Ketone Containing Patents (Class 568/42)
  • Publication number: 20140353175
    Abstract: A process for derivatization of an elemental carbon surface comprising exposing the carbon surface to a reaction mixture containing a thiol and a free radical initiator, and inducing decomposition of the initiator to free radicals so that moieties from the thiol become covalently attached to the carbon surface. The process can derivatize carbon with a redox active compound having a functional group which can be converted electrochemically between reduced and oxidized forms. Such derivatized carbon may be used in an electrode of an electrochemical sensor.
    Type: Application
    Filed: December 21, 2012
    Publication date: December 4, 2014
    Inventors: Lynne Crawford, Nathan Lawrence, Timothy Jones
  • Publication number: 20140243404
    Abstract: This disclosure is related to halonium compounds useful for cyclization of polyenes, alkenoic acids, and alkenyl alkyl ethers, and halogenation of aromatic compounds. The synthesis of such halonium compounds, compounds made using such halonium compounds, and synthesis of natural compounds, including decalins, using the halonium compounds is also disclosed.
    Type: Application
    Filed: September 13, 2011
    Publication date: August 28, 2014
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Scott Alan Snyder, Daniel S. Treitler, Alexandria P. Brucks, Andreas Gollner, Maria I. Chiriac, Nathan E. Wright, Jason J. Pflueger, Steven P. Breazzano
  • Patent number: 8808702
    Abstract: Compounds useful as antiproliferative agents according to formula (I): wherein Ar1, Ar2, Ar3, m and n are as defined herein, salts, antibody conjugates, pharmaceutical compositions, methods of treatment, and synthetic methods are provided.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: August 19, 2014
    Assignee: Temple University-of the Commonwealth System of Higher Education
    Inventors: E. Premkumar Reddy, M. V. Ramana Reddy
  • Patent number: 8604234
    Abstract: The invention relates to a method for preparing acrolein from glycerol or glycerin, according to which dehydration of glycerol or glycerin is carried out in the presence of a catalyst which consists in at least one silica modified with zirconium dioxide, titanium dioxide or tungsten trioxide or any combination of these oxides, and a heteropolyacid. This method may be used for making 3-(methylthio)propionic aldehyde (MMP), 2-hydroxy-4-methylthiobutyronitrile (HMBTN), methionine or its analogs, from acrolein.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: December 10, 2013
    Assignees: Adisseo France S.A.S., Centre National de la Recherche Scientifique, Universite Lille 1-Sciences et Technologies
    Inventors: Sebastien Paul, Benjamin Katryniok, Franck Dumeignil, Mickael Capron
  • Publication number: 20130150479
    Abstract: The present invention provides a photocurable composition prepared using mercapto benzophenone compounds as key raw materials. The present invention aims to solve the problems existing in the prior photo-curing technology that low-molecular photoinitiators are easy to remain and migrate, while macromolecular photoinitiators has low initiation efficiency due to a low content of effective components and also has the problem of certain migration. The photocurable composition in the present invention can be easily prepared and has high addition efficiency with ethylenically unsaturated compounds, and the photocurable composition obtained by addition has no residual mercapto and has features of high initiation activity and zero migration rates when it is used in photocurable coatings, binder and ink formula.
    Type: Application
    Filed: February 7, 2013
    Publication date: June 13, 2013
    Applicant: Insight High Technology (Beijing) Co. Ltd.
    Inventor: Insight High Technology (Beijing) Co. Ltd.
  • Patent number: 8350051
    Abstract: A process for producing an ?-hydroxyketone compound, which comprises subjecting an aldehyde compound to a coupling reaction in the presence of an alkoxyimidazolidine compound represented by the formula (1) wherein R1? and R2? independently represent a hydrogen atom, etc., R3? and R4? independently represent a substituted or unsubstituted aryl group, etc. and R5? represents an alkyl group.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: January 8, 2013
    Assignee: Sumitomo Chemical Company, Limited
    Inventor: Koji Hagiya
  • Publication number: 20120021904
    Abstract: A description is given of (4-haloalkyl-3-thiobenzoyl)cyclohexanediones of the formula (I) and of their use as herbicides. In this formula (I), X, Y, R1, R2, R3, and R4 are radicals such as hydrogen and organic radicals such as alkyl. A and Z are oxygen or alkylene.
    Type: Application
    Filed: July 20, 2011
    Publication date: January 26, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Hartmut AHRENS, Dieter FEUCHT, Elmar GATZWEILER, Isolde HAUSER-HAHN, Christopher Hugh ROSINGER
  • Patent number: 8084649
    Abstract: Cyclohexanedione compounds, and derivatives thereof, which are substituted in 5-position, are suitable for use as herbicides. The cyclohexanedione compounds and derivatives of the invention are compounds of formula (I) wherein the substituents are as defined in the description.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: December 27, 2011
    Assignee: Syngenta Crop Protection, inc.
    Inventors: Michel Muehlebach, William Lutz, Jean Wenger, John Finney, Christopher John Mathews, Delphine Raymonde Suzanne Fawke
  • Publication number: 20110130593
    Abstract: The present invention is directed towards a new class of semi-conducting nonacene derivatives. These compounds are all soluble species and they all possess superior resistance to oxidation as compared to their counterparts that lack the substitution patterns disclosed herein.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 2, 2011
    Inventors: Glen P. Miller, Irvinder Kaur
  • Publication number: 20110130482
    Abstract: The invention provides a process for synthesizing aromatic thioether ketones comprising reacting an aromatic thioether with an acylating agent in the presence of heteropoly acids or heteropoly acid-containing solid supports or the salts of heteropoly acids.
    Type: Application
    Filed: September 19, 2005
    Publication date: June 2, 2011
    Inventors: Roger Prétôr, Paul Adriaan Der Schaaf, Rolf Kugler, Walter Wolf
  • Publication number: 20100297541
    Abstract: Compounds of the formula (I), wherein X is a single bond, CRaRbO, S, NRc or NCORc; Z is formula (II) or C3-C20heteroaryl; L, L1, L2, L3, L4, L5, L6, L7 and L8 for example independently of one another are hydrogen or an organic substituent; Ra, Rb and Rc independently of one another are hydrogen or an organic substituent; R is for example is C5-C20heteroaryl or C6-C14 aryl; and Y is an inorganic or organic anion; are suitable as photolatent acid generators.
    Type: Application
    Filed: September 29, 2008
    Publication date: November 25, 2010
    Applicant: BASF SE
    Inventors: Pascal Hayoz, Hitoshi Yamato, Toshikage Asakura
  • Publication number: 20100227935
    Abstract: The present invention relates to a new class of terpene-derived compounds having an antibiotic activity and of the formulae (I) or (II) in which A is selected from NR1, O, S, CR2R3 or R—(CH2)n—R?, wherein R and R? represent independently NH, O, S or CH2, and in which R1, R2 et R3 are substituents and n is higher than or equal to 1, in particular equal to 2. The invention relates to the compound according to both the formula (I) or the formula (II) taken individually, to mixtures of the two compounds, and to compositions, mainly therapeutic ones, comprising at least one of the compounds or said mixture. According to a particular embodiment, the compound ((I) or (II) taken individually, the mixtures of both compounds and the compositions of the invention are used in the treatment of difficult C-related digestive infections. In one particular embodiment, the compound of the formula (I) is margaucine, a compound produced by a bacterial stem.
    Type: Application
    Filed: September 21, 2007
    Publication date: September 9, 2010
    Applicants: Centre National De La Recherche Scientifique, Universite De Provence-Aix-Marseille 1, Universite Paul Cezanne-Aix-Marseille 3
    Inventors: Jean-Paul Leonetti, Maxime Gualtieri, Laurence Coulibeuf, Gaëtan Herbette
  • Publication number: 20100201019
    Abstract: Waste reduction, including hazardous waste reduction in photoimaging processes can be accomplished by improving diffusional resolution of cationic curable compositions. The addition of fluorinated polymers including fluorinated surfactants provides improved diffusional resolution in cationic and/or radical based photoimaging formulations allowing for image accuracy improvements, and reduced product and process waste quantity and disposal cost. These fluorinated surfactants also allow for increased cure speed, and non-hazardous constituent formulations that result in less wasted material and time.
    Type: Application
    Filed: January 28, 2010
    Publication date: August 12, 2010
    Inventors: John Lawton, Jigeng Xu, John Southwell, Gordon Smith, Willem D. Weenink
  • Patent number: 7759399
    Abstract: A compound comprising a cyclopentanone, cyclopentenone, cyclohexanone or cyclohexenone group, wherein a first ring carbon atom carries an —SR substituent, R is a substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl, or aralkynyl group that, optionally, includes at least one heteroatom in its carbon skeleton, the remaining available ring carbon atoms are optionally substituted, and said compound either: —(a) is more soluble in water at a temperature of 20-40° C.; (b) is less lipophilic; and/or, (c) has a greater therapeutic index; or; (d) is less soluble in water at a temperature of 20-40° C.; (e) is more lipophilic; and/or, (f) has a greater therapeutic index; than an equivalent cyclohex-2-en-1-one or cyclopent-2-en-1-one derivative in which a hydrogen atom replaces said —SR group.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: July 20, 2010
    Assignee: Crawford Healthcare Holdings Limited
    Inventors: Stanley Michael Roberts, Maria Gabriella Santoro, Vasudev Jadhav, Alan Michael Happe, Paul Evans, Nicolette Christa Ross, Timothy James Snape
  • Publication number: 20100173774
    Abstract: Cyclohexanedione compounds, and derivatives thereof, which are substituted in 5-position, are suitable for use as herbicides.
    Type: Application
    Filed: March 7, 2008
    Publication date: July 8, 2010
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Michel Muehlebach, William Lutz, Jean Wenger, John Finney, Christopher John Matthews, Delphine Fawke
  • Publication number: 20100160434
    Abstract: There is provided an organic sulfur compound having an excellent controlling effect on harmful arthropods represented by the formula (I): wherein, R1 represents a C3-C10 alkenyl group optionally substituted with at least one halogen atom, a C3-C10 alkynyl group optionally substituted with at least one halogen atom, or the like, R2 represents a cyano group or the like, R3 represents a hydrogen atom, a halogen atom or a C1-C4 alkyl group, R4 represents a C1-C5 fluoroalkyl group, and n represents 0, 1 or 2.
    Type: Application
    Filed: May 16, 2008
    Publication date: June 24, 2010
    Inventor: Hiroyuki Miyazaki
  • Patent number: 7705065
    Abstract: A photoinitiator compound is functionalized with alkoxy groups so as to be soluble in alkoxy-containing monomers. The photoinitiator has a formula of R1—(OR2)n—OC(?O)—R3, wherein R1—(OR2)n— represents an alkoxy group and R3 represents a photoinitiator structure. The photoinitiator may be used in a composition for incorporation into inks.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: April 27, 2010
    Assignee: Xerox Corporation
    Inventor: Jennifer L. Belelie
  • Publication number: 20100028368
    Abstract: Compounds useful as antiproliferative agents according to formula (I): wherein Ar1, Ar2, Ar3, m and n are as defined herein, salts, antibody conjugates, pharmaceutical compositions, methods of treatment, and synthetic methods are provided.
    Type: Application
    Filed: December 12, 2007
    Publication date: February 4, 2010
    Applicant: TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: E. Premkumar Reddy, M.V. Ramana Reddy
  • Patent number: 7582653
    Abstract: Novel mercaptophenyl naphthyl methane compounds, their pharmaceutically acceptable salts and compositions comprised thereof are useful for the prevention or treatment of various medical indications associated with estrogen dependent diseases or syndromes related to osteoporosis, bone loss, bone formation, cardiovascular disorders, neurodegenerative disorders, menopausal disorders, physiological disorders, diabetes disorders, prostatic carcinoma, cancer of breast, cancer of uterus, cancer of the cervix and cancer of the colon, threatened or habitual abortion, obesity, ovarian development or function, post-partum lactation and depression.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: September 1, 2009
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sangita, Atul Kumar, Man Mohan Singh, Girish Kumar Jain, Puvvada Sri Ramanchandra Murthy, Suprabhat Ray
  • Publication number: 20090197987
    Abstract: Compounds of the formula (I), L, L?, L?, L1, L?1, L?1, L2, L?2, L?2, L3, L?3, L?3, L4, L?4, L?4, L5, L?5, L?5, L6, L?6, L?6, L7, L?7, L?7, L8, L?8 and L?8 independently of one another are hydrogen or an organic substituent; and/or one or more of the pairs L3 and L5, L?3 and L?5 or L?3 and L?5 together denote a single bond, provided that the respective X, X? or X? is not a single bond; and/or L3 and L5, L?3 and L?5 or L?3 and L?5 together denote an organic linking group; and/or one or more of the pairs L1 and L3, L1 and L, L5 and L7, L?1 and L?3, L?1 and L?, L?5 and L?7, L?1 and L?3, L?1 and L?, or L?5 and L?7, together denote an organic linking group; provided that at least one of L, L?, L?, L1, L?1, L?1, L2, L?2, L?2, L3, L?3, L?3, L4, L?4, L?4, L5, L?5, L?5, L6, L?6, L?6, L7, L?7, L?7, L8, L?8 and L?8 is other than hydrogen; X, X? and X? independently of one another are a single bond, CRaRb O, S, NRc or NCORc; Ra, Rb and Rc independently of one another are hydrogen or an organic substituent; and Y is an ino
    Type: Application
    Filed: April 4, 2007
    Publication date: August 6, 2009
    Inventors: Pascal Hayoz, Stephan Ilg
  • Patent number: 7510822
    Abstract: A stimulation sensitive composition comprising: (A) a compound represented by the specific formula which is capable of generating an acid or a radical by stimulation from the external.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: March 31, 2009
    Assignee: FUJIFILM Corporation
    Inventor: Kunihiko Kodama
  • Patent number: 7504542
    Abstract: The present invention relates to the preparation of ?-hydroxy ketones of the general formula I. In particular, the invention relates to novel imidazolinium carboxylate adducts and to a novel process for using catalytic amounts of imidazolium and imidazolinium carboxylate adducts in the acyloin reaction of aldehydes to prepare hydroxy ketones of the general formula I, where R and R? are the same or different and are each H or a straight-chain or branched and optionally substituted C1-C12-alkyl radical, and R??H3CSCH2CH2, t-butyl, n-butyl, sec-butyl, n-propyl, i-propyl, an optionally heteroatom-substituted C6-C18-aryl, heteroaryl, C6-C18-arylalkyl, especially phenylmethyl, where phenyl may again be heteroatom-substituted, or heteroalkyl.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: March 17, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Ralf Jackstell, Irina Jovel, Matthias Beller, Martin Hateley, Christoph Weckbecker, Klaus Huthmacher
  • Publication number: 20090062285
    Abstract: The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.
    Type: Application
    Filed: July 14, 2008
    Publication date: March 5, 2009
    Applicant: National Sun Yat-Sen University
    Inventors: Jyh-Horng Sheu, Chih-Hua Chao, Zhi-Hong Wen
  • Patent number: 7387865
    Abstract: A composition containing a photoacid generator monomer and surfactant, and a method for synthesizing a compound on a substrate using the composition are provided. The method includes bonding a layer of first molecules having an acid labile protecting group to a solid substrate; coating a layer of the photoacid generator monomer composition according to the present invention on the layer of first molecules; exposing the composition layer to light and then heat-treating to remove the acid labile protecting group from the first molecules corresponding to the exposed portion; washing and removing the composition layer from the exposed and unexposed portions; and bonding second molecules to the exposed first molecules.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: June 17, 2008
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sung-ouk Jung, Seung-ju Seo, Jae-chan Park
  • Patent number: 7332631
    Abstract: The present invention provides compounds capable of binding to an Fc receptor and modulating Fc receptor activity comprising a core lipophilic group in the form of an Aryl ring substituted with a group rich in p-electrons. The invention further provides for a method of treating an autoimmune disease involving Fc receptor activity using such compounds. A method for obtaining a compound which modulates Fc receptor activity is also provided, the method comprising: (a) providing or designing compounds having structural characteristics to fit in the groove of the Fc?RIIa structure; and (b) screening the compounds for modulating activity on the Fc receptor.
    Type: Grant
    Filed: December 24, 2003
    Date of Patent: February 19, 2008
    Assignee: Trillium Therapeutics Inc.
    Inventors: Mark Phillip Hogarth, Geoffrey Allan Pietersz, Gerard Peter Moloney
  • Patent number: 7300747
    Abstract: The photobase generator of the invention is represented by the following formula 1: wherein Ar, R, A+ and X? are as defined in the specification. Since the photobase generator of the formula 1 absorbs ultraviolet lights of relatively long wavelength and is photolyzed to generate a strong base efficiently, a composition containing the photobase generator and an episulfide compound is easily cured by polymerization under ultraviolet irradiation.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: November 27, 2007
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hitoshi Okazaki, Junya Hayakawa, Motoharu Takeuchi, Masahiro Jono, Kenji Ishii
  • Patent number: 7214831
    Abstract: Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, for example, an alpha-chalcogenmethylcarbonyl group, such as an alpha-ketothio group, can inhibit histone deacetylase. Histone deacetylase inhibition can repress gene expression, including expression of genes related to tumor suppression. Accordingly, inhibition of histone deacetylase can provide an alternate route for treating cancer, hematological disorders, e.g., hemoglobinopathies, autosomal dominant disorders, e.g. spinal muscular atrophy and Huntington's disease, genetic related metabolic disorders, e.g., cystic fibrosis and adrenoleukodystrophy, or for stimulating hematopoietic cells ex vivo.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: May 8, 2007
    Assignee: Errant Gene Therapeutics, LLC
    Inventors: Hsuan-Yin Lan-Hargest, Robert J. Kaufman
  • Patent number: 7196229
    Abstract: The invention relates to benzoylcyclohexenone derivatives of general formula (I) wherein the variables R1 to R10 and n have the designation cited in claim 1.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: March 27, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang von Deyn, Ernst Baumann, Michael Hofmann, Markus Kordes, Ulf Misslitz, Liliana Parra Rapado, Cyrill Zagar, Matthias Witschel, Andreas Landes
  • Patent number: 7153813
    Abstract: The invention relates to novel substituted aryl ketones of the formula (I) in which Z, X, R and n are as defined in the disclosure, to processes for their preparation and to their use as crop treatment agents, and to intermediates for preparing compounds of the formula (I).
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: December 26, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Georg Schwarz, Mark Wilhelm Drewes, Peter Dahmen, Dieter Feucht, Rolf Pontzen, Monika Schmitt
  • Patent number: 7154007
    Abstract: This invention provides: a compound represented by formula (I): R—Y—(—X-Phe-COCH2COCnF2n+1)m ??(I) wherein R denotes hydrogen, alkyl, phenyl, or a group capable of binding to a protein, peptide, amino acid, nucleic acid, or nucleotide; Y denotes CH2, a carbocyclic ring, or a heterocyclic ring; X denotes O, S, NH, CH2, OCH2, CONH, or NHCO; Phe denotes phenylene; n is an integer between 1 and 5; and m is 1, 2, or 3. This inventions also provides a luminous complex of such compound and a rare earth ion, a labeling reagent comprising such compound or luminous complex, and a process for labeling a protein, peptide, amino acid, nucleic acid, or nucleotide using such labeling reagent.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: December 26, 2006
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Michihiro Saito, Ernoe Pretsch
  • Patent number: 7026372
    Abstract: A composition containing 3,3?-thiobis(propane-1,2-dithiol) and one or more enic compounds which composition is photocurable and can give a cured product having a high refractive index and adequate hardness.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: April 11, 2006
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Kenji Ishii, Hitoshi Okazaki, Mitsuteru Kondo, Masaaki Takasuka, Motoharu Takeuchi
  • Patent number: 7012159
    Abstract: Phenolic compounds of general formula (I); and recording materials characterized by containing one of them and exhibiting high light stability wherein R1 and R2 are each hydrogen or C1-C6 alkyl; m is an integer of 1 to 6; n is an integer of 0 to 2; p and t are each an integer of 0 to 3 with the proviso that not both are simultaneously 0; R3 and R4 are each nitro, carboxyl, halogeno, C1-C6 alkyl, or the like; q and u are each an integer of 0 to 2 with the proviso that when q or u is 2, R3s or R4s may be different from each other; and Y is CO or NR5CO (wherein R5 is hydrogen or the like), with the proviso that when Y is CO, p is 1 and that when p is 0 and Y is NR5CO, n is not 0.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: March 14, 2006
    Assignee: Nippon Soda Co., Ltd.
    Inventors: Tomoya Hidaka, Shinichi Sato, Tadashi Kawakami
  • Patent number: 6924391
    Abstract: Inhibitors of the cytosolic phospholypase A2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula wherein X, Z, X1, R1, R2, Ra, Rb, R3, R4 and Y are as defined in the specification.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: August 2, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jacques Banville, Roger Remillard, Neelakantan Balasubramanian, Gilles Bouthillier, Alain Martel
  • Patent number: 6906076
    Abstract: The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into the nucleus of a cell. The invention encompasses methods of use of such compounds for treatment or prevention of infectious diseases, such as parasitic and viral diseases, including, for example, malaria and acquired immunodeficiency syndrome. The use of the compounds to detect certain specific protein structures which are present in nuclear localization sequences is also taught.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: June 14, 2005
    Assignee: Cytokine Pharmasciences, Inc.
    Inventors: Michael I. Bukrinsky, Anthony Cerami, Peter Ulrich, Bradley Berger
  • Patent number: 6815563
    Abstract: A process for preparing bicyclic 1,3-diketones of the formula I where R1, R2, R3 and R4 are hydrogen, C1-C4-alkyl, C1-C4-alkoxy-carbonyl, halogen, cyano, nitro, C1-C4-alkylthio, C1-C4-alkylsulfenyl or C1-C4-alkylsulfonyl and Z is C1-C4-alkylene, O, S, N—R5 where R5 is C1-C4-alkyl or C1-C4-alkylcarbonyl, which comprises a) reacting a bicyclic olefin of the formula II with haloform in the presence of a base to give the ring-expanded product of the formula III  where R1-R4 and Z are as defined above and X is halogen; b) hydrolyzing the allylic halogen of the compound of the formula III to the allyl alcohol of the formula IV c) oxidizing the allyl alcohol of the formula IV to the unsaturated ketone of the formula V d) reacting the ketone of the formula V with a nucleophilic ion Y− which stabilizes a negative charge to give the ketone of the formula VI e) hydrolyzing the ketone of the formula VI to th
    Type: Grant
    Filed: January 6, 2003
    Date of Patent: November 9, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Klaus Langemann, Ulf Misslitz, Ernst Baumann, Wolfgang von Deyn, Steffen Kudis, Thorsten Volk, Guido Mayer
  • Patent number: 6638685
    Abstract: A chemically amplified photo-resist contains a photoacid generator for changing the solubility of resin after exposure to 130-220 nanometer wavelength light, and the photoacid generator contains two kinds of sulfonium salt compound expressed by general formulae [1] and [2] so that the chemically amplified photo-resist is improved in resolution, sensitivity and smoothness on side surfaces of a transferred pattern.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: October 28, 2003
    Assignee: NEC Corporation
    Inventors: Katsumi Maeda, Shigeyuki Iwasa, Kaichiro Nakano, Etsuo Hasegawa
  • Patent number: 6599861
    Abstract: Compounds of formula I wherein the substituents are defined as in claim 1, as well as the agronomically acceptable salts, isomers and enantiomers of these compounds, as well as the agronomically acceptable salts/N-oxides/isomers/enantiomers of these compounds, are eminently suitable for use as herbicides.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: July 29, 2003
    Assignee: Syngenta Participations AG
    Inventors: Jürgen Schaetzer, Alain De Mesmaeker, Shy-Fuh Lee
  • Publication number: 20030060651
    Abstract: Benzoylcyclohexanedione derivatives of the formula (I) and their use as herbicides are described.
    Type: Application
    Filed: April 4, 2002
    Publication date: March 27, 2003
    Inventors: Thomas Seitz, Andreas van Almsick, Lothar Willms, Thomas Auler, Herman Bieringer, Hubert Menne
  • Publication number: 20030060666
    Abstract: A process for preparing an &agr;-haloketone of the formula (1) 1
    Type: Application
    Filed: September 3, 2002
    Publication date: March 27, 2003
    Inventors: Dieter Heldmann, Juergen Stohrer
  • Patent number: 6525225
    Abstract: A process for preparing compounds of the formula: wherein R2 is lower alkyl; or phenyl optionally substituted by from one to five groups, the same or different, which are lower alkyl, lower haloalkyl, halogen or —SR4; R3 is halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, —S-alkyl, cycloalkyl having from 3 to 7 carbon atoms in the ring, alkenyl or alkynyl having from 3 to 7 carbon atoms, or —(CR5R6)—SR2 wherein q is one or two; R4 is lower alkyl; R5 and R6 independently represent hydrogen, lower alkyl or lower haloalkyl; and n is zero or an integer from one to three; intermediate compounds of the formula: and processes for preparing them.
    Type: Grant
    Filed: November 23, 2001
    Date of Patent: February 25, 2003
    Assignee: Rhone Poulenc Agrochimie
    Inventors: Virginie Pevere, Alain Gadras, Susan Mary Cramp, Charles Walter Ellwood
  • Publication number: 20030012803
    Abstract: The invention relates to novel heteroethynylenic compounds having the general formula (I): 1
    Type: Application
    Filed: July 11, 2002
    Publication date: January 16, 2003
    Inventors: Philippe Diaz, Jean-Michel Bernardon
  • Publication number: 20020182535
    Abstract: A chemically amplified photo-resist contains a photoacid generator for changing the solubility of resin after exposure to 130-220 nanometer wavelength light, and the photoacid generator contains two kinds of sulfonium salt compound expressed by general formulae [1] and [2] 1
    Type: Application
    Filed: November 14, 2001
    Publication date: December 5, 2002
    Inventors: Katsumi Maeda, Shigeyuki Iwasa, Kaichiro Nakano, Etsuo Hasegawa
  • Patent number: 6486356
    Abstract: A process for preparing a compound of the formula: which comprises reacting a compound of the formula: wherein R1 is C1-6 straight- or branched-chain alkyl, with a compound of the formula: in an aprotic solvent in the presence of base.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: November 26, 2002
    Assignee: Rhone-Poulenc Agro
    Inventors: Didier Bernard, Michel Casado, Virginie Pevere, Alain Truchon
  • Publication number: 20020103389
    Abstract: The invention relates to compounds of formula I 1
    Type: Application
    Filed: December 4, 2001
    Publication date: August 1, 2002
    Inventors: Sabine Haag, Herbert Kogler, Ziyu Li, Laszlo Vertesy
  • Publication number: 20020087025
    Abstract: An improved method is described for making 9-deoxy-PGF1-type compounds. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds.
    Type: Application
    Filed: February 15, 2002
    Publication date: July 4, 2002
    Applicant: UNITED THERAPEUTICS CORPORATION
    Inventors: Robert M. Moriarty, Raju Penmasta, Liang Guo, Munagala S. Rao, James P. Staszewski
  • Publication number: 20020062045
    Abstract: A process for preparing compounds of the formula: 1
    Type: Application
    Filed: November 23, 2001
    Publication date: May 23, 2002
    Inventors: Virginie Pevere, Alain Gadras, Susan Mary Cramp, Charles Walter Ellwood
  • Patent number: 6379590
    Abstract: A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D wherein A′ is selected from the group consisting of —Br, —Cl, —F, —NO2, and —CN; A is selected from the group consisting of —NO2, —CN, —CO2R, —C(O)R, —SO2R, —SO2RF, —C(CN)═C(CN)2 and —CH═C(CN)2; RF is —CpF2p+1, p=from about 0 to about 10; R is an straight, branched or cyclic aliphatic alkyl group having about 1 to 10 carbon atoms, or an aromatic group such as phenyl or naphthyl; and is a carbonyl or a protected carbonyl such as a ketal or thio-ketal such as wherein R′ is —CrH2r+1; R″ is —(CH2)r—; and r is independently 2 or 3, with a nucleophilic reagent in the presence of an aprotic solvent
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: April 30, 2002
    Assignee: AlliedSignal Inc.
    Inventors: Chengjiu Wu, Jianhui Shan
  • Patent number: 6368769
    Abstract: Novel aromatic sulfonium compounds of general formula (I), photoacid generators comprising the same, and photopolymerizable compositions containing the same, capable of providing stereolithographic resin compositions which do not suffer from the hindrance to curing by oxygen, can easily give shaped articles having desired sizes by virtue of the high accuracy thereof in curing, and can attain a satisfactory curing depth owing to the high sensitivity thereof for radiant energy; and a stereolithographic process.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: April 9, 2002
    Assignee: Asahi Denki Kogyo Kabushiki Kaisha
    Inventors: Kazuo Ohkawa, Hiroyuki Tachikawa, Satoyuki Chikaoka
  • Patent number: 6294698
    Abstract: The present invention is directed to new, energy-efficient photoinitiators in the form of organic sulfur-containing compounds. The present invention is also directed to a method of generating reactive species which includes exposing one or more photoinitiators to radiation to form one or more reactive species. Also described are methods of polymerizing unsaturated monomers, methods of curing an unsaturated oligomer/monomer mixture, and methods of laminating using the photoinitiators of the present invention.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: September 25, 2001
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Ronald S. Nohr, J. Gavin MacDonald
  • Patent number: 6288063
    Abstract: Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula (T)xA—B—D—E—G wherein A is an aryl or heteroaryl rings; B is an aryl or heteroaryl ring or a bond; each T is a substituent group; x is 0, 1, or 2; the group D represents the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formation, possible structures being shown in the text and claims; and the group G represents and with the proviso that when G is each of the substituents on E is an independent substituent; and include pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: September 11, 2001
    Assignee: Bayer Corporation
    Inventors: Harold Clinton Eugene Kluender, David Ross Brittelli, William Riley Schoen, Sookhee Nicole Ha