Abstract: A penile implant includes an inflatable bladder providing a fluid chamber, a distal tip extending from a distal end of the inflatable bladder, and a proximal tip assembly extending from a proximal end of the inflatable bladder. The proximal tip assembly includes a tip core providing a first proximal tip diameter and a tip sleeve disposed over the tip core to provide a second proximal tip diameter that is larger than the first proximal tip diameter. The tip sleeve is removable from the tip core to provide the penile implant with a proximal tip that is convertible between the first and second proximal tip diameters.

Abstract: A penile prosthetic includes a proximal tip in communication with a reservoir, a cylinder bladder connected at a proximal end to the proximal tip and extending to a distal end, and peristaltic tubing disposed inside the cylinder bladder. The peristaltic tubing has a proximal end that communicates with the reservoir and a distal end that is open to the cylinder bladder. Peristaltic compression applied from the proximal end to the distal end of the peristaltic tubing pumps fluid from the reservoir into the cylinder bladder.

Abstract: A pump connected to a body implantable penile prosthesis including a reservoir maintaining a fluid volume that is transferrable into a cylinder of the penile prosthesis is described. The pump includes a pump bulb connected to a pump body that is in fluid communication with the reservoir and the cylinder; an inlet valve operable to allow a portion of the fluid volume to be drawn from the reservoir and delivered into the pump bulb; an exhaust valve operable to allow the portion of the fluid volume delivered into the pump bulb to be pumped into the cylinder; and an anti-autoinflation (AAI) valve disposed in the pump body and comprising a seal that is biased to prevent fluid flow from bypassing the pump bulb and flowing from the reservoir to the cylinder.

Abstract: A pump connected to a reservoir and a cylinder of an implantable penile prosthesis includes a pump body and an inlet valve assembly. The pump body has a pump bulb connected to the pump body, where the pump bulb is operable to move fluid between the reservoir and the cylinder. The inlet valve assembly includes a valve and a tubular sleeve that provides an exit valve seat. The inlet valve assembly is disposed in an inlet channel of the pump body and operable to allow a portion of fluid to be drawn from the reservoir through the tubular sleeve and through the inlet channel to the pump bulb for delivery into the cylinder.

Abstract: A male sexual impotence treatment apparatus includes or use an operable restriction device implantable in a male patient for engaging a tissue portion of the penile tissue to form a restrictable passageway for the penile exit blood flow. An energy transmission device is provided for wireless transmission of energy from outside the patient's body to inside the patient's body for use in connection with the operation of the restriction device, including temporarily contracting said tissue portion to restrict the penile exit blood flow in the blood flow passageway to achieve erection.

Abstract: A pump includes a pump body and a pump bulb that is connected to the pump body, an inlet valve assembly, and an exhaust valve assembly. The pump bulb is operable to move fluid between the reservoir and the cylinder. The inlet valve assembly includes a valve and a tubular sleeve that provides an exit valve seat. The inlet valve assembly is operable to allow a portion of fluid to be drawn from the reservoir through the tubular sleeve and through the inlet channel for delivery into the pump bulb. The exhaust valve assembly is operable to allow the portion of the fluid delivered into the pump bulb to be moved into the cylinder. The valve is movable to contact the exit valve seat and prevent fluid that is flowing from the cylinder to the reservoir from flowing through the inlet channel.

Abstract: According to various embodiments, an inflatable penile prosthesis (IPP) includes a rigidly constructed spool valve assembly that is used to direct fluid into and evacuate fluid out of the inflatable penile cylinders. The fluid transfer system transfers fluid from the fluid reservoir to the inflatable penile cylinders and includes the fluid transfer bulb, inlet valve, exhaust valve and spool valve assembly. The cylinder deflate mechanism evacuates fluid from the penile cylinders to the reservoir and includes the deflate actuator, return valve and spool valve assembly.

Abstract: A method of implanting a penile prosthesis into a patient includes inserting a distal end of an insertion tool into an opening formed in a tip of the penile prosthesis, expanding a mechanism from the distal end of the insertion tool into a pocket formed in the tip of the penile prosthesis, and inserting the penile prosthesis into a corpora cavernosum of the patient with the insertion tool.

Abstract: A method treating erectile dysfunction includes implanting a penile implant including a first bladder and a second bladder, the second bladder filled with a liquid having a rest viscosity. The method additionally includes increasing a pressure in the first bladder of the penile implant from a first pressure to a second pressure, and increasing a viscosity in the liquid from the rest viscosity to a second viscosity greater than the rest viscosity. The method further includes maintaining the first bladder of the penile implant at the second pressure and the liquid in the second bladder at the second viscosity.

Abstract: A penile prosthetic assembly includes a penile implant containing a dilatant liquid and a reservoir connectable with the penile implant.

Abstract: A Peyronie's treatment device is described that is configured to treat an erect penis having curvature characterized by a first penis side with an unaffected length and a second penis side with an affected length that is shorter than the unaffected length. The device includes a band connected between a proximal support that is attachable to a base of a penis and a distal support that is attachable adjacent a corona of the penis. The band has an elastic material and a second material that is attached to the elastic material. The second material is provided to stop elongation of the elastic material at a length approximately equal to the affected length of the erect penis.

Abstract: An implantable penile prosthesis having an adjustable length rear tip extender. The extender is connectable with at least one inflatable cylinder. The adjustable length rear tip extender can be telescoping, or include one or more segments capable of being cut away or otherwise removed, to adjust the effective length for the at least one inflatable cylinder.

Abstract: A system and related method for treating ED in a patient is provided. The system can include a small cuff or other selective restriction mechanism or device implanted at or along the existing veins of the penis to control blood flow out of the penis. As such, the system can utilize blood pressure from the heart to achieve and maintain an erection by restricting blood flow out of the penis.

Abstract: A traction ring for use in a penile implant procedure can include a plurality of elastic sutures. Each elastic suture can have an elastic body with an attachment loop at one end and an adhesive pad at the opposed end. The attachment loop allows for positioning of the elastic suture at any of a plurality of available attachment grooves located about a perimeter of the traction ring. The adhesive pad is generally attached to penis proximate the penis tip. Adhesive pad can be bonded to the penis with a suitable skin adhesive. The skin adhesive can be contained within a reservoir on the adhesive pad. Alternatively, the adhesive pad can be separated from the elastic body. A removal solvent can be applied to dissolve or otherwise break down the skin adhesive following completion of an implant procedure.

Abstract: An instrument configured to prepare a penis for implantation of a penile prosthetic includes a shaft extending between a distal end and a proximal end, a plunger coupled to and movable relative to the shaft, and a dilation head coupled to a distal end of the plunger and disposed around an exterior of the shaft. The dilation head is movable longitudinally along the shaft.

Abstract: A Peyronie's treatment device is described that is configured to treat an erect penis having curvature characterized by a first penis side with an unaffected length and a second penis side with an affected length that is shorter than the unaffected length. The device includes a band connected between a proximal support that is attachable to a base of a penis and a distal support that is attachable adjacent a corona of the penis. The band has an elastic material and a second material that is attached to the elastic material. The second material is provided to stop elongation of the elastic material at a length approximately equal to the affected length of the erect penis.

Abstract: A pump that comprises a fluid reservoir, a pump bulb, a plurality of tubing, and at least one inflatable penile cylinder. The pump comprises a pump body, an inlet valve within the pump body, an exhaust valve within the pump body and in fluid communication with the inlet valve, and a deflate valve within the pump body and in fluid communication with the inlet valve and the exhaust valve. The deflate valve enables one-touch release by (i) providing a voluntarily-activated fluid bypass so that fluid from the at least one inflatable penile cylinder can return to the fluid reservoir through at least one of the plurality of tubing without sustained activation of the deflate valve, and (ii) closing upon subsequent inflation of the at least one inflatable penile cylinder when such inflation is initiated by squeezing the pump bulb so that fluid does not flow back to the fluid reservoir.

Abstract: A pump that comprises a fluid reservoir, a pump bulb, a plurality of tubing, and at least one inflatable penile cylinder. The pump comprises a pump body, an inlet valve within the pump body, an exhaust valve within the pump body and in fluid communication with the inlet valve, and a deflate valve within the pump body and in fluid communication with the inlet valve and the exhaust valve. The deflate valve enables one-touch release by (i) providing a voluntarily-activated fluid bypass so that fluid from the at least one inflatable penile cylinder can return to the fluid reservoir through at least one of the plurality of tubing without sustained activation of the deflate valve, and (ii) closing upon subsequent inflation of the at least one inflatable penile cylinder when such inflation is initiated by squeezing the pump bulb so that fluid does not flow back to the fluid reservoir.

Abstract: A body implantable penile prosthetic assembly includes a penile implant and a reservoir. The penile implant includes a first bladder and a second bladder, where the second bladder contains a dilatant liquid. The reservoir is connectable with the first bladder of the penile implant. In this regard, fluid transferred from the reservoir into the first bladder of the penile implant imposes a shear on the dilatant liquid in the second bladder of the penile implant to increase viscosity in the dilatant liquid and harden the penile implant.

Abstract: A penis erection stimulation system comprises a fully implantable drug delivery device for delivering a drug in relation to a penis to achieve erection of the penis. The drug delivery device may comprise a catheter adapted to be implanted in the corpora cavernosa of a penis or in close proximity thereto in order to deliver drugs through said catheter. Alternatively, one or more infusion needles may be disposed within and implanted along with one or more housings adjacent the patient's left and right corpora cavernosa. A reservoir and a pump may also be implanted inside the patient's body to supply the infusion needle with infusion liquid.

Abstract: A body implantable penile prosthetic assembly includes a pump and a release mechanism. The pump is connectable to a pressure reservoir and a penile implant, where the pressure reservoir contains a pressurized liquid at a first pressure when implanted. The release mechanism is connectable between the pressure reservoir and the penile implant and is configured to release the pressurized liquid from the pressure reservoir to inflate the penile implant to a second pressure that is less than the first pressure. The pump is operable to transfer the pressurized liquid from the penile implant to the pressure reservoir to deflate the penile implant, and pressurize the pressurized liquid in the pressure reservoir from the second pressure to at least the first pressure.

Abstract: A penile implant includes an inflatable bladder providing a fluid chamber, a distal tip extending from a distal end of the inflatable bladder, and a proximal tip assembly extending from a proximal end of the inflatable bladder. The proximal tip assembly includes a tip core providing a first proximal tip diameter and a tip sleeve disposed over the tip core to provide a second proximal tip diameter that is larger than the first proximal tip diameter. The tip sleeve is removable from the tip core to provide the penile implant with a proximal tip that is convertible between the first and second proximal tip diameters.

Abstract: An inflatable penile prosthesis cylinder of the present invention includes an inflatable chamber and a constraining sleeve of fabric. The inflatable chamber is configured to expand in response to an increase in pressure within the chamber. The sleeve of fabric constrains the expansion of the chamber, however, the sleeve of fabric includes a corrugation that facilitates some expansion of the sleeve.

Abstract: A male sexual impotence prosthesis apparatus comprises an operable prosthesis implanted in the cavities of the corpora cavemosa of a patient's penile tissue for providing erect penile condition, when the prosthesis is operated. The prosthesis is operable by an implanted operation device. A control device is provided for controlling a source of energy, which may or may not be implanted, from outside the patient's body, to release energy for use in connection with the operation of the prosthesis, i.e., to power the operation device. The patient uses the control device to operate the prosthesis to achieve erection.

Abstract: An inflatable penile prosthesis of the present invention includes a cylinder that has an external wall that defines a pressure chamber. That external wall preferably incorporates a number of corrugations that extend in a longitudinal direction of the cylinder. In a preferred embodiment, the external wall of the cylinder is formed of a polyurethane or of a material having a modulus of elasticity greater than that of silicone. The corrugations enable the cylinder to move from a small, deflated diameter to a much greater diameter in the inflated state.

Abstract: An inflatable penile prosthesis includes an implantable pump having a bypass valve. The bypass valve includes a cavity having a valve seat at a port, a poppet and a spring. The poppet includes a valve member and a stem extending from the valve member. In operation, the poppet includes a sealing position, where the valve member seals the port through contact with the valve seat, and a deflating position, where the valve member is displaced from the valve seat. The spring is configured to bias the valve member toward the valve seat, wherein the spring engages a portion of the stem while the poppet is in the deflating position.

Abstract: Penile implant and system comprising such an implant. The penile implant comprises a number of features which improves the function of the penile implant, e.g. a certain surface structure and portions with specific functions.

Abstract: Penile implant and system comprising such an implant. The penile implant comprises a number of features which improves the function of the penile implant, e.g. a certain surface structure and portions with specific functions.

Abstract: A penile prosthetic includes a proximal tip in communication with a reservoir, a cylinder bladder connected at a proximal end to the proximal tip and extending to a distal end, and peristaltic tubing disposed inside the cylinder bladder. The peristaltic tubing has a proximal end that communicates with the reservoir and a distal end that is open to the cylinder bladder.

Abstract: A method of treating erectile dysfunction includes providing a pump having a proximal tip communicating with a fluid reservoir, a bladder connected at a proximal end to the proximal tip and extending to a closed distal end, and a tube disposed in the bladder, the tube having a proximal end in fluid communication with the fluid reservoir and a distal end that opens into the bladder. The method additionally includes implanting the pump into a corpora cavernosum of a penis.

Abstract: A cap configured to be attached to a cylinder of an implantable penile prosthesis includes a body section and a tip section. The body section defines a recess that is attachable to an end of the cylinder of the implantable penile prosthesis and the tip section terminates in a tip having a curved exterior surface. The tip section defines at least one slot formed therein that extends away from the body section and has a slot axis that intersects with a longitudinal axis of the cap.

Abstract: An implantable pump with a plurality of protrusions and grooves is described.

Abstract: A prosthetic device comprises a column formed of resilient material. The column comprises external protrusions that vary a girth of the column. The protrusions are separated by valleys that reduce bulk.

Abstract: A prosthetic device comprises stacked column segments. A first one of the column segments comprises a ball surface facing along a column axis. The ball surface has a generally convex shape that is articulable in a mating socket of a second one of the column segments. The first one of the column segments comprises a socket surface facing an opposite direction along the column axis. The socket surface has a generally concave shape that is articulable on a mating ball of a third one of the column segments. Multiple column segments similar to the first column segment are stacked to form the column.

Abstract: A body implantable penile prosthetic assembly includes a pump and a release mechanism. The pump is connectable to a pressure reservoir and a penile implant, where the pressure reservoir contains a pressurized liquid at a first pressure when implanted. The release mechanism is connectable between the pressure reservoir and the penile implant and is configured to release the pressurized liquid from the pressure reservoir to inflate the penile implant to a second pressure that is less than the first pressure. The pump is operable to transfer the pressurized liquid from the penile implant to the pressure reservoir to deflate the penile implant, and pressurize the pressurized liquid in the pressure reservoir from the second pressure to at least the first pressure.

Abstract: The present invention generally relates to methods, compositions and uses thereof for enhancing vascularization of a tissue or cell transplant for transplantation into a subject. In particular, one aspect of the present invention provides methods and compositions comprising the use of a population of stromal vascular fraction (SVF) cells to encapsulate or surround a tissue or cell transplant to enhance vascularization of the tissue or cell transplant. Another aspect of the present invention provides methods and compositions for enhancing vascularization of a tissue or cell transplant by combining a population of SVF cells with a tissue or cell transplant to form a transplant mixed with SVF cells.

Abstract: A method of preparing an opening formed in a penis for reception of a penile prosthetic includes measuring a length of the opening formed in the penis with a shaft of an instrument, and moving a dilation head longitudinally along the shaft of the instrument and dilating a diameter of the opening formed in the penis.

Abstract: According to various embodiments, an inflatable penile prosthesis (IPP) includes a rigidly constructed spool valve assembly that is used to direct fluid into and evacuate fluid out of the inflatable penile cylinders. The fluid transfer system transfers fluid from the fluid reservoir to the inflatable penile cylinders and includes the fluid transfer bulb, inlet valve, exhaust valve and spool valve assembly. The cylinder deflate mechanism evacuates fluid from the penile cylinders to the reservoir and includes the deflate actuator, return valve and spool valve assembly.

Abstract: A method of providing a user with a body implantable penile prosthetic includes providing a pump attachable to a pressure reservoir and a penile implant; pressurizing liquid in the pressure reservoir; configuring the pressure reservoir to release the pressurized liquid from the pressure reservoir to the penile implant at a first pressure for inflating the penile implant to an erect state; and pumping the pressurized liquid from the penile implant to the pressure reservoir and pressurizing the pressurized liquid to a second pressure greater than the first pressure.

Abstract: A body implantable penile prosthetic assembly includes a pump and a release mechanism. The pump is connectable to a pressure reservoir and a penile implant, where the pressure reservoir contains a pressurized liquid at a first pressure when implanted. The release mechanism is connectable between the pressure reservoir and the penile implant and is configured to release the pressurized liquid from the pressure reservoir to inflate the penile implant to a second pressure that is less than the first pressure. The pump is operable to transfer the pressurized liquid from the penile implant to the pressure reservoir to deflate the penile implant, and pressurize the pressurized liquid in the pressure reservoir from the second pressure to at least the first pressure.

Abstract: A method of implanting a penile prosthesis into a patient includes engaging a cap that is attached to a cylinder of the penile prosthesis with a distal end of a tool, and cradling the cylinder of the penile prosthesis between two support arms of the tool. The method additionally includes inserting the two support arms of the tool and the cylinder secured between the two support arms into a corpora cavernosum of the patient.

Abstract: An adapter is provided for holding a rear tip extender onto the cylinder of a penile prosthesis or onto another rear tip extender.

Abstract: A fluid reservoir for a penile implant device that includes a body portion having a sleeve from which a tube may extend. The body portion includes support structure positioned at an interior surface of the body portion near an orifice of the reservoir, which orifice leads to a fluid passage of the tube. The support structure may comprise a plurality of protrusions that are arranged around the orifice and that extend from a base portion of the body portion. The invention also relates to a method of manufacturing a fluid reservoir for a penile implant device, which includes positioning a tube in a mold and injection molding a reservoir body onto the tube. More particularly, the method may include providing a mold, positioning a tube in the mold, injecting material into the mold, curing the material, and opening the mold to remove the reservoir body and tube assembly.

Abstract: An instrument configured to prepare a penis for implantation of a penile prosthetic includes a shaft extending between a distal end and a proximal end, a plunger coupled to and movable relative to the shaft, and a dilation head coupled to a distal end of the plunger and disposed around an exterior'of the shaft. The dilation head is movable longitudinally along the shaft.

Abstract: A method of preparing an opening formed in a penis for reception of a penile prosthetic includes measuring a length of the opening formed in the penis with a shaft of an instrument, and moving a dilation head longitudinally along the shaft of the instrument and dilating a diameter of the opening formed in the penis.

Abstract: A cap configured to be attached to a cylinder of an implantable penile prosthesis includes a body section and a tip section. The body section defines a recess that is attachable to an end of the cylinder of the implantable penile prosthesis and the tip section terminates in a tip having a curved exterior surface. The tip section defines at least one slot formed therein that extends away from the body section and has a slot axis that intersects with a longitudinal axis of the cap.

Abstract: A pump connected to a body implantable penile prosthesis including a reservoir maintaining a fluid volume that is transferrable into a cylinder of the penile prosthesis is described. The pump includes a pump bulb connected to a pump body that is in fluid communication with the reservoir and the cylinder; an inlet valve operable to allow a portion of the fluid volume to be drawn from the reservoir and delivered into the pump bulb; an exhaust valve operable to allow the portion of the fluid volume delivered into the pump bulb to be pumped into the cylinder; and an anti-autoinflation (AAI) valve disposed in the pump body and comprising a seal that is biased to prevent fluid flow from bypassing the pump bulb and flowing from the reservoir to the cylinder.

Abstract: A method of providing a patient having a predetermined corporotomy length with an implant having a length that is sized for the predetermined corporotomy length is disclosed. The method includes providing a penile implant having a delivered length that is approximately equal to the predetermined corporotomy length and comprising a distance that extends from a distal end of a distal tip to a proximal end of a proximal tip assembly, the proximal tip assembly providing a first proximal tip diameter. The method additionally includes reducing the first proximal tip diameter to a smaller implantable proximal tip diameter.

Abstract: An implantable penile prosthesis system includes a penile prosthesis and an insertion tool. The penile prosthesis includes a cylinder extending between a distal tip and a proximal tip. At least one of the distal tip and the proximal tip has a pocket accessible by an opening, where the pocket is formed to extend laterally beyond a perimeter of the opening. The insertion tool extends between a distal end and a proximal end and includes an expansion mechanism coupled to the distal end. The opening in the tip(s) is sized to receive the distal end of the insertion tool and the expansion mechanism is configured to expand into the pocket to couple the insertion tool with the penile prosthesis.

Abstract: A male sexual impotence treatment apparatus comprises an operable restriction device (56) implanted in a patient and engaging the penile tissue (58) or the prolongation thereof to form a restrictable blood flow passageway through which blood flow leaves the penis. The restriction device is operable by an implanted operation device (60) to change the restriction of the blood flow passageway. A control device (62 and 64) is provided for controlling a source of energy, which may or may not be implanted, from outside the patient's body, to release energy for use in connection with the operation of the restriction device, i.e. to power the operation device. The patient uses the control device to restrict the blood flow leaving the penis to achieve erection.