Abstract: New carboxylic acid derivatives are proposed for use as agents in the treatment or prevention of arteriosclerosis. 1-(p-chlorophenoxy)-3-(N-phenyl-N-carbomethoxymethylamino)-2-propanol is a typical compound.

Abstract: An N-substituted carboxylic acid amide of the formula ##STR1## wherein A is a valency bond or an oxygen or sulphur atom or a methylene, ethylene, vinylene, ethyleneoxa or ethylenethia radical,V is a trivalent hydrocarbon radical containing up to 4 carbon atoms,R.sub.1 and R.sub.2 each independently is hydrogen, a halogen atom, a hydroxyl group or an alkyl or alkoxy radical,R.sub.3 is hydrogen, a hydroxyl group or an alkoxy radical,Y is an alkylene radical containing up to 3 carbon atoms,X is a valency bond or a divalent aliphatic hydrocarbon radical containing up to 6 carbon atoms, andD is a hydroxymethyl, formyl, free or esterified carboxyl or an N-substituted carbamoyl radical, or a physiologically compatible salt thereof, characterized by hypoglycaemic and hypolipidaemic activity.

Abstract: The invention relates to 3,4-Dihydro-2H-isoquinoline-1-ones and a process for preparing them.The compounds have an antiarrhythmic activity and are suitable for treating disturbance of the cardiac rhythm.