Unsaturated Patents (Class 562/598)
  • Patent number: 10364213
    Abstract: The present invention provides a method for producing ?-hydroxyisobutyric acid amide by hydration of acetone cyanohydrin under the presence of a catalyst composed mainly of manganese oxide using a reactor in which at least two reaction regions are connected in series, the method being characterized by comprising: a step (B) of cyclically supplying at least a portion of a reaction liquid withdrawn from at least one reaction region to a first reaction region (I) in the reactor; and a step (b1) of further cyclically supplying at least a portion of the reaction liquid withdrawn from at least one reaction region to at least one reaction region other than the first reaction region. The method is also characterized in that an oxidizing agent is supplied to at least one reaction region in the reactor.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: July 30, 2019
    Assignee: MITSUBISHI GAS CHEMICAL COMPANY, INC.
    Inventors: Atsushi Kakimi, Takako Uchiyama, Hideho Matsuda, Masaki Takemoto, Katsumi Higuchi
  • Patent number: 10035747
    Abstract: The present invention provides a method for allowing a used inert material that has been subjected to a reaction once, which is disposed of in the background art, to be used again as well as a brand-new one. A method of recovering an inert material of the present invention is characterized by in the fixed-bed reactor, the inert material is loaded in an inert material layer provided between a first-stage catalyst layer and a second-stage catalyst layer, the first-stage catalyst layer is loaded with a first-stage catalyst for producing acrolein from propylene, and the second-stage catalyst layer is loaded with a second-stage catalyst for producing acrylic acid from acrolein, the method comprising the steps of: extracting the inert material from the fixed-bed reactor; washing the extracted inert material; and screening the washed inert material.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: July 31, 2018
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Yasuhiro Mimura, Fumio Munechika, Hisao Kakuta, Motoki Hisanaga, Seiichi Hara
  • Patent number: 9771314
    Abstract: The invention relates to a process for preparing acrylic acid from formaldehyde and acetic acid, comprising (i) providing a gaseous stream S1 comprising formaldehyde, acetic acid and acrylic acid, where the molar ratio of acrylic acid to the sum total of formaldehyde and acetic acid in stream S1 is in the range from 0.005:1 to 0.3:1; (ii) contacting stream S1 with an aldol condensation catalyst in a reaction zone to obtain a gaseous stream S2 comprising acrylic acid.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: September 26, 2017
    Assignee: BASF SE
    Inventors: Marco Hartmann, Lukas Schulz, Nicolai Tonio Woerz, Yong Liu, Till Christian Brueggemann, Michael Lejkowski, Johannes Lieberknecht
  • Patent number: 9290430
    Abstract: Technical grade acrylic acid derived from renewable resources utilizing a homogeneous nickel catalyst system by a process including reacting lactide with acetic acid to form 2-acetoxypropionic acid in the presence of a homogeneous nickel catalyst, pyrolyzing, with or without a catalyst, the 2-acetoxypropionic acid to acrylic acid and acetic acid, condensing and collecting the pyrolysis products in the presence of polymerization inhibitor(s) and purifying the acrylic acid by distillation in the presence of polymerization inhibitor(s). Acrylic acid and methyl acrylate are produced from methyl 2-acetoxypropionate which comes from fermentation derived lactic acid. The disclosed process will produce a “green” (i.e. renewable resources derived) acrylic acid and methyl acrylate ester.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: March 22, 2016
    Assignee: SGA Polymers, LLC
    Inventors: Olan S. Fruchey, Thomas A. Malisezewski, John E. Sawyer
  • Patent number: 9193661
    Abstract: In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of providing a crude product stream comprising the acrylate product and an alkylenating agent. The process further comprises the step of separating at least a portion of the crude product stream to form an alkylenating agent stream and an intermediate product stream. The alkylenating agent stream comprises at least 1 wt % alkylenating agent and the intermediate product stream comprises acrylate product.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: November 24, 2015
    Assignee: Celanese International Corporation
    Inventors: Craig J. Peterson, Josefina T. Chapman, Ilias S. Kotsianis, Sean Mueller, Dick Nagaki, Tianshu Pan
  • Patent number: 9174913
    Abstract: A process for the production of methacrylic acid is described. The process comprises the base catalysed decarboxylation of at least one or a mixture of dicarboxylic acids selected from itaconic, citraconic or mesaconic acid. The decarboxylation is carried out in the range greater than 240 and up to 275° C. to provide high selectivity. The methacrylic acid product may be esterified to produce an ester. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters using the process is also described. Optionally, the process may be preceded with a decarboxylation and, if necessary, a dehydration step on a source of pre-acid such as citric acid or isocitric acid.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: November 3, 2015
    Assignee: Lucite International UK Limited
    Inventors: David William Johnson, Graham Ronald Eastham, Martyn Poliakoff, Thomas Andrew Huddle
  • Publication number: 20150133687
    Abstract: An ?,?-unsaturated aldehyde and/or an ?,?-unsaturated carboxylic acid are prepared by gas phase oxidation of alkene with molecular oxygen over a fixed catalyst bed comprising a bed of hollow cylindrical shaped catalyst bodies having a multimetal oxide active composition. The fixed catalyst bed comprises at least three successive reaction zones; the highest local temperature in the fixed catalyst bed does not occur in the reaction zone closest to the reactor outlet; the highest local temperature in the fixed catalyst bed does not occur in the reaction zone closest to the reactor inlet; and the value WT=(ED?ID)/2 in the reaction zone in which the highest local temperature in the fixed catalyst bed occurs is lower than in the other reaction zones, in which ED is the external diameter and ID is the internal diameter of the shaped catalyst body. The yield of the products of value is enhanced in this way.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Applicant: BASF SE
    Inventors: Josef MACHT, Christian WALSDORFF, Cornelia Katharina DOBNER, Cathrin Alexandra WELKER-NIEUWOUDT, Ulrich HAMMON
  • Publication number: 20150126777
    Abstract: This invention relates to a process of preparing highly pure, non-yellowing (meth)acrylic acid necessary for high-tech applications requiring long-tem color stability in the presence of amines. Process for the preparation of highly pure, non-yellowing (meth)acrylic acid comprising the steps: f) Condensation of a (meth)acrylic acid-containing gas phase obtained via a gas phase oxidation process of a C4-compound to generate an aqueous (meth)acrylic acid solution g) Separation of the (meth)acrylic acid from the aqueous (meth)acrylic acid solution to obtain crude (meth)acrylic acid h) Rectification of the crude (meth)acrylic acid to obtain pure (meth)acrylic acid via a sidestream outlet of the rectification column i) Treatment of the pure (meth)acrylic acid generated in step c) with an ion exchange resin j) Distillation of the (meth)acrylic acid generated in step d).
    Type: Application
    Filed: April 22, 2013
    Publication date: May 7, 2015
    Applicant: EVONIK INDUSTRIES AG
    Inventors: Zhengfeng Zhang, Gerhard Koelbl, Lorenza Sartorelli, Horst Hiltner, Huisheng Wang, Mirko Michel
  • Publication number: 20150119541
    Abstract: A process for the production of methacrylic acid or esters thereof by the base catalysed decarboxylation of at least one dicarboxylic acid selected from itaconic, citraconic or mesaconic acid or mixtures thereof in an aqueous reaction medium is described. The decarboxylation is carried out at a temperature in the range from 200° C. and up to 239° C. The methacrylic acid is isolated from the aqueous reaction medium by a purification process which does not include introducing an organic solvent to the aqueous reaction medium for solvent extraction of the methacrylic acid into an organic phase. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters is also described.
    Type: Application
    Filed: April 26, 2013
    Publication date: April 30, 2015
    Inventors: Graham Ronald Eastham, David William Johnson, Mark Waugh
  • Patent number: 9012686
    Abstract: Technical grade acrylic acid derived from renewable resources utilizing a homogeneous nickel catalyst system by a process including reacting lactide with acetic acid to form 2-acetoxypropionic acid in the presence of a homogeneous nickel catalyst, pyrolyzing, with or without a catalyst, the 2-acetoxypropionic acid to acrylic acid and acetic acid, condensing and collecting the pyrolysis products in the presence of polymerization inhibitor(s) and purfying the acrylic acid by distillation in the presence of polymerization inhibitor(s). Acrylic acid and methyl acrylate are produced from methyl 2-acetoxypropionate which comes from fermentation derived lactic acid. The disclosed process will produce a “green” (i.e. renewable resources derived) acrylic acid and methyl acrylate ester.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: April 21, 2015
    Inventors: Olan S. Fruchey, Thomas A. Malisezewski, John E. Sawyer
  • Publication number: 20150105586
    Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.
    Type: Application
    Filed: December 18, 2014
    Publication date: April 16, 2015
    Inventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin
  • Publication number: 20150094438
    Abstract: A process for the production of methacrylic acid by the base catalysed decarboxylation of at least one dicarboxylic acid selected from itaconic, citraconic or mesaconic acid or mixtures thereof is described. The decarboxylation is carried out at a temperature in the range from 100 to 199° C. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters is also described.
    Type: Application
    Filed: April 26, 2013
    Publication date: April 2, 2015
    Inventors: Graham Ronald Eastham, David William Johnson, Mark Waugh
  • Publication number: 20150080604
    Abstract: Described herein are methods for preparing acrylic acid from biobased starting materials, e.g., ethanol.
    Type: Application
    Filed: September 16, 2014
    Publication date: March 19, 2015
    Inventor: JOSHUA LENSBOUER
  • Publication number: 20150065746
    Abstract: To address the problem of insufficient biodegradability of perfluorinated surfactants, the present invention provides biodegradable fluorosurfactants derived from olefins having —CHR, —CHRf, —CHF, and/or —CH2 groups, where R is an alkyl group and Rf is a perfluoro or fluroroalkyl group. Preferably, the —CHR, —CHRf, —CHF, and/or —CH2 groups are contained within partially fluorinated alkenes.
    Type: Application
    Filed: August 14, 2014
    Publication date: March 5, 2015
    Inventors: Haridasan K. Nair, Yian Zhai, Andrew J. Poss, Rajiv R. Singh, David Nalewajek
  • Publication number: 20150057455
    Abstract: Methods and systems for producing high purity 3-hydroxypropionic acid (3-HP) from an aqueous medium, such as a fermentation broth, are described. Aqueous 3-HP solution can be purified by flash evaporation wherein the 3-HP is vaporized at an elevated temperature without conversion to acrylic acid. This process can be integrated with downstream processes for producing other chemical and consumer products.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 26, 2015
    Inventors: Cindy HOPPE, Sarah M. HOYT, Robert TENGLER, David DeCOSTER, Bradley HARKRADER, Patrick H. AU-YEUNG, Sanjib BISWAS, Pedro R. VARGAS, II, Raymond P. ROACH, Timothy Charles FRANK
  • Publication number: 20150045577
    Abstract: The present invention relates to a process for hydrolysis of acetone cyanohydrin (ACH) by means of sulphuric acid within the ACH sulpho process for preparation of methacrylic acid (MAA) or methyl methacrylate (MMA).
    Type: Application
    Filed: March 6, 2013
    Publication date: February 12, 2015
    Applicant: Evonik Roehm GmbH
    Inventors: Arndt Selbach, Lorenza Sartorelli, Andreas Perl, Joachim Deinken, Stefanie Sohnemann, Norbert Mnich, Matthias Groemping, Udo Gropp, Thomas Mertz
  • Publication number: 20150045583
    Abstract: A transesterification process produces a (meth)acrylate ester product from a mixture comprising an alkyl(meth)acrylate reactant, an alcohol reactant, a catalyst, and a polymerization inhibitor. The mixture is subjected to reaction conditions sufficient to produce a product (meth)acrylate and a product alcohol, which are different than the reactants.
    Type: Application
    Filed: February 11, 2013
    Publication date: February 12, 2015
    Applicant: ROHM AND HAAS COMPANY
    Inventors: David A. Flosser, Philippe P. Maillot, Nawal K. Sharma, Alejandro Ceron, Mingyu Ye
  • Publication number: 20150031911
    Abstract: The invention relates to a method for producing a shell catalyst that is suitable for producing vinyl acetate monomer (VAM). The invention further relates to a shell catalyst that is obtainable by the method according to the invention and to the use of the shell catalyst according to the invention for producing VAM.
    Type: Application
    Filed: February 19, 2013
    Publication date: January 29, 2015
    Applicant: CLARIANT PRODUKTE (DEUTSCHLAND) GMBH
    Inventors: Gerhard Mestl, Peter Scheck, Alfred Hagemeyer, Carolin Fischer, Roman Bobka
  • Patent number: 8933270
    Abstract: The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), cyclooxygenase-II (COX-2) and an analgesic, such as aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy EPA or DHA compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- or tri-hydroxy derivatives of EPA or DHA (resolvins) that diminish, prevent, or eliminate inflammation or PMN migration, for example. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: January 13, 2015
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Bruce D. Levy
  • Patent number: 8933179
    Abstract: A method of producing a compound of formula (i): wherein R=H or CH3 the method comprising exposing a source of a compound of formula (ii) to reaction conditions of temperature and pressure: formula (ii) wherein R is defined as above wherein, when R=CH3, the source of a compound of formula (ii) is exposed to reaction conditions of temperature and pressure while being in a liquid phase.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: January 13, 2015
    Assignee: Lucite International UK Limited
    Inventors: David William Johnson, Graham Ronald Eastham, Martyn Poliakoff, Thomas Andrew Huddle
  • Patent number: 8927769
    Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is to be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: January 6, 2015
    Assignee: UOP LLC
    Inventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin
  • Patent number: 8895683
    Abstract: In one aspect, a process for the preparation of a superabsorbent polymer is described herein. In some embodiments, the process comprises (I) preparing acrylic acid, wherein the process comprises (a1) provision of a fluid F1 having a composition comprising from about 5 to about 20 wt. % of hydroxypropionic acid, salts thereof, or mixtures thereof; from about 0.1 to about 5 wt. % of inorganic salts; from about 0.1 to about 30 wt. % of organic compounds which differ from hydroxypropionic acid; from 0 to about 50 wt. % of solids; and from about 20 to about 90 wt. % of water; (a2) dehydration of said hydroxypropionic acid to give a fluid F2 containing acrylic acid; and (a3) purification of said fluid F2 to give a purified acrylic acid phase comprising acrylic acid having a purity of at least 70 wt. %; and (II) polymerizing the acrylic acid of (I) to form a superabsorbent polymer.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: November 25, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Franz-Felix Kuppinger, Axel Hengstermann, Guido Stochniol, Gunther Bub, Jurgen Mosler, Andreas Sabbagh
  • Publication number: 20140316002
    Abstract: The present disclosure relates to lipid compounds of general formula (I) wherein R1 is chosen from a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, and a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be selected from different substituents; Y is chosen from sulphur, sulfoxide, and sulfone; and X is a carboxylic acid or a derivative thereof, a carboxylic ester, a carboxylic anhydride, or a carboxamide; or a pharmaceutically acceptable salt, complex, or solvate thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising such compounds, and methods of using such compounds such as for treating diseases related to cardiovascular, metabolic, and/or inflammatory diseases.
    Type: Application
    Filed: April 28, 2014
    Publication date: October 23, 2014
    Applicant: PRONOVA BIOPHARMA NORGE AS
    Inventors: Anne Kristin Holmeide, Ragnar HOVLAND, Morten BRÆNDVANG
  • Publication number: 20140288254
    Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.
    Type: Application
    Filed: November 4, 2013
    Publication date: September 25, 2014
    Applicant: Genomatica, Inc.
    Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
  • Patent number: 8841481
    Abstract: The present invention relates to a process for preparing unsaturated aldehydes or unsaturated carboxylic acids by heterogeneous catalytic gas phase oxidation of unsaturated or saturated hydrocarbons, comprising the process steps of: i) providing a gas mixture comprising a saturated hydrocarbon and catalytically dehydrogenating the saturated hydrocarbon in the gas phase to obtain a gas mixture comprising an unsaturated hydrocarbon in a dehydrogenation reactor having a dehydrogenation catalyst material; or ii) providing a gas mixture comprising oxygen and an unsaturated hydrocarbon; iii) catalytically oxidizing the unsaturated hydrocarbon obtained in process step i) or provided in process step ii) in the gas phase to obtain a gas mixture comprising an unsaturated aldehyde in a first oxidation reactor having a first oxidation catalyst material; wherein at least one of the reactors selected from the dehydrogenation reactor, the first oxidation reactor and the second oxidation reactor comprises at least one foam b
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: September 23, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Horst-Werner Zanthoff, Nicole Brausch, Franz-Felix Kuppinger, Jorg Sauer, Andreas Sabbagh, Dennis Fruhling, Markus Weber, Oliver Becker
  • Publication number: 20140275520
    Abstract: The invention provides a process of preparing 4-amino-4-oxobutanoyl peptides and cyclic analogues thereof of Compound I and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: Achillion Pharmaceuticals, Inc.
    Inventors: Avinash Phadke, Akihiro Hashimoto
  • Publication number: 20140271946
    Abstract: Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: ALTRIA CLIENT SERVICES INC.
    Inventors: Gerd Kobal, Georgios D. Karles, Munmaya K. Mishra
  • Publication number: 20140271488
    Abstract: Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity. The compounds further provide a novel method for obtaining candidate therapeutic agents for prevention, treatment or diagnosis of diseases.
    Type: Application
    Filed: September 7, 2012
    Publication date: September 18, 2014
    Applicant: The Scripps Research Institute
    Inventors: Glenn C. Micalizio, Thomas Kodadek, Mohosin Sarkar
  • Patent number: 8829134
    Abstract: A process for transporting a liquid monomer phase which has been withdrawn from a storage vessel and comprises methacrylic monomers to an extent of ?90% by weight, in a tank truck or in a tanker ship, in which the liquid monomer phase is subjected to a separating operation on the route from the storage vessel into the tank of a tank truck or of a tanker ship in order to separate polymer of the monomer present in dissolved form in the liquid monomer phase.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: September 9, 2014
    Assignee: BASF SE
    Inventors: Joerg Heilek, Ulrich Hammon, Volker Schliephake, Klaus Joachim Mueller-Engel, Till Blum
  • Publication number: 20140239231
    Abstract: An environmentally beneficial process for the production of fuels and chemicals employs carbon dioxide from a natural source or from an artificial chemical source that would otherwise be discharged into the environment. The carbon dioxide is converted to formic acid and the formic acid is then non-biologically converted to fuels and/or chemicals without the intermediate process of hydrogenating the formic acid to methanol or reacting the formic acid with ammonia to form formamide. In the present process, formic acid is converted to one of seven primary feedstocks: formaldehyde, acrylic acid, methane, ethylene, propylene, syngas, and C5-C7 carbohydrates. The formaldehyde, acrylic acid, methane, ethylene, propylene, syngas and/or short chain carbohydrates can either be used directly, or can be converted into a wealth of other products.
    Type: Application
    Filed: February 24, 2013
    Publication date: August 28, 2014
    Applicant: DIOXIDE MATERIALS, INC.
    Inventors: Richard I. Masel, Zheng Richard Ni, Qingmei Chen, Brian A. Rosen
  • Publication number: 20140228571
    Abstract: In a method of stabilizing acrylic compounds, a liquid phase containing at least one acrylic compound is mixed with at least one metal and at least one ligand. The acrylic compound can be acrylic acid, methacrylic acid, and their respective esters. The metal can be copper, manganese, and cerium. The ligand can be a quinoline compound of formula (I), an N-oxide of a compound of formula (I), 2,2?-bis(2,3-dihydro-3-oxoindolylidene), or an aliphatic y-dentate ligand with y being 2-6 and comprising at least two nitrogen atoms joined by aliphatic or aromatic C1-C4 bridges comprising y-2 further coordinating nitrogen atoms or heteroatoms: where X is OH, NH2, O—(C1-C4)-alkyl, O—C(O)—(C1-C4)-alkyl, or O—C(O)-phenyl; R1 is H, or (C1-C4)-alkyl; R2 is H, (C1-C4)-alkyl, Cl, Br, or SO3H; and R3 is H, Cl or Br.
    Type: Application
    Filed: December 12, 2013
    Publication date: August 14, 2014
    Applicant: BASF SE
    Inventors: Tobias Johannes KORN, Peter Zurowski, Thorsten Friese, Sylke Haremza, Ulrich Jäger, Steffen Rissel, Volker Schliephake
  • Publication number: 20140194559
    Abstract: The invention concerns a formulation and method which allow for the efficient delivery of antipolymerants of low solubility into processes for the production of ethylenically unsaturated monomers, and associated process streams, and which avoid the potential health and safety problems and economic disadvantages which are associated with the methods of the prior art and facilitate the safe and efficient production of these monomers. Specifically, the invention provides an antipolymerant composition for the prevention of unwanted polymerisation reactions during the production and processing of ethylenically unsaturated compounds, the composition comprising a concentrated liquid formulation, wherein said concentrated liquid formulation is a suspension concentrate which comprises: (a) at least one compound selected from the group comprising phenols, quinones, thiazines, hydroxylamines and aromatic amines; (b) at least one dispersing agent; and (c) at least one polar or non-polar liquid carrier.
    Type: Application
    Filed: August 20, 2012
    Publication date: July 10, 2014
    Applicant: NuFarm UK Limited
    Inventors: Peter Price, Guillaume Duchamp, Angela Jane Glossop, Andrew Nigel Fawbert, Stephanie Mary Dwyer
  • Publication number: 20140179942
    Abstract: The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second enzyme system which is capable of converting formic acid into aliphatic carboxylic acids having a chain length of five or more carbon atoms. Also described are various methods for producing oil, as well as other aspects of the invention.
    Type: Application
    Filed: July 13, 2012
    Publication date: June 26, 2014
    Applicant: VERDANT BIOPRODUCTS LIMITED
    Inventor: Irene Finnegan
  • Publication number: 20140162345
    Abstract: Processes for converting lignocellulose to feedstock and downstream products are disclosed. The processes may include acid treatment of lignocellulose to produce a fermentation feedstock. In various instances, the processes include recovery or recycling of acid, such as recovery of hydrochloric acid from concentrated and/or dilute streams. Downstream products may include acrylic acid-based products such as diapers, paper and paper-based products, ethanol, biofuels such as biodiesel and fuel additives, and detergents.
    Type: Application
    Filed: April 2, 2012
    Publication date: June 12, 2014
    Inventor: Aharon Eyal
  • Patent number: 8748545
    Abstract: The present invention relates to the manufacture of bioresourced polymer-grade acrylic acid from glycerol. The polymer grade acrylic acid produced has limited content of certain impurities harmful to polymerization processes, such as, total aldehydes, protoanemonin, maleic anhydride and nonphenolic polymerization inhibitors. The invention also relates to the use of the bioresourced acrylic acid obtained for manufacture of superabsorbents or for manufacture of polymers or copolymers using amide or ester derivatives of the bioresourced acrylic acid.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: June 10, 2014
    Assignee: Arkema France
    Inventors: Jean-Francois Devaux, Michel Fauconet, Denis Laurent
  • Publication number: 20140147481
    Abstract: The invention provides novel compositions based on a structure designated as “Honaucin A”, including Honaucin A variants and analogs, and pharmaceutical compositions, liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used as bacterial quorumsensing inhibitors. Accordingly, in alternative embodiments the compositions of the invention are used as anti-bacterial agents.
    Type: Application
    Filed: June 3, 2011
    Publication date: May 29, 2014
    Applicants: UNIVERSITY OF RHODE ISLAND RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William Gerwick, Lena Gerwick, Huykjae Choi, Francisco Villa, Jennifer Smith, David C Rowley
  • Patent number: 8729299
    Abstract: In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of reacting a reaction mixture comprising an alkanoic acid, an alkylenating agent, and oxygen over a catalyst and under conditions effective to form a crude acrylate product. Preferably, the reaction mixture comprises from 0.5 wt % to 10 wt % oxygen. The crude acrylate product comprises acrylate product and alkylenating agent. The process further comprises the step of separating at least a portion of the crude product to form at least one alkylenating agent stream and at least one purified acrylate product stream. The purified acrylate product stream comprises acrylate product.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: May 20, 2014
    Assignee: Celanese International Corporation
    Inventors: Sean Mueller, Josefina Chapman, Craig Peterson, Dick Nagaki
  • Publication number: 20140135526
    Abstract: Methods of obtaining mutant nucleic acid sequences that demonstrate elevated oxaloacetate a-decarboxylase activity are provided. Compositions, such as genetically modified microorganisms that comprise such mutant nucleic acid sequences, are described, as are methods to obtain the same.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 15, 2014
    Applicant: OPX Biotechnologies, Inc.
    Inventor: Michael D. Lynch
  • Publication number: 20140121399
    Abstract: The polymerization of monomers may be at least partially reduced or inhibited by introducing an effective amount of an additive. The additive may be or include a first compound: where: R1 and R2 may be or include an alkyl group, an aryl group, an alkyl group having a heteroatom, an aryl group having a heteroatom, and combinations thereof. The hetero atom may be or include sulfur, nitrogen and/or oxygen. R1 may be the same or different from R2. The polymerizable monomers may be or include, but are not limited to styrene, butadiene, isoprene, acrylic acid, acrylonitrile, vinyl acetate, and combinations thereof.
    Type: Application
    Filed: October 25, 2012
    Publication date: May 1, 2014
    Applicant: BAKER HUGHES INCORPORATED
    Inventors: Hua Mo, Roger D. Metzler
  • Patent number: 8704000
    Abstract: PROBLEM There is provided a melting method of (meth)acrylic acid crystal which is capable of providing a higher quality of (meth)acrylic acid without carrying out an additional purification treatment to (meth)acrylic acid obtained by a crystallization operation accompanied by melting of (meth)acrylic acid. In addition, there is provided a simple method for adjusting a content of polymerization inhibitor in a product (meth)acrylic acid. SOLUTION In the crystallization method melting (meth)acrylic acid crystal while wetting with the crystalline molten liquid, a polymerization inhibitor is added to a molten liquid melted after initiation of melting, and all of crystal is melted while circulating and feeding the molten liquid containing said polymerization inhibitor to the crystal.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: April 22, 2014
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Kazuhiko Sakamoto, Koji Ueno, Yoshitake Ishii, Harunori Hirao, Satoshi Nakagawa
  • Publication number: 20140107377
    Abstract: This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using propionyl-CoA as an intermediate. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing acrylate by culturing the microorganisms. Also provided are microorganisms and methods for converting propionyl-CoA and propionate to 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3-HP) and poly-3-hydroxypropionate.
    Type: Application
    Filed: October 15, 2012
    Publication date: April 17, 2014
    Applicant: THE PROCTER & GAMBLE COMPANY
    Inventors: Jun Xu, Phillip Richard Green, Charles Winston Saunders, Juan Estaban Velasquez
  • Patent number: 8685682
    Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: April 1, 2014
    Assignee: E I du Pont de Nemours and Company
    Inventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K Picataggio, James John Ragghianti, John E Seip, Zhixiong Xue, Narendra S Yadav, Hongxiang Zhang, Quinn Qun Zhu
  • Publication number: 20140087978
    Abstract: A method of converting an inactive biocide into an active biocide comprises: contacting the inactive biocide with an activating agent, wherein the activating agent is capable of chemically reacting with the inactive biocide; and causing or allowing a chemical reaction to take place between the inactive biocide and the activating agent, wherein the chemical reaction produces the active biocide. The methods can also include deactivating the active biocide via a chemical reaction between the active biocide and a deactivating agent.
    Type: Application
    Filed: September 27, 2012
    Publication date: March 27, 2014
    Applicant: HALLIBURTON ENERGY SERVICES, INC
    Inventor: Jay P. DEVILLE
  • Publication number: 20140058133
    Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.
    Type: Application
    Filed: June 11, 2013
    Publication date: February 27, 2014
    Inventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin
  • Publication number: 20140051886
    Abstract: The present invention relates to a process for preparing methacrylic acid based on the hydrolysis of methacrylic esters.
    Type: Application
    Filed: April 24, 2012
    Publication date: February 20, 2014
    Applicant: EVONIK RÖHM GmbH
    Inventors: Dirk Broell, Hermann Siegert, Horst Hiltner, Thomas Krauss
  • Publication number: 20140039216
    Abstract: The present invention relates to an improved process for the preparation of Fesoterodine and pharmaceutically acceptable salts thereof. The present invention particularly relates to a process for the preparation of fesoterodine and pharmaceutically acceptable salts thereof which involves use and preparation of R(+)benzyl tolterodine and fumarate salt of R(+)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol.
    Type: Application
    Filed: November 11, 2011
    Publication date: February 6, 2014
    Applicant: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Jayaraman Venkat Raman, Samir Patel, Indrajit Thakor, Mahesh Ladani, Chetan Patil, Ronak Patel, Prashant Raval, Viral Parekh, Hiral Shah
  • Patent number: 8642803
    Abstract: A process for preparing an alkali metal or alkaline earth metal salt of an ?,?-ethylenically unsaturated carboxylic acid, wherein a) an alkene, carbon dioxide and a carboxylation catalyst are converted to an alkene/carbon dioxide/carboxylation catalyst adduct, b) the adduct is decomposed to release the carboxylation catalyst with an auxiliary base to give the auxiliary base salt of the ?,?-ethylenically unsaturated carboxylic acid, c) the auxiliary base salt of the ?,?-ethylenically unsaturated carboxylic acid is reacted to release the auxiliary base with an alkali metal or alkaline earth metal base to give the alkali metal or alkaline earth metal salt of the ?,?-ethylenically unsaturated carboxylic acid. Salts of ?,?-ethylenically unsaturated carboxylic acids, such as sodium acrylate in particular, are required in large amounts, for example, for production of water-absorbing resins.
    Type: Grant
    Filed: March 3, 2011
    Date of Patent: February 4, 2014
    Assignee: BASF SE
    Inventors: Michael Limbach, Jeremie Miller, Stephan Schunk
  • Publication number: 20140031501
    Abstract: A method of extracting (meth)acrylic acid from an aqueous reaction medium into an organic phase in contact therewith is described. The aqueous reaction medium is formed from at least one base catalyst and at least one dicarboxylic acid selected from maleic, fumaric, malic, itaconic, citraconic, mesaconic, and citramalic acid or mixtures thereof in aqueous solution and contains the base catalysed decarboxylation products of the base catalysed reaction. The method includes either the addition of at least one of the said dicarboxylic acids and/or a pre-cursor thereof to the aqueous reaction medium to enhance the solvent extraction of the (meth)acrylic acid into the organic solvent or maintaining the level of base catalyst to dicarboxylic acid and/or pre-cursor at a sub-stoichiometric level during the extraction process. The method extends to a process of producing (meth)acrylic acid, its esters and polymers and copolymers thereof.
    Type: Application
    Filed: February 8, 2012
    Publication date: January 30, 2014
    Applicant: LUCITE INTERNATIONAL UK LIMITED
    Inventors: David William Johnson, Graham Ronald Eastham, Martyn Poliakoff, Thomas Andrew Huddle
  • Patent number: 8614046
    Abstract: A salt represented by the formula (I-Pa): wherein Xpa represents a single bond or a C1-C4 alkylene group, Rpa represents a single bond, a C4-C36 divalent alicyclic hydrocarbon group or a C6-C36 divalent aromatic hydrocarbon group, and one or more methylene groups in the divalent alicyclic hydrocarbon group can be replaced by —O— or —CO—, Ypa represents a polymerizable group, and Zpa+ represents an organic cation.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: December 24, 2013
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Koji Ichikawa, Masako Sugihara, Yuko Yamashita
  • Patent number: 8604238
    Abstract: A method for producing (meth)acrylic acid relevant to the present invention has the step for producing (meth)acrylic acid-containing gas by subjecting raw material gas to a catalytic vapor phase oxidation reaction in a reactor for catalytic vapor phase oxidation; and the step for obtaining a (meth)acrylic acid solution by introducing (meth)acrylic acid-containing gas thus produced to an absorption tower and separating non-condensable gas from (meth)acrylic acid-containing gas, and it is an object to provide a method for obtaining a high concentration acrylic acid solution stably by controlling temperature of (meth)acrylic acid-containing gas just before being supplied to the absorption tower, regardless of temperature fluctuation of gas discharged from the reactor for catalytic vapor phase oxidation.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: December 10, 2013
    Assignee: Nippon Shokubai Co. Ltd.
    Inventor: Masaharu Oba