Tannins And Reaction Products Thereof Patents (Class 560/68)
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Patent number: 9187346Abstract: A method for removing uranium from an uranium-containing aqueous solution having a salinity of at least 0.5 ppt, comprise the step of passing the solution through a bed of anion exchange resin impregnated with polyphenol.Type: GrantFiled: January 27, 2014Date of Patent: November 17, 2015Assignee: ROHM AND HAAS COMPANYInventors: Areski Rezkallah, Jean-Francois Ferraro, Paul-Michael Pellny
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Patent number: 8592426Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.Type: GrantFiled: January 17, 2012Date of Patent: November 26, 2013Assignee: Hoffmann—La Roche Inc.Inventors: Johannes Aebi, Alfred Binggeli, Cornelia Hertel, Anish Ashok Konkar, Holger Kuehne, Bernd Kuhn, Hans P. Maerki, Haiyan Wang
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Publication number: 20120238638Abstract: This invention pertains to a method of modifying biocides obtained from biological sources, namely polyphenols. The modified biocide may have protective groups to reduce or prevent the oxidation of these phenols. The protective groups may also control the rate of hydrolyzation with regards to biocide efficacy. This invention also includes a method wherein the modified biocide may be incorporated and stabilized into a substrate like plastic.Type: ApplicationFiled: March 19, 2012Publication date: September 20, 2012Inventor: Jorma Antero Virtanen
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Publication number: 20100240600Abstract: Provided is an anti-norovirus agent that has high norovirus-inactivating activity and is safe for the human body, and an anti-norovirus composition that contains the anti-norovirus agent and is useful for disinfection and infection control against the norovirus. The anti-norovirus agent includes, as an active ingredient, an extract from a plant of the genus Diospyros containing tannin (hereinafter referred to as a “persimmon extract”), preferably a persimmon extract produced by heating squeezed juice or an extract from the fruit of a plant of the genus Diospyros or treating the squeezed juice or the extract with an alcohol. The anti-norovirus composition contains the anti-norovirus agent and at least one selected from the group consisting of alcohols, surfactants, antimicrobial agents, humectants, and cosmetic fats and oils, and preferably further containing an organic acid, such as citric acid, and/or a salt thereof or vitamin C.Type: ApplicationFiled: June 11, 2008Publication date: September 23, 2010Applicants: HIROSHIMA UNIVERSITY, ALTAN CO., LTD.Inventors: Tadashi Shimamoto, Toru Tsuji, Yoshiaki Nakai
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Publication number: 20080255282Abstract: This invention teaches a charge control agent and a toner containing such a charge control agent. It solves the problem in current toner processing technique of inadequate electrification, unequal quantity of electricity, spreading and bottom ash. The charge control agent comprising metal complex of tannin acid in which metal atoms have 2 to 4 valences and tannin acid as coordination sub structure. The toners mentioned above at least contains resin, dyestuff and charge control agent of the invention. The powered carbon specializes in excellence in electrification, environment influence retardant. It can obtain stable and high definition image without spreading and bottom ash troubling.Type: ApplicationFiled: January 10, 2008Publication date: October 16, 2008Applicant: HUBEI DINGLONG CHEMICAL CO., LTD.Inventors: Delian YI, Lin WU, Shunquan ZHU
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Patent number: 6939856Abstract: The invention pertains to a method for preparing dexchlorpheniramine (“dexchlor”) tannate by reacting dexchlorpheniramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The dexchlorpheniramine free base may be obtained by reacting a commercially available dexchlorpheniramine salt such as dexchlorpheniramine maleate with a base such as aqueous sodium hydroxide. The resultant dexchlor tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.Type: GrantFiled: August 14, 2003Date of Patent: September 6, 2005Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Raja G. Achari, Angelo R. Mellozzi, Vilas M. Chopdekar
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Patent number: 6881744Abstract: The invention pertains to carbinoxamine tannate and to a method for preparing carbinoxamine tannate by reacting carbinoxamine free base at a temperature of about 50 to about 150° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: GrantFiled: December 20, 2002Date of Patent: April 19, 2005Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, Dina Donatiello, Timothy N. Truong, Vilas M. Chopdekar
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Patent number: 6833360Abstract: The invention pertains to a method for preparing pseudoephedrine tannate by reacting pseudoephedrine free base at a temperature of about 70 to about 110° C. with tannic acid neat or as an aqueous slurry containing about 5 to about 30 wt. % water.Type: GrantFiled: December 20, 2002Date of Patent: December 21, 2004Assignee: Jame Fine Chemicals, Inc.Inventors: Sham N. Redkar, James R. Schleck, Vilas M. Chopdekar
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Patent number: 6790980Abstract: The present invention is directed to methods and compositions for treating upper respiratory indications, such as the treatment, management or mitigation of cough, cold, cold-like symtoms, symtoms related to upper respiratory infections, influenza symptoms and allergic rhinitis, perennial rhinitis, nasal and Eustachian tube congestion in an animal by administration of tannate compositions comprising single agent formulations or combinations of at least one or more agents into a single administrative dose.Type: GrantFiled: October 2, 2002Date of Patent: September 14, 2004Assignee: First Horizon Pharmaceutical CorporationInventor: Balaji Venkataraman
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Patent number: 6689817Abstract: The invention pertains to a process for preparing guaifenesin tannate. The process involves the steps of mixing guaifenesin with tannic acid in the presence of water, continuing to mix the reaction mixture for about 5 minutes to about 4 hours and thereafter removing at least about 80 wt.% of the water by freeze-drying the reaction mixture.Type: GrantFiled: December 14, 2001Date of Patent: February 10, 2004Assignee: Jame Fine Chemicals, Inc.Inventors: Cheng Guo, Vilas M. Chopdekar
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Patent number: 6677381Abstract: The invention pertains to a novel composition comprising guaifenesin tannate and to a method for preparing guaifenesin tannate by reacting guaifenesin with tannic acid at a temperature above the melting point of guaifenesin. The guaifenesin tannate has extended release properties and is useful in pharmaceutical compositions as an expectorant in warm-blooded animals or as a muscle relaxant in non-human animals.Type: GrantFiled: December 14, 2001Date of Patent: January 13, 2004Assignee: Jame Fine Chemicals, Inc.Inventors: James R. Schleck, Vilas M. Chopdekar
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Patent number: 6670370Abstract: The invention pertains to a composition comprising dextromethorphan tannate and to a method for preparing dextromethorphan tannate by reacting dextromethorphan at a temperature of about 80 to about 180° C. with tannic acid either neat or as an aqueous slurry containing about 5 to about 30 wt. % water. The dextromethorphan tannate has extended release properties and is useful in pharmaceutical compositions as an antitussive for human beings.Type: GrantFiled: October 28, 2002Date of Patent: December 30, 2003Assignee: Jame Fine Chemicals, Inc.Inventors: Vilas M. Chopdekar, James R. Schleck, Hemant S. Desai
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Publication number: 20030236202Abstract: The invention relates to the use of phenolic compounds and derivatives thereof for protection against neurodegenerative diseases, to compositions comprising these compounds, and to some novel phenolic compounds.Type: ApplicationFiled: April 3, 2003Publication date: December 25, 2003Inventors: Arjan Geelings, Eduardo Lopez-Huertas Leon, Juan Carlos Morales Sanchez, Julio Boza Puerta, Jesus Jimenez Lopez
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Patent number: 6509492Abstract: The present invention is directed to methods and compositions for treating upper respiratory indications, such as the treatment, management or mitigation of cough, cold, cold-like symptoms, symptoms related to upper respiratory infections, influenza symptoms and allergic rhinitis, perennial rhinnitis, nasal and Eustachian tube congestion in an animal by administration of tannate compositions comprising combinations of at least one or more agents into a single administrative dose.Type: GrantFiled: September 14, 2001Date of Patent: January 21, 2003Assignee: First Horizon Pharmaceutical CorporationInventor: Balaji Venkataraman
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Patent number: 6462094Abstract: Compositions consisting essentially of phenylephrine tannate and guaifenesin which are effective when administered orally for the symptomatic relief of cough associated with respiratory tract conditions such as the common cold, bronchial asthma, acute and chronic bronchitis are disclosed.Type: GrantFiled: August 22, 2001Date of Patent: October 8, 2002Assignee: Medpointe Healthcare Inc.Inventors: Phuong Grace Dang, Alexander D. D'Addio
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Patent number: 6455727Abstract: The invention pertains to a process for preparing carbetapentane tannate. The process involves the steps of heating carbetapentane to a temperature of about 80 to about 120° C. and slowly adding tannic acid to the carbetapentane while agitating the reaction mixture. Preferably, no water or any other solvent or diluent is utilized in the process.Type: GrantFiled: December 14, 2001Date of Patent: September 24, 2002Assignee: Jame Fine Chemicals, Inc.Inventors: Vilas M. Chopdekar, James R. Schleck, Hemant S. Desai
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Patent number: 6410777Abstract: The present invention provides a salicylic acid ester derivative having an impurity content lower than a specific level and expressed by the following formula (1) (in the formula, R1 is methyl group or ethyl group, R2, which may be substituted optionally, is an alkyl group having a carbon number of from 1 to 30, alkoxy group having a carbon number of from 1 to 30, aryl group having a carbon number of from 6 to 30, aryloxy group having a carbon number of from 6 to 30, aralkyl group having a carbon number of from 6 to 30 or aralkyloxy group having a carbon number of from 6 to 30). The salicylic acid ester derivative is effective as a terminal blocking agent or a polymerization. promoting agent for a polycarbonate, and gives a polycarbonate having good color tone and suitable for optical material use.Type: GrantFiled: October 4, 1999Date of Patent: June 25, 2002Assignee: Teijin LimitedInventors: Hiroaki Kaneko, Wataru Funakoshi, Katsushi Sasaki
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Patent number: 6337411Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of conditions whose course involves an increased activity of matrix-degrading enzymes, in particular stromelysin.Type: GrantFiled: December 15, 2000Date of Patent: January 8, 2002Assignee: Aventis Pharma Deutschland GmbHInventors: Cordula Hopmann, Martin Albert Knauf, Klaus-Ulrich Weithmann, Joachim Wink
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Publication number: 20010011104Abstract: Tannate compositions consisting essentially of carbetapentane tannate, phenylephrine tannate and chlorpheniramine tannate which are effective when administered orally for the symptomatic relief of coryza associated with the common cold, sinusitis, allergic rhinitis and upper respiratory tract conditions are disclosed.Type: ApplicationFiled: December 11, 1998Publication date: August 2, 2001Inventor: STEVEN A. GORDZIEL
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Patent number: 6264840Abstract: The process of the present invention comprises the steps of (a) a step of dissolving a condensed tannin powder in an aqueous alkaline solution, (b) a step of admixing an aqueous aldehyde solution with the aqueous solution obtained in the step (a), (c) a step of adding the aqueous solution obtained by the above step (b) to a hydrophobic solvent containing a polyether type nonionic surfactant under heating and stirring to disperse the aqueous solution in the form of droplets in said hydrophobic solvent and (d) evaporating water components from the above-mentioned droplets to form a spherical and gelled insoluble tannins. Water content of the gel can be widely controlled as 5 to 90% as compared with the conventional adsorbent and the network structure and molecular space are changed depending on the size of the metal ion to be adsorbed so that a gelled insoluble tannin which can increase an adsorption capacity of metals can be obtained.Type: GrantFiled: August 27, 1999Date of Patent: July 24, 2001Assignee: Mitsubishi Nuclear Fuel Co., Ltd.Inventors: Yoshio Nakano, Yasuo Nakamura
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Patent number: 6063770Abstract: A pharmaceutical composition including tannic acid and tannin complexes from a plant of the Musaceas family (banana, plantain, etc.), and a method of treating cancer with tannic acid and tannin complexes.Type: GrantFiled: April 21, 1998Date of Patent: May 16, 2000Assignee: Atajje, Inc.Inventor: Juan Falcon
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Patent number: 5663415Abstract: A process for preparing pure antihistamine tannate compositions. The antihistamine in the form of its free base is contacted with tannic acid in the presence of water for a period of time of about 5 minutes to 4 hours and at a maximum temperature such that not more than about 5 wt. % of the antihistamine tannate will be decomposed. Water is removed from the antihistamine tannate by freeze-drying.Type: GrantFiled: June 28, 1996Date of Patent: September 2, 1997Assignee: Jame Fine Chemicals, Inc.Inventors: Vilas M. Chopdekar, James R. Schleck, Vernon A. Brown, Cheng Guo
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Patent number: 5522927Abstract: Compositions and methods relating to cementitious compositions are provided. The use of a blend of a rosin and a tannin to entrain air into cementitious compositions is provided. A blend of a rosin and a tannin in a weight ratio of about 1:1.22 to about 1:1.86 are added to a wet cementitious composition at levels of less than 1% by weight based on the weight of the cement and air is mixed into the cement. The resulting cement will contain, e.g. 5% to 10% by volume air which improves the resistance of the set cement to freeze damage. Also provided is a method of entraining air into a cementitious composition which employs such a blend.Type: GrantFiled: May 24, 1995Date of Patent: June 4, 1996Assignee: Henkel CorporationInventor: Timothy Hegge
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Patent number: 5431729Abstract: Compositions and methods relating to cementitious compositions are provided. The use of a blend of a rosin and a tannin to entrain air into cementitious compositions is provided. A blend of a rosin and a tannin in a weight ratio of 10:1 to 1:10 are added to a wet cementitious composition at levels of less than 1% by weight based on the weight of the cement and air is mixed into the cement. The resulting cement will contain, e.g. 5% to 10% by volume air which improves the resistance of the set cement to freeze damage. Also provided is a method of entraining air into a cementitious composition which employs such a blend.Type: GrantFiled: April 12, 1994Date of Patent: July 11, 1995Assignee: Henkel CorporationInventor: Timothy Hegge
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Patent number: 5376615Abstract: A color-developing composition comprises a multi-valent-metal-modified salicylic acid resin (Resin A) and a polycondensation resin (resin B) at a weight ratio of 90-30 to 10-70. Resin A is composed of 5-35 mole % of a structural unit (I) and 65-95 mole % of at least one structural unit (II) or 65-95 mole % of a coupled structural unit of at least one unit (II) and at least one unit (III) and has a weight-average molecular weight of 350-5,000. Resin B is composed of the unit (II) and/or the unit (III) and has a weight-average molecular weight of 350-5,000. ##STR1## wherein Z represents M/m, M being a metal ion of m valence and m being an integer; R.sub.1 and R.sub.2 represent H or a C.sub.1-12 alkyl, aralkyl, aryl or cycloalkyl group; R.sub.3 and R.sub.6 represent H or a C.sub.1-4 alkyl group; and R.sub.4 and R.sub.5 represent H or CH.sub.3.Type: GrantFiled: July 20, 1992Date of Patent: December 27, 1994Assignee: Mitsui Toatsu Chemicals, IncorporatedInventors: Keizaburo Yamaguchi, Yoshimitsu Tanabe, Kiyoharu Hasegawa, Akihiro Yamaguchi
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Patent number: 5358713Abstract: A method for preventing infection caused by an antibiotic-resistant staphylococcus, which includes applying an effective antibacterial amount of tea or a tea polyphenol to an individual.Type: GrantFiled: July 22, 1993Date of Patent: October 25, 1994Assignees: Mitsui Norin Co., Ltd., Tadakatsu ShimamuraInventor: Tadakatsu Shimamura
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Patent number: 5330755Abstract: Desugared carob pod is treated with superheated steam to pasteurize and dry the carob.Type: GrantFiled: June 19, 1992Date of Patent: July 19, 1994Assignee: Nestec S.A.Inventor: Remi Thomas
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Patent number: 5300677Abstract: An insoluble hydrolysable tannin is prepared by dissolving a hydrolysable tannin powder in aqueous ammonia; mixing the resulting solution with an aldehyde aqueous solution to form a precipitate; heating the precipitate; mixing the heated precipitate with a mineral acid; and filtering the resulting mixture to leave a residue on a filter. The inventive insoluble tannin exhibits high adsorption properties for heavy metal elements and is insoluble in either water, acid, or alkali. Methods for treating waste liquids and recovering heavy metal elements therefrom using the inventive insoluble tannin are disclosed.Type: GrantFiled: January 22, 1993Date of Patent: April 5, 1994Assignee: Mitsubishi Nuclear Fuel Company Ltd.Inventors: Wataru Shirato, Yoshinobu Kamei
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Patent number: 5296629Abstract: An insoluble hydrolysable tannin is prepared by dissolving a hydrolysable tannin powder in aqueous ammonia; mixing the resulting solution with an aldehyde aqueous solution to form a precipitate; heating the precipitate; mixing the heated precipitate with a mineral acid; and filtering the resulting mixture to leave a residue on a filter. The inventive insoluble tannin exhibits high adsorption properties for heavy metal elements and is insoluble in either water, acid, or alkali. Methods for treating waste liquids and recovering heavy metal elements therefrom using the inventive insoluble tannin are disclosed.Type: GrantFiled: January 22, 1993Date of Patent: March 22, 1994Assignee: Mitsubishi Nuclear Fuel Company, Ltd.Inventors: Wataru Shirato, Yoshinobu Kamei
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Patent number: 5274169Abstract: An insoluble hydrolysable tannin is prepared by dissolving a hydrolysable tannin powder in aqueous ammonia; mixing the resulting solution with an aldehyde aqueous solution to form a precipitate; heating the precipitate; mixing the heated precipitate with a mineral acid; and filtering the resulting mixture to leave a residue on a filter. The inventive insoluble tannin exhibits high adsorption properties for heavy metal elements and is insoluble in either water, acid, or alkali. Methods for treating waste liquids and recovering heavy metal elements therefrom using the inventive insoluble tannin are disclosed.Type: GrantFiled: July 23, 1992Date of Patent: December 28, 1993Assignee: Mitsubishi Nuclear Fuel Company, Ltd.Inventors: Wataru Shirato, Yoshinobu Kamei
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Patent number: 5238680Abstract: Method for extracting tannins from bark and multi-stage apparatus suitable therefor. The method includes the steps of: contracting bark containing tannins with a first tannin enriched aqueous wash medium at elevated temperatures; separating the tannin-rich liquid extract by filtration including dewatering the resulting filter cake under pressure; washing the filter cake with a plurality of aqueous wash media at elevated temperatures; and separating the tannin enriched media after each washing stage by filtration including dewatering the filter cake under pressure; wherein each successive wash medium has a lower degree of tannin enrichment than the preceding wash medium.Type: GrantFiled: April 2, 1991Date of Patent: August 24, 1993Assignee: Chem Eng Contracts Pty LtdInventor: David L. Connolly
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Patent number: 5023366Abstract: Disclosed herein are salicylic acid copolymers having a weight average molecular weight of 500-10,000 and obtained (a) by condensing salicylic acid (i) with a benzyl alcohol (ii) and/or benzyl ether (iii) or a benzyl halide (iv) in the presence of an acid catalyst or (b) by reacting a co-condensation resin of (i) and (ii) and/or (iii) with (iv) or (c) by reacting a co-condensation resin of (i) and (ii) and/or (iii) or (iv) with a styrene derivative in the presence of an acid catalyst; multivalent metal salts of the salicylic acid copolymers; color-developing agents comprising the multivalent metal salts; and color-developing sheets suited for pressure-sensitive copying paper and comprising the color-developing agents. Their production processes are also disclosed.Type: GrantFiled: October 23, 1987Date of Patent: June 11, 1991Assignee: Mitsui Toatsu Chemicals, IncorporatedInventors: Keizaburo Yamaguchi, Yoshimitsu Tanabe, Makoto Asano, Akihiro Yamaguchi
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Patent number: 4981485Abstract: Disclosed is a hair-dyeing composition comprising one or more tannins and one or more compounds selected from water-soluble zinc, copper, tin, magnesium and aluminum salts. The composition may be in the form of either a one-solution-type or a two-solution-type. The composition may dye hair in any desired color, and the color fastness of the dyed hair is excellent.Type: GrantFiled: March 15, 1989Date of Patent: January 1, 1991Assignees: Sansho Seiyaku Co., Ltd., Teruaki HayashiInventor: Masahiro Motono
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Patent number: 4755618Abstract: A process for recovering active gallotannin for reuse comprising the extracting of dried schoene sludge (about 5% moisture) with a mixture of about 88 vol. % acetone--12 vol. % water to solubilize the gallotannins. The solvent is evaporated off, the residue is treated with water to solublize the gallotannins. After filtration, the clarified water solution is extracted with ethyl acetate. Evaporation of ethyl acetate leaves purified gallotannin which can be redissolved in water and spray dried to produce reusable powder. A preliminary step of separating yeast from the gallotannin protein complex involves treating with 60% acetone/40% H.sub.2 O at room temperature before making the solution about 88:12 acetone:water.Type: GrantFiled: June 2, 1987Date of Patent: July 5, 1988Assignee: Anheuser-Busch, IncorporatedInventors: Duane A. Bude, Ellen Y. Lin
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Patent number: 4710586Abstract: A novel ammonium salt of quebracho prepared by reacting quebracho with alkyl quaternary ammonium salts is an effective fluid loss control agent when used in oil base drilling fluids for use in drilling oil and gas wells, especially in water in oil emulsion drilling mud formulations, controlling filtrate loss of the oil-base mud under high temperature and high pressure conditions.Type: GrantFiled: October 17, 1984Date of Patent: December 1, 1987Assignee: Dresser Industries, Inc.Inventors: Arvind D. Patel, Carmelita S. Salandanan
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Patent number: 4544666Abstract: A chemotherapeutic composition for the control of plant diseases caused by mycoplasma-like organisms, rickettsia-like organisms, or seed-borne legume viruses. The composition is composed essentially of the tannate complex of picro ammonium formate combined with a minor amount of a surfactant sufficient to prevent formation of ammonium picrate. The preparation and use of the composition are disclosed. Also disclosed is a related chemotherapeutic composition for the control of plant diseases caused by plant pathogenic fungi and bacteria and composed essentially of a tannate complex of picro cupric ammonium formate in aqueous solution combined with a minor amount of a surfactant sufficient to prevent formation of ammonium picrate, along with its method of preparation and manner of use.Type: GrantFiled: April 22, 1983Date of Patent: October 1, 1985Assignee: Phyton/AG, Inc.Inventors: Mandayam J. Thirumalachar, Mandayam J. Narasimhan, Mandayam J. K. Thirumalachar
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Patent number: 4471134Abstract: A mixture of intermediate products including a carboxylic salt of 3,4,5-trimethoxybenzoic acid (TMB acid) and a dimethoxy benzoic acid derivative of such salt further containing an oxygen anion in the 3,4, or 5 position is prepared by initially reacting hydrolyzable tannin with a methylation agent in an alkaline medium under methylation conditions to form methylated tannin and thereafter hydrolyzing the methylated tanning by reaction thereof with a hydrolysis agent under alkaline hydrolysis conditions. The resulting reaction mixture is then methylated to form a reaction mixture containing methyl 3,4,5-trimethoxybenzoate and a salt of 3,4,5-trimethoxybenzoic acid. TMB acid can be formed in high yield by conversion of both the methyl ester thereof and the salt thereof. Such conversion can be effected by hydrolyzing the reaction mixture followed by acidification thereof.Type: GrantFiled: September 29, 1982Date of Patent: September 11, 1984Assignee: Mallinckrodt, Inc.Inventor: Muthunadar P. Periasamy
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Patent number: 4408065Abstract: An adsorptive separation process for separating methylparaben from a feed mixture comprising methylparaben and wintergreen oil, which process comprises contacting the feed mixture with an adsorbent comprising a type X or type Y zeolite, selectively adsorbing substantially all of the methylparaben to the substantial exclusion of the wintergreen oil and thereafter recovering high-purity methylparaben. A desorption step may be used to desorb the adsorbed methylparaben. The process is carried out preferably in the liquid phase.Type: GrantFiled: March 23, 1981Date of Patent: October 4, 1983Assignee: UOP Inc.Inventors: Armand J. deRosset, James W. Priegnitz, Arthur M. Landis
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Patent number: 4090919Abstract: A water-insoluble tannin preparation is obtained by covalent binding or physical adsorption of tannin onto a water-insoluble, hydrophilic carrier. The preparation has a specific affinity for proteins and can be used as an adsorbent for purification, isolation and/or separation of proteins (e.g., Enzymes, albumin, globulin, hormonal proteins) from a mixture of compounds. Further, the water-insoluble tannin preparation having a catalytically active enzyme absorbed thereon can be used as a heterogeneous catalyst to induce enzymatic reactions.Type: GrantFiled: January 19, 1977Date of Patent: May 23, 1978Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Ichiro Chibata, Tetsuya Tosa, Takao Mori, Taizo Watanabe, Ryujiro Sano, Yuhsi Matuo