Boron Containing Patents (Class 568/1)
  • Patent number: 9469604
    Abstract: Provided is a sulfonium salt manufacturing method which can reduce the production of a monosulfonium salt. A method of manufacturing a sulfonium salt includes preparing a first sulfonium salt containing a sulfonium cation and a first anion, preparing a second sulfonium salt by exchanging the first anion for a halide ion, and preparing a third sulfonium salt by exchanging the halide ion for a second anion.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: October 18, 2016
    Assignee: TOYO GOSEI CO., LTD.
    Inventor: Satoshi Enomoto
  • Patent number: 9403849
    Abstract: The present invention relates to the use of aromatic boronic acid or borinic acid derivatives in organic electronic devices, in particular electroluminescent devices.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: August 2, 2016
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Esther Breuning, Arne Buesing, Amir Hossain Parham, Holger Heil, Horst Vestweber
  • Patent number: 9309268
    Abstract: A borate moiety-contained linker and a bio-sensing element containing the same are disclosed. The borate moiety-contained linker can be used to modify a sensing molecule and connect the sensing molecule to a substrate to form the bio-sensing element.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: April 12, 2016
    Assignee: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Yaw-Kuen Li, Mo-Yuan Shen, Yu-Ju Pien
  • Patent number: 9113629
    Abstract: Provided herein are 4-amino-6-(4-substituted-phenyl)-picolinic acids and their derivatives, and 6-amino-2-(4-substituted-phenyl)-pyrimidine-4-carboxylic acids and their derivatives, compositions comprising the acids and their derivatives, and methods of use thereof as herbicides.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 25, 2015
    Assignee: Dow AgroSciences LLC
    Inventors: Joseph D. Eckelbarger, Jeffrey B. Epp, Lindsey G. Fischer, Natalie C. Giampietro, Nicholas M. Irvine, Jeremy Kister, William C. Lo, Christian T. Lowe, Jeffrey Petkus, Joshua Roth, Norbert M. Satchivi, Paul R. Schmitzer, Thomas L. Siddall, Carla N. Yerkes
  • Patent number: 8962572
    Abstract: A bortezomib composition includes bortezomib and boric acid in a mass ratio of boric acid to bortezomib is from 1:1 to 10:1. The composition is a solid, and may be prepared by forming a liquid mixture including a solvent, bortezomib and boric acid, and lyophilizing the liquid mixture.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: February 24, 2015
    Assignee: Fresenius Kabi USA, LLC
    Inventors: Arunya Usayapant, David Bowman
  • Patent number: 8933273
    Abstract: A borate moiety-contained linker and a bio-sensing element containing the same are disclosed. The borate moiety-contained linker can be used to modify a sensing molecule and connect the sensing molecule to a substrate to form the bio-sensing element.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: January 13, 2015
    Assignee: National Chiao Tung University
    Inventors: Yaw-Kuen Li, Mo-Yuan Shen, Yu-Ju Pien
  • Patent number: 8877980
    Abstract: The present invention relates to a specific phenylboronic acid compound having anti-cancer, anti-inflammatory, and anti-microbial activity, in addition to a pharmaceutical composition comprising the same. The present invention also discloses a process for preparing said compound.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: November 4, 2014
    Assignee: Al-Urdonia Lemudaddat Al-Ajsam Co.
    Inventors: Khaled Mahmood Al-Qaoud, Penelope Ahmad Shihab, Luay Fawzi Abu-Qatouseh, Christopher R. Lowe, Abdel Monem Mohammad Rawashdeh, Yusuf Abdalsalam Alkhayyat, Samer Sami Ratrout, Saleem Muneer Naser
  • Patent number: 8865942
    Abstract: A method for producing high-purity 2-cyanophenylboronic acid, characterized by reacting benzonitrile, lithium 2,2,6,6-tetramethylpiperidide, and trialkoxyborane, adding an aqueous acidic solution to a reaction solution containing the obtained 2-cyanophenylboronic acid, carrying out a contact treatment at a pH of below 7 in the presence of a water-immiscible organic solvent, and then obtaining the 2-cyanophenylboronic acid from the organic layer.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: October 21, 2014
    Assignee: Tosoh Finechem Corporation
    Inventor: Shinichiro Nakamura
  • Patent number: 8822730
    Abstract: Provided herein are methods of isolating a 4-chloro-2-fluoro-3-substituted-phenylboronic acid. The method comprises contacting a mixture of water, a water-miscible organic solvent, and a 4-chloro-2-fluoro-3-substituted-phenylboronic acid with a salt to form a water-miscible organic solvent layer and a water layer. The 4-chloro-2-fluoro-3-substituted-phenylboronic acid is partitioned into the water-miscible organic solvent layer, which is separated from the water layer. Additional methods are disclosed, as is a 4-chloro-2-fluoro-3-substituted-phenylboronic acid produced by one of the methods, wherein the 4-chloro-2-fluoro-3-substituted-phenylboronic acid is obtained at a yield of greater than approximately 90%.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: September 2, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventor: Jossian Oppenheimer
  • Publication number: 20140205951
    Abstract: A thermal crosslinking accelerator of a polysiloxane compound is shown by the following general formula (A-1), wherein R11, R12, R13, and R14 each represents a hydrogen atom, a halogen atom, a linear, a branched, a cyclic alkyl group having 1 to 20 carbon atoms, an optionally substituted aryl group having 6 to 20 carbon atoms, or an aralkyl group having 7 to 20 carbon atoms, wherein some or all of the hydrogen atoms in these groups may be substituted by an alkoxy group. “a”, “b”, “c”, and “d” represent an integer of 0 to 5; in the case that “a”, “b”, “c”, and “d” are 2 or more, R11, R12, R13, and R14 may form a cyclic structure.
    Type: Application
    Filed: December 27, 2013
    Publication date: July 24, 2014
    Applicant: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Tsutomu OGIHARA, Yusuke BIYAJIMA, Hiroyuki URANO
  • Patent number: 8702815
    Abstract: The present invention relates to dyes of the general formula CAT+ Y? (I), where Y? is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT+ is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for coloring plastics and plastic fibers, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for coloring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: April 22, 2014
    Assignee: Merck Patent GmbH
    Inventors: Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Helge Willner, Maik Finze, Eduard Bernhardt, Andriy Kucheryna
  • Patent number: 8674141
    Abstract: The present invention relates to the use of aromatic boronic acid or borinic acid derivatives in organic electronic devices, in particular electroluminescent devices.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: March 18, 2014
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Esther Breuning, Arne Buesing, Amir Hossain Parham, Holger Heil, Horst Vestweber
  • Publication number: 20140045779
    Abstract: This invention relates with anti-tumor activities of new compounds containing an adamantyl group or analogs thereof.
    Type: Application
    Filed: August 29, 2011
    Publication date: February 13, 2014
    Inventor: Lifeng Xu
  • Patent number: 8586203
    Abstract: Novel organic compounds comprising ligands containing a boron-nitrogen heterocycle are provided. In particular, the compound is a metal complex comprising a ligand containing an azaborine. The compounds may be used in organic light emitting devices to provide devices having improved photophysical and electronic properties.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: November 19, 2013
    Assignee: Universal Display Corporation
    Inventors: Raymond Kwong, Bin Ma, Jui-Yi Tsai, Scott Beers, Ed Barron, Gregg Kottas, Alexey Borisovich Dyatkin
  • Publication number: 20130184461
    Abstract: Mechanosynthesis trajectories are described which are approximately coaxial, and are shown to be useful in a wide range of mechanosynthesis reactions regardless of the nature of the tip or the feedstock being transferred.
    Type: Application
    Filed: February 28, 2013
    Publication date: July 18, 2013
    Inventors: Robert A. Freitas, JR., Ralph C. Merkle
  • Publication number: 20130178626
    Abstract: Processes are described for manufacturing atomically-precise tips using one or more tips in one or more mechanosynthetic reactions to create one or more atomically-precise tips. The processes may employ a variety of feedstock, binding any of a wide range of atoms to a workpiece to build the one or more atomically-precise tips. The processes result in atomically-precise mechanosynthesis tips with a wide variety of possible tip structures using a wide range of feedstock binding elements. Characteristics of such tips that may be used when designing new embodiments are also described.
    Type: Application
    Filed: February 28, 2013
    Publication date: July 11, 2013
    Inventors: Robert A. Freitas, JR., Ralph C. Merkle
  • Publication number: 20130178627
    Abstract: Methods and systems for building three-dimensional workpieces are described using a plurality of mechanosynthetic reactions. These methods may employ engineered reliability in reactions and process conditions and may use simulated or otherwise vetted reaction sequences, to allow workpieces requiring many reactions to be built with acceptable reliability. These many reactions may be the repetition of one or a small number of reactions, or many diverse reactions, or a combination thereof.
    Type: Application
    Filed: February 28, 2013
    Publication date: July 11, 2013
    Inventors: Robert A. Freitas, JR., Ralph C. Merkle
  • Patent number: 8436199
    Abstract: The invention relates to boron-containing acids of the general formula (I) [B(RF)4-x-y(CN)xFy]?H+ (I), where x=0, 1, 2, 3 or 4, y=0, 1, 2 or 3 x+y?4, and in which the ligands RF may be identical or different and RF stands for a perfluorinated or partially fluorinated C1-12-alkyl group and where the CN group is bonded to the B atom via the C atom, and complexes thereof with a solvent, to salts comprising a cation and the anion of a selection of the acids according to the invention, and to processes for the preparation of the salts.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: May 7, 2013
    Assignee: Merck Patent GmbH
    Inventors: Maik Finze, Eduard Bernhardt, Helge Willner, Nikolai (Mykola) Ignatyev, Urs Welz-Biermann
  • Patent number: 8420755
    Abstract: The present invention relates to a novel metallocene compound, a catalyst composition including the compound and an olefin polymer prepared using the same. The metallocene compound and the catalyst composition can be used for preparing the olefin polymer with high copolymerization degree and high molecular weight. Particularly, the block copolymer with high heat resistance can be prepared by using the metallocene compound, and the olefin polymer with high melting point (Tm) can be obtained, even if co-monomer is used at an increased amount in preparation of olefin polymer.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: April 16, 2013
    Assignee: LG Chem, Ltd.
    Inventors: Young-Chul Won, Sung-Ho Chun, Dai-Seung Choi, Dong-Woo Yoo, Bun-Yeoul Lee
  • Publication number: 20130059996
    Abstract: The synthesis, functionalization and characterization of borepin-based extended pi-electron molecules is disclosed. Bulky substituents shielded the vacant boron p-orbitals thus allowing synthetic manipulation and purification under ambient lab conditions. The presently disclosed borepin-containing compounds displayed reversible cathodic electrochemistry and can be viewed as n-type analogues to bent acene hydrocarbons.
    Type: Application
    Filed: April 8, 2011
    Publication date: March 7, 2013
    Inventors: John Dayton Tovar, Anthony Caruso, JR.
  • Patent number: 8383862
    Abstract: Provided are a salt compound, cationic polymerization initiator and cationically polymerizable composition, which have a superior acid-generating capacity and high sensitivity, and are free from coloration. The salt compound is represented by the following general Formula (1): (wherein, R01 to R05 each independently represents a group selected from a hydrogen atom, a fluorine atom and —YR group, one of the R01 to R05 being a —YR group and at least two of the R01 to R05 being fluorine atoms; Y represents an oxygen atom or a sulfur atom; R represents a C1-C4 alkyl group; Ctp+ represents a p-valent cation, the p being 1 or 2; and n represents a coefficient required for maintaining electrical neutrality).
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: February 26, 2013
    Assignee: Adeka Corporation
    Inventors: Kentaro Kimura, Shohei Fujita, Tomoya Tamachi
  • Patent number: 8283497
    Abstract: The present invention relates to novel tricyanoborates of the general formula Catn+[B(CN)3(XR1)]—n, wherein R1 is C1-6 alkyl, C2-6 alkenyl, C6-10 aryl or benzyl; X is oxygen or sulfur; and Catn+ is a cation with n being 1 or 2, which is selected from the group consisting of an inorganic cation and an organic cation; and also their preparation and use.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: October 9, 2012
    Assignee: Lonza Ltd.
    Inventors: Wolfgang Wenger, Cornelia Zur Taschler
  • Patent number: 8278456
    Abstract: The present invention is directed to the synthesis and stabilization of neutral molecules containing homonuclear single or multiple bonds, methods of preparation, and uses thereof.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 2, 2012
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Gregory H. Robinson, Yuzhong Wang
  • Patent number: 8263810
    Abstract: The invention provides methods for storing boranes (e.g. B-allyldiisopinocampheylborane). The invention also provides stable compositions comprising boranes, as well as methods for carrying out allylboration at high temperature and/or in the presence of water.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: September 11, 2012
    Assignees: Regents of the University of Minnesota, Sigma-Aldrich Co. LLC
    Inventors: Venkatram R. MeReddy, Kanth V. B. Josyula
  • Patent number: 8258346
    Abstract: Provided is a composition comprising hexagonal boron nitride particles having a surface and a substituted phenyl radical bonded to the surface, the substituted phenyl radical being represented by the structure: where X is a radical selected from NH2—, HO—, R2OC(O)—, R2C(O)O—, HSO3—, NH2CO—, halogens, alkyl or aryl, including substituted aryl; where R1 is hydrogen, alkyl or alkoxy, and R2 is hydrogen, alkyl or aryl, including substituted aryl. A process for preparing the composition is also provided.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: September 4, 2012
    Assignee: E I du Pont de Nemours and Company
    Inventor: Govindasamy Paramasivam Rajendran
  • Patent number: 8222457
    Abstract: A coordination compound of an element of the boron group, the production of the compound and methods of using the compound as an additive, stabilizer, catalyst, co-catalyst, activator for catalyst systems, conductivity improver, and electrolyte.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: July 17, 2012
    Assignee: Chemetall GmbH
    Inventors: Wolfram Lerner, Jens Röder, Hannes Vitze, Matthias Wagner, Ulrich Wietelmann
  • Patent number: 8207337
    Abstract: [Problem] To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. [Means for Solving Problems] The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R1 represents alkyl, alkenyl, etc.; R2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m+ represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).
    Type: Grant
    Filed: January 28, 2008
    Date of Patent: June 26, 2012
    Assignee: Wako Pure Chemical Industries, Ltd.
    Inventors: Norio Miyaura, Yasunori Yamamoto
  • Patent number: 8148443
    Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?xHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1, 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFWRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: April 3, 2012
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
  • Patent number: 8097463
    Abstract: Tagging of Histidine in polypeptides with arylboronic acid tagging reagents for identifying proteins in a sample by isolating and identifying Histidine-comprising peptides from one protein sample or a pool of protein samples. Databases of Histidine-including peptides from in silico cleaved proteins are uses in the identification of proteins.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: January 17, 2012
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Ralf Hoffmann, Helga Hummel, Volker Weiler
  • Publication number: 20110269629
    Abstract: Partially or fully saturated doped graphene materials are found to be superconducting. The saturation is with hydrogen or halogen. Doping is performed by substitution of carbon atoms or by applying an electric field. Diamond nano-rods are also found to be superconducting. These materials can be used in electronic devices having a gate.
    Type: Application
    Filed: February 2, 2011
    Publication date: November 3, 2011
    Applicant: ISIS INNOVATION LIMITED
    Inventors: Feliciano Giustino, Andrea C. Ferrari, Gianluca Savini
  • Publication number: 20110230678
    Abstract: Disclosed is an organic framework including: planar layers formed by successively connecting building blocks arranged in the vicinity of each other, in which each of the building blocks includes two or three C6 to C204 aromatic ring groups covalently bonded to a linear or annular boron-containing cluster; and a Lewis base coordinated to the boron-containing cluster within the planar layers.
    Type: Application
    Filed: November 17, 2009
    Publication date: September 22, 2011
    Applicant: INSILICOTECH CO., LTD
    Inventors: Dong Hyun Jung, Minkyoung Kim, Daejin Kim, Seung-Hoon Choi, Jihye Yoon, Sang Beom CHoi, Eunhee Jo, Jaheon Kim
  • Publication number: 20110207934
    Abstract: The present invention relates to new borane complexes with substituted pyridines, a process for the synthesis of new borane complexes with substituted pyridines, solutions comprising new borane complexes with substituted pyridines and a method of using new borane complexes with substituted pyridines for organic reactions.
    Type: Application
    Filed: September 20, 2007
    Publication date: August 25, 2011
    Applicant: BASF SE
    Inventor: Elizabeth Burkhardt
  • Patent number: 7887920
    Abstract: A borate for a near-infrared ray absorption material, having an anion represented by the formula (1): [BR1mR24-m]? (wherein R1 represents an aryl group having an electron withdrawing group; R2 represents an organic group, a halogen group or a hydroxyl group; and m is an integer in the range of 1 to 4) is provided. The borate of the present invention enables to improve durability, in particular, heat resistance and moisture resistance of a near-infrared ray absorbing dye.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: February 15, 2011
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Akio Ito, Satoshi Ishida, Toshiya Iida, Takako Ishii, Nobuhiro Kobayashi
  • Patent number: 7879461
    Abstract: An excellent composition for a charge-transport film, which can be used to produce an organic electroluminescence device having excellent heat-resistant property, high hole injection/transport capacity and capable of functioning at a low voltage, is proposed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: February 1, 2011
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Koichiro Iida, Tomoyuki Ogata, Asato Tanaka
  • Patent number: 7858827
    Abstract: The invention relates to a process for the synthesis of dialkoxyorganoboranes, in particular to a process for the synthesis of dialkoxyorganoboranes by an ester exchange reaction. Moreover, the invention relates to a process for the synthesis of organo-oxazaborolidine catalysts (organo-CBS) and of trialkylboroxins. Furthermore, the invention relates to methods of using dialkoxyorganoboranes for the preparation of organo-CBS catalysts and in Suzuki-type coupling reactions.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: December 28, 2010
    Assignee: BASF SE
    Inventors: Elizabeth Burkhardt, William Atkins
  • Patent number: 7838697
    Abstract: A manufacturing method for one of, or a mixture of, an optically active allylboron compound and racemic or optically active boryl cyclopropane, including a coupling reaction, in the presence of a catalyst, between allyl compound and diboron compound. It is preferred that a copper (I) complex is used as the catalyst. It is preferred that a counterion of the copper (I) complex is an alkoxide or a hydride. It is preferred that the copper (I) complex has a phosphine ligand. It is preferred that the phosphine ligand is a chiral phosphine ligand.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: November 23, 2010
    Assignee: Nippon Chemical Industrial Co., Ltd.
    Inventors: Masaya Sawamura, Hajime Ito
  • Publication number: 20100276674
    Abstract: An organic light-emitting device comprising an anode; a hole transport layer; a light-emitting layer; and a cathode, characterised in that the hole transport layer comprises a polymer having a repeat unit comprising a 9,9 biphenyl fluorene unit wherein the 9-phenyl rings are independently and optionally substituted and the fluorene unit is optionally fused.
    Type: Application
    Filed: November 18, 2008
    Publication date: November 4, 2010
    Applicants: CAMBRIDGE DISPLAY TECHNOLOGY LIMITED, SUMATION CO., LIMITED
    Inventors: Natasha M. Conway, Mary J. McKiernan, Brian Tierney
  • Publication number: 20100163852
    Abstract: The present invention provides a light emitting device material which enables a light emitting device having high efficiency and excellent chromatic purity and durability using a light emitting device material containing a pyrene compound represented by formula (1), wherein any one of R1 to R10 is a group represented by formula (2), or 1 to 4 substituents is/are group(s) represented by formula (3), and a light emitting device using the same.
    Type: Application
    Filed: June 8, 2007
    Publication date: July 1, 2010
    Inventors: Kazumasa Nagao, Seiichiro Murase
  • Patent number: 7732215
    Abstract: The present invention relates to a cyanide detection method using fluorescence and cyanide sensitive boronic acid containing fluorophores, wherein a change in a measured fluorescent property correlates to the concentration of the cyanide compound in a biological or environmental test sample.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: June 8, 2010
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Chris D. Geddes, Ramachandram Badugu, Joseph R. Lakowicz
  • Patent number: 7704752
    Abstract: Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is a non-polymeric organic group, B is a boron atom, and each R is independently selected from hydrogen, alkyl and aryl groups and can be joined together as a straight or branched alkylene chain forming a ring or as an aromatic ring. A detectable product compound of the formula Sig-OH or Sig-O? is produced and detected by measuring color, absorbance, fluorescence, chemiluminescence, or bioluminescence. The signalling compound itself does not possess the detectable property or does so only to a very weak degree. The methods can be used as a detectable signal in assays for peroxide or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: April 27, 2010
    Assignee: Lumigen, Inc.
    Inventors: Hashem Akhavan-Tafti, Robert A. Eickholt, Kenneth S. Lauwers, Richard S. Handley
  • Publication number: 20100071769
    Abstract: Disclosed is a novel fluorene derivative and an organic electronic device using the same. The organic electronic device has excellent efficiency, driving voltage, and a lifespan.
    Type: Application
    Filed: December 6, 2007
    Publication date: March 25, 2010
    Inventors: Jae-Soon Bae, Dong-Hoon Lee, Dae-Woong Lee, Sung-Ku Hong, Hyun Nam, Chang-Hwan Kim
  • Patent number: 7683229
    Abstract: The present invention relates to novel truxene and isotruxene derivatives, in particular spirotruxene and spiroisotruxene derivatives, and to the use thereof in organic electronic devices, in particular organic electroluminescent devices.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: March 23, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Esther Breuning, Liliana Bagala′ Rampazzo, Giulia Fioravanti, Leonardo Mattiello
  • Publication number: 20100029875
    Abstract: A coordination compound of an element of the boron group, the production of the compound and methods of using the compound as an additive, stabilizer, catalyst, co-catalyst, activator for catalyst systems, conductivity improver, and electrolyte.
    Type: Application
    Filed: November 19, 2007
    Publication date: February 4, 2010
    Inventors: Jens Röder, Ulrich Wietelmann, Matthias Wagner, Wolfram Lerner, Hannes Vitze
  • Publication number: 20100010265
    Abstract: Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity.
    Type: Application
    Filed: September 21, 2009
    Publication date: January 14, 2010
    Inventors: Alexander Christian Comely, Marta Marfil Sanchez, Llorenc Rafecas Jane, Xavier Verdaguer Espaulella
  • Patent number: 7635595
    Abstract: The spectroscopic and photophysical properties of fluorescent probes comprising donor-acceptor derivatives comprising the boric acid group or a derivative of boric acid, B(OH)3 (or borate ion, BO(OH)2?1), arsenious acid, H3 AsO3 (or arsenite ion, H2AsO3?1), telluric acid, H6TeO6 (or tellurate ion, H5 TeO6?1) or germanic acid, Ge(OH)6 (or germanate ion, GeO(OH)3?1) are described. Method of using said probes are also provided.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: December 22, 2009
    Inventors: Joseph R. Lakowicz, Nicolas Dicesare
  • Patent number: 7622613
    Abstract: The present invention relates to a thiol compound represented by formula (1): wherein R1, R2 and n have the same meanings as in the specification, method for producing the compound, and to a photosensitive composition and a black matrix resist composition using the same which have high sensitivity and excellent property of retaining a line width in fine line patterns at the time of alkaline development, that is, being excellent in development latitude.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: November 24, 2009
    Assignee: Showa Denko K.K.
    Inventors: Hirotoshi Kamata, Mina Onishi, Katsumi Murofushi
  • Patent number: 7598302
    Abstract: The present invention is directed to an adhesion promoter for bonding fluoropolymers and, more specifically, for bonding a fluoroplastic layer to a fluroelastomer layer in a multi-layered article, such as a fuel filler hose. In one embodiment, the adhesion promoter includes a solvent, a polyallyamine (PAA), and an organo-onium compound. The solvent can include an organic solvent, such as an alcohol, e.g., methanol, ethanol, or isopropanol. The polyallylamine includes a homopolymer of 2-propen-1-amine, and the organo-onium compound can include an organic phosphonium salt. The final composition of the adhesion promoter can include solvent in the range of about 80% by weight to about 99% by weight; polyallylamine in the range of about 0.5% by weight to about 10% by weight; and organo-onium compound in the range of about 0.5% by weight to about 10% by weight. Such adhesion promoter may further optionally include a silane, such as an organosilane.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: October 6, 2009
    Assignee: Veyance Technologies, Inc
    Inventor: Ramon Joseph DiMascio
  • Patent number: 7589239
    Abstract: The present invention is directed to novel compounds according to formula (I) wherein R1, R2, and X are as defined herein. The invention also discloses methods of preparation, pharmaceutical compositions, and methods of disease treatment utilizing pharmaceutical compositions comprising these compounds. The compounds of this invention are novel therapeutic agents for the treatment of cancer, diabetes, metabolic diseases and skin disorders in mammalian subjects. These compounds are also useful modulators of gene expression. They exert their activity by interfering with certain cellular signal transduction cascades. The compounds of the invention are thus also useful for regulating cell differentiation and cell cycle processes that are controlled or regulated by various hormones or cytokines. The invention also discloses pharmaceutical compositions and methods of treatment of disease in mammals.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: September 15, 2009
    Assignee: Auspex Pharmaceuticals
    Inventor: Sepehr Sarshar
  • Publication number: 20090184289
    Abstract: A method for producing high-purity 2-cyanophenylboronic acid, characterized by reacting benzonitrile, lithium 2,2,6,6-tetramethylpiperidide, and trialkoxyborane, adding an aqueous acidic solution to a reaction solution containing the obtained 2-cyanophenylboronic acid, carrying out a contact treatment at a pH of below 7 in the presence of a water-immiscible organic solvent, and then obtaining the 2-cyanophenylboronic acid from the organic layer.
    Type: Application
    Filed: April 11, 2007
    Publication date: July 23, 2009
    Inventor: Shinichiro Nakamura
  • Publication number: 20090134384
    Abstract: The present invention relates to the use of aromatic boronic acid or borinic acid derivatives in organic electronic devices, in particular electroluminescent devices.
    Type: Application
    Filed: April 6, 2006
    Publication date: May 28, 2009
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Esther Breuning, Arne Buesing, Amir Hossain Parham, Holger Heil, Horst Vestweber