Absorbent Patch For Fluid Analysis Patents (Class 600/362)
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Patent number: 11857313Abstract: A system 100, 200 for sensing one or more analytes in a first biofluid and a second biofluid and methods of using said system. The system 100, 200 may include a first subsystem 102, 200a, 200b with a first sensor 120, 122, 220, 222 for sensing a first analyte in the first biofluid and a second subsystem 104, 200b, 200c with a second sensor 124, 126, 222, 224 for sensing a second analyte in the second biofluid. The second analyte may be the same as or different from the first analyte and the second biofluid may be different from the first biofluid. In an embodiment, the first biofluid is a non-sweat biofluid and the second biofluid is sweat. The system 100, 200 may be used to detect lag time for measuring an analyte in one of the biofluids.Type: GrantFiled: September 11, 2018Date of Patent: January 2, 2024Assignee: University of CincinnatiInventor: Jason C. Heikenfeld
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Patent number: 11832801Abstract: Provided herein are methods of detecting and measuring disease-associated analytes such as proteins and antibodies in a sweat sample. Also provided are methods of determining and monitoring the disease state or physiological condition of a subject using small sweat samples.Type: GrantFiled: July 11, 2017Date of Patent: December 5, 2023Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Benjamin Katchman, Karen Anderson, Jennifer Blain Christen
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Patent number: 11806163Abstract: Embodiments herein include testing articles to assess hydration of a test subject. The testing articles can include a carrier portion having a porous medium through which a fluid of the test subject moves. The carrier portion can include a first end and a second end opposite the first end. The testing articles can include a first chemical composition disposed in the porous medium that reacts with chloride ions to produce a first color change. The testing articles can include a wick that is in direct contact with the first end of the carrier portion to allow the transfer of the fluid from the wick to the carrier portion. The testing articles can include a fill indicator element in direct contact with the second end of the carrier portion to allow the transfer of the fluid from the carrier portion to the fill indicator element. Other embodiments are also included herein.Type: GrantFiled: October 9, 2019Date of Patent: November 7, 2023Assignee: Inter.mix, Inc.Inventor: Cydney Einck
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Patent number: 11419549Abstract: A deep body thermometer includes an upper exterior body that is made of a foamed material of closed cells or semi-closed cells having waterproof properties and is formed in a substantially hat-like shape in side view, a lower exterior body that has a peripheral edge in close contact with the upper exterior body, a sticking member that has adhesiveness and one surface of which is stuck to an outer side surface of the lower exterior body, and a wiring substrate that is accommodated in a space defined by the upper exterior body and the lower exterior body. The upper exterior body includes stress relieving portions that extend in the direction intersecting with the direction in which stress generated by external force acts and are smoothly curved with respect to the direction in which the stress acts so as to relieve the stress.Type: GrantFiled: May 14, 2019Date of Patent: August 23, 2022Assignee: MURATA MANUFACTURING CO., LTD.Inventor: Toru Shimuta
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Patent number: 11382606Abstract: The application relates to a chemical monitoring system comprising a skin patch for detecting an analyte in perspiration and a processor adapted to receive parameter data and to return an output indicative of a presence of an analyte in a subject's body based on the parameter data. The skin patch (100) includes a first layer (105) permeable to perspiration; a second layer (110) coupled to the first layer, the second layer being adapted to receive the perspiration; wherein a property of the second layer changes upon receiving the analyte; an electrical detector coupled to the second layer, adapted to detect parameter data indicative of the property of the second layer; and a flexible electronic circuit (140) coupled to the second layer, comprising a readout circuit for reading parameter data from the electronic detector and a transmitter adapted to transmit the parameter data to a processor.Type: GrantFiled: December 16, 2016Date of Patent: July 12, 2022Assignee: TFM Inventions LimitedInventors: Ewan Findlay, Sara Murray
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Patent number: 10835214Abstract: Disclosed are a support body, a body fluid collection set, and a body fluid collection method that can easily support a body fluid collection sheet even by a non-physician. The support body 1 includes a first sheet 10 having an adhesive surface 12 for adhering the body fluid collection sheet 30, and a second sheet 20 adhered to the first sheet 10. The adhesive surface 12 of the first sheet 10 is adhered to the body fluid collection sheet 30 so that the first sheet 10 is separated from the skin 40 and the body fluid collection sheet 30 is peeled off from the skin 40. Thereafter, the second sheet 20 is superposed on the adhesive surface 12, and the body fluid collection sheet 30 is supported on the support body 1.Type: GrantFiled: August 29, 2017Date of Patent: November 17, 2020Assignee: SYSMEX CORPORATIONInventors: Seiki Okada, Yasuhito Ohnishi
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Patent number: 10792019Abstract: Disclosed are a support body, a body fluid collection set, and a body fluid collection method that can easily support a body fluid collection sheet even by a non-physician. The support body 1 includes a first sheet 10 having an adhesive surface 12 for adhering the body fluid collection sheet 30, and a second sheet 20 adhered to the first sheet 10. The adhesive surface 12 of the first sheet 10 is adhered to the body fluid collection sheet 30 so that the first sheet 10 is separated from the skin 40 and the body fluid collection sheet 30 is peeled off from the skin 40. Thereafter, the second sheet 20 is superposed on the adhesive surface 12, and the body fluid collection sheet 30 is supported on the support body 1.Type: GrantFiled: August 29, 2017Date of Patent: October 6, 2020Assignee: SYSMEX CORPORATIONInventors: Seiki Okada, Yasuhito Ohnishi
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Patent number: 10506968Abstract: The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.Type: GrantFiled: April 30, 2018Date of Patent: December 17, 2019Assignees: Eccrine Systems, Inc., University of CincinnatiInventors: Jason Heikenfeld, Jacob A. Bertrand, Michael Brothers, Andrew Jajack
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Patent number: 10028685Abstract: A sensing device having a first and second opening, a first semipermeable membrane having a first surface and a second surface, and a second semipermeable membrane having a third and fourth surface, a ketone body sensor, and a void. The first opening is juxtaposed to the first surface and the second opening is juxtaposed to the third surface. The space between the first and second openings is the void and wherein the ketone body sensor is positioned within the void. Gasses may permeate through the first opening and into the void to contact the sensor and exit the void through the second opening.Type: GrantFiled: March 16, 2016Date of Patent: July 24, 2018Inventor: Stephen DeTurk
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Patent number: 9131893Abstract: A health monitoring system, and methods of use and manufacture thereof are disclosed. The health monitoring system may include a computing system and a diagnostic test coupled to a diaper. The diagnostic test may include one or more sensors configured to produce a visual indication of one or more analytes contained in a sample produced by a subject. The diagnostic test may include a machine-readable code. The computing system may be configured to read the machine-readable code to allow an application running on the computing system to automatically perform at least one task related to a production of a data point based on the visual indication. The health monitoring system may aid in identifying a potential abnormal health condition of the subject by providing automatic longitudinal analysis of analytes contained in samples produced by the subject over a period of time.Type: GrantFiled: October 28, 2013Date of Patent: September 15, 2015Assignee: Pixie Scientific, LLCInventors: Yaroslav Faybishenko, Boris Faybishenko
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Patent number: 8946501Abstract: A liquid leakage detection system requiring no power supply from an outer source and configured to be relatively simple and moderate in price. A liquid leakage detection system (10) including an infusion tube (11), a syringe needle (12) coupled to the infusion tube (11), an absorbent element (16) adapted to be placed in the vicinity of a point (12a) of the syringe needle (12) to be pricked through a patient skin and a sensor unit (14) located on an upper side or within the absorbent element (16).Type: GrantFiled: August 13, 2010Date of Patent: February 3, 2015Assignee: Aqua Power System, JapanInventors: Naoyuki Kamatani, Tadashi Ishikawa, Yoshiaki Hasebe
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Publication number: 20150025347Abstract: A lateral flow device for testing a bodily fluid, such as urine, blood, mucous, saliva, etc., is provided. The lateral flow device is configured to be attached to an absorbent article via an attachment mechanism located on the lateral flow device or the absorbent article. The lateral flow device includes a chromatographic medium (e.g., porous membrane) that defines a detection zone that provides a signal indicative of the presence or absence of the analyte. The device may also include a control zone that provides a signal indicative of whether a sufficient amount of bodily fluid has been provided and tested. Regardless of its specific configuration, the lateral flow device is configured to be attached onto the absorbent article to provide a user or caregiver with rapid information about a health condition. For example, the device may be attached onto a diaper to provide information about the presence of enzymes or other compounds often encountered with a patient having a urinary tract infection.Type: ApplicationFiled: August 4, 2014Publication date: January 22, 2015Inventor: Xuedong Song
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Publication number: 20140357971Abstract: The present invention discloses a tear analyzing strip (TAS) for measuring dry eye syndrome in a patient. The TAS comprises an elongated body comprising a proximal portion and a distal portion interconnected by a main longitudinal axis. The distal portion comprises at least one tear channel comprising at least one tear receiving portion in fluid communication with an eye of the patient such that tears sampled from the eye into the channel. Reagent pads disposed along the length of the distal portion. The reagent pad is in fluid communication with the tear channel such that tears flow through the tear channel towards the reagent pads, thereby progressively wetting the reagent pads. Each of the reagent pads comprises an effective measure of a reagent capable of biological, physical, or chemical activation by the tears or a component thereof and of providing a visible indication of the activation.Type: ApplicationFiled: November 29, 2012Publication date: December 4, 2014Inventors: Eran Eilat, Robert David
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Patent number: 8901366Abstract: In accordance with one embodiment of the present disclosure, a method for quantitatively or semi-quantitatively determining the volume of a test sample of urine is provided. The method includes contacting the test sample with a fluidic medium of a lateral flow device having a volume indicator disposed thereon and determining the volume of urine in the test sample based on the distance traveled by the volume indicator along the fluidic medium, the distance traveled by the volume indicator corresponding to the volume of urine in the test sample.Type: GrantFiled: December 14, 2007Date of Patent: December 2, 2014Assignee: Kimberly Clark Worldwide, Inc.Inventors: Xuedong Song, RameshBabu Boga, Ning Wei
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Publication number: 20140296667Abstract: A device (1) is provided that is configured to indicate the presence or absence of one or more biological entities in a biological sample. The device comprises a sampling portion (11), the sampling portion comprising flexible material adjustably conformable to a part of a human or animal body, at least a portion of the sampling portion being absorbent and configured to receive a biological sample directly from the body; and a test portion (12) in fluid engagement with the sampling portion, the test portion comprising one or more test zones (14). The sampling portion and test portion are configured such that at least a portion of the sample received by the sampling portion is transferable to the test portion such as to contact one or more of the test zones, and wherein each test zone is configured to indicate the presence or absence of one or more biological entities in the sample.Type: ApplicationFiled: January 27, 2011Publication date: October 2, 2014Applicant: RESPIRIO PTY LTDInventors: Steven David Dahl, Sean Andrew Parsons, Jennifer Maschmann, Kon Euan Gerard Wong, Tim Ian Spink, Stephen Robert Wilson
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Patent number: 8758311Abstract: A transdermal product delivery patch comprises a reservoir containing a product for delivery to a patient; means for affixing the patch to the skin of the patient; and manually operable means for actuating an extensor mechanism to exert pressure on the reservoir and thereby expel the product towards the skin. The patch may be supplied with the extensor mechanism held in a strained configuration and the manually operable means may be a restraint such as a peelable layer that can be removed to allow the extensor mechanism to move using stored energy towards a rest configuration. The extensor mechanism may be a ring of resilient material that is pre-stretched radially inwards so that, upon release, it stretches the reservoir radially outwards. The patch may be supplied with the extensor mechanism in a rest configuration and the manually operable means may deform it in a predefined manner into a strained configuration.Type: GrantFiled: August 1, 2011Date of Patent: June 24, 2014Assignee: Nemaura Pharma LimitedInventor: Dewan Fazlul Hoque Chowdhury
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Patent number: 8747316Abstract: An in vivo component measurement method allowing how long a high concentration state of a measurement target component continues in an organism to be grasped is provided. In this in vivo component measurement method, a value relating to an amount of a measurement target component in tissue fluid extracted for 60 minutes or more from an organism on which a treatment for enhancing extraction of tissue fluid has been made is acquired.Type: GrantFiled: January 28, 2011Date of Patent: June 10, 2014Assignee: Sysmex CorporationInventor: Seiki Okada
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Patent number: 8742198Abstract: A dehydration sensor having a stable, printable, buffered-ink composition that enables one to miniaturize the detection zone and permits both buffer and indicator dye to be applied in the same area of a detection zone, without need for a conventional, large buffer pad region. The ink composition includes a weak polymeric base as its primary buffering agent.Type: GrantFiled: December 1, 2010Date of Patent: June 3, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Ning Wei, Xuedong Song, Ronnie L. Phillips
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Patent number: 8704035Abstract: A dehydration sensor having a stable, printable, buffered-ink composition that enables one to miniaturize the detection zone and permits both buffer and indicator dye to be applied in the same area of a detection zone, without need for a conventional, large buffer pad region. The ink composition includes a weak polymeric base as its primary buffering agent.Type: GrantFiled: December 1, 2010Date of Patent: April 22, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Ning Wei, Xuedong Song, Ronnie L. Phillips
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Publication number: 20140066734Abstract: In a first embodiment, electrodes are coupled to a surface at first, second, and third locations, the first location being further from the third location than from the second location. Impedance is measured at distinct frequencies between pairs of the electrodes. As a result, impedance is measured at differing regions below the surface, one region being deeper below the surface than the other region. In a second embodiment, a microfluidic device carries out an analysis. The analysis may be within a flexible patch adhered to a surface, or may be in a solid device implanted in a body of liquid surrounded by tissue. The analysis may involve pumping a fluid or may involve drawing an analyte electrophoretically through a microfluidic channel.Type: ApplicationFiled: August 30, 2013Publication date: March 6, 2014Applicant: Proteus Digital Health, Inc.Inventor: Mark Zdeblick
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Publication number: 20140051951Abstract: The present invention relates to the analysis apparatus capable of collecting the body fluid such as urine or blood, for embodiment urination and measuring or calculating the specific constituent from the collected body urine, and the apparatus for collecting body fluid capable of using by connecting to the analysis apparatus and its related article, in which the apparatus for collecting and analyzing for the body fluid of a patient consists of the body fluid collecting part and the collecting part case, the apparatus for collecting body fluid consists of the body fluid collecting part, the total tube and adapter, the collecting part is constructed with the absorbing tube, the sensor tube, the cleansing tube and the passage and is attachable/detachable connected to the collecting part, a diaper and pants exclusive for a patient are provided as the related article such that it is convenient to possess and has effects in the urination having no relations to the intention of a patient or in case of unable to useType: ApplicationFiled: July 18, 2013Publication date: February 20, 2014Inventor: Kyoung-Hun KIM
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Publication number: 20140018654Abstract: The present invention is directed toward a wound dressing comprising a foam body made of polyvinyl acetal material treated with a plurality of colored biocidal dyes with at least one of the dyes being gram positive and at least one of the dyes being gram negative to dye the body a distinct color. The body has at least one planar surface and ranges from about 1 mm to about 3 mm in thickness and has an outer adhesive section secured to the body. The body when placed in contact with an infected wound site changing color.Type: ApplicationFiled: July 12, 2012Publication date: January 16, 2014Inventor: Thomas J. Drury
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Publication number: 20130267807Abstract: Apparatus for eliciting a blood sample comprises: a housing; a shaft mounted within the housing; an aperture in the housing, the aperture being configured to receive a part of a user; a member rotatably mounted on the shaft; a lancet protruding from one position at an edge of the member, and a blood collection part located at a second, different position at the edge of the member. The apparatus is configured such that: when the member is in a first rotational position the lancet is shielded by the housing, when the member is in a second rotational position the lancet is operable to lance the part of the user received at the aperture, and when the member is in a third rotational position the blood collection part is presented such as to receive blood from the part of the user received at the aperture.Type: ApplicationFiled: July 7, 2011Publication date: October 10, 2013Applicant: Sanofi-Aventis Deutschland GmbHInventors: Ross MacArthur, Frank Richter
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Publication number: 20130261409Abstract: Various methods, devices and systems for patch based physical, physiological, chemical, and biochemical sensors that diagnose and monitor disease states are described. The patch based sensors provide a panel of specific analyte parameters that determine one or more physiological conditions and/or the level of healing progression of a wound. The use of such analyte panels in local or remote monitoring of parameters related to various disease states is also described.Type: ApplicationFiled: November 30, 2010Publication date: October 3, 2013Inventors: Srikant Pathak, David N. Edwards
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Publication number: 20130197334Abstract: The invention concerns a Biodetector with a functionalised surface for isolating molecules or cells from the human body. In order to improve a Biodetector of the type mentioned above such that the functionalised surface of the Biodetector or there upon enriched molecules or cells are exposed to a lower abrasion, and the biocompatibility of the Biodetector is improved, the Biodetector is designed to remove a fluid from the human body and absorb it into an inner space of the Biodetector, wherein the functionalised surface is oriented to the inner space of the Biodetector.Type: ApplicationFiled: March 15, 2011Publication date: August 1, 2013Applicant: GILUPI GMBHInventors: Ekkehardt Weber, Robert Niestroj
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Patent number: 8454550Abstract: An apparatus is disclosed for detecting moisture, which is intended for the use in an apparatus for monitoring an access to a patient for a device by means of which a fluid is conducted to and/or removed from a patient via a hose line, in particular for monitoring the vascular access during an extracorporeal blood treatment, wherein blood of a patient is removed from the patient via an arterial hose line, which has an arterial puncture cannula, and is conducted back to the patient via a venous hose line, which has a venous puncture cannula. The apparatus for detecting moisture is designed as a pad which is made of a flexible material and is to be applied onto the patient's skin and which comprises an upper side facing away from the patient's skin and a lower side facing the patient's skin. The pad comprises an opening for the passage of fluid, in particular blood, and a moisture sensor having contact elements for the connection of the same.Type: GrantFiled: February 11, 2010Date of Patent: June 4, 2013Assignee: Fresenius Medical Care Deutschland GmbHInventors: Christoph Koenig, Alexander Schroers, Andreas Wuepper, Alexander Heide, Juergen Klewinghaus
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Publication number: 20130096400Abstract: A device (1) is provided that is configured to indicate the presence or absence of one or more biological entities in a biological sample. The device comprises a sampling portion (11), the sampling portion comprising flexible material adjustably conformable to a part of a human or animal body, at least a portion of the sampling portion being absorbent and configured to receive a biological sample directly from the body; and a test portion (12) in fluid engagement with the sampling portion, the test portion comprising one or more test zones (14). The sampling portion and test portion are configured such that at least a portion of the sample received by the sampling portion is transferable to the test portion such as to contact one or more of the test zones, and wherein each test zone is configured to indicate the presence or absence of one or more biological entities in the sample.Type: ApplicationFiled: January 27, 2011Publication date: April 18, 2013Applicant: RESPIRIO PTY LTDInventors: Steven David Dahl, Sean Andrew Parsons, Jennifer Maschmann, Kon Euan Gerard Wong, Tim Ian Spink, Stephen Robert Wilson
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Publication number: 20130053668Abstract: The present invention relates to a kit for detecting blood sugar. The present invention also relates to a method for detecting blood sugar according to the kit. The kit comprises an adhesive sweat absorption device comprising: a sweat absorption patch for absorbing sweat of a subject; a detector layer for generating electronic signals according to the sugar level of sweat absorbed by the sweat absorption patch; a signal amplifier for amplifying electronic signals generated by the detector layer; a wireless transmitter for sending amplified electronic signals generated by the signal amplifier to a remote signal receiver, in order to calculate blood sugar level; and a power supply device for supplying electric power required for operation of detector layer.Type: ApplicationFiled: August 24, 2012Publication date: February 28, 2013Applicant: COMPOSE ELEMENT LIMITEDInventor: Tsu-Tai Lin
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Publication number: 20130006080Abstract: A living body component analyzing method that can accurately analyze a measurement target component even when the subject perspires is provided. A living body component analyzing method for analyzing a component contained in a tissue fluid extracted from the skin of a subject includes: a step of subjecting part of the skin of the subject to a process of facilitating extraction of the tissue fluid; a step of collecting a measurement target component from the skin subjected to the facilitation process; a step of collecting a first auxiliary component from the skin subjected to the facilitation process; a step of collecting a second auxiliary component contained in perspiration from the skin excluding the part subjected to the facilitation process; and a step of analyzing the measurement target component based on the collected measurement target component, the first auxiliary component and the second auxiliary component.Type: ApplicationFiled: September 13, 2012Publication date: January 3, 2013Applicant: PANASONIC CORPORATIONInventors: Seiki OKADA, Yoshihiro ASAKURA, Toshiyuki SATO, Kei HAGINO, Junko KOJIMA
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Patent number: 8235930Abstract: A fluid loss detection device for dressings at pre-existing port sites, catheter sites, operative sites, ostomy sites, drain sites, line sites such as those utilized in hemodialysis, wound sites, or other areas for which monitoring of fluid or blood loss is medically indicated. The detection device includes a patch having a primary loop circuit and an early warning alarm circuit loop. In one embodiment, closure of the early warning alarm circuit loop activates an alarm. The alarm may be connected directly to the patch and sound locally or may be activated remotely via radio transmission. The alarm may alternatively cause a medical device such as a hemodialysis system to shut down.Type: GrantFiled: October 28, 2009Date of Patent: August 7, 2012Inventor: Kenneth Shawn McCall
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Publication number: 20120165626Abstract: Devices, methods, and kits for measuring or otherwise evaluating the concentration of one or more analytes in a body fluid are described. The devices, methods, and/or kits may be non-invasive. In some variations, a method for measuring the concentration of an analyte in sweat of a subject may comprise contacting a colorimetric membrane with a skin surface of the subject so that the membrane collects a volume of sweat from the skin surface, and analyzing the colorimetric membrane to determine the concentration of the analyte in the collected volume of sweat.Type: ApplicationFiled: July 1, 2010Publication date: June 28, 2012Inventors: Finkelshtein V. Irina, James W. Moyer, Russell O. Potts, Burton H. Sage, Robert J. Shartie, Donald R. Wilson, Bruce D. Wong
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Patent number: 8188332Abstract: The invention refers to a disposable cover for use in an incubator for premature infants comprising a moisture-pervious surface layer and a preferably moisture-impervious back sheet, wherein the total weight of the cover before use is communicated to the caregiver by indication on said cover, a label accompanying said cover or on the package for said cover. The cover may further be provided with a wetness indicator.Type: GrantFiled: December 22, 2006Date of Patent: May 29, 2012Assignee: SCA Hygiene Products ABInventors: Ingemar Fernfors, Anna-Gerd Doverbo
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Publication number: 20120095308Abstract: Provided is a strip-shaped detector that detects an analyte in a liquid sample. The detector includes a collecting member that directly collects a liquid sample from a living organism, a holding member that holds a labeling reagent binding specifically to the analyte in a state where the labeling reagent can move along with the movement of the liquid sample, a detecting member to which a detection reagent is immobilized which captures a complex of the analyte and the labeling reagent by binding specifically to the analyte, an absorbing member that can absorb the liquid sample, and a liquid-impermeable supporting member, wherein the respective members are arranged on the supporting member in the longitudinal direction of the detector so that the liquid sample moves through the inside of these members, and the collecting member includes a protruding portion sticking out of the supporting member at the upstream side in the movement direction of the liquid sample.Type: ApplicationFiled: April 9, 2009Publication date: April 19, 2012Inventors: Masayuki Higuchi, Yuuichi Nakano, Nahoko Suzuki, Miki Tanimoto, Kouhei Yamashita
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Patent number: 8084268Abstract: A substrate is filled with a reagent that presents a stable free radical character, and that is capable of producing a visible reaction in the presence of at least one free radical scavenger analyte of the skin.Type: GrantFiled: February 27, 2006Date of Patent: December 27, 2011Assignee: L'OrealInventors: Francis Pruche, Quang Lan Nguyen, Jean-Pascal Hirt
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Patent number: 8053625Abstract: Wetness indicators may include alarm devices that are designed to assist parents or attendants in identifying a wet diaper condition early on. These devices produce either a visual or an audible signal. Many of these devices rely on electronics, which may increase the expense of the absorbent article. Further, electronic devices rely on electrical sources and may be prone to failure if not utilized for an extended period of time.Type: GrantFiled: December 14, 2006Date of Patent: November 8, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Davis Dang H. Nhan, Andrew M. Long, Shirlee A. Weber, Darold D. Tippey, Meghan E. Collins
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Publication number: 20110236322Abstract: Example embodiments of the present invention include various compositions that include a pH modifier composition and/or a buffering capacity modifier composition. In some examples, the pH modifier compositions include a dose of pH modifier to raise the pH in a patient's mouth from about 1 to about 2 pH levels. The compositions are then incorporated into various confections for oral ingestion or application that allow a patient to easily use the composition with the pH and/or buffering capacity modifiers. For example, compositions with the pH and/or buffering capacity modifiers can be incorporated within chewing gum, tablets, lozenges, breath strips, hard candy, oral sprays, and other confections. Another embodiment of the invention includes a testing device to test the pH and buffering capacity within a patient's mouth.Type: ApplicationFiled: March 25, 2011Publication date: September 29, 2011Applicant: CAO Group, Inc.Inventors: Steven D. Jensen, Densen Cao
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Publication number: 20110166432Abstract: A diagnostic agent is delivered intravaginally or to the interlabial space by positioning an interlabial device, such as an absorbent pad, between the labia. The pad is retained between the labia to deliver an active agent, or allow a reaction with a diagnostic agent. Alternatively, the pad is applied after the diagnostic agent is administered, to help reduce discomfort to the subject, or loss of the diagnostic agent. The active agent may be carried by the pad itself, or in an intravaginal extension of the pad, or separately in a suppository or other dosage form. In particular examples, the pad has a smaller minor portion superimposed on a larger major portion, and the smaller minor portion is inserted as a leading edge between the labia of the subject to facilitate interlabial insertion. In another example, the pad is placed interlabially after insertion of an agent.Type: ApplicationFiled: January 12, 2011Publication date: July 7, 2011Inventor: William H. Fleming
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Publication number: 20110166433Abstract: A fluid sampling system is disclosed comprising a fluid drawing device and a fluid sampling device. In one embodiment, the fluid sampling device has a base portion having a cannula, a handle, and a ridge extending around at least a portion of an outer surface. A top portion has a flange adapted to engage the ridge to couple the top portion to the base portion. In another embodiment, the fluid sampling device has a base portion having a cannula, a handle, a mounting portion, and a test strip coupled to the base portion at least partially within the mounting portion. In yet another embodiment, the fluid sampling device has a test strip housing for receiving an end of a test strip therein. Extending from an end of the test strip housing is a blunt cannula.Type: ApplicationFiled: February 17, 2011Publication date: July 7, 2011Applicant: GLUCOR SYSTEMS, LLCInventors: Corey Dalebout, Josh Sybrowsky
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Publication number: 20100256064Abstract: A microprotrusion array for use in transport of a material across a biological barrier, wherein said array comprises a plurality of microprotusions composed of a swellable polymer composition.Type: ApplicationFiled: September 29, 2008Publication date: October 7, 2010Inventors: David A. Woolfson, Desmond Ian John Morrow, Anthony Morrissey, Ryan F. Donnelly, Paul A. McCarron
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Patent number: 7781640Abstract: A disposable absorbent article including a wetness sensation member and visible highlighting indicating the presence of the wetness sensation member to facilitate an opportunity for the toilet training of the wearer. The wetness sensation member includes a permeable layer and a flow control layer. Urine deposited on the wetness sensation member can penetrate through the permeable body-facing layer in a z direction away from the wearer to the flow control layer. The flow control layer retards the passage of the urine through the wetness sensation member in the z direction while supporting the movement of the urine in an x-y plane to increase the wetted area contacting the wearer's skin and thereby enhance the wearer's awareness that urination has occurred. The visible highlighting is visible when viewing a body-facing surface of the article and may be associatively correlated with an externally visible marking and/or with the concept of toilet training.Type: GrantFiled: November 17, 2005Date of Patent: August 24, 2010Assignee: The Procter & Gamble CompanyInventors: Mary Elizabeth Davis, Donald Carroll Roe, Patrick Jay Allen, Edward Paul Carlin
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Patent number: 7767876Abstract: A disposable absorbent article including a wetness sensation member and visible highlighting indicating the presence of the wetness sensation member to facilitate an opportunity for the toilet training of the wearer. The wetness sensation member includes a permeable layer and a flow control layer. Urine deposited on the wetness sensation member can penetrate through the permeable body-facing layer in a z direction away from the wearer to the flow control layer. The flow control layer retards the passage of the urine through the wetness sensation member in the z direction while supporting the movement of the urine in an x-y plane to increase the wetted area contacting the wearer's skin and thereby enhance the wearer's awareness that urination has occurred. The visible highlighting is visible when viewing a body-facing surface of the article and may be associatively correlated with an externally visible marking and/or with the concept of toilet training.Type: GrantFiled: October 30, 2003Date of Patent: August 3, 2010Assignee: The Procter & Gamble CompanyInventors: Mary Elizabeth Davis, Donald Carroll Roe, Patrick Jay Allen, Edward Paul Carlin
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Patent number: 7725149Abstract: Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.Type: GrantFiled: June 22, 2005Date of Patent: May 25, 2010Inventors: Thomas A. Peyser, Russell O. Potts, Herbert L. Berman, James W. Moyer, Mikhail A. Kouchnir
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Patent number: 7670289Abstract: A fluid loss detection device for dressings at pre-existing port sites, catheter sites, operative sites, ostomy sites, drain sites, line sites such as those utilized in hemodialysis, wound sites, or other areas for which monitoring of fluid or blood loss is medically indicated. The detection device includes a patch having a primary loop circuit and an early warning alarm circuit loop. In one embodiment, closure of the early warning alarm circuit loop activates an alarm. The alarm may be connected directly to the patch and sound locally or may be activated remotely via radio transmission. The detection device may additionally cause a medical device such as a hemodialysis system to shut down.Type: GrantFiled: August 1, 2007Date of Patent: March 2, 2010Inventor: Kenneth Shawn McCall
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Patent number: 7641612Abstract: A blood loss detection device for a hemodialysis system having a blood intake line, a dialysis machine including a pump, with the dialysis machine in communication with the blood intake line, and a blood return line in communication with the dialysis machine. The detection device includes a patch having an exterior edge and an opening through the patch forming a target for receipt of the return blood line. A slit through the patch extends between the exterior edge and the opening. A primary loop circuit terminates at two ends at the slit. An early warning alarm circuit loop terminates at two ends at the slit. An emergency shut-down circuit loop terminates at two ends at the slit. A modular connector connects the patch to an alarm activated by the early warning alarm circuit and to a switch mechanism activated by the shut-down circuit in order to shut down the dialysis machine and the pump.Type: GrantFiled: January 17, 2006Date of Patent: January 5, 2010Inventor: Kenneth Shawn McCall
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Patent number: 7383072Abstract: A method of sensing the concentration level of at least one particular electrolyte in the sweat fluid of a subject, includes providing a sweat sensor system having sweat fluid absorbing material, measuring apparatus for sensing the electrical conductivity of sweat fluid absorbed by the absorbing material and producing ionic concentration data for said at least one particular electrolyte, and a user interface connected to the measurement apparatus for interpreting the data to a user. The absorbing material is applied to the skin of the subject to cause sweat fluid thereon to be absorbed by the absorbing material whereby the measurement apparatus produces ionic concentration data for the sweat fluid absorbed and the user interface interprets the data for a user.Type: GrantFiled: May 9, 2005Date of Patent: June 3, 2008Assignee: P. J. Edmonson LtdInventors: Peter J. Edmonson, Douglas W. Stoddard
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Patent number: 7365238Abstract: A wearable article comprising a dehydration indicator adapted to measure a urine ionic strength correlated to a specific gravity of the wearer's urine and provide a visible signal when the urine ionic strength reaches a value corresponding to a predetermined threshold of the specific gravity. The wearable article may be a disposable absorbent article. The dehydration indicator may also be comprised in an insert for use with a wearable article. The dehydration indicator may provide qualitative or quantitative information about the ionic strength of the wearer's urine.Type: GrantFiled: February 19, 2002Date of Patent: April 29, 2008Assignee: The Procter and Gamble CompanyInventors: Joseph Raymond Diehl, Donald Carroll Roe, Patrick Jay Allen
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Patent number: 7276041Abstract: A method of alerting medical personnel of a problem during hemodialysis includes providing an active, fail-to-safe site sensor for a fistula needle at an access site during hemodialysis; and automatically alerting medical personnel of a problem during hemodialysis using the active, fail-to-safe site sensor during at least the following: failing of the active, fail-to-safe site sensor; insufficient powering to the active, fail-to-safe site sensor; partial fistula needle dislodging from the access site; and complete needle dislodging from the access site.Type: GrantFiled: November 16, 2005Date of Patent: October 2, 2007Assignee: Bradley Jon Moll, Rodney L. Moll and Ann E. Moll Family TrustInventor: Bradley Jon Moll
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Patent number: 7175430Abstract: The invention relates to deformable, curable or film-forming support materials which contain diagnostically useful additives for locus- and substance-specific intraoral diagnostics, and processes for the preparation of images for intraoral locus- and substance-specific diagnostic purposes, in which diagnostically useful additives are applied to deformable, curable or film-forming support materials containing no diagnostically useful additives, in such a quantity that a diagnostic signal can be observed, the diagnostic result being obtained without a cultivation step.Type: GrantFiled: June 13, 2000Date of Patent: February 13, 2007Assignee: 3M ESPE AGInventors: Oswald Gasser, Rainer Guggenberger, Bernd Gangnus, Ingo Häberlein
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Patent number: 7041057Abstract: A tissue interface device (10) suitable for positioning on or about one or more artificial openings in a biological membrane of an organism and for coupling to a monitor and control unit and a vacuum source. The tissue interface device (10) comprises a housing (100), a sensor channel (130), and a sensor (150). The housing (100) defines an orifice (120), the orifice (120) having an open inlet port (122) on the bottom end (102) of the housing (100) and a distal end (124) that is in fluid communication with the sensor channel (130). The orifice (120) is in fluid communication with fluid that flows from the artificial opening formed in the biological membranes. The sensor channel (130) is for coupling to, and fluid communication therewith, the vacuum source. The sensor (150) is positioned in the sensor channel (130) in a flow path of the fluid for sensing a characteristic of the fluid as it flows out from the artificial opening. The sensor generates a sensor signal representative thereof.Type: GrantFiled: November 17, 2000Date of Patent: May 9, 2006Assignee: SpectRx, Inc.Inventors: Mark L. Faupel, Krishna Kumar, J. David Farquhar, Mark Vreeke, Alan Smith, Michael Hatch, Teresa Woods
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Patent number: 7037262Abstract: The invention relates to attachable body fluid collection devices, each comprising at least one storage structure for, when in use, storing a body fluid sample secreted by a body fluid secreting surface. The or at least one of the storage structure comprises silicon. Particular emphasis is placed on sweat patches and techniques for analyzing sweat.Type: GrantFiled: August 14, 2002Date of Patent: May 2, 2006Assignee: pSiMedica LimitedInventors: Roger Aston, Leigh T Canham