Ester Function Attached Directly To A Ring Patents (Class 560/64)
  • Patent number: 10913729
    Abstract: Described are specific mixtures comprising one or more (cannabinoid) compounds of the formula (A) and/or one or more of their salts as well was methods for their production. Further described are a compound of the formula (A), a salt of the formula (A) and a corresponding mixture for use as a medicament or, respectively, for use in a method for therapeutic treatment of the human or animal body. Described are also corresponding pharmaceutical formulations, cosmetic preparations and preparations for pleasure and/or nutrition, suitable for consumption, as well as methods for producing CBDV and THCV.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: February 9, 2021
    Assignee: SYMRISE AG
    Inventors: Oskar Koch, Marcus Rudolf Götz
  • Patent number: 9505907
    Abstract: An ester composition including terephthalate compounds substituted with a non-hybrid and non-branched alkyl group, a hybrid and branched alkyl group, and a non-hybrid and branched alkyl group, respectively by 0.5 wt % to 9.5 wt %, by 14.5 wt % to 43.8 wt %, and 46.7 wt % to 85 wt % based on the total weight of the ester composition, a method of preparing the same, and a resin composition including the same are provided. The ester composition has a short absorption time with respect to the resin and short fusion time and improves the processability of the resin composition. In addition, good physical properties may be provided when manufacturing a sheet and a compound such as a cable, an interior of a car, a film, a sheet, a tube, a wallpaper, a toy, a flooring material, and the like.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: November 29, 2016
    Assignee: LG Chem, Ltd.
    Inventors: Hyun Kyu Kim, Mi Yeon Lee, Dong Hyun Ko, Chil Eui Hong, Gyu Il Lee
  • Patent number: 9328050
    Abstract: This invention relates to hydrogenation processes for making hydroxymethylbenzoic acid compounds. More specifically, this invention relates to hydrogenation processes in the presence of tertiary amide solvent compounds, as well as compositions that can result from such processes. The invention thus provides processes for making hydroxymethylbenzoic acid compounds.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: May 3, 2016
    Assignee: Eastman Chemical Company
    Inventors: Venkata Bharat Ram Boppana, Robert Thomas Hembre, Scott Donald Barnicki, Shane Kipley Kirk
  • Patent number: 9187401
    Abstract: The invention relates to a process for preparing a compound represented by the formula 1 which compound may optionally be further mono- or di- substituted with halogen atoms, alkyl groups having 1 to 4 C— atoms and/or alkoxy groups having 1 to 4 C— atoms, wherein R is methyl or ethyl group, comprising the step of: contacting a corresponding compound represented by the formula 2 which compound is not further substituted or further mono- or di- substituted in corresponding positions with halogen atoms, alkyl groups having 1 to 4 C— atoms and/or alkoxy groups having a to 4 C-atoms, with an alkylating agent, wherein the alkylating agent is a compound of the formula (RO)2SO2 or RX, wherein R has the above meaning and X is halogen, in the presence of a bis-quaternary ammonium salt or a polymeric quaternary ammonium salt, in a two-phase system of an aqueous solution of a base and an organic solvent.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: November 17, 2015
    Assignee: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Syed Azhar Hashmi, Flaiyh Al-Anazi
  • Patent number: 9000209
    Abstract: A method of synthesis of para-substituted benzoate esters and acids is provided, wherein the para-substituted regioisomer is obtained substantially free of the meta-substituted impurity, the method comprising contacting a coumalate ester or acid and an unactivated alkene at elevated temperature in the presence of a metal oxidation catalyst and an oxidant. The metal oxidation catalyst can be palladium, such as palladium on carbon, and the oxidant can be the oxygen gas in ambient air. The reaction can be carried out without solvent or in high boiling hydrocarbon solvents such as mesitylene. When the unactivated alkene is a monosubstituted alkene, yields of at least about 50 or 60% of para-substituted ester and acid products, respectively, are obtained, substantially free of the regioisomeric meta-substituted impurity.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: April 7, 2015
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: George A. Kraus
  • Patent number: 8962541
    Abstract: The present invention relates to alcohols and in particular to C4 to C15 alcohols that are used in the production of esters.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: February 24, 2015
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Allen D. Godwin, Philippe L. Buess, Raphael F. Caers, Arie Van Vliet, Eddy T. A. Van Driessche, Alfons Cuyckens
  • Patent number: 8920524
    Abstract: Disclosed are polyisobutenyl alcohols and substituted polyisobuentyl alcohols of the formula: wherein n is an integer from 5 to 90, R is selected from the group consisting of hydrogen, haloalkyl, alkoxycarbonyl and substituted aryl wherein at least one substituent group of the substituted aryl is selected from cyano, nitro and alkoxycarbonyl.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: December 30, 2014
    Assignee: Chevron Oronite Company LLC
    Inventors: Richard E. Cherpeck, Ruth Smocha
  • Patent number: 8846292
    Abstract: A radiation-sensitive composition containing a resist compound having a high sensitivity, a high resolution, a high etching resistance, and a low outgas which forms a resist pattern with good shape and a method of forming a resist pattern and novel compositions for forming a photoresist under coat film which is excellent in optical properties and etching resistance and contains substantially no sublimable substance and an under coat film formed by the composition. Radiation-sensitive composition containing a solvent and a cyclic compound having, e.g., a cyclic compound (A) having a molecular weight of 700 to 5000 which is synthesized by the condensation reaction of a compound having 2 to 59 carbon atoms and 1 to 4 formyl groups with a compound having 6 to 15 carbon atoms and 1 to 3 phenolic hydroxyl groups, and a cyclic compound for use in the radiation-sensitive composition.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: September 30, 2014
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Masatoshi Echigo, Dai Oguro
  • Patent number: 8846972
    Abstract: The invention relates to fatty acid acylated salicylate derivatives; compositions comprising an effective amount of a fatty acid acylated salicylate derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a fatty acid acylated salicylate derivative.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: September 30, 2014
    Assignee: Catabasis Pharmaceuticals, Inc.
    Inventors: Chi B. Vu, Jean E. Bemis, Michael R. Jirousek, Jill C. Milne, Jesse J. Smith
  • Publication number: 20140288324
    Abstract: A method of synthesis of para-substituted benzoate esters and acids is provided, wherein the para-substituted regioisomer is obtained substantially free of the meta-substituted impurity, the method comprising contacting a coumalate ester or acid and an unactivated alkene at elevated temperature in the presence of a metal oxidation catalyst and an oxidant. The metal oxidation catalyst can be palladium, such as palladium on carbon, and the oxidant can be the oxygen gas in ambient air. The reaction can be carried out without solvent or in high boiling hydrocarbon solvents such as mesitylene. When the unactivated alkene is a monosubstituted alkene, yields of at least about 50 or 60% of para-substituted ester and acid products, respectively, are obtained, substantially free of the regioisomeric meta-substituted impurity.
    Type: Application
    Filed: June 21, 2012
    Publication date: September 25, 2014
    Inventor: George A. Kraus
  • Publication number: 20140275604
    Abstract: The invention relates to a process for preparing a compound represented by the formula 1 which compound may optionally be further mono- or di- substituted with halogen atoms, alkyl groups having 1 to 4 C- atoms and/or alkoxy groups having 1 to 4 C- atoms, wherein R is methyl or ethyl group, comprising the step of: contacting a corresponding compound represented by the formula 2 which compound is not further substituted or further mono- or di- substituted in corresponding positions with halogen atoms, alkyl groups having 1 to 4 C- atoms and/or alkoxy groups having a to 4 C- atoms, with an alkylating agent, wherein the alkylating agent is a compound of the formula (RO)2SO2 or RX, wherein R has the above meaning and X is halogen, in the presence of a bis-quaternary ammonium salt or a polymeric quaternary ammonium salt, in a two-phase system of an aqueous solution of a base and an organic solvent.
    Type: Application
    Filed: October 8, 2012
    Publication date: September 18, 2014
    Inventors: Syed Azhar Hashmi, Flaiyh Al-Anazi
  • Publication number: 20140221394
    Abstract: The invention provides an acid addition salt of a compound of the formula (1). Also provided by the invention are processes for preparing the compound of formula (1) and alkyl analogues thereof, novel intermediates for use in the process and methods for preparing the intermediates. The invention also provides new medical uses of compounds of the formula (1) and its ethyl analogue.
    Type: Application
    Filed: January 7, 2014
    Publication date: August 7, 2014
    Applicant: Astex Therapeutic Ltd.
    Inventors: Martyn Frederickson, John Francis Lyons, Neil Thomas Thompson, Mladen Vinkovic, Brian John Williams, Andrew James Woodhead, Alison Jo-Anne Woolford
  • Patent number: 8722846
    Abstract: The composition of a homopolymer of (phosphonyl) aromatic diester compound using a catalyst and a glycol is provided. Further, the composition of a copolymer of the (phosphonyl) aromatic diester compound using a catalyst, a glycol and a second diester is provided. These polymers find application as flame retardants during synthesis of various polymeric materials.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: May 13, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Neville Everton Drysdale, Fredrik Nederberg
  • Patent number: 8633244
    Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: January 21, 2014
    Assignee: Cognis IP Management GmbH
    Inventor: Markus Dierker
  • Patent number: 8613868
    Abstract: The present invention relates to compounds represented by the following Formula I, In Formula I, R1 and R2 are each independently selected from hydrogen, and optionally substituted hydrocarbyl, provided that at least one of R1 and R2 is selected from optionally substituted hydrocarbyl (e.g., tertiary butyl); n is 0, 1 or 2, and each R3 is independently selected from optionally substituted hydrocarbyl; L1 is a divalent linking group, such as a bond or —C(O)O—; each L2 independently represents a flexible segment, such as divalent linear or branched C1-C25 alkyl; each L3 independently represents a rigid segment including, for example, optionally substituted phenylen-1,4-diyl groups; t is from 1 to 4; m and p are each independently from 0 to 4 for each t, provided that the sum of m and p is at least 1 for each t; and E can be, for example, C5-C18 aryl.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: December 24, 2013
    Assignee: Transitions Optical, Inc
    Inventors: Xiao-Man Dai, Ruisong Xu, Meng He, Anil Kumar, Rachael L. Yoest, Chenguang Li
  • Publication number: 20130310595
    Abstract: The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2?): wherein R is a fluorine atom or a methoxy group, and R400 is a hydrogen atom or a C1-C4 alkyl group, or a salt thereof, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
    Type: Application
    Filed: November 21, 2012
    Publication date: November 21, 2013
    Applicant: JAPAN TOBACCO INC.
    Inventor: Japan Tobacco Inc.
  • Patent number: 8580480
    Abstract: A radiation-sensitive resin composition includes (A) a fluorine-containing compound that includes a group shown by the following formula (1), and (B) a photoacid generator. wherein RC represents a (p+1)-valent aromatic ring group, Q represents a linking group obtained by removing one hydrogen atom from a monovalent hydrophilic group, RE represents a hydrogen atom or a hydrocarbon group having 1 to 10 carbon atoms, p is an integer from 1 to 5, provided that a plurality of Q and a plurality of RE may respectively be either the same or different when p is an integer from 2 to 5, and “*” indicates a bonding hand.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: November 12, 2013
    Assignee: JSR Corporation
    Inventors: Yusuke Asano, Mitsuo Sato
  • Publication number: 20130296323
    Abstract: This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.
    Type: Application
    Filed: February 27, 2013
    Publication date: November 7, 2013
    Applicant: COYOTE PHARMACEUTICALS, INC.
    Inventors: Hiroaki Serizawa, Ankush B. Argade, Akash Datwani, Natalie Spencer, Yonghua Pan, Florian Ermini
  • Publication number: 20130225822
    Abstract: The present invention relates to a chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof. The chiral spiro-pyridylamidophosphine compound is a compound having a structure of Formula (I), a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly characterized by having a chiral spiro-dihydro-indene skeleton in its structure. The chiral spiro-pyridylamidophosphine compound may be synthesized with optical active 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene or substituted 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene having a spiro-skeleton as chiral starting material. The chiral spiro-pyridylamidophosphine compound may be used as a chiral ligand in asymmetric hydrogenation of a carbonyl compound catalyzed by iridium, in which the reaction activity is very high, the amount of the catalyst may be 0.0001 mol %, and the enantioselectivity of the reaction is up to 99.9% ee.
    Type: Application
    Filed: November 18, 2011
    Publication date: August 29, 2013
    Inventors: Qilin Zhou, Jianhua Xie, Xiaoyan Liu, Jianbo Xie, Lixin Wang
  • Patent number: 8513454
    Abstract: The composition of a (phosphonyl) aromatic compound represented by is provided. In this composition, R1(a) and R1(b) are each independently H, CnH2n+1, phenyl or benzyl; R2(a) and R2(b) are each independently H, CnH2n+1, phenyl or benzyl with the proviso that no more than one R2(a) and no more than one R2(b) can be phenyl or benzyl; R3(a) and R3(b) are each independently CnH2n+1, phenyl or benzyl; and, n is an integer of 1-10; and p is an integer of 1-10. The disclosed composition can find utility in improving flame retardancy of polyesters, aramids and nylons.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: August 20, 2013
    Assignee: E I du Pont de Nemours and Company
    Inventors: Neville Everton Drysdale, Fredrik Nederberg
  • Publication number: 20130150612
    Abstract: The composition of a (phosphonyl) aromatic compound represented by is provided. In this composition, R1(a) and R1(b) are each independently H, CnH2n+1, phenyl or benzyl; R2(a) and R2(b) are each independently H, CnH2n+1, phenyl or benzyl with the proviso that no more than one R2(a) and no more than one R2(b) can be phenyl or benzyl; R3(a) and R3(b) are each independently CnH2n+1, phenyl or benzyl; and, n is an integer of 1-10; and p is an integer of 1-10. The disclosed composition can find utility in improving flame retardancy of polyesters, aramids and nylons.
    Type: Application
    Filed: December 8, 2011
    Publication date: June 13, 2013
    Applicant: E.I. DUPONT DE NEMOURS AND COMPANY
    Inventors: Neville Everton Drysdale, Fredrik Nederberg
  • Publication number: 20130143964
    Abstract: Disclosed are a sympathetic inhibitor allowing more effective inhibition of activity of a sympathetic nerve, as well as a cosmetic composition, a food, and a sundry article containing the same. Ethyl 4-methoxybenzoate is efficacious for quieting down the activity of the sympathetic nerve. The sympathetic inhibitor, the cosmetic composition, the food and the sundry article containing the same enable more effective inhibition of the activity of the sympathetic nerve.
    Type: Application
    Filed: May 26, 2011
    Publication date: June 6, 2013
    Inventors: Keiko Mori, Shinichiro Haze, Yoko Gozu, Atsushi Joichi
  • Patent number: 8454857
    Abstract: A polymerizable liquid crystal compound shown by the following formula, a polymerizable liquid crystal composition that includes the polymerizable liquid crystal compound and a chiral compound polymerizable with the polymerizable liquid crystal compound, a liquid crystalline polymer obtained by polymerizing the polymerizable liquid crystal compound or the polymerizable liquid crystal composition, and an optically anisotropic article that includes the liquid crystalline polymer, are disclosed.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: June 4, 2013
    Assignee: Zeon Corporation
    Inventors: Kei Sakamoto, Yasushi Nakano
  • Publication number: 20130115653
    Abstract: A method for utilizing woody biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from woody biomass for producing derivative products while minimizing waste products.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 9, 2013
    Applicant: Thesis Chemistry, LLC
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Publication number: 20130115654
    Abstract: A method for utilizing agricultural biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from agricultural biomass for producing derivative products while minimizing waste products.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 9, 2013
    Applicant: Thesis Chemistry, LLC
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Publication number: 20130053566
    Abstract: Cationic palladium catalysts comprising diamino carbene ligands, wherein the catalysts are of the formula [Pd(X)q(LBX)t(DC)]r+[Ym-]p or [Pd(X)q(LB)n(LBX)t(DC)]2a+[V?]u[Z2?]y, wherein DC is a diamino carbene ligand, X is an anionic ligand, LBX is a combined anionic and neutral ligand, and Y, V, and Z are non-coordinating anions. The compounds are useful in catalytic reactions, including cross-coupling reactions and hydroamination reactions. In particular, the catalysts are used in the following reactions: Suzuki-Miyaura coupling, Kumada coupling, Negishi coupling, Sonogashira coupling, Hartwig-Buchwald amination, and Heck-Mizoroki coupling.
    Type: Application
    Filed: April 14, 2011
    Publication date: February 28, 2013
    Inventors: Kamaluddin Abdur-Rashid, Dino Amoroso, Chi-Wing Tsang, Wenli Jia
  • Publication number: 20130040926
    Abstract: There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.
    Type: Application
    Filed: July 11, 2012
    Publication date: February 14, 2013
    Inventors: Stephen CONNOLLY, Mark Richard EBDEN, Iain Alastair Stewart WALTERS, Thomas LANGER, Alan Robert STEVEN, Craig Robert STEWART, Paula Margaret TOMLIN, Andrew John WILLIAMS
  • Publication number: 20130035467
    Abstract: A process for preparing a hybrid polyester-polyether polyol comprises contacting a carboxyl group-containing component and an epoxide, optionally in the presence of one or more of a double metal cyanide catalyst, a superacid catalyst, a metal salt of a superacid catalyst and/or a tertiary amine catalyst, under conditions such that a hybrid polyester-polyether polyol is formed. The hybrid polyester-polyether polyol offers the advantages of both ester and ether functionalities when used in a polyurethane formulation, thus enhancing physical properties. The process results in products having narrow polydispersity, a low acid number and unsaturation, and reduced byproduct formation, particularly when the double metal cyanide catalyst is employed.
    Type: Application
    Filed: April 21, 2011
    Publication date: February 7, 2013
    Inventors: Pavel L. Shutov, Jorge Jimenez, Hanno R. Van der Wal, Francois M. Casati
  • Patent number: 8318969
    Abstract: This invention provides alignment materials for liquid crystal display device of vertical alignment mode and methods for the preparation of the same, and more particularly, it provides diaminobenzene derivatives represented by the following formula 1: wherein n is an integer of 1 to 5 and R is an alkyl or alkoxy group of 3 to 5 carbon atoms, which align liquid crystal in uniform and vertical way, have not only excellent mechanical properties such as heat resistance and surface strength but also high pretilt angles of liquid crystal and in particular, can make response rate of liquid crystal fast, methods for the preparation of the same and liquid crystal alignment films using the same.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: November 27, 2012
    Assignee: Dongjin Semichem Co., Ltd.
    Inventors: Jin wook Choi, Eung jae Park, Jae cheol Park, Yong bae Kim
  • Publication number: 20120289695
    Abstract: Methods of producing organic materials, and in particular methods of producing petroleum materials and organic compounds such as aromatic acids, phenols, and aliphatic poly-carboxylic acids using an oxidative hydrothermal dissolution (OHD) process are disclosed.
    Type: Application
    Filed: June 4, 2012
    Publication date: November 15, 2012
    Applicant: SOUTHERN ILLINOIS UNIVERSITY CARBONDALE
    Inventors: Kenneth B. Anderson, John C. Crelling, William W. Huggett, Derek M. Perry
  • Patent number: 8293134
    Abstract: An optically anisotropic material having a good durability against light is provided. Further, an optical element having a good durability against light and an optical information writing/reading device employing such an element are provided. The optically anisotropic material is obtainable by polymerizing a polymerizable liquid crystal composition containing at least 5 mol % of at least one type of polymerizable compound represented by a general formula CH2?CR1—COO—K-Cy-Cy-L-OCO—CR2?CH2. A phase difference plate 4 produced by employing the optically anisotropic material has a good durability against light, and accordingly, the phase difference plate 4 can realize an optical heat device suitable for large capacity writing/reading by employing a blue laser as a light source 1.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: October 23, 2012
    Assignee: Asahi Glass Company, Limited
    Inventors: Satoshi Okada, Hiroshi Kumai, Makota Hasegawa
  • Patent number: 8288436
    Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: October 16, 2012
    Assignee: Cognis IP Management GmbH
    Inventor: Markus Dierker
  • Publication number: 20120258249
    Abstract: Certain ether-esters compounds and certain ether ester coalescents are provided. Also provided are an aqueous coating composition including an aqueous polymeric dispersion and from 0.1% to 40% by weight, based on the weight of the aqueous polymeric dispersion solids, of the glycol ether-ester coalescents and a method for forming a coating from the aqueous coating composition.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 11, 2012
    Inventors: Linda A. ADAMSON, Michael C. BECKER, Felipe A. DONATE, David M. FASANO, Sarah E. ITTNER, Rebecca J. WACHOWICZ, Thomas R. TEPE
  • Patent number: 8262932
    Abstract: A polymerizable liquid crystal compound represented by formula (I) is disclosed. R0 and R1 represent a hydrogen atom, or a C1-4 alkyl group, provided that at least one of R0 and R1 represent a C1-4 alkyl group; A0, A1, B0 and B1 represent a single bond, or a divalent linking group having a cyclic structure; X0, X1, Y0 and Y1 represent a single bond, —O—, —S—, —OCO—, —COO—, —OCOO—, —NR2CO—, —CONR2—, —OCONR2—, —NR2COO—, —NR2CONR2—, —C?N— or —N?C—; Q0 and Q1 a single bond or a divalent aliphatic group; Z0 and Z1 represent a hydrogen atom, cyano, halogen atom or polymerizable group; and n and m each independently represent an integer of from 0 to 2.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: September 11, 2012
    Assignee: FUJIFILM Corporation
    Inventors: Shunya Katoh, Mitsuyoshi Ichihashi
  • Publication number: 20120223270
    Abstract: A method comprises forming a reaction mixture comprising a terephthalate polyester, a glycol comprising 2 to 5 carbons, and an amidine organocatalyst; and heating the reaction mixture at a temperature of about 120° C. or more to depolymerize the terephthalate polyester, thereby forming a terephthalate reaction product comprising a monomeric dihydroxy terephthalate diester; wherein the terephthalate reaction product contains terephthalate oligomers in an amount less than the amount of terephthalate oligomers that would result from i) substituting the amidine organocatalyst with an equimolar amount of a guanidine catalyst and ii) depolymerizing the terephthalate polyester under otherwise identical reaction conditions.
    Type: Application
    Filed: March 4, 2011
    Publication date: September 6, 2012
    Applicants: KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY, INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Abdullah M. Alabdulrahman, Hamid A. Almegren, Fares D. Alsewailem, Phillip Joe Brock, Daniel Joseph Coady, Kazuki Fukushima, James Lupton Hedrick, Hans Werner Horn, Julia Elizabeth Rice
  • Publication number: 20120205578
    Abstract: A polishing composition, comprising a compound having structure I or salts thereof: wherein R1 is selected from the group consisting of —O?Mx+ wherein x is selected from the group consisting of 1, 2, and 3, —O—R3 wherein R3 is selected from the group consisting of alkyl, allyl, and phenyl, —N(R3R4) wherein R4 is selected from the group consisting of —H, alkyl, allyl, and phenyl, and —S—R3, and wherein R2 is selected from the group consisting of —CH2—CO2—CH3, —CO—NH—R5, —CH2—CH(OH)—CH2—OH, —CH2—CH(OH)—CH2—R3, and —CH2-substituted phenyl, wherein R5 is selected from the group consisting of alkyl and substituted phenyl.
    Type: Application
    Filed: November 15, 2011
    Publication date: August 16, 2012
    Inventor: John L. Lombardi
  • Publication number: 20120178704
    Abstract: Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.
    Type: Application
    Filed: December 7, 2007
    Publication date: July 12, 2012
    Inventors: Agnes M. Rimando, Nanjoo Suh, Cassia Mizuno, Bandaru s. Reddy, Sada L. Reddy
  • Patent number: 8217075
    Abstract: 2-amino-2-phenyl-alkanol ester derivatives of general formula (I) in which: R1 is H, straight or branched 1 to 4C alkyl, straight or branched 2 to 4C alkyl substituted by OH, alkoxy, alkylthio, acyloxy, NH2, alkylamino, dialkylamino, alkylcarbamoyloxy, alkoxycarbonylamino, ureido or alkylureido, R2 is a —CO—R radical in which R is H, alkyl, aryl, heterocyclyl, benzyl or heterocyclylmethyl, or R2 is a —CO—Y—R4 radical for which Y is —O—, —S—, —NH—, -Nalk- for which alk is straight or branched (1 to 4C) alkyl, and R4 is alkyl, aryl, aralkyl or heterocyclylalkyl, capable of being substituted by one or more halogen atoms or OH radicals, straight or branched (1 to 4C) alkyl, alkoxy, alkylthio, acylaminoalkylthio, alkoxycarbonyl or acylamino (1 to 4C) straight or branched, or oxo, or capable of being substituted by R5COO— in which R5 is alkyl optionally substituted by benzyloxycarbonylamino, acylamino or by an amino acid residue, or represents an heterocyclyl radical, or R2 is alkyl (2 to 4C) substituted by OH, alk
    Type: Grant
    Filed: January 27, 2009
    Date of Patent: July 10, 2012
    Assignee: Oroxcell
    Inventors: Jean Pachot, Christophe Dini, Alexis Denis
  • Publication number: 20120172337
    Abstract: The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient.
    Type: Application
    Filed: March 8, 2012
    Publication date: July 5, 2012
    Applicant: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Henri Dasseux, Carmen Daniela Oniciu
  • Publication number: 20120148690
    Abstract: A novel skin barrier function recovery acceleration method and accelerator are provided. The present invention provides a skin barrier function recovery accelerator that comprises a TRPA1 agonist capable of activating TRPA1 in epidermal cells.
    Type: Application
    Filed: December 10, 2010
    Publication date: June 14, 2012
    Inventors: Mitsuhiro Denda, Moe Tsutsumi, Sumiko Denda
  • Patent number: 8188306
    Abstract: Novel compounds useful for inhibiting the 90kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: May 29, 2012
    Assignee: University of Kansas
    Inventors: Brian S. J. Blagg, Gang Shen
  • Patent number: 8143436
    Abstract: Process for preparing a compound of the formula by contacting, in an organic solvent in the presence of an aqueous solution of a base, hydroxy benzoic acid with a compound of the formula RnX, wherein R is an alkyl group having 1 to 6 C-atoms and X is an acid rest group having a valence n, wherein the organic solvent is an alkyl substituted aromatic hydrocarbon and the reaction is carried out at a pH of 8-10.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: March 27, 2012
    Assignee: Saudi Basic Industries Corporation
    Inventor: Jaiprakash Brijlal Sainani
  • Publication number: 20120040984
    Abstract: The invention relates to compounds of the formula (I) either (i) in the state of a base or an acid addition salt, or (ii) in the state of an acid or a base addition salt, as well as to a method for preparing same and to the therapeutic applications thereof.
    Type: Application
    Filed: January 27, 2010
    Publication date: February 16, 2012
    Applicant: SANOFI
    Inventors: Eykmar Fett, Patrick Mougenot, Claudie Namane, Eric Nicolai, Christophe Philippo
  • Patent number: 8101095
    Abstract: The racemic and chiral compounds expressed by common formula 1 and formula 2: wherein the lateral substituents X1, X2, X3, X4, X5, X6, X7 and X8 in the benzene rings represent independently hydrogen and fluorine atoms, bridge group Z represent independently the single bond or COO, CH2CH2, CH2O and OCH2 group, substituent Y represents CH3, or CH2F, CHF2, CF3, C2H5 group, symbols n, m, r and t are independently integers of 1 to 8; symbols p and s signify independently number of 0 to 1 and its orthoconic antiferroelectric long helical pitch mixtures prepared by the methods 1) to the racemic components selected from compounds 1 are added chiral components selected from the compound of formula 1 and/or chiral components selected from the compounds of formula 2 and/or another optically active compounds with high helical twisting power, 2) to chiral compound 1 which helical pitches increases with the temperature increase is added chiral compound 1 which helical pitch decreases with temperature increase.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: January 24, 2012
    Assignee: Wojskowa Akademia Techniczna IM. Jaroslawa Dabrowskiego
    Inventors: Roman Slawomir Dabrowski, Krzysztof Ludwik Czuprynski, Przemyslaw Kula, Magdalena Zurowska, Wojciech Rejmer, Wiktor Piecek, Zbigniew Raszewski
  • Publication number: 20110312864
    Abstract: The present invention relates to alcohols and in particular to C4 to C15 alcohols that are used in the production of esters.
    Type: Application
    Filed: December 3, 2009
    Publication date: December 22, 2011
    Inventors: Allen D. Godwin, Philippe L. Buess, Raphael F. Caers, Arie Van Vliet, Eddy T.A. Van Driessche, Alfons Cuyckens
  • Publication number: 20110280940
    Abstract: The invention relates to the medical field, more precisely in the field of anti-cancer treatment and treatment of Alzheimer's disease, Parkinson's disease or Pick's disease or for ameliorating symptoms of Down syndrome, providing newly synthesised multi-vanilloyl derivative compounds and their use in the treatment of said disorders.
    Type: Application
    Filed: October 13, 2009
    Publication date: November 17, 2011
    Inventors: Robert Kiss, Jacques Dubois, Jean Neve, Delphine Lamoral-Theys, Francois Dufrasne, Laurent Pottier
  • Patent number: 8043789
    Abstract: A photosensitive compound whose size is smaller than conventional polymer for photoresist, and which has well-defined (uniform) structure, and a photoresist composition including the same are disclosed. The photosensitive compound represented by the following formula. Also, the present invention provides a photoresist composition comprising 1 to 85 wt % (weight %) of the photosensitive compound; 0.05 to 15 weight parts of a photo-acid generator with respect to 100 weight parts of the photosensitive compound; and 10 to 5000 weight parts of an organic solvent. In the formula, n is 0 or 1, x is 1, 2, 3, 4 or 5, y is 2, 3, 4, 5 or 6, z is 0, 1, 2, 3 or 4, R, R? and R? are independently hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms, and R?? is a hydrogen atom or hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: October 25, 2011
    Assignee: Dongjin Semichem Co., Ltd.
    Inventors: Jae-Woo Lee, Min-Ja Yoo, Jun-Gyeong Lee, Young-Bae Lim, Jae-Hyun Kim
  • Patent number: 8034967
    Abstract: A method of producing a purified ester-substituted phenol stream is provided. The method includes a first step of obtaining from a melt transesterification reaction a byproduct stream containing a residual ester-substituted diaryl carbonate, an ester-substituted phenol, a residual melt transesterification catalyst, and a catalyst degradation product. A second step includes treating the reaction byproduct stream to separate ester-substituted phenol and catalyst degradation product from residual ester-substituted diaryl carbonate and residual melt transesterification catalyst to create a light recycle stream containing ester-substituted phenol and catalyst degradation product and a heavy recycle stream containing residual ester-substituted diaryl carbonate and residual melt transesterification catalyst. A third step includes treating the light recycle stream to reduce catalyst degradation product concentration thereby producing a purified ester-substituted phenol stream.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: October 11, 2011
    Assignee: Sabic Innnovative Plastics IP B.V.
    Inventors: Hatem Belfadhel, Stephan Bouwens, Martin Herke Oyevaar
  • Publication number: 20110230532
    Abstract: A compound having the structure wherein Y is selected from the group consisting of —C(O)OR2, —C(O)NHR8, —C(CH2)1-2OR3, OH, and or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
    Type: Application
    Filed: July 27, 2009
    Publication date: September 22, 2011
    Inventors: Amjad Ali, Robert K. Baker, Kathleen M. Rupprecht, Michael Man-Chu Lo, Brent Whitehead
  • Publication number: 20110201716
    Abstract: Polyester polyol comprising the esterification product of a) from 10 to 70 mol % of a dicarboxylic acid composition comprising a1) from 50 to 100 mol % of a material based on terephthalic acid, selected from among terephthalic acid, dimethyl terephthalate, polyalkylene terephthalate and mixtures thereof, a2) from 0 to 50 mol % of phthalic acid, phthalic anhydride or isophthalic acid, a3) from 0 to 50 mol % of one or more dicarboxylic acids, b) from 2 to 30 mol % of one or more fatty acids and/or fatty acid derivatives and/or benzoic acid, c) from 10 to 70 mol % of one or more aliphatic or cycloaliphatic diols having from 2 to 18 carbon atoms or alkoxylates thereof, d) from 2 to 50 mol % of a higher-functional polyol selected from the group consisting of glycerol, alkoxylated glycerol, trimethylolpropane, alkoxylated trimethylolpropane, pentaerythritol and alkoxylated pentaerythritol, wherein at least 200 mmol, preferably at least 500 mmol and particularly preferably at least 800 mmol, of polyols d) havin
    Type: Application
    Filed: October 13, 2009
    Publication date: August 18, 2011
    Applicant: BASF SE
    Inventors: Lionel Gehinger, Gunnar Kampf, Gerlinde Tischer