Abstract: A skin-adorned physiological or biochemical sensing device is disclosed herein. The device preferably comprises a first substrate and a second substrate. The first substrate comprises an array of solid microneedles designed to penetrate a biological interface to access a physiological fluid or tissue. Each microneedle is capable of electrical interface with the physiological fluid or tissue. The second substrate comprises integrated circuitry designed to transduce at least one signal produced by an electrophysiological or electrochemical reaction. A sensing device is formed that is capable of interpreting the signal arising from the electrophysiological or electrochemical reaction to ascertain the level of some physiological or biochemical entity.

Abstract: In a secondary batter, dead spaces between a wound electrode body and the inner peripheral surfaces of a rectangular battery case are made small. The secondary battery includes a wound electrode body in which a positive electrode sheet, a negative electrode sheet, and a separator interposed between the positive electrode sheet and the negative electrode sheet are superimposed and wound around a winding axis, and a rectangular battery case that houses the wound electrode body. The wound electrode body has a first flat surface, a second flat surface, a third flat surface, and a fourth flat surface positioned on the outer peripheral surfaces around the winding axis. The first flat surface and the second flat surface face each other with the winding axis interposed therebetween. The third flat surface and the fourth flat surface face each other with the winding axis interposed therebetween.

Abstract: A catheter for use in a patient's heart, especially for mapping a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal a mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for single-handed manipulation of various control mechanisms that can deflect the intermediate section and contract the mapping assembly by means of a deflection control assembly and a linear control assembly. The deflection control assembly has a deflection arm and a rocker member. The linear control assembly has a linear control member, an inner rotational member and a cam. A pair of puller members are responsive to the deflection control assembly to bi-directionally deflect the intermediate section. A third puller member is responsive to the linear control assembly to contract the generally circular portion of the mapping assembly.

Abstract: A system for continuously humidifying a textile electrode during its use by a human is disclosed. The electrode can be part of a garment or textile where the textile electrode is positioned against the skin. A reservoir positioned against the electrode and opposite the user's skin can be made from a material with hydrophilic and hydrophobic properties, such as natural wool or a skincore material. The reservoir receives and retains moisture from the user's skin through the electrode, as well as from a pre-wetting of the exposed user-facing side of the electrode. A seal can surround the reservoir and the electrode, with the seal extending beyond electrode. The seal can be a patch with heat activated adhesive at the edge to flow the textile to form a moisture barrier around the electrode. An electrical contact on the electrode can connect conductive wires from outside the seal to the electrode.

Abstract: An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

Abstract: A method includes forming a film, forming a first pattern of two or more vias at least partially through the film, attaching the film to a first support structure, the first support structure comprising an adhesive layer formed over a first carrier, wherein attaching the film to the first support structure comprises bonding a first surface of the film to the adhesive layer of the first support structure, wherein the film is stretchable in at least a first direction along the first surface, and wherein the first carrier maintains the first pattern of vias within a given threshold distortion following a given process conducted after attaching the film to the first support structure.

Abstract: A wearable medical device comprises a harness, a therapy electrode and an electrocardiogram (ECG) sensing electrode included within the harness, an audio transducer coupled to the therapy electrode or to the ECG electrode and configured to monitor heart sounds of a user of the wearable therapeutic device, and a controller configured to receive signals from the audio transducer regarding the heart sounds of the user and to transmit data regarding the heart sounds to an external system for processing and analysis.

Abstract: An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

Abstract: A flexible dry electrode comprises a multi-walled carbon nanotube (MWCNT)/polydimethylsiloxane (PDMS) composite. The flexible dry electrode may be utilized for monitoring electrocardiogram (ECG) signals. The dry ECG electrode may be fabricated by screenprinting silver (Ag) ink on flexible polyethylene terephthalate (PET) substrate, followed by bar coating of a MWCNT/PDMS composite.

Abstract: A steering-wheel grip sensor includes: a driven electrode having a planar shape and extending along a rim of a steering wheel; a sensor electrode having a planar shape and opposed to the driven electrode; a sine-wave generator that supplies a sinusoidal voltage to the driven electrode; a charge amplifier that includes a feedback capacitive element, detects a change in an amount of charge generated according to capacitance of the sensor electrode, and outputs the change in the amount of charge as a change in a voltage; a multiplication processor that multiplies the sinusoidal voltage by an output voltage from the charge amplifier; an integrator that smooths, by integration, a result of multiplication by the multiplication processor; and a grip determiner that determines whether the steering wheel is gripped, according to a level of the result smoothed.

Abstract: An electrocardiography patch is provided. A backing includes two rounded ends connected by a middle section that is narrower than the two rounded ends. An electrode is positioned on a contact surface of the backing on each rounded end. A circuit trace is electrically coupled to each of the electrodes. A battery is positioned on an outer surface of the backing, opposite the contact surface, on one of the rounded ends.

Abstract: A physiological signal sensing system and a physiological signal sensing method are provided. The physiological signal sensing system includes a signal processing device and a physiological signal sensing device having a plurality of sensing electrodes. The sensing electrodes are used to contact the skin of an organism to sense a plurality of physiological signals. The signal processing device is coupled to the physiological signal sensing device to receive the physiological signals, compares these physiological signals with the reference physiological signal pattern to obtain a comparison result, selects a selected electrode pair from the sensing electrodes based on the comparison result, and uses the selected electrode pair to perform physiological signal measurement on the organism during a normal operation period.

Abstract: A system, device, and method for transcutaneous nerve stimulation such as facial nerve stimulation, and in particular, to using transcutaneous nerve stimulation for artificially eliciting eye blink, such as with humans with acute facial paralysis (Bell's palsy or Dry Eye syndrome), is disclosed. A battery-operated wearable device may employ a pulse generator for periodically and automatically generating bursts train of asymmetrical Bi-Phasic square pulses. The output pulses are fed to two electrodes that are attached to the skin of the treated person to stimulate the facial nerve for eliciting blinking at a rate that mimics normal blinking operation. The device may include a sensor and a wireless connection, and the parameters of, or the activation of, the generated bursts may be controlled by the sensor output, by human user control, or by data received from the wireless network. Further, the device may transmit status to the wireless network.

Abstract: A first electrode and a second electrode are attached to a subject. A processor module acquires physiological information of the subject based on biopotential that are detected by the first electrode and the second electrode, respectively. A housing has a battery housing member for housing a primary battery which supplies an electric power to the processor module. The processor module is attachable to and detachable from the housing.

Abstract: Physiological monitoring can be provided through a lightweight wearable monitor that includes two components, a flexible extended wear electrode patch and a reusable monitor recorder that removably snaps into a receptacle on the electrode patch. The wearable monitor sits centrally on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline, with its unique narrow “hourglass”-like shape, significantly improves the ability of the wearable monitor to cutaneously sense cardiac electrical potential signals, particularly the P-wave and the QRS interval signals indicating ventricular activity in the ECG waveforms. In particular, the ECG electrodes on the electrode patch are tailored to be positioned axially along the midline of the sternum for capturing action potential propagation in an orientation that corresponds to the aVF lead used in a conventional 12-lead ECG that is used to sense positive or upright P-waves.

Abstract: Disclosed are an adhesive transparent electrode and a method of fabricating the same. More particularly, an adhesive transparent electrode according to an embodiment of the present disclosure includes a substrate and an adhesive silicone-based polymer matrix, in which a metal nanowire network is embedded, deposited on the substrate, wherein the adhesive silicone-based polymer matrix includes a silicone-based polymer including a silicone-based polymer base and a silicone-based polymer crosslinker; and a non-ionic surfactant.

Abstract: A system and an apparatus for guiding an instrument may be provided, the apparatus comprising a main body; a holding member for holding an instrument, the holding member coupled to the main body; and one or more actuating members configured to effect movement of the holding member such that said movement of the holding member is capable of providing rotational movement of an instrument about a pivot point external the apparatus. The holding member may preferably be configured to co-operate with a compliance device, said compliance device capable of holding the instrument.

Abstract: There are provided methods and systems for making or repairing a specified part. For example, there is provided a method for creating an optimized manufacturing process to make or repair the specified part. The method includes receiving data from a plurality of sources, the data including as-designed, as-manufactured, as-simulated, and as-tested data relative to one or more parts similar to the specified part. The method includes updating, in real time, a surrogate model corresponding with a physics-based model of the specified part, wherein the surrogate model forms a digital twin of the specified part. The method includes further updating the surrogate model with a model of manufactured variance associated with at least one of inspection and in-operation data of a similar part. The method includes executing, based on the digital twin, the optimized manufacturing process to either repair or make the specified part.

Abstract: A system and method for a multichannel voltage recording device is described. A multichannel voltage recording device comprises at least three electrodes disposed across a conductive material. The electrodes are configured to be coupled to a skin of a user. A frame comprises the conductive material that is configured to receive a driven right leg (DRL) signal based on the voltage signals from the at least three electrodes.

Abstract: Embodiments of the present disclosure relate to monitoring one or more physiological parameters of a subject using a multilayer wearable device. In an embodiment, a multilayer wearable device is configured to be attached to a subject. The multilayer wearable device comprises a substrate having multiple layers including a first portion connected to a second portion. The first portion has a first side and a second, opposite side. And the second portion has a first side and a second, opposite side. The first side of the first portion is configured to be attached to the subject and the second portion is arranged on top of the first portion such that the first side of the second portion is disposed adjacent the second side of the first portion. And, the wearable device includes one or more electrical components configured to sense a physiological parameter of the subject.

Abstract: Flexible electrical devices comprising electrode layers on softening polymers and methods of manufacturing such devices, including lift-off processes for forming electrodes on softening polymers, processes for forming devices with a patterned double softening polymer layer, and solder reflow processes for forming electrical contacts on softening polymers.

Abstract: An electromyography (EMG) device according to an aspect of the present disclosure includes a main circuit board having opposing first and second faces. A plurality of first connectors of a first type are provided on the first face, and a plurality of input contacts are provided on the second face. An EMG circuit is provided on the main circuit board. The EMG circuit is configured to utilize the input contacts as inputs to obtain an EMG input signal, and process the EMG input signal to provide an EMG output signal that is based on, but different from, the EMG input signal. For each of the input contacts, there is no conductive path directly between the input contact and any of the first connectors.

Abstract: A wireless intraluminal device (102) and an associated system for treating and diagnosing patients are provided. In one embodiment, the wireless intraluminal device (102) includes a flexible elongate member (158) including a proximal portion (106) and a distal portion (108); a sensor assembly (116) coupled to the distal portion of the flexible elongate member; a cable (117) coupled to the sensor assembly and extending along the flexible elongate member; and a wireless transceiver (252) positioned within the flexible elongate member, wherein the wireless transceiver is in communication with the sensor assembly via the cable. A wireless communication component (104) wirelessly transmits a sensor measurement collected by the sensor assembly to a sensor measurement processing system (132) via a wireless link (150) for physiological data generation at the sensor measurement processing system.

Abstract: A system for detecting salt ion concentration, comprising a device further comprising a sensor having a carbon printed electrode on a flexible substrate with adhesive on one side (backside) and the circuit electronics to generate pulse signal stimuli and measure salt concentrations to determine hydration level of a person or a living being, wherein the device is a wearable device. The electrode can be made into different shapes changing the area as necessary, since it is a carbon printed electrode and is flexible.

Abstract: This document describes an electrode assembly for use with a defibrillator, the electrode assembly comprising at least one electrode including a first surface that can be affixed to either of a pediatric patient and an adult patient and a second surface, wherein a majority of the second surface includes pictorial instructions related to use of the electrode assembly; and a chest compression sensor attached to the at least one electrode, wherein the at least one electrode is configured to be used on an adult patient when the electrode assembly is in a first orientation, and wherein the at least one electrode is configured to be used on a pediatric patient when the electrode assembly is in a second orientation.

Abstract: An ambulatory electrocardiography monitor is provided. The monitor includes a housing adapted to couple to a monitoring patch that includes electrocardiographic electrodes; and electronic circuitry provided within the housing. The electronic circuitry includes an electrocardiographic front end circuit; the microcontroller configured to: execute a power up sequence upon the housing coupling to the patch; after the execution of the power-up sequence, retrieve from the monitoring patch an identifier associated with the patch and a password for accessing results of a physiological monitoring conducted using the patch; read samples of the electrocardiographic signals, buffer the samples of the electrocardiographic signals, compress the buffered samples of the electrocardiographic signals, buffer the compressed samples of the electrocardiographic signals, and write-the buffered samples into a memory in association with the password and the identifier; and the memory electrically interfaced with the microcontroller.

Abstract: A self-authenticating electrocardiography and physiological sensor monitor is provided. An electrode patch includes an elongated strip and electrodes exposed on each end. A receptacle is adhered to the elongated strip and includes electrical pads. Circuit traces are electrically coupled to the electrocardiographic electrodes and the electrical pads. A monitor recorder having a sealed housing is adapted to be secured into the receptacle. Circuitry within the housing includes a microcontroller with a private key. A copy of the private key is stored on the patch. Self-authentication is performed each time the monitor recorder is inserted into a new patch by challenging the patch using a code hashed with the private key and by receiving a response from the patch in reply to the challenge. A front end circuit senses electrocardiographic signals via electrodes on the patch when the response received by the microcontroller is positive, until the electrode patch expires.

Abstract: An electrocardiography patch is provided. The patch includes a backing and at least two electrocardiographic electrodes each positioned on the backing, across from another of the electrocardiographic electrodes, to capture electrocardiographic signals. A flexible circuit includes a pair of circuit traces electrically coupled to the electrocardiographic electrodes. A wireless transceiver communicates at least a portion of the electrocardiographic signals.

Abstract: Provided is a body composition analyzing apparatus by using an impedance of a half of an upper body. According to an example embodiment, the body composition analyzing apparatus includes a first electrode part which comes into contact with a half of an upper body of an object, a second electrode part which comes into contact with the half of the upper body, a measurer configured to apply a current to each of the electrode parts, and to measure an impedance of the half of the upper body of the object by measuring a voltage of each of the electrode parts, and an analyzer configured to analyze body composition of the object based on the measured impedance of the half of the upper body.

Abstract: An apparatus is disclosed. The apparatus has a lighting component, an energy storage assembly electrically connected to the lighting component, and a housing. The energy storage assembly is a Graphene stack battery that includes a Graphene strip. The energy storage assembly is disposed on or in the housing. The lighting component is disposed on or in the housing. The Graphene strip is a folded Graphene strip with a folded serpentine shape having intervening insulation strips disposed between a plurality of folded Graphene strip portions with leads at the two ends of the Graphene strip.

Abstract: A tag is provided that includes a battery having a printed anode and cathode. A printed circuit connection layer is formed in one of the anode or the cathode. A printed antenna is formed in one of the anode or the cathode. A low-power transmitter coupled to the circuit connection layer.

Abstract: An ambulatory electrocardiography monitor is provided. The monitor includes a housing adapted to couple to a monitoring patch that includes electrocardiographic electrodes; and electronic circuitry provided within the housing. The electronic circuitry includes an electrocardiographic front end circuit; the microcontroller configured to: execute a power up sequence upon the housing coupling to the patch; after the execution of the power-up sequence, retrieve from the monitoring patch an identifier associated with the patch and a password for accessing results of a physiological monitoring conducted using the patch; read samples of the electrocardiographic signals, buffer the samples of the electrocardiographic signals, compress the buffered samples of the electrocardiographic signals, buffer the compressed samples of the electrocardiographic signals, and write-the buffered samples into a memory in association with the password and the identifier; and the memory electrically interfaced with the microcontroller.

Abstract: On-body analyte sensors may be designed for extended wear to provide ongoing measurement of physiological analyte levels. However, on-body analyte sensors may be susceptible to damage or dislodgment during wear due to routine interactions that occur with one's surroundings. Guard rings may be adapted to protect on-body analyte sensors from such interactions. Guard rings may comprise an annular body comprising an inner perimeter face, an outer perimeter face, a top edge, and a bottom face adapted for contacting a tissue surface. The inner perimeter face is shaped to circumferentially surround a sensor housing of an on-body analyte sensor. At least a portion of the outer perimeter face defines a chamfered surface extending between the top face and the bottom face. Adhesive pads or strips may further be engaged with the guard rings and aid in securing the guard rings to a surface, such as skin.

Abstract: Herein described is an osseointegrated interface device for engagement with an amputated limb including the skin comprising: a cap portion engageable with an osseointegrated device; wherein the cap portion comprises a surrounding flange; and wherein in use the surrounding flange receives the skin of the amputated limb at a distance spaced from the osseointegrated device.

Abstract: A system for electrically coupling a garment to a mating object and manufacture method thereof, the system comprising: a fabric interlayer of the garment including a set of ports; an electronics substrate having a first surface adjacent to a second side of the fabric interlayer and including a set of vias through a thickness of the electronics substrate, aligned with the set of ports, and a set of contacts at a second surface opposing the first surface; a mount assembly having a third surface adjacent to the second surface of the electronics substrate and including a set of holes aligned with the set of vias and the set of ports, as well as a set of openings that correspond to and receive portions of the set of contacts, and a fourth surface opposing the third surface and defining a cavity configured to receive and electrically interface the mating object to the electronics substrate; and a set of fasteners that 1) compress the backing plate, the fabric interlayer, the electronics substrate, and the mount ass

Abstract: Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

Abstract: An electrode is supported on a prosthetic liner to communicate electrically with a residual limb. A housing is fixed to the liner, and is receivable in a socket in an installed position. A processor is installed in the housing in communication with the electrode. Electrical signal contacts are exposed at a distal end of the housing for contacting electrical signal contacts in the socket. The housing defines a ground current path that communicates with a ground contact in the socket.

Abstract: The present invention relates to a neural implant comprising a biomaterial having an outer surface with a stochastic nanoroughness (Rq), and the application of said stochastic nanoroughness in the diagnosis and/or treatment of a neurological disorder, such as, for example, Parkinson's disease, Alzheimer's disease, glioblastoma and/or for disrupting and/or preventing glial scars in the context of mammalian mechanosensing ion channels selected from the family of PIEZO-1 and PIEZO-2 ion channels.

Abstract: The present invention relates to a neural implant comprising a biomaterial having an outer surface with a stochastic nanoroughness (Rq), and the application of said stochastic nanoroughness in the diagnosis and/or treatment of a neurological disorder, such as, for example, Parkinson's disease, Alzheimer's disease, glioblastoma and/or for disrupting, and/or preventing glial scars in the context of mammalian mechanosensing ion channels selected from the family of PIEZO-1 and PIEZO-2 ion channels.

Abstract: Devices associated with on-body analyte sensor units are disclosed. These devices include any of packaging and/or loading systems, applicators and elements of the on-body sensor units themselves. Also, various approaches to connecting electrochemical analyte sensors to and/or within associated on-body analyte sensor units are disclosed. The connector approaches variously involve the use of unique sensor and ancillary element arrangements to facilitate assembly of separate electronics assemblies and sensor elements that are kept apart until the end user brings them together.

Abstract: Disclosed is an electronic device including a plurality of electrodes selectively connectable to a touch sensor or one or more biometric sensors; and a processor configured to receive a user input through the plurality of electrodes in a state in which the touch sensor and the plurality of electrodes are connected; perform an operation relating to the touch sensor when where the user input satisfies a first condition; connect the plurality of electrodes to the one or more biometric sensors when where the user input satisfies a second condition; and obtain a plurality of pieces of biometric information according to a pre-determined sequence through the plurality of electrodes connected with the one or more biometric sensors.

Abstract: The disclosed human computer interface (HCI) system may include (1) at least one processor, (2) a plurality of sensors that detect one or more neuromuscular signals from a forearm or wrist of a user, and (3) memory that stores (A) one or more trained inferential models that determine an amount of force associated with the one or more neuromuscular signals and (B) computer-executable instructions that, when executed by the at least one processor, cause the at least one processor to (I) identify the amount of force determined by the one or more trained inferential models, (II) determine that the amount of force satisfies a threshold force value, and in accordance with the determination that the amount of force satisfies the threshold force value, (III) generate a first input command for the HCI system. Various other devices, systems, and methods are also disclosed.

Abstract: A method for creating a mother wavelet function. The method includes preparing a plurality of vectors, extracting a kernel from the plurality of vectors, and extracting the mother wavelet function from the kernel. The kernel includes a mode value of a vector of the plurality of vectors.

Abstract: A swallowing sensor that is attached to a person's pharyngeal portion and that measures the person's swallowing ability includes: a film-shaped detector that detects vibration based on displacement and sound of the pharyngeal portion; an adhesive layer that is provided on one of two main sides of the detector and that attaches the detector to the pharyngeal portion; and a sensing film arranged on the detector to cover entirety of the other main side of the detector, wherein a main side of the sensing film that contacts the detector contains an adhesive component, the sensing film is attachable to the pharyngeal portion around the detector using the adhesive component, and the sensing film conveys vibration to the detector. Accordingly, the swallowing ability can be more accurately measured.

Abstract: An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

Abstract: A device of and a method for obtaining thermal images of a living mammal body section. The device comprises a thermal energy storage surface structure for contacting the body section. In a calibration mode of operation, the thermal energy storage surface structure is brought at a reference temperature by transferring thermal energy to the thermal energy storage surface structure from a thermal energy transfer module that is controlled by a control circuit for restraining thermal energy transfer by the thermal energy transfer module in the presence of the body section at the thermal energy storage surface structure. In a registration mode of operation, by a thermal sensor, thermal images reflecting thermal energy storage over at least a portion of the thermal energy storage surface structure are obtained, with the body section contacting the thermal energy storage surface structure.

Abstract: A monitor recorder optimized for electrocardiography and respiratory data acquisition and processing is provided.

Abstract: A sensor can be manufactured by printing a working electrode onto a substrate using aerosol jet printing. Sensing chemistry (e.g., enzyme-based ink that including detection chemistry) also can be printed onto the working electrode using aerosol jet printing. A reference electrode also can be printed on the substrate at a position spaced along the substrate from the working electrode. In certain examples, the substrate can be positioned within a lumen of a skin piercing member of a sensor module.

Abstract: Aspects of the present disclosure relate to electrophysiology catheters for cardiac medical procedures. More specifically, the instant disclosure relates to an ablation catheter for treating cardiac arrhythmias by ablating tissue, and having one or more subelectrodes internally fixed within the ablation catheter tip to capture electrophysiology characteristics of myocardial tissue in proximity to the one or more subelectrodes.

Abstract: An extended wear electrocardiography and physiological sensor monitor is provided. An electrode patch includes an integrated flexible circuit having a single piece of material that includes a longitudinal midsection between upper and lower ends and a mirror image shape of the upper end extending from at least a portion of one side of the upper end that runs substantially parallel to the midsection and folds over the upper end. A receptacle is adhered on an outward surface of the mirror image when the integrated circuit is folded over the upper end. One electrode is positioned on a contact surface of the integrated circuit on the upper end and another electrode is positioned on the contact surface on the lower end. A battery is directly adhered to the outward surface of the mirror image and positioned under the receptacle. A monitor is configured to be removably secured in the receptacle.