: October 12, 2009
    Date of Patent: August 26, 2014
    Assignee: Bluestar Silicones France SAS
    Inventors: Christian Maliverney, Laurent Saint-Jalmes
  • Patent number: 8796345
    Abstract: A method to form a urethane material, the method comprises blending and reacting at least one isocyanate, at least one isocyanate reactive compound and a metallized polyhedral oligomeric silsesquioxane to provide said urethane material, the metallized polyhedral oligomeric silsesquioxane is a dimeric structure with general formula wherein M represents a metal providing a 6-coordinated metal center, x and y being 1, R1O and R2O represent an alkoxide bridging the 6-coordinated metal centers, R3OH and R4OH represent an alcohol ligand and each of R5, to R18 is selected from the group consisting of alkyl-, polyether- and polyester ligands.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: August 5, 2014
    Assignee: Huntsman International LLC
    Inventors: Rene Alexander Klein, Christina Marinus, Chris Ian Lindsay, Hendrikus Abbenhuis, Jos Wilting, Gijsbert Gerritsen
  • Patent number: 8791223
    Abstract: Methods of catalyzing chemical reactions are provided. A tri-substituted phosphine having at least one substituent that is an alkyl group is added as a catalyst to reaction mixtures. Reaction mixtures contain uretdiones, anhydrides, or isocyanate functional materials including isocyanurates, in various combinations with hydroxyl, thiol, and/or amine functional materials. Curable compositions comprising these catalysts and reaction mixtures are also provided.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: July 29, 2014
    Assignee: PPG Industries Ohio, Inc.
    Inventors: Michael Zalich, Mark P. Bowman, Jonathan T. Martz, Stephen John Thomas, Gregory J. McCollum
  • Publication number: 20140194644
    Abstract: The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a rati
    Type: Application
    Filed: January 9, 2014
    Publication date: July 10, 2014
    Applicant: Asahi Kasei Chemicals Corporation
    Inventors: Masaaki Shinohata, Nobuhisa Miyake
  • Patent number: 8748412
    Abstract: Provided herein are non-peptide GLP-1 receptor modulator compounds, for example, of Formula I, pharmaceutical compositions comprising such compounds, and processes of preparation thereof. Also provided are methods of their use for the treatment of a metabolic disorder.
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: June 10, 2014
    Assignee: Argusina Bioscience Inc.
    Inventors: Jiayu Liao, Yufeng Hong, Yong Wang, Thomas W. Von Geldern, Kanyin E. Zhang
  • Patent number: 8729210
    Abstract: Prepolymers, which are accessible from formamides of low molecular weight di- or triamines (formamide-terminated low molecular weight compounds) and di- or polyisocyanates, of the general formula (II): X—[—N(CHO)—CO—NH—R1—NCO]n??(II) wherein X represents a linear or branched aliphatic, cycloaliphatic, heterocyclic and/or aromatic structural unit having 2 to 40 carbon atoms, and which is optionally further substituted and/or optionally comprises one or more heteroatoms, wherein R1 represents an organic radical which may optionally contain one or more heteroatoms and which may further contain one or more additional free isocyanate groups and/or one or more urethane, biuret, carbodiimide, isocyanurate, allophanate, iminooxadiazinedione and/or uretdione structural units, and wherein n?2; processes for making the same; compositions containing the same; and uses thereof.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: May 20, 2014
    Assignee: Bayer MaterialScience AG
    Inventors: Harald Blum, Evelyn Peiffer, Marc Leimenstoll
  • Publication number: 20140116292
    Abstract: The present invention relates to a cellulose acetate film used for optical compensation and a retardation enhancer used therein, and relates to a cellulose acetate film which has a high retardation value in the thickness direction (Rth).
    Type: Application
    Filed: June 20, 2012
    Publication date: May 1, 2014
    Applicant: SK INNOVATION CO., LTD.
    Inventors: Won Yeob Kim, Min Joung Im, Seung Eon Lee, Myoung Lae Kim, Yong Gyun Cho, Sang Yeup Lee, Ki Yup Kim
  • Publication number: 20140116293
    Abstract: The present invention relates to a cellulose acetate film for optical compensation and a retardation enhancer used therein, and relates to a cellulose acetate film which has a high retardation value in the thickness direction (Rth).
    Type: Application
    Filed: June 20, 2012
    Publication date: May 1, 2014
    Applicant: SK INNOVATION CO., LTD.
    Inventors: Won Yeob Kim, Min Joung Im, Seung Eon Lee, Hyo Shin Kwak, Myoung Lae Kim, Yong Gyun Cho
  • Patent number: 8703989
    Abstract: An object of the present invention is to provide a process for producing isocyanates, which are industrially useful compounds, without using phosgene, and to provide a process for chemically recycling waste polycarbonate resin. The present invention discloses a process enabling isocyanate compounds to be produced without using phosgene as a raw material by subjecting a carbamic acid ester compound obtained by a reaction between an aromatic polycarbonate resin and an amine compound to a thermal decomposition reaction, while at the same time disclosing a process enabling chemical recycling of aromatic polycarbonate resin by recovering a divalent aromatic hydroxy compound forming aromatic polycarbonates.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: April 22, 2014
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Masaaki Shinohata, Nobuhisa Miyake
  • Publication number: 20140057811
    Abstract: The present invention relates to compositions and methods for reducing or preventing the loss of drilling fluids and other well servicing fluids into a subterranean formation during drilling or construction of boreholes in said formation. Specifically, this invention comprises a curable composition capable of free radical polymerization for creating lost circulation material in-situ.
    Type: Application
    Filed: May 3, 2012
    Publication date: February 27, 2014
    Applicant: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Phillip S. Athey, Bernard E. Obi, Michael K. Poindexter
  • Patent number: 8653221
    Abstract: The invention relates to hydroxyl-functionalised polyurethane hot melt prepolymers comprising the chemical reaction product of isocyanate-reactive starting materials with at least one isocyanate-containing starting material. Said prepolymers are characterized in that the isocyanate-reactive starting materials of the hydroxyl-functionalised polyurethane hot melt prepolymers have a polypropylene glycol with a functionality higher than two and a number-average molar mass higher than or equal to 3,000 g/mol, a polypropylene glycol with a functionality less than or equal to two and a number-average molar mass less than or equal to 1,000 g/mol, and a chain lengthener with a functionality less than or equal to 500 g/mol, and the isocyanate-containing starting material of the hydroxyl-functionalised polyurethane hot melt prepolymer has an aliphatic or alicyclic diisocyanate.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: February 18, 2014
    Assignee: TESA SE
    Inventors: Uwe Schümann, Kirstin Weiland
  • Publication number: 20140031331
    Abstract: The present invention relates to aminotetraline derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline derivatives, and the use of such aminotetraline derivatives for therapeutic purposes. The aminotetraline derivatives are GlyT1 inhibitors.
    Type: Application
    Filed: September 19, 2013
    Publication date: January 30, 2014
    Inventors: Wilhelm Amberg, Michael Ochse, Udo Lange, Andreas Kling, Berthold Behl, Wilfried Hornberger, Mario Mezler, Charles W. Hutchins
  • Patent number: 8629231
    Abstract: An oligomer is made by capping a uretdione compound of structure with a compound (II) having an active hydrogen and a carbamate or cyclic carbonate group under conditions in which the isocyanate groups but not the uretdione group react. The product (III) is either reacted with a reactant having at least two active hydrogens under reaction conditions that cleave the uretdione ring, after which any cyclic carbonate groups may be converted to carbamate groups, or a product (III) having cyclic carbonate groups is reacted with ammonia or primary amine to provide uretdione with a hydroxy carbamate group that is then self-condensed under uretdione ring-opening conditions. A curable coating composition comprises the oligomer; a coated article is prepared by applying a layer of the curable coating composition and curing the applied layer.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: January 14, 2014
    Assignee: BASF Coatings GmbH
    Inventors: Nicholas Caiozzo, Walter H Ohrbom, David C Cranfill
  • Publication number: 20140012005
    Abstract: The present invention relates to a process for preparing chiral amino acids with excellent enantiomeric excesses.
    Type: Application
    Filed: December 22, 2011
    Publication date: January 9, 2014
    Applicant: Diverchim
    Inventors: Sylvain Darses, Nicolas Lefevre, Benoit Folleas, Jean-Louis Brayer
  • Patent number: 8614346
    Abstract: The invention provides methods and compositions for preparing amphetamine conjugates, such as lisdexamfetamine, homoarginine-D-amphetamine, and salts thereof. In one embodiment, the invention provides methods of preparing an amphetamine conjugate from a chloramphetamine intermediate.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: December 24, 2013
    Assignee: Cambrex Charles City, Inc.
    Inventors: Paul Alan Jass, Todd Jeffrey Johnson, Jason Scott Douglas, Matthew Wendell Schiesher
  • Patent number: 8609881
    Abstract: The present invention provides compound(s) selected from the group of compounds represented by structural Formula (I): wherein X, Y and R1 are as described herein, use of such compounds as anaerobic cure accelerators, and compostions including such compounds.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: December 17, 2013
    Assignee: Henkel IP US LCC
    Inventors: Andrew Messana, Anthony F. Jacobine, Steven Thomas Nakos, David M. Glaser
  • Patent number: 8604213
    Abstract: This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: December 10, 2013
    Assignee: Nutech Ventures
    Inventor: Stephen Dimagno
  • Publication number: 20130324717
    Abstract: This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.
    Type: Application
    Filed: August 5, 2013
    Publication date: December 5, 2013
    Inventors: Jason Clay Pearson, Max Allen Weaver, Jean Carroll Fleischer, Gregory Allan King
  • Publication number: 20130324718
    Abstract: This invention relates to processes and reagents for making diaryliodonium salts, which are useful for the preparation of fluorinated and radiofluorinated aromatic compounds.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 5, 2013
    Inventor: Stephen DiMagno
  • Patent number: 8598297
    Abstract: Prepolymers are prepared by a reaction of a polyisocyanate and a hydroxylmethyl containing polyester polyol derived from a fatty acid. The prepolymers can be prepared having isocyanate, hydroxyl, or a variety of other reactive functional groups. The prepolymers are useful in making polyurethanes and other polymers, or a crosslinking agents.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: December 3, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: Erdem Bedri, Debkumar Bhattacharjee, John N. Argyropoulos
  • Publication number: 20130303531
    Abstract: Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.
    Type: Application
    Filed: May 14, 2012
    Publication date: November 14, 2013
    Inventors: Qingqi Chen, Rocio Alejandra Lopez, Jonathan Daniel Heller, Amanda Jean Morris
  • Publication number: 20130281727
    Abstract: The invention provides metal carbamates of the general formula (I) where R1 and R2 are each an alkyl group.
    Type: Application
    Filed: June 18, 2013
    Publication date: October 24, 2013
    Inventors: Andreas LEITNER, Robert Baumann, Wolfgang Siegel
  • Publication number: 20130274502
    Abstract: The present invention provides methods for preparing a polymeric compound of Formula I: or pharmaceutically acceptable salt thereof. The present invention also provides useful intermediates for preparing the compound of Formula I or pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 19, 2012
    Publication date: October 17, 2013
    Applicant: PolyMedix, Inc.
    Inventors: Robert W. Kavash, Haizhong Tang, Carol Mulrooney, Dahui Liu
  • Patent number: 8557388
    Abstract: A polyurethane or polyurea coating for use in protecting a leading edge substrate on an airfoil against liquid or solid particle erosion, the composition made from an isocyanate-terminated prepolymer and curing agents, such as polyaspartic esters, aldimines and ketimines with optional flatting agent for matte coatings.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: October 15, 2013
    Assignee: Hontek Corporation
    Inventor: Shek C. Hong
  • Publication number: 20130244944
    Abstract: Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.
    Type: Application
    Filed: December 31, 2012
    Publication date: September 19, 2013
    Applicants: VERSITECH LIMITED, THE UNIVERSITY OF HONG KONG
    Inventors: Dan Yang, Xiang Li, Huiyan Zha
  • Publication number: 20130237626
    Abstract: The invention relates to radiation curable compositions comprising a liquid 0/s(acyl)phosphine photo initiators of formula (I): wherein each of Ar1, Ar2 and Ar3 is independently a substituted or unsubstituted aryl group. The invention also relates to stabilized forms of liquid bis(acyl)phosphines of formula (I) and radiation curable composition comprising said stabilized photoinitiators. The radiation curable compositions are selected from the group consisting of an optical fiber coating composition and a coating composition capable of radiation cure on concrete and a coating composition capable of radiation cure on metal.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 12, 2013
    Applicant: DSM IP Assets B.V.
    Inventors: Timothy Edward BISHOP, Edward Joseph Murphy, John Edmond Southwell, Satyendra Sarmah, TaiYeon Lee
  • Publication number: 20130231495
    Abstract: The invention provides metal carbamates of the general formula (I) where R1 and R2 are the same or different and are each an alkyl group having 1-18 carbon atoms and M is an alkali metal atom.
    Type: Application
    Filed: May 17, 2013
    Publication date: September 5, 2013
    Applicant: BASF SE
    Inventors: Andreas LEITNER, Robert Baumann, Wolfgang Siegel