Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more external optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The one or more optical emitters and the measurement apparatus may be moved together synchronously. The measurement apparatus may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: Disclosed is a bore based medical system comprising a camera carrier configured to be mounted in the bore based medical system and configured to monitor and/or track patient motion within said bore based medical system during radiotherapy, the bore based medical system comprising a rotatable ring-gantry configured to emit a radiotherapy beam focused at an iso-center of the bore based medical system, wherein the ring-gantry is configured to rotate at least partly around a through-going bore having a front side and a back side, configured to receive from said front side, a movable couch configured to be moved into and out from the through-going bore, wherein further the through-going bore comprises an inner side facing an inside of the bore, and wherein the camera carrier is configured to be mounted inside the bore in connection with the inner side of the through-going bore.

Abstract: Disclosed herein are systems and methods for identifying radiation therapy treatment data for patients. A processor accesses a neural network trained based on a first set of data generated from characteristic values of a first set of patients that received treatment at one or more first radiotherapy machines. The processor executes the neural network using a second set of data comprising characteristic values of a second set of patients receiving treatment at one or more second radiotherapy machines. The processor executes a calibration model using an output of the neural network based on the second set of data to output a calibration value. The processor executes the neural network using a set of characteristics of a first patient to output a first confidence score associated with a first treatment attribute. The processor then adjusts the first confidence score according to the calibration value to predict the first treatment attribute.

Abstract: A method for calculating during use the geometric parameters of an x-ray imaging system, an object or a patient to be observed being placed between the x-ray source and a detector of x-rays having passed through the object or patient, wherein it includes at least the following steps: detecting at least one marker on the object or the patient or in proximity to the object, the marker being of unknown 3D position, acquiring a plurality of 2D images for a plurality of viewpoints of the imaging system, detecting the position of at least one marker in each of the acquired 2D images, estimating the projection matrices corresponding to the projections of the object at various viewing angles and reconstructing in 3D the position of a marker on the basis of the estimation of the projection matrices.

Abstract: Disclosed is a console for operating an actuating mechanism, relating to the technical filed of automatic control, and being for use in resolving the technical problem of shift of a controller under the influence of gravity. The console for operating an actuating mechanism includes a controller and a support base. The controller is constrained in both the longitudinal direction and the vertical direction, so that connection between the controller and the support base is tight and reliable, and no displacement would occur in any of three directions (i.e., the longitudinal direction, the horizontal direction, and the vertical direction). Thus, the phenomenon that position information given by the controller is inaccurate due to shift of the controller under the influence of the gravity after long-term usage can be avoided, thereby removing the factors affecting success of surgery, and ensuring the success rate of the surgery.

Abstract: A contrast-enhanced digital tomosynthesis system with a source configured to emit penetrating particles toward an object, a detector configured to acquire a series of projection images of the object in response to the penetrating particles from the source, a positioning apparatus configured to position the source relative to the object and the detector, and an imaging system coupled to the source, the detector, and the positioning apparatus. The imaging system is configured to control the positioning apparatus to position the source and detector relative to the object, control the source and the detector to acquire the series of projection images, and construct a tomographic volume capable of exhibiting super-resolution morphology and contrast-enhancement arising from injection of an exogenous contrast agent from data representing the acquired series of projection images or a subset thereof.

Abstract: The present disclosure provides a common-path optical waveguide probe. The common-path optical waveguide probe includes an optical waveguide, a lens, and a reference reflector. The optical waveguide includes a proximal end and a distal end. The lens is coupled to the distal end. The reference reflector is positioned between the optical waveguide and the lens. The disclosure also provides a catheter and an optical coherence tomography system utilizing the common-path optical waveguide probe. The disclosure also provides methods of making and using the common-path optical waveguide probe.

Abstract: A system including a hierarchical analytics framework that can utilize a first set of machine learned algorithms to identify and quantify a set of biological properties utilizing medical imaging data is provided. System can segment the medical imaging data based on the quantified biological properties to delineate existence of perivascular adipose tissue. The system can also segment the medical imaging data based on the quantified biological properties to determine a lumen boundary and/or determine a cap thickness based on a minimum distance between the lumen boundary and LRNC regions.

Abstract: A medical image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to set a curved plane between a first bone region and a second bone region included in a joint, in three-dimensional medical image data obtained by imaging the joint including at least the first bone region and the second bone region. The processing circuitry is configured to reshape at least one of the first and the second bone regions along extension of the curved plane to obtain a reshaped bone region. The processing circuitry is configured to generate display-purpose image data on the basis of the reshaped bone region resulting from the reshaping.

Abstract: Provided is a technique for supporting a diagnosis in determining disease by using various types of measured values acquired by a medical image acquisition apparatus. An image diagnosis support device includes a measured-value receiving unit configured to receive various types of measured values at a plurality of positions within a living body, a group generator configured to generate groups of the measured values depending on the position or the type of the measured value, an intermediate index calculator configured to calculate an intermediate index from the measured values included in the group on a per-group basis, and a comprehensive index calculator configured to calculate a comprehensive index from values of the intermediate index calculated on a per-group basis. The intermediate index and the comprehensive index are displayed on a display unit in a display mode such as numerical values and in the form of an image.

Abstract: Methods and devices for controlling a robotic system includes receiving a signal in response to movement of an input device through an input distance, determining the position of a repositioning control disposed on the input device, and moving the tool of the robotic system in response to movement of the input device the input distance. The input device is coupled to an input shaft of an input arm. The robotic system moving the tool a first distance when the repositioning control is in a deactivated position and moves the tool a second distance when the repositioning control in an activated position. The first distance is greater than the second distance.

Abstract: Disclosed is a computer-implemented method for partitioning a medical image which encompasses acquiring a medical image of a surface of a patient and a surface of at least one object (embodied by image data), for example, by means of a 3D scanning device. Furthermore, a thermal image of the surface of the patient and the surface of the object is acquired (embodied by thermal data), for example, by means of a thermal camera. The medical image and the thermal image are fused (based on registration data), such that the image data is associated with the thermal data (embodied by association data). By analyzing the association data with regard to a specified condition (embodied by condition data), for example a condition related to a temperature threshold, a subset of the association data which fulfills the condition and describes a part of the medical image is determined (embodied by condition compliance data).

Abstract: A method of treating red blood cells of a human patient has the steps of activating an acoustic shock wave generator or source to emit acoustic shock waves and subjecting a vascular system containing red blood cells and surrounding muscle tissue peripherally through an extremity of a patient to the acoustic shock waves by stimulating the extremity wherein the extremity is positioned within a path of the emitted shock waves and away from a geometric focal volume or point of the emitted shock waves. The methods also treat muscle tissue of aging patients, from muscle regeneration or athletes for legal performance enhancement without drugs.

Abstract: A needle guide system for use with an ultrasound probe, the system comprising a surface marking guide and a needle guide. The surface marking guide includes an attachment portion for attaching the marking guide to an ultrasound probe, and a surface contact portion fixed to the attachment portion and including one or more features for identifying to a user where to mark a surface when the ultrasound probe is held against the surface. The needle guide includes a base to support the needle guide on the surface, one or more features on the base for alignment with marks made on the surface, and a needle support mounted on the base and having a needle channel through which a needle can extend, the needle channel having a known position and orientation relative to the base. We also describe a needle guide for use with an ultrasound probe to guide a needle along a predetermined path relative to the ultrasound probe.

Abstract: In order to improve the noise suppression in a video image stream 3 of a medical image recording system, the video image stream including a sequence of frames, it is provided that an image processing unit 5 of the image recording system analyses the video image stream 3 continuously in real time and determines at least one variability between successive image pixels of the frames, for example of spatially adjacent image pixels of frames and/or of image pixels of a plurality of the frames corresponding to one another spatially and temporally, in order, on the basis of the variability determined, to set at least one parameter of a noise suppression subsequently applied to the video image stream 3. As a result, the noise suppression can be adapted continuously to a current recording situation.

Abstract: Presented are systems and methods for the accurate acquisition of medical measurement data of a body part of patient. To assist in acquiring accurate medical measurement data, an automated diagnostic and treatment system provides instructions to the patient to allow the patient to precisely position a medical instrument in proximity to a target spot of a body part of patient. For a stethoscope examination, the steps may include utilizing object tracking to determine if the patient has moved the stethoscope to a recording site; utilizing DSP processing to confirm that the stethoscope is in operation, utilizing DSP processing to generate a pre-processed audio sample from a recorded audio signal; using machine learning (ML) to determine if a signal of interest (SOI) is present in the pre-processed sample. If SoI is present, using ML to evaluate characteristics in the signal which indicate the presence of abnormalities in the organ being measured.

Abstract: Where a flexible tool includes a tool body with a flexible portion, a distal end and a first optical fiber within the flexible portion, shape sensing can be achieved with increased accuracy by inserting or otherwise including a second optical fiber within the flexible portion. The increased accuracy can be achieved when the second optical fiber has a diameter larger than that of the first optical fiber. Once the shape of the flexible tool has been determined using at least the second optical fiber, the first optical fiber can be used for subsequent shape sensing. This may be particularly applicable where the tool includes an instrument such as an optical imaging device inserted in a channel of the tool, where not all of the width of the channel is occupied by functional components behind the operable end of the instrument.

Abstract: A physiological sensor for near-infrared spectroscopy at various depths includes elementary modules, each provided with at least one element chosen among transmitters of near infrared beams and receivers that are photosensitive in near-infrared, wherein each elementary module is connected to an adjacent elementary module by means of an articulation coupled to an angle sensor configured to measure the angle of inclination between the two elementary modules, wherein the elementary modules are assembled in order to form an optoelectronic layer that can be configured between a planar configuration in a main plane in which each articulation has an angle of inclination that is zero with respect to the main plane, and a plurality of curved configurations in which at least one of the articulations has an angle of inclination that is not zero with respect to the main plane.

Abstract: The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.

Abstract: A positioning unit for guiding a medical object such as a needle includes a securing unit by which the positioning unit may be arranged on the medical object. In order to enable an improved guidance for the medical object, an indicating element with a plurality of indicators is provided. The indicating element is arranged in a fixed position relative to the securing unit. An acquisition unit acquires an item of movement information. The positioning unit is configured to control the plurality of indicators dependent upon the movement information.

Abstract: Systems and methods that use computer vision techniques in connection with robotic surgery are discussed. A robotic surgery system may include an implantable device engagement sub-system, a targeting sub-system, and/or an insertion verification sub-system. The system may use computer vision techniques to facilitate implanting a micro-manufactured bio-compatible electrode device in biological tissue (e.g., neurological tissue such as the brain) using robotic assemblies. The system can attach, via robotic manipulation, the electrode to an engagement element of an insertion needle.

Abstract: An efficient direct parameter optimization (DPO) approach is provided, in which a dosimetry gradient-based iterative greedy technique is applied to determine positioning assistance information for catheter insertion in focal radiation therapy, by toggling between optimization of candidate catheter positions and candidate radiation source dwelling times. In the specific case of free hand delivered catheters, the insertion point may be directly selected by the human expert. Using monitoring of the catheter position by additional imaging modalities such as magnetic resonance imaging or ultrasound imaging, the method enables real-time orientation guidance and adaptive dose correction in the course of treatment delivery.

Abstract: The medical information display apparatus includes an image acquisition unit that acquires a first brain image which is a brain image of a subject captured at a first time point and a second brain image captured at a second time point later in time than the first time point, a registration unit that performs registration between the first and the second brain image, an image analysis unit that extracts a first cavity region and a second cavity region from the first brain image and the second brain image, respectively, a display unit, and a display controller displays, a cavity expansion part included in a first non-cavity region, which is a region other than the first cavity region, and included in the second cavity region in a distinguishable manner from a region other than the cavity expansion part from a result of the registration between the first and second brain image.

Abstract: An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a processor configured to obtain a computerized model of a plurality of vascular segments of a patient and create an unstenosed computerized model from the computerized model by virtually enlarging at least some locations of the vascular segments of the computerized model. The processor also determines vascular state scoring tool (“VSST”) scores based on characteristics of vascular locations along the vascular segments. The processor further determines a severity of stenosis for the vascular locations based on comparisons of first blood flow parameter values at the vascular locations in the computerized model to corresponding second blood flow parameter values at the same vascular locations in the unstenosed computerized model. A user interface of the device displays the severity of stenosis in conjunction with the VSST scores for the vascular locations.

Abstract: The invention relates to a system (1) for image based guidance of treatment delivery to a patient. The system is adapted to determine spatial parameters defining a position and orientation of an ultrasound probe (8) on the basis of a reference image which has been used for preparing a treatment plan. This can provide a certain degree of automation in arranging the ultrasound probe, in order to decrease user dependence and improve the usability for relatively untrained operators. Moreover, since the reference image is also used for generating the treatment plan, i.e. since the same image is used for generating the treatment plan and for determining the position and orientation of the ultrasound probe, it is not necessarily required to acquire an additional image. This can allow for a reduced radiation dose applied to the parts of the patient not being the target to be treated.

Abstract: A detection unit detects a region of a surgical tool in a radiographic image of a patient. In a case in which the surgical tool is detected, a display control unit displays the radiographic image on a display unit such that the detected region of the surgical tool is highlighted.

Abstract: A virtual reality system may generate a virtual robotic surgical environment using a client application, where the virtual robotic surgical environment includes at least one virtual robotic component. In response to a user input to move the at least one virtual robotic component in the virtual robotic surgical environment, the system may pass status information regarding the at least one virtual robotic component from the client application to a server application, generate an actuation command based on the user input and the status information using the server application, pass the actuation command from the server application to the client application, and move the at least one virtual robotic component based on the actuation command. The client application and the server application may be run on a shared processor device, or on separate processor devices.

Abstract: An intervention system employs an optical shape sensing tool (32) (e.g., a brachytherapy needle having embedded optical fiber(s)) and a grid (50, 90) for guiding an insertion of the optical shape sensing tool (32) into an anatomical region relative to a grid coordinate system. The intervention system further employs a registration controller (74) for reconstructing a segment or an entirety of a shape of the optical shape sensing tool (32) relative to a needle coordinate system, and for registering the needle coordinate system to the grid coordinate system as a function of a reconstructed segment/entire shape of the optical shape sensing tool (32) relative to the grid (50, 90) (i.e., reconstruction of a segment/entire shape of the OSS needle inserted into/through the grid serving as a basis for the grid/needle coordinate system registration).

Abstract: Systems and methods of measuring feet and designing and creating orthopedic inserts are described. A leg length discrepancy of a user is measured and this data, along with foot size are input into a computer. The computer then creates a computer model of a custom shoe insert based on this information. The computer model is then sent to a 3D printer to print the insert. The insert consists of a base insert with partial correction, and several additional layers that are added successively over time until a full correction is obtained. This eliminates any pain associated with a fully corrective insert, and allows the body to adjust gradually to the correction.

Abstract: A computer-implemented method for determining a target position of an X-ray device encompasses acquiring image data describing an anatomical structure of a patient, for example, by means of a 3D scan, and registering the image data relative to a coordinate system of the patient, for example by means of a navigation system. Furthermore, a trajectory of an implant positioned within the anatomical structure relative to the patient coordinate system is acquired. A target position of an X-ray device for acquiring an X-ray image of at least part of the implant is determined based on the registered image and the acquired trajectory of the implant.

Abstract: A brachytherapy treatment planning system includes a processor that: receives a planning image corresponding to at least a portion of a prostate; generates a brachytherapy treatment plan comprising, for each of a plurality of brachytherapy seeds or catheters, a corresponding brachytherapy seed or catheter position in the planning image such that the plurality of brachytherapy seed or catheter positions in the planning image together satisfy a desired radioactive dose objective in the prostate; receives a pre-treatment image corresponding to the at least a portion of a prostate; and maps each brachytherapy seed or catheter position in the planning image to a corresponding position in the pre-treatment image by performing a registration between the planning image and the pre-treatment image.

Abstract: An apparatus provides phase contrast X-ray image data of a region of interest of an object. Attenuation X-ray image data of the region of interest of the object is also provided. A first basis data set is generated from the phase contrast X-ray image data. A second basis data set is generated from the phase contrast X-ray image data and the attenuation X-ray image data.

Abstract: An MR imaging method with an imaging workflow is provided. Within the scope of the MR imaging method, at least one breath-holding command is output to a patient. An MR imaging is performed with an MR imaging method that may be used with free breathing. A breathing movement of the patient is detected based on measured data acquired when performing the MR imaging method. A time relationship is determined between the breathing movement of the patient and the breath-holding command. The imaging workflow is modified as a function of the determined time relationship. A breathing monitoring device and a magnetic resonance imaging system are also provided.

Abstract: A combined optical coherent tomography (OCT) pressure sensor system includes an optical cable comprising a single-mode core and a multi-mode core. An OCT optical imaging sensor near a distal end of the optical cable can be inserted into a lumen of a living being. First light exiting a distal end of the single-mode core illuminates an interior of the lumen. The OCT optical imaging sensor acquires image information about the interior of the lumen and transmits an optical signal carrying the image information into the distal end of the single-mode core, toward a proximal end of the single-mode core. An optical pressure sensor attached near the OCT optical imaging sensor receives second light from the distal end of the optical cable, senses ambient pressure within the lumen and transmits an optical signal indicative of the ambient pressure into a distal end of the multi-mode core, toward a proximal end of the multi-mode core.

Abstract: A method of processing plaques in magnetic resonance imaging of vessel wall include: step S101, training a generative adversarial network and a capsule neural network to obtain a trained generator network and a trained capsule neural network; and step S102, cascade-connecting the trained generator network with the capsule neural network into a system to recognize and classify plaques in magnetic resonance imaging of vessel wall. In one aspect, the capsule neural network has more abundant vascular plaques characteristic information represented by vector; in another aspect, when the trained generator network and the capsule neural network are cascaded into the system to recognize and classify the plaques in magnetic resonance imaging of vessel wall, an accuracy of recognition and classification may be greatly improved. A device for processing the method as well as a computer for implementing are also disclosed.

Abstract: Systems and methods for ambulatory detection of medical events such as cardiac arrhythmia are described herein. An embodiment of an arrhythmia detection system may include a detection criterion circuit that determines a patient-specific detection criterion using a baseline cardiac characteristic when the patient is free of cardiac arrhythmias. The detection criterion circuit generates a patient-specific threshold of a signal metric by adjusting a population-based threshold of the signal metric, where the manner and the amount of adjustment is based on information about patient baseline cardiac characteristic. The arrhythmia detection system detects an arrhythmia episode using a physiologic signal sensed from the patient and the patient-specific arrhythmia detection threshold.

Abstract: A method is described for planning intracorporeal positioning of a puncture needle to be introduced percutaneously into a patient on the basis of a puncture plan, said method comprising the following steps: a) arranging a needle guide means in a spatially fixed manner on the patient; b) generating and storing a series of cross-sectional images, each containing spatially resolved image information of the patient and of the needle guide means attached in a spatially fixed manner to the patient in a first coordinate system, using an imaging diagnostic method; c) selecting and visually displaying at least one cross-sectional image or a numerically generated cross-sectional image from the series of stored cross-sectional images; d) superimposing a virtual, positionally variable linear trajectory on the basis of the selected cross-sectional image; e) positioning the virtual linear trajectory on the basis of the puncture plan to obtain a target linear trajectory, in which the virtual linear trajectory traverses the

Abstract: A medical image processing apparatus, having a processor configured to divide brains included in a brain image and a standard brain image into a plurality of regions corresponding to each other, calculate a first correction amount between the pixel value of a first reference pixel included in each of the plurality of region in the brain image and the pixel value of a second reference pixel and a second correction amount for matching first other pixel values other than the first reference pixel included in each of the plurality of regions in the brain image with pixel values of second other pixels, and correct the brain image based on the first correction amount and the second correction amount.

Abstract: An image processing method, which is executed by a processor, comprises acquiring a choroidal vascular image, identifying, in the choroidal vascular image, a plurality of blood vessel center points of a choroidal blood vessel along a flow direction of the choroidal blood vessel, and computing a blood vessel diameter for each of the plurality of identified blood vessel center points.

Abstract: An example method for automating a quality assessment of digital fundus image can include: obtaining a digital fundus image file; analyzing a first quality of the digital fundus image file using a model to estimate an optimal time to capture a fundus image; and analyzing a second quality of the digital fundus image file using the model to estimate a disease state.

Abstract: A method for determining access to a patient for performing a surgical procedure in an internal location in the patient's body is disclosed. The method includes forming a three-dimensional model of a portion of the patient's body based on a set of medical images, calculating at least one path for a surgeon to follow to perform the surgical procedure, and determining one or more access zones that the surgeon may use to enter the body. Methods for assisting in the performance of a surgical procedure and performing the surgical procedure are also described and claimed.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: The invention relates to an apparatus for determining a relation between a surface motion of a body (BD) and an object motion of an object (OB) within the body (BD). The apparatus comprises a first sensing unit configured to acquire a first position signal indicative of a position of a first element placed at the location on the surface of the body with the surface motion; a second sensing unit configured to acquire a second position signal indicative of a position of a second element attached to an interventional device and placed on or in the object, wherein the first position signal and the second position signal are acquired during a given duration synchronously; and a third unit for calculating the relation between the surface motion and the object motion based on the first position signal and the second position signal. The invention also relates to a corresponding method for determining the motion relation.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of X-ray projection images; and while the gantry to continues to rotate to the second treatment delivery position, initiating delivery of a treatment beam of a treatment-delivering X-ray source mounted on the gantry to the target volume, and continuing to cause the gantry to rotate in the first direction from the second treatment delivery position to a third treatment delivery position.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.