With Therapeutic Device Patents (Class 600/439)
  • Patent number: 10772646
    Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.
    Type: Grant
    Filed: May 25, 2019
    Date of Patent: September 15, 2020
    Assignee: Xi'an Jiaotong University
    Inventors: Mingzhu Lu, Yizhe Geng, Ruixin Li, Xuan Wang, Yanshan Liu, Dan Han, Yehui Liu, Yujiao Li, Rui Wang, Mingxi Wan
  • Patent number: 10772655
    Abstract: The invention relates to an interstitial ultrasound ablation device (5) for being inserted into tissue surrounding, for instance, a tumor. The interstitial ultrasound ablation device comprises an arrangement (7) of ultrasound units (17, 18) for a focal ablation treatment which is modifiable from a folded configuration, to be used while inserting the ultrasound ablation device into the tissue, to an unfolded configuration, to be used after the ultrasound ablation device has been inserted into the tissue, such that the unfolded arrangement of ultrasound units is next to the tumor. This ultrasound ablation device can be easily positioned close to the tumor, where the unfolded arrangement of ultrasound units provides a large ultrasound emission area allowing for a very good focusing of the ultrasound on the tumor. This can lead to a very effective ablation of the tumor with only very few or no unwanted side effects.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: September 15, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Debbie Rem-Bronneberg
  • Patent number: 10765410
    Abstract: The present disclosure relates to the field of endoscopy. In particular, the present disclosure relates to systems and methods for real-time visualization of a target tissue, and which allows the location/orientation of the biopsy needle to be determined prior to its first actuation.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: September 8, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Austin G. Johnson, Sean Fleury
  • Patent number: 10758154
    Abstract: A method operates an image system of a medical imaging modality in which a patient data record of a patient is processed. A workflow for an examination is selected from a set of workflows on the basis of an examination specification of the patient data record. Wherein each workflow contains comprises a selection from a set of functions which are carried out in a specific temporal sequence.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: September 1, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Clemens Joerger, Gudrun Roth-Ganter
  • Patent number: 10751125
    Abstract: A focused-ultrasound or other procedure for treating a target within a tissue region can be planned iteratively by creating a treatment plan specifying a treatment location pattern and stimuli applied thereto, simulating the treatment, computationally predicting an effect of the simulated treatment, comparing the predicted effect against one or more treatment constraints (such as efficacy and/or safety thresholds), and, if a constraint is violated, repeating the simulation for an adjusted treatment plan.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: August 25, 2020
    Assignee: INSIGHTEC, LTD.
    Inventors: Yoav Levy, Benny Assif, Gilad Halevy, Yoni Hertzberg
  • Patent number: 10722169
    Abstract: A physiological state of a patient is detected by at least producing and detecting pressure waves with a free wall of an implantable medical device (IMD) housing. An actuator element may contact the free wall, e.g., a portion of the IMD housing, and cause movement of the free wall that produces a pressure wave within the fluid and tissue of the patient. A detector element contacting the free wall may in turn detect reflected pressure waves received by the free wall. An acoustic module within the IMD may then determine a physiological condition of the patient, e.g., a bladder fullness state, based on the time delay between the transmitted and reflected pressure waves. In some examples in which the IMD also delivers stimulation therapy to the patient, e.g., incontinence therapy, the IMD may also automatically adjust stimulation therapy based on the determined physiological condition.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: July 28, 2020
    Assignee: Medtronic, Inc.
    Inventors: Richard T. Stone, Xuan Wei
  • Patent number: 10722219
    Abstract: Systems and methods are provided for diagnosing neuromuscular disease in a patient suspected of having a neuromuscular disease, Phantoms for use in these systems and methods are also provided. Methods are further provided for determining a normalized ultrasound data value for a patient of interest having a known age, weight, height, and sex.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: July 28, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Andrea J. Boon
  • Patent number: 10722218
    Abstract: A method of generating a 3-D patient-specific bone model, the method comprising: (a) acquiring a plurality of raw radiofrequency (“RF”) signals from an A-mode ultrasound scan of a patient's bone at a plurality of locations using an ultrasound probe that comprises a transducer array; (b) tracking the acquiring of the plurality of raw RF signals in 3-D space and generating corresponding tracking data; (c) transforming each of the plurality of raw RF signals into an envelope comprising a plurality of peaks by applying an envelope detection algorithm to each of the plurality of raw RF signals, each peak corresponding with a tissue interface echo; (d) identifying a bone echo from the tissue interface echoes of each of the plurality of raw RF signals to comprise a plurality of bone echoes by selecting the last peak having a normalized envelope amplitude above a preset threshold, wherein the envelope amplitude is normalized with respect to a maximum peak existing in the envelope; (e) determining a 2-D bone contour f
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: July 28, 2020
    Assignee: JointVue, LLC
    Inventor: Mohamed R. Mahfouz
  • Patent number: 10709337
    Abstract: In a photoacoustic measurement apparatus and a photoacoustic measurement system, blood flow information in a desired region can be generated using a photoacoustic image. A light source emits measurement light. A probe detects a photoacoustic wave generated in a subject after measurement light is emitted to the subject in each of the avascularized condition in which the subject is avascularized and the non-avascularized condition in which the subject is not avascularized. Photoacoustic image generation unit generates a photoacoustic image based on the detection signal of the photoacoustic wave. Blood flow information generation unit generates blood flow information based on the signal value of a photoacoustic image in a region of interest set in the photoacoustic image.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: July 14, 2020
    Assignee: FUJIFILM Corporation
    Inventors: Dai Murakoshi, Kaku Irisawa, Tetsuro Ebata, Shoji Hara
  • Patent number: 10695798
    Abstract: The invention relates to a method for calibrating a treatment probe comprising at least one cylindrical transducer for generating high-intensity focused ultrasound in a target focus point, the probe being designed to be electrically connected to a power supply source for supplying an electrical signal for the power supply of the transducer, characterised in that the method comprises a step (20) of adjusting a frequency of the electrical signal for the power supply of the transducer in such a way that the variation between the maximum vibration intensity and the minimum vibration intensity of the transducer along the width thereof is minimal.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: June 30, 2020
    Assignee: EYE TECH CARE
    Inventors: Thomas Charrel, Laure Baffie
  • Patent number: 10675482
    Abstract: An intracranial treatment apparatus comprises an outer shaft having a proximal end and a distal end for positioning within the tissue region of the brain. The outer shaft defines a lumen extending between the proximal end and the distal end of the outer shaft and having at least one aperture adjacent the distal end of the outer shaft. An inner light-delivery element having a distal end and a proximal end is adapted to be operatively connected to the light source. The light-delivery element is configured to be received within the lumen and extend from the proximal end of the shaft to adjacent the distal end of the shaft. The light-delivery element is adapted to deliver light from the light source through the at least one aperture of the outer shaft to the tissue region of the brain in proximity to the distal end of the outer shaft.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: June 9, 2020
    Assignee: Craniovation, Inc.
    Inventors: Vijay Agarwal, Ranjith Babu, Jack Ratcliffe
  • Patent number: 10668299
    Abstract: A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 2, 2020
    Assignee: Nucletron Operations B.V.
    Inventors: Paulus Cornelis Hendrikus Maria Krechting, Wilhelmus Petrus Martinus Maria Van Erp, Jan F. L. De Becker, Anton J. G. Welberg
  • Patent number: 10667831
    Abstract: Disclosed herein are ultrasonic probes and systems incorporating the probes. The probes are configured to produce an ultrasonic therapy exposure that, when applied to a kidney stone, will exert an acoustic radiation force sufficient to produce ultrasonic propulsion. Unlike previous probes configured to produce ultrasonic propulsion, however, the disclosed probes are engineered to produce a relatively large (both wide and long) therapy region effective to produce ultrasonic propulsion. This large therapy region allows the probe to move a plurality of kidney stones (or fragments from lithotripsy) in parallel, thereby providing the user the ability to clear several stones from an area simultaneously. This “broadly focused” probe is, in certain embodiments, combined in a single handheld unit with a typical ultrasound imaging probe to produce real-time imaging. Methods of using the probes and systems to move kidney stones are also provided.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: June 2, 2020
    Assignees: University of Washington, Sonomotion, Inc.
    Inventors: Michael R. Bailey, Bryan Cunitz, Barbrina Dunmire, Adam Maxwell, Oren Levy
  • Patent number: 10667787
    Abstract: An ultrasound system comprising a portable ultrasound probe and a docking station provides enhanced ultrasound functionality. One or more first transducer elements transmit an ultrasound signal toward a target structure in a region of interest. Processing circuitry controls transmission of the ultrasound signal, while driving circuitry that is operatively coupled to the one or more first transducer elements and the processing circuitry drives the transmission of the ultrasound signal. The ultrasound probe further includes one or more second transducer elements that receive echo signals returning from the target structure in response to transmission of the ultrasound signal, and a power supply that provides power to the driving circuitry for transmission of the ultrasound signal. The docking station includes an interface that is couplable to the ultrasound probe and circuitry that electrically couples to the ultrasound probe via the interface and enhances the ultrasound functionality of the ultrasound probe.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: June 2, 2020
    Assignee: EchoNous, Inc.
    Inventors: Ron Broad, Todd Willsie, Greg Nieminen, Niko Pagoulatos
  • Patent number: 10661309
    Abstract: A dual frequency ultrasound transducer includes a high frequency ultrasound array and a low frequency transducer positioned behind or proximal to the high frequency ultrasound array. In one embodiment, a dampening material is positioned between a rear surface of the high frequency array and the a front surface of the low frequency array. The dampening preferably is high absorbing of signals at the frequency of the high frequency array but passes signals at the frequency of the low frequency transducer with little attenuation. In additional, or alternatively, the low frequency can angled with respect to the plane of the high frequency transducer to reduce inter-stack multipath reflections. Beamforming delays compensate for the differences in physical distances between the elements of the low frequency transducer and the plane of the high frequency transducer.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: May 26, 2020
    Assignee: FUJIFILM SonoSite, Inc.
    Inventors: Nicholas Christopher Chaggares, Guofeng Pang, Desmond Hirson
  • Patent number: 10646200
    Abstract: An intravascular ultrasound (IVUS) imaging system is provided. The IVUS imaging system includes an intravascular device including a transducer shaft with an ultrasound transducer at a distal end. The IVUS imaging system also includes an interface module removably coupled to the intravascular device. The interface module includes a connector rotatably coupled to a proximal end of the transducer shaft; a motor coupled to the connector; a spinning element coupled to the motor, wherein the spinning element comprises four conductive rings; a stationary element comprising a plurality of brushes, wherein the stationary element is disposed proximate the spinning element such that a different one of the plurality of brushes is in mechanical contact with each of the four conductive rings; and four conductors coupled to the connector and the spinning element such that the stationary element and the intravascular device are in electrical communication.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: May 12, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Sherwood Kantor, Douglas E. Meyer, Duane De Jong, Paul Hoseit
  • Patent number: 10639006
    Abstract: Disclosed is a focused ultrasound operation apparatus that includes: an operation hand piece that includes a handle unit that is used as a handle for a user; a cartridge that includes an ultrasound treatment unit, which generates a focused ultrasound, and has the shape of a circular cylinder or bar, the cartridge being attached to, and detached from, the operation hand piece; a window provided on the cartridge to pass the focused ultrasound generated by the ultrasound treatment unit; and a driver that drives the ultrasound treatment unit to move the ultrasound treatment unit forward and backward.
    Type: Grant
    Filed: September 2, 2015
    Date of Patent: May 5, 2020
    Assignee: HIRONIC CO., LTD.
    Inventors: Moon Seok Choi, Seon Tai Kim, Sung Won Lee, Jin Woo Lee, Jun Hyung Lee, Sang Hyeon Hwang, Tae Yun Kwon
  • Patent number: 10639052
    Abstract: The present disclosure provides a system for delivery of therapeutic energy. The system includes an energy unit configured to convert the acoustic energy signals transmitted to therapeutic ultrasound directed to fragment tumors and carcinogenic tissue in the body. The system also includes an energy unit configured to convert the acoustic energy signal transmitted from the energy unit to ultrasonic energy to image and monitor the treatment site with ultrasound. The system also includes a control unit including a computer for data storage and display.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: May 5, 2020
    Assignee: P Tech, LLC
    Inventor: Peter M. Bonutti
  • Patent number: 10639010
    Abstract: Provided are a puncture range determination apparatus and a puncture range determination method in which the hardness of tissue is considered as well as blood vessels. A blood vessel (32) is detected through performing Doppler processing. In addition, a soft region (33) of a subject is detected through performing elastication processing. A range of the soft region (33) excluding the blood vessel (32) is detected as a puncture recommendation range. Guide lines (34) and (35) defining the puncture recommendation range are displayed. A doctor performs puncturing with a needle inside the guide lines (34) and (35) and punctures a puncture target region (31) with the needle.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: May 5, 2020
    Assignee: FUJIFILM Corporation
    Inventor: Hiroaki Yamamoto
  • Patent number: 10639053
    Abstract: An endoscopic instrument is provided and includes a housing including an elongated shaft assembly extending distally therefrom. The elongated shaft assembly includes inner and outer shaft members. The inner and outer shaft members are removably coupled to the housing and the outer shaft member is movable with respect to the inner shaft member. An end effector is operably supported at the distal end of the outer shaft member and includes a pair of jaw members configured for treating tissue. A bushing operably couples to the inner and outer shaft members of the shaft assembly and selectively and releasably couples to the housing. The bushing includes one or more mechanical interfaces configured to engage one or more slots defined through the inner shaft member and one or more slots defined through the outer shaft member to release the inner and outer shaft members from the housing.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: May 5, 2020
    Assignee: COVIDIEN LP
    Inventors: Robert B. Stoddard, James S. Cunningham, William J. Dickhans, Russell D. Hempstead, Eric R. Larson, Duane E. Kerr, William H. Nau, Jr., Anthony B. Ross, John J. Kappus
  • Patent number: 10621305
    Abstract: A wireless medical room control arrangement includes a wireless controller having a wireless router. A room identifier and a device identifier are stored in the controller. A communication interface sends commands to and receives commands from the wireless controller. In response to commands from the interface, the wireless controller sends wireless control signals to operate medical devices in the room. A room monitor adjacent a doorway provides room identifiers to medical devices and wireless controllers entering the room and provides dummy identifiers to medical devices and controllers exiting the room. The room monitors may connect to a global network processor that determines the location of the medical devices in a medical facility.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: April 14, 2020
    Assignee: Stryker Corporation
    Inventors: Prabhu Raghavan, Travis Morgan
  • Patent number: 10610706
    Abstract: Methods and systems for treating skin, such as stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis or a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth with a conformal selective deposition of ultrasound energy without damaging an intervening tissue. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: April 7, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10610193
    Abstract: A system for continuous ultrasonic monitoring includes an ultrasound transducer. The ultrasound transducer includes an array of ultrasonic transducer elements. The ultrasonic transducer elements are operable to steer and focus an ultrasound beam to a selectable location and to receive an ultrasound signal from the selectable location. A holder is provided for holding the ultrasound transducer, the holder being attachable to a skin surface of a patient. A controller is configured to repeatedly steer and focus the ultrasound beam to identify a target section of an object inside the body of the patient and to acquire an ultrasound image such that the target section is maintained within the acquired ultrasound image.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: April 7, 2020
    Assignee: Hemonitor Medical Ltd.
    Inventors: Avinoam Bar-Zion, Tom Mayblum, Samer Toume
  • Patent number: 10610705
    Abstract: A probe for ultrasound treatment of skin laxity are provided. Systems and methods can include ultrasound imaging of the region of interest for localization of the treatment area, delivering ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and/or monitoring the treatment area to assess the results and/or provide feedback. In an embodiment, a treatment system and method can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal or deep dermal components of tissue.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: April 7, 2020
    Assignee: Guided Therapy Systems, L.L.C.
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10610197
    Abstract: A system for imaging and treating tissue comprises a probe having a deflectable distal tip for carrying an imaging array and a delivery needle for advancement within a field of view of the imaging array. Optionally, the needle will carry a plurality of tines which may be selectively radially deployed from the needle. The imaging array will preferably be provided in a separate, removable component.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: April 7, 2020
    Assignee: Gynesonics, Inc.
    Inventors: Robert K. Deckman, Brian Placek, Michael A. Munrow, Craig Gerbi, Jessica Grossman
  • Patent number: 10603519
    Abstract: Methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: March 31, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe
  • Patent number: 10603523
    Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: March 31, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin
  • Patent number: 10595819
    Abstract: A system for imaging and treating tissue comprises a probe having a deflectable distal tip for carrying an imaging array and a delivery needle for advancement within a field of view of the imaging array. Optionally, the needle will carry a plurality of tines which may be selectively radially deployed from the needle. The imaging array will preferably be provided in a separate, removable component.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: March 24, 2020
    Assignee: Gynesonics, Inc.
    Inventors: Robert K. Deckman, Brian Placek, Michael A. Munrow, Craig Gerbi, Jessica Grossman
  • Patent number: 10595821
    Abstract: Described herein are example ultrasonic transducer device probes configured to be placed on a patient's body to direct an ultrasonic beam towards an internal structure inside the body and receive ultrasonic echo signals from the internal structure. A probe includes a housing in which an ultrasonic transducer is located, a transceiving face of the transducer being at an acute angle relative to a front plane of the housing. An accelerometer unit and a magnetic field sensing unit are also housed inside the probe. The transducer, accelerometer, and magnetic field sensing unit are embedded in a body of a first material comprising ultrasound non-sonolucent material. A front face of the body of the first material and a recess extending down to the transceiving face is covered by a body of a second material comprising ultrasound sonolucent material having a tacky or non-tacky front surface.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: March 24, 2020
    Assignee: Respinor AS
    Inventors: Torgeir Hamsund, Morten Eriksen, Nicolas Souzy, Nicolay Berard-Andersen
  • Patent number: 10595944
    Abstract: A mobile surgical robotic cart assembly includes a vertical column supporting a robotic arm thereon, a base, and a plurality of casters each having wheels and each being attached to the base thereby allowing the surgical robotic assembly to move. Each of the plurality of casters has a wheel alignment assembly configured to lock each of the respective wheels in a plurality of orientations.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: March 24, 2020
    Assignee: COVIDIEN LP
    Inventor: James Lattimore
  • Patent number: 10589129
    Abstract: Various approaches for reducing microbubble interference with ultrasound waves transmitted from multiple transducer elements and traversing tissue onto a target region include measuring microbubbles in high-throughput areas of ultrasound exposure and reducing the amount of microbubbles using the ultrasound waves.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: March 17, 2020
    Assignee: INSIGHTEC, LTD.
    Inventors: Kobi Vortman, Shuki Vitek, Eyal Zadicario, Yoav Levy
  • Patent number: 10575819
    Abstract: A rotational intravascular ultrasound probe for insertion into a vasculature and a method of manufacturing the same. The rotational intravascular ultrasound probe comprises an elongate catheter having a flexible body and an elongate transducer shaft disposed within the flexible body. The transducer shaft comprises a proximal end portion, a distal end portion, a drive shaft extending from the proximal end portion to the distal end portion, an ultrasonic transducer disposed near the distal end portion for obtaining a circumferential image through rotation, and a transducer housing molded to the drive shaft and the ultrasonic transducer.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: March 3, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Stephen Charles Davies, Norman Hugh Hossack, Peter Howard Smith
  • Patent number: 10560725
    Abstract: An indication is received, from a content viewing device used by a remote viewer, that specifies a video content sub-area of interest within streamed video content viewed by the remote viewer. Original video content outside of the video content sub-area of interest is designated as a region not of interest (RNOI) within the streamed video content. A transmission rate of image changes of the original video content within the RNOI is reduced within the streamed video content. Image disparity between the video content sub-area of interest and the RNOI is reduced by continuing to transmit the image changes of the original video content within the RNOI at the reduced transmission rate. Bandwidth consumed to transmit the streamed video content is reduced in relation to the reduced transmission rate of the image changes of the original video content within the RNOI.
    Type: Grant
    Filed: December 9, 2018
    Date of Patent: February 11, 2020
    Assignee: International Business Machines Corporation
    Inventors: Kulvir S. Bhogal, Jonathan F. Brunn, Jeffrey R. Hoy, Asima Silva
  • Patent number: 10556132
    Abstract: The present invention comprises methods and devices for modulating the activity or activities of living cells, such as cells found in or derived from humans, animals, plants, insects, microorganisms and other organisms. Methods of the present invention comprise use of the application of ultrasound, such as low intensity, low frequency ultrasound, to living cells to affect the cells and modulate the cells' activities. Devices of the present invention comprise one or more components for generating ultrasound waves, such as ultrasonic emitters, transducers or piezoelectric transducers, composite transducers, CMUTs, and which may be provided as single or multiple transducers or in an array configurations. The ultrasound waves may be of any shape, and may be focused or unfocused.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: February 11, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventor: William James P. Tyler
  • Patent number: 10549127
    Abstract: Systems for nerve and tissue modulation are disclosed. An example system may include an intravascular nerve modulation system including an elongated shaft having a proximal end region and a distal end region. The system may further include a bar element extending distally from the distal end region of the elongated shaft and one or more ablation transducers affixed to the bar element.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: February 4, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Binh C. Tran, Mark L. Jenson
  • Patent number: 10542962
    Abstract: Radiation treatment is delivered to a patient by positioning the patient such that a radiation beam is delivered to a lesion within the patient along a beam-delivery path while securing a diagnostic imaging device about the patient such that the diagnostic imaging device does not intersect the beam-delivery path. Radiation therapy is simultaneously delivered along the beam-delivery path while diagnostic images are obtained using the imaging device.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: January 28, 2020
    Assignee: Elekta, LTD
    Inventors: Martin Lachaine, Sebastien Tremblay, Philippe Fortier, Sergei Koptenko, Tony Falco
  • Patent number: 10539539
    Abstract: In a method of using an ultrasonic sensor comprising a two-dimensional array of ultrasonic transducers, a plurality of ultrasonic signals are transmitted according to a beamforming pattern at a position of the two-dimensional array. The beamforming pattern focuses the plurality of ultrasonic signals to location above the two-dimensional array, wherein the beamforming pattern identifies ultrasonic transducers of the two-dimensional array that are activated during transmission of the ultrasonic signals, and wherein at least some ultrasonic transducers of the beamforming pattern are phase delayed with respect to other ultrasonic transducers of the beamforming pattern. At least one reflected ultrasonic signal is received at the position according to a receive pattern, wherein the receive pattern identifies at least one ultrasonic transducers of the two-dimensional array that is activated during the receiving. The transmitting and the receiving are repeated at a plurality of positions of the two-dimensional array.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: January 21, 2020
    Assignee: InvenSense, Inc.
    Inventors: Bruno W. Garlepp, Michael H. Perrott, James Christian Salvia
  • Patent number: 10532230
    Abstract: Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue on a face and/or neck are described.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: January 14, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10512446
    Abstract: A method and system for imaging, diagnosing, and/or treating an area of interest in a patient's body is provided. More particularly, a manually steered “rapid exchange” type catheter for a system for imaging, diagnosing, and/or an area of interest in a patient's body is provided. The catheter comprises a catheter body configured to be introduced to an area of interest in a patient's body, a device for imaging, diagnosing, and/or treating the area of interest contained within the catheter body, and a manual steering device attached to the imaging, diagnosing, and/or treating device to allow an operator to manually steer the imaging, diagnosing, and/or treating device, wherein the catheter is configured to be mounted on a commercially available guidewire.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: December 24, 2019
    Assignee: VOLCANO CORPORATION
    Inventors: Paul A. Magnin, Russell W. Bowden, John W. Goodnow
  • Patent number: 10466375
    Abstract: A method for automatic interpretation of bulls-eye and sinusoidal features observed in LWD images is disclosed. In some embodiments, the method includes an automatic workflow for extracting smooth contours from images that demarcate boundaries of structural features, followed by projection of the contours to three-dimensional (3D) point clouds in the well coordinate system for structural interpretation. The method may characterize both sinusoidal features and bulls-eye features, taking into account variations of formation dip/azimuth, or well inclination/azimuth, on the topology of a structural feature. The disclosed method may be sufficiently fast for use in real-time analysis and interpretation, or to provide constraints for physics-based data inversion processing.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 5, 2019
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Sushil Shetty, John Rasmus, Christopher Edward Morriss, Koji Ito, Shahzad Asif, Vittorio Picco
  • Patent number: 10456105
    Abstract: A catheter assembly for an ultrasound system includes an elongated catheter for insertion into the cardiovascular system of a patient. The catheter includes a sheath that defines a lumen extending along the sheath. The catheter assembly also includes an imaging core for inserting into the lumen of the catheter. The imaging core includes an elongated, rotatable driveshaft and an imaging device coupled to the distal end of the driveshaft with rotation of the driveshaft causing a corresponding rotation of the imaging device. The imaging device includes at least one transducer for transforming applied electrical signals to acoustic signals and also for transforming received echo signals to electrical signals. The imaging core further includes a swellable material disposed on at least the at least one transducer and configured and arranged to rotate with rotation of the driveshaft and to swell upon exposure to a fluid.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: October 29, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Xin Lu, Eric Elliott
  • Patent number: 10456557
    Abstract: An occlusion bypassing apparatus is disclosed for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The apparatus includes an outer shaft component, an inner shaft component disposed within the outer shaft component, and a needle component slidably disposed within the inner shaft component. The inner shaft component includes a body portion and a needle housing, which is distal to the body portion. The needle housing is less flexible than the body portion. In order to smooth the transition between the body portion and the needle housing, the needle housing includes a transition portion that has a variable flexibility along its length that decreases in a distal direction. A curved distal end of the needle component is distally advanced relative to the inner shaft component to pierce through the intima of the vessel and thereafter enter the true lumen.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: October 29, 2019
    Assignee: Invatec S.p.A.
    Inventors: Carlo Guala, Claudio Silvestro, Massimo Morero, Giovanni Scalvini
  • Patent number: 10448837
    Abstract: A system and method for mapping interluminal structures includes an elongated flexible instrument (102). An optical shape sensing device (152, 154) is disposed within the flexible instrument and is configured to determine a shape of the flexible instrument relative to a reference. The shape sensing device is configured to collect information based on its configuration to map an interluminal structure during a procedure. An imaging enabled ablation device (117) is mounted at or near a distal end portion of the flexible instrument.
    Type: Grant
    Filed: August 17, 2011
    Date of Patent: October 22, 2019
    Assignee: KNONKLIJKE PHILIPS N.V.
    Inventors: Robert Manzke, Raymond Emmanuel Chan, Adrien Desjardins, Gert Wim 'T Hooft, Szabolcs Deladi
  • Patent number: 10441499
    Abstract: Devices and methods for generating acoustic shock wave within a cavity is disclosed. The shock wave device optionally includes a housing having a cylindrical portion and a cone frustum portion. The housing optionally forms a cavity configured to receive a body appendage. The shock wave device optionally includes a plurality of shock wave generators and a coupling assembly having a deformable sac configured to hold shock wave transmitting liquid. The volume of the transmitting liquid is optionally increased or decreased as needed so that the coupling assembly can conform to the shape of the body appendage. The shock waves generated optionally has an intensity gradient within the cavity of the shock wave device, where the intensity gradient is optionally controllable using a control and power supply unit.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: October 15, 2019
    Assignee: S-WAVE CORP.
    Inventors: Da Zhu, Zhuoyu Chen
  • Patent number: 10441314
    Abstract: Systems and methods related to the location of target regions in imaging applications are generally described. Certain embodiments relate to devices and/or methods for image-guided identification of suitable regions at which to insert needles, catheters, and the like. Such systems and methods can be used in association with a variety of imaging technologies, including ultrasound imaging. In certain embodiments, the systems and methods described herein can be used in association with hand-held ultrasound imaging devices.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: October 15, 2019
    Assignee: Rivanna Medical LLC
    Inventors: Daniel Lee Bizzell, Raeshon Lamont McNeil, Juan Carlos Perez
  • Patent number: 10433814
    Abstract: A system and method for providing image guidance for placement of one or more medical devices at a target location. The system can determine one or more intersections between a medical device and an image region based at least in part on first emplacement data and second emplacement data. Using the determined intersections, the system can cause one or more displays to display perspective views of image guidance cues, including an intersection indicator in a virtual 3D space.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: October 8, 2019
    Assignee: InnerOptic Technology, Inc.
    Inventors: Sharif Razzaque, Luv Kohli, Andrei State, Brian Heaney, Kurtis Keller, Caroline Green
  • Patent number: 10433906
    Abstract: Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage pulses to drive irreversible electroporation for minimally invasive transurethral prostate ablation. In one embodiment, a switch unit is used to modulate and apply voltage pulses from a cardiac defibrillator, while in another, the system controller can be configured to apply voltages to an independently selected multiplicity or subsets of electrodes. Devices are disclosed for more effective DC voltage application including the infusion of cooled fluid to elevate the irreversible electroporation threshold of urethral wall tissue and to selectively ablate regions of prostate tissue alone.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: October 8, 2019
    Assignee: Farapulse, Inc.
    Inventor: Steven R. Mickelsen
  • Patent number: 10426974
    Abstract: The generation of a pattern and for an adaptation to the specific geometry requires a lot of manual work. The workflow for the clinician is simplified during treatment planning. A treatment planning system is configured for determining a set of catheter or needle insertion positions to be used during treatment. The treatment planning system includes an image providing module for providing a medical image from which at least one treatment target structure can be derived. Further the treatment planning system includes a pattern providing module for providing one or a set of standard patterns for catheter or needle insertion including a plurality of catheter or needle insertion positions. The catheter or needle positions relate to treatment positions in the at least one treatment target structure.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: October 1, 2019
    Assignees: KONINKLIJKE PHILIPS N.V., SUNNYBROOK RESEARCH INSTITUTE (SRI)
    Inventors: Thomas Erik Amthor, Falk Uhlemann, SHyam Bharat, Ehsan Dehghan Marvast, Cynthia Ming-Fu Kung, Ananth Ravi, Jochen Kruecker
  • Patent number: 10426499
    Abstract: During shock wave therapy, a determination is made that a kidney stone has begun to fracture, and then a progress of its fragmentation is assessed. This determination can reduce the number of shock waves used to disintegrate kidney stones, and thereby reduce dose-dependent tissue damage. The identification of fracture is possible through the detection and analysis of resonant acoustic scattering, which is the radiation caused by reverberations within a stone particle that is struck by a shock wave. The scattering frequency can provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Related concepts employ displacement measurements of kidney stones/fragments to provide both an indication that the kidney stone has fragmented, and an indication of the relative sizes of the fragments. Such techniques can be combined with vibro-acoustography based gating that better targets the stone.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: October 1, 2019
    Assignee: University of Washington
    Inventors: Neil Owen, Michael Bailey, Oleg Sapozhinikov
  • Patent number: 10420961
    Abstract: A method of operating a device (1) for treatment of a tissue (6) of a living being and such a device (1) including a transducer (2) comprising at least two subtransducers (2?, 2?), each for emitting a sub-beam (8?) of ultrasound waves, preferably high intensity focused ultrasound waves, for irradiating the tissue (6). Each of the sub-beams (8?) is focused on or focusable onto a focal point (F). In order to reduce skin burns, the intersection Area (Asi) of a skin surface (7) for each sub-beam (8?) is evaluated and a power (Psi) and/or a duration (tsi) of the irradiation, for every sub-transducer (2?, 2?), is determined as a rate of the total power (Ptotal) or duration (ttotal) depending from the evaluated intersection area (Asi).
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: September 24, 2019
    Assignee: Theraclion SA
    Inventor: Francois Lacoste