Polyoxy Patents (Class 568/648)
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Patent number: 9963557Abstract: A coalescent consisting essentially of a residue from a process for forming propyleneglycol phenyl ether, the coalescent consisting essentially of 65%-75% by weight, based on the weight of the residue, dipropyleneglycol phenyl ether, 8%-10% by weight, based on the weight of the coalescent, monopropyleneglycol phenyl ether, 4%-6% by weight, based on the weight of the coalescent, tripropyleneglycol phenyl ether, and 0.1%-10% by weight, based on the weight of the coalescent, alkalinity (reported as NaOH) is provided. Also provided is a method for forming certain low-VOC, low cost, coalesced aqueous polymeric dispersions including, as copolymerized units, from 70% to 100% by weight, based on the solids weight of the aqueous polymeric dispersion, vinyl acetate monomer and an aqueous coating composition including the coalesced aqueous polymeric dispersion.Type: GrantFiled: May 9, 2016Date of Patent: May 8, 2018Assignees: Dow Global Technologies LLC, Rohm and Haas CompanyInventors: Thomas Glenn Madle, Sudhakar Balijepalli, Alvin M. Maurice, Felipe A. Donate
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Patent number: 9631205Abstract: A process for producing a cross-linked crystallized protein complex, which comprises: a first step of concentrating a crude protein derived from an animal or plant; a second step of encapsulating the protein in a gel, to thereby allow the protein to undergo air oxidation, and then extracting a protein complex from the gel; a third step of allowing the extracted protein complex to undergo crystallization and precipitation; and a fourth step of cross-linking the precipitated protein complex. Alternatively, by use of a fifth step of drying (FD) the obtained crosslinked crystallized protein complex, to thereby form a powder. As a result, there is provided an enzyme which is stable at room temperature storage, and has an activity in catalyzing an asymmetric oxidation reaction. That is, there is provided a useful material which enables an efficient enzyme-mimetic reaction under a mild condition.Type: GrantFiled: July 10, 2013Date of Patent: April 25, 2017Assignee: Sanyo Foods Co., Ltd.Inventor: Hiroyuki Nagaoka
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Patent number: 9556457Abstract: A process for producing a cross-linked crystallized protein complex, which comprises: a first step of concentrating a crude protein derived from an animal or plant; a second step of encapsulating the protein in a gel, to thereby allow the protein to undergo air oxidation, and then extracting a protein complex from the gel; a third step of allowing the extracted protein complex to undergo crystallization and precipitation; and a fourth step of cross-linking the precipitated protein complex. Alternatively, by use of a fifth step of drying (FD) the obtained crosslinked crystallized protein complex, to thereby form a powder. As a result, there is provided an enzyme which is stable at room temperature storage, and has an activity in catalyzing an asymmetric oxidation reaction. That is, there is provided a useful material which enables an efficient enzyme-mimetic reaction under a mild condition.Type: GrantFiled: July 10, 2013Date of Patent: January 31, 2017Assignee: SANYO FOODS CO., LTD.Inventor: Hiroyuki Nagaoka
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Publication number: 20150099893Abstract: A reagent that enhances acid generation of a photoacid generator and composition containing such a reagent is described.Type: ApplicationFiled: October 7, 2014Publication date: April 9, 2015Inventor: Satoshi ENOMOTO
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Publication number: 20150060728Abstract: Described is a reagent that enhances acid generation of a photoacid generator and a composition containing such a reagent.Type: ApplicationFiled: September 3, 2014Publication date: March 5, 2015Inventors: Satoshi Enomoto, Takashi Miyazawa
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Publication number: 20150031920Abstract: [Object] The object of this invention is to provide a method for producing an optically active secondary alcohol at a high optical purity by hydrogenating a substrate carbonyl compound at a high efficiency using as a catalyst a ruthenium complex bearing as a ligand certain optically active diphosphine compound and a readily synthesized amine compound.Type: ApplicationFiled: July 25, 2014Publication date: January 29, 2015Inventors: TAKEAKI KATAYAMA, KUNIHIKO TSUTSUMI, KUNIHIKO MURATA, TAKESHI OHKUMA, NORIYOSHI ARAI
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Patent number: 8936659Abstract: A substance includes diamond particles having a maximum linear dimension of less than about 1 ?m and an organic compound attached to surfaces of the diamond particles. The organic compound may include a surfactant or a polymer. A method of forming a substance includes exposing diamond particles to an organic compound, and exposing the diamond particles in the presence of the organic compound to ultrasonic energy. The diamond particles may have a maximum linear dimension of less than about 1 ?m. A composition includes a liquid, a plurality of diamond nanoparticles dispersed within the liquid, and an organic compound attached to surfaces of the diamond nanoparticles. A method includes mixing a plurality of diamond particles with a solution comprising a liquid solvent and an organic compound, and exposing the mixture including the plurality of diamond nanoparticles and the solution to ultrasonic energy.Type: GrantFiled: October 18, 2011Date of Patent: January 20, 2015Assignee: Baker Hughes IncorporatedInventors: Soma Chakraborty, Gaurav Agrawal, Anthony A. DiGiovanni
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Patent number: 8921611Abstract: The invention provides a method for preparing 1,4-di-tert-butyl-2,5-bis(2-methoxyethoxy)benzene, the method comprising reacting 2,5-di-tert-butylbenzene-1,4-diol with cesium carbonate and halogenated ether in dimethyl formamide. The method yields 500 gram batches at a time, or multiples thereof. The method enables the industrial production of redox shuttles for use in lithium ion battery systems.Type: GrantFiled: April 13, 2012Date of Patent: December 30, 2014Assignee: Uchicago Argonne, LLCInventors: Krzysztof Z. Pupek, Trevor L. Dzwiniel, Gregory K. Krumdick
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Patent number: 8901323Abstract: Provided is a ruthenium complex that is represented by general formula (1*) and is useful as an asymmetric reduction catalyst. (In the formula, * is an asymmetric carbon atom; R1 is an arenesulfonyl group, and the like; R2 and R3 are a phenyl group, and the like; R10 through R14 are selected from a hydrogen atom, C1-10 alkyl group, and the like, but R10 through R14 are not simultaneously hydrogen atoms; X is a halogen atom and the like; j and k are each either 0 or 1; and j+k is 0 or 2.Type: GrantFiled: May 2, 2012Date of Patent: December 2, 2014Assignee: Takasago International CorporationInventors: Taichiro Touge, Tomohiko Hakamata, Hideki Nara
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Publication number: 20140296343Abstract: Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule.Type: ApplicationFiled: March 31, 2014Publication date: October 2, 2014Inventors: Frank M. LONGO, Stephen M. MASSA, Sandeep GUPTA
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Publication number: 20140255793Abstract: Functional electrolyte solvents include compounds having at least one aromatic ring with 2, 3, 4 or 5 substituents, at least one of which is a substituted or unsubstituted methoxy group, at least one of which is a tert-butyl group and at least one of which is a substituted or unsubstituted polyether or poly(ethylene oxide) (PEO) group bonded through oxygen to the aromatic ring, are provided.Type: ApplicationFiled: March 6, 2013Publication date: September 11, 2014Applicant: UCHICAGO ARGONNE, LLCInventors: Lu Zhang, Zhengcheng Zhang, Khalil Amine
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Publication number: 20140179923Abstract: A new class of ligands derived from benzo[h]quinoline are described and these ligands are used to prepare several novel transition metal complexes. The complexes are preferably of the group VIII transition metals iron, ruthenium or osmium, with the benzo[h]quinoline ligands acting as tridentate ligands. The complexes described are proved to be very active catalysts for the reduction of ketones and aldehydes to alcohols, via hydrogen transfer and hydrogenation reactions. These compounds hence can be usefully employed as catalysts in said reduction reactions.Type: ApplicationFiled: November 19, 2013Publication date: June 26, 2014Applicant: UNIVERSITA' DEGLI STUDI DI UDINEInventors: Pierluigi Rigo, Walter Baratta, Katia Siega, Giorgio Adolfo Chelucci, Maurizio Ballico, Santo Magnolia
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Publication number: 20140051871Abstract: Provided is a ruthenium complex that is represented by general formula (1*) and is useful as an asymmetric reduction catalyst. (In the formula, * is an asymmetric carbon atom; R1 is an arenesulfonyl group, and the like; R2 and R3 are a phenyl group, and the like; R10 through R14 are selected from a hydrogen atom, C1-10 alkyl group, and the like, but R10 through R14 are not simultaneously hydrogen atoms; X is a halogen atom and the like; j and k are each either 0 or 1; and j+k is 0 or 2.Type: ApplicationFiled: May 2, 2012Publication date: February 20, 2014Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventors: Taichiro Touge, Tomohiko Hakamata, Hideki Nara
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Publication number: 20140046074Abstract: The present invention relates to a (2R, 3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.Type: ApplicationFiled: January 31, 2012Publication date: February 13, 2014Inventors: Qiang Zhang, Rongxia Zhang, Guanghui Tian, Jianfeng Li, Fuqiang Zhu, Xiangrui Jiang, Jingshan Shen
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Patent number: 8618337Abstract: The invention relates to a process for preparing polyether alcohols by reacting a) aromatic amines with b) alkylene oxides in the presence of c) a catalyst, wherein the alkylene oxide b) comprises at least 90% by weight, based on the weight of the component b), of propylene oxide and an amine is used as catalyst c).Type: GrantFiled: April 22, 2011Date of Patent: December 31, 2013Assignee: BASF SEInventors: Sirus Zarbakhsh, Markus Schuette, Marc Fricke
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Patent number: 8558029Abstract: Phenolic glycol ethers, e.g., ethylene glycol phenyl ether, are prepared by a continuous, nonaqueous process comprising the steps of (A) contacting under isothermal reactive conditions in a first reactor or reaction zone an alkylene oxide, e.g., ethylene oxide, with (i) a stoichiometric molar excess of a phenolic compound, e.g., phenol, and (ii) a catalytic amount of a base, e.g., sodium hydroxide, homogeneously dispersed throughout the phenolic compound, to form a first intermediate phenolic glycol ether product, (Bj transferring the first intermediate phenolic glycol ether product to a second reactor or reaction zone, and (C) subjecting the first intermediate phenolic glycol ether product to adiabatic reactive conditions in the second reactor or reaction zone to form a second intermediate phenolic glycol ether product comprising phenolic glycol ether, unreacted phenolic compound, catalyst, water and byproduct glycols.Type: GrantFiled: December 8, 2008Date of Patent: October 15, 2013Assignee: Dow Global Technologies LLCInventors: Max Tirtowidjojo, Edward D. Daugs
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Publication number: 20130225822Abstract: The present invention relates to a chiral spiro-pyridylamidophosphine ligand compound, synthesis method therefor and application thereof. The chiral spiro-pyridylamidophosphine compound is a compound having a structure of Formula (I), a racemate or optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly characterized by having a chiral spiro-dihydro-indene skeleton in its structure. The chiral spiro-pyridylamidophosphine compound may be synthesized with optical active 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene or substituted 7-diaryl/alkylphosphino-7?-amino-1,1?-spiro-dihydro-indene having a spiro-skeleton as chiral starting material. The chiral spiro-pyridylamidophosphine compound may be used as a chiral ligand in asymmetric hydrogenation of a carbonyl compound catalyzed by iridium, in which the reaction activity is very high, the amount of the catalyst may be 0.0001 mol %, and the enantioselectivity of the reaction is up to 99.9% ee.Type: ApplicationFiled: November 18, 2011Publication date: August 29, 2013Inventors: Qilin Zhou, Jianhua Xie, Xiaoyan Liu, Jianbo Xie, Lixin Wang
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Publication number: 20130220159Abstract: An offset printing blanket cleaning liquid includes: a solvent having a dipole moment of about 1.7 or more but less than about 4.1 and having a ? covalent bond in a molecular skeleton thereof. Moreover, an ink composition includes: an organic material; and a solvent having a dipole moment of about 1.3 to about 3.0 both inclusive and having a ? covalent bond in a molecular skeleton thereof.Type: ApplicationFiled: February 19, 2013Publication date: August 29, 2013Applicant: SONY CORPORATIONInventor: SONY CORPORATION
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Publication number: 20130217899Abstract: The present invention relates to processes for the preparation of (2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride (Fingolimod) and pharmaceutically acceptable salts thereof, and intermediates formed in such processes.Type: ApplicationFiled: October 27, 2011Publication date: August 22, 2013Applicant: MAPI PHARMA LTD.Inventors: Ehud Marom, Michael Mizhiritskii, Shai Rubnov
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Patent number: 8471048Abstract: The present invention relates to a ruthenium carbonyl complex that is represented by the following Formula (1): RuXY(CO)(L)??(1) (in the Formula (1), X and Y, which may be the same or different from each other, represent an anionic ligand and L represents a tridentate aminodiphosphine ligand which has two phosphino groups and a —NH— group), its production method, and a method for production of alcohols by hydrogenation-reduction of ketones, esters, and lactones using the complex as a catalyst. The ruthenium carbonyl complex of the invention has a high catalytic activity and it can be easily prepared and handled.Type: GrantFiled: June 30, 2010Date of Patent: June 25, 2013Assignee: Takasago International CorporationInventors: Wataru Kuriyama, Takaji Matsumoto, Yasunori Ino, Osamu Ogata
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Publication number: 20130158276Abstract: Provided is a catalyst for asymmetric reduction, which can be produced by a convenient and safe production method, has a strong catalytic activity, and has excellent stereoselectivity. The present invention relates to a ruthenium complex represented by the following formula (1): wherein R1 represents an alkyl group or the like; Y represents a hydrogen atom; X represents a halogen atom or the like; j and k each represent 0 or 1; R2 and R3 each represent an alkyl group or the like; R11 to R19 each represent a hydrogen atom, an alkyl group or the like; Z represents oxygen or sulfur; n1 represents 1 or 2; and n2 represents an integer from 1 to 3, a method for producing the ruthenium complex, a catalyst for asymmetric reduction formed from the ruthenium complex, and methods for selectively producing an optically active alcohol and an optically active amine using the catalyst for asymmetric reduction.Type: ApplicationFiled: June 17, 2011Publication date: June 20, 2013Applicant: TAKASAGO INTERNATIONAL CORPORATIONInventors: Taichiro Touge, Hideki Nara, Tomohiko Hakamada
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Patent number: 8420853Abstract: Disclosed is tonovel cyclic derivatives having potent inhibiting effect on melanin formation and skin hyper-pigmentation activity with no adverse response to skin. They can be used as the therapeutics for treating and preventing the skin disease caused by over-reproduced melanin.Type: GrantFiled: July 2, 2007Date of Patent: April 16, 2013Assignees: Wonkisopharm Co., LtdInventors: Hyunchul Cho, Yonghyun Choi, Jonghan Yhei
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Publication number: 20130053574Abstract: The invention relates to an asymmetric hydrogenation method for ketone compounds, comprising the step of: under hydrogen atmosphere, in the presence of an in situ catalyst derived from a chiral ligand and a ruthenium salt, adding a ketone compound and a base into a second solvent to carry out an asymmetric hydrogenation for the ketone compound. The invention can obtain a conversion of 100% and a highest asymmetric inducement effect of 99.7% for the ketone compound. The invention has the advantages including simple procedure, high conversion and selectivity, good atom economy and good prospect of industrial application.Type: ApplicationFiled: April 16, 2012Publication date: February 28, 2013Applicant: NIPPON CHEMICAL INDUSTRIAL CO., LTD.Inventors: Wanbin Zhang, Delong Liu, Hui Guo, Yangang Liu
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Patent number: 8349924Abstract: The present invention relates to a group of new plasticizers for thermoplastics such as polypropylene, copolymers of polypropylene, polyethylene, polyethylene terephthalates, polystyrene and/or other polymers or mixtures of polymers containing organic and/or inorganic fillers, where the plasticizer is used for obtaining polyvinyl chloride like aspects and improved processability as well as for obtaining a better flexibility and a lower energy consumption during the processing step.Type: GrantFiled: January 15, 2010Date of Patent: January 8, 2013Assignee: JJI Technologies, LLCInventors: Anton Constantinescu, Jose Reyes
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Publication number: 20120302796Abstract: The invention provides for a process for the depolymerization of lignin in an inert atmosphere to result in substituted phenolic monomer compounds. The process is catalysed by heterogeneous solid acid catalysts and is carried out in batch or continuous mode.Type: ApplicationFiled: May 9, 2012Publication date: November 29, 2012Inventors: Paresh Laxmikant DHEPE, Deepa Ayillath Kutteri
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Patent number: 8293948Abstract: A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.Type: GrantFiled: January 9, 2012Date of Patent: October 23, 2012Assignee: Jitsubo Co., Ltd.Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
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Publication number: 20120130133Abstract: Processes for preparing vitamin D2 derivatives and intermediates to vitamin D2 derivatives are disclosed. An improved photolysis process for the preparation of cis intermediate (I) from the trans starting material (II) are disclosed. Also disclosed is an improved process for the formation of a trans double bond at C22-C23 of the vitamin D2 derivative, which provides high selectivity of the desired trans double bond of compound (III) over the undesired cis double bond of compound (IIIA).Type: ApplicationFiled: November 25, 2009Publication date: May 24, 2012Applicant: CYTOCHROMA INC.Inventor: Uttam Saha
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Publication number: 20120059149Abstract: [Summary] [Problem] Provision of a novel compound which is easily-soluble in isopropyl acetate superior in liquid-separation operability, and can be used for a production method of peptide and the like, that provides a final product simply by extraction-layer-separating, without crystallization and isolation of each intermediate in each step. [Solving Means] It has been found that the above-mentioned problems can be solved by a particular branched chain-containing aromatic compound.Type: ApplicationFiled: August 30, 2011Publication date: March 8, 2012Applicant: AJINOMOTO CO. INC.Inventor: Daisuke TAKAHASHI
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Publication number: 20120034464Abstract: A substance includes diamond particles having a maximum linear dimension of less than about 1 ?m and an organic compound attached to surfaces of the diamond particles. The organic compound may include a surfactant or a polymer. A method of forming a substance includes exposing diamond particles to an organic compound, and exposing the diamond particles in the presence of the organic compound to ultrasonic energy. The diamond particles may have a maximum linear dimension of less than about 1 ?m. A composition includes a liquid, a plurality of diamond nanoparticles dispersed within the liquid, and an organic compound attached to surfaces of the diamond nanoparticles. A method includes mixing a plurality of diamond particles with a solution comprising a liquid solvent and an organic compound, and exposing the mixture including the plurality of diamond nanoparticles and the solution to ultrasonic energy.Type: ApplicationFiled: October 18, 2011Publication date: February 9, 2012Applicant: BAKER HUGHES INCORPORATEDInventors: Soma Chakraborty, Gaurav Agrawal, Anthony A. DiGiovanni
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Patent number: 8093435Abstract: A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.Type: GrantFiled: February 19, 2007Date of Patent: January 10, 2012Assignee: JITSUBO Co., Ltd.Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
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Patent number: 8088954Abstract: The invention relates to a compound according to Formula (IX) and salts thereof, wherein R1, R2 and R5 are each independently selected from H and hydrocarbon moieties, which hydrocarbon moieties optionally comprise one or more heteroatoms, and which hydrocarbons optionally comprise substituents, or when the compound according to formula (IX) is a salt, R1 and/or R2 may be a cation, R3, and R4 each independently selected from hydrocarbon moieties, which hydrocarbon moieties optionally comprise one or more heteroatoms, and which hydrocarbons optionally comprise substituents, and wherein any two of R1, R2, R3, R4 and R5 are optionally linked together to form a ring structure. The invention further relates to the preparation of such a compound and to the use of such a compound for preparing a pharmaceutical compound, an agrochemical compound, an intermediate for a pharmaceutical compound or an intermediate for an agrochemical compound.Type: GrantFiled: July 11, 2008Date of Patent: January 3, 2012Assignee: DSM IP Assets B.V.Inventors: Gerardus Karel Maria Verzijl, Henricus Martinus Maria Gerardus Straatman, Andreas Hendrikus Maria De Vries, Lizette Schmieder, Jeroen Antonius Franciscus Boogers
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Publication number: 20110294003Abstract: Compounds may have general Formula I, II, or III: where R1, R2, R3, and R4 are independently H, F, Cl, Br, CN, NO2, a alkyl group, a haloalkyl group, a phosphate group, a polyether group; or R1 and R2, or R3 and R4, or R2 and R3 (in the case of Formula II) may join together to form a fused ring on the benzene ring; and X and Z are independently a group of Formula A: where R5 and R6 and R7 are independently H, F, Cl, Br, CN, NO2, a alkyl group, a haloalkyl group, a phosphate group, or a polyether group; R7 is H, F, Cl, Br, CN, NO2, a alkyl group, a haloalkyl group, a phosphate group, or a polyether group; n is an integer from 1 to 8; and m is an integer from 1 to 13. Such compounds may be used as redox shuttles in electrolytes for use in electrochemical cells, batteries and electronic devices.Type: ApplicationFiled: May 24, 2011Publication date: December 1, 2011Inventors: Zhengcheng Zhang, Lu Zhang, Khalil Amine
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Publication number: 20110251390Abstract: Chiral amino alcohol and amino phosphine compounds are provided herein, which compounds are useful for asymmetric synthesis.Type: ApplicationFiled: October 2, 2009Publication date: October 13, 2011Inventors: Daniel L. Comins, Sonja S. Capracotta
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Publication number: 20110237814Abstract: The present invention relates to a ruthenium carbonyl complex that is represented by the following Formula (1): RuXY(CO)(L)??(1) (in the Formula (1), X and Y, which may be the same or different from each other, represent an anionic ligand and L represents a tridentate aminodiphosphine ligand which has two phosphino groups and a —NH— group), its production method, and a method for production of alcohols by hydrogenation-reduction of ketones, esters, and lactones using the complex as a catalyst. The ruthenium carbonyl complex of the invention has a high catalytic activity and it can be easily prepared and handled.Type: ApplicationFiled: June 30, 2010Publication date: September 29, 2011Applicant: Takasago International CorporationInventors: Wataru Kuriyama, Takaji Matsumoto, Yasunori Ino, Osamu Ogata
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Patent number: 8008531Abstract: A process for benzylating an alcohol includes mixing 2-benzyloxy-1-methylpyridinium triflate in an aromatic hydrocarbon solvent having a predetermined boiling point; adding an acid scavenger to the mixture; combining the alcohol to be benzylated with the mixture; reacting the alcohol with the 2-benzyloxy-1-methylpyridinium triflate by heating above ambient temperature to generate the benzylated alcohol; and separating the benzylated alcohol from the mixture.Type: GrantFiled: June 23, 2010Date of Patent: August 30, 2011Assignee: The Florida State University Research Foundation, Inc.Inventor: Gregory Dudley
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Patent number: 8003828Abstract: The present invention provides a method of producing reduced coenzyme Q10 crystals suitable for commercial scale production thereof. According to a method of the present invention of producing a reduced coenzyme Q10 crystal which comprises a crystallization of reduced coenzyme Q10 in a solution of alcohols and/or ketones, reduced coenzyme Q10 crystal excellent in slurry properties and crystalline properties maybe obtained. Moreover, an isolation process including a crystal separation or the whole process including the isolation process maybe minimized and simplified. Thus, highly pure reduced coenzyme Q10 may be obtained in a high yield.Type: GrantFiled: July 15, 2002Date of Patent: August 23, 2011Assignee: Kaneka CorporationInventors: Takahiro Ueda, Shiro Kitamura, Yasuyoshi Ueda
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Publication number: 20110160433Abstract: The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14.Type: ApplicationFiled: December 22, 2010Publication date: June 30, 2011Applicant: AJINOMOTO CO., INC.Inventor: Daisuke TAKAHASHI
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Publication number: 20110152332Abstract: The present invention relates to novel pesticidal azolidine derivatives as well as to oxazolidinone derivatives and their use as pesticides for combating animal parasites which occur in the agrochemical field and in the field of veterinary medicine, respectively. wherein X, m, R?, Q, G, U, l, A1 to A4 and R are as defined herein.Type: ApplicationFiled: November 1, 2010Publication date: June 23, 2011Applicant: Bayer CropScience AGInventors: Tetsuya Murata, Mamoru Hatazawa, Peter Brüchner, Eiichi Shimojo, Teruyuki Ichihara, Masashi Ataka, Katsuhiko Shibuya, Ulrich Görgens
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Patent number: 7893304Abstract: The present invention provides compounds that are useful for preventing or treating brain dysfunctions, motor dysfunctions, or urinary dysfunctions caused by the degeneration and/or loss of the central nervous system or peripheral nervous system cells.Type: GrantFiled: February 23, 2006Date of Patent: February 22, 2011Assignee: Meiji Dairies CorporationInventors: Bang Luu, Dominique Bagnard, Mazen Hanbali, Masashi Yamada, Hiroto Suzuki
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Publication number: 20110009675Abstract: Phenolic glycol ethers, e.g., ethylene glycol phenyl ether, are prepared by a continuous, nonaqueous process comprising the steps of (A) contacting under isothermal reactive conditions in a first reactor or reaction zone an alkylene oxide, e.g., ethylene oxide, with (i) a stoichiometric molar excess of a phenolic compound, e.g., phenol, and (ii) a catalytic amount of a base, e.g., sodium hydroxide, homogeneously dispersed throughout the phenolic compound, to form a first intermediate phenolic glycol ether product, (Bj transferring the first intermediate phenolic glycol ether product to a second reactor or reaction zone, and (C) subjecting the first intermediate phenolic glycol ether product to adiabatic reactive conditions in the second reactor or reaction zone to form a second intermediate phenolic glycol ether product comprising phenolic glycol ether, unreacted phenolic compound, catalyst, water and byproduct glycols.Type: ApplicationFiled: December 8, 2008Publication date: January 13, 2011Inventors: Max Tirtowidjojo, Edward D. Daugs
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Publication number: 20100324324Abstract: A process for benzylating an alcohol includes mixing 2-benzyloxy-1-methylpyridinium triflate in an aromatic hydrocarbon solvent having a predetermined boiling point; adding an acid scavenger to the mixture; combining the alcohol to be benzylated with the mixture; reacting the alcohol with the 2-benzyloxy-1-methylpyridinium triflate by heating above ambient temperature to generate the benzylated alcohol; and separating the benzylated alcohol from the mixture.Type: ApplicationFiled: June 23, 2010Publication date: December 23, 2010Inventor: Gregory Dudley
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Patent number: 7828991Abstract: This invention relates to novel polyether polyols which are prepared by alkoxylation of renewable resource materials, and particularly cashew nutshell liquid (CNSL), and to a process for the preparation of these novel polyether polyols. This invention also relates to flexible polyurethane foams prepared from these long chain polyether polyols, and to a process for the production of these flexible polyurethane foams.Type: GrantFiled: December 8, 2006Date of Patent: November 9, 2010Assignee: Bayer MaterialScience LLCInventors: Jack R. Reese, Micah N. Moore, Don S. Wardius, Stanley L. Hager
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Publication number: 20100280273Abstract: The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Ru complexes with bidentate ligands, having one amino or imino coordinating group and one phosphino coordinating group, in hydrogenation processes for the reduction of esters or lactones into the corresponding alcohol or diol respectively.Type: ApplicationFiled: July 20, 2010Publication date: November 4, 2010Inventors: Lionel Saudan, Philippe Dupau, Jean-Jacques Riedhauser, Patrick Wyss
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Publication number: 20100267965Abstract: The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula II, or a salt thereof, and a compound of formula VI or a salt thereof, wherein R3 and R4 as well as Act are as defined in the specification, and processes of manufacturing these. Additionally transformation of compounds (VI) with metallo organic compounds (VII) give rise to the new compounds (VIII) which are direct precursors for the preparation of Aliskiren.Type: ApplicationFiled: June 25, 2010Publication date: October 21, 2010Inventors: Gottfried Sedelmeier, Dominique Grimler, Murat Acemoglu
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Publication number: 20100256344Abstract: The present invention relates to various methods of sensitizing and modifying nanosensor platforms. In one embodiment, the present invention provides a method of increasing sensitivity by inhibiting oxidation of one or more 1,4-hydroquinone (HQ) molecules, functionalizing the nanosensor by using one or more diazonium molecules, creating one or more oxidized carbon groups on the nanosensor, and/or depositing one or more metal clusters on the nanosensor.Type: ApplicationFiled: April 2, 2010Publication date: October 7, 2010Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Mark E. Thompson, Chongwu Zhou, Richard J. Cote, Fumiaki Ishikawa, Rui Zhang, Marco Curreli
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Publication number: 20100197972Abstract: The invention relates to a compound according to Formula (IX) and salts thereof, wherein R1, R2 and R5 are each independently selected from H and hydrocarbon moieties, which hydrocarbon moieties optionally comprise one or more heteroatoms, and which hydrocarbons optionally comprise substituents, or when the compound according to formula (IX) is a salt, R1 and/or R2 may be a cation, R3, and R4 each independently selected from hydrocarbon moieties, which hydrocarbon moieties optionally comprise one or more heteroatoms, and which hydrocarbons optionally comprise substituents, and wherein any two of R1, R2, R3, R4 and R5 are optionally linked together to form a ring structure. The invention further relates to the preparation of such a compound and to the use of such a compound for preparing a pharmaceutical compound, an agrochemical compound, an intermediate for a pharmaceutical compound or an intermediate for an agrochemical compound.Type: ApplicationFiled: July 11, 2008Publication date: August 5, 2010Inventors: Gerardus Karel Maria Verzijl, Henricus Martinus Maria Gerardus Straatman, Andreas Hendrikus Maria De Vries, Lizette Schmieder, Jeroen Antonius Franciscus Boogers
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Publication number: 20100184890Abstract: The present invention relates to a group of new plasticizers for thermoplastics such as polypropylene, copolymers of polypropylene, polyethylene, polyethylene terephthalates, polystyrene and/or other polymers or mixtures of polymers containing organic and/or inorganic fillers, where the plasticizer is used for obtaining polyvinyl chloride like aspects and improved processability as well as for obtaining a better flexibility and a lower energy consumption during the processing step.Type: ApplicationFiled: January 15, 2010Publication date: July 22, 2010Inventors: Anton CONSTANTINESCU, Jose Reyes
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Publication number: 20100116749Abstract: A mixed extractant solvent that includes at least one dialkyloxycalix[4]arenebenzocrown-6 compound, 4?,4?,(5?)-di-(t-butyldicyclohexano)-18-crown-6, at least one modifier, and, optionally, a diluent. The dialkyloxycalix[4]arenebenzocrown-6 compound is 1,3-alternate-25,27-di(octyloxy)calix[4] arenebenzocrown-6, 1,3-alternate-25,27-di(decyloxy)calix[4]arene-benzocrown-6, 1,3-alternate-25,27-di(dodecyloxy)calix[4]arenebenzocrown-6, 1,3-alternate-25,27-di(2-ethylhexyl-1-oxy)calix[4]arenebenzocrown-6, 1,3-alternate-25,27-di(3,7-dimethyloctyl-1-oxy)calix[4] arenebenzocrown-6, 1,3-alternate-25,27-di(4-butyloctyl-1-oxy)calix[4]arenebenzocrown-6, or combinations thereof. The modifier is a primary alcohol. A method of separating cesium and strontium from an aqueous feed is also disclosed, as are dialkyloxycalix[4]arenebenzocrown-6 compounds and an alcohol modifier.Type: ApplicationFiled: November 10, 2008Publication date: May 13, 2010Inventors: DEAN R. PETERMAN, DAVID H. MEIKRANTZ, JACK D. LAW, CATHERINE L. RIDDLE, TERRY A. TODD, MITCHELL R. GREENHALGH, RICHARD D. TILLOTSON, RICHARD A. BARTSCH, BRUCE A. MOYER, LAETITIA H. DELMAU, PETER V. BONNESEN
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Patent number: 7625499Abstract: The present invention provides a conductive liquid-crystal material having features including that, for example, excellent conductivity is exhibited at a low threshold voltage of about 5 V even in a room temperature range, the value of resistance varies with an applied voltage, the current density rises sharply at a voltage of about 5 V, and an excellent charge mobility is exhibited, as well as a process for producing the conductive liquid-crystal material, a liquid-crystal composition which is used for the conductive liquid-crystal material, a liquid-crystal semiconductor element, and an information recording medium.Type: GrantFiled: November 30, 2005Date of Patent: December 1, 2009Assignee: Nippon Chemical Industrial Co., Ltd.Inventor: Yuichiro Haramoto
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Publication number: 20090259074Abstract: A process for the production of an alcohol compound represented by the formula (3): wherein X1, X2, X3, X4, Z, R and n are as defined below, comprising reacting a phenol represented by the formula (1): wherein X1, X2, X3 and X4 independently represent a hydrogen atom, a halogen atom or an alkyl group having 1 to 3 carbon atoms; Z represents an oxygen atom or a sulfur atom; and R represents an alkyl group, an alkenyl group, an alkynyl group, or an aralkyl group which may be substituted by a halogen atom, with a haloalcohol represented by the formula (2): wherein Y represents a chlorine atom or a bromine atom; and n represents an integer of 2 or 3, in a biphase system composed of a water-immiscible organic solvent and an aqueous alkali metal hydroxide solution in the presence of a phase-transfer catalyst.Type: ApplicationFiled: July 3, 2007Publication date: October 15, 2009Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Toru Sakamoto, Shinzo Seko