Blood Flow Studies Patents (Class 600/454)
  • Patent number: 11963819
    Abstract: A method and system for ultrasonic fluid spectral Doppler imaging are disclosed. The system comprises: a transmission circuit for transmitting an ultrasonic beam to a detection object; a receiving circuit and a beam synthesis module for receiving an echo of the ultrasonic beam and obtaining an ultrasonic echo signal; an image processing module for obtaining an ultrasonic fluid flow state image of a region of interest in the detection object according to the ultrasonic echo signal, identifying a sampling position in the region of interest, respectively obtaining a Doppler spectrogram corresponding to each sampling position according to the ultrasonic echo signal, and generating position displaying marks for characterizing the sampling positions; and a display for displaying the position displaying marks in the ultrasonic fluid flow state image, and displaying the obtained Doppler spectrogram. The system may simultaneously display spectra of multiple locations on a same time axis.
    Type: Grant
    Filed: October 18, 2021
    Date of Patent: April 23, 2024
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Yigang Du, Shuangshuang Li
  • Patent number: 11965959
    Abstract: The present disclosure describes ultrasound systems configured to enhance flow imaging and analysis by adaptively adjusting one or more imaging parameters in response to acquired flow measurements. Example systems can include an ultrasound transducer and one or more processors. Using the system components, mean flow velocity magnitude and acceleration can be determined within a target region during an acquisition phase, which may include a cardiac cycle. One or more adjusted flow imaging parameters, such as adjusted ensemble length, temporal smoothing filter length and/or step size, can be determined based on the acquired flow measurements to increase the signal quality of newly acquired ultrasound echo signals. The adjusted flow imaging parameters can then be applied by the ultrasound transducer during a second acquisition phase.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: April 23, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Shiying Wang, Sheng-Wen Huang, Hua Xie, Keith William Johnson, Liang Zhang, Thanasis Loupas, Truong Huy Nguyen
  • Patent number: 11941754
    Abstract: A three-dimensional geometric model of a heart can be generated from a plurality of two-dimensional image slices of the heart collected using an intracardiac echocardiography (“ICE”) catheter. Each image slice can be associated with localization information for the ICE catheter. The image slices can be output in a plurality of voxels according to their associated localization information, thereby creating a three-dimensional geometric model of the heart. Data sufficiency of the three-dimensional model can also be graphically represented. For example, data sufficiency can be represented using voxel opacity, a one-dimensional illustration, a two-dimensional illustration, and/or a data collection cue.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: March 26, 2024
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Fermin Lupotti, Anthony Wendling, Alexander Gorovoy, Alon Izmirli, Itai Winkler
  • Patent number: 11900593
    Abstract: A method and apparatus for identifying blood vessels in ultrasound images and displaying blood vessels in ultrasound images are described. In some embodiments, the method is implemented by a computing device and includes assigning, with a neural network implemented at least partially in hardware of the computing device, one of a vein classification and an artery classification to one or more blood vessels in ultrasound images. The method also includes determining a misclassification for one blood vessel that denotes the neural network assigning the one of the vein classification and the artery classification to the one blood vessel in one ultrasound image and the other of the vein classification and the artery classification to the one blood vessel in additional ultrasound images. The method includes displaying, in the one ultrasound image, an indication of the other of the vein classification and the artery classification for the one blood vessel.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: February 13, 2024
    Assignee: FUJIFILM SONOSITE, INC.
    Inventors: Davinder S. Dhatt, Christopher Aleksandr White, Adam Benjamin Pely, Thomas Michael Duffy, Paul Tomotaro Danset, Diku Pranav Mandavia
  • Patent number: 11893773
    Abstract: A finger vein comparison method, a computer equipment, and a storage medium are provided. The finger vein comparison method includes: two finger vein images to be compared are obtained (S10); image channel fusion is performed on the two finger vein images to be compared to obtain a two-channel target finger vein image to be compared (S20); the target finger vein image to be compared is input into a feature extractor, and a feature vector of the target finger vein image to be compared is extracted by the feature extractor (S30); the feature vector of the target finger vein image to be compared is input into a dichotomy classifier to obtain a dichotomy result (S40); and it is determined according to the dichotomy result whether the two finger vein images to be compared come from the same finger (S50).
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: February 6, 2024
    Assignee: Ping An Technology (Shenzhen) Co., Ltd.
    Inventors: Zhongdi Chao, Bojin Zhuang, Shaojun Wang
  • Patent number: 11883238
    Abstract: A system for detecting/quantifying the conductance of a right-to-left cardiac shunt includes a mouthpiece assembly, a solenoid-driven vacuum/pressurization assembly; a controller for operating the solenoid-driven vacuum/pressurization assembly; and a monitor for displaying the instructions from the controller. A microbubble counting cell and digital image sensor are combined with software-based image analysis to determine a number of microbubbles contained in a microbubble counting zone. A monitor enables operator specification of total volume of contrast agent to be injected into the patient. One or more first Doppler ultrasound transducer arrays are positioned adjacent to targeted intracranial arteries at one side of the skull or a pair of first Doppler ultrasound transducer arrays positioned adjacent to targeted intracranial arteries at both sides of the skull.
    Type: Grant
    Filed: November 8, 2021
    Date of Patent: January 30, 2024
    Assignee: Eggers & Associates, LLC
    Inventors: Philip E. Eggers, Andrew R. Eggers, David Thomas Dobson
  • Patent number: 11850100
    Abstract: A system and computer-implemented method for detecting flow of biological fluid, and facilitating the diagnosis of stenosis or other pathology of a hepatic artery or other non-carotid vasculature by using machine learning to analyze a spectral Doppler ultrasound waveform of blood flow or flow of other biological fluids. A region of interest is identified in a sonogram, a waveform envelope is generated for a waveform within the region of interest, an extracted waveform is generated based on the waveform envelope, a Fourier transform is performed on the extracted waveform, and a Fourier spectrum is generated. Machine learning is used to determine a likelihood of pathology based on waveform parameters, including the Fourier spectrum, and to determine a pathology prediction value. Additional patient information may be accessed and used in determining the likelihood of the pathology.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: December 26, 2023
    Assignee: The Children's Mercy Hospital
    Inventors: Sherwin S. Chan, Justin Baraboo
  • Patent number: 11839471
    Abstract: In some examples, a system is configured to determine, using a neural network algorithm of a cerebral autoregulation model, a cerebral autoregulation status of the patient based at least in part on a blood pressure of the patient over a period of time and regional cerebral oxygen saturation of the patient over the period of time.
    Type: Grant
    Filed: March 23, 2021
    Date of Patent: December 12, 2023
    Assignee: COVIDIEN LP
    Inventors: Dean Montgomery, Paul S. Addison, Andre Antunes
  • Patent number: 11826107
    Abstract: A registration system for medical navigation includes a shape sensing device (SSD) (104, 504) having at least one sensor (450, 505) for providing corresponding sensor information (SI) indicative of at least one of a position of the at least one sensor (450, 505); a registration fixture (106) having a channel (130) configured to receive at least part of the SSD and defining a registration path (P). The registration fixture may be configured to be attached to a registrant object (RO) (119) defining a workspace. A controller (110) may be configured to: sense a shape of a path traversed by the SSD based upon the SI when the at least one sensor is situated within the channel (130), determine whether the sensed shape of the path corresponds with a known shape selected from one or more known shapes, and perform a coordinate registration based upon the determination.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: November 28, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Paul Thienphrapa, Bharat Ramachandran, Aryeh Leib Reinstein, Douglas Allen Stanton
  • Patent number: 11786212
    Abstract: A method for analysing a structure within a patient's heart includes receiving a patient study including a plurality of images of the patient's heart obtained by an ultrasound device, extracting respective sets of pixel data from the images, and using trained machine learning algorithms to analyse the sets of pixel data to a) identify first images captured using a colour Doppler modality and assign the first images to said structure, b) identify second images captured using spectral Doppler modality and assign the second images to said structure, c) determine a flow convergence zone radius from an analysis of the first images; and d) determine a maximum gradient of structure, from an analysis of the second images. The flow convergence zone radius, the maximum gradient of structure, and a Nyquist value identified for the colour Doppler modality, are combined to determine an Effective Regurgitant Orifice Area for the structure.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: October 17, 2023
    Assignee: UAB Ligence
    Inventors: Karolis {hacek over (S)}ablauskas, Arnas Karu{hacek over (z)}as, Ieva Ka{hacek over (z)}ukauskienē, Antanas Kiziela
  • Patent number: 11701081
    Abstract: A system for visualization and quantification of ultrasound imaging data may include a display unit, and a processor communicatively coupled to the display unit and to an ultrasound imaging apparatus for generating an image from ultrasound data representative of a bodily structure and fluid flowing within the bodily structure. The processor may be configured to generate vector field data corresponding to the fluid flow, wherein the vector field data comprises axial and lateral velocity components of the fluid, extract spatiotemporal information from the vector field data at one or more user-selected points within the image, and cause the display unit to concurrently display the spatiotemporal information at the one or more user-selected points with the image including a graphical representation of the vector field data overlaid on the image, wherein the spatiotemporal information includes at least one of a magnitude and an angle of the fluid flow.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: July 18, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Shiying Wang, Sheng-Wen Huang, Hua Xie, Francois Guy Gerard Marie Vignon, Liang Zhang, Keith William Johnson
  • Patent number: 11666307
    Abstract: Embodiments of the present disclosure are configured to assess effectiveness of an endovascular aneurysm coiling procedure. A system is provided that can include a flow-sensing intravascular device with a flexible elongate member which is sized and shaped for insertion into a vasculature, and a flow sensing element secured to a distal portion of the flexible elongate member. A computer can be in communication with the flow-sensing intravascular device. With a coil is positioned within an aneurysm, the computer can detect a flow measurement of fluid entering the aneurysm based on data obtained by the flow sensing element positioned within the aneurysm, and can determine that the fluid flow measurement is at or below an acceptable level. If flow is at an unacceptable level, additional coils can be added to further restrict flow. Also, a second source of fluid into the aneurysm can be indicated by the flow measurements.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: June 6, 2023
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventor: John Unser
  • Patent number: 11650314
    Abstract: Provided are a method of displaying a Doppler image and an ultrasound diagnosis apparatus for performing the method. The method includes: obtaining a first Doppler signal where clutter filtering corresponding to each of a plurality of pixels is not performed and a second Doppler signal where clutter filtering corresponding to each of the plurality of pixels is performed; determining a first motion score indicating a degree of flash artifact occurrence by using velocity information of the first Doppler signal; determining a first weight for suppressing flash artifacts of each pixel based on the first motion score and a velocity difference value between the first Doppler signal and the second Doppler signal; generating a first Doppler image of the object by applying the first weight to the second Doppler signal of each pixel; and displaying the first Doppler image of the object.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: May 16, 2023
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventors: Yujin Lee, Jaekeun Lee, Hojin Ryoo
  • Patent number: 11633120
    Abstract: Systems and methods for performing and assessing neuromodulation therapy are disclosed herein. One method for assessing the efficacy of neuromodulation therapy includes positioning a neuromodulation catheter at a target site within a renal blood vessel of a human patient and delivering neuromodulation energy at the target site with the neuromodulation catheter. The method can further include obtaining a measurement related to a blood flow rate through the renal blood vessel via the neuromodulation catheter. The measurement can be compared to a baseline measurement related to the blood flow rate through the renal blood vessel to assess the efficacy of the neuromodulation therapy. In some embodiments, the baseline and post-neuromodulation measurements are obtained by injecting an indicator fluid into the renal blood vessel upstream of the target site and detecting a transient change in vessel impedance caused by the indicator fluid.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: April 25, 2023
    Assignee: MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
    Inventors: Douglas Hettrick, Paul Coates
  • Patent number: 11617560
    Abstract: The present invention aims at improving the Doppler imaging of a biological sample comprising blood. For this, it is proposed a method for imaging a biological sample (10), the sample (10) comprising blood (14) comprising diffusors and solid tissue (16), the method comprising obtaining observation, each observation being characterized by a different point spread function associating a signal to each location of the region of interest, the signal comprising a first contribution representative of the diffusors of blood vessels within the location, a second contribution representative of the tissue diffusors and a third contribution representative of blood signal associated to blood diffusors outside of the location, and estimating, for each location, the blood flow by using a statistical analysis.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: April 4, 2023
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIME INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PARIS CITÉ, SORBONNE UNIVERSITÉ
    Inventors: Zsolt Lenkei, Mathieu Pernot, Mickael Tanter, Thomas Deffieux
  • Patent number: 11602324
    Abstract: Embodiments of the present disclosure provide a flow imaging processing method, which may include determining flow imaging parameters, where the flow imaging parameters include a sound speed for calculation, a center frequency of the transmitting pulse for exciting a probe and a imaging depth; obtaining a velocity measurement range; and determining the first target number of the different transmit angles according to the sound speed for calculation, the center frequency of the transmitting pulse, the imaging depth and the velocity measurement range. The embodiments of the present disclosure also provide an ultrasound imaging device.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: March 14, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Yigang Du, Wei Fan, Lanxi Xiang, Yuan Wang, Yingying Shen, Kai Wang, Donghai Qin
  • Patent number: 11596380
    Abstract: Arrangements described herein relate to systems, apparatuses, and methods for categorizing a waveform that includes processing a signal containing ultrasound data about the waveform, identifying one or more morphological variables of the waveform based on the ultrasound data, identifying one or more categories that correspond to a range of combinations of the morphological variables, and categorizing the waveform as belonging to one of the one or more categories. In some arrangements, the method may further include visualizing the waveforms, determining a probability that the waveform belongs to each of the one or more categories, and/or displaying the probability that the waveform falls into each of the one or more categories. Morphological variables may include quantifying absolute peak onset, number/prominence of auxiliary peaks, and systolic canopy length.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: March 7, 2023
    Assignee: NovaSignal Corp.
    Inventors: Samuel G. Thorpe, Corey M. Thibeault, Nicolas Canac, Kian Jalaleddini
  • Patent number: 11583194
    Abstract: The present invention provides a non-invasive portable device and method for diagnosing an occlusion in coronary arteries of a patient. The diagnostic system includes a signal processor configured to receive signals from a group of acoustic sensors attached to the torso of a patient. The diagnostic device is configured with a processor to receive and generate an output on a display using a high end algorithm.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: February 21, 2023
    Inventors: Hemchandra Madhusudan Shertukde, Rekha Hemchandra Shertukde
  • Patent number: 11576652
    Abstract: Intravascular ultrasound (IVUS) imaging devices, systems, and method are provided. In one embodiment, an IVUS imaging device includes a flexible elongate member configured to be positioned within a lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion; and an imaging assembly disposed at the distal portion of the flexible elongate member. The imaging assembly includes a first ultrasound transducer operating at a first center frequency; and a second ultrasound transducer operating at a second center frequency different from the first center frequency.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: February 14, 2023
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Dino De Cicco, Eric Khairy, David Goodman
  • Patent number: 11564582
    Abstract: A monitoring system includes an implantable intra-vascular support device for positioning against a vessel wall and an implantable sensor-actuator mounted to the support device. The sensor-actuator is drivable between a non-deployed position in which it is against the support device and a deployed position in which it is displaced away from the support device. Sensor signals are generated when in the deployed position. This system is able to monitor flow away from the edge of a vessel by deploying the sensor-actuator towards the center of the vessel. When flow monitoring does not need to take place, it can be non-deployed so that it does not present an occlusion to the flow.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: January 31, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Cornelis Petrus Hendriks, Mark Thomas Johnson, Achim Rudolf Hilgers, Franciscus Johannes Gerardus Hakkens, Daan Anton Van Den Ende, Manfred Müller, Arjen Van Der Horst
  • Patent number: 11559283
    Abstract: An ultrasound diagnosis apparatus including: an ultrasound probe having a transducer array; and a processor configured to: perform transmission and reception of an ultrasonic beam from the transducer array toward a subject, into which contrast media including microbubbles is introduced; image a reception signal output from the transducer array to generate an ultrasound image of the subject; acquire trajectories of the microbubbles in a one cross section of the subject by tracking movement of the microbubbles based on the ultrasound image corresponding to the one cross section of the subject; detect, as a feature point, a trajectory, in which a distance between a start point and an end point in a prescribed time range is less than a prescribed value, among the trajectories of the microbubbles; and display the ultrasound image, the acquired trajectories and the detected feature point on the display unit.
    Type: Grant
    Filed: March 20, 2020
    Date of Patent: January 24, 2023
    Assignee: FUJIFILM Corporation
    Inventors: Hiroaki Yamamoto, Tomoki Inoue
  • Patent number: 11547384
    Abstract: Ultrasound methods provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously). Ultrasound systems provide for the motion tracking of both vessel wall motion and blood flow (e.g., with use of high frame rate ultrasound pulse echo data and speckle tracking both wall motion and flow can be tracked simultaneously).
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: January 10, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Emad S. Ebbini, Dalong Liu, Yayun Wan, Andrew J. Casper
  • Patent number: 11510653
    Abstract: To uniformly extract a secondary flow based on quantitative calculation even in a complicated blood flow in a heart chamber or a blood vessel.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: November 29, 2022
    Assignee: FUJIFILM Healthcare Corporation
    Inventors: Motochika Shimizu, Takashi Okada, Tomohide Nishiyama
  • Patent number: 11510630
    Abstract: The present invention provides an image display method with which a structure of an imaging object can be easily understood on the basis of volume data. An image display method according to an aspect of the present invention includes obtaining photoacoustic image data, generating a first photoacoustic image corresponding to a first spatial region on the basis of photoacoustic image data and a second photoacoustic image corresponding to a second spatial region having a different thickness in a viewing direction of rendering from a thickness of the first spatial region and having a spatial region overlapped with the first spatial region on the basis of the photoacoustic image data, and generating and displaying a parallel image in which the first photoacoustic image and the second photoacoustic image are arranged side by side.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 29, 2022
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Satoru Fukushima, Hiroshi Abe
  • Patent number: 11426145
    Abstract: To correctly trace a target component even when a folded component is included in a Doppler waveform. The Doppler waveform is configured by a plurality of luminance distributions 54 arranged on a time axis. In each luminance distribution 54, a minimum luminance value located in the trough portion 54c between the target portion 54a and the folded portion 54b is specified. A search start point Pn is set based on the minimum luminance value. A trace point 60 is specified by searching from the search start point Pn to a base line 61 side.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: August 30, 2022
    Assignee: FUJIFILM HEALTHCARE CORPORATION
    Inventors: Seiji Oyama, Kazumasa Ise
  • Patent number: 11417305
    Abstract: An hourglass transducer including a longitudinal driver, a shell, and a pair of endcaps is provided. The driver drives the transducer. The pair of endcaps is attached to ends of the driver and cap the shell enclosing the transducer. The shell includes a first shell end, a second shell end, and a pleated geometry. The first shell end and second shell end are structured with circular cross sections. The pleated geometry is between the first shell end and the second shell end. A perimeter of the pleated geometry is the same as perimeters of the circular cross sections of the first shell end and the second shell end.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: August 16, 2022
    Assignee: Raytheon Company
    Inventors: Patrick M. Brogan, Daniel Brogan, John C. Cochran
  • Patent number: 11413019
    Abstract: Provided is an ultrasound imaging apparatus comprising: an image processing unit for connecting relevant blood flows and classifying the same into a plurality of blood flow trees on the basis of information on blood flow direction and blood flow velocity obtained from morphological information of a target object and three-dimensional blood flow data; a user input unit for receiving a user input which selects a blood flow tree, in which a target blood flow is included, from among the plurality of blood flow trees; and a display unit for displaying the selected blood flow tree on a three-dimensional rendering image on the basis of the user input.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: August 16, 2022
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventors: Han-jun Kim, Sung-yoon Kim, Jong-sik Kim
  • Patent number: 11386998
    Abstract: Disclosed herein are embodiments of systems and techniques for estimating the severity of chronic obstructive pulmonary disease (COPD) in a patient. For example, in some embodiments, a system for estimating COPD severity in a patient may include logic to receive a breathing signal representative of breathing activity of the patient over a time interval, receive a locomotion signal representative of locomotive activity of the patient over the time interval, and provide breathing data and locomotion data to additional logic, wherein the additional logic is to generate an estimate of COPD severity in the patient by comparison of 1) a cross-recurrence quantification analysis (cRQA) parameter between the breathing data and the locomotion data and 2) a reference value. The breathing data may be based on the breathing signal, and the locomotion data may be based on the locomotion signal.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: July 12, 2022
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Nicholas Stergiou, Jennifer Yentes, Stephen I. Rennard, Amol Patil, William Denton
  • Patent number: 11357447
    Abstract: The present invention, in some embodiments thereof, relates to methods and/or apparatus for measuring the effectiveness of a renal denervation treatment. In some embodiments, a method for determining effectiveness of the denervation treatment comprises tracking at least one of arterial wall movement, arterial blood flow rate, arterial blood flow velocity, blood pressure and arterial diameter at one or more selected locations in the renal artery over time, and assessing the effectiveness of said renal denervation treatment according to results obtained by tracking.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: June 14, 2022
    Assignee: Sonivie Ltd.
    Inventors: Ariel Sverdlik, Benny Dilmoney, Yehuda Zadok, Or Shabtay
  • Patent number: 11337673
    Abstract: A system for boundary identification includes a memory (42) to store shear wave displacements through a medium as a displacement field including a spatial component and a temporal component. A directional filter (206, 208) filters the displacement field to provide a directional displacement field. A signal processing device (26) is coupled to the memory to execute a boundary estimator (214) to estimate a tissue boundary in a displayed image based upon a history of the directional displacement field accumulated over time.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: May 24, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Faik Can Meral, Shriram Sethuraman, Pingkun Yan, William Tao Shi, Jochen Kruecker
  • Patent number: 11311456
    Abstract: A system for assisting with a cardiopulmonary resuscitation (CPR) treatment being administered to a patient. In one aspect, a system for assisting with a cardiopulmonary resuscitation (CPR) treatment being administered to a patient includes a sensor for determining a parameter of the patient (e.g., indicative of a blood flow or pressure waveform), and one or more processors configured for receiving input from the sensor, determining, based on the input from the sensor, whether a rate of chest compressions administered in the CPR treatment should be changed, and providing an indication to a user that the rate of chest compressions should be changed.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: April 26, 2022
    Assignee: ZOLL Medical Corporation
    Inventors: Christopher Luke Kaufman, Gary A. Freeman, Ulrich Herken
  • Patent number: 11315690
    Abstract: A computer-implemented method for simulating blood flow through one or more coronary blood vessels may first involve receiving patient-specific data, including imaging data related to one or more coronary blood vessels, and at least one clinically measured flow parameter. Next, the method may involve generating a digital model of the one or more coronary blood vessels, based at least partially on the imaging data, discretizing the model, applying boundary conditions to a portion of the digital model that contains the one or more coronary blood vessels, and initializing and solving mathematical equations of blood flow through the model to generate computerized flow parameters. Finally, the method may involve comparing the computerized flow parameters with the at least one clinically measured flow parameter.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: April 26, 2022
    Assignee: Stenomics, Inc.
    Inventor: Michael A. Singer
  • Patent number: 11229418
    Abstract: An aspect of the present disclosure is to provide a device or needle placement system including a needle having a proximal end and a distal end, and an ultrasound transducer element attached to the distal end of the needle. The system also includes a needle constraining assembly configured to receive and constrain the needle to only rotational degrees of freedom within a range of angular motion. The system further includes a needle sensor system incorporated into the constraining assembly to sense an angular orientation of the needle with the range of angular motion. The system also includes an ultrasound data processor configured to communicate with the transducer element to receive ultrasound detection signals and communicate with the needle sensor system to receive needle angular orientation signals. Based on the ultrasound detection and the needle angular orientation signals, the ultrasound data processor can calculate synthetic aperture ultrasound images.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: January 25, 2022
    Assignee: The Johns Hopkins University
    Inventors: Nisu Patel, Ernest Scalabrin, Karun Kannan, Kush Gupta, Larissa Chan, Mateo Paredes, Melissa Lin, Shayan Roychoudhury, Suraj Shah, Abhay Moghekar, Emad M. Boctor, Nicholas J. Durr, Younsu Kim, Haichong K. Zhang
  • Patent number: 11213257
    Abstract: The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: January 4, 2022
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventor: Glen W. McLaughlin
  • Patent number: 11177022
    Abstract: Workflows for automatic measurement of Doppler is provided. In various embodiments, a plurality of frames of a medical video are read. A mode label indicative of a mode of each of the plurality of frames is determined. At least one of the plurality of frames is provided to a trained feature generator. The at least one of the plurality of frames have the same mode label. At least one feature vector is obtained from the trained feature generator corresponding to the at least one of the plurality of frames. At least one feature vector is provided to a trained classifier. A valve label indicative of a valve is obtained from the trained classifier corresponding to the at least one of the plurality of frames. One or more measurement is extracted indicative of a disease condition from those of the at least one of the plurality of frames matching a predetermined valve label.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: November 16, 2021
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Colin Compas, Yaniv Gur, Mehdi Moradi, Mohammadreza Negahdar, Tanveer Syeda-Mahmood
  • Patent number: 11160513
    Abstract: Devices, systems, and methods directed to evaluating a vessel of a patient are provided. The method includes outputting, to a display, a screen display including: a visual representation of a pressure ratio of pressure measurements obtained by first and second instruments positioned within a vessel while the second instrument is moved longitudinally through the vessel and the first instrument remains stationary within the vessel; and a visual representation of the vessel; receiving a user input to modify one of the visual representations of the pressure ratio and the vessel to simulate a therapeutic procedure; and updating the screen display, in response to the user input, including: modifying the selected one of the visual representation of the pressure ratio and the vessel based on the received user input; and correspondingly modifying the unselected one of the visual representation of the pressure ratio and the vessel.
    Type: Grant
    Filed: February 23, 2020
    Date of Patent: November 2, 2021
    Assignee: KONINKLIJIKE PHILIPS N.V.
    Inventors: David Anderson, Andrew Tochterman
  • Patent number: 11157527
    Abstract: A system may receive a sensor dataset representing an environment and use the dataset to create or update a map. In creating or updating the map, the system may determine an object classification of one or more detected objects and only selectively incorporate data into the map based at least in part on the classification. The map may be associated with the classification (or semantic) information of the objects, as well as weights based on the classification. Similarly, datasets with selected classes of data removed may be used for system localization. Further, the system may determine an object track of the objects. When updating the map, voxels in a voxel space may indicate an occupied voxel based on a threshold number of observances. The object track and clean map can then be used for controlling an autonomous vehicle.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: October 26, 2021
    Assignee: Zoox, Inc.
    Inventors: Zeng Wang, Nitesh Shroff, Dragomir Dimitrov Anguelov, Subhasis Das, Jesse Sol Levinson, Brice Rebsamen
  • Patent number: 11141063
    Abstract: Provided herein are systems, methods and apparatuses for an integrated system and architectures comprising a central processing unit (CPU) located a substantial physical distance from a sample.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: October 12, 2021
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Nathaniel J. Kemp, Timothy K. Glynn
  • Patent number: 11109841
    Abstract: A system and method for simultaneously presenting Doppler signals of a Multi-Gated Doppler (MGD) signal corresponding to different anatomical structures is provided. The method includes receiving an MGD signal having a plurality of Doppler signals. The method includes analyzing the MGD signal to select multiple gates, each of the gates corresponding with a Doppler signal, and each of the selected gates associated with a different anatomical structure. The method includes selecting a set of parameters for each of the selected gates and applying each selected set of parameters for each of the selected gates. The selected set of parameters for each of the selected gates may be one or both of image acquisition parameters or display processing parameters. The method includes simultaneously presenting the Doppler signal for each of the selected gates at a display system after the each selected set of parameters is applied.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: September 7, 2021
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Alexander Sokulin, Menachem Halmann, Cynthia A. Owen, Dani Pinkovich
  • Patent number: 11109766
    Abstract: This disclosure provides systems and methods for measuring fluid flow in a vasculature system of a patient. Some systems may include an injection system configured to inject a bolus of fluid into a vessel of a patient. Some systems may include a measurement engine configured to monitor the bolus of fluid in the vessel using measurement data generated by an intravascular measuring device. The measurement engine may determine a travel distance of the bolus of fluid and an elapsed time during which the bolus of fluid traversed the travel distance based on the measurement data. A fluid flow rate (e.g., velocity, volumetric flow) of the vessel may be calculated using the travel distance and the elapsed time.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: September 7, 2021
    Assignee: ACIST Medical Systems, Inc.
    Inventors: Robert F. Wilson, Edward R. Miller, Sidney Donald Nystrom, Kendall R. Waters
  • Patent number: 11096669
    Abstract: An ultrasound diagnostic apparatus includes a transmitter, a receiver and a hardware processor. The transmitter outputs a drive signal for a C-mode image to an ultrasound probe. The receiver obtains a reception signal from the probe. The processor sets at least one mask in a frame of packet data of the reception signal; calculates a covariance matrix from a plurality of packet data included in the mask; calculates an eigenvector for the mask from the covariance matrix; calculates a first filter coefficient for the packet data by using the eigenvector and a gain matrix; performs interpolation on the first filter coefficient to calculate a second filter coefficient for packet data of each position in the frame; filters the packet data of the position by using the second filter coefficient; and generates C-mode image data from the filtered packet data.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: August 24, 2021
    Assignee: KONICA MINOLTA, INC.
    Inventor: Yoshihiro Takeda
  • Patent number: 11064964
    Abstract: Apparatus and methods are described for use with a plurality of angiographic image frames of a moving lumen of a subject, including aligning the image frames with each other. Using the aligned image frames, a time it takes a contrast agent to travel a known distance through the lumen is determined. At least partially in response thereto, a characteristic of the lumen is determined, and, in response to the determined characteristic, an output is generated on a display. Other applications are also described.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: July 20, 2021
    Assignee: SYNC-RX, LTD
    Inventors: David Tolkowsky, Alexander Steinberg, Eldad Klaiman, Ran Cohen
  • Patent number: 11020085
    Abstract: A spectral Doppler processor for an ultrasound system produces blood flow velocity estimates by processing a sequence of complex blood flow echo samples with an FFT algorithm. The FFT algorithm is executed with a long window of samples to produce velocity estimates with good velocity precision and is executed with a short window of samples to produce velocity estimates with good time precision. The long window algorithm is used when blood flow velocity is not changing rapidly, and the short window algorithm is used when blood flow velocity is changing rapidly.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: June 1, 2021
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: David Wesley Clark
  • Patent number: 11020095
    Abstract: Cardiac monitoring is implemented by transmitting ultrasound energy into a lung of the subject, receiving ultrasound reflections, detecting Doppler shifts in the received reflections, and processing the Doppler shifts into power and velocity data. A plurality of cardiac cycles are identified within the power and velocity data, and a plurality of features corresponding to each of the plurality of cardiac cycles are identified. The identified features are characterized into a set of parameters, and the set of parameters is transmitted to a remote location. The set of parameters is analyzed at the remote location to determine if an abnormality exists. If an abnormality exists, an indication is output from the remote location.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: June 1, 2021
    Assignee: Echosense Jersey Limited
    Inventor: Yoram Palti
  • Patent number: 11006839
    Abstract: A biometric information sensor includes a flexible substrate, an adhesive, a heartbeat signal detector, an electrocardiographic signal detector, a pulse wave detector, and a signal processor. The signal processor calculates an electrocardiographic peak estimated value resulting from estimating the wave of an electrocardiographic signal detected by the electrocardiographic signal detector from a heartbeat signal detected by the heartbeat signal detector based on the heartbeat signal and the electrocardiographic signal. The signal processor estimates a pulse wave transmit time based on the calculated electrocardiographic peak estimated value a photoplethysmographic signal detected by the pulse wave detector.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: May 18, 2021
    Assignee: MURATA MANUFACTURING CO., LTD.
    Inventors: Hirofumi Tsuchimoto, Kengo Saito
  • Patent number: 10987010
    Abstract: Systems and methods are disclosed for diagnosing and treatment planning for vascular steal syndromes and retrograde flow. One method includes receiving a reference blood flow direction at a location in a reference vasculature; determining a patient-related blood flow direction at a location in a patient's vasculature corresponding to the location in the reference vasculature; determining a difference in direction, between the reference blood flow direction of the reference vasculature and the patient-related blood flow direction of the patient's vasculature; and generating a representation of the location in the patient's vasculature associated with the difference in direction between the reference blood flow direction and the patient-related blood flow direction, or generating a treatment recommendation for the patient's vasculature based on the difference in direction between the reference blood flow direction and the patient-related blood flow direction.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: April 27, 2021
    Assignee: HeartFlow, Inc.
    Inventors: Leo J. Grady, Charles A. Taylor
  • Patent number: 10978202
    Abstract: A system, computer program product and method for facilitating concurrent monitoring of multiple obstetrics patients over a data network are proposed. Data conveying pregnancy progression information, including maternal and fetal vital sign information associated with the obstetrics patients, is received and processed to derive criticality levels for the obstetrics patients. As a first feature, notification data related to a particular obstetrics patient may be selectively transmitted to a medical expert based on different conditions including for example an associated criticality level exceeding a threshold and/or receipt of a consultation request. As a second feature, used together or separately from the first, a graphical user interface (GUI) may present a user with an ordered list of obstetrics patients dynamically adaptable based on the criticality levels.
    Type: Grant
    Filed: April 21, 2016
    Date of Patent: April 13, 2021
    Assignee: PERIGEN INC.
    Inventors: Emily Hamilton, Bruno Bendavid
  • Patent number: 10928494
    Abstract: Disclosed is a single ultrasound imaging probe 101 comprising a single ultrasound transducer array 103 comprising a first array segment 201 comprising a K plurality of ultrasound transducer elements 103a and an orthogonally arranged second array segment 202 comprising an M plurality of ultrasound transducer elements 103b such that the first array segment 201 and the second array segment 202 comprise a K plurality of ultrasound transducer elements 103a plus an M plurality of ultrasound transducer elements 103b which are electrically connected to provide for the simultaneous display of a scan-converted transverse view ultrasound image and of a scan-converted longitudinal view ultrasound image in a video display 406 of a target scan region for three-dimensional alignment, guided by a projected light beam, of an exterior device in order to access an interior structure below the exterior target region.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: February 23, 2021
    Inventors: Roman Solek, Albert Lee, David Asarnow
  • Patent number: 10918354
    Abstract: A medical device for providing guidance to administered cardiopulmonary resuscitation during cardiac arrest in a subject comprising a measuring probe to measure a hemodynamic property of blood flowing through a blood vessel of the subject, an interface element with reference indicia to guide the measuring probe to major blood vessels of the subject experiencing cardiac arrest, and a blood flow monitoring device comprising a data module to collect measured hemodynamic properties of the subject and a guidance module configured to display resuscitation guidance information for manipulating at least one hemodynamic property of the blood.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: February 16, 2021
    Assignee: UNIVERSITY OF WASHINGTON
    Inventors: Graham Nichol, Adeyinka Adedipe, Pierre D. Mourad
  • Patent number: 10912538
    Abstract: An ultrasound diagnostic apparatus includes an ultrasound image producer which produces an ultrasound image from reception data based on a predetermined set sound speed, a reception data image producer which produces a reception data image representing a luminance image of an ultrasonic echo wavefront from the reception data corresponding to a predetermined range on at least one scan line in the ultrasound image, a sound speed determination unit configured to determine an optimum sound speed based on ultrasound images respectively produced by the ultrasound image producer while changing the predetermined set sound speed, and a controller which makes an ultrasound image for diagnosis produced by the ultrasound image producer and the reception data image produced by the reception data image producer be displayed simultaneously on a display unit based on the optimum sound speed determined by the sound speed determination unit.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: February 9, 2021
    Assignee: FUJIFILM Corporation
    Inventor: Toshitaka Agano