Sulfur Or Oxygen Containing Patents (Class 568/11)
  • Patent number: 10494390
    Abstract: An organic magnesium phosphide expressed by Formula (1) below and an organic magnesium phosphide complex expressed by Formula (9) below are provided, and a manufacturing method of organic phosphorus compound is characterized in that the above compounds used as a reagent is reacted with an electrophile: wherein R1 and R2 are each independently an aliphatic group, heteroaliphatic group, alicyclic group, or heterocyclic group, and X is chlorine, bromine, or iodine, wherein R3 and R4 are each independently an aliphatic group, heteroaliphatic group, aromatic group, alicyclic group, or heterocyclic group, and X and Y are each independently chlorine, bromine, or iodine.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: December 3, 2019
    Assignee: HOKKO CHEMICAL INDUSTRY CO., LTD.
    Inventors: Kenta Suzuki, Nobumichi Kumamoto, Nobuhiro Ito, Shinji Hatae, Hiroyuki Suzuki
  • Patent number: 9006491
    Abstract: The current invention relates to the structure, synthesis of dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate, as well as its applications in the palladium catalyzed carbon-chlorine bond activation for Suzuki coupling reactions and carbon-nitrogen bond formation reactions. The dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate could coordinate with the palladium catalyst to activate the inert carbon-chlorine bond highly selectively and catalyze Suzuki coupling reaction with arylboronic acid or carbon-nitrogen bond formation reaction with organic amines. The current invention uses only one step to synthesize dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate is stable in the air. Compared with known synthetic routes of ligands used in activating carbon-chlorine bonds, the method of current invention is short, easy to operate.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: April 14, 2015
    Assignee: Zhejiang University
    Inventors: Shengming Ma, Bo Lü, Chunling Fu
  • Publication number: 20150087863
    Abstract: Provided is a catalyst composition suitable for curing a fluoroelastomer, the catalyst composition comprising an anion of Formula III: wherein each Rf independently is selected from R—CF2 and a perfluoroalkyl group having from 1 to 8 carbon atoms. R is selected from H, a halogen, an alkyl group having up to 8 carbon atoms, an aryl group having up to 8 carbon atoms, and a cycloalkyl group having up to 8 carbon atoms. The subscript n is a positive integer. The catalyst composition is free of hydrocarbon containing alcohol. In specific instances, Rf may be CF3.
    Type: Application
    Filed: December 5, 2014
    Publication date: March 26, 2015
    Inventors: Werner M.A. Grootaert, Kim M. Vogel, Dennis E. Vogel
  • Patent number: 8962600
    Abstract: Apocynin derivative compounds, active pharmaceutical ingredients, dosage forms, and methods of use thereof as neuroprotectants in the brain of mammals.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: February 24, 2015
    Assignee: The Medical College of Wisconsin, Inc.
    Inventors: Balaraman Kalyanaraman, Joy Joseph, Anumantha Kanthasamy
  • Patent number: 8957243
    Abstract: The present invention provides phosphonium ionic liquids (11) and coatings made therefrom. Highly fluorinated phosphonium ionic liquids based on (11) having been produced exhibiting high thermal stabilities, low melting points and temperature dependent solvent miscibilities. These salts and derivatives of (11) have also been employed in the preparation of superhydrophobic surfaces, indicating that ionic liquids are not only new alternative solvents, but also viable functional materials. All derivatives of (11) form biphasic systems with common laboratory solvents of ranging polarity at room temperature. Based on the solvent miscibility experiments with water and the high fluorine loading, the PILs showed obvious evidence of being hydrophobic. Coatings made with these phosphonium ionic liquids (11), salts and derivatives thereof were superhydrophobic with water contact angles were measured and all of the surfaces were determined to be superhydrophobic with contact angles >150°.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: February 17, 2015
    Assignee: The University of Western Ontario
    Inventors: Paul J. Ragogna, Jocelyn J. Tindale
  • Patent number: 8952199
    Abstract: The present invention provides methods and formulations for reducing or inhibiting increase in the concentration of microbes in a water-based fluid. The methods and formulations of the present invention use glutaraldehyde and a hydroxymethyl-substituted phosphorus compound selected from the group consisting of tetrakis(hydroxymethyl)phosphonium salts, C1-C3 alkyl- and alkenyltris(hydroxymethyl)phosphonium salts and tris(hydroxymethyl)phosphine, in a ratio of hydroxymethyl-substituted phosphorus compound to glutaraldehyde in the range of about 2:1 to about 7:1, or about 3.5:1 to about 7.5:1. The methods and formulations of the present invention can be useful in treating water contaminated with aerobic or anaerobic bacteria in oilfield and other industrial applications.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: February 10, 2015
    Assignee: Dow Global Technologies LLC
    Inventors: Bei Yin, Jingjun Yang
  • Patent number: 8846978
    Abstract: In some embodiments, the inventions described herein relate to a composition of matter comprising a molecule having the structure: wherein: independently at each occurrence, R1 is a halogen, a alkyl group, a heteroalkyl group, an aryl group, or a heteroaryl group; R2 comprises from 3 to 30 CH2— groups, n=0-5, m=0-5, q=1-3, and R2 comprises at least one ether linkage.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: September 30, 2014
    Assignees: Imperial Innovations Ltd., Georgia Tech Research Corporation
    Inventors: Peter Hotchkiss, Seth Marder, Anthony Giordano, Thomas D. Anthopoulos
  • Patent number: 8772549
    Abstract: Disclosed is a method for making a diphosphite of Structure I,
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: July 8, 2014
    Assignee: INVISTA North America S.à r.l.
    Inventors: Joachim C. Ritter, Thomas E. Vos
  • Patent number: 8703902
    Abstract: Polymerizable ionic liquid monomers and their corresponding polymers (poly(ionic liquid)s) are created and found to exhibit high absorption of radio frequency electromagnetic radiation, particularly in the microwave and radar bands. These materials are useful for coating objects to make them less reflective of radio frequency radiation and for making objects that absorb radio frequency radiation and are of minimal reflectivity to radio frequency radiation. Free-radical and condensation polymerization approaches are used in the preparation of the poly(ionic liquids).
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: April 22, 2014
    Assignee: University of Wyoming
    Inventors: Maciej Radosz, Youqing Shen, Huadong Tang
  • Patent number: 8647780
    Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, 0, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FXI0)N—(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.
    Type: Grant
    Filed: March 7, 2011
    Date of Patent: February 11, 2014
    Assignee: Acep Inc.
    Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
  • Patent number: 8609901
    Abstract: Disclosed is a method for making a diphosphite of Structure I,
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: December 17, 2013
    Assignee: Invista North America S.A R.L.
    Inventors: Joachim C. Ritter, Thomas E. Vos
  • Publication number: 20130116473
    Abstract: The present invention relates to the preparation of oxovinylionol and its O-protected derivatives of the formula I in which R is hydrogen or an OH protecting group, for example a group Si(Ra)3, by reacting a compound of the general formula II in which R has the meanings given above for formula I, i.e. ?-vinyl ionol (formula II, R=hydrogen) or an O-protected derivative thereof (formula II, R?OH protecting group) with an oxidant in the presence of at least one transition metal, where the oxidant comprises at least one oxygen-containing compound which is selected from among hydrogen peroxide and organic hydroperoxides.
    Type: Application
    Filed: November 9, 2012
    Publication date: May 9, 2013
    Applicant: BASF SE
    Inventor: BASF SE
  • Patent number: 8436057
    Abstract: An anion exchange membrane and fuel cell incorporating the anion exchange membrane are detailed in which proazaphosphatrane and azaphosphatrane cations are covalently bonded to a sulfonated fluoropolymer support along with anionic counterions. A positive charge is dispersed in the aforementioned cations which are buried in the support to reduce the cation-anion interactions and increase the mobility of hydroxide ions, for example, across the membrane. The anion exchange membrane has the ability to operate at high temperatures and in highly alkaline environments with high conductivity and low resistance.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: May 7, 2013
    Assignee: U.S. Department of Energy
    Inventors: John G. Verkade, Kuldeep Wadhwa, Xueqian Kong, Klaus Schmidt-Rohr
  • Patent number: 8436055
    Abstract: The present invention provides an ion-exchange resin catalyst, as a catalyst for preparing bisphenol from phenol compounds and ketone, which has a higher selectivity to bisphenol and a longer life time, as compared to a conventional ion-exchange resin, and a method for preparing the same. The present invention also provides a method for preparing bisphenol comprising reacting phenol compounds with ketone, wherein the modified acidic ion-exchange resin in which at least one kind of cationic compound selected from the following (a), (b), (c) and (d) ionically binds to an acidic functional group, is used as a catalyst: (a) a quaternary phosphonium ion, (b) a quaternary ammonium ion, (c) a bis(phosphoranylidene) ammonium ion, and (d) an N-substituted nitrogen-containing aromatic cation.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: May 7, 2013
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Takashi Terajima, Toshihiro Takai, Kenji Fujiwara
  • Patent number: 8426479
    Abstract: There is provided a modified ion exchange resin catalyst which exhibits higher bisphenols selectivity than the conventional modified ion exchange resins in processes wherein bisphenols are produced by reacting a phenolic compound with ketones, and to provide such a process for producing bisphenols.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: April 23, 2013
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Takashi Terajima, Toshihiro Takai, Hideaki Nakamura
  • Patent number: 8404758
    Abstract: The invention provides methods for inducing reversible chain cleavage of polymer chains in a crosslinked polymeric material. Reversible cleavage of the polymer backbone is capable of relieving stress in the polymeric material as the bonds reform in a less stressed state. The invention also provides methods for making polymeric materials capable of reversible chain cleavage, materials made by the methods of the invention, and linear monomers containing reversible chain cleavage groups which are useful in the materials and methods of the invention.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: March 26, 2013
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Christopher N. Bowman, Timothy F. Scott
  • Publication number: 20130037753
    Abstract: Disclosed is an organic electronic material comprising charge transporting compounds and ionic compounds having electron-accepting properties and high solubility in a solvent. The organic electronic material is characterized by comprising charge transporting compounds and ionic compounds, and in that at least one of the ionic compounds is any one kind of compounds represented by general formulas (1b)-(3b). (In the formulas Y1-Y6 each independently represent a divalent linking group, R1-R6 each independently represent an electron-attracting organic substituent (these structures can further have substituents and hetero-atoms, and R1, R2 and R3, or, R4-R6 can respectively combine and become a ring shape or a polymer shape) and L+ represents a monovalent cation.
    Type: Application
    Filed: April 20, 2011
    Publication date: February 14, 2013
    Applicant: HITACHI CHEMICAL COMPANY, LTD
    Inventors: Kenichi Ishitsuka, Shigeaki Funyuu, Yousuke Hoshi
  • Publication number: 20120065321
    Abstract: A catalyst composition comprising a cation and an anion of the formula Anq?Qpm+, wherein m, n, p, and q are positive integers, wherein m*p=n*q, wherein Qm+ is an organo onium, and Aq? is an anion, provided that at least one Aq? is selected from the formula (I) wherein each R independently is H, halo, alkyl, aryl, aralkyl, or cycloalkyl, and which also may be halogenated, fluorinated, or perfluorinated, wherein two or more of R and R? groups may together form a ring, wherein each R group independently may contain one or more heteroatom(s), wherein R? can be the same as R, with the proviso that R? cannot be halo, and wherein the catalyst composition is essentially free of hydrocarbon containing alcohol.
    Type: Application
    Filed: June 24, 2010
    Publication date: March 15, 2012
    Inventors: Werner M.A. Grootaert, Kim M. Vogel, Dennis E. Vogel
  • Patent number: 8129568
    Abstract: A composition comprising a compound of formula (I) or (II): wherein r and q are independently integers of 1 to 3; Rf is linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; j is an integer 0 or 1, or a mixture thereof, x is 1 or 2, Z is —O— or —S—, X is hydrogen or M, and M is an ammonium ion, an alkali metal ion, or an alkanolammonium ion is disclosed.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: March 6, 2012
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Sheng Peng, Stephen James Getty, Xianjun Meng
  • Patent number: 8049040
    Abstract: Fluorophosphate containing an ethylene-tetrafluoroethylene moiety of formula (I) or (II): (A)w-P(O)(O?M+)3-w??(I) or wherein A is Rf—(CH2)k—[(CF2CF2)y—(CH2CH2)z]mO and contains from about 8 to about 22 carbon atoms; Rf is CnF2n+1; n and k are each independently 1 to about 6; y, z, and m are each independently 1, 2, 3, or mixture thereof; w is 1 or 2 or a mixture thereof; and M is hydrogen, ammonium ion, an alkali metal ion, or an alkanolammonium ion, said fluorophosphate useful as a surfactant for altering the surface behavior of a liquid by addition thereto, and for providing surface effects to a substrate treated with a composition containing the fluorophosphate.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: November 1, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Weiming Qiu, Xiuling Shirley Wang
  • Publication number: 20110245207
    Abstract: The invention relates to biology and medicine, in particular, can be used in medicine for preparation of a pharmaceutical composition for specific, self-regulating uncoupling of mitochondria. The invention may be useful in treatment of diseases and conditions associated with violation of cellular metabolism, in treatment of obesity including its pathological forms, as well as in treatment of diseases associated with increased formation of free radicals and reactive oxygen species. In addition, the invention may be used in biotechnology for stimulation of growth of yeast and microorganisms as well as for stimulation of development of tissues and organs of plant and animal origin.
    Type: Application
    Filed: November 12, 2008
    Publication date: October 6, 2011
    Applicant: MITOTECH SA
    Inventors: Maxim V. Skulachev, Vladimir P. Skulachev
  • Publication number: 20110224461
    Abstract: There is provided a modified ion exchange resin catalyst which exhibits higher bisphenols selectivity than the conventional modified ion exchange resins in processes wherein bisphenols are produced by reacting a phenolic compound with ketones, and to provide such a process for producing bisphenols.
    Type: Application
    Filed: May 19, 2011
    Publication date: September 15, 2011
    Inventors: Takashi TERAJIMA, Toshihiro Takai, Hideaki Nakamura
  • Patent number: 7999111
    Abstract: The invention relates to a process for the preparation of onium alkylsulfonates by reaction of an onium halide or carboxylate with a symmetrically substituted dialkyl sulfite or with an asymmetrically substituted dialkyl sulfite at temperatures of 50 to 170° C.
    Type: Grant
    Filed: June 14, 2006
    Date of Patent: August 16, 2011
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Andriy Kucheryna, Helge Willner
  • Publication number: 20110160487
    Abstract: ITQ-40 (INSTITUTO DE TECNOLOGÍA QUÍMICA number 40) is a new crystalline microporous material with a framework of tetrahedral atoms connected by atoms capable of bridging the tetrahedral atoms, the tetrahedral atom framework being defined by the interconnections between the tetrahedrally coordinated atoms in its framework. ITQ-40 can be prepared in silicate compositions with an organic structure directing agent. It has a unique X-ray diffraction pattern, which identifies it as a new material.
    Type: Application
    Filed: December 15, 2010
    Publication date: June 30, 2011
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Karl G. Strohmaier, Avelino Corma, Maria Jose Diaz, Fernando Rey, Douglas L. Dorset, Stuart L. Soled
  • Patent number: 7968612
    Abstract: There is provided a modified ion exchange resin catalyst which exhibits higher bisphenols selectivity than the conventional modified ion exchange resins in processes wherein bisphenols are produced by reacting a phenolic compound with ketones, and to provide such a process for producing bisphenols.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: June 28, 2011
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Takashi Terajima, Toshihiro Takai, Hideaki Nakamura
  • Patent number: 7951975
    Abstract: A composition comprising a compound of formula (I) or (II): wherein r and q are independently integers of 1 to 3; Rf is linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; j is an integer 0 or 1, or a mixture thereof, x is 1 or 2, Z is —O— or —S—, X is hydrogen or M, and M is an ammonium ion, an alkali metal ion, or an alkanolammonium ion is disclosed.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: May 31, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Sheng Peng, Stephen James Getty, Xianjun Meng
  • Publication number: 20110124900
    Abstract: A method for preparing substantially pure optionally substituted diaryl alkylphosphonates from an optionally substituted triarylphosphite and an optionally substituted trialkylphosphite or an optionally substituted alkanol under special reaction conditions is described.
    Type: Application
    Filed: February 1, 2011
    Publication date: May 26, 2011
    Applicant: FRX POLYMERS, INC.
    Inventors: Dieter FREITAG, Savvas Hadjikyriacou
  • Publication number: 20110092683
    Abstract: There are provided compounds of formulas (VA), (VIA), (VIIA) (IXA), (XIA), (XIIA), (XIIIA), and (XIVA): wherein A, Z, R2, X?, and L2 represent various different possibilities. Methods for using such compounds are also provided.
    Type: Application
    Filed: December 21, 2010
    Publication date: April 21, 2011
    Applicant: VALORISATION-RECHERCHE, LIMITED PARTNERSHIP
    Inventors: André Charette, Jean-Christophe Poupon, Alessandro Boezio
  • Patent number: 7901812
    Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N?(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: March 8, 2011
    Assignees: ACEP Inc., Centre National de la Recherche Scientifique, Universite de Montreal
    Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
  • Publication number: 20110053895
    Abstract: The invention relates to pharmacology and medicine, in particular to a class of mitochondrially-addressed compounds which can be used in the pharmaceutical compositions of medicinal agents (preparations) for preventing and treating cardiovascular diseases and diseases and pathological conditions caused by disturbed blood circulation or oxygen supply to tissues and organs.
    Type: Application
    Filed: June 29, 2007
    Publication date: March 3, 2011
    Inventors: Maxim Vladimirovich Skulachev, Vladimir Petrovich Skulachev
  • Patent number: 7888335
    Abstract: This invention relates to pharmaceutically acceptable amphiphilic antioxidant compounds, compositions and dosage forms comprising said compounds, and methods and uses reliant on said compounds. The exemplified compounds are all mitoquinone derivatives, being methoxyphenyl alkyl triphenylphosphonium or methoxy dioxocyclohexadiene alkyl triphenylphosphonium derivatives. The compounds, compositions, dosage forms, uses and methods are useful in, for example, the treatment of diseases or conditions associated with oxidative stress.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: February 15, 2011
    Assignee: Antipodean Pharmaceuticals, Inc.
    Inventors: Kenneth Martin Taylor, Robin A. J. Smith
  • Publication number: 20100323992
    Abstract: The present invention relates to pharmacology, medicine, opthalmology, and, in particular, concerns a class of chemical compounds of structure (I) and also their solvates, isomers or prodrugs applicable when incorporated into pharmaceutical compositions also containing pharmaceutically acceptable carrier which can be useful for prophylaxis and treatment of different eye pathologies such as cataract and macular dystrophy.
    Type: Application
    Filed: October 20, 2006
    Publication date: December 23, 2010
    Inventors: Vladimir P. Skulachev, Maxim V. Skulachev
  • Patent number: 7838706
    Abstract: The invention disclosed a total synthesis process of novel ethoxy combretastatins and their prodrugs. Combretastatins are chemically modified by ethoxy substituted on the 4?-position of their B aryl ring and are converted to be their soluble prodrugs of phosphate or their inner salt of phosphorylcholine by modifying the hydroxyl on the 3?-position of their B aryl ring. Similarly, 3?-amino combretastatin is 4?-ethoxy chemically modified and further side chain of amino acid can be introduced to the amino to form soluble prodrug of amino acidamide. The structure of the said compound is showed as formula (I). Ethoxy combretastatins possess potent tubulin polymerization inhibitory activity and can be used for the treatment of inhibiting tumor or neovascular.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: November 23, 2010
    Assignee: Zhejiang Dade Pharmaceutical Group Co. Ltd
    Inventors: Weiping Shen, Jianping Wang, Jianguo Wang
  • Publication number: 20100240615
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: March 26, 2010
    Publication date: September 23, 2010
    Applicants: University of Orago, Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • Publication number: 20100215578
    Abstract: One aspect of the present invention relates to a method of preparing radiofluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, potassium fluoride-18 is used. Another aspect of the invention relates to piperazine compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the piperazine compounds contain a quaternary amine. Another aspect of the invention relates to arylphosphonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the phosphonium compound is a tetraaryl phosphonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a compound of the invention, and acquiring a positron emission spectrum of the mammal.
    Type: Application
    Filed: December 15, 2009
    Publication date: August 26, 2010
    Applicant: The General Hospital Corporation
    Inventors: David R. Elmaleh, Alan J. Fischman, Timothy M. Shoup
  • Publication number: 20100197969
    Abstract: The object of the present invention is the use of phosphonium salts in coupling reactions, and a method for their preparation.
    Type: Application
    Filed: July 25, 2008
    Publication date: August 5, 2010
    Applicant: DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK
    Inventors: Klemenz Kromm, Jan Haller
  • Patent number: 7732546
    Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain hydrophilic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. The polymeric compositions comprise polymerizable hydrophilic siloxanyl monomers.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 8, 2010
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph C. Salamone, Jay F. Kunzler
  • Patent number: 7592489
    Abstract: A composition comprising a mixture, having a maximum molar ratio of acid to base of 0.6 and providing water repellency when applied to a substrate surface without etching of said surface, of A) an anionic aqueous fluoroalkyl phosphate solution which provides at least about 75% of the total fluorine content of said composition, and B) a cationic copolymer of fluoroalkyl(meth)acrylate or perfluoroalkylether(meth)acrylate present at a minimum of 0.3 g per 100 g of said composition.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: September 22, 2009
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Chandra Tier Miller, Andrea Miller-Simmons, legal representative, Faye Michelle Corman, Ernest Byron Wysong
  • Publication number: 20090233873
    Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.
    Type: Application
    Filed: March 27, 2009
    Publication date: September 17, 2009
    Applicants: University of Otago, Medical Research Council
    Inventors: Robin Andrew James Smith, Michael Patrick Murphy
  • Publication number: 20090198082
    Abstract: The present invention is to provide a process for producing dicyanonorbornane characterized by causing hydrogen cyanide to undergo addition reaction with cyanonorbornene (bicyclo[2.2.1]-5-heptene-2-carbonitrile) in the presence of a zerovalent nickel complex catalyst which is produced by using a phosphite represented by P(x)(y)(z) (wherein P is a phosphorus atom, and x, y and z are each OR, where R represents an aryl group having not more than 18 carbon atoms) as a ligand to reduce a nickel halide with at least one metal selected among zinc, cadmium, beryllium, aluminum, iron and cobalt, wherein the phosphite is one which has a phosphate content of 1.0 weight % or lower based on the whole phosphite.
    Type: Application
    Filed: June 22, 2007
    Publication date: August 6, 2009
    Applicant: MITSUI CHEMICALS , INC.
    Inventors: Norihiko Fukatsu, Hiroyuki Morijiri, Chitoshi Shimakawa, Koichi Tokunaga, Seiichi Kobayashi
  • Publication number: 20090099381
    Abstract: The present invention relates to a production method capable of producing an optically active ?-hydroxyphosphonic acid and its derivatives with sufficiently high enantioselectivity not only for aromatic aldehydes but also for aliphatic aldehydes, and more specifically to a method of producing an optically active ?-hydroxyphosphonic acid and its derivatives, characterized in that an optically active aluminum(salalen) complex represented by any one of the following formulae (I), (I?), (II) and (II?): [wherein R1s are each alkyl group or aryl group independently; R2s are each alkyl group or aryl group independently; R3s are each alkyl group or aryl group independently, and two R3s may bond with each other to form a ring; R4s are each hydrogen atom, halogen atom, alkyl group, alkoxy group, nitro group, or cyano group independently; R5 is alkyl group; and X1 is halogen atom, alkyl group, alkoxy group, acetoxy group or toluenesulfonyloxy group] is used as a catalyst to asymmetrically hydrophosphonylate an aldeh
    Type: Application
    Filed: March 20, 2006
    Publication date: April 16, 2009
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Tsutomu Katsuki, Bunnai Saito
  • Publication number: 20090088517
    Abstract: A curative composition comprising a cation and an anion of the formula Anq?Qpm+, wherein m, n, p, and q are positive integers, wherein m*p=n*q, wherein Qm+ is an organo onium, and Aq? is an anion, provided that at least one Aq? is selected from the formula: wherein each R independently is H, halo, alkyl, aryl, aralkyl, or cycloalkyl, and which also may be halogenated, fluorinated, or perfluorinated, wherein two or more of R and R? groups may together form a ring, wherein each R group independently may contain one or more heteroatom(s), wherein R? can be the same as R, with the proviso that R? cannot be halo. Also provided are a fluoropolymer composition including this curative, a method of making a fluoropolymer, and fluoropolymer articles containing curable or cured fluoropolymer compositions.
    Type: Application
    Filed: June 13, 2008
    Publication date: April 2, 2009
    Inventors: Werner M.A. Grootaert, Eric W. Adair, Miguel A. Guerra
  • Patent number: 7488818
    Abstract: The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the preparation of 1,4-diphenylazetidinone derivatives from ?-substituted amino amides which are protected in the presence of silylating agents and at least one cyclization catalyst whose structural formula is represented by one of the general formula: wherein the various R-groups are defined herein.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: February 10, 2009
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Andreas Lindenschmidt, David William Will, Gerhard Jaehne, Theodor Andreas Wollmann, Wendelin Frick, Bernd Junker, David Rigal, Guenter Billen, Heiner Jendralla
  • Publication number: 20090036628
    Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?zHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1 , 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFwRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.
    Type: Application
    Filed: January 5, 2007
    Publication date: February 5, 2009
    Inventors: Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
  • Patent number: 7470818
    Abstract: A composition comprising a compound of formula (I) or (II): wherein r and q are independently integers of 1 to 3; Rf is linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; j is an integer 0 or 1, or a mixture thereof, x is 1 or 2, Z is —O— or —S—, X is hydrogen or M, and M is an ammonium ion, an alkali metal ion, or an alkanolammonium ion is disclosed.
    Type: Grant
    Filed: November 13, 2006
    Date of Patent: December 30, 2008
    Assignee: E.I. Du Pont De Nemours & Company
    Inventors: Sheng Peng, Stephen James Getty, Xianjun Meng
  • Publication number: 20080269526
    Abstract: Disclosed are methods for making the phosphonium sulfonate salt of generic formula (1): wherein each X is independently a halogen or hydrogen, provided that the molar ratio of halogen to hydrogen is greater than about 0.90; p is 0 or 1 and q and r are integers of 0 to about 7 provided that q+r is less than 8 and that if p is 1 then r is greater than zero; and each R is the same or different hydrocarbon radical containing 1 to about 18 carbon atoms, the method comprising the steps of combining in an aqueous medium, a compound of the generic formula (2): wherein M is K, and X, q, p, and r are as defined above, with a compound of the generic formula (3): (R)4P-Z ??(3) wherein Z is a halogen and R is as defined above; and separating the phosphonium sulfonate of formula (1) from the aqueous medium. Also disclosed is an antistatic composition comprising phosphonium sulfonate (1), and articles prepared therefrom.
    Type: Application
    Filed: July 9, 2008
    Publication date: October 30, 2008
    Applicant: SAIC INNOVATIVE PLASTICS, IP B.V.
    Inventors: Theodorus Lambertus Hoeks, Chiel Albertus Leenders, Robert Dirk van de Grampel
  • Publication number: 20080221334
    Abstract: The invention relates to a process for the preparation of onium alkylsulfonates by reaction of an onium halide or carboxylate with a symmetrically substituted dialkyl sulfite or with an asymmetrically substituted dialkyl sulfite at temperatures of 50 to 170° C.
    Type: Application
    Filed: June 14, 2006
    Publication date: September 11, 2008
    Inventors: Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Andriy Kucheryna, Helge Willner
  • Publication number: 20080161267
    Abstract: This invention relates to pharmaceutically acceptable amphiphilic antioxidant compounds, compositions and dosage forms comprising said compounds, and methods and uses reliant on said compounds. The exemplified compounds are all mitoquinone derivatives, being methoxyphenyl alkyl triphenylphosphonium or methoxy dioxocyclohexadiene alkyl triphenylphosphonium derivatives. The compounds, compositions, dosage forms, uses and methods are useful in, for example, the treatment of diseases or conditions associated with oxidative stress.
    Type: Application
    Filed: August 23, 2004
    Publication date: July 3, 2008
    Applicant: Antipodean Pharmaceuticals, Inc.
    Inventors: Kenneth Martin Taylor, Robin A.J. Smith
  • Patent number: 7378194
    Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N?(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: May 27, 2008
    Assignees: ACEP, Inc., Centre de la Recherche Scientifique, Universite de Montreal
    Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
  • Patent number: 7342124
    Abstract: Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: March 11, 2008
    Assignees: The Trustees Of The University Of Pennsylvania, Kosan Biosciences, Inc.
    Inventors: David C. Myles, Mark Burlingame, Simon James Shaw, Kurt F. Sundermann, Brian Scott Freeze, Ignació Brouard Martin, Tomoyasu Hirose, Amos B. Smith, III