Sulfur Or Oxygen Containing Patents (Class 568/11)
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Patent number: 7342124Abstract: Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.Type: GrantFiled: April 2, 2004Date of Patent: March 11, 2008Assignees: The Trustees Of The University Of Pennsylvania, Kosan Biosciences, Inc.Inventors: David C. Myles, Mark Burlingame, Simon James Shaw, Kurt F. Sundermann, Brian Scott Freeze, Ignació Brouard Martin, Tomoyasu Hirose, Amos B. Smith, III
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Patent number: 7230136Abstract: The invention relates to a process for synthesizing tertiary phosphines by reacting halophosphines with organomagnesium compounds in the presence of copper compounds and optionally of salts.Type: GrantFiled: April 17, 2003Date of Patent: June 12, 2007Assignee: LANXESS Deutschland GmbHInventors: Florian Rampf, Hans-Christian Militzer
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Patent number: 7227041Abstract: The present invention is generally directed to electroluminescent Ir(III) compounds with phosphinoalkoxides and phenylpyridines or phenylpyrimidines, and devices that are made with the Ir(III) compounds.Type: GrantFiled: April 13, 2005Date of Patent: June 5, 2007Assignee: E. I. du Pont de Nemours and CompanyInventors: Vladimir Grushin, Viacheslav A. Petrov
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Patent number: 7208605Abstract: One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze a Bronsted-acid-catalyzed chemical reaction. A third aspect of the present invention relates to ionic liquids comprising a pendant nucleophilic group, e.g., an amine. Still another aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to catalyze a nucleophile-assisted chemical reaction. A fifth aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to remove a gaseous impurity, e.g., carbon dioxide, from a gas, e.g., sour natural gas.Type: GrantFiled: April 4, 2003Date of Patent: April 24, 2007Assignee: University of South AlabamaInventor: James Hillard Davis, Jr.
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Patent number: 7074738Abstract: A curing accelerator which is suitable for various curable resin compositions, an epoxy resin composition having excellent curability, storage stability and fluidity, and a semiconductor device having excellent solder cracking resistance and moisture resistance reliability are provided. The epoxy resin composition includes a compound (A) having two or more epoxy groups in one molecule, a compound (B) having two or more phenolic hydroxyl groups in one molecule, trisubstituted phosphoniophenolate or a salt thereof as a curing accelerator (C), and an inorganic filler (D).Type: GrantFiled: June 4, 2003Date of Patent: July 11, 2006Assignee: Sumitomo Bakelite Company LimitedInventors: Akiko Okubo, Yoshiyuki Goh, Yoshihito Akiyama, Hiroshi Hirose, Hirotaka Nonaka, Maki Sugawara
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Patent number: 6849669Abstract: The invention relates to macromolecular hydrophilic photocrosslinkers having polymeric backbones of substituted ethylene groups carrying photoactive groups. The photocrosslinkers are capable of producing, when being exposed to light of determined wavelengths above 305 nm, radicals which are retained on the macromolecular photocrosslinkers and reacting so as to accomplish a crosslinked network structure. The invention further relates to the preparation of photocrosslinkers, their use in different aqueous systems and their utility in production of medical devices including ophthalmic lenses.Type: GrantFiled: March 16, 2000Date of Patent: February 1, 2005Assignee: Pharmacia Groningen BVInventors: Kenneth A. Hodd, Keith Alfred Dillingham, Jacqueline deGroot, Hendrik Haitjema
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Patent number: 6841638Abstract: The invention relates to an ionic compound corresponding to the formula [R1X1(Z1)—Q?—X2(Z2)—R2]m Mm+ in which Mm+ is a cation of valency m, each of the groups Xi is S?Z3, S?Z4, P—R3 or P—R4; Q is N, CR5, CCN or CSO2R5, each of the groups Zi is ?O, ?NC?N, ?C(C?N)2, ?NS (?Z)2R6 or ?C[S(?Z)2R6]2, each of the groups Ri, is Y, YO—, YS—, Y2N— or F, Y represents a monovalent organic radical or alternatively Y is a repeating unit of a polymeric frame. The compounds are useful for producing ion conducting materials or electrolytes, as catalysts and for doping polymers.Type: GrantFiled: February 14, 2003Date of Patent: January 11, 2005Assignees: ACEP Inc., Universite de Montreal, Centre National de la Recherche Scientifique, Institute of Organic Chemistry National Academy of Sciences of UkraineInventors: Michel Armand, Christophe Michot, Yurii Yagupolskii, Lev Yagupolskii, Andrej Bezdudny, Natalya Kondratenko
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Patent number: 6841304Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N?(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.Type: GrantFiled: November 9, 2001Date of Patent: January 11, 2005Assignees: ACEP, Inc., Centre National de la Recherche Scientifique, Universite de MontrealInventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
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Patent number: 6812365Abstract: The present invention provides novel disulfone compounds and methods of preparing and using those compounds to further prepare biologically relevant gem-disulfone analogs of natural enzyme substrates. Methods of using a variety of disulfone compounds as reagents capable of forming symmetrical and non-symmetrical &agr;, &bgr; unsaturated gem-disulfones are also provided. There is also provided a disulfone reagent which reacts with both aromatic and aliphatic aldehydes in good to moderate yield to give exclusively the trans isomer. In accordance with further aspects of the present invention, a methodology for stereospecifically preparing potential gem-disulfone enzyme inhibitors is provided. A synthetic design which allows easy substitution of functional groups so that a number of substrate analogs can be synthesized readily is also provided.Type: GrantFiled: November 5, 2002Date of Patent: November 2, 2004Assignee: The Arizona Disease Control Research CommissionInventors: Jacqueline Gervay-Hague, Michael J. Hadd
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Publication number: 20040204612Abstract: A disulfone compound represented by the general formula (3): 1Type: ApplicationFiled: March 2, 2004Publication date: October 14, 2004Inventors: Shinzo Seko, Naoto Konya, Toshiya Takahashi
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Publication number: 20040110990Abstract: The invention relates to a process for catalytically reducing substituted benzonitriles to substituted benzaldehydes in the presence of aqueous formic acid, of a nickel- and aluminium-containing catalyst and hydrogen.Type: ApplicationFiled: August 14, 2003Publication date: June 10, 2004Inventors: Markus Eckert, Friedrich Durholz
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Patent number: 6743936Abstract: There are disclosed amphoteric nano-sized metal oxide particles functionalized with silyl esters of a phosphonate and composites thereof with an acrylate-based monomer, including liquid crystal monomers photopolymerizable at ambient temperature. Also disclosed are the method making such functionalized particular by reacting a metal oxide with a silyl ester of a phosphonate in the presence of a non-aqueous solvent and in an inert atmosphere and the method of making the composites wherein the functionalized particles are admixed with an acrylate-based matrix monomer, including liquid crystal monomers photopolymerizable at ambient temperature. Further disclosed is the method of dental repair wherein the composites are applied to a tooth and photopolymerized.Type: GrantFiled: October 19, 2000Date of Patent: June 1, 2004Assignees: Southwest Research Insittute, Board of Regents, The University of Texas SystemInventors: Stephen T. Wellinghoff, Hong Dixon, Henry R. Rawls, Barry K. Norling
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Patent number: 6710153Abstract: A process for the production of phosphonium phenolates is disclosed. The process entails reacting a phosphonium halide and phenol in an aqueous alkaline solution.Type: GrantFiled: June 17, 2002Date of Patent: March 23, 2004Assignee: Bayer AktiengesellschaftInventors: Lothar Bunzel, Uwe Hucks, Annett König, Silke Kratschmer
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Publication number: 20040035293Abstract: One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze a Bronsted-acid-catalyzed chemical reaction. A third aspect of the present invention relates to ionic liquids comprising a pendant nucleophilic group, e.g., an amine. Still another aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to catalyze a nucleophile-assisted chemical reaction. A fifth aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to remove a gaseous impurity, e.g., carbon dioxide, from a gas, e.g., sour natural gas.Type: ApplicationFiled: April 4, 2003Publication date: February 26, 2004Inventor: James Hillard Davis
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Patent number: 6498277Abstract: The present invention provides novel disulfone compounds and methods of preparing and using those compounds to further prepare biologically relevant gem-disulfone analogs of natural enzyme substrates. Methods of using a variety of disulfone compounds as reagents capable of forming symmetrical and non-symmetrical &agr;, &bgr; unsaturated gem-disulfones are also provided. There is also provided a disulfone reagent which reacts with both aromatic and aliphatic aldehydes in good to moderate yield to give exclusively the trans isomer. In accordance with further aspects of the present invention, a methodology for stereospecifically preparing potential gem-disulfone enzyme inhibitors is provided. A synthetic design which allows easy substitution of functional groups so that a number of substrate analogs can be synthesized readily is also provided.Type: GrantFiled: June 14, 2000Date of Patent: December 24, 2002Assignee: The Arizona Disease Control Research CommissionInventors: Jacqueline Gervay-Hague, Michael J. Hadd
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Patent number: 6476273Abstract: A process for preparing phosphonium phenolate is disclosed. The process entails a reaction of phosphonium halide with phenol in an aqueous alkaline solution at a temperature of 0 to 55° C. The molar ratio of phenol to phosphonium halide is between 2:1 to 10:1 and the pH of the solution is 9.5 to 11. An optional embodiment entails carrying out the reaction in the further presence of alcohol.Type: GrantFiled: December 21, 1999Date of Patent: November 5, 2002Assignee: Bayer AktiengesellschaftInventors: Annett König, Lothar Bunzel, Uwe Hucks
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Publication number: 20020055045Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N−(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.Type: ApplicationFiled: November 9, 2001Publication date: May 9, 2002Inventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
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Patent number: 6365301Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N−(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalized, and can be used, inter alia, as electrolyte.Type: GrantFiled: September 7, 1999Date of Patent: April 2, 2002Assignees: ACEP, Inc., Centre National de la Recherche Scientifique, Universite de MontrealInventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
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Patent number: 6339103Abstract: The new compound, dimethy[3-(propoxycarbonylamino)propyl]ammonium O-ethylphosphonate, having fungicidal activity, its preparation, compositions comprising it and methods for its use in agriculture.Type: GrantFiled: December 12, 2000Date of Patent: January 15, 2002Assignee: Aventis CropScience UK LimitedInventors: Norman John De'Ath, John Klostermyer, Albert Schirring, Michael Alan Webb, Geoffrey Gower Briggs
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Patent number: 6331652Abstract: There are disclosed a sulfonaldehyde derivative of formula (2): a phosphonium salt of formula (3): processes for producing the same and a sulfone derivative of formula (4): a process for producing the same and a process for producing lycopene therefrom.Type: GrantFiled: July 24, 2000Date of Patent: December 18, 2001Assignee: Sumitomo Chemical Company, LimitedInventors: Naoto Konya, Shinzo Seko
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Publication number: 20010005765Abstract: A process for preparing phosphonium phenolate is disclosed. The process entails a reaction of phosphonium halide with phenol in an aqueous alkaline solution at a temperature of 0 to 55° C. The molar ratio of phenol to phosphonium halide is between 2:1 to 10:1 and the pH of the solution is 9.5 to 11. An optional embodiment entails carrying out the reaction in the further presence of alcohol.Type: ApplicationFiled: December 21, 1999Publication date: June 28, 2001Inventors: ANNETT KONIG, LOTHAR BUNZEL, UWE HUCKS
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Patent number: 6103940Abstract: Preparing (3R, 3'R)-zeaxanthin of the formula I ##STR1## starting from (4-hydroxy-2,2,6-trimethylcyclohexanone of the formula II ##STR2## via the novel intermediates (4R,6R)-1-formyl-2,2,6-trimethyl-7-oxabicyclo[2.2.1]heptane of the formula IV ##STR3## (4R,6R)-1-(3-oxo-1-butenyl)-2,2,6-trimethyl-7-oxabicyclo[2.2.1]heptane of the formula V ##STR4## (4R,6R)-1-(3- hydroxy-3-methyl-1,4-pentadienyl)-2,2,6-trimethyl-7-oxabicyclo[2.2.1]heptan e of the formula VI ##STR5## [5-(4R,6R)-(4-hydr oxy-2,2,6-trimethyl-1-cyclohexylidene)-3-methyl-1,3-pentadienyl]triarylphos phonium salt of the formula iso-III ##STR6## where Ar is aryl and X is one equivalent of an anion of a strong acid. The (4R,6R)-1-formyl-2,2,6-trimethyl-7-oxabicyclo[2.2.1]heptane of formula IV is obtained by reacting the ketone of the formula II with dichloromethyllithium, which can be prepared by metallation of dichloromethane with butyllithium or lithium diisopropylamide.Type: GrantFiled: June 4, 1998Date of Patent: August 15, 2000Assignee: BASF AktiengesellschaftInventors: Joachim Paust, Wolfgang Kriegl
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Covalent lipid-phosphono-carboxylic acid conjugates and application thereof as antiviral medicaments
Patent number: 5955452Abstract: The present invention concerns new lipid derivatives of phosphonocarboxylic acids of the general formula I, ##STR1## in which the meaning of the symbols is elucidated in the description, tautomers thereof and their physiologically tolerated salts of inorganic and organic bases as well as processes for the production thereof and pharmaceutical agents containing these compounds.Type: GrantFiled: August 26, 1998Date of Patent: September 21, 1999Assignee: Roche Diagnostics GmbHInventors: Harald Zilch, Dieter Herrmann, Hans-George Opitz, Gerd Zimmermann, Edgar Voss -
Patent number: 5756843Abstract: Quaternary salts having a double helix structure are prepared by the reaction of dihydroxyaromatic compound, preferably a bisphenol, with an alkali metal hydroxide and a quaternary salt, such as a tetraalkylammonium or hexaalkylguanidinium chloride. The quaternary salts and their alkaline hydrolysis products are useful as catalysts in various reactions, including imide formation from bisphenol salts and halo- or nitro-substituted phthalimides and redistribution and equilibration of polycarbonates.Type: GrantFiled: December 17, 1996Date of Patent: May 26, 1998Assignee: General Electric CompanyInventors: Jimmy Lynn Webb, Matthew Hal Littlejohn, Joseph John Caringi, Thomas Link Guggenheim, Robert Joseph Nick, Patrick Joseph McCloskey, Joseph Anthony King, Jr.
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Patent number: 5734085Abstract: A compound having the formula: ##STR1## where A.sup.- is a counterion; R.sup.1, R.sup.2, R.sup.3, and R.sup.4, independently, comprise (a) a non-fluorinated alkyl, cycloalkyl, aryl, or aralkyl group; (b) an onium-containing group; or (c) a group having the formula --(CH.sub.2).sub.n --Y--R.sup.5 in which n is at least two; Y is a spacer arm comprising a --CH.sub.2 --, --O--, --OCH.sub.2 --, --S--, --SO.sub.2 --, or --Z--SO.sub.2 -- group; Z is an --R.sup.6 --O--, --N(R.sup.7)-- group, or --N(H)--; R.sup.6 is a substituted or unsubstituted phenylene group; R.sup.7 is H or a non-fluorinated alkyl, cycloalkyl, aryl, or alkaryl group; and R.sup.5 is a fluorinated group, perfluorinated group, or combination thereof, with the proviso that (i) at least one of R.sup.1, R.sup.2, R.sup.3, and R.sup.4 comprises a group having the formula --(CH.sub.2).sub.n --Y--R.sup.5 ; and (ii) the total number of fluorine atoms in said compound is at least 5.Type: GrantFiled: December 21, 1995Date of Patent: March 31, 1998Assignee: Minnesota Mining and Manufacturing CompanyInventors: William D. Coggio, Richard M. Flynn, George G. Moore
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Patent number: 5717083Abstract: Compounds are provided having structure (I), wherein the L groups are backbone segments, the Y and T groups are functional groups for interacting with target molecules of interest, the X groups are oxygen or sulfur and the E groups are H, conjugate groups or intermediate groups used during the synthesis of the compounds and wherein the compounds are prepared using H phosphonate type chemistry wherein the functional groups are added during an oxidation step or during a coupling step.Type: GrantFiled: August 19, 1996Date of Patent: February 10, 1998Assignee: ISIS Pharmaceuticals, Inc.Inventors: Phillip Dan Cook, Oscar Acevedo, Normand Hebert
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Patent number: 5693842Abstract: The invention relates to a process for preparing phosphorus-containing compounds of the formula I ##STR1## in which R.sup.1 and R.sup.2 are an alkyl radical having 1 to 8 carbon atoms, a cyclohexyl radical, a cyclopentyl radical, an aryl radical or a halogen-, alkyl- or alkoxy-substituted aryl radical, where R.sup.1 and R.sup.2 together with the phosphorus atom can also form a ring, n and m=0 or 1 and R.sup.3 and R.sup.4 are alkyl radicals having 1 to 4 carbon atoms or n=0, m=0 or 1 and R.sup.3 and R.sup.4 are H, by adding compounds of the formula II ##STR2## into dialkyl esters of fumaric acid or of maleic acid of the formula (III) or dialkyl esters of itaconic acid of the formula (IV) ##STR3## in which R.sup.3 and R.sup.4 have the meaning given above, and, optionally reacting an alkyl ester of a phosphorus-containing dicarboxylic acid of the formula (I), where n=0, with water in the presence of catalytic amounts of an acid to give the phosphorus-containing dicarboxylic acid.Type: GrantFiled: September 5, 1996Date of Patent: December 2, 1997Assignee: Hoechst AGInventors: Hans-Jerg Kleiner, Volker Freudenberger, Peter Klein
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Patent number: 5637684Abstract: Compounds are provided having the structure: ##STR1## wherein the L groups are spanner or linker units, the Y and T group are functional groups for interacting with target molecules of interest, the X groups are oxygen or sulfur and the E groups are H, conjugate groups or intermediate groups used during the synthesis of the compounds are prepared using H phosphonate type chemistry wherein the functional groups are added during an oxidization step.Type: GrantFiled: February 23, 1994Date of Patent: June 10, 1997Assignee: ISIS Pharmaceuticals, Inc.Inventors: Phillip D. Cook, Oscar Acevedo, Normand Hebert
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Patent number: 5625099Abstract: Abstract of the Disclosure: Compounds of the formula I ##STR1## where R.sup.1 is H or C.sub.1 -C.sub.4 -alkyl, R.sup.2 is C.sub.1 -C.sub.4 -alkyl and R.sup.3 is an ether, silyl ether or acetal protective group which can be converted into a hydroxyl group by hydrolysis, in particular one of the radicals ##STR2## and a process for preparing these compounds by reacting an alkenyne of the formula II ##STR3## in an inert solvent in the presence of lithium amide with a cyclohexenone of the formula III ##STR4## and the use of the compounds of the formula I for preparing astaxanthin, are described.Type: GrantFiled: May 23, 1995Date of Patent: April 29, 1997Inventors: Hansgeorg Ernst, Walter Dobler, Joachim Paust, Udo Rheude
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Patent number: 5616759Abstract: Cyclohexylidene compounds of the structure: ##STR1## where X.sup.1 and X.sup.2, which may be the same or different, is hydrogen or a hydroxy-protecting group, and Y is --POPh.sub.2, or --PO (OAlkyl).sub.2, or --SO.sub.2 Ar, or --Si(Alkyl).sub.3. The compounds are used as intermediates in the preparation of 19-nor-vitamin D compounds.Type: GrantFiled: May 16, 1995Date of Patent: April 1, 1997Assignee: Wisconsin Alumni Research FoundationInventors: Hector F. DeLuca, Heinrich K. Schnoes, Kato L. Perlman, Rolf E. Swenson
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Patent number: 5525580Abstract: Compounds represented by general formula (I), herbicides or selective herbicides for paddy field containing said compounds as active ingredients, method of controlling growth of undesirable plants by applying the herbicides on places where control is desired. ##STR1## wherein A represents a --S(O)nR.sup.1 in which n is 0 or 2 and R.sup.1 represents a (substituted) lower alkyl; a cycloalkyl; a (substituted) benzyl; a (substituted) phenyl; or a --OR.sup.2 in which R.sup.2 represents a (substituted) phenyl;B represents a halogen, a nitro, a lower alkyl, or a lower alkylsulfonyl;D represents a hydrogen, a lower alkyl, a lower alkoxy, a lower alkoxymethyl, or a lower alkoxycarbonyl;E represents a halogen, a (substituted) lower alkoxy, a lower alkylthio, a (substituted) lower alkylsulfonyl, or a lower alkylsulfonyloxy.The herbicides of the present invention can prevent a wide variety of noxious weeds and further selectively prevent weeds on paddy field with considerably reduced phytotoxicities on rice plant.Type: GrantFiled: January 14, 1994Date of Patent: June 11, 1996Assignee: SDS Biotech K.K.Inventors: Kenichi Komatsubara, Tadashi Sato, Kenji Mikami, Yuji Yamada
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Patent number: 5508273Abstract: Compounds represented by the formula I: ##STR1## are disclosed as agents for use in treating bone wasting diseases.Type: GrantFiled: December 30, 1993Date of Patent: April 16, 1996Assignee: Ortho Pharmaceutical CorporationInventors: Scott Beers, Elizabeth A. Malloy, Charles Schwender
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Patent number: 5424438Abstract: Polishes for metal surfaces, based on dispersions of waxes, fluorinated polymers and perfluoropolyoxyalkylene oils acquire high gloss characteristics combined with improved water-repellency and resistance to soiling of 0.1-5% by weight of at least a cationic emulsifier comprised in the general formula(I) R-L-Q.sup.+ X.sup.-where:R=a chain of perfluoropolyoxyalkylene units;L=a divalent organic group;Q=a polar group;X=a halogen, or a group of formulaCH.sub.3 -Phenylene-SO.sub.3.sup.-R"SO.sub.3.sup.-R"=F-(CF.sub.2).sub.m -;t=1 or 2;m=1-4.The polished containing the emulsifiers of formula (I) as well as the compounds comprised in said formula are claimed as new products.Type: GrantFiled: January 6, 1994Date of Patent: June 13, 1995Assignee: Ausimont S.p.A.Inventors: Alba Chittofrati, Viviana Boselli, Giovanni Gavazzi, Ezio Strepparola, Renato Spiti, Silvia Tresoldi
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Patent number: 5366727Abstract: An antibacterial agent comprising as an active ingredient a vinylbenzyl phosphonium salt of the general formula (I), ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represent a hydrogen atom, a linear or branched alkyl group having 1 to 18 carbon atoms, an aryl group, a hydroxyl group, or an alkoxyl-substituted alkyl, aryl or aralkyl group, and X.sup.- is an anion; and/or a phosphonium salt polymer in which the vinylbenzyl phosphonium salt, a monomer, is polymerized.Type: GrantFiled: October 21, 1992Date of Patent: November 22, 1994Assignee: Nippon Chemical Industrial Co., Ltd.Inventors: Akihiko Kanazawa, Takeshi Endo, Tomiki Ikeda
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Patent number: 5276189Abstract: A process for the treatment of a quaternary onium salt is described. The process comprises the steps of (i) contacting an organic phase soaringly miscible in water containing a quaternary onium fluorine-containing carboxylate of RfCO.sub.2.sup.-+ AR.sup.1 R.sup.2 R.sup.3 R.sup.4 as defined in the present Specification with an aqueous phase containing a thiocyanate ion to form a quaternary onium thiocyanate in the organic phase and (ii) contacting the organic phase containing the quaternary onium thiocyanate with an aqueous solution containing a water-soluble oxidizing agent to decompose the thiocyanate ion and to form an easily ion exchangeable quaternary onium salt. Also, applications of this treatment to a process for preparing hexafluoropropylene oxide from hexafluoropropylene in a two-phase system of an aqueous phase and an organic phase by using a hypochlorite as an oxidizing agent in the presence of a quaternary onium salt as a catalyst are described.Type: GrantFiled: May 11, 1992Date of Patent: January 4, 1994Assignee: Asahi Kasei Kogyo K.K.Inventors: Masanori Ikeda, Yoshio Suzuki, Atsushi Aoshima
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Patent number: 5139561Abstract: A method for protecting growing plants against fungal or microbial plant pathogens which comprises applying thereto, or to the medium on which they are growing or to be grown, a composition comprising a water soluble tetrakis (hydroxymethyl) phosphonium salt.Type: GrantFiled: July 19, 1991Date of Patent: August 18, 1992Assignee: Albright & Wilson LimitedInventors: Robert E. Talbot, Kenneth G. Cooper
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Patent number: 5081273Abstract: This invention relates to a process for the preparation of insecticidally active compounds and to novel styrene derivatives useful as intermediates therein.Type: GrantFiled: November 30, 1989Date of Patent: January 14, 1992Assignee: Imperial Chemical Industries plcInventors: Michael J. Bushell, Ralph A. Raphael
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Patent number: 4895952Abstract: A polyfluoroalkylthiomethyl compound of the formula:R.sub.f (CH.sub.2).sub.m --S--CH.sub.2 --Ain which R.sub.f is a straight-chain or branched perfluoroalkyl radical containing from 2 to 16 carbon atoms, m is an integer from 1 to 4, and A is a hydroxyl group, a chlorine or bromine atom, an ammonium group derived from a secondary or tertiary amine, a phosphonium group, or an ionic or nonionic group --Q--(CH.sub.2).sub.n --Z, in which Q is an oxygen or sulphur atom, n the number 0, 1 or 2, and Z an unsubstituted or substituted alkyl, aryl or alkylaryl radical. The invention also comprises the method of making such compound and the use thereof as a surface-active agent.Type: GrantFiled: December 29, 1986Date of Patent: January 23, 1990Assignee: AtochemInventors: Frederique Marty, Emile Rouvier, Aime Cambon
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Patent number: 4894480Abstract: The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modifying anti-rheumatic agents and as immunosuppressants.Type: GrantFiled: December 16, 1988Date of Patent: January 16, 1990Assignee: Hoffmann-La Roche Inc.Inventors: Edward R. Aig, John W. Coffey, Allen J. Lovey, Michael Rosenberger
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Patent number: 4791139Abstract: A compound of formula: ##STR1## wherein W represents one or more substituents selected from halo, alkyl, alkoxy, alkoxyalkyl, haloalkyl and haloalkoxy or W represents a bidentate group linking adjacent carbon atoms selected from alkylene and alkylenedioxy; Y is a group of formula ##STR2## wherein X is a group of formula --(CF.sub.2).sub.n R.sup.3, where R.sup.3 is selected from hydrogen, chloro and fluoro, and n is one or two, R.sup.1 is selected from hydrogen, chloro, fluoro and hydroxy and R.sup.2 is selected from methyl, cyano, ethynyl and hydrogen; Q is selected from carbon bearing a hydrogen atom and nitrogen; and Z represents one or more substituents selected from fluoro, benzyl, phenoxy, chlorophenoxy, fluorophenoxy and bromophenoxy, or any isomer thereof. Processes for preparing these compounds and intermediates for use therein, insecticidal compositions containing these compounds and the use thereof are also disclosed.Type: GrantFiled: February 25, 1987Date of Patent: December 13, 1988Assignee: Imperial Chemical Industries PLCInventors: Michael J. Bushell, Robin A. E. Carr
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Patent number: 4761493Abstract: A quaternary phosphonium hydroxide, which is represented by the following general formula (II): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 mean independently an alkyl group having 1-8 carbon atoms, a phenyl group or a benzyl group, is prepared by dissolving a quaternary phosphonium halide represented by the following general formula (I): ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 has the same meaning as defined above and X denotes a chlorine, bromine or iodine atom, in a solvent selected from water, lower alcohols and aqueous lower alcohols, and then bringing the resultant solution into contact with a strongly basic anion exchange resin (OH-form).Type: GrantFiled: March 10, 1987Date of Patent: August 2, 1988Assignee: Hokko Chemical Industry Co., Ltd.Inventors: Masayuki Umeno, Satoshi Takita
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Patent number: 4694104Abstract: The invention relates to polyoxyalkylene quaternized salts as phase transfer catalysts for liquid/liquid phase cyclopropanation, substitution or addition reactions involving a normally liquid or solvent soluble olefinically unsaturated hydrocarbon and the process in which said quaternary compound is utilized. The involved quaternized salts are defined by the formula: ##STR1## wherein R is alkyl having 8 to 30 carbon atoms, blends thereof or alkyl-substituted phenyl of 10 to 24 carbon atoms;n has a value of from 2 to 14 and includes mixtures within said range;R.sub.1 and R.sub.2 are hydrogen atoms or one of R.sub.1 and R.sub.2 is methyl;R.sub.3, R.sub.4 and R.sub.5 are independently hydrogen, an alkyl radical of 1 to 6 carbon atoms or phenyl or one of R.sub.3, R.sub.4 and R.sub.5 is an .beta.-ethyl-alkali metal sulfonate;A is a phosphorous or a nitrogen atom; and halo is a chlorine or bromine ion.Type: GrantFiled: August 9, 1982Date of Patent: September 15, 1987Assignee: GAF CorporationInventors: Paritosh M. Chakrabarti, Sureshchandra G. Desai, Lindley S. Wood, Jr.
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Patent number: 4692504Abstract: A method is disclosed for deactivating a hydrocarbyl phosphonium salt catalyst of an epoxy resin fusion reaction. The method involves contacting the hydrocarbyl phosphonium salt catalyst with a sulfonic acid, such as p-toluenesulfonic acid or methane sulfonic acid. The method is particularly suited for deactivation of moisture-resistant phosphonium salts such as methylene bis(triphenyl phosphonium halide)s.Type: GrantFiled: April 30, 1986Date of Patent: September 8, 1987Assignee: Shell Oil CompanyInventor: Harry Frank
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Patent number: 4656310Abstract: Novel 9-phenyl 5,6-dimethyl-nona-2,4,6,8-tetraenoic acid,- tetraenal or tetraenol derivatives useful as anti-tumor agents.Type: GrantFiled: May 13, 1985Date of Patent: April 7, 1987Assignee: Hoffmann-La Roche Inc.Inventors: Werner Bollag, Rudolf Ruegg, Gottlieb Ryser
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Patent number: 4544770Abstract: Compounds of the formula: ##STR1## wherein R.sup.1 is a 2,6,6-trimethyl-1-cyclohexen-1-yl or 2,3,6-trimethylphenyl group, either of which may be unsubstituted or substituted by a hydroxy group or a protected hydroxy group, R.sup.2 is aryl, and X.sup.- is an anionare manufactured by hydrogenating a compound of the formula: ##STR2## wherein R.sup.1, R.sup.2 and X.crclbar. are as above, in an organic solvent or aqueous-organic solvent in the presence of a nickel-, palladium-, platinum-, cobalt-, rhodium-, iridium-, or ruthenium-containing catalyst.The process is suitable as an intermediate step in carotenoid and retinoid syntheses.Type: GrantFiled: July 11, 1983Date of Patent: October 1, 1985Assignee: Hoffmann-La Roche Inc.Inventor: Emil A. Broger
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Patent number: 4540823Abstract: Novel advanced epoxy resins are prepared using phosphine or phosphonium salt initiators bearing at least one hydroxyphenyl or thiophenyl groups. These phosphonium salt initiators are novel compositions of matter. The resulting resins contain reduced quantities of extractable phosphorus containing moieties.Type: GrantFiled: June 15, 1984Date of Patent: September 10, 1985Assignee: The Dow Chemical CompanyInventors: George A. Doorakian, Joseph W. Hanafin
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Patent number: 4532355Abstract: Novel 9-phenyl 5,6-dimethyl-nona-2,4,6,8-tetraenoic acid,-tetraenal or tetraenol derivatives useful as anti-tumor agents.Type: GrantFiled: September 13, 1982Date of Patent: July 30, 1985Assignee: Hoffmann-La Roche Inc.Inventors: Werner Bollag, Rudolf Ruegg, Gottlieb Ryser
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Patent number: 4507247Abstract: There are provided novel sulfonated Group Va ylides defined by the following Formula I: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.Type: GrantFiled: February 25, 1983Date of Patent: March 26, 1985Assignee: Gulf Research & Development CompanyInventors: David L. Beach, James J. Harrison
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Patent number: 4429161Abstract: Process for producing organic tertiary polyphosphine monooxides which comprises reacting an organic tertiary polyphosphine with an organic monofunctional alkylating agent to form an intermediate monophosphonium salt of the polyphosphine starting material and then hydrolyzing the salt so produced to the desired polyphosphine monooxide product.Type: GrantFiled: August 17, 1981Date of Patent: January 31, 1984Assignee: Union Carbide CorporationInventors: Anthony G. Abatjoglou, Louis A. Kapicak
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Patent number: 4396777Abstract: 1-Cycloalkyl phosphonium salts represented by the formula ##STR1## wherein: R is selected from the group consisting of lower alkyl, hydroxy lower alkyl, halo lower alkyl, amino lower alkyl, cyano lower alkyl, lower alkenyl with the limitation that the double bond is not on the carbon atom attached to the oxygen atom, benzyl, substituted benzyl and ##STR2## wherein q is O or 1 and R.sub.4 is selected from the group consisting of hydroxy, loweralkoxy, phenyl, substituted phenyl, and ##STR3## wherein R.sub.5 and R.sub.6 are the same or different members of the group consisting of hydrogen and loweralkyl or taken together form a 5 or 6 membered ring; m is 1, 2 or 3; n is 0 or 1; o is 0 or 1; p is 0 or 1; R.sub.1, R.sub.2 and R.sub.3 are the same or different members of the group consisting of hydrogen, lower alkyl, lower alkoxy and halo; and X is a pharmaceutically acceptable anion. The compounds are useful as analgesic agents.Type: GrantFiled: March 29, 1982Date of Patent: August 2, 1983Assignee: G. D. Searle & Co.Inventor: Richard A. Mueller