Phosphorus Containing Patents (Class 568/8)
  • Patent number: 10081649
    Abstract: A transition metal amino borohydride material includes a first row transition metal in conjunction with an amine ligand and borohydride, in a condition of having been thermally treated to a temperature of at least 70° C. and up to but not including 800° C. An exemplary such material, Fe(DETA)(BH4)2 having been heat treated at 300° C., had good hydrogen storage characteristics.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: September 25, 2018
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Albert Epshteyn, Zachary J. Huba, William Maza
  • Patent number: 9416109
    Abstract: The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: August 16, 2016
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: George Anthony Moniz, Annie Zhu Wilcoxen, Farid Benayoud, Jaemoon Lee, Huiming Zhang, Taro Terauchi, Ayumi Takemura, Yu Yoshida, Toshiaki Tanaka, Keiichi Sorimachi, Yoshimitsu Naoe, Yuji Kazuta
  • Patent number: 9243011
    Abstract: The present invention relates to the compound of dialkyl(2-alkoxy-6-aminophenyl)phosphine and the preparation method thereof and the application in the palladium catalyzed coupling reactions of aryl chloride and ketone. The dialkyl(2-alkoxy-6-aminophenyl)phosphine of the present invention could coordinate with the palladium catalyst to highly selectively activate the inert carbon-chlorine bond, and to catalyze direct arylation reaction in the ?-position of ketones to produce corresponding coupling compounds. The preparation method of the present invention is a simple one-step method which produces the air-stable dialkyl(2-alkoxy-6-aminophenyl)phosphine. Compared with the synthetic routes of ligands to be used in the activation of carbon-chlorine bonds in the prior arts, the preparation method of the present invention has the advantages of short route and easy operation.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: January 26, 2016
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Shengming Ma, Bo Lv, Chunling Fu
  • Patent number: 9127109
    Abstract: A method for preparing a functionalized polymer, the method comprising: polymerizing conjugated diene monomer, optionally together with comonomer, using a phosphorus-containing organometal initiator.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: September 8, 2015
    Assignee: Bridgestone Corporation
    Inventors: Terrence E Hogan, William L Hergenrother
  • Patent number: 9035016
    Abstract: A polymer composition for solar cell and flexible electronics devices, where the polymer is a p-type conducting polymer. The p-type polymer comprises a benzothiadiazole acceptor and indeno-fluorene donor. Further, a solar cell and flexible electronic device article may be made from the polymer.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: May 19, 2015
    Assignee: Saudi Basic Industries Corporation
    Inventors: Dwight Seferos, Brandon Djukic, Ahmed I. Abdelrahman
  • Patent number: 9006491
    Abstract: The current invention relates to the structure, synthesis of dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate, as well as its applications in the palladium catalyzed carbon-chlorine bond activation for Suzuki coupling reactions and carbon-nitrogen bond formation reactions. The dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine or its tetrafluoroborate could coordinate with the palladium catalyst to activate the inert carbon-chlorine bond highly selectively and catalyze Suzuki coupling reaction with arylboronic acid or carbon-nitrogen bond formation reaction with organic amines. The current invention uses only one step to synthesize dialkyl(2,4,6- or 2,6-alkoxyphenyl)phosphine and its tetrafluoroborate is stable in the air. Compared with known synthetic routes of ligands used in activating carbon-chlorine bonds, the method of current invention is short, easy to operate.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: April 14, 2015
    Assignee: Zhejiang University
    Inventors: Shengming Ma, Bo Lü, Chunling Fu
  • Patent number: 8993547
    Abstract: This invention discloses 3-desoxy-2-methylene-19-nor-vitamin D analogs, and specifically (20S)-3-desoxy-2-methylene-1?,25-dihydroxy-19-nor-vitamin D3 and (20R)-3-desoxy-2-methylene-1?,25-dihydroxy-19-nor-vitamin D3 as well as pharmaceutical uses therefor. These compounds exhibit relatively high binding activity and pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to monocytes thus evidencing use as anti-cancer agents especially for the treatment or prevention of osteosarcoma, leukemia, colon cancer, breast cancer, skin cancer or prostate cancer. These compounds also exhibit relatively high calcemic activity evidencing use in the treatment of bone diseases.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: March 31, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Lori A. Plum, Rafal R. Sicinski, Izabela Sibilska, Margaret Clagett-Dame
  • Patent number: 8969624
    Abstract: The invention is directed to a phosphine compound represented by general formula (1) wherein R? and R? independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R? and R? are joined together to form with the phosphorous atom a carbon-phosphorous monocycle comprising at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. Also claimed is the use of these phosphines as ligands in catalytic reactions and the preparation of these phosphines.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: March 3, 2015
    Assignee: Evonik Degussa GmbH
    Inventors: Herbert Plenio, Christoph Fleckenstein, Renat Kadyrov, Juan Almena, Axel Monsees, Thomas Riermeier
  • Patent number: 8932644
    Abstract: The present disclosure is directed toward a composition and method of treating and preventing infection of pathogenic microorganisms and endopyhtic microorganisms in a plant through the use of phosphite compositions.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: January 13, 2015
    Inventor: Don M. Huber
  • Patent number: 8912124
    Abstract: The invention relates to derivatives of (1-cyanocyclopropyl)phenylphosphinic acid of the formula (I) and to salts thereof, of the formula (II), for enhancing stress tolerance in plants to abiotic stress, preferably to drought stress, especially for enhancing plant growth and/or for increasing plant yield.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: December 16, 2014
    Assignee: Bayer Cropscience AG
    Inventors: Lothar Willms, Hans-Joachim Zeiβ, Marco Busch, Christopher Hugh Rosinger, Ines Heinemann, Isolde Häuser-Hahn, Martin Jeffrey Hills, Pascal Von Koskull-Döring
  • Publication number: 20140275615
    Abstract: Methods of preparing compounds according to Formula (I): and salts thereof as well as their corresponding phosphine intermediates are provided herein, wherein R1 and R2 are different and each of R1 and R2 is independently selected from an organic radical that branches at the alpha carbon and an organic radical that branches at the beta carbon, and each of X and Y is independently O or S, and wherein said compound is a liquid at room temperature.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 18, 2014
    Applicant: Cytec Technology Corp.
    Inventors: Yuehui ZHOU, Jeffrey Charles Henry DYCK, Boban JAKOVLJEVIC, Cyril Christian Henri BOURGET, Allan James ROBERTSON, Donato NUCCIARONE
  • Patent number: 8816113
    Abstract: A novel bidentate catalytic ligand of general formula (I) is described. R represents a hydrocarbyl aromatic structure having at least one aromatic ring to which Q1 and Q2 are each linked, via the respective linking group, if present, on available adjacent atoms of the at least one aromatic ring. The groups X3 and X4 represent radicals joined via tertiary carbon atoms to the respective atom Q1 and the groups X1 and X2 represent radicals joined via primary, or substituted aromatic ring carbon atom(s) to the respective atom Q2. A and B represent an optional lower alkylene linking group. Q1 and Q2 each represent phosphorus, arsenic or antimony. A process for the carbonylation of ethylenically unsaturated compounds comprising reacting the compound with carbon monoxide in the presence of a source of hydroxyl groups, optionally, a source of anions and catalyst system obtainable by combining a metal of Group 8, 9 or 10 or a compound thereof and the bidentate ligand of general formula (I) is also described.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: August 26, 2014
    Assignee: Lucite International UK Limited
    Inventors: Graham Ronald Eastham, Mark Waugh, Paul Pringle, Tamara Fanjul Solares
  • Patent number: 8809487
    Abstract: The present disclosure relates to a process for the synthesis of a conducting polymer comprising a benzothiadiazole acceptor and indeno-fluorene donor of formula [IV].
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: August 19, 2014
    Assignee: Saudi Basic Industries Corporation
    Inventors: Dwight Seferos, Brandon Djukic
  • Patent number: 8795736
    Abstract: The present disclosure is directed toward a composition and method of treating and preventing infection of pathogenic microorganisms and endopyhtic microorganisms in a plant through the use of phosphite compositions.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: August 5, 2014
    Inventor: Don M. Huber
  • Patent number: 8735629
    Abstract: A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: May 27, 2014
    Assignee: Chromafora AB
    Inventors: Gaston Laven, Martin Kullberg
  • Patent number: 8702815
    Abstract: The present invention relates to dyes of the general formula CAT+ Y? (I), where Y? is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT+ is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for coloring plastics and plastic fibers, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for coloring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: April 22, 2014
    Assignee: Merck Patent GmbH
    Inventors: Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Helge Willner, Maik Finze, Eduard Bernhardt, Andriy Kucheryna
  • Patent number: 8674125
    Abstract: A method for the creation of a carbon-carbon (C—C) bond or of a carbon-heteroatom (C-HE) bond includes reacting a compound carrying a leaving group with a nucleophilic compound carrying a carbon atom or a heteroatom (HE) capable of replacing the leaving group, thus creating a C—C or C-HE bond, in which process the reaction is carried out in the presence of an effective amount of a catalytic system comprising at least one copper/butadienylphosphine complex.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: March 18, 2014
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Ecole Nationale Superieure de Chimie de Montpellier, Universite Sidi Mohammed Ben Abdellah
    Inventors: Marc Taillefer, Hamid Kaddouri, Fouad Ouazzani, Armelle Ouali
  • Patent number: 8618328
    Abstract: Disclosed herein are phosphine compounds represented by the general formula (4): and corresponding phosphonium salts represented by the general formula (4a): Also disclosed are processes for the preparation of these phosphines and phosphonium salts as well as their use as ligands in catalytic reactions.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: December 31, 2013
    Assignee: Evonik Degussa GmbH
    Inventors: Herbert Plenio, Christoph Fleckenstein, Renat Kadyrov, Juan Almena, Axel Monsees, Thomas Riermeier
  • Patent number: 8609806
    Abstract: To provide phosphorus-containing epoxy resins and phosphorus-containing epoxy resin compositions having high levels of appearance, yield and economic efficiency and cured products thereof that are used for various applications. A phosphorus-containing phenol compound represented by Formula (3) obtained by reacting a compound represented by Formula (2) with a compound represented by Formula (1), wherein in the peak area (A) of the component represented by Formula (1) on a chromatogram measured under specific conditions by gel permeation chromatography, peak area (B) on the high-molecular-weight side of the component of Formula (1), and total area (C) of peak area (A) and peak area (B), the value obtained by dividing peak area (B) by total area (C) is 8 area % or less, and epoxy resin compositions and cured products comprising the phosphorus-containing phenol compound as an essential ingredient.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: December 17, 2013
    Assignee: Nippon Steel & Sumikin Chemical Co., Ltd.
    Inventors: Tetsuya Nakanishi, Hideyasu Asakage, Seigo Takuwa
  • Publication number: 20130267714
    Abstract: Compounds of the formula (I) in the form of a mixture of predominantly one diastereomer or in the form of pure diastereomers, Z1-Q-P*R0R1??(I), wherein: Z1 is a C-bonded, secondary phosphine group of the formula —P(R)2, wherein R is a hydrocarbon radical or O-atom(s)-containing heterohydrocarbon radical having 1 to 18 carbon atoms and optionally substituted by C1-C6-alkyl, trifluoromethyl, C1-C6-alkoxy, trifluoromethoxy, (C1-C4-alkyl)2-amino, (C6H5)3Si, (C1-C12-alkyl)3Si or halogen; Q is selected from the group consisting of: (i) an optionally substituted achiral aromatic group, wherein the achiral aromatic group is bonded directly to Z1 through a carbon atom of the achiral aromatic group and bonded directly to P*R0R1 through a carbon atom of the achiral aromatic group, and (ii) an optionally substituted C1-C4-alkylene group; P* is a chiral phosphorus atom; R0 is methyl; and R1 is a C-bonded optically enriched or optically pure chiral, mono- or polycyclic, nonaromatic hydrocarbon ring; and prepar
    Type: Application
    Filed: April 26, 2013
    Publication date: October 10, 2013
    Inventors: Benoit PUGIN, Matthias LOTZ, Heidi LANDERT, Adrian WYSS, Raphael AARDOOM, Bjorn GSCHWEND, Andreas PFALTZ, Felix SPINDLER
  • Patent number: 8513463
    Abstract: A process is described for the production of one or more of linear nitriles, amides and formamides which includes reacting a nitrogen containing compound, such as ammonia or NOx, and a synthesis gas over a catalyst at a temperature of between 160° C. and 400° C. and a pressure of between 1 bar and 50 bar. A further process for the production of one or more of linear phosphorous containing compounds is also described, which includes reacting a phosphorous containing compound, such as a phosphine, and a synthesis gas over a catalyst at a temperature of between 160° C. and 400° C. and a pressure of between 1 bar and 50 bar. A supported cobalt, iron, ruthenium or rhodium catalyst or an unsupported (bulk) promoted iron catalyst, modified with a promoter is used. The synthesis gas is a mixture of hydrogen and carbon monoxide, in a ratio from 0.5:1 to 5:1; or a mixture of hydrogen and carbon dioxide; or a mixture of water and carbon monoxide.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: August 20, 2013
    Assignees: The University of Cape Town, Carl Von Ossietzky Universitat Oldenburg
    Inventors: Michael Christian Maximilian Claeys, Eric Wilhelmus Josephus Van Steen, Frank Roessner, Tawanda Stephen Sango
  • Publication number: 20130204010
    Abstract: One embodiment of the present invention relates to ionic liquids and ionic viscoelastics formed between [1] a small molecule or macromolecule containing two or more cations; and [2] a small molecule or macromolecule containing two or more anions. Another embodiment of the invention is the use of the inventive ionic liquids and ionic viscoelastics, formed between a small molecule or macromolecule containing two or more cations and a small molecule or macromolecule containing two or more anions, to form a crosslinked network. In certain embodiments, the ionic liquids formed can be viscous liquids, viscous liquid formed networks, or viscoelastic networks/gels. In certain embodiments, the ionic material of the invention may be used for a variety of applications including, but not limited to, lubricants, additives, gas separation, liquid separation, membranes, fuel cells, sensors, batteries, coatings, heat storage, liquid crystals, biocompatible fluids, solvents, and electronic materials.
    Type: Application
    Filed: February 5, 2013
    Publication date: August 8, 2013
    Applicant: Trustees of Boston University
    Inventor: Trustees of Boston University
  • Patent number: 8426647
    Abstract: A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: April 23, 2013
    Assignee: Chromafora AB
    Inventors: Gaston Laven, Martin Kullberg
  • Patent number: 8420755
    Abstract: The present invention relates to a novel metallocene compound, a catalyst composition including the compound and an olefin polymer prepared using the same. The metallocene compound and the catalyst composition can be used for preparing the olefin polymer with high copolymerization degree and high molecular weight. Particularly, the block copolymer with high heat resistance can be prepared by using the metallocene compound, and the olefin polymer with high melting point (Tm) can be obtained, even if co-monomer is used at an increased amount in preparation of olefin polymer.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: April 16, 2013
    Assignee: LG Chem, Ltd.
    Inventors: Young-Chul Won, Sung-Ho Chun, Dai-Seung Choi, Dong-Woo Yoo, Bun-Yeoul Lee
  • Patent number: 8420865
    Abstract: The invention provides a novel peroxide scavenger comprising a phosphine compound represented by general formula [I]: wherein Z1 and Z2 each represents a cyclic group; Ar represents an arylene group; R represents an aliphatic hydrocarbon group; Y represents phosphorus (P), nitrogen (N), or bismuth (Bi); and R1, R2, and R3 each represents a cyclic group, particularly a peroxide scavenger that can scavenge peroxides such as reactive oxygen species which are generated in mitochondria upon exposure to oxidative stress and localized in mitochondria. The phosphine compound of the invention is oxidized by the peroxides localized in mitochondria to increase the fluorescence intensity, whereby the peroxides can be scavenged.
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: April 16, 2013
    Assignee: Fukuoka University
    Inventors: Kosei Shioji, Hiroyuki Nakagawa, Kentaro Okuma
  • Patent number: 8410177
    Abstract: A compound has Formula VIII where, X is —C(O)R, —C(O)OR, —CN, —NO2, —S(O)2R?, —P(O)(OR)2; each R is individually H, alkyl, or alkenyl; R? is alkyl or akenyl; R1 is aryl, alkenyl, arylalkenyl, heterocyclyl, or heteroaryl; and R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11 are individually H, alkoxy, or hydroxy. In some cases, X is NO2. Pharmaceutical compositions of the compound of Formula VIII with a pharmaceutically acceptable carrier may be prepared. The compounds may be used for inhibition of cyclooxygenase-2.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 2, 2013
    Assignee: Indian Institute of Technology Bombay
    Inventors: Irishi N. N. Namboothiri, Narasimham Ayyagari, Deena Jose
  • Patent number: 8377188
    Abstract: Disclosed is a polyfluoroalkylphosphonic acid oxyalkylene ester of the formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)[O(RO)mR?]d(OH)2-d (RO is a C2-C6 linear or branched oxyalkylene group, R? is a hydrogen atom or a C1-C20 alkyl group or aralkyl group, n is 1 to 6, a is 1 to 4, b is 1 to 3, c is 1 to 3, d is 1 or 2, and m is 1 to 100), which is a compound having a perfluoroalkyl group containing 6 or less carbon atoms and referred to as having low bioaccumulation potential, and exhibiting, when used as an active ingredient of a mold-releasing agent, mold release performance equivalent to that of a compound having a perfluoroalkyl group containing 8 or more carbon atoms. This compound is produced by subjecting a polyfluoroalkylphosphonic acid of the formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)(OH)2 and a polyalkyleneglycol or a monoether thereof of the formula: HO(RO)mR? to a condensation reaction.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: February 19, 2013
    Assignee: Unimatec Co., Ltd.
    Inventors: Yoshiyama Kaneumi, Seiichiro Murata, Katsuyuki Sato
  • Patent number: 8367078
    Abstract: The invention relates to kinase inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating disorders, especially cancer.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: February 5, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Peter P. Sayeski, György M. Keserü
  • Patent number: 8361993
    Abstract: The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4, —X denotes an oxygen atom or an N—R3 group, —R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and —R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: January 29, 2013
    Assignees: Universite de Nantes, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Maxim Egorov, Yannick Fortun, Dominique Heymann, Jacques Lebreton, Monique Mathe, Marc Padrines, Francoise Redini
  • Patent number: 8313573
    Abstract: Disclosed is a mold-releasing agent comprising, as active ingredients, a polyfluoroalkylphosphonic acid represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)(OH)2 (n: an integer of 1 to 6, a: an integer of 1 to 4, b: an integer of 1 to 3, c: an integer of 1 to 3), or a salt thereof and a polyfluoroalkylphosphonic acid oxyalkylene ester represented by the general formula: CnF2n+1(CH2CF2)a(CF2CF2)b(CH2CH2)cP(O)[O(RO)mR?]d(OH)2?d (RO: a C2-C6 linear or branched oxyalkylene group, R?: a hydrogen atom, a C1-C20 alkyl group, or aralkyl group, n: an integer of 1 to 6, a: an integer of 1 to 4, b: an integer of 1 to 3, c: an integer of 1 to 3, d: an integer of 1 or 2, m: an integer of 1 to 100).
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: November 20, 2012
    Assignee: Unimatec Co., Ltd.
    Inventors: Yoshiyama Kaneumi, Seiichiro Murata, Katsuyuki Sato
  • Patent number: 8293938
    Abstract: The invention relates to alkylphosphonous acids, salts and esters of formula (I) A-P(?O)(OX)—H (I) wherein A is C2-C20alkyl, C2-C20alkylene, and C8-C20 alkaryl are optionally substituted, and X is H, alkyl, aryl, alkylaryl, alkenyl, substituted alkyl, aryl, alkaryl, alkenyl, ammonium, primary, secondary, tertiary, quaternary alkyl and/or aryl ammonium, an alkali metal, an alkaline earth metal, a metal of the third and fourth main group and the second, fourth and eight sub-group or a metal of the lanthanoid group. The invention also relates to methods for producing same and to the uses of said compounds.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: October 23, 2012
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Michael Hill, Harald Bauer, Werner Krause
  • Patent number: 8278375
    Abstract: Mixtures of three types of linear, branched or cyclic phosphates are useful flame retardants, especially for thermoplastic resins or as functional additives in polymer matrices.
    Type: Grant
    Filed: July 5, 2006
    Date of Patent: October 2, 2012
    Assignee: Rhodia UK Limited
    Inventors: Vincent Schanen, Dwight Shamblee, Gleb Priimov, Julie Ann Salter
  • Patent number: 8278456
    Abstract: The present invention is directed to the synthesis and stabilization of neutral molecules containing homonuclear single or multiple bonds, methods of preparation, and uses thereof.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 2, 2012
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Gregory H. Robinson, Yuzhong Wang
  • Publication number: 20120220803
    Abstract: A production process of a trialkylphosphine according to the present invention includes: a first step of forming a trialkylphosphine by reaction of an organic metal compound and an organic phosphorous compound in an ether solvent having a difference in boiling point with the trialkylphosphine formed such that the difference in boiling point is in a range of 0° C. to 20° C.; a second step of obtaining a silver complex by absorption of a gas phase of the first step into an aqueous solution of AgI and KI; a third step of heating the silver complex obtained in the second step, in a metallic reaction vessel, at a temperature of 170° C. to 350° C. in a reduced pressure atmosphere of 1.333×10?7 MPa to 6.133×10?2 MPa; and a fourth step of cooling a gas product of the third step at a very low temperature range of ?196° C. to ?50° C. to trap the trialkylphosphine.
    Type: Application
    Filed: November 19, 2010
    Publication date: August 30, 2012
    Applicant: Central Glass Company, Limited
    Inventors: Toshihisa Ide, Tatsuya Irie
  • Patent number: 8247539
    Abstract: The invention concerns a process for preparing a hybrid organic-inorganic material (HOIM) with phosphorus-containing bridges between the surface of an inorganic substrate containing an element M and one or more organic groups of the covalent M-O-P-R type, said process using, as a precursor for said organic group or groups, at least one organophosphorus acid halide with formula RxP(O)Xy in which x=1 or 2, y=3?x, X being a halogen and R designating at least one organic alkyl, aryl or aryl-alkyl group. Non-exhaustive applications for the hybrid organic-inorganic material obtained by the process of the invention are in the fields of anti-corrosion, lubrication, microelectronics, nanotechnologies, composite materials, heterogeneous catalysis, supported catalysis, depollution and biomedical applications.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: August 21, 2012
    Assignee: IFP Energies Nouvelles
    Inventors: Renaud Revel, Florence Brodard-Severac, Gilles Guerrero, Hubert Mutin, Alain Forestiere, Alexandra Chaumonnot
  • Publication number: 20120190795
    Abstract: Provided is a low-cost, highly active, environmentally friendly living radical polymerization catalyst which does not require a radical initiator. An organic compound having an oxidation-reduction capability is used as a catalyst. Even if a radical initiator is not used, a monomer can be subjected to a radical polymerization to obtain a polymer having narrow molecular weight distribution. The cost of the living radical polymerization can be remarkably reduced. It is made possible to prevent adverse effects of using a radical initiator. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages of the catalyst such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (which do not require a post-treatment for a molded article), etc.
    Type: Application
    Filed: May 10, 2010
    Publication date: July 26, 2012
    Inventors: Atsushi Goto, Yoshinobu Tsujii, Takeshi Fukuda
  • Patent number: 8207367
    Abstract: The present invention relates to a method of producing a polymerizable phosphate containing at least one selected from polymerizable phosphates represented by formula (II), (III) or (IV) by a batch reaction, including a step of adding a compound represented by formula (I) into a mixture of a polymerizable phosphate reaction product containing at least one selected from polymerizable phosphates represented by formula (II), (III) or (IV), obtained by a pre-batch reaction, and phosphoric acid anhydride to react them: wherein R1 represents H or a C1-4 alkyl group, R2 represents a C2-6 alkylene group and n denotes an integer from 1 to 3.
    Type: Grant
    Filed: December 26, 2006
    Date of Patent: June 26, 2012
    Assignee: Kao Corporation
    Inventors: Minoru Kurata, Keishi Shimokawa
  • Patent number: 8193167
    Abstract: Compounds and compositions are provided for treatment, prevention, or amelioration of a variety of medical disorders associated with viral infections, cell proliferation and bone metabolism. The compounds provided herein are alkyl esters of phosphonates.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: June 5, 2012
    Assignees: The Regents of the University of California, The United States of America, Department of Veterans Affairs
    Inventors: Karl Y. Hostetler, W. Brad Wan
  • Patent number: 8182789
    Abstract: A bisphosphonoamine compound represented by the following formula (I): wherein R1, R2, R3, R4 and R5 are independently an alkyl group having 1 to 6 carbon atoms, and n is an integer of 1 to 6, is extremely useful as an intermediate for preparing a technetium nitride complex for radiodiagnostic imaging.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: May 22, 2012
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Francesco Tisato, Fiorenzo Refosco, Cristina Bolzati, Stefania Agostini, Marina Porchia, Mario Cavazza-Ceccato, Shinji Tokunaga
  • Patent number: 8148443
    Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?xHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1, 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFWRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: April 3, 2012
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
  • Patent number: 8129568
    Abstract: A composition comprising a compound of formula (I) or (II): wherein r and q are independently integers of 1 to 3; Rf is linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; j is an integer 0 or 1, or a mixture thereof, x is 1 or 2, Z is —O— or —S—, X is hydrogen or M, and M is an ammonium ion, an alkali metal ion, or an alkanolammonium ion is disclosed.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: March 6, 2012
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Sheng Peng, Stephen James Getty, Xianjun Meng
  • Patent number: 8129567
    Abstract: A composition which provides surface effects to substrates comprising a polymer containing at least one urea linkage prepared by (i) reacting (1) at least one organic diioscyanate, polyisocyanate, or mixture thereof, and (2) at least one fluorochemical compound of Formula I Rf—O(CF2CF2)r(CH2CH2)q(R1)sXH??Formula (I) wherein Rf is a linear or branched C1 to C7 perfluoroalkyl optionally interrupted by one to three oxygen atoms, r is 1 to 3, q is 1 to 3, s is 0 or 1, X is O, S, or NR2 wherein R2 is H, or C1 to C6 alkyl, and R1 is a divalent radical selected from —S(CH2)n—, p is 1 to 50, and R3, R4 and R5 are each independently H or C1 to C6 alkyl; (ii) and then reacting with (3) water, a linking agent, or a mixture thereof.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: March 6, 2012
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Sheng Peng, Stephen James Getty, Timothy Edward Hopkins, Ying Wang
  • Patent number: 8049040
    Abstract: Fluorophosphate containing an ethylene-tetrafluoroethylene moiety of formula (I) or (II): (A)w-P(O)(O?M+)3-w??(I) or wherein A is Rf—(CH2)k—[(CF2CF2)y—(CH2CH2)z]mO and contains from about 8 to about 22 carbon atoms; Rf is CnF2n+1; n and k are each independently 1 to about 6; y, z, and m are each independently 1, 2, 3, or mixture thereof; w is 1 or 2 or a mixture thereof; and M is hydrogen, ammonium ion, an alkali metal ion, or an alkanolammonium ion, said fluorophosphate useful as a surfactant for altering the surface behavior of a liquid by addition thereto, and for providing surface effects to a substrate treated with a composition containing the fluorophosphate.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: November 1, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Weiming Qiu, Xiuling Shirley Wang
  • Publication number: 20110263878
    Abstract: The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the delta-9-tetrahydrocannabinol compound or derivative thereof. Another aspect of the present invention relates to a process for preparation of a cannabidiol or cannabidiolate compound involving reacting a first starting compound with a second starting compound in the presence of a metal triflate catalyst, under conditions effective to form the cannabidiol or cannabidiolate compound. The present invention also relates to a compound of the formula: where R8, R9, and R10 are the same or different and independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or halo, with R1, R2, and R3 defined herein.
    Type: Application
    Filed: May 16, 2011
    Publication date: October 27, 2011
    Applicant: Albany Molecular Research, Inc.
    Inventors: David C. BURDICK, Steven J. Collier, Betina Biolatto, Harold Meckler
  • Publication number: 20110215274
    Abstract: Ferroelectric liquid crystal compositions including organic ion pair compounds wherein image sticking is reduced or eliminated. Use of the ferroelectric liquid crystal compositions in a ferroelectric liquid crystal display device allows for rapid image refresh rates without required a DC-balancing algorithm. The organic ion pair compounds provide electrical resistivity values for the compositions that result in reduced image sticking when the compositions are used in FLC display devices.
    Type: Application
    Filed: January 14, 2011
    Publication date: September 8, 2011
    Inventors: Cory Pecinovsky, William Thurmes, Brion C. Koprowski
  • Patent number: 7989663
    Abstract: Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: August 2, 2011
    Assignee: Echelon Biosciences Incorporated
    Inventors: Colin Ferguson, Glenn Prestwich
  • Patent number: 7968752
    Abstract: Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: June 28, 2011
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Ving Lee, Jacob J. Plattner, Stephen J. Benkovic, Stephen J. Baker, Kirk R. Maples, Carolyn Bellinger-Kawahara, Tsutomu Akama, Yong-Kang Zhang, Rajeshwar Singh, Vittorio A. Sauro
  • Patent number: 7955525
    Abstract: Disclosed is an oil composition wherein the oil contains measurable amounts of peroxide resulting from peroxidation, and also includes an effective amount of a peroxide-reducing phosphorous compound, preferably an alkyl/aryl substituted phosphite compound or phosphinic acid (H3PO2) and its derivatives.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: June 7, 2011
    Assignee: Galata Chemicals, LLC
    Inventors: Michael G. Denoux, Ritchie Tregre, Garrett Mineo
  • Patent number: 7951975
    Abstract: A composition comprising a compound of formula (I) or (II): wherein r and q are independently integers of 1 to 3; Rf is linear or branched chain perfluoroalkyl group having 1 to 6 carbon atoms; j is an integer 0 or 1, or a mixture thereof, x is 1 or 2, Z is —O— or —S—, X is hydrogen or M, and M is an ammonium ion, an alkali metal ion, or an alkanolammonium ion is disclosed.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: May 31, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Sheng Peng, Stephen James Getty, Xianjun Meng
  • Patent number: 7939588
    Abstract: A composition includes a salt of a carboxyethyl phosphinate ester compound. Additionally, the composition may also include a polymeric resin, such as a thermoplastic resin. The composition may have improved physical and chemical properties including flame retardancy, thermal stability, and hygroscopicity.
    Type: Grant
    Filed: November 27, 2006
    Date of Patent: May 10, 2011
    Assignee: Cheil Industries Inc
    Inventors: Sang Hyun Hong, Jeong Hwan Ku, Su Hak Bae, Jin Hwan Choi, Jin Hwan Kim, Min Soo Lee