Acyclic Patents (Class 562/512)
  • Patent number: 11078148
    Abstract: Some embodiments of the invention include methods of using a compound (e.g., Formula (I)) for the reduction of carbon dioxide to formate by contacting the carbon dioxide with a composition comprising a compound. In certain embodiments, the source of the carbon dioxide is air or is flue gas. Additional embodiments of the invention are also discussed herein.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: August 3, 2021
    Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Steve P. Cronin, Craig A. Grapperhaus, Robert M. Buchanan, Jacob M. Strain, Joshua M. Spurgeon
  • Patent number: 10858328
    Abstract: According to the present invention, there is provided means for suppressing the occurrence of corrosion on the inner tube side in a heat exchanger and enabling continuous production for a long time period in a process for producing ethylene oxide. An embodiment of the present invention relates to a method for producing ethylene oxide, the method including: supplying a raw material gas including ethylene, molecular oxygen, and a chlorine compound to an ethylene oxidation reactor; subjecting ethylene and molecular oxygen in the raw material gas to catalytic vapor phase oxidation in the ethylene oxidation reactor in the presence of a silver catalyst, and thereby producing a gas including ethylene oxide, water, and a chlorine compound; and cooling a gas to be cooled including water and the chlorine compound using a heat exchanger.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: December 8, 2020
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Shingo Iguchi, Hideto Suzuki
  • Patent number: 10428014
    Abstract: The present invention relates to a compound represented by the general formula (A), a base generator comprising the compound, a base-reactive composition which comprises the base generator and a base-reactive compound, as well as a method for generating a base, etc.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 1, 2019
    Assignees: FUJIFILM Wako Pure Chemical Corporation, Tokyo University of Science Foundation
    Inventors: Nobuhiko Sakai, Kosuke Yanaba, Koji Arimitsu
  • Patent number: 10087476
    Abstract: A process for hydrolyzing a pretreated lignocellulosic feedstock is disclosed herein. The process comprises hydrolyzing the pretreated lignocellulosic feedstock with an enzyme mixture comprising at least cellulase enzymes to produce a hydrolyzed slurry comprising glucose and lignin solids. The hydrolyzing is conducted in the presence of a polymer, such as an aliphatic polyether. A solids-liquid separation is conducted to recover lignin solids from a process stream comprising the lignin solids and the polymer. A process stream is then obtained comprising recovered lignin solids resulting from the solids-liquid separation. Also provided are processes for recovering the polymer from the lignin solids and/or from solution.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: October 2, 2018
    Assignee: IOGEN CORPORATION
    Inventors: Brian E. Foody, Kristin Martens, Patrick J. Foody, Jeffrey S. Tolan
  • Patent number: 9771317
    Abstract: There is provided a process for the preparation of Lacosamide in a particular polymorphic form, which process involves the isolation of a salt of formula I: according to the methods defined in the application.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: September 26, 2017
    Assignees: Cambrex Karlskoga AB, Cambrex Profarmaco Milano
    Inventors: Stefano Radaelli, Giuseppe Zurlo, Lars Eklund, Margus Eek, Ants Maasalu, Malle Schmidt
  • Patent number: 9365596
    Abstract: A two-step pathway for preparing high pure quaternary phosphonium salts is disclosed. In the first step, hydrogen phosphide (PH3) or a higher phosphine reacts with a protonic compound to produce a phosphonium salt, which then reacts with a carbonic acid diester to produce a quaternary phosphonium salt in the second step. On one hand, hydrogen phosphide (PH3) and higher phosphines, including primary phosphines, secondary phosphines, and tertiary phosphines, after neutralization with protonic compound, become sufficiently reactive and can be alkylated by carbonic acid diester to form quaternary phosphonium cations. On the other hand, as an anion-exchange procedure is completely avoided, the process not only gives quaternary phosphonium salts of high purity, but also gives people freedom to design the cation and the anion of a quaternary phosphonium salt synchronously by choosing a preferred phosphine and a protonic compound that can supply a desired anion.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: June 14, 2016
    Assignee: MICROVAST POWER SYSTEMS CO., LTD.
    Inventors: Zhuoqun Zheng, Dawei Shen, Yunhua Nie, Jian Qiu, Yumei Zhang
  • Patent number: 9278929
    Abstract: An improved process or method of synthesis of carfentanil and other potent opioid analgesics of the N-alkyl 4-substituted 4-piperdinylamide class which can be used as morphine substitutes.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: March 8, 2016
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Andrew J Walz, Fu-Lian Hsu
  • Patent number: 9227916
    Abstract: L-valine granules are produced by adding L-glutamic acid to an aqueous solution containing L-valine so that the amount of L-glutamic acid is 0.5% by weight or more relative to the L-valine, dissolving the L-glutamic acid, then adjusting the pH of the aqueous solution to an acidic level and then crystallizing the L-valine.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: January 5, 2016
    Assignee: KYOWA HAKKO BIO CO., LTD.
    Inventors: Hiromu Yoshiura, Hiroshi Nagano
  • Patent number: 9206119
    Abstract: There is provided a process for preparing ?-mercaptocarboxylic acid represented by the following General Formula (3) comprising step of reacting hydrogen sulfide, alkali hydroxide represented by a formula: XOH (X represents Na or K), and unsaturated carboxylic acid represented by the following General Formula (1) under atmospheric pressure to obtain a reaction solution including a compound represented by the following General Formula (2) and step of neutralizing the reaction solution in an acid. An amount of the alkali hydroxide is equal to or greater than total moles of the unsaturated carboxylic acid and the hydrogen sulfide.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: December 8, 2015
    Assignee: MITSUI CHEMICALS INC.
    Inventors: Masayuki Furuya, Tatsuya Ogawa, Takeshi Nishimura
  • Patent number: 9127131
    Abstract: A method of producing a porous molded part includes a mixing process for mixing a granular porous organizer composed of a water-soluble compound, a porous forming assistant agent composed of a polyhydric alcohol, and a cross-linking agent composed of an organic peroxide with a thermoplastic resin composition having a glass transition temperature below 0° C. to obtain a molding material; a cross-linking and forming process for placing the molding material in a molding die and performing a heat press molding thereby progressing coincidentally a cross-linking reaction and a shape forming of a seal face to obtain a molded material; an extracting process for extracting the granular porous organizer from the molded material obtained in the cross-linking and forming process to obtain a porous molded part; and a drying process for drying the porous molded part obtained in the extracting process.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: September 8, 2015
    Assignee: SHACHIHATA INC.
    Inventors: Ikuzo Matsushita, Katsuya Takaichi, Yoshiaki Nagata
  • Patent number: 9029596
    Abstract: A method for producing acrylic acid and/or an ester thereof from a raw material composition containing hydroxypropionic acid and/or an ester thereof, the method including the steps of: (a) evaporating the raw material composition; and (b) dehydrating the evaporated raw material composition by contact with a dehydration catalyst, wherein the total amount of hydroxypropionic acid and/or an ester thereof supplied in the step (b) is controlled to be 70% by mass or more based on 100% by mass of the total amount of hydroxypropionic acid and/or an ester thereof supplied in the step (a).
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: May 12, 2015
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Hiroshi Yoshida, Hisashi Kamei
  • Publication number: 20150104367
    Abstract: According to one embodiment, a catalyst includes a metal ion, and an acyclic ligand having at least one aza-containing moiety, where the ligand is complexed to the metal ion.
    Type: Application
    Filed: October 10, 2013
    Publication date: April 16, 2015
    Applicant: Lawerence Livermore National Security, LLC
    Inventors: William C. Floyd, III, Carlos A. Valdez, Roger Aines, Sarah Baker, Joe H. Satcher, JR.
  • Patent number: 8987509
    Abstract: A process for recovering a volatile carboxylic acid from an aqueous stream containing same comprising the steps of: (a) evaporating the aqueous stream to produce a vapour stream comprising the volatile carboxylic acid that has been vapourized and water vapour, which aqueous stream is produced by a conversion process using a lignocellulosic feedstock as a substrate; (b) contacting the vapour stream with an organic solvent so as to extract the volatile carboxylic acid present in the vapour stream, thereby producing a liquid stream comprising the organic solvent and the volatile carboxylic acid, and a water vapour stream, wherein the organic solvent has an atmospheric boiling point of at least about 150° C. and is insoluble in water; and (c) separating the volatile carboxylic acid from the organic solvent.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: March 24, 2015
    Assignee: Iogen Energy Corporation
    Inventors: Jeffrey S. Tolan, Brian Foody, Vijay Anand, Daphne Wahnon
  • Patent number: 8981146
    Abstract: A process for recovering a volatile carboxylic acid from an aqueous stream comprising same, the process comprising the steps of: (i) steam stripping the carboxylic acid from the aqueous stream, which aqueous stream is produced by a conversion process using a lignocellulosic feedstock as a substrate, the steam stripping comprising contacting the aqueous stream with steam by flowing the aqueous stream and the steam countercurrent to one another, thereby producing a vapor stream comprising vaporized carboxylic acid and steam and a stripped aqueous stream; (ii) extracting the vaporized carboxylic acid with an organic solvent by contacting the vapor stream with the organic solvent to produce (a) a stream comprising the organic solvent and the carboxylic acid and (b) the steam at least substantially depleted of the carboxylic acid, wherein the organic solvent has an atmospheric boiling point of at least about 150° C.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: March 17, 2015
    Assignee: Iogen Energy Corporation
    Inventors: Jeffrey S. Tolan, Brian Foody, Vijay Anand
  • Publication number: 20150072028
    Abstract: The present invention relates to extracts, compounds isolated from Cakile arabica for use in the treatment of ulcer and to pharmaceutical compositions thereof.
    Type: Application
    Filed: September 4, 2014
    Publication date: March 12, 2015
    Applicant: KING SAUD UNIVERSITY
    Inventors: Awaad Amani SHAFEEK, Reham Moustafa EL-MELIGY, Mohammed Sobhy MARZOUK, Shroog Mohamed ALOTAIBY
  • Publication number: 20150064451
    Abstract: A coating method, coated article and coating are provided. The coated article includes a low temperature component, and a graphene coating formed from a graphene derivative applied over the low temperature component. The coating method includes providing a graphene derivative, providing a low temperature component, applying the graphene derivative over the low temperature component, and forming a graphene coating. The graphene coating reduces corrosion and fouling of the low temperature component. The coating includes a graphene derivative, and modified functional groups on the graphene derivative. The modified functional groups increase adherence of the coating on application to a low temperature component.
    Type: Application
    Filed: August 29, 2013
    Publication date: March 5, 2015
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Murali Krishna KALAGA, Arjun BHATTACHARYYA, Rebika Mayanglambam DEVI, Jon Conrad SCHAEFFER, Padmaja PARAKALA, Surinder Singh PABLA
  • Patent number: 8952047
    Abstract: A Nitrate or Nitrite of a Betaine Compound disclosed. Also disclosed are a composition and a supplement formulation comprising at least one constituent selected from the group consisting of a Nitrate, a Nitrite, and both; and a Betaine Compound. The composition and supplement formulation may be formulated to deliver an effective amount of the constituents to prevent the development of nitrate tolerances, to increase bioabsorption of amino acids, or to increase the vasodilative characteristics of amino acids in a human or animal.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: February 10, 2015
    Assignee: ThermoLife International, LLC
    Inventors: Ronald Kramer, Alexander Nikolaidis
  • Publication number: 20150034554
    Abstract: The invention relates to a surface-treated calcium carbonate for binding and bioremediating hydrocarbon-containing compositions, to a method for binding and bioremediating hydrocarbon-containing compositions as well as to the use of surface-treated calcium carbonate for binding and bioremediating hydrocarbon-containing compositions and to a composite material comprising the surface-treated calcium carbonate and a hydrocarbon-containing composition.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 5, 2015
    Inventors: Nicola Di Maiuta, Patrick Schwarzentruber, Michael Skovby
  • Patent number: 8946474
    Abstract: The present invention relates to the crystalline, polymorphic Form X of the calcimimetic compound {4-[(1R,3S)-3-((R)-1-Naphthalen-1-yl-ethylamino)-cyclopentyl]-phenoxy}-acetic acid, to methods of preparation thereof, to methods of characterization thereof by single crystal X-Ray crystallography (XRC), X-Ray Powder diffractometry, attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, Solid State NMR spectroscopy and Differential Scanning Calorimetry (DSC), and to its use. The invention also relates to the preparation of Form X by crystallization from a saturated solution of {4-[(1R,3S)-3-((R)-1-Naphthalen-1-yl-ethylamino)-cyclopentyl]-phenoxy}-acetic acid in a C1-C6 alkyl alcohol, or alternatively by precipitation from a neutralized saponification reaction mixture following the alkaline hydrolysis of a C1-C6 alkyl ester of {4-[(1R,3S)-3-((R)-1-Naphthalen-1-yl-ethylamino)-cyclopentyl]-phenoxy}-acetic acid.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: February 3, 2015
    Assignee: LEO Pharma A/S
    Inventors: Søren Ebdrup, Kim Troensegaard Nielsen, Tanja Maria Greve
  • Publication number: 20140378692
    Abstract: As shown by the following formula (1), after methyl laurate (2 mmol) and water (8 mL) are added to an ammonium pyrosulfate catalyst (5 mol %), a hydrolysis reaction of methyl laurate is carried out by heating for 24 hours at 60° C. while stirring is performed, so that lauric acid can be obtained with a yield of 86%.
    Type: Application
    Filed: December 13, 2012
    Publication date: December 25, 2014
    Inventors: Kazuaki Ishihara, Akira Sakakura, Yoshiki Koshikari
  • Patent number: 8895683
    Abstract: In one aspect, a process for the preparation of a superabsorbent polymer is described herein. In some embodiments, the process comprises (I) preparing acrylic acid, wherein the process comprises (a1) provision of a fluid F1 having a composition comprising from about 5 to about 20 wt. % of hydroxypropionic acid, salts thereof, or mixtures thereof; from about 0.1 to about 5 wt. % of inorganic salts; from about 0.1 to about 30 wt. % of organic compounds which differ from hydroxypropionic acid; from 0 to about 50 wt. % of solids; and from about 20 to about 90 wt. % of water; (a2) dehydration of said hydroxypropionic acid to give a fluid F2 containing acrylic acid; and (a3) purification of said fluid F2 to give a purified acrylic acid phase comprising acrylic acid having a purity of at least 70 wt. %; and (II) polymerizing the acrylic acid of (I) to form a superabsorbent polymer.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: November 25, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Franz-Felix Kuppinger, Axel Hengstermann, Guido Stochniol, Gunther Bub, Jurgen Mosler, Andreas Sabbagh
  • Patent number: 8877811
    Abstract: The present invention is directed to novel diacid derivatives, pharmaceutical compositions comprising the diacid derivatives and methods for the treatment of insulin and non-insulin dependent diabetes mellitus and related disorders comprising administering to a subject in need thereof, the compounds of the present invention.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: November 4, 2014
    Assignee: CIP Kemicals, Corp.
    Inventor: Roberto Iglesias Lores
  • Patent number: 8846898
    Abstract: Nucleoside phosphinoamidite carboxylates and analogs are provided that have the structure of formula (III) wherein A is hydrogen, hydroxyl, lower alkoxy, lower alkoxy-substituted lower alkoxy, halogen, SH, NH2, azide or DL wherein D is O, S or NH and L is a heteroatom-protecting group, unsubstituted hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, or substituted heteroatom-containing hydrocarbyl; B is a nucleobase; and one of R11 and R12 is a blocking group and the other is (IV) or (VI) in which W, X, Y, Z, R1 and n are as defined herein.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: September 30, 2014
    Assignee: Lieure Cornu LLC
    Inventor: Douglas J. Dellinger
  • Publication number: 20140243552
    Abstract: A reactive emulsifier comprising a compound of formula (I), which makes polymerization stability satisfactory and is capable of improving the water resistance etc. of the polymer film to be obtained. In the formula (I), D represents a polymerizable unsaturated group represented by the chemical formula D-1 or D-2; m1 represents a number of 1 or larger; R1 represents an alkyl group having 1 to 12 carbon atoms; m2 represents a number of 0 to 4; and the sum of m1 and m2 is 1 to 5. R2 represents a hydrocarbon group having 6 to 30 carbon atoms; A represents either an alkylene group or a substituted alkylene group which has 2 to 4 carbon atoms; and n is in the range of 0 to 1,000. X represents a hydrogen atom or an anionic hydrophilic group which is —(CH2)a—SO3M etc. R3 represents a hydrogen atom or methyl.
    Type: Application
    Filed: September 18, 2012
    Publication date: August 28, 2014
    Applicant: Dai-ichi Kogyo Seiyaku Co., Ltd.
    Inventors: Asako Ogasawara, Masayuki Hashimoto
  • Publication number: 20140243247
    Abstract: A composition of an oil-soluble ionic detergent that does not contribute metal ions to the composition, and which comprises a quaternary non-metallic pnictogen cation and an organic anion having at least one hydrocarbyl group of sufficient length to impart oil solubility to the detergent, the detergent having a total base number (TBN) to total acid number (TAN) ratio of at least 2:1 imparts ash-free basicity to a lubricant composition.
    Type: Application
    Filed: May 14, 2014
    Publication date: August 28, 2014
    Applicant: The Lubrizol Corporation
    Inventors: Ewan E. Delbridge, Virginia A. Carrick, John K. Pudelski, Matthew D. Giesleman, Christopher L. Friend, Patrick E. Mosier, Michele M. Rogers, Mark T. Tierney
  • Patent number: 8802893
    Abstract: According to a method for producing acetic acid by carbonylation of methanol characterized in that an acid having an acid dissociation constant (pKa) smaller than the constant of acetic acid is allowed to be present in the reaction system, acetic acid can be produced by the reaction of methanol and carbon monoxide in a reaction liquid in the presence of a solid catalyst containing rhodium and alkyl iodide, to achieve an enhanced reaction rate of carbonylation of methanol in producing acetic acid in the region at a high carbonylation degree (Ca>0.8 mol/mol) for more efficient production of acetic acid.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: August 12, 2014
    Assignee: Chiyoda Corporation
    Inventors: Zhixiong You, Takeshi Minami, Chunji Yin, Yoichi Umehara, Tetsuro Matsumura, Chikako Hashimoto, Yasuo Hosono
  • Patent number: 8785155
    Abstract: A method is presented for the production of cellulosic ethanol, acetic acid and derivatives from the extract containing fibers and hemicelluloses after steam cooking of biomass in a host plant. The process is integrated with the host plant process to minimize the effect of loss of heat value from the extracted hemicelluloses and eliminate the need for the waste water treatment plant.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: July 22, 2014
    Assignee: API Intellectual Property Holdings, LLC
    Inventors: Theodora Retsina, Vesa Pylkkanen, Kimberly Nelson
  • Patent number: 8785475
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: July 22, 2014
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • Patent number: 8778838
    Abstract: The present invention relates to aqueous concentrate formulations for plant protection comprising: 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide in the form of its anhydrate; N-(phosphonomethyl)glycine in the form of its free acid, in the form of the ammonium salt or a substituted ammonium salt or a mixture thereof; at least two different non-ionic surfactants with at least one of them comprising an ethylene oxide polymer moiety or an ethylene oxide/C3-C4-alkylene oxide block copolymer moiety, and water; wherein the pH-value of the formulation is below 6.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: July 15, 2014
    Assignee: BASF SE
    Inventors: Michael Krapp, Wolfgang Gregori, Sven Adam, Klaus Kolb, Juergen Jakob, Bernd Sievernich, Joerg Steuerwald, Steven Bowe, Joseph Zawierucha, Rex Liebl
  • Patent number: 8753543
    Abstract: The present invention provides a chemically functionalized submicron graphitic fibril having a diameter or thickness less than 1 ?m, wherein the fibril is free of continuous thermal carbon overcoat, free of continuous hollow core, and free of catalyst. The fibril is obtained by splitting a micron-scaled carbon fiber or graphite fiber along the fiber axis direction. These functionalized graphitic fibrils exhibit exceptionally high electrical conductivity, high thermal conductivity, high elastic modulus, high strength and good interfacial bonding with a matrix resin in a composite. The present invention also provides several products that contain submicron graphitic fibrils: (a) paper, thin-film, mat, and web products; (b) rubber or tire products; (c) energy conversion or storage devices, such as fuel cells, lithium-ion batteries, and supercapacitors; (d) adhesives, inks, coatings, paints, lubricants, and grease products; (e) heavy metal ion scavenger; (f) absorbent (e.g.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: June 17, 2014
    Assignee: Nanotek Instruments, Inc.
    Inventors: Aruna Zhamu, Bor Z. Jang
  • Publication number: 20140113811
    Abstract: Provided are methods for storing gases on porous adsorbents, methods for optimizing the storage of gases on porous adsorbents, methods of making porous adsorbents, and methods of gas storage of optimized compositions, as in systems containing porous adsorbents and gas adsorbed on the surface of the porous adsorbent. The disclosed methods and systems feature a constant or increasing isosteric enthalpy of adsorption as a function of uptake of the gas onto the exposed surface of a porous adsorbent. Adsorbents with a porous geometry and surface dimensions suited to a particular adsorbate are exposed to the gas at elevated pressures in the specific regime where n/V (density) is larger than predicted by the ideal gas law by more than several percent.
    Type: Application
    Filed: October 10, 2013
    Publication date: April 24, 2014
    Inventors: Nicholas P. STADIE, Brent T. FULTZ, Channing AHN, Maxwell MURIALDO
  • Patent number: 8703183
    Abstract: The present invention relates to metformin glycinate salt and pharmaceutical compositions thereof for the treatment of diabetes mellitus. The method includes administration of the metformin glycinate salt by various routes selected from oral, intravenous injectable, intramuscular injectable, nasal, intraperitoneal, or sublingual, in order to achieve a reduction in blood glucose levels. The invention further relates to the synthesis of a new 1,1-dimethylbiguanide glycinate salt, called Metformin Glycinate. The resulting salt exhibits advantages over other metformin salts. These advantages are due, in the first place, to the fact that the glycine counterion exhibits hypoglycemic effects by itself. Moreover, the salt exhibits more rapid absorption, reaching higher plasma concentrations than those produced with metformin hydrochloride.
    Type: Grant
    Filed: December 24, 2010
    Date of Patent: April 22, 2014
    Assignee: Laboratorios Silanes S.A. de C.V.
    Inventor: Jose Manuel FranciscoOchoa Lara
  • Patent number: 8703108
    Abstract: Cleansing compositions include a mixture of alkyl ether carboxylic acids and/or salts thereof, each having a structure according to formula (1): R1—O—(CH2CH2O)n—CH2—COOM??(1) where R1 is an alkyl group having 4 to 22 carbon atoms, n is a number of from 0 to 20, and M is a hydrogen atom, alkali metal, alkaline earth metal, ammonium, or organic ammonium. The mixture includes alkyl ether carboxylic acids and/or salts having at least two different alkyl groups R1, an average carbon number of alkyl groups R1 of alkyl ether carboxylic acids and/or salts in the mixture is from 10.8 to 12.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: April 22, 2014
    Assignee: Kao Corporation
    Inventors: Hiroki Takeuchi, Masahiro Miyaki, Naoko Yamamoto, Natsuko Toshida, Jurgen Benade
  • Publication number: 20140087978
    Abstract: A method of converting an inactive biocide into an active biocide comprises: contacting the inactive biocide with an activating agent, wherein the activating agent is capable of chemically reacting with the inactive biocide; and causing or allowing a chemical reaction to take place between the inactive biocide and the activating agent, wherein the chemical reaction produces the active biocide. The methods can also include deactivating the active biocide via a chemical reaction between the active biocide and a deactivating agent.
    Type: Application
    Filed: September 27, 2012
    Publication date: March 27, 2014
    Applicant: HALLIBURTON ENERGY SERVICES, INC
    Inventor: Jay P. DEVILLE
  • Publication number: 20140031584
    Abstract: The present invention relates to methods for safe and efficient use of hydrogen and oxygen in ozonolysis operations. The invention also relates to an ozonolysis process involving elements of both reductive and oxidative ozonolysis which are integrated in a continuous process. In one embodiment, the ozonolysis process of the present invention uses hydrogen and/or oxygen generated from water and electricity, which may be recycled to generate water and/or electricity.
    Type: Application
    Filed: July 19, 2013
    Publication date: January 30, 2014
    Inventors: Patrick Foley, Yonghua Yang
  • Patent number: 8591938
    Abstract: The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: November 26, 2013
    Assignee: Lyne Laboratories, Inc.
    Inventor: Stephen C. Tarallo
  • Patent number: 8592480
    Abstract: The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: November 26, 2013
    Assignee: Lyne Laboratories, Inc.
    Inventor: Stephen C. Tarallo
  • Patent number: 8575389
    Abstract: The invention relates to a continuous neutralization process in which at least one ethylenically unsaturated carboxylic acid is neutralized at least partly with a base and the temperature of the neutralized solution is less than 70° C., and also to an apparatus for carrying out the process.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: November 5, 2013
    Assignee: BASF SE
    Inventors: Matthias Weismantel, Michael de Marco, Dominicus van Esbroeck, Karl J. Possemiers, Ronny De Kaey
  • Patent number: 8519185
    Abstract: Glycolic acid having a high purity is obtained by subjecting glycolic acid or a glycolic acid solution containing contaminants to double-chamber electrodialysis combined with one or more treatments selected from among treatment with an activated carbon, treatment with an ion exchange resin, concentration treatment and cooling crystallization.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: August 27, 2013
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Shinya Okazaki, Kaori Matoishi, Kiyoshi Itou
  • Publication number: 20130196155
    Abstract: A method for surface treating a carbon-containing material in which carbon-containing material is reacted with decomposing ozone in a reactor (e.g., a hollow tube reactor), wherein a concentration of ozone is maintained throughout the reactor by appropriate selection of at least processing temperature, gas stream flow rate, reactor dimensions, ozone concentration entering the reactor, and position of one or more ozone inlets (ports) in the reactor, wherein the method produces a surface-oxidized carbon or carbon-containing material, preferably having a surface atomic oxygen content of at least 15%. The resulting surface-oxidized carbon material and solid composites made therefrom are also described.
    Type: Application
    Filed: February 1, 2012
    Publication date: August 1, 2013
    Applicant: UT-Battelle, LLC
    Inventors: Felix Leonard Paulauskas, Soydan Ozcan, Amit K. Naskar
  • Patent number: 8481784
    Abstract: In one aspect, a process for the preparation of a superabsorbent polymer is described herein. In some embodiments, the process comprises (I) preparing acrylic acid, wherein the process comprises (a1) provision of a fluid F1 having a composition comprising from about 5 to about 20 wt. % of hydroxypropionic acid, salts thereof, or mixtures thereof; from about 0.1 to about 5 wt. % of inorganic salts; from about 0.1 to about 30 wt. % of organic compounds which differ from hydroxypropionic acid; from 0 to about 50 wt. % of solids; and from about 20 to about 90 wt. % of water; (a2) dehydration of said hydroxypropionic acid to give a fluid F2 containing acrylic acid; and (a3) purification of said fluid F2 to give a purified acrylic acid phase comprising acrylic acid having a purity of at least 70 wt. %; and (II) polymerizing the acrylic acid of (I) to form a superabsorbent polymer.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: July 9, 2013
    Assignee: Evonik Degussa GmbH
    Inventors: Franz-Felix Kuppinger, Axel Hengstermann, Guido Stochniol, Gunther Bub, Jurgen Mosler, Andreas Sabbagh
  • Patent number: 8450369
    Abstract: The present invention is directed to novel diacid derivatives, pharmaceutical compositions comprising the diacid derivatives and methods for the treatment of insulin and non-insulin dependent diabetes mellitus and related disorders comprising administering to a subject in need thereof, the compounds of the present invention.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: May 28, 2013
    Assignee: CIP Kemicals, Corp.
    Inventor: Roberto Iglesias Lores
  • Publication number: 20130130985
    Abstract: Peptide analogues of oxytocin are described together with methods of treating conditions ameliorated by modulating oxytocin receptor. The peptide analogues are seleno or telluro peptide analogues. Methods of synthesis of selenocysteine, tellurocysteine and oxytocin analogues are also described.
    Type: Application
    Filed: May 24, 2010
    Publication date: May 23, 2013
    Inventors: Paul Alewood, Markus Muttenthaler, Zoltan Dekan
  • Publication number: 20130130318
    Abstract: A method is presented for the production of cellulosic ethanol, acetic acid and derivatives from the extract containing fibers and hemicelluloses after steam cooking of biomass in a host plant. The process is integrated with the host plant process to minimize the effect of loss of heat value from the extracted hemicelluloses and eliminate the need for the waste water treatment plant.
    Type: Application
    Filed: May 15, 2012
    Publication date: May 23, 2013
    Applicant: API INTELLECTUAL PROPERTY HOLDINGS, LLC
    Inventors: Theodora RETSINA, Vesa PYLKKANEN, Kimberly NELSON
  • Publication number: 20130091759
    Abstract: A method of production of value-added, biobased chemicals, derivative products, and/or purified glycerin from plant-based bioglycerin is described herein. A method of purification of plant-based bioglycerin is also described herein. The method of purification of plant-based bioglycerin described provides methods for desalinating, decolorizing, and/or concentrating plant-based bioglycerin for the production of biobased chemicals, derivative products, and/or purified glycerin.
    Type: Application
    Filed: January 12, 2012
    Publication date: April 18, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Christopher M. Yost
  • Publication number: 20130096326
    Abstract: A method of purification and production of value-added, biobased chemicals and derivative products from crude bioglycerin is described herein. The present method provides methods for desalinating, decolorizing, and concentrating bioglycerin for the production of biobased chemicals or purified bioglycerin.
    Type: Application
    Filed: October 12, 2011
    Publication date: April 18, 2013
    Applicant: THESIS CHEMISTRY, LLC
    Inventors: John R. Peterson, Christopher M. Yost
  • Publication number: 20130089790
    Abstract: A self-supporting carbon electrode can include, or consist essentially of, nanostructured carbon, for example, oxygen-functionalized nanostructured carbon.
    Type: Application
    Filed: October 11, 2011
    Publication date: April 11, 2013
    Inventors: Hye Ryung Byon, Seung Woo Lee, Betar Gallant, Yang Shao-Horn, Paula Hammond, Nasim Hyder
  • Publication number: 20130078704
    Abstract: Methods of processing chemicals change their structure, and in particular increase their solubility and/or rate of dissolution, for intermediates and products made from the structurally changed materials. Many of the methods provide materials that can be more readily utilized in reactions or other processes to produce useful intermediates and products, e.g., energy, fuels, foods or materials. Chemicals that are treated using the processes described herein can be used to form highly concentrated solutions. Treatment can change the functionality of the chemical, and thus the polarity of the chemical, which may render the treated chemical soluble in solvents in which the untreated chemical is insoluble or only sparingly or partially soluble. Methods may in some cases increase the solubility of the chemical in water or aqueous media. The chemical may be, for example, a solid, liquid, or gel, or mixtures thereof.
    Type: Application
    Filed: November 20, 2012
    Publication date: March 28, 2013
    Applicant: Xyleco, Inc.
    Inventor: Xyleco, Inc.
  • Patent number: 8367864
    Abstract: The present invention relates to soluble dimeric double metal salt compositions of (?)-hydroxycitric acid (“HCA”), as well as methods for making and using the same. The invention provides dimeric double metal salts of group IA and IIA of HCA (hereinafter, “DDM-HCAs”). The present invention provides methods to make DDM-HCAs of the invention which can be employed to alter the polar/ionic qualities of HCA salts and derivatives to improve solubility of HCA compositions. DDM-HCAs of the invention are soluble HCA-containing compositions useful as dietary supplements and suitable for manipulations under those conditions necessary for tabletting, encapsulation, and the production of dry powders, particularly for use as a beverage premix. Methods of use of the composition include treatment for suppression of appetite, for weight loss, for an increase in the rate of fat metabolism, for reduction in blood lipids and postprandial lipemia, and to increase the plasma level of (?)-hydroxycitric acid.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: February 5, 2013
    Assignee: Glykon Technologies Group, LLC
    Inventors: Alex Moffett, Parag Shah
  • Patent number: 8324428
    Abstract: The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the synthesis of these compounds libraries thereof. The synthesis of these novel stabilized compounds involves (1) synthesizing a peptide from a selected number of natural or non-natural amino acids, wherein said peptide comprises at least two moieties capable of undergoing reaction to promote carbon-carbon bond formation; and (2) contacting said peptide with a reagent to generate at least one crosslinker and to effect stabilization of a secondary structure motif. The present invention, in a preferred embodiment, provides stabilized p53 donor helical peptides. Additionally, the present invention provides methods for disrupting the p53/MDM2 binding interaction comprising (1) providing a crosslinked stabilized ?-helical structure; and (2) contacting said crosslinked stabilized ?-helical structure with MDM2.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: December 4, 2012
    Assignee: President and Fellows of Harvard College
    Inventors: Gregory L. Verdine, Christian E. Schafmeister