Electrode In Artery Or Blood Vessel Patents (Class 600/381)
  • Patent number: 11096617
    Abstract: The present disclosure provides systems and methods for detecting cardiac activation times of a patient. A system includes a data acquisition system and a processor communicatively coupled thereto. The data acquisition system is configured to detect a plurality of electrograms generated at a plurality of respective electrodes coupled to the patient. The processor is configured to receive the plurality of electrograms from the data acquisition system. The processor is further configured to compute respective energies of the plurality of electrograms. The processor is further configured to detect a cardiac activation time for a first electrogram among the plurality of electrograms based on the respective energy of the first electrogram and the respective energy of a second electrogram that neighbors the first electrogram.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: August 24, 2021
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: Dongfeng Han, Valtino X. Afonso
  • Patent number: 11083513
    Abstract: A catheter device for ablating biological material is described. The catheter device comprises (a) a longitudinal structure; (b) an applicator for ablating the biological material, wherein the applicator is installed at the longitudinal structure; (c) a first electrode being attached to the longitudinal structure; (d) a second electrode being attached to the longitudinal structure; (e) an interface being connected directly or indirectly to the longitudinal structure; (f) a first lead electrically connecting the first electrode with the interface; and (g) a second lead electrically connecting the second electrode with the interface. The interface is configured for electrically connecting the first lead and the second lead with a measurement device for electrically stimulating the first electrode and the second electrode and for detecting an electric quantity being associated with an electric response of an biological material being located in between the two stimulated electrodes.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: August 10, 2021
    Assignee: Afreeze GmbH
    Inventor: Gerald Fischer
  • Patent number: 10994131
    Abstract: Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: May 4, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Dominique M. Durand, Brian Wodlinger
  • Patent number: 10926085
    Abstract: A system and method for positioning sheaths into the Coronary Sinus using a guiderail catheter.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: February 23, 2021
    Assignee: MWest, LLC
    Inventor: Michael B. West
  • Patent number: 10751469
    Abstract: A drug delivery and monitoring device comprising a nerve stimulating element configured to deliver an electric stimulus, a recording element configured to detect a compound action potential, and a drug-delivery element.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: August 25, 2020
    Assignee: Northwesten University
    Inventors: Matthieu Kevin Chardon, Michael David Johnson, Charles Heckman, II, Santhanam Suresh
  • Patent number: 10751107
    Abstract: A vapor delivery needle is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, or denature tissues of the prostate. Methods associated with use of the energy delivery probe are also covered.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: August 25, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Michael Hoey, Roger Noel Hastings, Mark Schrom, Matthew Byrne, Grant Mauch, Eric Jerke, Richard Charles Kravik
  • Patent number: 10702330
    Abstract: A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: July 7, 2020
    Assignee: AtriCure, Inc.
    Inventors: James G. Whayne, Sidney D. Fleischman, Earl W. Rogers
  • Patent number: 10639093
    Abstract: A surgical instrument including a housing, a shaft, an end effector assembly, a first electrical wire, and a wire guide. The shaft defines a lumen and extends distally from the housing. The end effector assembly is disposed at a distal end portion of the shaft and includes a first electrically-conductive tissue-treating surface. The first electrical wire extends from the housing, through the shaft, and into electrical communication with the first electrically-conductive tissue-treating surface. The electrical wire is adapted to connect to a source of energy and configured to supply energy to the first electrically-conductive tissue-treating surface. The wire guide is disposed within the housing and engaged about a proximal portion of the shaft within the housing. The wire guide is also configured to guide the first electrical wire from the housing into the shaft.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: May 5, 2020
    Assignee: COVIDIEN LP
    Inventors: David M. Keffeler, Kris Hess
  • Patent number: 10617459
    Abstract: An endovascular near critical fluid based cryoablation catheter for creating an elongate lengthwise-continuous lesion in tissue comprises an elongate shaft, a flexible distal tissue treatment section, and a distal tip. A plurality of flexible tubes extend through the distal treatment section to transport a near critical fluid to and from the distal tip. The distal treatment section is controllably deployed to match the contour of an anatomical region to be treated. In embodiments the distal treatment section includes a superelastic material and can assume a plurality of different shapes based on the distance ejected from an outer sleeve member. When the catheter is activated, heat is transferred between a target tissue and the distal treatment section of the catheter thereby creating the elongate lengthwise-continuous lesion in the tissue.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: April 14, 2020
    Assignee: Adagio Medical, Inc.
    Inventors: Xiaoyu Yu, Steven Kovalcheck, Alexei Babkin
  • Patent number: 10499820
    Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a system for measuring blood pressure. The system may include a pressure sensing guidewire including a pressure sensor and a first optical fiber extending proximally from the pressure sensor. The system may also include an optical connector cable including a distal connector capable of being coupled to the guidewire. The optical connector cable may include a second optical fiber that is capable of optically communicating with the first optical fiber. A coupler may be disposed within the distal connector and disposed between the first optical fiber and the second optical fiber.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: December 10, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Roger W. McGowan, Christopher Smuk, Peter Thornton, Jr.
  • Patent number: 10470763
    Abstract: A surgical instrument system comprising an end effector, a staple cartridge, a cutting member, an electric motor, a sensing system, and a control system is disclosed. The end effector comprises a proximal portion, a distal end, a first iaw, and a second iaw movable relative to the first iaw to clamp tissue between the first and second iaw. The cutting member is configured to move within a longitudinal channel of the staple cartridge. The electric motor is couplable to the cutting member and configured to drive the cutting member. The sensing system comprises a plurality of sensing circuits. Each sensing circuit comprises first and second sensing elements positioned adjacent the longitudinal channel. The control system is configured to determine impedances of the tissue at multiple locations along a staple line as the cutting member progresses distally within the longitudinal channel and automatically control a speed of the electric motor.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: November 12, 2019
    Assignee: Ethicon LLC
    Inventors: David C. Yates, Frederick E. Shelton, IV, James R. Giordano
  • Patent number: 10328253
    Abstract: A medical lead includes a coiled conductor portion that defines at least part of an outer surface of the lead and an expandable coiled fixation element that defines at least a part of the outer surface of the lead. The expandable coiled fixation element is configured to expand from a first dimension in a first state to a second dimension in a second state in a direction away from the coiled conductor portion. In some examples, the expandable coiled fixation element comprises a shape memory material.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: June 25, 2019
    Assignee: Medtronic, Inc.
    Inventor: Patrick D. Wells
  • Patent number: 10285648
    Abstract: The multifunctional, electrophysiological diagnostic catheter for electrocardiologic treatments includes a distal end, diagnostic rings, a balloon, a main channel, a manipulation handgrip, functional connection and internal channels. There is an internally-located open central channel, wherein inlet/outlet of an internal channel is located in the distal ring. There is a pumping channel for pumping up and pumping out of the occlusion-stabilizing balloon located after the diagnostic rings. There is a division of a central channel into two branches in the region of the catheter proximal end.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: May 14, 2019
    Assignee: MEDINICE S.A.
    Inventors: Sebastian Stec, Sanjeev Choudhary
  • Patent number: 10264981
    Abstract: A introducer is disclosed that includes an introducer sheath for introducing a catheter into a blood vessel at an insertion point, a plurality of electrodes on the introducer sheath, a flush line coupled to the introducer sheath including a proximal end and a distal end. In addition, the introducer includes an impedance assessment unit coupled to the flush line between the proximal end and the distal end and electrically coupled to the electrodes. The impedance assessment unit is configured to inject a predetermined current or voltage into a first of the plurality of electrodes and measure a resulting voltage or current, respectively, from a second of the plurality of electrodes.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: April 23, 2019
    Assignee: Saranas, Inc.
    Inventors: Christopher Alexander Arevalos, Mehdi Razavi, Matthew DeNardo, Serge Roux, Joe Bailey, Arun Venkatasubramanian
  • Patent number: 10251703
    Abstract: Treatment systems are provided, which comprise a treatment element applying a treatment to a tissue, a stimulation element optically stimulating nerves in the tissue, a sensing unit sensing an electrical signal produced by nerves in the tissue in response to the optical stimulation, and a control unit controlling the application of the treatment according to the sensed signal. The systems and methods are used to avoid damaging nerves by sensing them during operation and immediately before local treatment application and preventing energy emission when the treatment tool is too close to specified nerves. Additional electric stimulation may be provided to enable avoidance of nerve damages on a larger scale, the treatment may be applied by a cold laser, and the control unit may control the treatment in realtime and in a closed loop and immediate prevent further treatment upon sensing optically stimulated nerves.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: April 9, 2019
    Assignee: NERVESENSE LTD.
    Inventors: Dan David Albeck, Tzachi Itzhak Sabati
  • Patent number: 10124152
    Abstract: A system and method for perfusing a liquid medicament into tissue of a patient requires a catheter having a distal barrier and a proximal barrier mounted on the catheter. A perfusion section is formed into the catheter between these barriers. By way of example of a typical operation, the catheter is advanced through the vasculature of a patient and into the coronary sinus. Advancement continues until the barriers of the catheter are positioned to straddle the ostium of the left atrial vein. As so positioned, a perfusion chamber is established in the coronary sinus between the barriers. Also, the perfusion chamber is positioned for fluid communication with the left atrial vein. Liquid medicament can then be transferred from a source into the perfusion chamber for perfusion of the medicament into tissue of the atrial vein.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: November 13, 2018
    Assignee: GUY P. CURTIS AND FRANCES L. CURTIS TRUST
    Inventor: Guy P. Curtis
  • Patent number: 10111768
    Abstract: A system and method for positioning sheaths into the Coronary Sinus using a guiderail catheter.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: October 30, 2018
    Assignee: MWEST, LLC
    Inventor: Michael B. West
  • Patent number: 10010364
    Abstract: Devices and methods that regulate the innervation of the kidney by detection and modification of the aorticorenal ganglion. Devices for percutaneous detection and treatment of the aorticorenal ganglion via a blood vessel to modify renal sympathetic activity.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: July 3, 2018
    Assignee: Halcyon Medical, Inc.
    Inventor: Douglas C. Harrington
  • Patent number: 9993160
    Abstract: A medical system may include a shaft member and a structure physically coupled to the shaft member. A portion of the shaft member may be sized to be delivered through a bodily opening leading to a bodily cavity. The structure may include at least two flexible couplings, each flexible coupling extending transversely from an intermediate portion of a respective one of at least two elongate members of the structure. The flexible coupling extending transversely from the intermediate portion of a first one of the at least two elongate members forms at least a part of a first closed loop arranged to receive a portion of the flexible coupling of a second one of the at least two elongate members therethrough to limit a spacing between the intermediate portions of the first and the second ones of the at least two elongate members.
    Type: Grant
    Filed: December 22, 2014
    Date of Patent: June 12, 2018
    Assignee: KARDIUM INC.
    Inventors: Aldo Antonio Salvestro, John Andrew Funk, Kelly Wilson Watkinson, Saar Moisa
  • Patent number: 9974956
    Abstract: Methods, systems, and apparatus for quantifying the quality of a fiducial time marker for a candidate heart beat, quantifying the quality of a candidate heart beat, or determining a time of beat sequence of the patient's heart. A fiducial time marker is obtained for a candidate heart beat. A quality index of said candidate heart beat is set to a first value. The candidate heart beat is tested with at least one beat validity test. At least a second value is added to said quality index of said candidate heart beat if said candidate heart beat passes said at least one beat validity test. The candidate heart beat is tested with at least a second heart beat validity test. At least a third value is added to said quality index of said candidate heart beat if said candidate heart beat passes said at least second heart beat validity test.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: May 22, 2018
    Assignee: Cyberonics, Inc.
    Inventors: Mark G Frei, Ivan Osorio
  • Patent number: 9923313
    Abstract: An electrical connector includes a male insertion piece and a female insertion piece. The male insertion piece has an insulation base, an insulation tube being hollow and formed on one end of the insulation base, an outer electrode securely mounted around the insulation tube, and a conductive needle mounted in the insulation tube. The female insertion piece has an insulation sleeve having a guiding slot for the insulation tube to be inserted therein, an outer connection electrode mounted inside the insulation sleeve and mounted around the outer electrode, and an inner connection electrode having a first conductive part abutting against a top portion of the conductive needle and at least two second conductive parts holding two lateral portions of the conductive needle. When the male insertion piece engages the female insertion piece, there are at least three contact positions forming a firm and stable triangular connection.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: March 20, 2018
    Assignee: Jetmax Lighting Industrial Co., Limited
    Inventor: Ping Yang
  • Patent number: 9918653
    Abstract: The invention relates to electrophysiology catheter systems and their use, such as in an MRI environment, and in particular to analysis of electric signals from such. An electrophysiology (EP) catheter with a plurality of electrically isolated electrode segments arranged in longitudinally spaced bands around the catheter is used to detect electric signals. A workstation receives the electrical signals which are then processed by a processing unit. Electric signals from electrode segments can be used to determine roll angle information of the catheter in relation to patient anatomy by determining signals from electrode segments in contact with tissue. Also, electric signals can be used to extract a reference signal that can be used to correct for gradient induced artifacts.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: March 20, 2018
    Assignee: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Oliver Lips, Bernd David, Sascha Krueger, Steffen Weiss
  • Patent number: 9918776
    Abstract: A multi-pole synchronous pulmonary artery radiofrequency ablation catheter may comprise a control handle, a catheter body and an annular ring. One end of the catheter body may be flexible, and the flexible end of the catheter body may be connected to the annular ring. The other end of the catheter body may be connected to the control handle. A shape memory wire may be arranged in the annular ring. One end of the shape memory wire may extend to an end of the annular ring and the other end of the shape memory wire may pass through a root of the annular ring and be fixed on the flexible end of the catheter body. The annular ring may be provided with an electrode group. The device possesses advantages of simple operation, short operation time and controllable precise ablation. The device can be used to treat pulmonary hypertension with pulmonary denervation.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: March 20, 2018
    Assignee: Pulnovo Medical (Wuxi) Co., Ltd.
    Inventor: Shaoliang Chen
  • Patent number: 9808342
    Abstract: A sizing device for a collapsible prosthetic heart valve, the sizing device includes a collapsible and expandable balloon having a proximal end, a distal end. At least one microelectromechanical sensor is coupled to the balloon, the at least one sensor being capable of measuring information related to size and stiffness of tissue.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: November 7, 2017
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Ramji T. Venkatasubramanian, Peng Peng
  • Patent number: 9775991
    Abstract: A system to generate and sense electrical energy to and from tissue within a mammalian body. The system includes a flexible shaft and an electrical generator disposed on or embedded within the flexible shaft. Radially displaceable arcuate arm members forming electrodes are displaceable responsive to actuation of the electrical generator.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: October 3, 2017
    Inventors: A-Hamid Hakki, A-Hadi Hakki
  • Patent number: 9713730
    Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material proximate to a body lumen, often of stenotic material or tissue in the luminal wall of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage the luminal wall when the structure expands. Feedback using one or parameters of voltage, current, power, temperature, impedance magnitude, impedance phase angle, and frequency may be used to selectively control the delivery of energy.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: July 25, 2017
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Prabodh Mathur, Meital Mazor, Dolores Perez
  • Patent number: 9713431
    Abstract: Aspects of the present disclosure are directed to detecting Atrial Fibrillation (AF). As may be implemented in accordance with one or more embodiments, a time series of inter-beat intervals is computed from a recording of activity of a beating heart. The time series is decomposed into subcomponents, and an envelope of at least one of the subcomponents is computed. The presence of atrial fibrillation (AF) is detected based upon characteristics of the envelope that are indicative of AF.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: July 25, 2017
    Assignee: VivaQuant LLC
    Inventors: Marina Brockway, Brian Brockway
  • Patent number: 9655560
    Abstract: A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measurement and delivery of therapy.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 23, 2017
    Assignee: MC10, Inc.
    Inventors: Roozbeh Ghaffari, Gilman Callsen, William J. Arora, Benjamin Schlatka
  • Patent number: 9597495
    Abstract: The invention is a method of identifying a preferred location for an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject and array location to array location. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the preferred location. Alternatively, electrode height may be measured directly to predict the preferred location.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: March 21, 2017
    Assignee: Second Sight Medical Products, Inc.
    Inventors: Robert J. Greenberg, Jone Fine, Arup Roy, Matthew J. McMahon, Mark S. Humayun, James David Welland, Alan M. Horsager, Dao Min Zhou, Amy Hines, Sumit Yadav, Rongqing Dai
  • Patent number: 9526432
    Abstract: The present invention is a device for providing an enhanced bioelectric sensing probe tip to facilitate locating and obtaining a bioelectric resistance value from a patient for therapeutic and/or diagnostic purpose. One embodiment of the present invention is a probe tip that comprises a uniform array of bristles that contacts a surface layer of a patient's skin to enable the bioelectric probe tip to locate and obtain a bioelectric resistance value from the patient. Another embodiment of the invention is to provide a probe tip cover that prevents foreign material from contaminating the probe tip and to assist in attaching the probe tip to a probe.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: December 27, 2016
    Assignee: Fresh Medical Laboratories, Inc.
    Inventor: Phillip Dietz
  • Patent number: 9486206
    Abstract: Medical devices, systems, and methods reduce the distance between two points in tissue, often for treatment of congestive heart failure and often in a minimally invasive manner. An anchor is inserted along an insertion path through a first wall of the heart. An arm of the anchor is deployed and rotationally positioned according to a desired alignment. Application of tension to the anchor may draw the first and second walls of the heart into contact along a desired contour so as to effect a desired change in the geometry of the heart. Additional anchors may be inserted and aligned with the first anchor to close off a portion of a ventricle such that the ventricle is geometrically remodeled and disease progression is reversed, halted, and/or slowed.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: November 8, 2016
    Assignee: BioVentrix, Inc.
    Inventors: Lon S. Annest, Claudio Argento, William Butler, Ernest Heflin
  • Patent number: 9480523
    Abstract: The systems and methods of the present disclosure calibrate impedance loss model parameters associated with an electrosurgical system and compensate for impedance losses in an electrosurgical system using the calibrated impedance loss model parameters. A computer system stores voltage and current sensor data for different test loads and calculates impedance values for each test load. The computer system predicts a phase value for each test load using a respective load impedance value. The computer system back calculates impedance loss model parameters based upon the voltage and current sensor data, the predicted phase values, and the impedance values of the test loads. During operation, the electrosurgical device senses a voltage and a current, predicts a phase value based upon the sensed voltage and current, and calculates metrics at the tissue site based upon the sensed voltage and current, the predicted phase value, and the impedance loss model parameters.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: November 1, 2016
    Assignee: COVIDIEN LP
    Inventor: Donald W. Heckel
  • Patent number: 9439714
    Abstract: A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: September 13, 2016
    Assignee: Atricure, Inc.
    Inventors: James G. Whayne, Sidney D. Fleischman, Earl Wayne Rogers
  • Patent number: 9345540
    Abstract: A catheter including a proximal end and a distal end. An expandable element coupled to the distal end is included, the expandable element including a proximal portion and a distal portion, the expandable element defining an exterior surface. A first plurality of electrodes coupled to the exterior surface of the distal portion of the expandable element are included, each of the first plurality of electrodes being selectively operable to transmit unipolar radiofrequency energy. A second plurality of electrodes coupled to the exterior surface of the proximal portion of the expandable element are included, each of the second plurality of electrodes being selectively operable to transmit bipolar radiofrequency energy.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 24, 2016
    Assignee: Medtronic Ablation Frontiers LLC
    Inventors: George D. Mallin, Timothy G. Laske, Joseph Allen Knight
  • Patent number: 9289132
    Abstract: A system, device and method are presented for utilizing stretchable active integrated circuits with inflatable bodies. The invention allows for such operative features to come into direct contact with body structures, such as the inner wall of a lumen. Such direct contact increases accuracy of measurement and delivery of therapy.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: March 22, 2016
    Assignee: MC10, Inc.
    Inventors: Roozbeh Ghaffari, Gilman Callsen, William J. Arora, Benjamin Schlatka
  • Patent number: 9242070
    Abstract: A system and method for quickly detaching an implant and for locating the detachment zone of a detachable implant. A sensor determines a sudden change in the local environment as the sensor passes from within a microcatheter to being exposed to the vasculature. The sensor may be a temperature sensor, ultrasonic sensor, pressure sensor or the like. If the detachable implant assembly uses a heater coil to detach the implant, the heater coil may be used as a sensor. Additionally, the implant itself may be used as a sensor if a change in electrical resistance is detectable as the implant exits the microcatheter and changes shape.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: January 26, 2016
    Assignee: MicronVention, Inc.
    Inventor: Tai D. Tieu
  • Publication number: 20150148645
    Abstract: A microlead has a distal active portion formed by a microcable including an electrically conductive core coated with an insulation layer, with a plurality of exposed areas forming the stimulation electrodes. The microcable has a three-dimensional preshape inscribed in a cylindrical envelope volume so as to match the target vessel wall. The microcable includes a plurality of exposed areas regularly distributed over the circumference of the cylindrical envelope volume considered in axial projection, the exposed zones extending only over an angular sector of the microcable considered in cross section, said angular sector facing the outside of the envelope volume of the preshape.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventors: Willy Régnier, Philippe d'Hiver
  • Publication number: 20150119674
    Abstract: An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall.
    Type: Application
    Filed: October 25, 2013
    Publication date: April 30, 2015
    Applicant: Ablative Solutions, Inc.
    Inventors: David R. Fischell, Tim A. Fischell, Vartan Ghazarossian, Steven Almany
  • Patent number: 9014822
    Abstract: A pacing lead for a left cavity of the heart, implanted in the coronary system. This lead (24) includes a lead body with a hollow sheath (26, 28) of deformable material, having a central lumen open at both ends, and at least one telescopic microcable (42) of conductive material. The microcable slides along the length of the lead body and extends beyond the distal end (32) thereof. The party emerging beyond the distal end is an active free part (34) comprising a plurality of distinct bare areas (36, 38, 50, 50?, 50?), intended to come into contact (40) with the wall of a target vein (22) of the coronary system (14-22), so as to form a network of stimulation electrodes electrically connected together in parallel. The microcable further comprises, proximally, a connector to a generator of active implantable medical device such as a pacemaker or a resynchronizer.
    Type: Grant
    Filed: August 6, 2013
    Date of Patent: April 21, 2015
    Assignee: Sorin CRM S.A.S.
    Inventor: Jean-François Ollivier
  • Patent number: 8989834
    Abstract: Apparatus, systems and methods employing a contact lens that generates information indicative of a hydration level of an eye in which the lens is worn, are provided. In some aspects, a contact lens includes a substrate that forms at least part of a body of the contact lens and a hydration component that generates information associated with a hydration level of an eye in which the contact lens is worn.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: March 24, 2015
    Assignee: Google Inc.
    Inventors: Harvey Ho, Babak Amirparviz
  • Publication number: 20150051467
    Abstract: An implantable medical device system and associated method receive a signal from an implantable sensor operatively positioned relative to a vein, the signal being responsive to changes in a diameter of the vein. A diameter of the vein is determined in response to the sensor signal and used in estimating central venous pressure (CVP).
    Type: Application
    Filed: August 25, 2014
    Publication date: February 19, 2015
    Inventors: Giorgio Corbucci, Josephus P.A. Smit, Johannes S. Van Der Veen, Geert Van Lembergen, Marinus C.J. Verschelling
  • Patent number: 8945110
    Abstract: An electrophysiology catheter includes an elongate catheter body having an elastically-deformable distal region predisposed to assume a spiral shape and a first plurality of electrodes disposed thereon. Each of the first plurality of electrodes includes an electrically active region limited to the inner surface of the spiral shape for use in non-contact electrophysiology studies. A second plurality of electrodes may also be disposed on the distal region interspersed (e.g., alternating) with the first plurality of electrodes, with each of the second plurality of electrodes having an electrically active region extending into the outer surface of the spiral shape for use in contact electrophysiology studies. The distal region may be deformed into a straight configuration for insertion into and navigation through the patient's vasculature, for example via use of a tubular introducer. As the distal region deploys beyond the distal end of the introducer, it resumes the spiral shape.
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: February 3, 2015
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Jeffrey M. Fish, Sacha C. Hall, Theodore A. Johnson
  • Patent number: 8939153
    Abstract: A transponder string comprising multiple transponders is configured for injection into human tissue. In one embodiment, the transponders are sized to move through a needle for injection into the human tissue. Positions of the transponders with reference to one another may be maintained by coupling the transponders via a filament, adhesive backed substrate, shrink tubing, and/or any other suitable substrate. The transponders are configured to transmit data to a mobile computing device, e.g., a wand, smart phone or wireless tablet positioned outside the human tissue such that positions of the transponders are determinable, e.g., during an excision surgery.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 27, 2015
    Assignee: Health Beacons, Inc.
    Inventors: Murray A. Reicher, Robert Petcavich
  • Patent number: 8939970
    Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.
    Type: Grant
    Filed: February 29, 2012
    Date of Patent: January 27, 2015
    Assignee: Vessix Vascular, Inc.
    Inventors: Corbett W. Stone, Michael F. Hoey, Tom A. Steinke, Raphael M. Michel, Arthur G. Blanck, Marlene Kay Truesdale, Bret Herscher
  • Patent number: 8934956
    Abstract: An intravascular electrode device for use in neuromodulation includes an anchor expandable from a radially compressed position to a radially expanded position. A lead extends from the anchor and has at least one conductor extending through it. A flex circuit is coupled to the anchor and comprises a flexible insulative substrate, a plurality of electrodes carried by the substrate, and a plurality of conductive traces carried by the substrate, each trace electrically coupled to an electrode and a conductor. Expansion of the anchor within a blood vessel biases the electrodes into contact with the surrounding blood vessel wall. An exemplary anchor includes a first portion having expansion forces sufficient to bias the electrodes against the vessel wall for mapping and chronic stimulation, and a second portion having greater radial expansion forces sufficient to chronically engage the vessel wall once an optimal electrode location has been selected.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: January 13, 2015
    Assignee: Interventional Autonomics Corporation
    Inventors: Richard A. Glenn, Jeffrey A. Smith, Geoffrey A. Orth, Kevin Holbrook, Michael S. Williams
  • Patent number: 8929969
    Abstract: A catheter assembly for use in an anatomy can include an elongated body, which can have a proximal end and a distal end. The body can also define a lumen from the proximal end to the distal end. The assembly can include at least one electrode, which can be coupled to the distal end to sense an electrical activity within the anatomy. The assembly can include a core wire, which can be received within the lumen from the proximal end to the distal end. The core wire can be configured to move the distal end from a first configuration to a second configuration. The assembly can also include a necked portion, which can be formed between the proximal end and the distal end to provide increased stiffness to the distal end of the body.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: January 6, 2015
    Assignee: Medtronic Ablation Frontiers LLC
    Inventors: Edward M. Gillis, Christine Beltran
  • Patent number: 8920414
    Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 30, 2014
    Assignee: Vessix Vascular, Inc.
    Inventors: Corbett W. Stone, Michael F. Hoey, Tom A. Steinke, Raphael M. Michel, Arthur G. Blanck, Marlene Kay Truesdale, Bret Herscher
  • Patent number: 8909316
    Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: December 9, 2014
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventor: Kok-Hwee Ng
  • Publication number: 20140336476
    Abstract: A sensor is provided available for continuous monitoring of regional blood flow in a tissue, including cerebral tissue. Methods of monitoring regional blood flow using the sensor as well as systems and computer readable medium therefor are also provided.
    Type: Application
    Filed: October 26, 2012
    Publication date: November 13, 2014
    Applicant: THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
    Inventor: Chunyan Li
  • Publication number: 20140288667
    Abstract: An intravascular device for placement within an animal vessel, the intravascular device being adapted to at least one of sense and stimulate activity of neural tissue located outside the vessel proximate the intravascular device.
    Type: Application
    Filed: October 3, 2012
    Publication date: September 25, 2014
    Inventor: Thomas James Oxley