Phosphonium Derivative Patents (Class 568/9)
-
Patent number: 7829744Abstract: A primary phosphine or a secondary phosphine is reacted with an ester compound selected from the group consisting of; a phosphate triester; a phosphonate diester; a sulfate diester; and a sulfonate ester; to form a phosphonium salt of formula (VII) wherein each of RQ, RX, RY, and RZ is independently hydrocarbyl and X? is a phosphate, phosphonate, sulfate, or sulfonate. These phosphonium salts may find utility in a wide range of applications, including as surfactants, as polar solvents (ionic liquids), as antimicrobial agents, and as a component of spinning finish in polyamide fiber processing.Type: GrantFiled: March 8, 2004Date of Patent: November 9, 2010Assignee: Cytec Technology CorpInventors: Christine J. Bradaric-Baus, Yuehui Zhou
-
Publication number: 20100222580Abstract: The invention relates to a process for the preparation of onium alkylsulfates by reaction of an onium halide with a symmetrically substituted dialkyl sulfate, in which the alkyl group can have 1 to 14 C atoms, with an asymmetrically substituted dialkyl sulfate, in which one alkyl group can have 4 to 20 C atoms and the second alkyl group denotes methyl or ethyl, with an alkyl trialkylsilyl sulfate, with an alkyl acyl sulfate or with an alkyl sulfonyl sulfate, where the reaction with a dialkyl sulfate is carried out at room temperature.Type: ApplicationFiled: November 18, 2005Publication date: September 2, 2010Applicant: MERCK PATENT GMBHInventors: Nikolai Ignatyev, Urs Welz-Biermann, Andriy Kucheryna, Helge Willner
-
Publication number: 20100217037Abstract: Improved method of production of 9-(Z)-retinoic acid, in which a) a ?-formyl-crotonic acid C1-C10 alkyl or phenyl ester is reacted with an isolated 9-(Z)—C15-triarylphosphonium salt by the Wittig reaction in the presence of a base to the corresponding 9-(Z)-retinoic acid ester; which b) is then saponified with a base to the corresponding 9-(Z)-retinoic acid carboxylate and then, following protonation with an acid, the desired 9-(Z)-retinoic acid is obtained, and improved method for the enrichment and isolation of the 9-(Z)—C15-triarylphosphonium salt.Type: ApplicationFiled: September 27, 2007Publication date: August 26, 2010Inventors: Michael Stanek, Stefan Essl, Monika Knopp
-
Publication number: 20100204074Abstract: Disclosed are ionic liquids that have a low melting point. Said liquids are provided in the form of compounds that are selected among the group comprising tetraalkyl ammonium salts, benzyl trialkyl ammonium salts, tetraalkyl phosphonium salts, and benzyl trialkyl phosphonium salts, provided that at last two alkyl groups represent aliphatic radicals with chain lengths ranging from 8 to 10 C atoms, and provided that not all alkyl radicals are identical.Type: ApplicationFiled: February 23, 2007Publication date: August 12, 2010Applicant: COGNIS IP MANAGEMENT GMBHInventors: Hendrik Huesken, Paul Birnbrich, Gilbert Schenker
-
Patent number: 7754462Abstract: The invention relates to the implementation of enzyme-catalysed reactions in the presence of ionic liquids.Type: GrantFiled: May 12, 2008Date of Patent: July 13, 2010Assignee: Solvent Innovation GmbHInventors: Udo Kragl, Nicole Kaftzik, Sonja Fliege, Peter Wasserscheid
-
Patent number: 7744851Abstract: The present invention is directed to a method for preparing an anhydrous 18F-radiolabeled fluorinating agent by a nucleophilic reaction of a hydrated 18F-radiolabeled fluoride ion source with an unsaturated carrier compound; treating the 18F-radiolabeled carrier compound to produce a non-aqueous mixture of the 18F-radiolabeled carrier compound in a solvent; and reacting the 18F-radiolabeled carrier compound with a nucleophilic composition in a nucleophilic reaction to produce an anhydrous 18F-radiolabeled fluorinating agent. The present invention is also directed to an anhydrous 18F-radiolabeled fluorinating agent comprising the formula [QnM]x+(18F?)x. Additionally, the present invention is directed to an 18F-radiolabeled fluorinated radiopharmaceutical or an 18F-radiolabeled fluorinated radiotracer prepared by reacting the anhydrous 18F-radiolabeled fluorinating agent with a drug intermediate.Type: GrantFiled: July 16, 2007Date of Patent: June 29, 2010Assignee: Board Of Regents Of The University Of NebraskaInventors: Stephen Gregory DiMagno, Haoran Sun
-
Publication number: 20100160396Abstract: The present invention comprises 2-cyanobenzenesulfonic acid amides of the formula (I) and isomeric forms thereof (I-A) and (I-B) wherein R1, R2, R3, R4, R5 and A have the aforesaid meaning for the control of animal pests with the use of penetration enhancers and/or ammonium or phosphonium salts.Type: ApplicationFiled: May 21, 2008Publication date: June 24, 2010Applicant: Bayer ScropScience AGInventor: Reiner FISCHER
-
Patent number: 7723536Abstract: Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.Type: GrantFiled: February 28, 2008Date of Patent: May 25, 2010Assignee: The Trustees Of The University of PennsylvaniaInventors: Amos B. Smith, III, Thomas J. Beauchamp, Matthew J. LaMarche, Yuping Qiu, Michael D. Kaufman, Hirokazu Arimoto, David R. Jones, Kaoru Kobayashi
-
Patent number: 7709598Abstract: To obtain a polymerization initiator (acid generating agent) having excellent power for initiation of cationic polymerization without containing arsenic or antimony. Provided is a specific onium salt or transition metal complex salt of a fluorinated alkyl fluorophosphoric acid.Type: GrantFiled: May 27, 2005Date of Patent: May 4, 2010Assignee: San-Apro LimitedInventors: Hideki Kimura, Jiro Yamamoto, Shinji Yamashita, Mitsuo Kurumaya, Takaaki Sonoda
-
Patent number: 7705064Abstract: The present invention is directed to reaction products prepared from at least one Michael addition donor material including two or more active methylene hydrogens; and at least one material capable of reacting with a Michael addition donor, the material having one Michael addition acceptor and at least one functional group selected from the group consisting of hydroxy, hydroxyalkyl, vinyl ether, amino, aminoalkyl, carboxy, carboxyalkyl, cyano, and cyanoalkyl groups; or reaction products prepared from (a) at least one Michael addition donor material comprising at least one Michael Addition donor group selected from the group consisting of cyano functional groups and phosphono functional groups; and (b) at least one material capable of reacting with the at least one Michael addition donor group, the material having at least one Michael addition acceptor, wherein the above reaction products are capable of forming free radicals upon exposure to actinic radiation; as well as compositions, and processes for makingType: GrantFiled: July 23, 2007Date of Patent: April 27, 2010Assignee: Henkel CorporationInventors: Anthony F. Jacobine, John G. Woods, Joel D. Schall, Steven T. Nakos, Andrew D. Messana, David M. Glaser
-
Patent number: 7638653Abstract: Provided is a method of preparing a phosphonium compound by reacting a protic phosphonium compound represented by [(R1)—P(R2)a(R2?)b]HX and a salt compound represented by [C][Ani]. Therefore, a phosphonium compound used as a cocatalyst for the preparation of a polar cyclic olefin polymer can be produced at high yield.Type: GrantFiled: July 25, 2006Date of Patent: December 29, 2009Assignee: LG Chem, Ltd.Inventors: Sungcheol Yoon, Young Chul Won, Young Whan Park, Sung Ho Chun, Dai Seung Choi
-
Publication number: 20090312587Abstract: The present invention relates to process for the preparation of zeacarotenes and to intermediates in the process for the preparation of zeacarotenes.Type: ApplicationFiled: June 5, 2009Publication date: December 17, 2009Inventors: Andreas PUHL, Werner SIMON, Anita WEGERT
-
Publication number: 20090253907Abstract: A phosphine compound represented by general formula (1) wherein R? and R? independently are selected from alkyl, cycloalkyl and 2-furyl radicals, or R? and R? are joined together to form with the phosphorous atom a carbon-phosphorous monocycle including at least 3 carbon atoms or a carbon-phosphorous bicycle; the alkyl radicals, cycloalkyl radicals, and carbon-phosphorous monocycle being unsubstituted or substituted by at least one radical selected from the group of alkyl, cycloalkyl, aryl, alkoxy, and aryloxy radicals; Cps is a partially substituted or completely substituted cyclopentadien-1-yl group, including substitutions resulting in a fused ring system, and wherein a substitution at the 1-position of the cyclopentadien-1-yl group is mandatory when the cyclopentadien-1-yl group is not part of a fused ring system or is part of an indenyl group. These phosphines can be used as ligands in catalytic reactions.Type: ApplicationFiled: August 14, 2007Publication date: October 8, 2009Inventors: Herbert Plenio, Christoph Fleckenstein, Renat Kadyrov, Juan Almena, Axel Monsees, Thomas Riermeier
-
Patent number: 7595422Abstract: The invention relates to a novel process for conditioning isocyanates. The purpose of conditioning of isocyanates or of mixtures of isocyanates is to remove organophosphorus components in a suitable manner such that the organophosphorus compounds no longer interfere with processing of the isocyanates.Type: GrantFiled: December 20, 2007Date of Patent: September 29, 2009Assignee: Bayer MaterialScience AGInventors: Frank Richter, Andreas Hecking, Martin Brahm
-
Patent number: 7592486Abstract: Anhydrous organic fluoride salts and reagents prepared by a method comprising the nucleophilic substitution of a fluorinated aromatic or fluorinated unsaturated organic compound with a salt having the formula: [QnM]x+Ax? in an inert polar, aprotic solvent; wherein M is an atom capable of supporting a formal positive charge, the n groups Q are independently varied organic moieties, n is an integer such that the [QnM] carries at least one formal positive charge, x is an integer defining the number of formal positive charge(s), +, carried by the [QnM], A? is an anionic nucleophile capable of substituting for F in the fluorinated compound and F represents fluorine or a radioisotope thereof.Type: GrantFiled: September 15, 2005Date of Patent: September 22, 2009Assignee: Board of Regents of the University of NebraskaInventors: Stephen G. DiMagno, Haoran Sun
-
Patent number: 7560595Abstract: A non-aqueous electrolyte cell comprises a positive electrode, a negative electrode and a non-aqueous electrolyte containing a support salt. The non-aqueous electrolyte further comprises a phosphazene derivative. The phosphazene derivative having a specified structure functions as an electrode stabilizing agent or a non-combustion agent.Type: GrantFiled: June 28, 2002Date of Patent: July 14, 2009Assignee: Bridgestone CorporationInventors: Masashi Otsuki, Shigeki Endo, Takao Ogino, Yasuo Horikawa
-
Patent number: 7547807Abstract: The present invention relates to a process for preparing quaternary phosphonium salts by reacting a ternary phosphine with an optionally substituted, saturated or monounsaturated or polyunsaturated electrophile having from 3 to 25 carbon atoms in ternary solvent mixtures.Type: GrantFiled: December 14, 2004Date of Patent: June 16, 2009Assignee: BASF SEInventors: Laszlo Szarvas, Klemens Massonne, Harald Laas, Kai Michael Exner, Detlev Glas
-
Patent number: 7544807Abstract: Low melting ionic compounds of the general formula (cation) (R?SO4) in which R? is a branched or linear, saturated or unsaturated, aliphatic or alicyclic functionalized or non-functionalized hydrocarbon chain with 3-36 carbon atoms are provided. These compounds can serve as ionic liquids, e.g. as solvents or solvent additives in chemical reactions, as extraction agents or as heat carriers. The compounds comprise a cation and anionic sulfate ester.Type: GrantFiled: August 3, 2007Date of Patent: June 9, 2009Assignee: Merck Patent GmbHInventors: Peter Wasserscheid, Andreas Bösmann, Roy Van Hal
-
Patent number: 7541499Abstract: Disclosed is a process for the recovery of phosphorus and/or iodine containing catalyst components, present as an organophosphorus compound such as trihydrocarbylphosphine compounds and tetrahydrocarbylphosphonium compounds, from a solution of at least one such organophosphorus compound in an organic solvent by the steps comprising (1) converting the organophosphorus compound to an iodide complex of a organophosphonium compound which is insoluble in the organic solvent; and (2) separating the insoluble iodide complex of the organophosphonium compound from the solution. The process also results in the recovery of iodine values present in the solution.Type: GrantFiled: February 6, 2007Date of Patent: June 2, 2009Assignee: Eastman Chemical CompanyInventors: Jeffrey Scott Kanel, Stanley John Okrasinski
-
Publication number: 20090062558Abstract: The present invention relates to a new process for preparing estrogen-antagonistic 11?-fluoro-17?-alkylestra-1,3,5(10)-triene-3,17-diols of the general formula I having a 7?-(?-alkylamino-?-perfluoroalkyl)alkyl side chain and to ?-alkyl(amino)-?-perfluoro(alkyl)alkanes of the general formula II, to processes for their preparation and to the intermediates required for this purpose.Type: ApplicationFiled: August 29, 2008Publication date: March 5, 2009Inventors: Michael SANDER, Danja Grossbach, Christian Dinter, Jorma Hassfeld, David Voigtlaender
-
Patent number: 7491851Abstract: This invention provides a method for generating secondary phosphines from secondary phosphine oxides in the presence of a reducing agent, such as diisobutylaluminum hydride (DIBAL-H), triisobutyldialuminoxane, triisobutylaluminum, tetraisobutyldialuminoxane, or another reducing agent comprising: (i) an R1R2AlH moiety, wherein R1 and R2 are each an alkyl species or oxygen, and wherein at least one of R1 or R2 comprises at least 2 carbon atoms, or (ii) an R1R2R3Al moiety, wherein R1, R2, and R3 are not hydrogen, and wherein at least one of R1, R2, and R3 is an alkyl species comprising a ?-hydrogen, not including triethylaluminum. Preferred reducing agents for the present invention include: diisobutylaluminum hydride, triisobutyldialiuminoxane, triisobutylaluminum, tetraisobutyldialuminoxane, and combinations thereof.Type: GrantFiled: February 16, 2007Date of Patent: February 17, 2009Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.Inventors: Carl Alan Busacca, Jon C. Lorenz
-
Publication number: 20090036628Abstract: The present invention relates to oxonium salts having [(Ro)3O]+ cations and sulfonium salts having [(Ro)3S]+ cations, where Ro denotes straight-chain or branched alkyl groups having 1-8 C atoms or phenyl which is unsubstituted or substituted by Ro, ORo, N(Ro)2, CN or halogen, and anions selected from the group of [PFx(CyF2y+1?zHz)6?x]? anions, where 2?x?5, 1?y?8 and 0?z?2y+1, or anions selected from the group of [BFn(CN)4?n]? anions, where n=0, 1 , 2 or 3, or anions selected from the group of [(Rf1SO2)2N]? anions or anions selected from the group of [BFwRf24?w]? anions, to processes for the preparation thereof, and to the use thereof, in particular for the preparation of ionic liquids.Type: ApplicationFiled: January 5, 2007Publication date: February 5, 2009Inventors: Nikolai (Mykola) Ignatyev, German Bissky, Helge Willner
-
Patent number: 7465838Abstract: The present invention relates to a method for the preparation of C2-symmetric 1,4-diols of the formula IVA or IVB, wherein ring A, R1 and R2 have the meanings given in the specification, that makes use of the metallation of pure enantiomers of ?-(aryl or heteroaryl)-?-substituted alkanol compounds or the use of said alkanol compounds in the preparation of said mmetric 1,4-diols; novel C2-symmetric 1,4-diols in enantiomerically pure form; and methods of use or their use in the synthesis of chiral ligands which find use to produce catalysts for a variety of asymmetric transformations such as hydrogenations.Type: GrantFiled: September 23, 2003Date of Patent: December 16, 2008Assignee: Ciba Specialty Chemical Corp.Inventor: Ulrich Berens
-
Publication number: 20080287686Abstract: An 'onium salt, e.g. a quaternary ammonium salt, of an anionic dye maybe prepared by mixing an aqueous solution of a salt of the dye with a solution of a water-insoluble 'onium salt in an organic solvent, and separating a solution of the 'onium salt of the anionic dye in the organic solvent from the residual aqueous solution.Type: ApplicationFiled: December 18, 2006Publication date: November 20, 2008Applicant: Sun Chemical CorpInventor: Robert Lines
-
Publication number: 20080255391Abstract: A process for the stereoselective preparation of a P-chiral four-co-ordinated phosphorus compound, the process comprising reacting a first reactant selected from the group consisting of a chiral alcohol, chiral amine or chiral thiol, with a second reactant comprising a P-chiral three-co-ordinated phosphorus compound, in the presence of an electrophile.Type: ApplicationFiled: June 1, 2005Publication date: October 16, 2008Applicant: University College Dublin National University of IrelandInventors: Declan Gilheany, Shane B. Robinson, Enda Bergin, Denise M. Walsh, Audrius Rimkus, Eoin F. Clarke, Brian G. Kelly, Eoghan M. McGarrigle, Colm P. O'Mahony, Cormac T. O'Connor
-
Publication number: 20080194831Abstract: The present invention relates to ionic liquids of low viscosity and high electrochemical stability, in particular for use in the area of electrochemistry and as solvents for carrying out chemical reactions.Type: ApplicationFiled: May 12, 2006Publication date: August 14, 2008Inventors: Nikolai (Mykola) Ignatyev, Urs Welz-Biermann, Michael Heckmeier, German Bissky, Helge Willner
-
Publication number: 20080166243Abstract: The invention relates to a liquid for compressing a gaseous medium which transfers the force required for compression directly to the gas. The liquid has a vapour pressure of less than 10?3 mbar.Type: ApplicationFiled: May 3, 2006Publication date: July 10, 2008Inventors: Michael Kotschan, Roland Kalb
-
Patent number: 7393980Abstract: The invention relates to a novel method for producing nucleophilic substitutions, particularly of type SNAr and SN2. More specifically, the invention relates to the use as a fluorinating reaction medium of ionic liquid or fused salt comprising at least four carbon atoms. The invention can be used for the synthesis of fluoride derivatives.Type: GrantFiled: May 16, 2002Date of Patent: July 1, 2008Assignee: Rhodia ChimieInventors: Maxime Garayt, Virginie Le Boulaire, Danielle Gree, René Gree, Vincent Schanen, Jean-Francis Spindler
-
Publication number: 20080149888Abstract: A storage medium and a method for storing hydrogen is disclosed. The storage medium has at least one ionic compound capable of hydrogenation or consists at least partially of at least one ionic compound capable of hydrogenation. The ionic compounds are present in liquid and/or solid form.Type: ApplicationFiled: September 20, 2005Publication date: June 26, 2008Inventors: Robert Adler, Roland Kalb, Wolfgang Wesner
-
Patent number: 7378194Abstract: The invention concerns novel ionic compounds with low melting point whereof the onium type cation having at least a heteroatom such as N, O, S or P bearing the positive charge and whereof the anion includes, wholly or partially, at least an ion imidide such as (FX1O)N?(OX2F) wherein X1 and X2 are identical or different and comprise SO or PF, and their use as solvent in electrochemical devices. Said composition comprises a salt wherein the anionic charge is delocalised, and can be used, inter alia, as electrolyte.Type: GrantFiled: October 1, 2004Date of Patent: May 27, 2008Assignees: ACEP, Inc., Centre de la Recherche Scientifique, Universite de MontrealInventors: Christophe Michot, Michel Armand, Michel Gauthier, Nathalie Ravet
-
Patent number: 7368585Abstract: Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.Type: GrantFiled: July 13, 2006Date of Patent: May 6, 2008Assignee: The Trustees Of The University Of PennsylvaniaInventors: Amos B. Smith, III, Thomas J. Beauchamp, Matthew J. LaMarche
-
Patent number: 7348458Abstract: A tetraalkylphosphonium salt having at least one branched alkyl chain containing 9 to 100 carbon atoms in total, an organically modified layered silicate containing the tetraalkylphosphonium salt having at least one branched alkyl chain containing 9 to 100 carbon atoms in total between layers of a layered silicate and a composition comprising the organically modified layered silicate and an organic solvent or a thermoplastic resin. There are provided a tetraalkylphosphonium salt for a layered silicate having thermal stability and dispersibility superior to those of conventional organophilized layered silicates, an organically modified layered silicate containing the tetraalkylphosphonium salt and a composition thereof.Type: GrantFiled: March 24, 2004Date of Patent: March 25, 2008Assignee: FUJIFILM CorporationInventors: Taisei Nishimi, Koki Nakamura
-
Publication number: 20080032949Abstract: A phosphonium compound embedded in a matrix substrate wherein the phosphonium compound is selected from a group consisting of tris (hydroxyorgano) phosphine (THP), a THP+ salt (tetrakis (hydroxyorgano) phosphonium salt) or a condensate of THP and a nitrogen containing compound. The compound may be used to reduce the numbers of micro organisms in industrial systems and may also be used to reduce iron carbonate or iron, lead and zinc scale deposits.Type: ApplicationFiled: February 21, 2005Publication date: February 7, 2008Inventors: Christopher Jones, Raul Diaz
-
Publication number: 20080033176Abstract: A method for preparing a prostaglandin derivative represented by the following general formula (I): (wherein Ph represents phenyl group, R1 represents a C1-7 alkyl group, a C1-7 alkenyl group, phenyl group, or benzyl group), which comprises the successive steps (1) to (8) described in the specification, or any one step or two or more successive steps selected from the group consisting of the steps (1) to (8). A method for efficiently, inexpensively and safely preparing prostaglandin derivatives, of which typical example is latanoprost, is provided.Type: ApplicationFiled: March 20, 2007Publication date: February 7, 2008Applicant: DAIICHI FINE CHEMICAL CO., LTD.Inventors: Noriaki MURATA, Atsunori ARAMATA
-
Patent number: 7297289Abstract: Electrical storage devices having excellent low-temperature properties can be obtained by using a quaternary salt (or ionic liquid) of general formula (1) below as an electrolyte salt for electrical storage devices or a liquid electrolyte for electrical storage devices. In formula (1), R1 to R4 are each independently an alkyl group of 1 to 5 carbons or an alkoxyalkyl group of the formula R?—O—(CH2)n—, with the proviso that at least one group from among R1 to R4 is the above alkoxyalkyl group. X is a nitrogen or phosphorus atom, and Y is a monovalent anion.Type: GrantFiled: March 25, 2002Date of Patent: November 20, 2007Assignee: Nisshinbo Industries, Inc.Inventors: Takaya Sato, Gen Masuda, Ryutaro Nozu, Tatsuya Maruo
-
Patent number: 7288679Abstract: A device comprises at least one organophosphonium transition metal dye or is provided with a filter, comprising at least one organophosphonium transition metal dye, wherein, in a particular embodiment said device is selected from the group consisting of a scanner, a digitizer, a display and a photographic device.Type: GrantFiled: August 6, 2004Date of Patent: October 30, 2007Assignee: AGFA-GevaertInventors: Luc Vanmaele, Paul Leblans, Luc Struye
-
Publication number: 20070191606Abstract: The present invention provides novel 2,2-bis(4-hydroxyphenyl)-alkyl onium salts as illustrated by 2,2-bis(4-hydroxyphenyl)-tridecyl(1,2-dimethylimidazolium)bromide and a process for preparation thereof by hydroxyalkylating acetoacetate to the corresponding hyroxyalkylacetoacetate, dealkoxycarbonylating the hydroxyalkyl acetoacetate to ?-hydroxyalkan-2-one and contacting the ?-hydroxyalkan-2-one with phenol in the presence of an acidic catalyst to give 2,2-bis(4-hydroxyphenyl)alkanol, brominating the 2,2-bis(4-hydroxyphenyl)alkanol to 2,2-bis(4-hydroxyphenyl)alkyl bromide, quaternizing 1,2-dimethylimidazole with the 2,2-bis(4-hydroxyphenyl)alkyl bromide to 2,2-bis(4-hydroxyphenyl)alkyl(1,2-dimethylimidazolium)bromide. The products can be used as reactive modifiers for layered phyllosilicates that can be used in the preparation of polymer-nanocomposites, wherein the said polymers are prepared from 2,2-bis(4-hydroxyphenyl)propane as one of the reacting monomers.Type: ApplicationFiled: October 13, 2006Publication date: August 16, 2007Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Shroff Rama Mallikarjuna, Swaminathan Sivaram
-
Patent number: 7250535Abstract: A production process by which tertiary phosphine with an attached sterically bulky hydrocarbon group is produced in a high yield and with high purity on an industrial scale through simple and safe operations by allowing a dialkylphosphinous halide to react with a Grignard reagent in the presence of a copper compound in an amount corresponding to 0.1 to 5% by mol based on the dialkylphosphinous halide to produce tertiary phosphine represented by the following formula (3): wherein R1 and R2 are each a tertiary hydrocarbon group of 4 to 13 carbon atoms, and R3 is an alkyl group, an alkenyl group, an aryl group or the like.Type: GrantFiled: February 3, 2003Date of Patent: July 31, 2007Assignee: Hokko Chemical Industry Co., Ltd.Inventors: Shinya Maehara, Hideyuki Iwazaki
-
Patent number: 7230136Abstract: The invention relates to a process for synthesizing tertiary phosphines by reacting halophosphines with organomagnesium compounds in the presence of copper compounds and optionally of salts.Type: GrantFiled: April 17, 2003Date of Patent: June 12, 2007Assignee: LANXESS Deutschland GmbHInventors: Florian Rampf, Hans-Christian Militzer
-
Patent number: 7230137Abstract: The invention relates to a process for the preparation of cycloorganylphosphanes of formula 1 (R1P)n by reaction of dihalo(organyl)phosphanes of formula R1PHal2 with: a) activated zinc in an organic solvent, or with: b) an alkali metal or alkaline earth metal in a non-polar organic solvent in the presence of an activator, wherein R1 is C1–C12alkyl; C3–C12 cycloalkyl, aryl or heteroaryl, Hal is F, Cl, Br or I, and n is a number from 3 to 20. The invention relates also to novel di(alkali metal/alkaline earth metal) oligophosphanediides and to the use thereof in the preparation of organophosphorus compounds.Type: GrantFiled: November 24, 2003Date of Patent: June 12, 2007Assignee: Ciba Specialty Chemicals Corp.Inventors: Hansjörg Grützmacher, Jens Geier, Hartmut Schönberg, Markus Scherer, Daniel Stein, Souâd Boulmaâz
-
Patent number: 7223879Abstract: One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.Type: GrantFiled: December 9, 2003Date of Patent: May 29, 2007Assignee: Massachusetts Institute of TechnologyInventors: Stephen L. Buchwald, Xiaohua Huang, Danilo Zim
-
Patent number: 7208605Abstract: One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze a Bronsted-acid-catalyzed chemical reaction. A third aspect of the present invention relates to ionic liquids comprising a pendant nucleophilic group, e.g., an amine. Still another aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to catalyze a nucleophile-assisted chemical reaction. A fifth aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to remove a gaseous impurity, e.g., carbon dioxide, from a gas, e.g., sour natural gas.Type: GrantFiled: April 4, 2003Date of Patent: April 24, 2007Assignee: University of South AlabamaInventor: James Hillard Davis, Jr.
-
Patent number: 7196227Abstract: Disclosed is a process for the recovery of phosphorus and/or iodine containing catalyst components, present as an organophosphorus compound such as trihydrocarbylphosphine compounds and tetrahydrocarbylphosphonium compounds, from a solution of at least one such organophosphorus compound in an organic solvent by the steps comprising (1) converting the organophosphorus compound to an iodide complex of a organophosphonium compound which is insoluble in the organic solvent; and (2) separating the insoluble iodide complex of the organophosphonium compound from the solution. The process also results in the recovery of iodine values present in the solution.Type: GrantFiled: December 18, 2003Date of Patent: March 27, 2007Assignee: Eastman Chemical CompanyInventors: Jeffrey Scott Kanel, Stanley John Okrasinski
-
Patent number: 7179928Abstract: The methods of preparing quinols and quinones typified by mitoquinol and mitoquinone where a compound typified by idebenone is reacted with Ph3PHX and Ph3P, where X is a halogen atom.Type: GrantFiled: August 12, 2002Date of Patent: February 20, 2007Assignee: Antipodean Pharmaceuticals, Inc.Inventors: Robin Andrew James Smith, Michael Patrick Murphy
-
Patent number: 7148176Abstract: The present invention is directed to phosphine ligands and the use of such ligands in catalytic complexes with transition metals. The catalysts may be used in a variety of reactions and are especially useful for refining halogenoaromatics.Type: GrantFiled: July 27, 2001Date of Patent: December 12, 2006Assignee: Degussa AGInventors: Matthias Beller, Wilhelm Hubert Ehrentraut, legal representative, Theresia Elisabeth Ehrentraut, legal representative, Christa Fuhrmann, Alexander Zapf, Andreas Ehrentraut, deceased
-
Patent number: 7105714Abstract: The present invention provides a method of preparing a phosphonium salt of the formula [R1R2R3P—CR4R5R6]X, comprising ball-milling a phosphine of the formula R1R2R3P with a compound of the formula XCR4R5R6; a method of preparing a phosphorus ylide of the formula R1R2R3P?CR4R5, comprising ball-milling a phosphonium salt of the formula [R1R2R3P—HCR4R5]X in the presence of a base; and a method of preparing an olefin of the formula R4R5C?CR7H or R4R5C?CR7R8, comprising ball-milling a phosphorus ylide of the formula R1R2R3P?CR4R5 with a compound of the formula R7C(O)H or R7C(O)R8. The inventive method produces phosphonium salts and phosphorus ylides by mechanical processing solid reagents under solvent-free conditions.Type: GrantFiled: December 22, 2003Date of Patent: September 12, 2006Assignee: Iowa State University Research Foundation, Inc.Inventors: Vitalij K Pecharsky, Viktor P Balema, Jerzy W Wiench, Marek Pruski
-
Patent number: 6946578Abstract: An improved phenoxyphosphazene compound is produced by treating a phenoxyphosphazene compound with (a) at least one adsorbent selected from activated carbon, silica gel, activated alumina, activated clay, synthetic zeolite and macromolecular adsorbents, (b) at least one reagent selected from metal hydrides, hydrazine, hypochlorites, thiosulfates, dialkyl sulfuric acids, ortho esters, diazoalkanes, lactones, alkanesultones, epoxy compounds and hydrogen peroxide, or (c) both the adsorbent and reagent, thereby reducing the acid value of said phosphazene compound to lower than 0.025 mgKOH/g.Type: GrantFiled: December 23, 2003Date of Patent: September 20, 2005Assignee: Otsuka Chemical Co., Ltd.Inventors: Shinji Nakano, Yuji Tada, Tadao Yabuhara, Takashi Kameshima, Yoichi Nishioka, Hiroyuki Takase
-
Patent number: 6919291Abstract: Zwitterionic compositions of matter comprising cations [Ct]+ and anions connected together with substantially rigid fluorinated linking groups are described. These zwitterionic compositions serve as cocatalysts. They activate olefin polymerization catalysts, and can dissolve in aliphatic solvents. Synthesis and polymerization are illustrated.Type: GrantFiled: October 31, 2001Date of Patent: July 19, 2005Assignee: ExxonMobil Chemical Patents Inc.Inventor: George Rodriguez
-
Electrochemically stable onium salts and electrolytes containing such for electrochemical capacitors
Publication number: 20040222401Abstract: Based on the discovery that the melting point and solubility of onium salts are affected by the asymmetry of the substitution on cation, and that the branched substituents effectively shield onium cations from electrochemical reduction, new onium salts are synthesized and high performance electrolytes based on these salts for electrochemical capacitor are provided. The composition of the new electrolyte comprises an onium salt or mixture of such onium salts dissolved in aprotic, non-aqueous solvents or mixture of such solvents. The electrolyte is able to perform at high rate of charge/discharge, at low ambient temperatures, and within wide operating voltage, due to the high solubility, low melting temperature, and the improved reduction stability of the new onium cations, respectively.Type: ApplicationFiled: May 28, 2004Publication date: November 11, 2004Inventors: Kang Xu, Shengping Ding, T. Richard Jow -
Publication number: 20040171833Abstract: One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.Type: ApplicationFiled: December 9, 2003Publication date: September 2, 2004Inventors: Stephen L. Buchwald, Xiaohua Huang, Danilo Zim