Abstract: Disclosed is a transcranial magnetic stimulation (TMS) stimulation navigation method comprising the steps of: acquiring a stimulation target point in the brain of a subject to which an electrical stimulus is to be applied; acquiring data on the spatial distribution of a magnetic vector potential of a coil for a TMS procedure; acquiring, from the spatial distribution, at least one parameter for acquiring an optimal stimulation condition for the stimulation target point; and by using the acquired parameter, calculating a position and direction of the coil satisfying the optimal stimulation condition for the stimulation target point.

Abstract: Various embodiments of the present disclosure are directed towards a therapeutic furniture apparatus. The therapeutic furniture apparatus includes a non-magnetic base. The non-magnetic base has a vertical portion that extends vertically from the base, and a horizontal portion that extends from the vertical portion at a first location over the non-magnetic base. A non-magnetic ring attachment structure is coupled to the horizontal portion of the non-magnetic support structure at a second location disposed directly over the non-magnetic base. The non-magnetic ring attachment structure extends from the horizontal portion toward the non-magnetic base. A plurality of non-magnetic ring structures are coupled to the non-magnetic ring attachment structure and disposed between the horizontal portion of the non-magnetic support structure and the non-magnetic base. A plurality of permanent magnets are disposed at regular intervals on each of the plurality of non-magnetic ring structures.

Abstract: The present specification discloses a pulsed electromagnetic field system having planar microcoil arrays integrated into clothing. Each of the planar microcoil arrays has two or more planar microcoils positioned on a flexible substrate. The planar microcoil arrays are connected to a controller configured to generate an electrical current and transmit that electrical current, in accordance with a particular stimulation protocol, to each of the planar microcoil arrays.

Abstract: A portable apparatus for generating an induced low-frequency sinusoidal electric current in an area of the human body includes four angular magnet sectors inscribed within the same circle, centered on the same axis of rotation, and spaced angularly apart from one another. The polarity of two adjacent angular magnet sectors is opposed, and a motor for rotating at a predetermined speed the angular magnet sectors is about the axis of rotation to generate an induced sinusoidal current at a predefined frequency. Each angular magnet sector includes the same geometrical shape with an internal angular opening of 90°, an external angular opening between 20° and 50°, and two lateral edges defining a radius extending over a distance, which is between one-third and two-thirds of a distance separating the axis of rotation from the free end of the magnet sectors.

Abstract: Leadless, implantable microstimulators for treating chronic inflammation. These devices can include a static magnetic field detector (e.g., non-Hall effect sensors/detectors, including those based on a Wiegand effect or generating pulses at a predetermined frequency range and using a detection circuit to determine the decay rate of the pulses), to trigger an emergency shut off of the micro stimulator. Also described are methods and apparatuses for regulating the temperature of an implant based applied power from a charger (e.g., voltage across the charger when unloaded and when loaded by the implant) to yield a power control loop correlated with the power drawn by the implant to determine temperature of the implant. A negotiation protocol can exchange data between the charger and the implant (e.g., type of charger, type of implant, nature of the coupling between the two, etc.) to set target power control loop parameters to estimate and regulate implant temperature.

Abstract: A cancer treatment apparatus including a magnetic field generator that generates a magnetic field of 100 kHz to 300 kHz to be applied to affected tissues.

Abstract: A method for treating a subject by applying one or more pulsed electromagnetic field (PEMF) signals, the method including: providing an array of a plurality of loop antennas coupled to a corresponding one or more generator circuits in an enclosure configured to house at least the array of plural loop antennas, the enclosure including a treatment surface configured to be placed proximate the subject; activating one or more of the generator circuits to generate one or more preliminary treatment signals to corresponding one or more of the loop antennas; detecting a presence of the subject; and upon a condition of detecting the subject being proximate the treatment surface, activating the one or more of the generator circuits to generate another one or more treatment signals associated with the subject to the corresponding one or more loop antennas.

Abstract: All fluids, when placed within a Kukharev region at a moment of gravitational resonance, form vibrations of different frequencies within themselves. If, at the same moments of gravitational resonance, forced oscillations of the same frequency are provided as a treatment on a living organism, a double resonance is formed within the fluid, and a sharp increase in the amplitude of oscillations within the fluid formed as a result of the double resonance in turn causes the destruction of the fluid. The method is determined utilizing Kukharev region data on the particular fluid desired to be destroyed or otherwise removed from the living organism. By further fine-tuning the forced oscillation (i.e., the directed radiation), the natural oscillations of the base fluid can be further adjusted to modify the fluid's properties.

Abstract: Disclosed are apparatuses and methods for reducing or limiting blood loss and reducing bleed time in a subject by combined vagus and trigeminal stimulation. The apparatuses and methods may activate (e.g., electrically) one or more branches of the trigeminal nerve and may concurrently (at overlapping or near-overlapping time) independently activate the vagus nerve. This activation may be invasive or non-invasive.

Abstract: The invention relates to a device for generating a very-low-frequency pulsed magnetic field carried by a very-low-frequency alternating magnetic field and intended to be applied to a region of the human body, the device is provided with a plurality of pairs of angular magnet sectors of opposite polarity, the pairs of angular magnet sectors being centered on one same axis of rotation, angularly spaced apart from one another, and set in rotation at a predetermined speed about the axis of rotation so as to generate an alternating magnetic field at a predefined frequency, and at least one conductive wire coil centered on the axis of rotation of the angular magnet sectors and supplied with a pulsed electric current so as to generate a pulsed magnetic field superimposed over the alternating magnetic field generated by the setting in rotation of the angular magnet sectors.

Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, where brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.

Abstract: The method for magnetic resonance imaging described in the present disclosure may include generating an inversion recovery image by scanning an object using an inversion recovery sequence. The method may also include generating a real part image corresponding to the inversion recovery image by processing the inversion recovery image. The method may also include obtaining a signal line of a reference image without inversion recovery, the reference image corresponding to the real part image. The method may also include determining a phase-corrected signal line of the reference image by performing a phase correction on the signal line of the reference image. The method may also include determining a polarity of the real part image based on the phase-corrected signal line of the reference image.

Abstract: The disclosure describes a method and system that allows a user to configure electrical stimulation therapy by defining a three-dimensional (3D) stimulation field. After a stimulation lead is implanted in a patient, a clinician manipulates the 3D stimulation field in a 3D environment to encompass desired anatomical regions of the patient. In this manner, the clinician determines which anatomical regions to stimulate, and the system generates the necessary stimulation parameters. In some cases, a lead icon representing the implanted lead is displayed to show the clinician where the lead is relative to the 3D anatomical regions of the patient.

Abstract: The field of the disclosure relates generally to cancer cell destruction and, more specifically, to cancer cell destruction by photo-magnetic irradiation mediated multimodal therapy using smart nanostructures.

Abstract: In general, techniques, methods, systems, and devices for delivering high frequency neurostimulation to control one or more pelvic disorders are described. In one example, a method includes identifying, by a medical device configured to be at least partially implanted in a patient, an indication to inhibit bladder activity. The medical device generates, in response to identifying the indication, electrical stimulation therapy comprising first electrical stimulation pulses comprising a first frequency greater than or equal to about 500 Hertz and less than or equal to about 5,000 Hertz. Further, the medical device delivers the electrical stimulation therapy to a target nerve selected from a group consisting of: a sacral nerve, a pelvic nerve, a tibial nerve, and a pudendal nerve of the patient.

Abstract: An apparatus, system and technique selectively eliminates the noxious signal components in a neuronal signal by creating an interfering electrical signal that is tuned to a given frequency corresponding to the oscillatory pattern of the noxious signal, resulting in a modified neuronal signal that substantially reproduces a normal, no-pain neuronal signal. The disclosed system and technique of pain relief is based on the hypothesis that the temporal profile of pain signals encodes particular components that oscillate at unique and quantifiable frequencies, which are responsible for pain processing in the brain.

Abstract: Devices, systems, and methods can be used for the closure of surgical wounds. For example, surgical wounds can be closed using magnetic closure devices rather than the conventional methods of using sutures, clips, or staples. Additionally, in some implementations the magnetic closure devices provided herein are delivered laparoscopically or endoscopically via a vacuum catheter.

Abstract: A neuronal tissue-machine interface apparatus includes an array of magnetically-responsive switches positioned in close proximity or contact to neuronal tissue of a human subject, wherein a magnetic environment of the plurality of magnetically-responsive switches varies along the array, and an antenna that is electrically connected to the array, wherein a subset of the magnetically-responsive switches respond to electromagnetic energy received by the antenna, and wherein the response of the subset of the magnetically-responsive switches includes modulation of an electrical current conducted by the subset of the magnetically-responsive switches.

Abstract: A pulsed electromagnetic field (PEMF) treatment apparatus having electrically-conductive loops arranged within an enclosure to form an array, each of the electrically-conductive loops having a generally circular circumference with one or more indentations aligned with a corresponding indentation of an adjacent electrically-conductive loop, where PEMF signals are generated through the array of electrically-conductive loops based on proximity detection conducted by a corresponding wireless device.

Abstract: The present invention provides an energy emission device comprising: one or a plurality of energy emitters for emitting at least one type of energy selected from the group consisting of an electromagnetic wave or an electromagnetic stimulation, an elastic wave, an oscillatory wave and heat to at least one position of a subject selected from the group consisting of the brain, the spinal cord, the cerebrospinal fluid or the flow passage thereof and the brain cell interstitial fluid or the flow passage thereof; an energy controller for controlling an amount of energy emitted from the energy emitters; and a sensor for obtaining information relating to wakefulness and/or a sleeping state of the subject, in which the energy controller controls the amount of energy emitted depending on the information relating to the wakefulness and/or the sleeping state.

Abstract: Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.

Abstract: The present method and system provides for the clinical application of neurostimulation and/or neuromodulation to a patient. The method and system includes receipt and acquisition of patient data, processing of that data relative to one or more known data sets, and determination of a good-fit trigger specific treatment protocol. The method and system provides for application of the protocol to the patient, including delivery of neuromodulation and biofeedback. Based thereon, the method and system re-iterates the goodness of fit determination for further treatment to the patient.

Abstract: The present invention provides methods and compositions for the remote control of cell function based on the use of a magnetic field to excite paramagnetic nanoparticles targeted to specific cell types. The cell type of interest expresses an ion channel wherein excitation of the paramagnetic nanoparticles results in a physical change that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject.

Abstract: A portable LED-laser biomagnetic waves therapy device including a body portion, a head portion, a plurality of magnets, a plurality of LED lights, a laser and a power mechanism. The head portion is attachable to an end of the body portion. The plurality of magnets is mounted to at least one of the body portion and the head portion. The plurality of LED lights is mounted to at least one of the body portion and the head portion. The laser is mounted to at least one of the body portion and the head portion. The power mechanism is operably attached to the plurality of LED lights and the laser.

Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

Abstract: Disinfecting floor mats may be achieved by a variety of systems, processes, and techniques. In one general implementation, a disinfecting floor mat may include a UV LED array, a base, and a transparent cover. The UV LED array may have a top surface, a bottom surface, a perimeter and include multiple UV-emitting LEDs. The base may be configured to receive the UV LED array. The transparent protective cover may include a top surface of an encapsulating sheet for encapsulating the array or a top surface of a non-encapsulated protective sheet, the cover comprised of polyurethane and having substantial strength to withstand a person standing directly thereon with shoes on. The LED array is adapted to irradiate at least a portion of a bottom surface of a shoe positioned on the protective cover.

Abstract: This disclosure includes a method for pushing an active agent into a patient's ear via the device. The agent can be pushed to a treatment site.

Abstract: Combined methods for treating a patient using time-varying magnetic field are described. The methods include generating a time-varying magnetic field and applying the magnetic field to muscle fibers, neuromuscular plates, or peripheral nerves innervating muscle fibers within the body region of the patient such that a muscle is caused to contract. The treatment methods include generating optical waves and applying the optical waves to the body region of the patient to heat a target biological structure of the patient. The methods include providing an applicator housing a coil to generate the time-varying magnetic field and an optical waves generating device to generate the optical waves and attaching the applicator to the patient via a belt.

Abstract: Provided are a pharmaceutical composition for preventing or treating sensorineural hearing loss or tinnitus including platelet-rich plasma, and a method of preventing or treating sensorineural hearing loss or tinnitus using the same.

Abstract: Methods for treating a patient using time varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

Abstract: In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

Abstract: Methods for treating a patient using time varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

Abstract: Methods for treating a patient using time varying magnetic field are described. The treatment methods combine various approaches for aesthetic treatment. The methods are focused on enhancing a visual appearance of the patient.

Abstract: A device for magnetic stimulation of body regions, including at least one magnetic coil connected to a stimulator which has a power element for generating electrical impulses to be applied to the at least one magnetic coil, so that the generated magnetic field can be induced in the body region, wherein a detection unit is provided for detecting metal elements within the body region. A measuring device is provided for detecting the electrical power received by the magnetic coil and a comparison device is provided for comparing the power with a predetermined limit value, the detection unit is connected to the stimulator, and the comparison unit is designed to automatically switch off the stimulator or reduce the power of the stimulator or of the power element of the stimulator in the event of the predetermined limit value being exceeded.

Abstract: To provide a magnetic health device capable of making a variable magnetic field to effectively act. The magnetic health device includes a magnet 12 magnetized along a rotation direction, a first rotation mechanism 13 which rotates the magnet 12 around a rotation shaft 31 of the magnet 12, a second rotation mechanism 14 which rotates the magnet 12 around an orthogonal axis direction of the rotation shaft 31 of the magnet 12, and a support means 15 for supporting the magnet 12, the first rotation mechanism 13 and the second rotation mechanism 14 with respect to a human body.

Abstract: Provided is a magnetic stimulation device, which does not feel hot to the user. The magnetic stimulation device (1) comprises: a contact plate (2) to be disposed near the user's head; an exciting coil (3) to be held above the contact plate (2); a casing (4), which covers at least the upper side of the exciting coil (3), in which openings (17, 18) are provided above the center of the exciting coil (3) winding, and in which a gap that is open on the outside of the exciting coil (3) is formed between the casing and the contact plate (2); and a suction fan (5) for drawing out air between the contact plate (2) and the casing (4) from the openings (17, 18) of the casing (4).

Abstract: A method for communicating with devices may include monitoring brain activity of a subject via an EEG monitoring system coupled to the subject. The method also may include detecting a predefined state of brain activity of the subject. Further, based on the detecting the predefined state, the method may include wirelessly transmitting instructions from the EEG monitoring system to the at least one household device to adjust a setting of the at least one household device.

Abstract: This invention relates to devices and methods for the activation of nerve cells and muscles by magnetic induction, and in particular to devices including moving magnets. The devices disclosed may also have other therapeutic, medical and industrial applications.

Abstract: The present disclosure includes methods and devices for a non-invasive treatment of a neurodegenerative disease through a delivery of energy to a target nervous tissue, such as a vagus nerve of a patient. Such energy can be applied to the patient to generate an electrical impulse. The electrical impulse can be modulated to increase an activity of an anti-inflammatory cytokine in the patient to inhibit inflammation and treat the neurodegenerative disease. Such stimulation can bring about a reduction of neuro-inflammation in some patients suffering from one or more conditions, such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis, postoperative cognitive dysfunction, or postoperative delirium.

Abstract: The disclosed examples relate to various implementations of a micro-light emitting diode upon which is built a controllable variable optic to provide a chip-scale light emitting device. An example of the controllable variable optic described herein is a controllable electrowetting structure having a leak-proof sealed cell with a first fluid having a first index of refraction and a second fluid having a second index of refraction. The controllable electrowetting structure may be integrally formed on or in a substrate or semiconductor material associated with the micro-light emitting diode in alignment with one or more of the light emitting diodes of the micro-LED device to provide a controllable lighting distribution.

Abstract: A coil device for transcranial magnetic stimulation treatment, that generates an overcurrent uniformly across a wide range inside the head of a patient. The coil device includes a winding frame and a coil. A cylindrical surface of the winding frame has: an inner surface section arranged near the cranial surface during use; and an outer surface section forming a convex curved surface protruding towards the outside of the cylindrical surface, relative to a first direction parallel to a neutral axis and a second direction orthogonal to the first direction. The neutral axis draws a convex curve.

Abstract: The present invention describes methods and devices comprising magnetic, radio frequency burst, and light stimulation to modulate muscle contraction. The magnetic stimulation may be delivered to the muscle using one or more coils that is placed transcutaneously. The methods and devices are useful to treat a number of conditions or disease conditions, including for example, gastroesophageal cramps and sphincter leakage.

Abstract: A semantic based document editor is provided. An application such as a document processing application displays previews of a document. The previews include semantic styles. In response to a selection of one of the previews, a semantic style associated with the selected preview is applied to a section of the document. The semantic style is rendered in the selected preview. A suggestion is displayed on the section. The suggestion identifies the section. The suggestion is also formatted based on the semantic style.

Abstract: The present invention provides a facial treatment device and a system including the treatment device combining light and electromagnetic therapy for facial treatments. The facial treatment device includes a mask base; a plurality of light emitting diodes (LEDs) disposed across an inner side of the facial treatment device; and one or more electromagnetic field producing units, each configured for producing an electromagnetic field located over the periphery of the mask base. The system includes the facial treatment device and a control unit that allows controlling the operation of the LEDs and the one or more electromagnetic field producing units.

Abstract: A method comprises: storing, in a memory of a computing device, (i) a preoperative image of patient tissue obtained using a first imaging modality and registered to a first frame of reference, and (ii) anatomical data defining a plurality of neural tracts in the patient tissue; receiving, at a processor connected with the memory, a location in the first frame of reference for application of a cortical stimulator pad to the patient tissue; receiving, at the processor, a range of influence of the cortical stimulator pad; based on the location and the range of influence, selecting, at the processor, an intersected neural tract from the plurality of neural tracts, a portion of the intersected neural tract being located within the range of influence; and controlling, at the processor, the display to render the preoperative image, the location and the intersected neural tract according to the first frame of reference.

Abstract: Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.

Abstract: One embodiment involves modifying neural transmission patterns between neural structures and/or neural regions in a noninvasive manner. In a related exemplary method, sound waves are directed toward a first targeted neural structure and characteristics of the sound waves are controlled at the first target neural structure with respect to characteristics of sound waves at the second target neural structure. In response, neural transmission patterns modified to produce the intended effect (e.g., long-term potentiation and long-term depression of the neural transmission patterns). In a related embodiment, a transducer produces the sound for stimulating the first neural structure and the second neural structure, and an electronically-based control circuit is used to control characteristics of the sound waves as described above to modify the neural transmission patterns between the first and second neural structures.

Abstract: The present disclosure relates to an electron generation apparatus including a discharge pin module provided with a support plate, discharge pins coupled to the support plate, and an elastic connection element electrically connecting a group of discharge pins, a discharge plate placed facing the discharge pins, a support structure positioned at an opposite side to the discharge plate with the support plate interposed between, and provided with a coupling plate to which the discharge pin module and the discharge plate are detachably coupled, and a circuit module provided with a main board positioned apart from the coupling plate at an opposite side to the discharge pin module with the coupling plate interposed between and distribution processing boards connected to the main board to apply individual high-voltage high-frequency pulsed power to the group of discharge pins.

Abstract: A Transcranial Magnetic Stimulator (TMS) is used by a patient to treat a variety of human disorders including migraine headaches. The device has an electronic device to charge a capacitor to a high voltage which creates a high current in a magnetic coil which produces an intense magnetic pulse applied to the patient's head for treatment of migraine headaches or to other patient body parts to treat other disorders. The TMS may be reprogrammed remotely over the Internet to add additional pulses or additional time that the patient may use the TMS, during which time the TMS would continue to function. The data in the TMS may be sent over the Internet to the patient's physician and/or to a monitor to send the data to the company that manufactured the TMS.

Abstract: Device and method for generating brief strong current pulses in a coil for generating magnetic field pulses which according to the electromagnetic induction principle induce stimulation currents in the body tissue triggering an action potential of the nerve and/or muscle cells, where the coil is positionable close to the body tissue to be stimulated so that its magnetic field passes through the body tissue, and where the device comprises a power generating unit that can generate a freely selectable temporal course of the current through the coil during the current pulse.