Plural Benzene Rings Bonded Directly To The Same Nitrogen Patents (Class 562/61)
  • Patent number: 6218571
    Abstract: 8-(anilino)-1-naphthalenesulfonate (ANS) analogs and methods for their use in analyte detection assays are provided. The subject ANS analogs are characterized by having at least one non-hydrogen substituent on their phenyl moiety and producing a reaction product with 3-methyl-2-benzothiazolinone hydrazone hydrchloride (MBTH) or an analog thereof, e.g. MBTHSB, that exhibits reduced drift. In certain preferred embodiments, the subject ANS analogs are described by the formula: wherein: n is 1 to 5; and X is a substituent other than H. The subject ANS analogs find use in a variety of applications, particularly in analyte detection assays, such as glucose detection assays.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: April 17, 2001
    Assignee: LifeScan, Inc.
    Inventors: Xiaoling Zheng, Yeung Siu Yu, Adva Yani, Paing C. Huang
  • Patent number: 5599933
    Abstract: The reaction product of:(a) a compound of the formula: ##STR1## wherein X is a member selected from the group consisting of N, O and S; R.sub.1 and R.sub.2 are independently a straight or branched, saturated or unsaturated non-aromatic hydrocarbon of four to eighteen carbon atoms; m is 1 or 2; and n is 0, 1 or 2; and(b) a compound selected from the group consisting of primary, secondary, tertiary and higher amines, which are liquid at room temperature.The reaction product of the present invention has excellent surfactant properties, and is suitable for use in coloring compositions to improve the fugitivity from skin and clothing. The reaction product is also useful as a cleansing agent.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: February 4, 1997
    Assignee: Binney & Smith Inc.
    Inventor: Richard J. Kaiser
  • Patent number: 4992589
    Abstract: Compounds of the formula (1) ##STR1## in which X denotes a sulfur atom or the group ##STR2## in which R denotes a hydrogen atom, an alkylene-C.sub.1 -C.sub.4 -alkoxy-C.sub.1 -C.sub.6 - or alkyl-C.sub.1 -C.sub.6 - group, each of which can be substituted by hydroxyl, sulfo, carboxyl or cyano groups, R.sub.1 denotes a hydrogen atom or an alkyl-C.sub.1 -C.sub.6 -group which can be substituted by --SO.sub.3 M or COOM groups (where M denotes an H, Li, Na, K or Ca atom), hydroxyl, amino, methylamino, acetylamino, alkyl-C.sub.1 -C.sub.4 -sulfonylamino, methoxy, ethoxy, .beta.-hydroxyethylsulfonyl, phenyl, monosulfophenyl, disulfophenyl, or 4-[.beta.-hydroxyethylsulfonyl]-2-sulfophenyl groups, or represents a phenyl or naphthyl group, each of which can be substituted by --SO.sub.3 M or COOM groups (where M denotes an H, Li, Na, K or Ca atom), alkyl-C.sub.1 -C.sub.4 -, alkoxy-C.sub.1 -C.sub.4 -, amino, methylamino, alkyl-C.sub.1 -C.sub.4 -sulfonylamino or acetylamino groups, and R.sub.
    Type: Grant
    Filed: August 10, 1988
    Date of Patent: February 12, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hermann Fuchs, Theodor Papenfuhs, Werner Brodt, Folker Kohlhaas
  • Patent number: 4968835
    Abstract: Aminoaryl-sulphonic acids can be prepared by reaction of arylamines and sulphuric acid at elevated temperature and under pressure, where water formed and, where appropriate, water present as water of dilution, is left in the reaction mixture until the end of the reaction.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: November 6, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinz U. Blank, Herbert Emde, Peter Schnegg
  • Patent number: 4948919
    Abstract: A process for the preparation of arylaminonitrophenyl hydroxyethyl sulfones of the formula (1) ##STR1## in which Z denotes the radical ##STR2## in which R.sub.1 denotes a hydrogen atom or an --NH.sub.2, --NH--R or --N(R).sub.2 group, R representing a C.sub.1 -C.sub.4 -alkyl group, R.sub.2 denotes a hydrogen atom, a C.sub.1 -C.sub.4 -alkyl group or a C.sub.1 -C.sub.4 -alkoxy group, R.sub.3 represents a hydrogen, chlorine or bromine atom or a sulfonic acid, sulfonamide, carboxylic acid, carboxamide, hydroxyl, carbomethoxy, carboethoxy or hydroxyethylsulfonyl group, R.sub.4 denotes a hydrogen, chlorine or bromine atom or a sulfonic acid, carboxylic acid, hydroxy or C.sub.1 -C.sub.4 -alkoxy or C.sub.1 -C.sub.4 -alkyl group, it being possible for 1-3 different R.sub.1 -R.sub.3 substituents, not more than two of which may, however, be identical, to be present in the radical Z.sub.a, and for 1-4 different R.sub.1 -R.sub.
    Type: Grant
    Filed: January 24, 1989
    Date of Patent: August 14, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Brodt, Theodor Papenfuhs
  • Patent number: 4900327
    Abstract: This invention encompasses preparations containing hair dyes of the formula ##STR1## wherein: one of R.sup.1 or R.sup.2 is a nitro and the other is --SO.sub.3 H;one of R.sup.3 or R.sup.4 is --NR.sup.6 R.sup.7 and the other is hydrogen, chlorine, or a C.sub.1-4 alkyl, and R.sup.6 and R.sup.7 are independently hydrogen, C.sub.1-4 alkyl, or C.sub.2-4 hydroxyalkyl; andR.sup.5 is hydrogen, chlorine, or a C.sub.1-4 alkyl;or a water soluble salt thereof; certain novel compounds within the above formula; and a method for dyeing hair.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: February 13, 1990
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: David Rose, Edgar Lieske, Norbert Maak
  • Patent number: 4859206
    Abstract: This invention encompasses compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 independently are hydrogen, C.sub.1-4 alkyl, or C.sub.2-4 hydroxyalkyl; one of R.sup.3 to R.sup.7 is --SO.sub.3 H or --COOH; and the remaining of R.sup.3 to R.sup.7 independently are hydrogen, chlorine, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, or --NR.sup.8 R.sup.9, where R.sup.8 and R.sup.9 independently are hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkoxy, or where --NR.sup.8 R.sup.9 is piperidine, morpholine, piperazine, or pyrrolidone; or a water soluble salt thereof; hair dye preparation containing these compounds, and methods for dyeing hair using such preparation.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: August 22, 1989
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: David Rose, Edgar Lieske, Horst Hoeffkes, Norbert Maak