Aromatic Patents (Class 562/405)
  • Patent number: 10278394
    Abstract: Compounds formed by combining a carboxylic acid herbicide with N—((C1-C16) alkyl or arylalkyl) tri((C1-C16) alkyl)ammonium hydroxide have herbicidal activity on an acid equivalent basis at least as active as the commercially used carboxylic acid herbicide salts, but are less volatile.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: May 7, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Vincent J. Kramer, David G. Ouse, Norman R. Pearson, Holger Tank, Mark W. Zettler
  • Patent number: 9969668
    Abstract: This invention generally relates to the production of free fatty acids and/or derivatives thereof, e.g. fatty acid alkyl esters, from soapstock comprising soaps (salts of fatty acids). In alternative embodiments, the invention provides methods and industrial processes for generating free fatty acids and/or fatty acid derivatives from a soapstock comprising soaps by combining the feedstock with one or more reactants to form a reaction mixture and reacting the mixture at a temperature and pressure sufficient to provide for the acidification of the soaps.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: May 15, 2018
    Assignee: INVENTURE RENEWABLES, INC.
    Inventors: William W. Berry, William Rusty Sutterlin, Mark G. Tegen, Nathan Killingsworth
  • Patent number: 9839217
    Abstract: Compounds formed by combining a carboxylic acid herbicide with N—((C1-C16) alkyl or arylalkyl) tri((C1-C16) alkyl)ammonium hydroxide have herbicidal activity on an acid equivalent basis at least as active as the commercially used carboxylic acid herbicide salts, but are less volatile.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: December 12, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Vincent J. Kramer, David G. Ouse, Norman R. Pearson, Holger Tank, Mark W. Zettler
  • Patent number: 9737560
    Abstract: A method of production and composition of a humic substances-based topical gel that contains a high concentration of polymerized humic substances in the form of polyelectrolyte-enhanced biopolymers, allowing for targeted application of gel to skin. A method of production consists of selection of humic substances containing material, extraction of humic substances from the material, polymerization of humic substances, and further processing for product preservation. Such humic substances based material may be derived from brown coal, such as leonardite or lignite, or peat. An extraction technique for extraction of the humic substances is an alkali extraction method. Such a resulting composition may contain sodium silicate as a gelling agent for ease of application, and in some embodiments a preservative or combination of preservatives for shelf life. Such a humic substances-based topic gel is water soluble, allowing for in-home application and ability to discard through washing down a household drain.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: August 22, 2017
    Assignee: BlackBalm, LLC
    Inventors: Alexander I. Shulgin, Jeffrey L. Sangalli
  • Patent number: 9056818
    Abstract: Compounds according to formula (IA): may be efficiently prepared by the disclosed process.
    Type: Grant
    Filed: July 29, 2010
    Date of Patent: June 16, 2015
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: Fausto Pivetti, Maria Gioia Fornaretto, Marco Re
  • Publication number: 20150126773
    Abstract: Synthetic alkylated graphenes of well chosen structure are prepared and used for mimicking indigenous asphaltenes. The mixtures can be used as multiphase flow test fluids in general and specifically in the Oil and gas industry.
    Type: Application
    Filed: April 25, 2013
    Publication date: May 7, 2015
    Inventor: Vincent Olivier Pauchard
  • Publication number: 20150073131
    Abstract: The present invention is directed generally to a method of production of value-added, biobased chemicals from lignin sources, including waste lignin. A method of producing biobased aromatic chemicals, biobased aromatic fuels, and/or lignin residues from lignin is also described herein.
    Type: Application
    Filed: March 11, 2013
    Publication date: March 12, 2015
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Patent number: 8969554
    Abstract: Disclosed are compounds exhibiting sufficient herbicidal activity at low application dosage when they are applied to soils and foliage, and an agrochemical composition using the same, in particular herbicides. The compounds are triazine derivatives represented by following Formula 1 or salts thereof, and the herbicides containing them: [Chem. 28] wherein in the formula, R1 represents a hydrogen atom; a C1-C12 alkyl group; a C2-C6 alkenyl group, etc., R2 represents a C1-C12 alkyl group, etc., Y and Z represent an oxygen atom or a sulfur atom, and A represents a 5- or 6-membered cyclic group which may contain a nitrogen atom, an oxygen atom, or a sulfur atom.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: March 3, 2015
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Atsushi Shibayama, Ryu Kajiki, Masami Kobayashi, Takashi Mitsunari, Atsushi Nagamatsu
  • Publication number: 20150057253
    Abstract: The present invention relates to alkyl derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Application
    Filed: August 20, 2014
    Publication date: February 26, 2015
    Inventors: Wenkui K. Fang, Ken Chow, Evelyn G. Corpuz
  • Publication number: 20150057456
    Abstract: The present application relates to an improved process for the preparation of (S)-equol (1). The present application also relates to novel intermediates of formula (7), (7A), (8) and (9) and their use for the synthesis of (5)-equol.
    Type: Application
    Filed: March 27, 2013
    Publication date: February 26, 2015
    Inventors: Vilas Hareshwar Dahanukar, Syam Kumar Unniaran Kunhimon, Upadhya Timmana, Abir Kumar Pal, Mahendar Macha, Venkata Madhubabu Meesala, Krishna Mohan Thalabathula, Shankar Ramanathan
  • Publication number: 20150045328
    Abstract: The present invention relates to aryl oxy derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
    Type: Application
    Filed: August 6, 2014
    Publication date: February 12, 2015
    Inventors: Wenkui K. Fang, Ken Chow, Evelyn G. Corpuz
  • Patent number: 8921386
    Abstract: A drug substance with a pharmaceutically acceptable organic acid addition salt of an opioid wherein said organic acid is selected from Structure A: wherein R1-R4 are independently selected from H, alkyl or substituted alkyl of 1-6 carbons, adjacent groups may be taken together to form a cyclic alkyl, cyclic alkyl-aryl, or cyclic aryl moiety; R5 is selected from H, or an alkali earth cation; R6 and R7 are independently selected from H, alkyl of 1-6 carbons, an alkali earth cation, and aryl of 6 to 12 carbons, in a number sufficient to complete the valence bonding of X, and wherein X is selected from nitrogen, oxygen or sulfur; and wherein the drug substance has a morphology selected from amorphous and crystalline.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: December 30, 2014
    Assignee: Pisgah Laboratories, Inc.
    Inventors: Clifford Riley King, Stephen G. D'Ambrosio, David W. Bristol, Michael L. English
  • Patent number: 8883351
    Abstract: The formation method of graphene includes the steps of forming a layer including graphene oxide over a first conductive layer; and supplying a potential at which the reduction reaction of the graphene oxide occurs to the first conductive layer in an electrolyte where the first conductive layer as a working electrode and a second conductive layer with a as a counter electrode are immersed. A manufacturing method of a power storage device including at least a positive electrode, a negative electrode, an electrolyte, and a separator includes a step of forming graphene for an active material layer of one of or both the positive electrode and the negative electrode by the formation method.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: November 11, 2014
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventors: Hiroatsu Todoriki, Yumiko Saito, Takahiro Kawakami, Kuniharu Nomoto, Mikio Yukawa
  • Patent number: 8835409
    Abstract: 3-Alkenyl-6-halo-4-aminopicolinic acids and their derivatives are potent herbicides demonstrating a broad spectrum of weed control.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: September 16, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Joseph D. Eckelbarger, Jeffrey B. Epp, Paul R. Schmitzer, Thomas L. Siddall
  • Patent number: 8815919
    Abstract: The invention relates to oxadiazole compounds of formula I. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: August 26, 2014
    Assignee: Merck Serono SA
    Inventors: Anna Quattropani, Cyril Montagne, Wolfgang Sauer, Stefano Crosignani, Agnès Bombrun
  • Patent number: 8802892
    Abstract: The present invention relates to compounds of formula I, which are functionalized phenolic compounds, and polymers formed from the same. Ar—[O—(X)p—R?]q??I Polymers formed from the functionalized phenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: August 12, 2014
    Assignee: Bezwada Biomedical, LLC
    Inventor: Rao S Bezwada
  • Publication number: 20140206537
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: March 25, 2014
    Publication date: July 24, 2014
    Applicant: DOW AGROSCIENCES LLC
    Inventors: James E. Hunter, William C. Lo, Gerald B. Watson, Akshay Patny, Gary D. Gustafson, Dan Pernich, William K. Brewster, Debra L. Camper, Beth Lorsbach, Michael R. Loso, Thomas C. Sparks, Hemant Joshi, Adiraj Mandaleswaran, Ramadevi Sanam, Rambabu Gundla, Pravin S. Iyer
  • Patent number: 8784520
    Abstract: Methods of treating a plurality of particles involve functionalizing a plurality of microscale diamond particles by covalently bonding one or more molecular groups selected from OH functional groups, —COOH functional groups, —R—COOH functional groups, wherein R includes alkyls, -Ph-COOH functional groups, wherein Ph includes phenolics, polymers, oligomers, monomers, glycols, sugars, ionic functional groups, metallic functional groups, and organo-metallic functional groups to outer surfaces of at least some particles of the plurality of microscale diamond particles. A stability of the functionalized plurality of microscale diamond particles in dispersion is increased as compared to a plurality of microscale diamond particles that has not been functionalized.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: July 22, 2014
    Assignee: Baker Hughes Incorporated
    Inventors: Soma Chakraborty, Gaurav Agrawal
  • Patent number: 8779185
    Abstract: A process and apparatus for manufacture of aromatic carboxylic acids comprises a liquid phase oxidation of aromatic hydrocarbon feed materials and treatment of a high pressure off-gas from the liquid phase oxidation to separate water and reaction solvent and purification of impure aromatic carboxylic acid products wherein a purification liquid includes water from off-gas treatment.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: July 15, 2014
    Assignee: BP Corporation North America Inc.
    Inventor: Thomas M. Bartos
  • Patent number: 8778840
    Abstract: The present invention relates to novel soluble liquid (SL) formulations comprising A) quinclorac ammonium salts of formula I wherein R1, R2, R3 and R4 are independently hydrogen or optionally substituted alkyl, and B) a solvents of formula IIa wherein R5 is alkyl; A is alkylene or oxyalkylene; and m is 0, 1, 2 or 3; and/or a solvent of formula IIb HO—B—OH??(IIb) wherein B is a straight-chain or branched alkylene or alkyleneoxyalkylene or alkyleneoxyalkyleneoxyalkylene.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: July 15, 2014
    Assignee: BASF SE
    Inventors: Rainer Berghaus, Terrance Cannan, Joseph Zawierucha, Glenn W. Oliver
  • Publication number: 20140171308
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: Dow AgroSciences LLC
    Inventors: William C. Lo, James E. Hunter, Gerald B. Watson, Akshay Patny, Pravin S. Iyer, Joshodeep Boruwa
  • Publication number: 20140171314
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: Dow AgroSciences LLC
    Inventors: William C. Lo, James E. Hunter, Gerald B. Watson, Akshay Patny, Pravin S. Iyer, Joshodeep Boruwa
  • Publication number: 20140171312
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: Dow AgroSciences LLC
    Inventors: William C. Lo, James E. Hunter, Gerald B. Watson, Akshay Patny, Pravin S. Iyer, Joshodeep Boruwa
  • Publication number: 20140171309
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: DOW AGROSCIENCES LLC
    Inventors: William C. Lo, James E. Hunter, Gerald B. Watson, Akshay Patny, Pravin S. Iyer, Joshodeep Boruwa
  • Patent number: 8742005
    Abstract: The present invention relates to an acrylate-based compound that includes an organic acid having two or more acrylate groups and one or more phenolic acid structures in one molecule, and a photosensitive composition including the same. It is possible to shorten a developing time in a photolithography process without damaging photosensitivity by using the photosensitive composition according to the present invention.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: June 3, 2014
    Assignee: LG Chem, Ltd.
    Inventors: Keon Woo Lee, Sang Kyu Kwak, Changsoon Lee, Hyehyeon Kim
  • Publication number: 20140135399
    Abstract: Novel polymorphic forms and salts of 1-(3?,4?-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid are useful for the prevention or treatment of Alzheimer's Disease.
    Type: Application
    Filed: January 23, 2014
    Publication date: May 15, 2014
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Fausto Pivetti, Maurizio Delcanale, Stefano Luca Giaffreda, Marco Curzi
  • Patent number: 8710261
    Abstract: The present invention relates to Compounds having the structure of Formula I: wherein n is an integer from 1 to 5; R1 is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, alkoxy, aryloxy, alkenyloxy or alkynyloxy; R2 is alkenyl, allcynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, NR4R5, —NHC(?Y)R4, —NHC(?Y)NR5R?, —NHC(?O)OR4, —NHSO2R4, C(?Y)NR4R5, C(?O)OR6 [wherein Y is oxygen or sulphur], OR5, —O(C?O)NR4R5, O-acyl, S(O)mR4, —SO2N(R4)2, cyano, amidino or guanidino [wherein R4 is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, heteroaryl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl and m is an integer 0-2; R5 is hydrogen or R4; Rx is R4 or —SO2N(R4)2 and R6 is hydrogen, alkyl, cycloalkyl, aralkyl, heteroarylalkyl, heterocyclylalkyl or cycloalkylalkyl]; R3 is hydrogen, fluorine, alkyl, cycloalkylalkyl or aralkyl; A is OH, OR4, —OC(?O)NR4R5, O-acyl, NH2, NR4R5, —NHC(?Y)R4, —NHC(?Y)NR5Rx, —NHC(?O)OR4, —NHSO2R4, and to processes for t
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: April 29, 2014
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Venkata P. Palle, Viswajanani Jitendra Sattigeri, Manoj Kumar Khera, Sreedhara Rao Voleti, Abhijit Ray, Sunanda G. Dastidar
  • Patent number: 8680325
    Abstract: The present invention provides a process for preparing 2,5-dihydroxyterephthalic acid which comprises reacting a dialkali metal salt of hydroquinone with carbon dioxide in a reaction medium in the presence of a potassium salt represented by formula (I): CnH2n+1COOK??(I) wherein n is an integer of 1-17. According to the process for preparing 2,5-dihydroxyterephthalic acid of the present invention, 2,5-dihydroxyterephthalic acid can be produced both safely and at a low cost under industrially advantageous conditions. Further, the process according to the present invention causes less damage to reaction equipment and the like.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: March 25, 2014
    Assignee: Ueno Fine Chemicals Industry, Ltd.
    Inventors: Yusuke Kita, Ryoichi Otsuka
  • Patent number: 8669210
    Abstract: This invention relates to a high-strength, aqueous herbicidal concentrate containing the clopyralid dimethylamine salt. The formulation is stable to storage and exhibits lower viscosity than other clopyralid amine salt formulations.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: March 11, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventor: Robert M. Buttimor
  • Patent number: 8669209
    Abstract: Soluble granule formulations of amine salts of pyridine containing carboxylic acids with improved handling properties are provided by an improved process in which the pyridine containing carboxylic acid is partially neutralized with an amine.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: March 11, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Franklin N. Keeney, Neil A. Foster, Martin C. Logan, Maria G. Perry
  • Publication number: 20140058125
    Abstract: There is provided novel fluoro-substituted compounds capable of modulating the G-protein-coupled receptor GPR40, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as type II diabetes, hypertension, ketoacidosis, obesity, glucose intolerance, and hypercholesterolemia and related disorders associated with abnormally high or low plasma lipoprotein, triglyceride or glucose levels.
    Type: Application
    Filed: April 3, 2012
    Publication date: February 27, 2014
    Applicant: SYDDANSK UNIVERSITET
    Inventors: Trond Ulven, Elisabeth Christiansen
  • Patent number: 8633335
    Abstract: A compound represented by the following general formula (I): [R1 to R5 represent hydrogen atom, an alkyl group, or a trialkylsilyl group, X represents —NH—CO—, —CO—NH—, —N(COR6)—CO—, —CO—N(COR7)— (R6 and R7 represent a lower alkoxy group, or a carboxy-substituted phenyl group) etc.; and Z represents —Y—CH(R12)—COOH, —CHO, —CH?CH—COOH, or —COOR13 (Y represents a single bond, —CH2—, —CH(OH)—, —CO—, —CO—NH—, or —CO—NH—CH2—CO—NH—, R12 represents hydrogen atom or a lower alkyl group, and R13 represents hydrogen atom, —CH(R14)—COOH(R14 represents hydrogen atom, a lower alkyl group, or hydroxy group), —[CH2CH2—O]n—CH2—CH2—OH, —CH2—O—[CH2CH2—O]m—CH2—OH, or —[CH(CH3)—CO—O]p—CH(CH3)—COOH (m, n and p represent an integer of 1 to 100))], a salt thereof or an ester thereof, which has a property of being converted into a retinoid after absorption in vivo.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: January 21, 2014
    Assignee: Research Founation Itsuu Laboratory
    Inventors: Hideaki Muratake, Koichi Shudo
  • Patent number: 8624055
    Abstract: Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise solid particles comprising palladium in combination with at least one of antimony, bismuth and gold, and optionally, an additional metal or metalloid component effective to promote activity or selectivity of the palladium and antimony, bismuth or gold for oxidation to aromatic carboxylic acids. A process for oxidizing substituted aromatic feed materials comprises contacting the feed material with oxygen in the presence of such catalytic compositions in a liquid reaction mixture.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: January 7, 2014
    Assignee: BP Corporation North America Inc.
    Inventors: Wayne P. Schammel, Bradley J. Huggins, Matthew A. Kulzick, Philip O. Nubel, Bryan M. Rabatic, Chengxiang Zhou, Victor A. Adamian, William H. Gong, Peter D. Metelski, Jeffrey T. Miller
  • Patent number: 8609142
    Abstract: The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: December 17, 2013
    Assignee: BIND Therapeutics, Inc.
    Inventors: Greg Troiano, Michael Figa, Abhimanyu Sabnis
  • Patent number: 8603945
    Abstract: This disclosure relates to methods and compositions for modulating disease resistance in plants and transgenic plants.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: December 10, 2013
    Assignee: The Regents of the University of California
    Inventors: Colleen Marie Knoth, Thomas Eulgem, Thomas Girke
  • Patent number: 8586761
    Abstract: Provided is a method for selectively demethylating a 2-methoxy group. Specifically provided is a production method of a compound represented by formula (7) below through the following reactions.
    Type: Grant
    Filed: August 23, 2005
    Date of Patent: November 19, 2013
    Assignee: Zeria Pharmaceutical Co., Ltd.
    Inventors: Masaaki Nagasawa, Kazuyasu Asami, Ryu Nakao, Nobuyuki Tanaka, Yoshiyuki Aida
  • Publication number: 20130266859
    Abstract: A graphene oxide used as a raw material of a conductive additive for forming an active material layer with high electron conductivity with a small amount of a conductive additive is provided. A positive electrode for a nonaqueous secondary battery using the graphene oxide as a conductive additive is provided. The graphene oxide is used as a raw material of a conductive additive in a positive electrode for a nonaqueous secondary battery and, in the graphene oxide, the weight ratio of oxygen to carbon is greater than or equal to 0.405.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 10, 2013
    Applicant: SEMICONDUCTOR ENERGY LABORATORY CO., LTD.
    Inventor: SEMICONDUCTOR ENERGY LABORATORY CO. LTD.
  • Publication number: 20130266869
    Abstract: The formation method of graphene includes the steps of forming a layer including graphene oxide over a first conductive layer; and supplying a potential at which the reduction reaction of the graphene oxide occurs to the first conductive layer in an electrolyte where the first conductive layer as a working electrode and a second conductive layer with a as a counter electrode are immersed. A manufacturing method of a power storage device including at least a positive electrode, a negative electrode, an electrolyte, and a separator includes a step of forming graphene for an active material layer of one of or both the positive electrode and the negative electrode by the formation method.
    Type: Application
    Filed: September 28, 2012
    Publication date: October 10, 2013
    Applicant: SEMICONDUCTOR ENERGY LABORATORY CO., LTD.
    Inventors: Hiroatsu TODORIKI, Yumiko SAITO, Takahiro KAWAKAMI, Kuniharu NOMOTO, Mikio YUKAWA
  • Patent number: 8552062
    Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: October 8, 2013
    Assignee: Wellstat Therapeutics Corporation
    Inventors: Shalini Sharma, Reid W. von Borstel, Kirvin L. Hodge
  • Patent number: 8541603
    Abstract: Therapeutic compounds, methods, and compositions are disclosed herein for treating glaucoma and baldness in mammals. The specific compounds are described herein and are modified prostaglandin derivates.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: September 24, 2013
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Todd S. Gac, Vinh X. Ngo
  • Patent number: 8518995
    Abstract: A method for a prevention and/or treatment of irritable bowel syndrome or amelioration of a symptom thereof in a subject, comprises administering to said subject an effective amount of a compound of formula I:
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: August 27, 2013
    Assignee: MediciNova, Inc.
    Inventors: Kazuko Matsuda, Yuichi Iwaki, Kale Ruby
  • Patent number: 8501986
    Abstract: Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: August 6, 2013
    Assignee: Grupo Petrotemex, S.A. de C.V.
    Inventors: Alan George Wonders, Robert Lin, Lee Reynolds Partin, Marcel de Vreede, Wayne Scott Strasser
  • Patent number: 8492442
    Abstract: It is intended to provide a safe composition for treating a disease or condition relating to autonomic nervous activity which has an autonomic nervous control effect; in particular, an effect of enhancing parasympathetic nervous activity. Thus, a medicinal composition, a food or a drink containing L-phenyl lactic acid and/or D-phenyl lactic acid and having an autonomic nervous control effect is provided.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: July 23, 2013
    Assignee: Suntory Holdings Limited
    Inventors: Yoshinori Beppu, Nobuo Tsuruoka, Hajime Komura, Katsuya Nagai
  • Publication number: 20130178632
    Abstract: One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in various transition-metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition-metal-catalyzed reactions, including the range of suitable substrates, number of catalyst turnovers, reaction conditions, and efficiency. For example, improvements have been realized in transition metal-catalyzed: aryl amination reactions; aryl amidation reactions; Suzuki couplings; and Sonogashira couplings. In certain embodiments, the invention relates to catalysts and methods of using them that operate in aqueous solvent systems.
    Type: Application
    Filed: February 15, 2013
    Publication date: July 11, 2013
    Applicant: Massachusetts Institute of Technology
    Inventor: Massachusetts Institute of Technology
  • Publication number: 20130153855
    Abstract: A process comprises combining a Ce (IV) salt with a carbon material comprising CNT or graphene wherein the Ce (IV) salt is selected from a Ce (IV) ammonium salt of a nitrogen oxide acid and is dissolved in a solvent comprising water. The process is conducted under conditions to substantially oxidize the carbon material to produce an oxidized material that is substantially non-conducting. After the oxidation, the Ce (IV) is substantially removed from the oxidized material. This produces a product made by the process. An article of manufacture comprises the product on a substrate. The oxidized material can be formed as a pattern on the substrate. In another embodiment the substrate comprises an electronic device with the oxidized material patterning non-conductive areas separate from conductive areas of the non-oxidized carbon material, where the conductive areas are operatively associated with the device.
    Type: Application
    Filed: December 16, 2011
    Publication date: June 20, 2013
    Applicant: International Business Machines Corporation
    Inventors: Ali Afzali-Ardakani, Bhupesh Chandra, George S. Tulevski
  • Patent number: 8450522
    Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: May 28, 2013
    Assignee: Amgen Inc.
    Inventors: Sean P. Brown, Paul J. Dransfield, Jonathan Houze, Todd J. Kohn, Jiwen Liu, Julio Medina, Vatee Pattaropong, Wang Shen, Marc Vimolratana, Yingcai Wang, Ming Yu, Liusheng Zhu
  • Publication number: 20130115661
    Abstract: A method for utilizing cultivated plant biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from cultivated plant biomass for producing derivative products while minimizing waste products.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 9, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Publication number: 20130116424
    Abstract: A method for utilizing biomass components, namely cellulose, hemicellose, and lignin, and converting them to value-added biobased chemical products is described herein. The present method provides treatments to obtain a plurality of component streams from biomass for producing derivative products while minimizing waste products.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 9, 2013
    Applicant: Thesis Chemistry, LLC
    Inventors: John R. Peterson, Christopher M. Yost, Jian Wu
  • Patent number: 8426636
    Abstract: A sterically bulky stabilizer that is associated non-covalently with a benzimidazolone pigment. The sterically bulky stabilizer compound includes an aromatic acid derivative, and the presence of the sterically bulky stabilizer limits an extent of particle growth and aggregation, to afford nanoscale pigment particles.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: April 23, 2013
    Assignees: Xerox Corporation, National Research Council of Canada
    Inventors: Rina Carlini, Darren Andrew Makeiff
  • Patent number: 8399518
    Abstract: Methods and compositions are disclosed for stimulating weight loss and/or lowering triglyceride levels in an individual mammal in need thereof. In an exemplary method, a pharmaceutical composition comprising a therapeutically effective amount of DITPA, and optionally one or more lipid-reducing agents, is administered to an individual mammal to stimulate weight loss, and/or reduce levels of triglyceride and/or lipoprotein in the mammal.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: March 19, 2013
    Assignees: University of Arizona Office of Technology Transfer, The United States of America as Represented by the Department of Veterans Affairs
    Inventors: Eugene Morkin, Louis R. Bucalo, Steven Goldman