Measuring Or Detecting Nonradioactive Constituent Of Body Liquid By Means Placed Against Or In Body Throughout Test Patents (Class 600/309)
  • Patent number: 11064917
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: July 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Apurv Ullas Kamath, Aarthi Mahalingam, Jack Pryor, Matthew D. Wightlin
  • Patent number: 11062798
    Abstract: A method includes obtaining blood glucose measurements and blood glucose times of a patient from a blood glucose meter and executing a patient management program configured to display on a screen a graphical user interface having a trend window of the blood glucose measurements on the time line. The patient management program is configured to receive, in the trend window magnifying inputs for a magnification window superimposed on a segment of the timeline to specify a date range for a magnified window. The patient management program is further configured to display the magnified window including the blood glucose measurements of the patient from the specified date range and display a first information window including quantitative information associated with the blood glucose measurements from the specified date range.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: July 13, 2021
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Robert Salitsky, Andrew Rhinehart
  • Patent number: 11045128
    Abstract: A multi-lumen catheter for monitoring intra-abdominal pressure, the catheter including an expandable outer balloon and an expandable inner balloon positioned within the outer balloon. A first lumen communicates with the inner balloon and the inner balloon and first lumen are filled with gas to form a gas filled chamber to monitor pressure within the bladder to thereby monitor pressure within an abdomen of the patient. A second lumen communicates with the bladder to remove fluid from the bladder. The catheter is configured for attachment of an external pressure transducer communicating with the gas filled chamber for measuring bladder pressure based on gas compression caused by deformation of the expanded inner balloon deformed by the expanded outer balloon.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: June 29, 2021
    Assignee: Sentinel Medical Technologies, LLC
    Inventors: Timothy McKinney, Marc-Alan Levine
  • Patent number: 11045120
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: June 29, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Victor Ha, Apurv Ullas Kamath, Aarthi Mahalingam, Steve Masterson, Melissa A. Nicholas, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Vance Swanson, Matthew D. Wightlin, Kum Ming Woo
  • Patent number: 11026605
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: June 8, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Victor Ha, Apurv Ullas Kamath, Aarthi Mahalingam, Steve Masterson, Melissa A. Nicholas, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Vance Swanson, Matthew D. Wightlin, Kum Ming Woo
  • Patent number: 11026629
    Abstract: A biological information detection device includes: a needle body configured to pierce the living body; and a sensor that has an elongated shape and is configured to detect biological information using a distal end portion of the sensor that is configured to indwell inside a living body. The distal end portion of the sensor is insertable into the living body by moving along the needle body after the needle body has pierced the living body.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: June 8, 2021
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Hideyuki Momoki, Yasuhiro Kobayashi
  • Patent number: 11020019
    Abstract: An analyte monitoring system and methods for extending the life of a sensor in an analyte monitoring system. The analyte sensor may include an analyte sensor and a transceiver. The analyte sensor may include an indicator, a detector, and an amplifier. The indicator may be configured to exhibit one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The detector may be configured to detect one or more of the detectable properties and output an analyte signal indicative of the amount or concentration of the analyte in proximity to the indicator. The amplifier may be configured to amplify the analyte signal. The transceiver may be configured to adjust a gain of the amplifier. The transceiver may be configured to additionally or alternatively adjust a drive current of a light source of the analyte sensor.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: June 1, 2021
    Assignee: Senseonics, Incorporated
    Inventors: Andrew DeHennis, Abhi Chavan, Eitan Saba-Keren
  • Patent number: 11020028
    Abstract: The invention disclosed herein includes sensors having three dimensional configurations that allow expansive “360°” sensing (i.e. sensing analyte from multiple directions) in the environments in which such sensors are disposed. Embodiments of the invention provide analyte sensors having foldable substrates adapted to produce optimized configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: June 1, 2021
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Megan E. Little, Katherine T. Wolfe, Raghavendhar Gautham, Bradley C. Liang, Rajiv Shah
  • Patent number: 11000671
    Abstract: A catheter has extruded length of tubing and an injection molded tip that facilitates insertion of the catheter into the body. The catheter is fabricated by the steps of providing the tubing, for example, by extruding the tubing from a thermoplastic resin cutting the tubing to the desired length, inserting a plug into the tubing, inserting one end of the tubing into an injection mold cavity, creating and forming a tip in an injection molding step, and demolding the tubing with the formed tip.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: May 11, 2021
    Assignee: Hollister Incorporated
    Inventor: Thomas H. Gilman
  • Patent number: 11000213
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: May 11, 2021
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Jack Pryor, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10993642
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: May 4, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Apurv Ullas Kamath, Aarthi Mahalingam, Jack Pryor, Matthew D. Wightlin
  • Patent number: 10980448
    Abstract: A sensor device, such as a biosensor, may comprise a polymer substrate, which is structured so as to form sets of microneedles and respective vias. The microneedles extend, each, from a base surface of the substrate. Each of the vias extends through a thickness of the substrate, thereby forming a corresponding set of apertures on the base surface. Each of the apertures is adjacent to a respective one of the microneedles. The device further may comprise two or more electrodes, these including a sensing electrode and a reference electrode. Each electrode may comprise an electrically conductive material layer that coats a region of the substrate, so as to coat at least some of the microneedles and neighboring portions of said base surface. Related devices, apparatuses, and methods of fabrication and use of such devices may be provided.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: April 20, 2021
    Assignee: International Business Machines Corporation
    Inventors: Neil Ebejer, Ute Drechsler, Patrick Ruch
  • Patent number: 10980452
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: April 20, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Apurv Ullas Kamath, Steve Masterson, Aarthi Mahalingam, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10979922
    Abstract: An estimation device includes a processor configured to: detect an error of data obtained by receiving a wireless signal from a medical device; correct the detected error; determine whether or not there is a noise due to an external generation source at a time of acquiring the wireless signal from the medical device, based on detection information relevant to the detected error or correction information relevant to the corrected error; and estimate a cause of the noise, based on the detection information or the correction information. The detection information is at least one of the number of detections of the error, continuousness of the error, and periodicity of the error, and the correction information is at least one of the number of corrections of the error, continuousness of data in which the error is corrected, and periodicity of data in which the error is corrected.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: April 13, 2021
    Assignee: OLYMPUS CORPORATION
    Inventors: Tetsuo Minai, Takeshi Nishiyama
  • Patent number: 10953245
    Abstract: An apparatus for treating tissue includes a first energy application device to direct energy at tissue of a patient to cause at least one channel to be formed and a controller to control application of energy from the first energy application device to form the at least one channel. The at least one channel may be in the shape of a spiral-like shape or may be in a flower-like shape. Mechanisms are provided to help open channels formed in the human skin structure. A second energy application source may be used to maintain the channel open after formation. The controller may cause the first energy application device to form a plurality of channels of varying depth, width and distribution over the human skin surface. The apparatus to control the application of energy may be operated using a foot-activated pedal.
    Type: Grant
    Filed: November 4, 2017
    Date of Patent: March 23, 2021
    Assignee: LUMENIS LTD.
    Inventors: Idan Aviad, Yoni Iger, Assaf Gelstein, A. Jason Mirabito, Omer Peled
  • Patent number: 10932700
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: March 2, 2021
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, James H. Brauker, Mark C. Brister, Paul V. Goode, Jr., Apurv Ullas Kamath, Aarthi Mahalingam, Jack Pryor, Matthew D. Wightlin
  • Patent number: 10925524
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: February 23, 2021
    Assignee: DexCom, Inc.
    Inventors: Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10918318
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10918313
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10918315
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10918314
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10918317
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10918316
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: February 16, 2021
    Assignee: DexCom, Inc.
    Inventors: Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10908114
    Abstract: Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: February 2, 2021
    Assignee: DexCom, Inc.
    Inventors: Michael J. Estes, Jennifer Blackwell, Sebastian Bohm, Robert J. Boock, Jack Pryor, Peter C. Simpson, Matthew D. Wightlin
  • Patent number: 10898114
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: January 26, 2021
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Paul V. Goode, Jr., Aarthi Mahalingam, Jack Pryor
  • Patent number: 10898116
    Abstract: Methods and systems for manufacturing a transdermal sampling and analysis device for non-invasively and transdermally obtaining biological samples from a subject and determining levels of analytes of the obtained biological samples are provided. A method of manufacturing the device may improve performance and includes forming channel structures on the lid of the device, thereby making the spacer/channel support structures physically independent and separable from the sensing electrode. Other methods of manufacturing the device may improve performance and include forming at least one of the electrodes on each of the base and the lid, and forming a recessed second spacer layer over the channel support structures, thereby separating the channel support structures and the electrode on the lid to allow a larger area of the electrode to be exposed to the biological sample.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 26, 2021
    Assignee: Cambridge Medical Technologies LLC
    Inventors: Joseph J Vidalis, Joseph A Marcanio, John Frederick Currie, Helena Woodvine Snyder, Vikas Bhatia
  • Patent number: 10888396
    Abstract: Detection of placement of dental aligners in patient mouth on teeth for indication of wearing compliance. Described herein are apparatuses and methods for detecting wearing, including compliance. In some variations these apparatuses and methods may include a sensor configured to detect deflection of the one or more deflectable structures. In some variations, these apparatuses and methods may include a proximity sensor coupled to the appliance shell and configured to generate sensor data when in proximity with intraoral tissue.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: January 12, 2021
    Assignee: Align Technology, Inc.
    Inventors: Yaser Shanjani, Bruce Cam, Jun Sato, John Y. Morton, Victor Chen, Chunhua Li, Allen R. Boronkay, Srinivas Kaza
  • Patent number: 10874335
    Abstract: Disclosed is a wearable electronic device including a body portion wearable on a human body, a circuit portion mounted on the body portion, and a sensor portion contacting the human body to measure a bio signal, wherein the sensor portion is detachably coupled to the body portion.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: December 29, 2020
    Inventors: Chul-Ho Cho, Seong-Wook Jo, Seung-Min Lee, Jea-Hyuck Lee, Seong-Je Cho, Jae-Geol Cho, Sun-Tae Jung
  • Patent number: 10874337
    Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: December 29, 2020
    Assignee: Profusa, Inc.
    Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William A. McMillan
  • Patent number: 10857394
    Abstract: Disclosed herein is a novel reconfigurable spatial and temporal light modulation method that exploits the imaging medium itself by employing a multi-element ultrasonic transducer array as an in-situ acoustic modulator. The medium density can be modulated using different ultrasonic pressure patterns to pattern an incident collimated beam of light.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: December 8, 2020
    Assignee: CARNEGIE MELLON UNIVERSITY
    Inventors: Maysamreza Chamanzar, Yasin Karimi, Matteo Giuseppe Scopelliti
  • Patent number: 10856787
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 8, 2020
    Assignee: DexCom, Inc.
    Inventors: Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker, Aarthi Mahalingam
  • Patent number: 10857308
    Abstract: A needle housing having a distal end which is removably connectable to a source of injectable fluid and a proximal end for contacting a patient. The needle housing comprises (a) a hollow needle having a proximal end for insertion into body tissue of the patient, and (b) a chamber having an open proximal end, the chamber surrounding at least part of the needle and extending proximally beyond the proximal end of the needle to the open proximal end. The open proximal end of the chamber is deformable and moveable relative to the needle from a position in which the chamber extends proximally beyond the proximal end of the needle to a position in which the proximal end of the needle extends proximally through the open proximal end of the chamber.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: December 8, 2020
    Inventor: Massoud Hosseini Ardehali
  • Patent number: 10859527
    Abstract: The disclosure relates to electrodes and related sensor apparatus for the detection of nitric oxide (NO) and/or peroxynitrite (PON). The electrodes and sensors incorporate electrically conducting boron-doped diamond (BDD) to provide a selective and quantitative detection platform. The sensing electrode for detection of NO includes metallic nanoparticles for oxidation of NO as well as anionic polyelectrolyte layer over the electrically conducting BDD layer. The sensing electrode for detection of PON includes an electrically conductive polymeric layer including a metal-complexed porphyrin for redox reaction with PON over the electrically conducting BDD layer. A corresponding sensor apparatus includes one or two electrochemical cells with associated electrolytes, separate working electrodes for the separate, selective detection of NO or PON, and associated reference electrode(s) and counter electrode(s).
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: December 8, 2020
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Greg M. Swain, Serban F. Peteu, Borys W. Hrinczenko
  • Patent number: 10849510
    Abstract: Methods of monitoring arterial blood using an arterial line tube positions adjacent to a groin sheath, as part of a surgical intervention. Described herein are methods and apparatuses (e.g., systems) for introduction of an arterial line tube for contemporaneous and sensitive blood pressure monitoring along with other instrumentation in the course of a therapeutic intervention through a femoral artery, affording improved monitoring results.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: December 1, 2020
    Assignee: Razack Intellectual Properties, LLC
    Inventor: Nasser Razack
  • Patent number: 10827954
    Abstract: Low profile continuous analyte measurement systems and systems and methods for implantation within the skin of a patient are provided.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: November 10, 2020
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Udo Hoss, John Charles Mazza, Phu Le
  • Patent number: 10828418
    Abstract: An infusion set configured to be secured to a skin surface for targeting a desired depth to deliver content to an upper skin surface, comprising a hub and a needle configured to travel during insertion as urged by a motion, wherein said needle is configured to assume a first angle relative to said skin surface in a free state, and wherein said needle is configured to return toward said first angle relative to said skin surface upon release of said motion, wherein said motion is at an angle relative to said skin surface that is different from said first angle of said needle.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: November 10, 2020
    Assignee: Becton, Dickinson and Company
    Inventors: Cole Constantineau, Ryan Schoonmaker, Michel Bruehwiler, Eric Bené
  • Patent number: 10813577
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: October 27, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, James R. Petisce, Kum Ming Woo, Victor Ha, Melissa A. Nicholas, Peter C. Simpson, Matthew D. Wightlin, Steve Masterson, John Nolting, Jack Pryor, Sean Saint, Vance Swanson
  • Patent number: 10799159
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: October 13, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10799158
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: October 13, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10788416
    Abstract: A colorimetric wet chemistry analyzer for determining a concentration of an analyte of interest in a sample is provided. The analyzer comprising includes a reaction chamber configured to receive the sample and facilitate a reaction that changes a color of the sample based on the concentration of the analyte of interest. A photometric cell is operably coupled to the reaction chamber to receive the sample and direct illumination therethrough. The photometric cell has a first illumination source configured to provide illumination at a first wavelength through the photometric cell and a second illumination source configured to provide illumination at a second wavelength through the photometric cell. The second wavelength is different than the first wavelength. A photo detector is configured to detect illumination passing through the photometric cell.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: September 29, 2020
    Assignee: Rosemount Inc.
    Inventors: Bradley A. Butcher, Chang-Dong Feng
  • Patent number: 10758700
    Abstract: A closed-circuit heliox delivery system and methods for alleviating symptoms of COPD and related disorders are provided. The system is self-monitoring and can be used outside of a hospital environment. The system contains a gas supply fluidly connected to a breathing circuit. The breathing circuit contains an upper airway device, such as a mask. The system contains a sensor(s) and controller. The sensors measure parameters in the system, the ambient environment, or related to the physiological state of the user. The controller can adjust the system to maintain parameters within the device, i.e. pressure, temperature, humidity, within predetermined ranges. The controller can adjust the system to maintain a target physiological state of the user, i.e. target blood oxygen levels or Work of Breathing (WOB).
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: September 1, 2020
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Sairam Parthasarathy, Marvin J. Slepian
  • Patent number: 10761348
    Abstract: A lens comprises an internal cavity structure formed by dissolution of a soluble insert material. The internal soluble material may dissolve through a body of a lens such as a contact lens in order to form the cavity within the contact lens. The cavity within the lens can be shaped in many ways, and corresponds to the shape of the dissolved material, such that many internal cavity shapes can be readily fabricated within the contact lens. The insert can be placed in a mold with a pre-polymer material, and the pre-polymer material cured with the insert placed in the mold to form the lens body. The polymerized polymer may comprise a low expansion polymer in order to inhibit expansion of the lens when hydrated. The polymer may comprise a hydrogel when hydrated. The soft contact lens material comprises a sufficient amount of cross-linking to provide structure to the lens and shape the cavity.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: September 1, 2020
    Assignee: OneFocus Vision, Inc.
    Inventors: Adam Harant, Amelia Davenport, Neil Cramer, Steve Waite, Amitava Gupta, William J. Link, Gamil Alhakimi, Lisa Studnicki, Musa Alhakimi
  • Patent number: 10750981
    Abstract: A remote device includes a biosensor interface that is configured to collect biosensor data from an integrated biosensor or by receiving biosensor data from one or more external biosensors or other types of sensors either through a wireless connection or a wired connection. The remote device communicates with a television to display the biosensor data on the television. The television may communicate biosensor data to third party, such as a pharmacy or physician's office or service provider.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: August 25, 2020
    Assignee: SANMINA CORPORATION
    Inventor: Robert Steven Newberry
  • Patent number: 10743801
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: August 18, 2020
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Paul V. Goode, Jr., Aarthi Mahalingam, Jack Pryor
  • Patent number: 10729383
    Abstract: A disease prediction model construction apparatus is provided. The disease prediction model construction apparatus may include a spectral data acquisition unit that emits near-infrared rays toward a skin of a subject to acquire near-infrared spectral data and a prediction model construction unit that constructs a disease prediction model based on a time-blood glucose graph generated from the acquired near-infrared spectral data.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: August 4, 2020
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Eui Seok Shin, Jin Young Park, Seung Jun Lee
  • Patent number: 10722152
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: July 28, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Steve Masterson, John Nolting, James R. Petisce, Jack Pryor, Sean Saint, Peter C. Simpson, Vance Swanson, Matthew D. Wightlin
  • Patent number: 10722690
    Abstract: Pressure sensing guidewires are disclosed. The pressure sensing guidewires may include a tubular member having a proximal portion and a distal portion. The distal portion may have a plurality of slots formed therein. The distal portion may have a first wall thickness along a first region and a second wall thickness smaller than the first wall thickness along a second region. A pressure sensor may be disposed within the distal portion of the tubular member and housed within the second region. An anti-thrombogenic coating may be disposed on an inner surface, an outer surface, or both of the second region of the distal portion of the tubular member.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: July 28, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Roger W. McGowan, Brice Lee Shireman
  • Patent number: 10718693
    Abstract: Disclosed embodiments concern histochemical process compositions comprising at least one nanoparticle in an amount effective to reduce or substantially eliminate the average number of spots per slide that result from a sample staining protocol. The nanoparticle can be any of various nanoparticles, or combinations thereof, including metals, metal alloys, metal oxides, ceramics, functionalized metals or metalloids, and other miscellaneous nanoparticles, such as carbon nanoparticles and diamond nanoparticles. Typically, the nanoparticle concentration is from greater than zero to at least about 25 parts per million, more typically from about 2 parts per million to about 20 parts per million. Embodiments of a method for using process nanosolutions also are disclosed. One embodiment concerns applying a histochemical process composition to a sample, followed by performing a staining protocol on the sample.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: July 21, 2020
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Merrill Jackson, Michael Herman, Grace Hoben, Noemi Sebastiao, Scott Cockayne, Heather Ferrea
  • Patent number: 10716498
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: July 21, 2020
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Paul V. Goode, Jr., Aarthi Mahalingam, Jack Pryor
  • Patent number: 10709364
    Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: July 14, 2020
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Paul V. Goode, Jr., Aarthi Mahalingam, Jack Pryor