Acylated Patents (Class 560/66)
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Patent number: 12228645Abstract: Provided is a sensor having a high SN ratio. The sensor includes a light source, a band pass filter; and a light-receiving element, in which the band pass filter includes a cholesteric liquid crystal layer that is a layer obtained by immobilizing a cholesteric liquid crystalline phase, the cholesteric liquid crystal layer has a region where a refractive index nx in an in-plane slow axis direction and a refractive index ny in an in-plane fast axis direction satisfy nx>ny, and in a case where a selective reflection wavelength of the cholesteric liquid crystal layer is represented by ?, the cholesteric liquid crystal layer has a second selective reflection peak at a wavelength ?/2 and a half-width of the second selective reflection peak at ?/2 is 30 nm or less.Type: GrantFiled: November 9, 2021Date of Patent: February 18, 2025Assignee: FUJIFILM CorporationInventors: Takao Taguchi, Yukito Saitoh, Hiroshi Sato, Katsumi Sasata, Akiko Watano
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Patent number: 11826469Abstract: Provided herein are methods of treatment, compositions, systems and kits using polymer particles as restraints of neutrophil function. Such methods include, but are not limited to, methods of preventing, treating, and/or ameliorating inflammatory diseases, infections, autoimmune diseases, malignant diseases, and other diseases or conditions in which neutrophils may be implicated. In some embodiments, polymer particles are useful for diagnosing neutrophil related diseases or conditions.Type: GrantFiled: September 22, 2021Date of Patent: November 28, 2023Assignee: The Regents of the University of MichiganInventors: Omolola Eniola-Adefeso, William Kelley, Theodore Standiford
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Patent number: 8742159Abstract: To provide a fluorinated compound having an RF group with at most 6 carbon atoms, whereby a fluorinated polymer having a highly durable water/oil repellency can be produced, and an environmental load is little, and a fluorinated polymer having a highly durable water/oil repellency and presenting little environmental load, obtainable by polymerizing such a fluorinated compound. A fluorinated compound represented by the following formula (I) and its polymer: CH2?C(M)COOXPhCOO(CH2)mCrF2r+1??(I) (in the formula (I), M is a hydrogen atom, a methyl group or a halogen atom, X is CHR1CH2O or CH2CHR1O, R1 is a C1-4 linear or branched alkyl group or CH2OR2, R2 is a C1-4 linear or branched alkyl group, Ph is a phenylene group, m is an integer of from 1 to 4, and r is an integer of from 1 to 6).Type: GrantFiled: September 14, 2012Date of Patent: June 3, 2014Assignee: Asahi Glass Company, LimitedInventor: Taiki Hoshino
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Publication number: 20140117284Abstract: A liquid crystal composition comprising a chiral dopant compound represented by the following structure (Structure 1): wherein: R1 and R2 are independently hydrogen, ā(C?O)R9, ā(C?O)R10, alkyl, aryl, alkaryl, alkenyl, cycloalkyl, alkoxyaryl, or heterocyclic all either substituted or unsubstituted, or combine to form a carbocyclic or heterocyclic ring; R3 is hydrogen, halogen, cyano, alkoxy, NHCOR9, NHSO2R9, COOR9, OCOR9, aryl, alkyl, alkenyl, cycloalkyl, or heterocyclic all either substituted or unsubstituted; R4 is hydrogen, alkyl, aryl, alkenyl, cycloalkyl, or heterocyclic all either substituted or unsubstituted; R5, R6, R7, and R8 are independently hydrogen, halogen, cyano, alkoxy, NHCOR9, NHSO2R9, COOR9, OCOR9, aryl, alkyl, alkenyl, cycloalkyl, alkoxyaryl or heterocyclic all either substituted or unsubstituted, or combine with each other, or R5 can combine with R4 to form a carbocyclic or heterocyclic ring; R9 and R10 are independently alkyl, alkoxy, aryl, naphthyl, styryl, alkenyl, cycloalkyl, alkoType: ApplicationFiled: January 6, 2014Publication date: May 1, 2014Applicants: KENT STATE UNIVERSITY, KENT DISPLAYS INCORPORATEDInventors: Donald R. Diehl, Erica N. Montbach
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Publication number: 20130281564Abstract: The present invention relates to novel photoactive polymer materials their use as orienting layer for liquid crystals, which are used for the production of non-structured and structured optical elements or electro-optical elements and multi-layer systems.Type: ApplicationFiled: December 21, 2011Publication date: October 24, 2013Applicant: ROLIC AGInventor: Hubert Seiberle
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Publication number: 20130037746Abstract: The present invention relates to an optical switch element, comprising a liquid-crystalline medium for the temperature-dependent regulation of radiant energy flow. The invention furthermore relates to the use of the optical switch element for the regulation of radiant energy flow between interior spaces and the environment and for the regulation of the temperature of interior spaces. The invention furthermore relates to a liquid-crystalline medium, characterised in that it comprises 5-95% of a compound of the formula (I), in particular for use in the optical switch elements according to the invention.Type: ApplicationFiled: March 31, 2011Publication date: February 14, 2013Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventor: Michael Junge
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Publication number: 20130035317Abstract: The invention relates to the use of di-aspirin (bis(2-carboxyphenyl)succinate) and its derivatives in the treatment of colon and colorectal cancer. It also relates to novel derivatives of di-aspirin and to a method of synthesis of the di-aspirin and its derivatives.Type: ApplicationFiled: February 15, 2011Publication date: February 7, 2013Inventors: Christopher John Perry, Iain Douglas Nicholl
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Publication number: 20130005924Abstract: To provide a fluorinated compound having an RF group with at most 6 carbon atoms, whereby a fluorinated polymer having a highly durable water/oil repellency can be produced, and an environmental load is little, and a fluorinated polymer having a highly durable water/oil repellency and presenting little environmental load, obtainable by polymerizing such a fluorinated compound. A fluorinated compound represented by the following formula (I) and its polymer: CH2?C(M)COOXPhCOO(CH2)mCrF2r+1??(I) (in the formula (I), M is a hydrogen atom, a methyl group or a halogen atom, X is CHR1CH2O or CH2CHR1O, R1 is a C1-4 linear or branched alkyl group or CH2OR2, R2 is a C1-4 linear or branched alkyl group, Ph is a phenylene group, m is an integer of from 1 to 4, and r is an integer of from 1 to 6).Type: ApplicationFiled: September 14, 2012Publication date: January 3, 2013Applicant: Asahi Glass Company, LimitedInventor: Taiki HOSHINO
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Patent number: 8288436Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.Type: GrantFiled: April 17, 2008Date of Patent: October 16, 2012Assignee: Cognis IP Management GmbHInventor: Markus Dierker
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Patent number: 8283314Abstract: Dermatological and cosmetic compositions and methods are provided to reduce the appearance of biological and/or environmentally-caused aging.Type: GrantFiled: July 2, 2008Date of Patent: October 9, 2012Assignee: Jan Marini Skin Research, Inc.Inventor: Jan Marini
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Publication number: 20120059185Abstract: The present invention discloses a process for producing a polyether-polyester block copolymer with a di(C 1-C 4)alkyl ester of aromatic dicarboxylic acid, an aliphatic diol or aliphatic polyol and a polyether having at least one terminal hydroxyl group in an inert solvent. In the present invention, the inert solvent 5 is used to prevent the di(C 1-C 4)alkyl ester of aromatic dicarboxylic acid from sublimation instead of excessive polyol, such that the subsequent removal of excessive polyol under high temperature and high vacuum is avoided.Type: ApplicationFiled: July 1, 2009Publication date: March 8, 2012Applicant: Rhodia (China) Co., Ltd.Inventors: Zhaoqing Liu, Daobing Lin, Qiaobo Li
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Publication number: 20120059117Abstract: It comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. It also comprises the processes for preparing the compounds and the polymers, as well as to the use of these polymers for the manufacture of medical devices.Type: ApplicationFiled: May 9, 2011Publication date: March 8, 2012Inventors: Lluis Duocastella Codina, Maria Molina, Ofir Arad, Jose Ignacio Borrell Bilbao, David Sanchez Garcia, Sofia Henriette Pettersson Salom
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Patent number: 8080683Abstract: An electrochromic compound represented by the following General Formula (1). A-(CX2)nāB??General Formula (1) In the formula, A is a monovalent binding group, B is a redox chromophore, X is a halogen atom, and n is an integer of 1 or more.Type: GrantFiled: March 10, 2009Date of Patent: December 20, 2011Assignee: Ricoh Company, Ltd.Inventors: Takeshi Shibuya, Shigenobu Hirano, Hiroshi Kondo, Yuki Nakamura, Yukiko Abe, Tohru Yashiro
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Publication number: 20110181826Abstract: The present invention relates to a radial-shaped liquid crystal compound, and an optical film and a liquid crystal display device comprising the same. Particularly the present invention provides a compound represented by Chemical Formula 1 comprising a radial-shaped core of tetraphenyl ethylene in which four phenyl groups are bonded to an ethylene group, and makes it possible to provide an optical film which can minimize the change of color according to viewing angle and has an improved contrast ratio and high refractive anisotropy, and a liquid crystal display device comprising the same, by using the compound.Type: ApplicationFiled: July 3, 2009Publication date: July 28, 2011Applicant: LG Chem, Ltd.Inventors: Bum-Gyu Choi, Min-Jin Ko, Myung-Sun Moon, Jae-Ho Cheong, Dae-Ho Kang, Ki-Youl Lee, Yun-Bong Kim
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Publication number: 20110152210Abstract: Synthetic polyphenolic compounds of formula (I), their modes of synthesis, and pharmaceutical compositions thereof are provided herein. Use of the compounds and compositions described herein for inhibiting proteasomal activity and for treating cancer is also provided.Type: ApplicationFiled: December 15, 2010Publication date: June 23, 2011Applicants: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/McGILL UNIVERSITY, THE HONG KONG POLYTECHNIC UNIVERSITY, WAYNE STATE UNIVERSITYInventors: Tak-Hang CHAN, Q. Ping DOU
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Publication number: 20110143943Abstract: The present invention relates to novel C2-phenyl-substituted cyclic ketoenols of the formula (I) in which W, X, Y, Z and CKE are as defined in the description, to processes for their preparation and to their use as pesticides and herbicides.Type: ApplicationFiled: February 17, 2011Publication date: June 16, 2011Applicant: Bayer AktiengesellschaftInventors: Michael RUTHER, Hermann Hagemann, Udo Schneider, Markus Dollinger, Peter Dahmen, Ulrike Wachendorff-Neumann, Reiner Fischer, Alan Graff, Thomas Bretschneider, Christoph Erdelen, Mark Wilhelm Drewes, Dieter Feucht, Folker Lieb
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Publication number: 20100267858Abstract: A dichroic guest-host polarizer comprises an oriented polymerized liquid crystal host and aligned therewith a dichroic guest. The dichroic ratio of the polarizer is about 15 or more. The polarizer may have a small thickness, be manufactured using a wet deposition method, optionally in accordance with a desired pattern, and be provided on the inside of a liquid crystal cell. Polymerizable liquid crystals having a highly ordered mesophase which may be suitable used to obtain highly oriented polymer films such as polarizer films are disclosed.Type: ApplicationFiled: July 2, 2010Publication date: October 21, 2010Inventors: Johan LUB, Emiel Peeters, Dirk Jan Broer
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Publication number: 20100120910Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.Type: ApplicationFiled: April 17, 2008Publication date: May 13, 2010Applicant: COGNIS IP MANAGEMENT GMBHInventor: Markus Dierker
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Patent number: 7462361Abstract: The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.Type: GrantFiled: August 17, 2004Date of Patent: December 9, 2008Assignee: Novabay Pharmaceuticals, Inc.Inventors: Mansour Bassiri, Ramin Najafi, Lu Wang, Jane Yang
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Patent number: 7456136Abstract: A linear compound and a metal salt or boron-containing metal salt thereof contains one or more carboxyl-containing phenol units or derivatives thereof and one or more on average at least C18 hydrocarbyl-substituted hydroxyaromatic units or derivatives thereof connected by one or more divalent bridging groups. A concentrate contains the linear compound or metal salt thereof and an organic diluent. A lubricating oil composition contains a minor amount of the linear compound or metal salt thereof and a major amount of a lubricating oil. Additional embodiments of the invention are processes to make the linear compound and the metal salt thereof.Type: GrantFiled: August 21, 2002Date of Patent: November 25, 2008Assignee: The Lubrizol CorporationInventors: David J. Moreton, Stephen J. Cook, David Cressey
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Patent number: 7445789Abstract: New biocompatible polymeric systems carrying triflusal or HTB are described which result from the polymerization of a monomer A of the acrylic or vinylic type and carrying triflusal or HTB, wherein triflusal or HTB are linked to the remainder of the molecule of said monomer through an in vivo hydrolysable covalent bond, and optionally a second polymerisable monomer B. These new polymeric systems are useful as coating for synthetic biomaterials.Type: GrantFiled: November 7, 2005Date of Patent: November 4, 2008Assignee: Palau Pharma, S.A.Inventors: Alberto Gallardo Ruiz, Gema Rodriguez Crespo, Julio San RomƔn del Barrio
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Patent number: 7358383Abstract: The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.Type: GrantFiled: January 26, 2004Date of Patent: April 15, 2008Assignees: University of South Florida, McGill University, The Hong Kong Polytechnic UniversityInventors: Q. Ping Dou, Tak-Hang Chan, David M. Smith
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Patent number: 7358384Abstract: When a salt of an amine and an optically active diacyltartaric acid, or a diastereomer salt of an optically active amine and an optically active diacyltartaric acid, obtained by optically resolving a racemic amine using the optically active diacyltartaric acid, is salt-exchanged with an acid aqueous solution, the optically active diacyltartaric acid is added in the acid aqueous solution beforehand. Furthermore, a raw material containing a racemic amine and an optically active diacyltartaric acid is optically resolved, and the diastereomer salt of the optically active amine and the optically active diacyltartaric acid respectively of one isomer type, is separated. The obtained diastereomer salt is dissociated using an acid aqueous solution containing the optically active diacyltartaric acid, for recovering the optically active diacyltartaric acid, and the obtained optically active diacyltartaric acid is recycled into an optical resolution step as a raw material of the optical resolution step.Type: GrantFiled: December 22, 2003Date of Patent: April 15, 2008Assignee: Toray Fine Chemicals Co., Ltd.Inventors: Seiji Morii, Toshihiro Fujino, Haruyo Sato
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Patent number: 7238831Abstract: Novel platform mesogens, intermediates, and polymerizable mesogens made therefrom.Type: GrantFiled: January 23, 2002Date of Patent: July 3, 2007Assignee: Southwest Research InstituteInventors: Stephen T. Wellinghoff, Douglas P. Hanson
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Patent number: 7049308Abstract: A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less than about 25, is useful as an NO donor. When the compound is obtained from a carbon acid with a pKa less than about 10, it provides vascular relaxing effect when used at micromolar concentrations and this activity is potentiated by glutathione to be obtained at nanomolar concentrations. When the compound is obtained from a carbon acid with a pKa ranging from about 15 to 20, vascular relaxing effect is obtained at nanomolar concentrations without glutathione. In another embodiment, a biocompatible polymer incorporates a C-nitroso moiety.Type: GrantFiled: September 27, 2001Date of Patent: May 23, 2006Assignee: Duke UniversityInventors: Jonathan S. Stamler, Eric J. Toone
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Publication number: 20040266999Abstract: A method for extracting a hydrophobic group-containing water-soluble organic compound, comprising the step of bringing an aqueous solution containing the hydrophobic group-containing water-soluble organic compound and a saccharide into contact with a polar organic solvent to obtain an aqueous phase and an organic phase, whereby the hydrophobic group-containing water-soluble organic compound is transferred to the organic phase. The saccharide concentration of the aqueous solution may be at least 12 g per 100 ml of the aqueous solution. The aqueous solution may further contain a phase separation assisting agent. The phase separation assisting agent may be selected from the group consisting of sodium chloride, sodium citrate, magnesium sulfate, and ammonium sulfate.Type: ApplicationFiled: August 19, 2004Publication date: December 30, 2004Inventors: Takashi Kuriki, Takahisa Nishimura, Kazuhisa Sugimoto
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Publication number: 20040199004Abstract: Mesogens having the following general formula: 1Type: ApplicationFiled: March 26, 2004Publication date: October 7, 2004Applicant: Southwest Research InstituteInventors: Stephen T. Wellinghoff, Douglas P. Hanson
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Publication number: 20040186167Abstract: The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.Type: ApplicationFiled: January 26, 2004Publication date: September 23, 2004Inventors: Q. Ping Dou, Tak-Hang Chan, David M. Smith
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Publication number: 20040186027Abstract: A linear compound and a metal salt or boron-containing metal salt thereof contains one or more carboxyl-containing phenol units or derivatives thereof and one or more on average at least C18 hydrocarbyl-substituted hydroxyaromatic units or derivatives thereof connected by one or more divalent bridging groups. A concentrate contains the linear compound or metal salt thereof and an organic diluent. A lubricating oil composition contains a minor amount of the linear compound or metal salt thereof and a major amount of a lubricating oil. Additional embodiments of the invention are processes to make the linear compound and the metal salt thereof.Type: ApplicationFiled: February 19, 2004Publication date: September 23, 2004Inventors: David J Moreton, Stephen J Cook, David Cressey
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Publication number: 20040152629Abstract: The present invention relates to stilbene and quinone compounds related to combretastatin A-4 and their use as anticancer compounds and prodrugs. The compounds include those with an alkyl group on the double bond of cis or trans-stilbenes, compounds with one or more (and preferably 2 or 3) alkyl group substituents on the stilbene A ring, compounds with an alkoxy group other than methoxy at position 3, 4, and/or 5 of the stilbene A ring, compounds (or prodrugs) in which BOC amino acid esters are formed with the phenolic hydroxyl at the 3-position of the B ring and compounds (or prodrugs) based on a benzoquinone B ring. The present invention further relates to the photochemical reactions of stilbene compounds, either the above compounds disclosed for the first time herein or compounds based on prior art stilbenes.Type: ApplicationFiled: March 3, 2004Publication date: August 5, 2004Inventors: John Anthony Hadfield, Alan Thomson McGown, Stephen Patrick Mayalarp, Edward John Land, Ian Hamblett, Keira Gaukroger, Nicholas James Lawrence, Lucy Annette Hepworth, John Butler
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Patent number: 6753442Abstract: Compounds of formula A—X1—ONO2 (I) in a partially or completely amorphous form and pharmaceutical compositions thereof.Type: GrantFiled: December 17, 2001Date of Patent: June 22, 2004Assignee: Nicox S.A.Inventors: Francesca Benedini, Patrizia Antognazza
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Publication number: 20030180691Abstract: Novel unsaturated esters for use in dentistry as bonding agents are produced by a reaction of a cyclic dianhydride with unsaturated alcohols.Type: ApplicationFiled: February 7, 2002Publication date: September 25, 2003Inventors: Martin Hamer, Byoung In Suh, Amer Tiba
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Publication number: 20030176726Abstract: This invention relates to new RAR selective retinoid agonists of formula I 1Type: ApplicationFiled: December 19, 2002Publication date: September 18, 2003Inventors: Paula Nanette Belloni, Michael Klaus, Jean-Marc Lapierre
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Patent number: 6596193Abstract: To improve switching times, especially at low temperatures, one or more reactive liquid crystalline compounds is added to a liquid crystal mixture used in an electrooptical system. The electrooptical system comprises a PDLC film comprising a liquid crystal mixture forming micro- droplets in an optically isotropic, transparent polymer matrix between 2 electrode layers. The reactive liquid crystalline compounds are of formula II, R′—G′—R″, wherein R′, G′ and R″ are as defined herein. The liquid crystal mixture comprises one or more compounds of the formula I wherein R, A1, A2, Z1, Z2, X1, X2, Q, Y and n are as defined herein.Type: GrantFiled: May 8, 2002Date of Patent: July 22, 2003Assignee: Merck Patent GmbHInventors: David Coates, Owain Llyr Parri, Simon Greenfield, Martin David Tillin, Mark John Goulding, Patrick Nolan
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Patent number: 6565769Abstract: To improve switching times, especially at low temperatures, one or more reactive liquid crystalline compounds is added to a liquid crystal mixture used in an electrooptical system. The electrooptical system comprises a PDLC film comprising a liquid crystal mixture forming micro- droplets in an optically isotropic, transparent polymer matrix between 2 electrode layers, one of the refractive indices of the liquid crystal mixture is matched to the refractive index of the polymer matrix, the PDLC film exhibits an electrically switching transparency essentially independent of the polarization of the incident light, the precursor of the PDLC film comprises one or more monomers, oligomers and/or prepolymers and a photoinitiator, and is cured photoradically, the liquid crystal mixture comprises one or more compounds of the formula I wherein R, A1, A2, Z1, Z2, X1, X2, Q, Y and n are as defined herein.Type: GrantFiled: December 29, 2000Date of Patent: May 20, 2003Assignee: Merck Patent GmbHInventors: David Coates, Owain Llyr Parri, Simon Greenfield, Martin David Tillin, Mark John Goulding, Patrick Nolan
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Publication number: 20030028048Abstract: A compound is of formula (I), in which: A1 to A4, E1 and E2 each independently represent hydrogen or an optionally-substituted hydrocarbon group; B1 and B2 each independently represent a single bond, an oxygen atom or an optionally-substituted hydrocarbon group; MG1 and MG2 each independently represent an optionally-substituted ring system; CG is a divalent or polyvalent chiral group. The optically active compound may be used as a doping agent for liquid crystals for a wide range of applications including solid state cholesteric filters for projection displays, circular polarisers, optical filters, etc.Type: ApplicationFiled: June 20, 2002Publication date: February 6, 2003Inventors: Zoubair Mohammed Cherkaoui, Klaus Schmitt
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Patent number: 6475574Abstract: The present invention generally relates to a direactive compound which is of the formula IV A R1—(CH2)mO—MG—O—(CH2)n—R2 (IVA) wherein R1, R2, m, n, and MG are defined herein.Type: GrantFiled: May 22, 2000Date of Patent: November 5, 2002Assignee: Merck Patent Geselleschaft mit beschranhkter HaftungInventors: David Coates, Simon Greenfield
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Patent number: 6458757Abstract: The present invention relates to a process for the production of perfuming compositions, to perfumed products, and to products obtained therefrom. More specifically, the present invention concerns a process for the production of perfuming compositions, perfumed products and substances for perfumery characterized in that they comprise, as an active ingredient with an influence on the scent, an effective quantity of an alkylsalicylic acid ester.Type: GrantFiled: April 24, 1998Date of Patent: October 1, 2002Inventor: Isabelle Storet
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Patent number: 6383499Abstract: A topical medicament for the treatment of psoriasis comprises metallic iodine, virgin wax, a variety of oils of animal and plant origin, camphor, chlorophyll and benzoic acid in a pharmaceutically acceptable emollient excipient base.Type: GrantFiled: February 26, 2001Date of Patent: May 7, 2002Assignee: Curacid America CorporationInventor: Ramon Efrain Vasquez Lipi
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Patent number: 6369188Abstract: Polyfunctional polymerizable urethane- or urea-containing oligomers allow the design, adjustment, and regulation of chemical and physical properties of the described oligomers. The invention discloses the formulas and compositions of these oligomers, methods of their synthesis, and methods of converting the described oligomers into useful polymeric products. The described oligomers can be used for many purposes, both directly and in combination with other chemicals in multiple applications such as adhesives, sealants, coatings, composites, etc., as well as in castable and moldable materials.Type: GrantFiled: March 27, 1999Date of Patent: April 9, 2002Assignee: Polymeright, Inc.Inventors: Leonid Rappoport, Alex Vainer, Aleksandr Yam
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Patent number: 6369262Abstract: Rigid-rod monomers and polymers are provided for use in applications such as rapid prototyping, composites and adhesives. The monomers can be photocured through the end groups and then thermally post cured through the acetylene groups. The result is a highly crosslinked polymer having an effective glass transition temperature well above 200° C.Type: GrantFiled: March 10, 1999Date of Patent: April 9, 2002Assignee: University of DaytonInventors: Richard P. Chartoff, Jayprakash C. Bhatt, Tat H. Tong
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Publication number: 20020026060Abstract: New compounds containing bicyclic fused rings, one of which being a phenyl moiety connected by an aliphatic chain to a cycloalkyl or aryl moiety, and pharmaceutically active salts thereof are useful as RAR selective retinoid agonists. Furthermore, such retinoic acid receptor agonists, particularly retinoic acid receptor &ggr; (RAR&ggr;) selective agonists, are useful for the treatment of emphysema and associated pulmonary diseases, as well as for the therapy and prophylaxis of dermatological disorders, for the therapy and prophylaxis of malignant and premalignant epithelial lesions, tumors and precancerous changes of the mucous membrane in the mouth, tongue, larynx, esophagus, bladder, cervix and colon.Type: ApplicationFiled: April 23, 2001Publication date: February 28, 2002Inventors: Paula Nanette Belloni, Synese Jolidon, Michael Klaus, Jean-Marc Lapierre
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Patent number: 6344558Abstract: 1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions.Type: GrantFiled: April 20, 2001Date of Patent: February 5, 2002Assignee: Gruenthal GmbHInventors: Helmut Buschmann, Wolfgang Strassburger, Elmar Friderichs
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Patent number: 6262293Abstract: &ohgr;-Cycloalkyl-prostaglandin E2 derivatives of formula (I) (wherein all symbols are as defined in the description); and non-toxic salts thereof, prodrugs thereof and cyclodextrin clathrates thereof. Compounds of formula (I) strongly bind on the EP2 subtype receptor. Therefore, they are useful for prevention and/or treatment of immunological diseases (autoimmune diseases, organ transplantation etc.), asthma, abnornmal bone formation, neuronal cell death, liver damage, abortion, premature birth or retina neuropathy of glaucoma etc.Type: GrantFiled: June 23, 2000Date of Patent: July 17, 2001Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Kousuke Tani, Shuichi Ohuchida
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Patent number: 6248737Abstract: 1-phenyl-3 -dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions.Type: GrantFiled: June 6, 1995Date of Patent: June 19, 2001Assignee: Gruenenthal GmbHInventors: Helmut Buschmann, Wolfgang Strassburger, Elmar Friderichs
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Patent number: 6110955Abstract: This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating cutaneous ulcers, treating gastrointestinal disorders, treating blood disorders such as anemias, immunomodulation, enhancing recombinant gene expression, treating insulin-dependent patients, treating cystic fibrosis patients, inhibiting telomerase activity, treating virus-associated tumors, especially EBV-associated tumors, modulating gene expression and particularly augmenting expression of a tumor suppressor gene, inducing tolerance to an antigen and treating, ameliorating or preventing protozoan infection. The methods of the invention use metabolically stabilized oxyalkylene esters.Type: GrantFiled: March 11, 1997Date of Patent: August 29, 2000Assignee: Beacon Laboratories, Inc.Inventors: Abraham Nudelman, Ada Rephaeli, Edward Neiss, Bernard Loev
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Patent number: 6020522Abstract: A methyl group-containing aromatic compound having a phenolic hydroxyl group protected by a protecting group, is oxidized with oxygen to provide an aromatic hydroxycarboxylic acid derivative. The protecting group includes, for example, an acyl group.Type: GrantFiled: May 11, 1998Date of Patent: February 1, 2000Assignee: Daicel Chemical Industries, Ltd.Inventors: Yasutaka Ishii, Tatsuya Nakano
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Patent number: 6002042Abstract: A liquid crystal compound represented by the following general formula (1): ##STR1## wherein R is a linear alkyl group having 6 to 12 carbon atoms, X and Y are both a hydrogen atom, or one of them is a hydrogen atom and the other is a fluorine atom, m is an integer of 0 to 5, n is an integer of 1 to 5, and C* is an asymmetric carbon atom. Since the liquid crystal compounds of the present invention have an anti-ferroelectric phase or a ferrielectric phase and the anti-ferroelectric phase or a ferrielectric phase has a highly practical phase sequence and wide temperature range, they are of great industrial value.Type: GrantFiled: January 13, 1998Date of Patent: December 14, 1999Assignee: Mitsubishi Gas Chemical Company, Inc.Inventors: Takakiyo Mine, Tomoyuki Yui, Masahiro Johno, Yuki Motoyama, Hiroshi Mineta
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Patent number: 5939586Abstract: A process for the production of an intermediate for a liquid crystal compound, which comprises reacting an alkyloxybiphenylcarboxylic acid with purified thionyl chloride substantially free of sulfuryl chloride, the thionyl chloride being obtained by adding phenol, etc., to thionyl chloride, heating the mixture and distilling the resultant mixture; and a process for the production of a liquid crystal compound from the above intermediate. According to the present invention, thionyl chloride can be easily purified, and a liquid crystal compound having a very high purity can be obtained by the use of the purified thionyl chloride.Type: GrantFiled: October 31, 1997Date of Patent: August 17, 1999Assignee: Mitsubishi Gas Chemical Company, Inc.Inventors: Hiroshi Mineta, Tomoyuki Yui
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Patent number: RE39593Abstract: 1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions.Type: GrantFiled: June 17, 2003Date of Patent: April 24, 2007Assignee: Gruenenthal GmbHInventors: Helmut Buschmann, Wolfgang Strassburger, Elmar Friderichs