Abstract: An ultrasonic transmitter unit includes: a sheath that forms a cylindrical shape and is having a proximal end and a distal end; an ultrasonic transmitter configured to be inserted into the sheath; and a cover member that covers a part of the ultrasonic transmitter and has an inner surface and an outer surface. The ultrasonic transmitter includes: a first area surrounded by the sheath; a second area protruding from the distal end of the sheath; and a distal-end treatment portion provided in a distal end of the second area. The cover member covers the second area of the ultrasonic transmitter, and exposes the distal-end treatment portion of the ultrasonic transmitter to an outside, and is made of fluorine-based resin.

Abstract: An ultrasound probe positioning system (100) comprises a positioning unit (102) for holding an ultrasound probe unit (104) and for moving the ultrasound probe unit and positioning it at a target position and a positioning control unit (106) configured to provide target positioning data indicative of a target position that establishes a mechanical contact of the ultrasound probe unit with an external object (110) and to control the mechanical positioning unit in moving and positioning the ultrasound probe at the target position. The positioning unit comprises a force actuation unit (108) configured to adapt a pressing force amount of a mechanical pressing force exerted on the object in response to a variation of a counterforce amount so as to maintain a predetermined net pressing force amount exerted by the mechanical pressing force against the counterforce.

Abstract: In accordance with the present disclosure, deep-learning techniques are employed to find anomalies corresponding to bleed events. By way of example, a deep convolutional neural network or combination of such networks may be trained to determine the location of a bleed event, such as an internal bleed event, based on ultrasound data acquired at one or more locations on a patient anatomy. Such a technique may be useful in non-clinical settings.

Abstract: An ultrasound system including: a scanner module including a housing including a first fastener element, an ultrasound transducer, a rotational actuator, and an electronics module; and a positioner module including a second fastener element; operable between a first mode, wherein the first and second fastener elements cooperatively couple the scanner module to the positioner module, and a second mode, wherein the scanner module and positioner modules are separate. An ultrasound system including: a housing including a handle region and a membrane; an ultrasound transducer; a reservoir; a rotational actuator; and an electronics module.

Abstract: A method for adjusting the operation of a surgical instrument using machine learning in a surgical suite is disclosed. The method comprises the steps of gathering data during surgical procedures, wherein the surgical procedures include the use of a surgical instrument, analyzing the gathered data to determine an appropriate operational adjustment of the surgical instrument, and adjusting the operation of the surgical instrument to improve the operation of the surgical instrument.

Abstract: An ultrasonic endoscope includes: an ultrasonic transducer having an ultrasonic vibrator; a distal end portion body disposed continuously with a proximal end side of the ultrasonic transducer; an erecting base housing portion that is disposed in the distal end portion body and has an opening which opens toward one side in a direction perpendicular to the axial direction of the distal end portion body; a treatment tool lead-out port that communicates with the inside of the erecting base housing portion, an erecting base that is disposed in the inside of the erecting base housing portion and changes a lead out direction of a treatment tool led out from the treatment tool lead-out port; and a cleaning communication hole that is formed in a wall surface on a side opposite to a side where the opening of the erecting base housing portion is disposed and communicates with an outside.

Abstract: An ultrasound imaging and therapy device includes an array of concentric annular ultrasound transducers, and an ultrasound imaging device situated inside an innermost transducer of the plurality of concentric annular ultrasound transducers, wherein it further comprises a mechanical linkage allowing a tilting movement of the array of concentric annular ultrasound transducers with respect to the ultrasound imaging device and in that the ultrasound imaging device protrudes in an axial direction from the array of concentric annular ultrasound transducers; whereby the ultrasound imaging device can be kept stationary and in direct or indirect contact with a patient's skin while the array of concentric annular ultrasound transducers is tilted so as to move a focal point of ultrasound waves generated by the concentric annular ultrasound transducers within an imaging region of the ultrasound imaging device.

Abstract: An interventional therapy system may include at least one catheter configured for insertion within an object of interest (OOI); and at least one controller which configured to: obtain a reference image dataset including a plurality of image slices which form a three-dimensional image of the OOI; define restricted areas (RAs) within the reference image dataset; determine location constraints for the at least one catheter in accordance with at least one of planned catheter intersection points, a peripheral boundary of the OOI and the RAs defined in the reference dataset; determine at least one of a position and an orientation of the distal end of the at least one catheter; and/or determine a planned trajectory for the at least one catheter in accordance with the determined at least one position and orientation for the at least one catheter and the location constraints.

Abstract: A method for planning a scan path for intraoperative radiation therapy may comprise acquiring a plurality of images of a region of interest through an auxiliary scanning component, establishing a 3D model of the region of interest based on the plurality of images of the region of interest, determining a radiation therapy volume based on the 3D model of the region of interest, and planning a scan path for a radiation therapy component to scan the radiation therapy volume.

Abstract: The present disclosure discloses a method and an apparatus for acquiring motion information. A frequency domain transformation is performed on a detection signal of a vibration propagating in a medium to obtain a frequency domain signal, then a signal that is outside of a defined vibration velocity range is removed from the frequency domain signal, that is, only a vibration signal is retained, and then a position-time diagram is obtained along a defined vibration propagation direction. It is not necessary to perform motion estimation on propagation of the vibration by a complicated calculation, and it is only necessary to determine the presence or absence of the vibration by processing in the frequency domain, and then the position-time diagram is obtained, which is a highly efficient method for acquiring motion information.

Abstract: A method and apparatus that utilizes a force-time integral for real time estimation of steam pop in catheter-based ablation systems. The apparatus measures the force exerted by a contact ablation probe on a target tissue and an energization parameter delivered to the ablation probe. The exerted force and energization parameter can be utilized to provide an estimation of the probability of steam pop. In one embodiment, the force and energization metrics can be used as feedback to establish a desired contact force and energization level combination to prevent steam popping.

Abstract: Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

Abstract: A high-low intensity focused ultrasound treatment apparatus according to the present disclosure includes a plurality of ultrasound sources, and a controller to control a center frequency and intensity of focused ultrasound outputted from the ultrasound sources, wherein each of the ultrasound sources includes a first ultrasound transducer to output low-intensity focused ultrasound to detect a lesion, and a second ultrasound transducer to output high-intensity focused ultrasound to ablate or remove the detected lesion. The low-intensity focused ultrasound outputted from the first transducer may be used to detect a lesion in a patient's brain by applying a stimulus to the brain, and at the same time, investigating a response, and the high-intensity focused ultrasound outputted from the second transducer may be used to ablate or remove the detected lesion by applying a thermal or mechanical stimulus to the lesion.

Abstract: A non-transitory computer-readable recording medium stores therein a learning program that causes a computer to execute a process including: generating a shadow image including a shadow according to a state of ultrasound reflection in an ultrasound image; generating a combined image by combining the ultrasound image and the shadow image; inputting, into a first decoder and a second decoder, an output acquired from an encoder in response to inputting the combined image into the encoder; and executing training of the encoder, the first decoder, and the second decoder, based on: reconfigured error between an output image of a coupling function and the combined image, the coupling function being configured to combine a first image output from the first decoder with a second image output from the second decoder, and an error function between an area in the first image and the shadow in the shadow image.

Abstract: A compact, integrated acoustic localization and communications array includes an air-backed transmit element having a first end on which an end cap is disposed, and a second end configured to be mounted to a mounting surface. A volumetric acoustic array including a plurality of receiver elements that is electrically integrated to the transmit element. The localization and communications array is configured to transmit, via the transmit element, and receive, via the plurality of the receiver elements, an acoustic signal having a frequency in the range of 10 kHz to 50 kHz. Each of the plurality of receiver elements are spaced apart from the end cap at least a distance. The distance is greater than ¼ of a wavelength associated with the frequency transmitted and received by the localization and communications array, and is not equal to an odd multiple of ¼ of the wavelength.

Abstract: Apparatuses, systems, and techniques are provided for modular ultrasonic transducers and frame. An ultrasonic transducer array may include a modular ultrasonic transducer array frame. The modular ultrasonic transducer array frame may include mechanisms for the attachment of ultrasonic transducer modules to the ultrasonic transducer array frame. The ultrasonic transducer array may include ultrasonic transducer modules which may include arrays of ultrasonic transducer elements within the ultrasonic transducer modules. Two of the ultrasonic transducer modules may include arrays of ultrasonic transducer elements where the ultrasonic transducer elements are different between the two ultrasonic transducer modules.

Abstract: A needle assembly for use with an ultrasound imaging system includes a needle having a proximal end and a distal end. The distal end is adapted to be inserted into a patient. The needle assembly also includes a transducer mounted to an exterior surface of the needle at the distal end. Further, the needle assembly includes a flexible printed circuit board mounted on the exterior surface of the needle from the proximal end to the distal end. As such, the flexible printed circuit board electrically connects the transducer to a power source.

Abstract: An ultrasonic sensor includes a two-dimensional array of ultrasonic transducers, a contact layer, a matching layer between the two-dimensional array and the contact layer, where the matching layer has a non-uniform thickness, and an array controller configured to control activation of ultrasonic transducers during an imaging operation for imaging a plurality of pixels within the two-dimensional array of ultrasonic transducers. During the imaging operation, the array controller is configured to activate different subsets of ultrasonic transducers associated with different regions of the two-dimensional array of ultrasonic transducers at different transmission frequencies, where the different frequencies are determined such that a thickness of the matching layer at a region is substantially equal to a quarter wavelength of the first transmission frequency for the region.

Abstract: Various methods and systems are provided for thermal monitoring of tissue with an ultrasound imaging system. In one embodiment, a method comprises acquiring, via an ultrasound probe, an ultrasound image, selecting at least one region of interest in the ultrasound image, extracting features from the at least one region of interest, classifying a thermal state of tissue in the at least one region of interest based on the features, and outputting, via a display device, the thermal state of the tissue. In this way, ultrasound imaging may be used for real-time thermal monitoring of tissue during an ablation procedure, thereby improving the accuracy and efficacy of the ablation procedure.

Abstract: This invention pertains a system and methods for ablation treatment of tissues. The invention aims to aid healthcare professionals in completely treating all the target tissues by fusing computer generated information highlighting which tissues have been treated and which not to images of the tissues. The systems and methods integrate seamlessly with current image-guided procedures and do not require tracking systems to gather the position of the ablation device, as the positon and orientation of the device are identified from images. The invention aims also to improve estimates of the ablation volumes associated to an ablation device by identifying from images the true geometry of devices that might deform during the deployment in tissues; the invention aims to improve estimates of the ablation volumes by using information about the ablation process and about the status of tissues which can be collected from the control system of the ablation device.

Abstract: An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The device also includes an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly is configured to obtain imaging data of the body lumen. The ultrasound imaging assembly includes a transducer array including a substrate, a silicon oxide layer disposed over the substrate, and a plurality of rows of micromachined ultrasound transducer elements disposed on the silicon oxide layer. Two of the plurality of rows of micromachined ultrasound transducer elements are spaced apart by a trench formed by etching through a screen formed in the silicon oxide layer. Associated devices, systems, and methods are also provided.

Abstract: An ultrasound transmitter device for treating a patient is provided. The ultrasound transmitter device includes an imaging probe; an imaging array; and a therapeutic ultrasound device, wherein the imaging probe is configured to guide the therapeutic ultrasound device to the patients treatment site by use of ultrasound imaging with the imaging array, wherein the therapeutic ultrasound device is configured to produce a controlled intensity of ultrasound energy for treating the patients treatment site, and wherein the imaging probe and the therapeutic ultrasound device are configured to work in conjunction with one another to apply therapeutic ultrasound to tissue or bone graft sites in the patient.

Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.

Abstract: An ultrasonic imaging system is provided which can obtain an accurate synthesized image, even if a specimen has a surface with a large curvature. An ultrasonic imaging system may include a probe and processing circuitry. The probe may perform scan of first and second ultrasonic waves different from each other. The processing circuitry may generate a first ultrasonic image based on the first ultrasonic wave and generate a second ultrasonic image based on the second ultrasonic wave. The processing circuitry may calculate a spatial relationship based on two first ultrasonic images at two positions and two second ultrasonic images at the two positions. The processing circuitry may synthesize one of the first and second ultrasonic images at one of the two positions with the one of the first and second ultrasonic images at the other position based on the calculated relationship.

Abstract: In one aspect, devices for image guided laparoscopic surgery are disclosed. Such devices can comprise a shaft, a surgical component, a handle, and one or more sensors. The shaft comprises a proximal end and a terminal end that opposes the proximal end. The surgical component is disposed at the terminal end of the shaft, and the handle extends from the proximal end of the shaft. The handle comprises one or more actuating components configured to actuate the surgical component. The one or more sensors are disposed on or over the handle, and are configured to detect and/or track movement of the handle and/or actuation of one or more of the actuating components.

Abstract: Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing microbubbles having the first size distribution such that at least 50% of the microbubbles have a radius smaller than a critical radius corresponding to a resonance frequency matching the selected frequency of ultrasound waves; and applying the ultrasound waves at the selected frequency to treat the target tissue.

Abstract: A method of estimating a spatial relationship between at least a part of a patient esophagus and a heart chamber, including: measuring at least one electric parameter at one or more positions within the heart chamber to obtain measured values; and estimating the spatial relationship based on the measured values.

Abstract: A needle guide apparatus for endocavity ultrasound intervention is provided, comprising a plastic bracket and a needle guiding passage made of metal that is provided in the plastic bracket, wherein the plastic bracket has a mounting structure that is detachably mounted to an endocavity ultrasound probe, and the needle guiding passage comprises a needle insertion groove provided by a metal head and a guiding groove provided by a metal guiding tube, the metal guiding tube is at least partially housed in the plastic bracket, and at least an inlet end of the metal head is exposed outside the plastic bracket. The needle guide apparatus for endocavity ultrasound intervention forms an all-metal needle guiding passage in the plastic bracket, so that the needle can smoothly and cleanly enter the human body during the ultrasonic interventional operation, and the interventional operation is safe, reliable and easy to operate.

Abstract: A method of imaging a vessel with a catheter includes positioning an imaging tip in a reinforced terminal section of an outer sheath of the catheter, inserting the catheter into a vessel, and performing near infrared spectroscopy of the vessel by retracting the imaging tip to a retracted position proximally spaced from the reinforced terminal section of the outer sheath, transmitting near infrared light from the imaging tip to the vessel wall via the outer sheath, and collecting near infrared light from the vessel wall at the imaging tip via the outer sheath. Transmitting and collecting may be performed after retracting the cable and while the imaging tip is rotated and translated proximally from the retracted position along the outer sheath. Ultrasound energy may be transmitted to the vessel from a transducer on the imaging tip and received from the vessel at the transducer.

Abstract: Disclosed herein is an ultrasonic probe having improved heat dissipation capability. The ultrasonic probe includes a housing, an acoustic module disposed in the housing, and configured to transmit an ultrasonic signal to an object and receive an signal reflected from the object, an electronic circuit disposed in the housing and electrically connected to the acoustic module to drive the acoustic module, and a hole communicating an outside of the housing with the electronic circuit so that the electronic circuit is cooled by air outside the housing.

Abstract: Methods of positioning a surgical instrument can involve advancing a first medical instrument to a treatment site of a patient, the first medical instrument comprising a camera, recording a target position associated with a target anatomical feature at the treatment site, generating a first image of the treatment site using the camera of the first medical instrument, identifying the target anatomical feature in the first image using a pretrained neural network, and adjusting the target position based at least in part on a position of the identified target anatomical feature in the first image.

Abstract: A therapeutic ultrasound system transmits a staggered or interleaved pattern of therapy beams for use in sonothrombolysis and other Vascular Acoustic Resonators (VAR) mediated therapy. The inventive technique minimizes VAR, e.g. microbubble, destruction due to adjacent beams, ensures uniform sonication of the targeted region by filling in the spaces between the beams in subsequent passes, and further provides a means for bubble replenishment to maximize the clot lysis from ultrasound. The technique is also applicable to diagnostic ultrasound, VAR mediated drug delivery and blood brain barrier opening.

Abstract: Provided is a device that transmits and receives an ultrasonic wave to and from an entire periphery of a specimen while preventing a movement of the specimen. An ultrasonic wave transmission and reception device includes: an oscillator array that is arrayed with an oscillator, the oscillator transmitting and receiving an ultrasonic wave; a fixing tool that is disposed between the oscillator array and the specimen and retains the specimen; and a drive mechanism that presses at least a part of the fixing tool against the specimen as to retain the specimen. An ultrasonic wave transmitted by the oscillator array passes through the fixing tool and irradiates on the specimen, and as for the oscillator array, the oscillator array and the fixing tool are disposed in a positional relationship such that the ultrasonic wave reflected by and/or passing through by the specimen and passing through the fixing tool is received.

Abstract: A device and method for visualization of the intravascular creation of autologous valves, and particularly venous valve, is disclosed herein. One aspect of the present technology, for example, is directed toward a delivery catheter that can include a lumen configured to receive a dissection assembly and a trough having a plurality of transducers electrically coupled to a proximal portion of the delivery catheter. At least one of the transducers can be configured to emit a signal towards a portion of a blood vessel adjacent the trough, and at least one of the transducers can be configured to receive a reflection of the emitted signal.

Abstract: Provided is a method of displaying location information of a bursa, which includes: obtaining shoulder ultrasound image data; detecting a fat layer located between a deltoid muscle and a tendon, based on information about an intensity of an echo signal contained in the shoulder ultrasound image data; detecting the bursa located between the fat layer and the tendon by using a location of the fat layer; and displaying the location information of the bursa on a shoulder ultrasound image generated based on the shoulder ultrasound image data.

Abstract: The present invention relates to a treatment apparatus and a method of controlling the same, and provides a treatment apparatus including an insertion unit formed in such a way as to be inserted into a tissue through a tissue surface, a bending sensing unit sensing bending of the insertion unit occurring during insertion, and a controller controlling the insertion operation of the insertion unit based on information sensed by the bending sensing unit, and a method of controlling the same. In accordance with the present invention, there is an advantage in that a treatment effect can be improved because treatment can be performed in the state in which the insertion unit has been inserted into an accurate target location.

Abstract: Systems and methods for targeting specific cell types by selective application of ultrasonic harmonic excitation at a resonance frequency (“oncotripsy”) for the specific cell types are presented. The systems and the methods result in permeabilization, lysis, and/or death of the targeted specific cell types by using ultrasonic harmonic excitations that have a frequency and a pulse duration specifically tuned to disrupt nuclear membranes of the targeted specific cell types by inducing a destructive vibrational response therein while leaving non-targeted cell types intact. Target cells may be neoplastic.

Abstract: Described here are systems and methods for estimating shear wave velocity from data acquired with a shear wave elastography system. More particularly, the systems and methods described here implement a spatiotemporal time-to-peak algorithm that searches for the times at which shear wave motion is at a maximum while also searching for the lateral locations at which shear wave motion is at a maximum. Motion can include displacement, velocity, or acceleration caused by propagating shear waves. A fitting procedure (e.g., a linear fit) is performed on a combined set of these temporal peaks and spatial peaks to estimate the shear wave velocity, from which mechanical properties can be computed. Motion amplitude thresholding can also be used to increase the number of points for the fitting.

Abstract: Ultrasound devices, and associated methods of assembly thereof, are disclosed whereby an annular electrode array of an ultrasound transducer is electrically connected to a flexible printed circuit board in a compact configuration. The flexible circuit board includes an elongate flexible segment and a distal distribution segment, where the distribution segment is attached to a peripheral support ring that surrounds at least a portion of the ultrasound transducer. The distribution segment includes a plurality of spatially distributed contact pads, and electrical connections are provided between the contact pads and the annular electrodes of the annular array.

Abstract: A system and method for planning surgical procedure including importing CT image data of a patient; generating a 3D reconstruction from the CT image data; presenting a slice of the 3D reconstruction; selecting a target anatomical feature from the slice of the 3D reconstruction; setting a treatment zone including presenting at least one slice of the 3D reconstruction including the target anatomical feature, and presenting a treatment zone marker defining a location and a size of the treatment zone on the presented at least one slice of the 3D reconstruction; setting an access route to the treatment zone; and presenting a three-dimensional model including the treatment zone and the access route.

Abstract: A control handle of a treatment probe is manipulated to advance and/or deploy one or more treatment structures into tissue. The treatment probe is coupled to a display to show an image field including target tissue for treatment. Virtual treatment and safety boundaries are overlaid over the image field. The boundaries include virtual stop positions for the needle and tines. A joystick or directional pad on the probe handle, operable independently from the user interface to advance and/or deploy the one or more treatment structures, can be manipulated to adjust the size and/or position of these boundaries. Sensors within the probe detect the real-time position of the one or more treatment structures, and the sensed positions are displayed in real-time. The user can observe the display to deploy the one or more treatment structures to the displayed virtual stop positions.

Abstract: Disclosed is an ultrasound image processing apparatus (5) comprising an image processor arrangement (50) adapted to receive a first sequence (100?) of ultrasound images (150) imaging an anatomical feature of interest (151) during a first full cardiac cycle in the absence of an invasive medical device (15) in said ultrasound images, each ultrasound image corresponding to a different phase of said cardiac cycle; receive a further sequence (100) of ultrasound images (150) imaging the anatomical feature of interest (151) during a further full cardiac cycle in the presence of the invasive medical device (15) in said ultrasound images, each ultrasound image corresponding to a different phase of said cardiac cycle said invasive medical device (15) at least partially obscuring the anatomical feature of interest, and for each ultrasound image of the further sequence: track the location of the invasive medical device in the ultrasound image; isolate the invasive medical device from the ultrasound image; and insert the

Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.

Abstract: A probe for ultrasound treatment of skin laxity are provided. Systems and methods can include ultrasound imaging of the region of interest for localization of the treatment area, delivering ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and/or monitoring the treatment area to assess the results and/or provide feedback. In an embodiment, a treatment system and method can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal or deep dermal components of tissue.

Abstract: An ultrasound exposure safety processor is configured for spatially relating respective definitions of an imaging zone, and an extended dead-tissue zone that includes both a dead-tissue zone and a surrounding margin. Based on whether a push pulse focus is to be within the extended dead-tissue zone, the processor automatically decides a level of acoustic power with which the pulse is to be produced. If the pulse focus is to be within the extended dead-tissue zone, the pulse may be produced with a mechanical index (MI), a thermal index (TI), and/or a spatial-peak-temporal-average intensity (IspTA) that exceeds respectively 1.9, 6.0 and 720 milliwatts per square centimeter. The imaging zone may be definable interactively to dynamically trigger the deciding and the producing, with push pulse settings being dynamically derived automatically. A display of multiple push pulse sites allows user manipulation of spatial definition indicia to dynamically control displacement tracking.

Abstract: A system and method for acquiring magnetic resonance (MR) images, with an MR system, of tissue proximal to a target treatment region in a patient, the tissue including a non-spatially uniform subcutaneous fat layer; in a computer comprising a hardware-based processor, automatically determining a thickness of the subcutaneous fat layer using a trained neural network, the neural network trained using manually-segmented MR images from previous patients; in the computer, automatically adjusting a treatment parameter based on the thickness of the subcutaneous fat layer; and delivering thermal therapy to the target treatment region with a high-intensity focused ultrasound system based on the adjusted treatment parameter.

Abstract: A system and method for providing image guidance for placement of one or more medical devices at a target location. The system can determine one or more intersections between a medical device and an image region based at least in part on first emplacement data and second emplacement data. Using the determined intersections, the system can cause one or more displays to display perspective views of image guidance cues, including an intersection indicator in a virtual 3D space.

Abstract: A medical instrument includes a shaft, one or more position sensors, a connector and interrogation circuitry. The shaft is configured for insertion into a body of a patient. The one or more position sensors are fitted at a distal end of the shaft. The connector is configured to receive a mating connector. The interrogation circuitry is configured to detect whether the mating connector is connected to the connector, and, if not connected, to prevent tracking a position of the distal end in the body using the one or more position sensors.

Abstract: Systems and methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.

Abstract: A laser catheter with a pressure sensor is provided according to embodiments of the invention. The pressure sensor may be coupled with the distal end of the laser catheter and may comprise any of various piezoelectric materials, for example Polyvinylidene Difluoride (PVDF). In various embodiments of the invention the pressure sensor is configured to detect pressure longitudinally and coaxially. The pressure sensor may provide an electric potential that is proportional to the vessel pressure and may be used to monitor and/or adjust laser parameters. In other embodiments the results from the pressure sensor may be used to determine the vessel size and/or the type of material being ablated.