Measuring Or Detecting Nonradioactive Constituent Of Body Liquid By Means Placed Against Or In Body Throughout Test Patents (Class 600/309)
  • Patent number: 10674913
    Abstract: Systems and methods for monitoring of biometric and contextual variables to assist in screening for, quantification of, and prediction of smoking behavior, and for assisting in smoking cessation are described.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: June 9, 2020
    Assignee: Carrot, Inc.
    Inventors: David S. Utley, Allen Jameson, Jennifer Marler
  • Patent number: 10660550
    Abstract: Implantable sensor apparatus and methods of implantation. In one embodiment, a fully implantable, biocompatible sensor is disposed within a cavity or pocket formed within a living being, such that the sensor remains in a desired orientation and placement so as to enhance the performance of the sensor, and mitigate the effects of one or more factors potentially deleterious to the operation of the sensor and the host being. In one implementation, the sensor comprises an implantable biocompatible oxygen-based glucose sensor which is implanted deep within the being's torso tissue proximate the extant fascia, and oriented such that an active detector aspect of the device faces away from the being's skin surface. In one variant, the deep placement, orientation, and construction of the sensor itself cooperate to enhance the performance of the sensor, especially over extended periods of time, with little need for external calibration.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: May 26, 2020
    Inventors: Joseph Lucisano, Jonathan Wilensky, Robert Engler
  • Patent number: 10653349
    Abstract: A diagnostic patch apparatus has a sampling module that includes sampling means for sampling fluid from a patient's skin when the sampling module is placed against the patient's skin, and a sample chamber coupled in fluid communication with the sampling means. The apparatus also has an analysis module that includes a fluid conduit coupled in fluid communication with the sample chamber of the sampling module and a plurality of sensors coupled in fluid communication with the fluid conduit. The apparatus also may have a reader module that includes at least one optical sensor coupled in optical communication with the analysis module, a microcontroller coupled in electrical communication with the at least one sensor of the analysis module, and a wireless communication package coupled in electrical communication with the microcontroller.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: May 19, 2020
    Assignee: International Business Machines Corporation
    Inventors: Emmanuel Delamarche, James L. Hedrick, Minhua Lu, Vince S. Siu
  • Patent number: 10646713
    Abstract: Methods for reducing a risk associated with developing cognitive impairment, including dementia, with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. Sympathetic nerve activity can contribute to several cellular and physiological conditions associated with an increased risk of developing dementia in later life. One aspect of the present technology is directed to methods for improving a patient's calculated risk score for developing dementia. Other aspects of the present technology are directed to reducing a likelihood of developing dementia in patients presenting one or more dementia risk factors in middle age. Renal sympathetic nerve activity can be attenuated to improve a patient's risk of developing dementia. The attenuation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: May 12, 2020
    Inventors: Douglas Hettrick, Gabriel Lazarus
  • Patent number: 10624567
    Abstract: Provided are dermal sensors and dermal sensor applicator sets to insert at least a portion of a dermal sensor into a dermal layer of a subject, as well as methods of making and using the same.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: April 21, 2020
    Inventors: Benjamin Jay Feldman, Hyun Cho, John Charles Mazza
  • Patent number: 10610617
    Abstract: A method for coating a medical implant applies at least one coating to at least one surface of the implant by plasma polymerization. The implant has pores sized in the nanometer range. The method stabilizes the pores. The plasma polymerization is conducted in the presence of a coating gas and oxygen. A coating parameter can be selected so that a rough surface of the implant is coated. An implant includes a membrane having pores sized in the nanometer range. A surface of the implant is at least partially coated with a plasma polymer. The interior of the pores is uncoated.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: April 7, 2020
    Assignees: BIOTRONIK SE & Co. KG, Albert-Ludwigs-Universitat Freiburg
    Inventors: Andreas Bunge, Michael Bergmann, Loic Ledernez, Alexander Borck, Gerald Urban
  • Patent number: 10610140
    Abstract: The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: April 7, 2020
    Assignee: DexCom, Inc.
    Inventors: James R. Petisce, Mark A. Tapsak, Peter C. Simpson, Victoria Carr-Brendel, James H. Brauker
  • Patent number: 10603208
    Abstract: A modular stimulus applicator system and method are disclosed. The system includes a plurality of wirelessly controlled stimulus pods, anchored to a patient's body, and configured to deliver stimulus to the patient's body. The stimulus can be heat, vibration, or electrical stimulus, or any combination thereof. The stimulus pods are controlled by a control station that can include a user-interface through which the patient can control application of the stimulus.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: March 31, 2020
    Inventors: Peter J. Dunbar, Charles Chabal
  • Patent number: 10588533
    Abstract: A bioelectrode component includes an electrode member. The electrode member includes a metal plate, a coupling bar, and a needle part. The metal plate includes a first surface and a second surface opposite to the first surface, and includes an opening formed in the metal plate. The coupling bar extends inward from an inner wall of the opening. The needle part is arranged at a leading end of the coupling bar and protrudes toward the first surface of the metal plate.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: March 17, 2020
    Inventors: Hideaki Sakaguchi, Yoshihiro Ihara
  • Patent number: 10587297
    Abstract: A wireless sensor device capable of constant operation without replacement of batteries. The wireless sensor device is equipped with a rechargeable battery and the battery is recharged wirelessly. Radio waves received at an antenna circuit are converted into electrical energy and stored in the battery. A sensor circuit operates with the electrical energy stored in the battery, and acquires information. Then, a signal containing the information acquired is converted into radio waves at the antenna circuit, whereby the information can be read out wirelessly.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: March 10, 2020
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventor: Jun Koyama
  • Patent number: 10537287
    Abstract: Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices. The sensors may include a body with different configurations for attaching to the implantable device, such as apertures for sutures or fingers for connecting to structures of the implantable device. The sensors may provide data that allow a determination of aortic regurgitation or other information indicative of function of the implantable device and patient health during and after implantation of the device.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: January 21, 2020
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Peter N. Braido, Mina S. Fahim, Steven Frederick Anderl, Jason White, Paul E. Ashworth, Morgan Low, Loell Boyce Moon, Neelakantan Saikrishnan
  • Patent number: 10527663
    Abstract: A forward-backward Kalman filter for estimating phase noise present in a received signal. Both the forward and backward Kalman filters use hard-decision measurements of the received symbols. The phase noise estimate from the forward Kalman filter is used as a coarse phase noise estimate for the backward Kalman filter and vice versa. The final phase noise estimate is an optimal combination of the forward phase noise estimate and backward phase noise estimate.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: January 7, 2020
    Inventor: Mohamed Mansour
  • Patent number: 10524730
    Abstract: Microneedle arrays, methods for fabricating microneedle arrays, medical devices, and methods for operating medical devices are provided. A method for fabricating a microneedle array includes providing a sheet blank of material. Further, the method includes stamping the sheet blank of material with a progression of dies, wherein the material is displaced into the microneedle array. A medical device includes a microneedle array, a base member having a first surface supporting the microneedle array and a second surface, and a flexible wall enclosing a chamber between the flexible wall and the second surface of the base member. The flexible wall is biased toward an extended configuration enclosing a first volume in the chamber. Further, the flexible wall is movable to a depressed configuration enclosing a second volume in the chamber less than the first volume.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: January 7, 2020
    Assignee: Medtronic MiniMed, Inc.
    Inventors: James A. Reitz, Raymond M. Russell, Anthony C. Cannistraci, David Pavell
  • Patent number: 10517892
    Abstract: Methods and devices are provided for reducing a diabetic patient's foreign body immune response, including infusion site-loss and/or occlusion. Such foreign body responses are associated with the treatment of the diabetic patient where the treatment requires subcutaneous implantation of a foreign body, such as a cannula or catheter. In certain embodiments of the invention, a response-inhibiting agent is administered to a patient at the site of cannula/catheter insertion, thereby facilitating delivery of insulin to the diabetic patient and mitigating site-loss and/or occlusion over a period of time.
    Type: Grant
    Filed: October 13, 2014
    Date of Patent: December 31, 2019
    Inventors: Sarnath Chattaraj, Kiem H. Dang, Hsi Chung Fusselman, Poonam S. Gulati, Lance P. Hoffman, Guangping Zhang
  • Patent number: 10514336
    Abstract: The invention relates to a terahertz measuring device (1) for measuring a test object (7), comprising: a THz transmitter and receiver unit (2) for emitting terahertz radiation (3) at a spatial angle of emittance (4) along an optical axis (A), receiving reflected terahertz radiation (8) and generating a signal amplitude (S) as a function of the time or frequency (t, f), and a controller and evaluator device (12) for receiving and evaluating the signal amplitude (S). Hereby, the controller and evaluator device (12) determines defects (10, 110) of the test object (7) from the signal amplitude (S). In particular, it is possible to mask a core area (4a) of the emitted terahertz radiation (3). An alternative measuring arrangement can reveal defects also by injecting the THz radiation at a right angle in that additional measuring peaks are detected which cannot be associated with the layer thickness measurement as such.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: December 24, 2019
    Assignee: INOEX GmbH Innovationen und Ausruestungen fuer die Extrusionstechnik
    Inventor: Marius Thiel
  • Patent number: 10499679
    Abstract: Disclosed is a food wash sensor system that includes a sensor disposed along a fluid flow path that can circulate a wash fluid through the food wash sensor system. The sensor can detect a concentration of an analyte in the wash fluid. The system also includes a reference fluid reservoir including a reference fluid, the reference fluid including a predetermined concentration of the analyte in solution, a delivery system fluidly coupled to the fluid flow path and operable to supply the reference fluid to the fluid flow path upstream from the sensor while maintaining the sensor in place along the fluid flow path, and a control and monitoring system configured to receive a signal from the sensor, the signal indicating the concentration of the analyte in the reference fluid at a first time, and control calibrating the sensor and validating the sensor over time based on the received signal.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: December 10, 2019
    Inventors: James M. Brennan, Danny Elmer Lindstrom, Christopher Michael McGinnis, Eric Child Wilhelmsen
  • Patent number: 10463303
    Abstract: An apparatus for use in securing a reusable medical device to an exterior surface of a patient's body includes a cushion, a first adhesive member, and a second adhesive member. The cushion includes a bottom side, a top side opposite the bottom side, and an opening adapted to receive at least a portion of the reusable medical device therein. The first adhesive member includes an upper adhesive surface and lower adhesive surface opposite the upper adhesive surface. The second adhesive member is interposed between the cushion and the first adhesive member, and includes a first adhesive surface and a second adhesive surface opposite the first adhesive surface.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: November 5, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Nicholas M. Donnay, Lawrence D. Swanson, Adam Fischbach
  • Patent number: 10448876
    Abstract: Systems and methods for analyzing sublingual microcirculation perfusion and identifying particular nerve tracts. In exemplary embodiments, a digital micro-mirror device is configured to direct a reflected light to a subject area and a controller is configured to alter a parameter of the reflected light.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: October 22, 2019
    Assignee: KCI Licensing, Inc.
    Inventor: George Hutchinson
  • Patent number: 10448895
    Abstract: A sensor sheath for a catheter. The sensor sheath includes a substrate having at least one sensor associated therewith; and an electronics unit in communication with at the at least one sensor, wherein the substrate is configured to attach to a catheter.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 22, 2019
    Inventors: Prashant Tathireddy, Carlos Mastrangelo, Florian Solzbacher, Nassir Marrouche, Jules Magda
  • Patent number: 10451629
    Abstract: A component measuring device includes a calibration member that is slidably disposed in an insertion hole of a chip attachment unit and a biasing member that biases the calibration member toward an insertion port. The calibration member is held by the biasing member at a position where the calibration member blocks the introduction port and a lead-out port and where light from a light emitter is applied to the calibration member when a measuring chip is not inserted in the insertion hole, and slides to a side opposite to the insertion port along with insertion of the measuring chip into the insertion hole so that light from the light emitter is applied to the measuring chip.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: October 22, 2019
    Inventor: Masao Takinami
  • Patent number: 10433789
    Abstract: A device and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin. Such a device allows a sensor to penetrate mammalian skin without the use of an introducer device such as a needle. A device in accordance with embodiments of the present disclosure includes a housing for attachment to mammalian skin including an exit port for receiving the distal end of a biosensor and an injection activation device including a mechanism for forcing the sensing device from a first position within the housing, through the exit port to a second position, with sufficiently high velocity to partially penetrate the mammalian skin.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 8, 2019
    Inventors: Mark Neinast, Robert Bruce, W. Kenneth Ward, Richard G. Sass, Jon Fortuna
  • Patent number: 10432717
    Abstract: Embodiments of the present application enable setup synchronization of an end user medical device (110) such as a blood glucose meter. The invention includes a controller (302) including a memory (304); a transceiver (306) operatively coupled to the controller; and a host computer (104) interface (208) operative to couple the controller to a host computer, wherein the memory is operative to store instructions executable on the controller. The instructions are adapted to cause the controller to scan for an advertising medical device using the transceiver, establish a communications connection with a medical device advertising for synchronization, and transmit synchronization data to a medical device once a communication connection has been established. Numerous other aspects are disclosed.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: October 1, 2019
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Igor Gofman, Christopher Dionisio
  • Patent number: 10410538
    Abstract: Provided are systems and methods using which users may learn and become familiar with the effects of various aspects of their lifestyle on their health, e.g., users may learn about how food and/or exercise affects their glucose level and other physiological parameters, as well as overall health. In some cases the user selects a program to try; in other cases, a computing environment embodying the system suggests programs to try, including on the basis of pattern recognition, i.e., by the computing environment determining how a user could improve a detected pattern in some way. In this way, users such as type II diabetics or even users who are only prediabetic or non-diabetic may learn healthy habits to benefit their health.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: September 10, 2019
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, Robert J. Boock, David DeRenzy, Laura J. Dunn, Matthew Lawrence Johnson, Katherine Yerre Koehler, Apurv Ullas Kamath, Andrew Attila Pal, David Price, Eli Reihman, Mark Wu
  • Patent number: 10405885
    Abstract: A medical applicator and a manipulation unit for use in connection with specific variants of the medical applicator are disclosed. In general, the medical applicator has an insertion needle (108; 308) configured for puncturing a part of a human or animal body (B), a sensor assembly (110; 310) configured to be at least partially inserted into a human or animal body (B) when the body is punctured by said insertion needle (108; 308) and a lifting means (102; 301, 302) for lifting up a surface adjacent portion of the human or animal body (B) towards the insertion needle (108; 308).
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: September 10, 2019
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Oliver Kube, Michael Orth, Helmut Walter
  • Patent number: 10398529
    Abstract: A wearable body composition analyzer according to various embodiments of the present disclosure may include an induction part for inducing secretion of bodily liquid while being in contact with a body part, a collection part that collects the bodily liquid secreted, a sensor part that detects a body composition from the bodily liquid collected, and a wearable part to which the induction part and the collection part is detachably attached, wherein the wearable part may be worn on a body. The above-described wearable body composition analyzer may be implemented variously according to embodiments.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: September 3, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Chul-Ho Cho, Kwang-Bok Kim, Seong-Je Cho, Young-Kyu Cho, Seung-Min Lee, Jeong-Gun Lee, Sun-Tae Jung, Jae-Geol Cho
  • Patent number: 10390758
    Abstract: Provided is an electronic device to monitor a user's biological measurements in two stages, where the first stage determines whether to make measurements and/or appraisals in the second stage.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: August 27, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Matthew C. Wiggins, Euan S. Thomson
  • Patent number: 10383557
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: August 20, 2019
    Assignee: Profusa, Inc.
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William A. McMillan
  • Patent number: 10383556
    Abstract: A medical diagnostic device includes a wirelessly transmitted time data receiver and processor. Associated devices, methods and functionality are also described.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: August 20, 2019
    Assignee: Intuity Medical, Inc.
    Inventors: Kelley J. Lipman, Michael F. Tomasco, Daniel N. Brncic, David K. Hohl, Paul D. Reynolds, Raul Escutia
  • Patent number: 10376665
    Abstract: A fluid dispensing catheter including an elongate body having a proximal portion and a distal portion and defining a passage between the proximal and distal portions, and a plug having a proximal section positioned within the passage in the distal portion of the elongate body to partially occlude the passage, the plug being substantially cylindrical and having a flat parallel to and offset from a longitudinal axis of the plug, the flat defining a gap with the elongate body.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: August 13, 2019
    Assignee: COVIDIEN LP
    Inventors: Katherine A. Herdina, Thomas D. Magnuson
  • Patent number: 10376213
    Abstract: Embodiments provide a sensor insertion tool (SIT) that provides a motive force for insertion of an analyte sensor into/through skin. A SIT may be releasably locked to one or more components of a sensor insertion system, such that components of the sensor insertion system remain securely coupled during sensor insertion. A SIT may include a release member that unlocks or uncouples the SIT and the other components after sensor insertion. In various embodiments, a SIT may be a component of a sensor insertion system configured for assembly by an end user, a health care professional, and/or a caretaker prior to sensor insertion, and may act in cooperation with other sensor insertion system components. Additional components and methods of assembly and use are also provided herein.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: August 13, 2019
    Inventors: Robert Bruce, David Kreitlow, Isaac Federiuk, Ryan Polcin, Dennis Slomski, Eric Ward, Mihai Resch
  • Patent number: 10360419
    Abstract: A wearable device includes a radio-frequency identification (RFID) tag having a memory that stores identification information. The wearable device also has a power harvesting circuit configured to harness power from electromagnetic radiation. Further, the wearable device has a sensor coupled to the power harvesting circuit and configured to utilize the power to monitor a condition of the wearable device. Even further, the wearable device has a microcontroller coupled to the sensor and configured to write data indicative of the condition to the memory of the RFID tag, wherein the RFID tag is configured to transmit the identification information and the data in response to receipt of the electromagnetic radiation from an RFID reader.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: July 23, 2019
    Assignee: Universal City Studios LLC
    Inventors: Wei Cheng Yeh, Travis Jon Cossairt
  • Patent number: 10349871
    Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: July 16, 2019
    Assignee: DexCom, Inc.
    Inventors: Phil Mayou, Hari Hampapuram, David Price, Keri Weindel, Kostyantyn Snisarenko, Michael Robert Mensinger, Leif N. Bowman, Robert J. Boock, Apurv Ullas Kamath, Eli Reihman, Peter C. Simpson
  • Patent number: 10342444
    Abstract: Disclosed systems include mobile ECG sensors, systems and methods. Some embodiments provide ECG sensors in a credit card form factor that allows a user to contact two electrically isolated electrodes to measure heart electrical signals for a Lead I ECG.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: July 9, 2019
    Assignee: AliveCor, Inc.
    Inventors: David E. Albert, Simon Prakash, Bruce Satchwell, Jonathan Beck
  • Patent number: 10342489
    Abstract: Method and apparatus for inserting at least a portion of a sensor into a patient is provided.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: July 9, 2019
    Inventor: Gary Ashley Stafford
  • Patent number: 10335032
    Abstract: Systems and methods for monitoring of biometric and contextual variables to assist in screening for, quantification of, and prediction of smoking behavior, and for assisting in smoking cessation are described.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: July 2, 2019
    Assignee: Carrot, Inc.
    Inventors: David S. Utley, Allen Jameson, Jennifer Marler
  • Patent number: 10327638
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: June 25, 2019
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Paul V. Neale, Peter C. Simpson, James H. Brauker, James Patrick Thrower, Mark Shults, Rathbun K. Rhodes, Paul V. Goode, Jr., Arnold L. Holmquist
  • Patent number: 10321858
    Abstract: Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: June 18, 2019
    Assignee: ProteaDX, Inc.
    Inventors: Jose Antonio Maiz-Aguinaga, Lennart Olsson
  • Patent number: 10299216
    Abstract: Vehicle management systems can be configured to help govern self-driving vehicles. A vehicle management system can communicatively couple a self-driving vehicle to a remote computing device of a user of the vehicle. Detecting a battery charge indication below a threshold can trigger several responses configured to minimize the risk of the self-driving vehicle failing to pick up the user due to the remote computing device having a low or dead battery.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: May 21, 2019
    Inventors: Eric John Wengreen, Wesley Edward Schwie
  • Patent number: 10286198
    Abstract: Devices and methods are provided for controlled delivery of medical substances such as drugs and medication. For example, a microchip medical substance delivery device includes a control system, and a medical substance capsule that comprises a medical substance contained with a reservoir, and a release structure to release the medical substance from within the reservoir in response to an activation signal generated by the control system. The control system comprises a wireless signal receiving element, processor, actuator circuit, and power supply source. The wireless signal receiving element captures a wireless signal. The processor detects an activation code embedded within the captured wireless signal, and generates an actuator control signal in response to the detection of the activation code. The actuator circuit generates the activation signal in response to the actuator control signal generated by the processor. The power supply source provides power to operate components of the control system.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: May 14, 2019
    Assignee: International Business Machines Corporation
    Inventors: Bing Dang, Duixian Liu, Jean-Olivier Plouchart
  • Patent number: 10285759
    Abstract: The invention provides systems and method for the removal of diseased cells during surgery.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 14, 2019
    Assignee: Lumicell, Inc.
    Inventors: W. David Lee, Jorge Ferrer
  • Patent number: 10252052
    Abstract: The invention contemplates, inter alia, the use of remote ischemic conditioning in the treatment of a variety of disorders.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 9, 2019
    Assignee: The Hospital for Sick Children
    Inventor: Andrew Redington
  • Patent number: 10245422
    Abstract: Applicators for a microprojection array and methods of using the applicators are described.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 2, 2019
    Assignee: Corium International, Inc.
    Inventors: Anthony Le, Doug Bourne, Ashutosh Shastry, Robert Wade Worsham, Parminder Singh
  • Patent number: 10238325
    Abstract: A biological fluid sampling device for collecting a blood sample from a separate vascular access device and for ejecting a portion of the collected sample to a point-of-care testing device for analysis is provided. The biological fluid sampling device includes a body enclosing a reservoir. The reservoir has an internal volume sufficient to contain enough blood for use in a diagnostic test. The sampling device further includes: an access lumen extending from a distal end of the body for establishing fluid communication between a separate vascular access device and the reservoir; an outflow lumen also in fluid communication with the reservoir; and a removable vented cap attached to the outflow lumen including a gas permeable vent in gaseous communication between the reservoir and ambient air. In addition, several sample and transfer devices are provided for obtaining a sample from a subject and transferring the sample to a point-of-care testing device.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: March 26, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Jonathan Karl Burkholz, Bryan Garret Davis
  • Patent number: 10231654
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: March 19, 2019
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Thomas A. Peyser, Adam Heller
  • Patent number: 10219710
    Abstract: A device for adjusting and determining the blood flow plateau at a patient's limb, wherein the device includes an chamber the wall of which surrounds an inner space, and at least one opening for inserting at least a part of the limb into the inner space as well as at least one recess, that allows access to the part of the limb that is located inside the inner space, are formed in the chamber, and wherein the device includes at least one heating element that is in thermal contact with the inner space. In this context, it is provided that the device further includes an apparatus for determining the blood flow plateau at the part of the limb that is located inside the inner space.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: March 5, 2019
    Inventors: Graeme Eisenhofer, Christina Pamporaki, Angelos Filippatos
  • Patent number: 10211679
    Abstract: A system using a hybrid source of energy supply scheme is disclosed. The system includes a first circuit configured to transmit and receive electromagnetic waves, where the first circuit is configured to operate in one of a plurality of operation modes, where the plurality of operation modes includes a normal operation mode, an energy harvesting mode, and a sleep mode. The system further includes a second circuit coupled to the first circuit and configured in one of the plurality of operation modes. The second circuit includes at least one of a receiver or a transmitter, and a third circuit coupled to the first circuit and the second circuit. The third circuit configured to the normal operation mode when the first circuit is configured in the normal operation mode and the second circuit is configured in a normal operation mode.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: February 19, 2019
    Inventors: Qiang Li, Ming Yu Lin
  • Patent number: 10206572
    Abstract: Systems and methods for monitoring of biometric and contextual variables to assist in screening for, quantification of, and prediction of smoking behavior, and for assisting in smoking cessation are described.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: February 19, 2019
    Assignee: Carrot, Inc.
    Inventors: David S. Utley, Allen Jameson, Jennifer Marler
  • Patent number: 10194868
    Abstract: Methods and apparatuses for determining an analyte value are disclosed.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: February 5, 2019
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Erwin Satrya Budiman
  • Patent number: 10198555
    Abstract: A method and apparatus implements patient data downloading for multiple different meter types, such as multiple different blood glucose meters. A plurality of serial ports is provided, each arranged for connection to a respective meter of the multiple different meter types. Information is displayed and user selections are identified. Responsive to user entry identifying a particular meter type, a connection port/cable number for the meter connection is displayed for viewing by the user. Predefined instructions for the particular meter type are displayed. A data collection computer system is provided as an integral unit including a unitary housing containing a processor device, a printer, and a display touch screen. When a meter connection is identified, information is displayed, patient data is downloaded from the meter and is printed in a selected format together with selected reports generated from the downloaded patient data.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: February 5, 2019
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Brian C. Thompson, Joseph E. Ruggiero, Richard A. Lett
  • Patent number: 10195404
    Abstract: A chest drainage system, including a circulation assembly having an intake for taking fluid into the system and an exhaust for exhausting fluid out of the system. An intake flow device is configured to selectively control fluid flow through the intake and an exhaust flow device is configured to selectively controlling fluid flow through the exhaust. The circulation assembly has a first configuration and a second configuration such that transitioning between the first and second configurations during operation of the circulation assembly displaces at least a portion of fluid within the system with fluid from outside the system via the intake and the exhaust. A sensor is arranged in fluid communication with the fluid within the system and configured to detect a concentration of a reference fluid in the fluid in the system.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: February 5, 2019
    Inventors: Wolfram Grziwa, Greg Peatfield