With Therapeutic Device Patents (Class 600/439)
  • Patent number: 11123575
    Abstract: An approach for enhancing radiation treatment of target tissue includes identifying a target volume of the target tissue; causing disruption of vascular tissue in a region confined to the target volume so as to define the target volume; based at least in part on the disruption of the vascular tissue, determining a radiation treatment plan having a reduced radiation dose for treating the target tissue; and exposing the target volume to the reduced radiation dose based on the radiation treatment plan.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: September 21, 2021
    Assignee: INSIGHTEC, LTD.
    Inventors: Kobi Vortman, Yoav Levy
  • Patent number: 11116383
    Abstract: The present invention provides a structured-light based system for providing a 3D image of at least one object within a field of view within a body cavity, comprising: a. An endoscope; b. at least one camera located in the endoscope's proximal end, configured to real-time provide at least one 2D image of at least a portion of said field of view by means of said at least one lens; c. a light source, configured to real-time illuminate at least a portion of said at least one object within at least a portion of said field of view with at least one time and space varying predetermined light pattern; and, d. a sensor configured to detect light reflected from said field of view; e. a computer program which, when executed by data processing apparatus, is configured to generate a 3D image of said field of view.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: September 14, 2021
    Assignee: Asensus Surgical Europe S.à.R.L.
    Inventors: Tal Nir, Motti Frimer, Gal Atarot
  • Patent number: 11109776
    Abstract: A system and method include a shape sensing enabled device (120) including one or more imaging devices (202), the shape sensing enabled device coupled to at fiber (122). A shape sensing module (132) is configured to receive optical signals from the at least one optical fiber within a structure and interpret the optical signals to determine a shape of the shape sensing enabled device. A device positioning module (134) is configured to determine position information of the one or more imaging devices based upon one or more relationships between the at least one optical fiber and the one or more imaging devices. A mapping module (136) is configured to register frames of reference of the at least one optical fiber, the shape sensing enabled device, and a mapping system of a target device (124) to provide an adjusted position of the target device based on the position information.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: September 7, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Shyam Bharat, Cynthia Ming-fu Kung, Jochen Kruecker
  • Patent number: 11097131
    Abstract: A probe for treating an ocular pathology. The probe has a ring including a cone frustum having a first end suitable for supporting an ultrasound generator and a second end for coming into contact with an eye of a patient. The ultrasound generator includes a first base intended to come to face the first end, and a second base opposite the first base. The probe further includes a flow regulator for eliminating the bubbles contained in a coupling fluid flowing to the first base when filling the probe with the fluid.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 24, 2021
    Assignee: EYE TECH CARE
    Inventors: Phillipe Chapuis, Thomas Charrel, Cedric Devigne, Nicolas Laisney, Arash Razavi Mashoof
  • Patent number: 11083439
    Abstract: Cooling units for an ultrasound imaging apparatus, and related ultrasound systems are described. The ultrasound imaging systems may include an ultrasound imaging apparatus operable to acquire ultrasound image data; and a cooling unit configured to detachably couple to the ultrasound imaging apparatus. The cooling unit may be cordless and include an active cooling element for removing heat from the ultrasound imaging apparatus. The ultrasound imaging apparatus may have a sensor to determine when the cooling unit is attached. The cooling unit may have an identity interface, and the ultrasound imaging apparatus may use the identity interface to determine whether the cooling unit is compatible.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: August 10, 2021
    Assignee: Clarius Mobile Health Corp.
    Inventors: Kwun-Keat Chan, Binda Zhang, Daniel Rahardja
  • Patent number: 11071594
    Abstract: In certain embodiments, the systems, apparatus, and methods disclosed herein relate to robotic surgical systems with built-in navigation capability for patient position tracking and surgical instrument guidance during a surgical procedure, without the need for a separate navigation system. Robotic based navigation of surgical instruments during surgical procedures allows for easy registration and operative volume identification and tracking. The systems, apparatus, and methods herein allow re-registration, model updates, and operative volumes to be performed intra-operatively with minimal disruption to the surgical workflow. In certain embodiments, navigational assistance can be provided to a surgeon by displaying a surgical instrument's position relative to a patient's anatomy.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: July 27, 2021
    Assignee: KB Medical SA
    Inventors: Szymon Kostrzewski, Jean-Marc Wismer, Daniel Gehriger, Roderik Berthelin, Chetan Patel
  • Patent number: 11045169
    Abstract: A device comprises a cannula having a first end, a second end, and a channel between the first end and the second end; an imaging probe couplable to the first end of the cannula, where the imaging probe includes: a transducer, and a reflective surface; and a biopsy device coupled to the cannula, where the biopsy device is configured to collect a tissue sample from an organ of a patient.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: June 29, 2021
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Barbara Smith, Joel Barkley, Christopher Miranda
  • Patent number: 11022501
    Abstract: Systems and methods for measuring temperature characteristics of a battery include one or more transducers coupled to the battery for transmitting and/or receiving sound waves through at least a portion of the battery. A temperature measurement unit is provided to determine a time-of-flight of sound waves through at least the portion of the battery based on transmitted and received sound waves through at least the portion of the battery, and to determine temperature characteristics of at least the portion of the battery based on the time-of-flight.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: June 1, 2021
    Assignee: Feasible, Inc.
    Inventors: Andrew Gaheem Hsieh, Barry James Van Tassell, Daniel Artemis Steingart, Shaurjo Biswas, Robert Charles Mohr
  • Patent number: 11013889
    Abstract: Medical devices and methods for making and using medical devices are disclosed. An example system for delivering an implantable medical device includes a handle member including a seal assembly, wherein the seal assembly includes a turnbuckle assembly including a stationary member and a cap coupled to the stationary member. Further, the stationary member is coupled to an inner member and the cap is coupled to an exoskeleton disposed along an outer surface of the inner member. Additionally, the cap is designed to shift relative to the stationary member such that the exoskeleton is put in compression.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: May 25, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Kevin Robert Poppe, Daniel J. Foster, Christopher Jay Scheff, Bradley S. Swehla
  • Patent number: 11006924
    Abstract: Systems and methods for stroke detection in accordance with embodiments of the invention are illustrated.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 18, 2021
    Assignee: BURL Concepts, Inc.
    Inventors: Thomas Francis Doyle, Thilo Hoelscher, James Brailean, Maximillian Dirnbacher, Arne Voie, Mark Banham, Balaji Simma, Jeffry Tola
  • Patent number: 11007016
    Abstract: An intracardiac ultrasound catheter or other intravascular imaging tool is provided with an adapter to allow the imaging tool to be used both subcutaneously and supracutaneously, and especially at different stages of a single intravascular procedure. The adapter covers a tip of the imaging tool and preferably includes an echogenic window to facilitate gathering of ultrasound images through this window in the adapter. With the adapter in place, the intracardiac ultrasound can be used supracutaneously, such as at a femoral artery/vein location for imaging to improve vascular access, such as with an appropriate percutaneous needle. The adapter is then removed and the same imaging tool can be inserted percutaneously and intravascularly for use, such as in intracardiac imaging accompanying and intracardiac procedure. The intracardiac ultrasound probe is preferably coupled to an electrophysiology mapping system both when used supracutaneously and when used intravascularly.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: May 18, 2021
    Inventor: Walter Kusumoto
  • Patent number: 11000308
    Abstract: The present disclosure is directed to a fluid cooled ultrasonic surgical instrument and related systems and methods of use therefor. In some embodiments, the disclosed ultrasonic surgical instrument is adapted for used within an insufflated cavity or pneumoperitoneum of a patient. The instrument includes a housing having an elongate shaft, a waveguide disposed at a distal end of the shaft, a coolant inlet port defined in an outer surface of the housing, and a coolant pump disposed within the housing and configured to move coolant from the coolant inlet port to the waveguide. During use, insufflation gas from within the pneumoperitoneum is drawn into the instrument shaft by the coolant pump, and blown over the waveguide to provide cooling. The delivery of ultrasonic energy and activation of the pump may be controlled by a processor in response to user input and waveguide temperature.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: May 11, 2021
    Assignee: Covidien LP
    Inventors: Anthony B. Ross, Robert B. Stoddard, James S. Cunningham, William J. Dickhans, Russell D. Hempstead, Eric R. Larson, Duane E. Kerr, William H. Nau, Jr., Arlen K. Ward
  • Patent number: 10987492
    Abstract: A guidewire providing imaging and light for photoactivation of therapeutic agents. Using optical fibers with Bragg gratings, electromagnetic waves are coupled to photoacoustic materials thereby providing acoustic energy for imaging tissues. The reflected acoustic waves can be sensed with photoreflective materials coupled to different optical fibers. Additional optical fibers allow photoactivated therapeutics to be activated in proximity to the imaged tissues. The photoactivated therapeutics may be administered intravenously or with a drug-delivery catheter.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: April 27, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Paul Hoseit
  • Patent number: 10987087
    Abstract: An ultrasound endoscope is provided with an insertion portion to be inserted into a subject along a first direction which is an insertion direction. The ultrasound endoscope includes: a transducer having a scanning surface that scans with an ultrasound wave along a second direction; a supply pipeline configured to supply an ultrasound wave transfer medium; and a rigid member connected to a proximal end side of the transducer, the rigid member formed with a scanning surface supply port configured to supply the ultrasound wave transfer medium supplied from the supply pipeline in a direction intersecting with the first direction and the second direction.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: April 27, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Kazuya Saiga
  • Patent number: 10973400
    Abstract: Provided is an optical fiber scanner capable of generating an image with excellent image quality, which displaces an emission end of an optical fiber by means of an optical scanning actuator and scans light emitted from the optical fiber, in which the optical fiber 31 includes a photonic crystal fiber at least in a propagation path of the light leading to the optical scanning actuator.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: April 13, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Hiroyoshi Yajima
  • Patent number: 10969487
    Abstract: Methods of triggering an imaging acquisition of a target region in an ultrasound transducer include: acquiring a first type of ultrasound data with the ultrasound transducer using a first type of ultrasound acquisition; analyzing the first type of ultrasound data to identify an acquisition time and/or position having characteristics that increase an estimated amount of image quality metrics in the target region for a second type of ultrasound acquisition; and generating a signal to initiate acquiring a second type of ultrasound data by the ultrasound transducer at the identified acquisition time and/or position using a second type of ultrasound acquisition in response to the identified acquisition time and/or position identified from the first type of ultrasound data.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: April 6, 2021
    Inventors: Gregg Trahey, Willie Long, Peter Hollender, David Bradway, Vaibhav Kakkad, Nicholas Bottenus
  • Patent number: 10966750
    Abstract: A needle assembly positionable within anatomy of a patient under visual guidance from an ultrasound system. The needle assembly includes an elongate body and a sidewall including an inner surface defining a lumen. A reverberation feature may include opposing portions of the inner surface defining a gap shaped differently than and/or sized smaller than an inner diameter of the lumen. The reverberation feature is configured to reverberate an incident wave to produce reflected waves, from which a visual artifact is generated with the ultrasound system. The opposing portions may be disposed at superior and inferior aspects of the sidewall. The reverberation feature may include opposing planar surfaces oriented parallel or inclined relative to a longitudinal axis, and/or opposing arcuate surfaces extending towards the longitudinal axis. Methods of positioning the needle assembly near target anatomy of a patient, for example within a vessel, under visual guidance are disclosed.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: April 6, 2021
    Inventor: Andrew J. Butki
  • Patent number: 10960235
    Abstract: A method and system for energy-based (e.g., ultrasound treatment and/or other modalities) of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound (or other energy) through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: March 30, 2021
    Assignee: Guided Therapy Systems, LLC
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10952637
    Abstract: A method includes receiving, from a probe that comprises electrodes and is positioned inside a cavity in an organ of a patient, (i) proximity signals indicative of proximity of the electrodes to a wall of the cavity, and (ii) position signals indicative of positions of the electrodes within the cavity. Based on the proximity signals and the position signals, at least a portion of a volume of the cavity is represented by a sphere model including multiple spheres. An estimated contour of the wall of the cavity is calculated based on the sphere-model. The estimated contour of the wall is presented to a user.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: March 23, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Andres Claudio Altmann, Vadim Gliner, Alon Boumendil
  • Patent number: 10945793
    Abstract: The present teaching relates to surgical procedure assistance. In one example, a first image of a patient captured prior to a surgical procedure is received. A treatment plan is generated based on the first image. The treatment plan includes information related to one or more surgical instruments. A second image of the patient captured after the surgical procedure has been initiated is received. The treatment plan is dynamically adjusted based on a pose of any of the one or more surgical instruments identified from the second image. A third image of the patient captured after a lesion is treated by at least one of the surgical instruments based on the adjusted treatment plan is received. Whether a further treatment to the lesion is needed is determined based on the third image. Upon determining a further treatment is needed, an updated treatment plan is dynamically generated based on the third image.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: March 16, 2021
    Assignee: EDDA TECHNOLOGY, INC.
    Inventors: Guo-Qing Wei, Cheng-Chung Liang, Li Fan, Jian-Zhong Qian, Xiaolan Zeng
  • Patent number: 10945729
    Abstract: A robotic surgical system comprising a surgical robot, a surgical instrument, a motor, and a current sensor is disclosed. The surgical instrument comprises an end effector, a firing assembly, and a lockout mechanism. The firing assembly comprises a firing member movable from an unfired position to a fired position during a firing stroke and a sled movable from a proximal position to a distal position. The lockout mechanism is configured to prevent the firing stroke when the sled is not in the proximal position. The motor is operably coupled with the firing member and couplable with a supply of current. When the current through the motor exceeds a threshold value the firing member is prevented from completing the firing stroke. The threshold value corresponds to the current through the motor when the lockout mechanism is activated. The motor is de-energized when the current through the motor exceeds the threshold value.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: March 16, 2021
    Assignee: Ethicon LLC
    Inventors: Frederick E. Shelton, IV, James R. Giordano
  • Patent number: 10939826
    Abstract: The invention generally relates to devices and methods for imaging and aspirating biological material from inside a vessel. In certain embodiments, the invention provides devices that include a body configured to fit within a lumen of a vessel. The body includes an opening. Devices of the invention also include an aspiration channel within the body. The aspiration channel includes a distal end that is connected to the opening. Devices of the invention also include an imaging assembly coupled to the body.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: March 9, 2021
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Timothy K. Glynn, Jeremy Stigall, Maritess Minas
  • Patent number: 10925512
    Abstract: The embodiments described herein relate to devices, systems and methods for in-vivo diagnosis of disease-state tissue within a body.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: February 23, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Russell P. Dresher
  • Patent number: 10928628
    Abstract: An optical fiber scanning apparatus includes an optical fiber a fixed end of which is fixed and a free end for emitting illumination light of which vibrates in a first direction and a second direction, a ferrule which includes a through hole including an opening on a distal end surface and fixes the optical fiber inserted through the through hole, a pair of first fixing members which sandwich and fix the optical fiber in the first direction, a pair of second fixing members which sandwich and fix the optical fiber in the second direction, and piezoelectric elements or a magnet configured to vibrate the optical fiber, in which a Young's modulus of the pair of first fixing members is smaller than a Young's modulus of the pair of second fixing members.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: February 23, 2021
    Assignee: OLYMPUS CORPORATION
    Inventor: Masanori Ogata
  • Patent number: 10918386
    Abstract: A surgical instrument is disclosed. The instrument includes an end effector comprising a moveable cutting instrument to cut an object and a motor coupled to the end effector. The motor actuates the cutting instrument in response to a current therethrough, causing the cutting instrument to move between a proximal-most position and a distal-most position. The instrument includes an interlock coupled to the end effector and to the motor to prevent actuation of the cutting instrument based on the current through the motor.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: February 16, 2021
    Assignee: Ethicon LLC
    Inventors: Frederick E. Shelton, IV, James R. Giordano
  • Patent number: 10888717
    Abstract: A method and system for providing ultrasound treatment to a tissue that contains a lower part of dermis and proximal protrusions of fat lobuli into the dermis. An embodiment delivers ultrasound energy to the region creating a thermal injury and coagulating the proximal protrusions of fat lobuli, thereby eliminating the fat protrusions into the dermis. An embodiment can also include ultrasound imaging configurations using the same or a separate probe before, after or during the treatment. In addition various therapeutic levels of ultrasound can be used to increase the speed at which fat metabolizes. Additionally the mechanical action of ultrasound physically breaks fat cell clusters and stretches the fibrous bonds. Mechanical action will also enhance lymphatic drainage, stimulating the evacuation of fat decay products.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: January 12, 2021
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe, Inder Raj S. Makin
  • Patent number: 10888716
    Abstract: Systems and methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell. The lesion can create an opening in the surface of the fat cell, which allows the draining of a fluid out of the fat cell and through the opening. In addition, by applying ultrasound energy to fat cells to increase the temperature to between 43 degrees and 49 degrees, cell apoptosis can be realized, thereby resulting in reduction of fat.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: January 12, 2021
    Assignee: Guided Therapy Systems, LLC
    Inventors: Michael H. Slayton, Peter G. Barthe
  • Patent number: 10888718
    Abstract: A probe for ultrasound treatment of skin laxity are provided. Systems and methods can include ultrasound imaging of the region of interest for localization of the treatment area, delivering ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and/or monitoring the treatment area to assess the results and/or provide feedback. In an embodiment, a treatment system and method can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal or deep dermal components of tissue.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: January 12, 2021
    Assignee: Guided Therapy Systems, L.L.C.
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10881482
    Abstract: Operation room devices, methods, and systems are disclosed. One method comprises: receiving, at a processing unit, data associated with a patient; determining, with the processing unit, a treatment for the patient; identifying, with the processing unit, a control setting associated with one or more treatment devices that are (i) in communication with the processing unit, and (ii) operable to perform the treatment; and generating, with the processing unit, a display including the control setting and at least one view of the data. Related devices and systems also are disclosed.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: January 5, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Niraj Rauniyar, Timothy Harrah, Peter J. Pereira, Eric Wong, William Stanhope, Brian MacLean, Brandon Craft, Stuart Perry, William Gastrock
  • Patent number: 10874877
    Abstract: Aspects herein are directed to an anchorable brachytherapy device configured to be permanently implanted in a tumor bed at the time of operative removal of the tumor. In example aspects, the brachytherapy device may comprise a plurality of hollow tubes that form a spherical or ellipsoid shape. Protrusions or grooves may be formed on an outer surface of the tubes to help anchor the brachytherapy device in the tumor bed. Radioactive seeds or strands may be positioned within the tube channels to provide radiation to the tumor bed.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: December 29, 2020
    Assignee: POSITIVE ENERGY, LLC
    Inventor: Ibrahim Abdalla
  • Patent number: 10874455
    Abstract: Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate an ovarian artery of an ovary of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the polycystic ovary syndrome. Ovarian sympathetic nerve activity can be modulated along afferent and/or efferent pathways. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: December 29, 2020
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventor: Paul Sobotka
  • Patent number: 10869727
    Abstract: An interventional procedure can be performed less invasively with live 3D holographic guidance and navigation. Advantageously, the 3D holographic guidance and navigation overcomes the limitations of conventional displays of medical images on standard 2D flat panel screens. The live 3D holographic guidance can utilize a 3D holographic visualization that is derived from complementary imaging modalities (e.g., ultrasound and computed tomography) to provide a complete holographic view of a portion of the patient's body to enable navigation of a tracked interventional instrument/device.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: December 22, 2020
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Jeffrey H. Yanof, Karl West, Sara Al-Nimer
  • Patent number: 10864034
    Abstract: An ablation catheter comprises: an elongated catheter body extending longitudinally between a proximal end and a distal end along a longitudinal axis; a distal member disposed adjacent the distal end, the distal member including an ablation element to ablate a biological member; one or more acoustic transducers disposed in the distal member and each configured to direct an acoustic signal toward a respective target ablation region and receive reflection echoes therefrom; and an acoustic redirection member disposed in the distal member to at least partially redirect the acoustic signal from at least one of the acoustic transducers toward a tissue target. The distal member includes a most-distal portion, a proximal portion, and a deflectable portion between the most-distal portion and proximal portion to permit deflection between the most-distal portion and proximal portion of the distal member. The transducers and redirection member are mounted on opposite sides of the deflectable portion.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: December 15, 2020
    Assignee: St. Jude Medical, LLC
    Inventors: John W. Sliwa, Zhenyi Ma, Stephen A. Morse
  • Patent number: 10864385
    Abstract: Systems and methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Lifting sagging tissue on a face, neck, and/or body are described. Treatment with heat is provided in several embodiments.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: December 15, 2020
    Assignee: Guided Therapy Systems, LLC
    Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin
  • Patent number: 10856845
    Abstract: An ultrasound diagnosis device includes: an ultrasound probe which transmits an ultrasound wave toward a examinee and receives a reflected wave from the examinee; and a main device which controls the transmitting and receiving of the ultrasound waves from the ultrasound probe and is operated to receive a receiving signal obtained by receiving the reflected wave from the examinee by the ultrasound probe, to generate an ultrasound image of the examinee, and to display the ultrasound image on a display screen, wherein the ultrasound probe includes a plurality of subarrays having a plurality of element circuits transmitting and receiving ultrasound signals and a plurality of reference voltage sources, and the plurality of subarrays and the plurality of reference voltage sources have a one-to-one correspondence.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: December 8, 2020
    Assignee: HITACHI, LTD.
    Inventors: Yusaku Katsube, Tatsuo Nakagawa, Yasuyuki Okuma, Yohei Nakamura, Takahide Terada, Shinya Kajiyama, Takuma Nishimoto, Yutaka Igarashi
  • Patent number: 10843012
    Abstract: An ultrasound apparatus is described for externally treating kidney stone in human body. The apparatus has one or more ultrasound imaging transducers, a therapeutic ultrasound transducer, and a processing unit. Optimized delivering of ultrasound energy to the kidney stone from the therapeutic ultrasound transducer is based on real-time tracked state (e.g., position, movement shape, size, or combination thereof) of the kidney stone. The ultrasound imaging transducer(s) is configured to image the stone during the application of the therapy treatment. An optimization algorithm is implemented to control the therapeutic ultrasound transducer to apply different force vectors to the region of the stone. The effect of the vectors in the differing directions with respect to the stone may be detected and input to the optimization algorithm, which optimizes the therapy by adjusting one or more of the vectors.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: November 24, 2020
    Assignee: Otsuka Medical Devices Co., Ltd.
    Inventor: Michael Gertner
  • Patent number: 10828020
    Abstract: A surgical retractor includes a shaft and an end effector extending distally from the shaft. The end effector includes a distal finger extending about at least a portion of a perimeter of a geometric shape and configured to facilitate retraction of tissue. The end effector further includes an ultrasound sensor array including a plurality of ultrasound sensors disposed in spaced-apart relation along the distal finger. Each ultrasound sensor of the plurality of ultrasound sensors is configured to emit an ultrasound wave and receive an echoed wave. The echoed waves received by the plurality of ultrasound sensors are output to be reconstructed to produce a real-time 3D ultrasound video image.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: November 10, 2020
    Assignee: COVIDIEN LP
    Inventor: Matthew S. Cowley
  • Patent number: 10806346
    Abstract: An ultrasound imaging system having real-time tracking and image registration includes a fiducial-marker system comprising an ultrasound transmitter structured to provide a localized ultrasound pulse at an optically observable localized spot on a body of interest. The system further includes an optical imaging system, a two-dimensional ultrasound imaging system, an optical image processing system, and an ultrasound image processing system.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: October 20, 2020
    Assignee: The Johns Hopkins University
    Inventors: Emad M. Boctor, Alexis Cheng, Xiaoyu Guo, Haichong K. Zhang, Russell H. Taylor
  • Patent number: 10772646
    Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.
    Type: Grant
    Filed: May 25, 2019
    Date of Patent: September 15, 2020
    Assignee: Xi'an Jiaotong University
    Inventors: Mingzhu Lu, Yizhe Geng, Ruixin Li, Xuan Wang, Yanshan Liu, Dan Han, Yehui Liu, Yujiao Li, Rui Wang, Mingxi Wan
  • Patent number: 10772655
    Abstract: The invention relates to an interstitial ultrasound ablation device (5) for being inserted into tissue surrounding, for instance, a tumor. The interstitial ultrasound ablation device comprises an arrangement (7) of ultrasound units (17, 18) for a focal ablation treatment which is modifiable from a folded configuration, to be used while inserting the ultrasound ablation device into the tissue, to an unfolded configuration, to be used after the ultrasound ablation device has been inserted into the tissue, such that the unfolded arrangement of ultrasound units is next to the tumor. This ultrasound ablation device can be easily positioned close to the tumor, where the unfolded arrangement of ultrasound units provides a large ultrasound emission area allowing for a very good focusing of the ultrasound on the tumor. This can lead to a very effective ablation of the tumor with only very few or no unwanted side effects.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: September 15, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Debbie Rem-Bronneberg
  • Patent number: 10765410
    Abstract: The present disclosure relates to the field of endoscopy. In particular, the present disclosure relates to systems and methods for real-time visualization of a target tissue, and which allows the location/orientation of the biopsy needle to be determined prior to its first actuation.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: September 8, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Austin G. Johnson, Sean Fleury
  • Patent number: 10758154
    Abstract: A method operates an image system of a medical imaging modality in which a patient data record of a patient is processed. A workflow for an examination is selected from a set of workflows on the basis of an examination specification of the patient data record. Wherein each workflow contains comprises a selection from a set of functions which are carried out in a specific temporal sequence.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: September 1, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Clemens Joerger, Gudrun Roth-Ganter
  • Patent number: 10751125
    Abstract: A focused-ultrasound or other procedure for treating a target within a tissue region can be planned iteratively by creating a treatment plan specifying a treatment location pattern and stimuli applied thereto, simulating the treatment, computationally predicting an effect of the simulated treatment, comparing the predicted effect against one or more treatment constraints (such as efficacy and/or safety thresholds), and, if a constraint is violated, repeating the simulation for an adjusted treatment plan.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: August 25, 2020
    Assignee: INSIGHTEC, LTD.
    Inventors: Yoav Levy, Benny Assif, Gilad Halevy, Yoni Hertzberg
  • Patent number: 10722218
    Abstract: A method of generating a 3-D patient-specific bone model, the method comprising: (a) acquiring a plurality of raw radiofrequency (“RF”) signals from an A-mode ultrasound scan of a patient's bone at a plurality of locations using an ultrasound probe that comprises a transducer array; (b) tracking the acquiring of the plurality of raw RF signals in 3-D space and generating corresponding tracking data; (c) transforming each of the plurality of raw RF signals into an envelope comprising a plurality of peaks by applying an envelope detection algorithm to each of the plurality of raw RF signals, each peak corresponding with a tissue interface echo; (d) identifying a bone echo from the tissue interface echoes of each of the plurality of raw RF signals to comprise a plurality of bone echoes by selecting the last peak having a normalized envelope amplitude above a preset threshold, wherein the envelope amplitude is normalized with respect to a maximum peak existing in the envelope; (e) determining a 2-D bone contour f
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: July 28, 2020
    Assignee: JointVue, LLC
    Inventor: Mohamed R. Mahfouz
  • Patent number: 10722219
    Abstract: Systems and methods are provided for diagnosing neuromuscular disease in a patient suspected of having a neuromuscular disease, Phantoms for use in these systems and methods are also provided. Methods are further provided for determining a normalized ultrasound data value for a patient of interest having a known age, weight, height, and sex.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: July 28, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Andrea J. Boon
  • Patent number: 10722169
    Abstract: A physiological state of a patient is detected by at least producing and detecting pressure waves with a free wall of an implantable medical device (IMD) housing. An actuator element may contact the free wall, e.g., a portion of the IMD housing, and cause movement of the free wall that produces a pressure wave within the fluid and tissue of the patient. A detector element contacting the free wall may in turn detect reflected pressure waves received by the free wall. An acoustic module within the IMD may then determine a physiological condition of the patient, e.g., a bladder fullness state, based on the time delay between the transmitted and reflected pressure waves. In some examples in which the IMD also delivers stimulation therapy to the patient, e.g., incontinence therapy, the IMD may also automatically adjust stimulation therapy based on the determined physiological condition.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: July 28, 2020
    Assignee: Medtronic, Inc.
    Inventors: Richard T. Stone, Xuan Wei
  • Patent number: 10709337
    Abstract: In a photoacoustic measurement apparatus and a photoacoustic measurement system, blood flow information in a desired region can be generated using a photoacoustic image. A light source emits measurement light. A probe detects a photoacoustic wave generated in a subject after measurement light is emitted to the subject in each of the avascularized condition in which the subject is avascularized and the non-avascularized condition in which the subject is not avascularized. Photoacoustic image generation unit generates a photoacoustic image based on the detection signal of the photoacoustic wave. Blood flow information generation unit generates blood flow information based on the signal value of a photoacoustic image in a region of interest set in the photoacoustic image.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: July 14, 2020
    Assignee: FUJIFILM Corporation
    Inventors: Dai Murakoshi, Kaku Irisawa, Tetsuro Ebata, Shoji Hara
  • Patent number: 10695798
    Abstract: The invention relates to a method for calibrating a treatment probe comprising at least one cylindrical transducer for generating high-intensity focused ultrasound in a target focus point, the probe being designed to be electrically connected to a power supply source for supplying an electrical signal for the power supply of the transducer, characterised in that the method comprises a step (20) of adjusting a frequency of the electrical signal for the power supply of the transducer in such a way that the variation between the maximum vibration intensity and the minimum vibration intensity of the transducer along the width thereof is minimal.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: June 30, 2020
    Assignee: EYE TECH CARE
    Inventors: Thomas Charrel, Laure Baffie
  • Patent number: 10675482
    Abstract: An intracranial treatment apparatus comprises an outer shaft having a proximal end and a distal end for positioning within the tissue region of the brain. The outer shaft defines a lumen extending between the proximal end and the distal end of the outer shaft and having at least one aperture adjacent the distal end of the outer shaft. An inner light-delivery element having a distal end and a proximal end is adapted to be operatively connected to the light source. The light-delivery element is configured to be received within the lumen and extend from the proximal end of the shaft to adjacent the distal end of the shaft. The light-delivery element is adapted to deliver light from the light source through the at least one aperture of the outer shaft to the tissue region of the brain in proximity to the distal end of the outer shaft.
    Type: Grant
    Filed: January 2, 2015
    Date of Patent: June 9, 2020
    Assignee: Craniovation, Inc.
    Inventors: Vijay Agarwal, Ranjith Babu, Jack Ratcliffe
  • Patent number: 10668299
    Abstract: A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 2, 2020
    Assignee: Nucletron Operations B.V.
    Inventors: Paulus Cornelis Hendrikus Maria Krechting, Wilhelmus Petrus Martinus Maria Van Erp, Jan F. L. De Becker, Anton J. G. Welberg