Abstract: An implantable penile prosthesis is attachable to a pump and a reservoir and includes a distal part formed by a rear tip that is connected to a proximal part formed by a cylinder. The cylinder is oriented on a first longitudinal axis, and a distal portion of the rear tip forms a fluid chamber communicating with the cylinder. A tubing junction is integrally formed with the distal portion and communicates with the fluid chamber in the rear tip. A strain relief portion has a bore disposed on a second longitudinal axis, where the second longitudinal axis forms an acute angle relative to the first longitudinal axis, and the acute angle has a measurement that does not exceed 5 degrees. An exterior surface of the rear tip, between the tubing junction and the cylinder, provides the distal portion of the rear tip with a constant outer diameter.

Abstract: An empty reservoir empty of liquid is useful with an implantable penile prosthetic. The empty reservoir includes a first major surface separated from a second major surface by a side wall. The first major surface and the second major surface each include a depression having a complex concave curvature with a lateral concave curvature formed between opposed sides of the side wall and a longitudinal concave curvature formed between an end and a neck of the empty reservoir.

Abstract: One aspect of the present disclosure relates to an implantable penile prosthesis including an elongated cylinder that includes a pendulous portion configured to move from a non-pressurized state to a pressurized state. A tapered tailoring portion of the elongated cylinder is configured to anchor the elongated cylinder at a base of the penis. The elongated cylinder further includes a flared reservoir portion, at least a portion of which has a diameter that is greater than a diameter of the pendulous portion.

Abstract: A pump adapted to be attached between a fluid reservoir and an inflatable penile cylinder of an inflatable penile prosthesis includes a pump bulb connected to a pump body. The pump body includes a deflate valve chamber communicating with an actuator chamber, a deflate cap attached to the deflate valve chamber, and the actuator chamber including a restriction ring. An inlet valve is disposed within the pump body between the pump bulb and the deflate valve chamber. An exhaust valve is disposed within the pump body between the pump bulb and the actuator chamber. A deflate valve is disposed within the pump body between the inlet valve and the exhaust valve. The restriction ring in the actuator chamber is sized to engage a ring engagement surface of the deflate valve to maintain the deflate valve in the deflate mode.

Abstract: A penile prosthetic system includes a pump connected between a reservoir and an inflatable penile implant. The inflatable penile implant includes a cylinder and a distal end portion connected to a distal end of the cylinder along a major longitudinal axis of the cylinder. The distal end portion forms a fluid chamber that is in fluid communication with the cylinder, and a fluid conduit is integrally formed to communicate with the fluid chamber in the distal end portion. The fluid conduit has a minor longitudinal axis that forms an angle with the major longitudinal axis of 5 degrees or less.

Abstract: A male sexual impotence treatment apparatus comprises an adjustable non-inflatable restriction device implanted in a male impotent patient. The restriction device directly engages a portion of the normal penile tissue of the patient, such as both of the corpora cavernosa as a single unit or one or more of the exit veins from the penis, to affect the blood flow leaving the penis. An adjustment device mechanically adjusts the restriction device to temporarily restrict the blood flow leaving the penis when the patient wishes to achieve erection.

Abstract: A surgical method of treating erectile dysfunction includes implanting a penile prosthetic in a patient. The penile prosthetic includes an inflatable portion implantable into a penis that is attachable to a liquid reservoir, a pump, and a deflation assembly. The method includes implanting the deflation assembly in contact with an exterior surface of a pelvis of the patient, and positioning an activation surface of the deflation assembly away from the exterior surface of the pelvis. The method thus allows the patient to palpate the activation surface through skin.

Abstract: An implantable penile prosthetic includes a pump attachable between a body implantable reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The body implantable reservoir is substantially empty of liquid prior to implantation and includes a first end portion including a neck having an opening that is adapted to communicate with the pump and an end wall on an end of the reservoir that is opposite of the neck. The end wall extends between a first surface of the reservoir and a second surface of the reservoir. The reservoir includes a first substantially planar edge surrounding a periphery of the first surface of the reservoir and a second substantially planar edge surrounding a periphery of the second surface of the reservoir. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge.

Abstract: An implantable medical device includes an inflatable member, a reservoir, a pump attachable between the inflatable member and the reservoir and operable to move fluid from the reservoir to inflate the inflatable member, and a deflation assembly attachable between the pump and the reservoir. The deflation assembly includes a valve that selectively restricts movement of the fluid from the inflatable member to the reservoir, a base and an activation surface opposite the base. The activation surface has an outer peripheral rim surrounding a pad that is movable to displace the valve to allow the fluid to flow from the inflatable member to the reservoir. The pad is recessed relative to the outer peripheral rim such that the outer peripheral rim defines a maxima of the activation surface.

Abstract: An implant for helping a male patient achieve a penile erection, the implant comprising a pair of substantially straight and substantially rigid rods and an interconnecting structure. The rods are configured for being implanted subcutaneously in the patient and are selectively movable from a retracted mode of the implant to a deployed mode of the implant, where in the deployed mode a desired portion of each rod is within the penis shaft and in the retracted mode at least a majority of each rod is out of the penis shaft. Each rod comprises at least one flexible portion, the flexible portion being configured for being bent at a desired angle and for maintaining the desired angle. The interconnecting structure is implanted subcutaneously in the patient and joined to the rods, and is configured for stabilizing the rods within the penis shaft.

Abstract: The present invention generally relates to methods, compositions and uses thereof for enhancing vascularization of a tissue or cell transplant for transplantation into a subject. In particular, one aspect of the present invention provides methods and compositions comprising the use of a population of stromal vascular fraction (SVF) cells to encapsulate or surround a tissue or cell transplant to enhance vascularization of the tissue or cell transplant. Another aspect of the present invention provides methods and compositions for enhancing vascularization of a tissue or cell transplant by combining a population of SVF cells with a tissue or cell transplant to form a transplant mixed with SVF cells.

Abstract: A delivery tool and related methods for transporting a pre-assembled implantable penile prosthesis to an operating room. The delivery tool includes at least a first cap with receptacles for receiving and retaining pre-connected components during transport to prevent shifting, tangling and/or damage to the pre-connected components. The receptacles can be adapted for receiving pre-connected components, tubing used to connect the components, as well as stand-alone components that are utilized during a surgical procedure. The delivery tool can include cushioning elements for protecting the pre-connected components from damage caused by shifting during transport.

Abstract: A penile prosthetic system includes a reservoir that is configured to be attached to a penile implant. The penile implant includes a first bladder and a second bladder, with the first bladed configured to be attached into fluid communication with the reservoir and the second bladder containing a dilatant liquid.

Abstract: A method of implanting a medical device includes implanting a cylinder into a corpora cavernosum of a patient, and coupling the cylinder to a reservoir, a pump, and a deflation assembly. The deflation assembly is separate from the reservoir and separate from the pump. The method additionally includes implanting the deflation assembly between transversalis fascia and an exterior surface of a pelvis of the patient.

Abstract: A male impotence prosthesis apparatus comprises an operable penile prosthesis (4) implanted in an impotent patient's corpus cavernosum to provide flaccid or erect states of the patient's penis. An energy transmission device (10) for wireless transmission of energy from outside the patient's body to inside the patient's body is provided for use in connection with the operation of the penile prosthesis.

Abstract: A medical implant system for implantation in a patient to treat erectile dysfunction includes a first fluid path, an inflatable penile prosthesis cylinder, an electric pump, and implant controller, and an implantable power supply. The inflatable penile prosthesis cylinder is in fluid communication with the first fluid path and is configured for implantation in a corpus cavernosum of a patient. The electric pump is in fluid communication with the first fluid path. The implant controller is electrically coupled to the pump and is configured to activate the pump to drive a flow of fluid through the first fluid path and into the cylinder. The implantable power supply provides electrical power to the pump.

Abstract: A method of implanting a penile prosthetic in a man includes providing a reservoir having a first major surface separated from to a second major surface by a side wall, the first major surface and the second major surface are both concave and form opposed depressions in the reservoir when the reservoir is empty of liquid. The method additionally includes connecting the reservoir to a pump that is connected to a cylinder, implanting the pump in the scrotum, implanting the cylinder in a corpora cavernosum of the penis, and implanting the reservoir in the man.

Abstract: The present invention relates to an erection assistance device that includes: an elastic penis implant which has a semi-cylindrical shape, with its lower pan opened, and is processed to be inserted between an epidermis and a cavernous body of a penis; a storing part which is connected to the expansive part via connection pipes and stores a fluid to be supplied into the expansive part; and a pump which is provided in the middle of the connection pipes, wherein the pump is manipulated to adjust a degree of expansion of the penis implant.

Abstract: A penile prosthesis implantation device comprises a barrel, an obturator and a needle clamp. The obturator includes a distal end that is received within the bore and is configured to slide along a longitudinal axis of the bore relative to the barrel. The needle clamp at the distal end of the obturator includes opposing pinching surfaces that are displaced from an interior wall of the bore, and a receptacle between the pinching surfaces configured to receive a thread attachment end of a needle and hold the end of the needle through an interference fit with the pinching surfaces.

Abstract: A method of treating erectile dysfunction includes providing a pump having a proximal tip communicating with a fluid reservoir, a bladder connected at a proximal end to the proximal tip and extending to a closed distal end, and a tube disposed in the bladder, the tube having a proximal end in fluid communication with the fluid reservoir and a distal end that opens into the bladder. The method additionally includes implanting the pump into a corpora cavernosum of a penis.

Abstract: A penile prosthetic assembly includes a penile implant containing a dilatant liquid and a reservoir connectable with the penile implant. Fluid transferred from the reservoir into the penile implant imposes a shear on the dilatant liquid to increase viscosity in the dilatant liquid and harden the penile implant.

Abstract: A pump that comprises a fluid reservoir, a pump bulb, a plurality of tubing, and at least one inflatable penile cylinder. The pump comprises a pump body, an inlet valve within the pump body, an exhaust valve within the pump body and in fluid communication with the inlet valve, and a deflate valve within the pump body and in fluid communication with the inlet valve and the exhaust valve. The deflate valve enables one-touch release by (i) providing a voluntarily-activated fluid bypass so that fluid from the at least one inflatable penile cylinder can return to the fluid reservoir through at least one of the plurality of tubing without sustained activation of the deflate valve, and (ii) closing upon subsequent inflation of the at least one inflatable penile cylinder when such inflation is initiated by squeezing the pump bulb so that fluid does not flow back to the fluid reservoir.

Abstract: A body implantable penile prosthetic assembly offering a user a one touch to erection (OTTER) capability and a penile implant deflation capability is described. The assembly includes a pump and a release mechanism. The pump is connectable to a pressure reservoir and a penile implant. The pump is operable to pressurize liquid in the pressure reservoir and the pressure reservoir is operable to store the pressurized liquid at a first pressure between 20-50 PSIg that is configured to inflate the penile implant to an erect state. The release mechanism is connectable between the pressure reservoir and the penile implant. The release mechanism is operable to inflate the penile implant with one-touch input from the user where the release mechanism is configured to release the stored pressurized liquid from the pressure reservoir to inflate the penile implant at a second pressure between 10-20 PSIg.

Abstract: A pump connected to a reservoir and a cylinder of an implantable penile prosthesis includes a pump body and an inlet valve assembly. The pump body has a pump bulb connected to the pump body, where the pump bulb is operable to move fluid between the reservoir and the cylinder. The inlet valve assembly includes a valve and a tubular sleeve that provides an exit valve seat. The inlet valve assembly is disposed in an inlet channel of the pump body and operable to allow a portion of fluid to be drawn from the reservoir through the tubular sleeve and through the inlet channel to the pump bulb for delivery into the cylinder.

Abstract: A male sexual impotence treatment apparatus comprises an adjustable non-inflatable restriction device (434) implanted in a male impotent patient. The restriction device directly engages a portion of the normal penile tissue of the patient, such as both of the corpora cavernosa as a single unit or one or more of the exit veins from the penis, to affect the blood flow leaving the penis. An adjustment device (436) mechanically adjusts the restriction device to temporarily restrict the blood flow leaving the penis when the patient wishes to achieve erection.

Abstract: A penile prosthesis includes an inflatable cylinder and a pump. The inflatable cylinder includes an inflatable volume extending within a front tip, a reservoir within a rear tip, and a deflation block. The deflation block is positioned between the inflatable volume and the reservoir, and includes a one-way valve configured to control a flow of fluid from the inflatable volume to the reservoir. The pump is configured to drive fluid from the reservoir and into the inflatable volume.

Abstract: An implantable penile prosthetic includes a pump attachable between a body implantable reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The body implantable reservoir is substantially empty of liquid prior to implantation and includes a first end portion including a neck having an opening that is adapted to communicate with the pump and an end wall on an end of the reservoir that is opposite of the neck. The end wall extends between a first surface of the reservoir and a second surface of the reservoir. The reservoir includes a first substantially planar edge surrounding a periphery of the first surface of the reservoir and a second substantially planar edge surrounding a periphery of the second surface of the reservoir. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge.

Abstract: A penile prosthetic includes a proximal tip in communication with a reservoir, a cylinder bladder connected at a proximal end to the proximal tip and extending to a distal end, and peristaltic tubing disposed inside the cylinder bladder. The peristaltic tubing has a proximal end that communicates with the reservoir and a distal end that is open to the cylinder bladder. Peristaltic compression applied from the proximal end to the distal end of the peristaltic tubing pumps fluid from the reservoir into the cylinder bladder.

Abstract: A body implantable penile prosthetic assembly includes a pump and a release mechanism. The pump is connectable to a pressure reservoir and a penile implant, where the pressure reservoir contains a pressurized liquid at a first pressure when implanted. The release mechanism is connectable between the pressure reservoir and the penile implant and is configured to release the pressurized liquid from the pressure reservoir to inflate the penile implant to a second pressure that is less than the first pressure. The pump is operable to transfer the pressurized liquid from the penile implant to the pressure reservoir to deflate the penile implant, and pressurize the pressurized liquid in the pressure reservoir from the second pressure to at least the first pressure.

Abstract: An implantable medical device includes an inflatable member, a reservoir, a pump attachable between the inflatable member and the reservoir and operable to move fluid from the reservoir to inflate the inflatable member, and a deflation assembly attachable between the pump and the reservoir. The deflation assembly includes a valve that selectively restricts movement of the fluid from the inflatable member to the reservoir, a base and an activation surface opposite the base. The activation surface has an outer peripheral rim surrounding a pad that is movable to displace the valve to allow the fluid to flow from the inflatable member to the reservoir. The pad is recessed relative to the outer peripheral rim such that the outer peripheral rim defines a maxima of the activation surface.

Abstract: An artificial urinary sphincter system includes a cuff implantable around a portion of a urethra, an implantable pressure-regulating reservoir, and a deflation assembly attachable between the cuff and the implantable pressure-regulating reservoir. The deflation assembly includes a valve that selectively restricts movement of the fluid from the cuff to the pressure-regulating reservoir, a base and an activation surface opposite the base. The activation surface includes an outer peripheral rim surrounding a pad that is movable to displace the valve to allow the fluid to flow from the cuff to the pressure-regulating reservoir. An entirety of the pad is recessed relative to the outer peripheral rim such that the outer peripheral rim defines a maxima of the activation surface.

Abstract: A method of providing a user with a body implantable penile prosthetic includes providing a pump attachable to a pressure reservoir and a penile implant; pressurizing liquid in the pressure reservoir; configuring the pressure reservoir to release the pressurized liquid from the pressure reservoir to the penile implant at a first pressure for inflating the penile implant to an erect state; and pumping the pressurized liquid from the penile implant to the pressure reservoir and pressurizing the pressurized liquid to a second pressure greater than the first pressure.

Abstract: A dual poppet valve assembly for a pump assembly of an implantable penile prosthesis having a suction poppet engagable by a plurality of fingers allowing free travel of the poppet and to prevent vacuum lockup of the pump assembly. The suction poppet can also include an elongated shaft receivable within a corresponding bore of a cylinder poppet to prevent the suction poppet from becoming misaligned during the operation of the pump assembly.

Abstract: A device configured for being implanted in a male patient's body for assisting the patient to achieve an erection. The device includes at least two rods and an interconnecting structure. The rods can be selectively deployed to the penis shaft when an erection is to be achieved and retracted away from the penis shaft when the patient does not need to achieve an erection. The interconnecting structure is joined to the rods and is configured to stabilize the rods while the rods are in the penis shaft.

Abstract: An implantable penile prosthetic includes a pump attachable between a reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The reservoir has a central longitudinal axis and includes a wall connected between a first edge of a first surface and a second edge of a second surface. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge such that each of the first and second surfaces form a depression in the reservoir when the reservoir is empty of liquid. The reservoir expands to contain liquid such that the first surface and the second surface are both convex relative to the central longitudinal axis.

Abstract: An implantable penile prosthetic includes a pump attachable between a reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The reservoir has a central longitudinal axis and includes a wall connected between a first edge of a first surface and a second edge of a second surface. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge such that each of the first and second surfaces form a depression in the reservoir when the reservoir is empty of liquid. The reservoir expands to contain liquid such that the first surface and the second surface are both convex relative to the central longitudinal axis.

Abstract: A male chastity apparatus, system and method are disclosed. The apparatus, in one embodiment, includes a housing, a protrusion, and a lock. The housing is configured to contain a shaft of a penis of a user. The housing, in certain embodiments, is made of a substantially rigid material that prevents the user from stimulating the shaft of the user's penis. The protrusion is configured to engage a piercing in the user's penis. The protrusion, in certain embodiments, is also made of a substantially rigid material. The lock is configured to engage the protrusion and to attach the protrusion to the housing.

Abstract: An implantable penile prosthesis having an inflatable cylinder with at least one piezoelectric pump for transferring fluid between an integrated reservoir and pressure chamber within the inflatable cylinder. The piezoelectric pump includes an actuator powered by an inductor coil integrated into the inflatable cylinder allowing for wireless control of the inflation and deflation of the inflatable cylinder. An external control system having a corresponding inductive coil can be used to supply a magnetic field for creating a current in the inductor coil integrated into the inflatable cylinder.

Abstract: A penile prosthetic includes a cylinder, a reservoir, a pump, and a deflation assembly. The cylinder is implantable in a corpora cavernosum. The pump is attachable between the cylinder and the reservoir and is operable to move fluid from the reservoir to inflate the cylinder. The deflation assembly is attachable between the pump and the reservoir and includes a valve that selectively restricts movement of the fluid from the cylinder to the reservoir, a base and an activation surface opposite the base, where the activation surface includes an outer peripheral rim surrounding a pad that is movable to displace the valve to allow the fluid to flow from the cylinder to the reservoir. An entirety of the pad is recessed relative to the outer peripheral rim such that the outer peripheral rim defines a maxima of the activation surface.

Abstract: A penile prosthesis is disclosed that can alternate between an erect and flaccid state based on the shape memory properties of an exoskeleton that is responsive to increases and decreases in temperature. The exoskeleton consists of a shape memory alloy, such as nitinol, which in the erect configuration can radially expand and resist axial loads and buckling forces during coitus. The shape memory alloy is temperature-tuned to undergo a change to an erect state under external application of heat and can revert to a flaccid state with cooling below resting penile temperature.

Abstract: A method treating erectile dysfunction includes implanting a penile implant including a first bladder and a second bladder, the second bladder filled with a liquid having a rest viscosity. The method additionally includes increasing a pressure in the first bladder of the penile implant from a first pressure to a second pressure, and increasing a viscosity in the liquid from the rest viscosity to a second viscosity greater than the rest viscosity. The method further includes maintaining the first bladder of the penile implant at the second pressure and the liquid in the second bladder at the second viscosity.

Abstract: A penile prosthetic includes a proximal tip in communication with a reservoir, a cylinder bladder connected at a proximal end to the proximal tip and extending to a distal end, and peristaltic tubing disposed inside the cylinder bladder. The peristaltic tubing has a proximal end that communicates with the reservoir and a distal end that is open to the cylinder bladder. Peristaltic compression applied from the proximal end to the distal end of the peristaltic tubing pumps fluid from the reservoir into the cylinder bladder.

Abstract: According to various embodiments, an IPP includes unbiased one-way check valve assemblies either independently or in conjunction with other valve assemblies to direct fluid into and evacuate fluid out of inflatable penile cylinders. The fluid transfer system transfers fluid from the fluid reservoir to inflatable penile cylinders and includes a fluid transfer bulb, unbiased inlet valve assembly, unbiased exhaust valve assembly and spool valve assembly. The cylinder deflate mechanism evacuates fluid from the penile cylinders to the reservoir and includes a deflate actuator, unbiased return valve assembly, and spool valve assembly.

Abstract: Disclosed is a method of augmenting the glans that can safely and naturally expand the glans without causing problems such as an unnatural rough or shiny surface of the glans and the severe side effects of epidermal necrosis, which are caused by the conventional method of augmenting the glans. The method includes inserting an injector needle for injecting a filler into the central area of the lamina propria through the peripheral area of the ostium urethrae externum of the glans, slowly injecting the filler while checking with visual and tactual senses that the glans tissue where the filler is injected swells up and becomes tight and pressure resistance occurs and is maintained during injection of the filler, and slowly injecting the filler whereby the filler is uniformly spread by changing the depth and the direction of the inserted injector needle to expand half the glans area with a one-time injection.

Abstract: A method of implanting a penile prosthetic in a man includes providing a reservoir having a first major surface separated from to a second major surface by a side wall, the first major surface and the second major surface are both concave and form opposed depressions in the reservoir when the reservoir is empty of liquid. The method additionally includes connecting the reservoir to a pump that is connected to a cylinder, implanting the pump in the scrotum, implanting the cylinder in a corpora cavernosum of the penis, and implanting the reservoir in the man.

Abstract: An implantable penile prosthetic includes a pump attachable between a reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The reservoir has a central longitudinal axis and includes a wall connected between a first edge of a first surface and a second edge of a second surface. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge such that each of the first and second surfaces form a depression in the reservoir when the reservoir is empty of liquid. The reservoir expands to contain liquid such that the first surface and the second surface are both convex relative to the central longitudinal axis.

Abstract: An implantable penile prosthetic includes a pump attachable between a reservoir and a cylinder that is implantable into a corpora cavernosum of a penis. The reservoir has a central longitudinal axis and includes a wall connected between a first edge of a first surface and a second edge of a second surface. The first surface is concave relative to the first edge and the second surface is concave relative to the second edge such that each of the first and second surfaces form a depression in the reservoir when the reservoir is empty of liquid. The reservoir expands to contain liquid such that the first surface and the second surface are both convex relative to the central longitudinal axis.

Abstract: An implantable system for erectile dysfunction treatment includes an implantable pump having an inlet and an outlet port. The inlet port is configured to receive blood from an artery within the body. The outlet port is configured to receive the blood from the inlet port and deliver that blood to an artery having a direct or indirect path to the corpora cavernosa of the penis. Activation of the pump, preferably via manual compression or electrical activation, causes the transfer of blood and ultimately an erection. Upon conclusion of sexual activity, blood drains from the penis in a normal manner and returns the penis to a flaccid state. The pump preferably incorporates a non-return valve to prevent backflow of blood from outlet port to inlet port.

Abstract: A method of implanting a medical device includes implanting a cylinder into a corpora cavernosum of a patient, and coupling the cylinder to a reservoir, a pump, and a deflation assembly. The deflation assembly is separate from the reservoir and separate from the pump. The method additionally includes implanting the deflation assembly between transversalis fascia and an exterior surface of a pelvis of the patient.

Abstract: A penile prosthetic includes a cylinder, a reservoir, a pump, and a deflation assembly. The cylinder is implantable in a corpora cavernosum. The pump is attachable between the cylinder and the reservoir and is operable to move fluid from the reservoir to inflate the cylinder. The deflation assembly is attachable between the pump and the reservoir and includes a valve that selectively restricts movement of the fluid from the cylinder to the reservoir, a base and an activation surface opposite the base, where the activation surface includes an outer peripheral rim surrounding a pad that is movable to displace the valve to allow the fluid to flow from the cylinder to the reservoir. An entirety of the pad is recessed relative to the outer peripheral rim such that the outer peripheral rim defines a maxima of the activation surface.