Abstract: A system and method for altering a selective area of tissue in a patient uses an MRI system including a coil array having a plurality of separate coil elements. Each coil element is coupled to a respective one of the RF transmitters. The method includes identifying a target tissue area in a patient and selecting a pulse sequence configured to produce a prescribed RF field at target tissue area to heat the target tissue area. An agent is administered to the patient that is configured to enhance a medical procedure and the pulse sequence is applied to the patient using the coil elements to heat the target tissue area sufficiently to assist the agent with enhancing the medical procedure. The method further includes performing a medical imaging process to at least monitor heating of the target tissue area.

Abstract: Disclosed is a dynamic and static magnetic pulse physical therapeutic apparatus which can provide an energy superposition field of dynamic magnetic pulses including mechanical vibration, a pulse magnetic field, a permanent magnetic field, thermal radiation and far infrared radiation and an energy superposition field of static magnetic pulses including a pulse magnetic field, a permanent magnetic field, thermal radiation and far infrared radiation, individually or at the same time. It includes a shell, a far infrared radiation fin with a heating device, a plurality of annular permanent magnets and a control circuit; a dynamic magnetic pulse assembly or a static magnetic pulse assembly is provided at the center of the annular permanent magnet.

Abstract: A novel cutter instrument uses radiofrequency (RF) electrosurgery and RF energy to achieve the desired cutting action with minimum of mechanical force, thereby reducing the risk of tissue damage due to excessive mechanical cutting action. Preferably, a cutter head of the instrument comprises an outer tube of electrically-insulating material with an aperture into which is telescoped an inner electrically-conductive tube. When the working or leading end of the latter is reciprocated across the aperture in the outer tube while RF electrosurgical currents are applied to the inner tube, the cutting action of tissue entering the aperture takes place primarily via the RF electrosurgical currents.

Abstract: The present invention relates to a device for simultaneously treating a tumor or cancerous growth with both hyperthermia and X-ray radiation using brachytherapy. The device includes a needle-like introducer serving as a microwave antenna. Microwaves are emitted from the introducer to increase the temperature of cancerous body tissue. The introducer is an inner conductor of a coaxial cable. The introducer contains a hollow core which houses an X-ray emitter. The X-ray emitter is connected to a high voltage miniature cable which extends from the X-ray emitter to a high voltage power source. The X-ray emitter emits ionizing radiation to irradiate cancerous tissue. A cooling system is included to control the temperature of the introducer. Temperature sensors placed around the periphery of the tumor monitor the temperature of the treated tissue.

Abstract: The present invention provides a method/system for remote and local controlled delivery of pharmaceutical compounds or biomolecule collection using electromagnetic energy. Controlled electromagnetic energy driven systems are integrated into patches and other delivery devices. Also provided is a drug delivery or biomolecule collection patch electronically monitored by global positioning system.

Abstract: The present technique is associated with geographically locating a medical resource. The technique allows a client to interact with a remote medical resource locator system via a network interface, and to enter and transmit client data to the medical resource locator system for a location analysis. Accordingly, the client receives a resource location report based on a desired geographic region for the medical resource.

Abstract: A method for site specific treatment of diseased tissue in a patient, comprising the steps of: (i) selecting at least a magnetic material which has a magnetic heating efficiency of at least about 4.5.times.10.sup.-8 J.m./A.g, when magnetic field conditions are equal to or less than about 7.5.times.10.sup.7 A/s; (ii) delivering the magnetic material to diseased tissue in a patient; and (iii) exposing the magnetic material in the patient to a linear alternating magnetic field with a frequency of greater than about 10 kHz and a field strength such that the product of field strength, frequency and the radius of the exposed region is less than about 7.5.times.10.sup.7 A/s to generate hysteresis heat in the diseased tissue.

Abstract: The present invention provides an improved method for treatment of diseased tissue, which comprises the steps of:(i) selecting at least a magnetic material which has a magnetic heating efficiency of at least about 4.5.times.10.sup.-8 J.m./A.g, when rotational magnetic field conditions are equal to or less than about 5.times.10.sup.8 A/m.s;(ii) delivering the magnetic material to a patient's diseased tissue; and(iii) exposing the magnetic material to a rotational magnetic field with a frequency of greater than about 10 kHz and a field strength selected such that the product of field strength, frequency and the radius of the exposed region is less than about 7.5.times.10.sup.7 A/s to generate hysteresis heat in the diseased tissue.

Abstract: A method of selectively heating targeted cells within a specimen while avoiding heating of non-targeted cells is provided. The method comprises the steps of:(a) determining at least one combination of magnetic field strength and radio wave frequency (strength-frequency combination) at which only the targeted cells will resonate when the magnetic field and the electromagnetic radiation are applied to the specimen orthogonal to one another; and(b) applying a magnetic field and a radio frequency wave to the targeted cells, the strength of the magnetic field and the frequency of the radio wave corresponding to the strength-frequency combination to the targeted cells, in order to cause nuclear magnetic resonance in the targeted cells, thereby increasing the temperature of only the targeted cells.

Abstract: An improved electrode apparatus for use with an endoscopic surgical instrument provides an adjustable volume of tissue ablation and may be used with an RF energy source in either monopolar or bipolar output mode. The electrode apparatus may be used in any endoscopic surgical application, and provides a new method for any endoscopic treatment involving soft tissue ablation, including hysteroscopic and laparoscopic treatment of uterine fibroids/myomas.

Abstract: A non-ionizing radiation emitting apparatus and method of use for preferentially inducing cellular necrosis in abnormal cells has a non-ionizing radiation generator with opposing plates or poles. A time focused electromagnetic field with sufficient energy to cause either electroporation or electromagnetic enzyme interference of the abnormal cells is included and functions by rotating the generated radiation about a central axis thereby focusing the radiation at a desired location containing at least a portion of the abnormal cells.

Abstract: Disclosed is a process of thermal treatment in a tissue comprising embedding an implant element in an organism and externally applying a high frequency magnetic field characterized in that the implant element comprises a magnetic exothermic member partially or completely covered with a non-magnetic insulating film.According to the present invention, the temperature range required in the process of medical treatment in tissue (42.degree. C. to 43.degree. C.) can be more effectively maintained compared with a conventional magnetic exothermic member. Because of the complete coverage with an insulating film, a magnetic exothermic member having a higher Curie temperature than that of the conventional magnetic exothermic member can also be employed. The magnetic exothermic member can provide an isotropic exothermic characteristic when the powders are molded and the components of the magnetic exothermic member never dissolve in a living body.

Abstract: A method of treatment of a tumor comprising the steps of catheterization of the arterial vessel that feeds the tumor, and transcatheter administration of a suspension of magnetically hard ferromagnetic material in an oil solution of an oil-soluble antitumor substance with simultaneous application of local magnetic field onto the area of the tumor. After 1-3 days the tumor is subjected to ultrahigh radio frequency electromagnetic field or ultrasonic waves to produce heating of the tumor tissue to the temperature of 43.0.degree.-43.5.degree. C. for a period of 5-45 minutes.

Abstract: A hyperthermia device includes a pair of magnetic poles for applying an alternating magnetic field in a body to be heated, these two magnetic poles being laterally arranged on the surface of the body and having time varying polarities opposite to each other, and allowing a line of magnetic force including a component perpendicular to the surface of the body in the vicinity of these magnetic poles.

Abstract: In a CT image of a living body, contours of internal organs thereof are discriminated. Parameters are beforehand stored in a memory for a plurality of internal organs of the living body. Applicators are attached onto the living body and then a high frequency power is applied to electrodes disposed therein so as to heat an internal portion of the body. Based on an intensity of an electric field generated in the body due to the applied power and the parameters stored in the memory, a temperature distribution on the CT image is estimated. To retain an estimated temperature of an objective tumor at a predetermined target temperature, the high frequency power and the cooling water in the applicators are controlled. In the estimation of the temperature distribution, the parameters of the living body are repeatedly corrected to minimize a discrepancy between a temperature measured at a preset position and an estimated temperature associated therewith.

Abstract: The invention contemplates controlled ablation of the cornea, using ultraviolet laser radiation, wherein irradiated flux density and exposure time are so controlled as to achieve desired depth of the ablation. Sculpturing action results from precharacterized distribution of flux density across the cross-section of laser-beam projection, in the context of beam size, at cornea incidence, to match the area to be ablated, and the duration of exposure determines the extent of curvature change. Illustrative techniques and situations are disclosed, for myopia correction, for hyperopia correction, and for astigmatism correction.

Abstract: A method is provided wherein a suspension containing ferromagnetic particles is introduced into a body, and the particles are caused to move towards a tumor and are retained there by a magnetic field. The area of the tumor is exposed to an electromagnetic field to carry out hyperpyrexia of the tumor to a temperature sufficient to kill cancer cells. The contents of the tumor are removed. The condition of a patient's body is monitored during the treatment by determining activity of neutrophils and macrophages. An apparatus is also provided for carrying out the method and comprises an electromagnetic radiation source with emitters, temperature pickups, and a temperature setter connected to inputs of a comparator, a temperature control unit for controlling hyperpyrexia temperature connected to an output of the comparator and forming a signal fed to a control input of the source of radiation.

Abstract: Gas, gaseous precursors and prefluorocarbons are presented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.

Abstract: Apparatus for treating neoplasms in humans and animals comprising a hollow toroidal applicator which resonates at a specific radiofrequency, and which possess electrically conductive walls on which radial radiofrequency currents flow and generate a high density of uninterrupted magnetic flux within the hollow body. A rotatable antenna connected to a source of radiofrequency power is mounted inside the applicator body to couple with the electromagnetic field of the applicator. The body part to be treated is interposed through side apertures or through the space created by removing a segment of the toroid which can have orifices of predetermined cross sectional areas across which a tubular zone of high magnetic flux travels through the interposed tumor and normal tissue to induce more heat in the interposed tumor tissue than in the interposed normal tissue.

Abstract: A diathermy unit has a power oscillator with a resonant circuit arranged to be coupled to the load represented by the tissue to be treated. The resonant circuit includes a capacitor for connection in series with the load such that the resonant frequency varies with the load resistance. The resulting self-tuning of the oscillator allows improved matching of the oscillator to the load with consequent improved efficiency, a feature especially useful for a battery-powered unit. Regulation of the output power of the unit makes use of a feedback loop including an analogue multiplier for receiving signals representative of the power of the output stage, the resulting product signal being used to control pulse width modulation of the oscillator.

Abstract: A heating apparatus suitable for use in medical heat treatment of an affected portion of a human body employs a cavity resonator supplied with high-frequency energy from a high-frequency power supply unit. The cavity resonator comprises a cavity formed of a conductive material and at least one inner protrusion in said cavity generating a standing wave electric field for heating a body or body part introduced into the cavity. The inner protrusion may be a separate conductor or may be formed by deforming a portion of the conductor forming the cavity. A highly concentrated standing wave electric field and a surrounding electromagnetic field are produced in the cavity resonator when it is energized from the high-frequency power supply unit. The concentrated standing wave electric field intensively heats a desired local portion of the body and deep parts of the body may be heated satisfactorily.

Abstract: A treatment of infectious diseases and enhancement of genetic engineering processes is described comprising the use of external electromagnetic energy to alter electric and magnetic dipoles intracellularly.The process comprises introducing minute particles into the interior of cells in a host organism. These particles are capable of affecting the intracellular conductivity, dielectric properties, dipole content and membrane characteristics of the cell and nucleus. The particles are introduced intravenously, intra-arterially, and/or intra-lymphatically and the organism is then exposed to an alternating electromagnetic field to introduce energy into the cells.

Abstract: A method is provided wherein a suspension containing ferromagnetic particles is introduced into a body, and the particles are caused to move towards a tumor and are retained there by a magnetic field. The area of the tumor is exposed to an electromagnetic field to carry out hyperpyrexia of the tumor to a temperature sufficient to kill cancer cells. The contents of the tumor are removed. The condition of a patient's body is monitored during the treatment by determining activity of neutrophils and macrophages. An apparatus is also provided for carrying out the method and comprises an electromagnetic radiation source with emitters, temperature pickups, and a temperature setter connected to inputs of a comparator, a temperature control unit for controlling hyperpyrexia temperature connected to an output of the comparator and forming a signal fed to a control input of the source of radiation.

Abstract: The liposome compositions entrapping a drug are prepared by constituting the liposomal membrane with saturated phospholipids and anionic surfactants of high Krafft point at concentrations above their critical micelle concentrations. Thus obtained compositions circulate stably in blood for a long time after intravenous administration.

Abstract: A process for following the exact distribution of particles in living neurological or neuromuscular tissue and cells. The process includes introducing particles into the tissue and cells, and thereafter measuring the alteration in dielectric properties, conductivity and frequency dependent dispersion curves of the tissue and cells.

Abstract: A method of creating connections between blood vessels and other biological structures by the application of electromagnetic energy capable of the generation of heat and biophysical alterations in intracellular particles and particles within the edges of the biological structure as well as within the edges of the biological structure itself. The process allows for the creation of connection between biological structures without damaging the biological structures themselves.The process comprises introducing minute particles into the edges of the biological structures to be connected. These particles are either intracellular and/or extracellular and can be introduced at the time of connection and/or prior to connection. These particles are suspended in an appropriate solution and are of a size generally having a diameter of approximately 1 micron or less and are of a material with properties such as ferromagnetic, paramagnetic or diamagnetic so as to be inductively heated when subjected to the radiation.