Detecting Brain Electric Signal Patents (Class 600/544)
  • Patent number: 10349888
    Abstract: The invention provided herein relates to a wearable medical device and methods of use thereof for monitoring brain signals by electroencephalography technology in critically ill subjects suspected of having abnormal brain wave patterns including but not limited to electrographic seizures, spike and waves, periodic discharges and rhythmic delta activity.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: July 16, 2019
    Inventor: Carlos Federico Muniz
  • Patent number: 10342475
    Abstract: In a threshold estimation apparatus, a setting unit sets an initial intensity value for each electrode. A selection unit randomly selects an electrode. A stimulation unit, via the selected electrode, stimulates a living subject at an intensity set for the electrode. A detection unit detects the presence or absence of a response evoked by the stimulation. An update unit reduces or increases the intensity associated with the selected electrode, based on the presence or absence of the response evoked by the stimulation. An estimation unit, if the thus updated intensity associated with each electrode satisfies a convergence condition, estimates a convergence value as a threshold associated with the electrode. The threshold estimation apparatus repeats these processes until thresholds associated with all electrodes are estimated. If the same electrode was consecutively selected, the time interval between a stimulation and a subsequent stimulation is adjusted.
    Type: Grant
    Filed: August 7, 2015
    Date of Patent: July 9, 2019
    Assignee: RIKEN
    Inventors: Atsushi Iriki, Junichi Ushiba, Mitsuaki Takemi
  • Patent number: 10342447
    Abstract: System and method for non-contact acquisition of current physiological data representing a subject. A first electromagnetic wave representing current physiological status of a first subject is modified by a second electromagnetic wave representing current physiological status of a second subject in proximity to the first subject. A parameter of the first electromagnetic wave representing a first physiological status of a first subject is measured with electronic circuitry to extract a parameter of the second electromagnetic wave. Historical physiological data associated with the second subject is acquired. The current physiological data representing current physiological status of the second subject is then derived based on historical physiological data of the second subject and a comparison between the first and second parameters.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: July 9, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Ayan Banerjee, Sandeep K. S. Gupta, Priyanka Bagade
  • Patent number: 10327715
    Abstract: Provided is a device for detecting stress of a user based on a bio-signal of the user, and when the stress is detected, outputting information of a peripheral device.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: June 25, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Ji-seon Won, Yong Kim, Jing-sung Kim, Hwa-kyung Kim, Jong-youb Ryu, Kyoung-jin Moon, Chang-hyun Lee, Yong-hyun Lim, Hae-in Chun
  • Patent number: 10322285
    Abstract: This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: June 18, 2019
    Assignee: CLEVELAND CLINIC FOUNDATION
    Inventors: Cameron C. McIntyre, Christopher R. Butson, John D. Hall, Jaimie M. Henderson
  • Patent number: 10318833
    Abstract: The present invention relates a novel system and method for person identification and personality assessment based on electroencephalography (EEG) signal. More particularly, this invention relates to a novel method of EEG recording and processing to map the inherent and unique properties of brain in the form of highly specific brain signature to be used as means for person identification and personality assessment.
    Type: Grant
    Filed: January 18, 2016
    Date of Patent: June 11, 2019
    Inventors: Puneet Agarwal, Siddharth Panwar
  • Patent number: 10311744
    Abstract: A cognitive training method has a step of obtaining sensor data of a subject during a memory exercise which in turn determines whether the sensor data includes predetermined information indicative of cognitive functions used for remembering. The step of advancing the memory exercise is carried out when it is determined that the sensor data includes predetermined information indicative of cognitive functions used for remembering. The step of calculating an objective cognitive assessment of the subject is carried out when the memory exercise is completed and cognitive training is measured at least partially in response to the advancing of the memory exercise. The fact that an objective cognitive assessment is calculated provides a method of using an autodidactic cognitive training device.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: June 4, 2019
    Assignees: Agency for Science, Technology and Research, National University of Singapore
    Inventors: Hai Hong Zhang, Cuntai Guan, Ranga Krishnan, Tih Shih Lee, Zheng Yang Chin, Chuan Chu Wang
  • Patent number: 10299695
    Abstract: Methods and systems for evaluating a subject's response to a task related to a stimulus include a brain activity sensor, such as an EEG sensor, for measuring neural data generated by the subject in response to the visual stimulus. One or more neural discriminators can be calculated based on the neural data. In order to generate one or more neural discriminators, two or more task conditions can be selected for discrimination. The subject's performance can be evaluated based on the one or more neural discriminators. Feedback can be provided to the subject to assist in achieving better performance.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: May 28, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Jordan Muraskin, Jason Sherwin, Paul Sajda
  • Patent number: 10292640
    Abstract: A method for evaluating pain experienced by a human is disclosed. The method includes applying a first noxious stimulus to a normative site on the human, wherein the first noxious stimulus is applied below a pain threshold of the human and logging a first information associated with the first noxious stimulus. The method further includes applying a second noxious stimulus to a source of the pain in the human, wherein the second noxious stimulus is applied until pain threshold is reached and logging a second information associated with the second noxious stimulus. The method further includes increasing the second noxious stimulus until pain tolerance is reached and logging a third information associated with the second noxious stimulus. The method further includes continuing to apply the second noxious stimulus until the human can no longer tolerate the second noxious stimulus and logging a fourth information associated with the second noxious stimulus.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: May 21, 2019
    Inventor: David B. Ross
  • Patent number: 10285615
    Abstract: A personal wearable EEG monitor (1) is adapted to be carried at the head of a person. The EEG monitor comprises an EEG sensor part having skin surface electrodes (3) for measuring EEG signals from said person. The EEG monitor comprises an EEG signal analyzer (5, 5?) adapted for monitoring and analyzing the EEG signal. The EEG monitor (1) performs at least one of the following: providing a stimulus to the person, requesting the person to perform a stimuli creating act, or identifying a stimuli creating ambient sound. The EEG monitor comprises means for identifying an induced response from the EEG signal caused by the stimuli, and a classifier for deciding whether the skin surface electrodes receive EEG signals. The invention further provides a method of monitoring EEG signals of a person.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: May 14, 2019
    Assignee: WIDEX A/S
    Inventors: Preben Kidmose, Michael Ungstrup, Mike Lind Rank
  • Patent number: 10291977
    Abstract: A method and system for detecting bioelectrical signals and audio signals from a user, including establishing bioelectrical contact between a user and one or more sensors of a biomonitoring neuroheadset; collecting, at the one or more sensors, one or more bioelectrical signal datasets; collecting one or more reference signal datasets; collecting, at a microphone of the biomonitoring neuroheadset, an audio signal dataset; and generating a combined audio and bioelectrical signal processed dataset, including producing a noise-reduced bioelectrical signal dataset, and producing a conditioned audio signal dataset.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: May 14, 2019
    Assignee: Emotiv Inc.
    Inventors: Geoffrey Mackellar, Tan Le
  • Patent number: 10275500
    Abstract: Data processing including a universal metric to quantify and estimate the similarity and dissimilarity between data sets. Data streams are perfectly annihilated by a correct realization of their anti-streams. Any deviation of the collision product from a baseline, for example flat white noise, quantifies statistical dissimilarity. The invention relates generally to data mining. More specifically, the invention relates to the analysis of data using a universal metric to quantify and estimate the similarity and dissimilarity between sets of data.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: April 30, 2019
    Assignee: Cornell University
    Inventors: Ishanu Chattopadhyay, Hod Lipson
  • Patent number: 10275487
    Abstract: A first question may be received. A first tag may be identified. The first tag may correspond to a first demographic trait. The first tag may be for use in providing a context for generating a first answer estimate to the first question. The first answer estimate may be generated using natural language processing and based on the first tag.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: April 30, 2019
    Assignee: International Business Machines Corporation
    Inventors: Anthony W. Eichenlaub, Cynthia M. Murch, Terrence T. Nixa, Jan M. Nordland, John E. Petri, Michelle A. Schlicht
  • Patent number: 10258798
    Abstract: A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: April 16, 2019
    Assignee: Medtronic, Inc.
    Inventors: Eric J. Panken, Timothy J. Denison, Gregory F. Molnar
  • Patent number: 10226198
    Abstract: An electrode attachment state determination system includes: an electroencephalogram measurement section for measuring an electroencephalogram signal of a user by using at least one set of electrodes including a ground electrode, a reference electrode, and a measurement electrode; a frequency analysis section for performing a frequency analysis of the electroencephalogram signal; an insufficient electrode determination section for extracting at least one parameter of a total frequency power and a noise amount from a result of the frequency analysis, and through a comparison of a value of the parameter against a predetermined threshold value, determining whether the ground electrode, the reference electrode, or the measurement electrode has an insufficient state of attachment; and an output section for, when an insufficient state of attachment is determined, presenting information indicating the insufficient state of electrode attachment to the user.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: March 12, 2019
    Assignee: Panasonic Intellectual Property Management Co., Ltd.
    Inventors: Yoshihisa Terada, Koji Morikawa
  • Patent number: 10210611
    Abstract: An image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to obtain a value of an index related to a predetermined disease for each of a plurality of sites included in a brain of a patient, on the basis of a plurality of pieces of medical image data obtained by imaging the brain of the patient at each of a plurality of points in time. The processing circuitry is configured to analyze, for each of the plurality of sites, a relationship between changes in the value at the plurality of points in time and a progress model indicating changes in the index through progress of the predetermined disease. The processing circuitry is configured to output an analysis result obtained from the analysis for each of the plurality of sites.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: February 19, 2019
    Assignee: Toshiba Medical Systems Corporation
    Inventors: Ryo Shiroishi, Tomohiro Kawasaki, Yasuko Fujisawa
  • Patent number: 10204389
    Abstract: A computer-implemented method for providing summary information for lifesaving activities is disclosed.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: February 12, 2019
    Assignee: ZOLL MEDICAL CORPORATION
    Inventors: Richard A. Packer, Gary A. Freeman, Annemarie Silver
  • Patent number: 10194865
    Abstract: A system for detecting bioelectrical signals of a user comprising: a set of sensors configured to detect bioelectrical signals from the user, each sensor in the set of sensors configured to provide non-polarizable contact at the body of the user; an electronics subsystem comprising a power module configured to distribute power to the system and a signal processing module configured to receive signals from the set of sensors; a set of sensor interfaces coupling the set of sensors to the electronics subsystem and configured to facilitate noise isolation within the system; and a housing coupled to the electronics subsystem, wherein the housing facilitates coupling of the system to a head region of the user.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: February 5, 2019
    Assignee: Emotiv, Inc.
    Inventors: Tan Le, Geoffrey Mackellar
  • Patent number: 10194824
    Abstract: A method for using electrical stimulation for cerebral network analysis. A first source localization procedure is performed, including a first source measurement procedure which produces first source measurement data, using the first source measurement data to find a solution to a first ill-posed problem which provides a first estimated location of the source. The body is electrically stimulated by targeting the first estimated location, and a second, fast source measurement procedure producing second source measurement data is performed thereafter while measurable effects of the step of stimulating, on the source, still remain. The second source measurement data are compared with the first source measurement data for assessing an extent to which the first estimated location is correct.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: February 5, 2019
    Assignee: PHILIPS NORTH AMERICA LLC
    Inventors: Don M. Tucker, Erik Anderson, Phan Luu
  • Patent number: 10198071
    Abstract: The application discloses various methods and apparatuses for determining control information. One of the methods for determining control information disclosed comprises: acquiring EEG detection information of a human body in response to a motion of a head of the human body; and determining control information corresponding to the EEG detection information. Embodiments of the application may facilitate achieving a more natural, flexible and convenient human-computer interaction by taking the motion of the head as a locus of control.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: February 5, 2019
    Assignee: Beijing Zhigu Rui Tuo Tech Co., Ltd.
    Inventor: Hao Liu
  • Patent number: 10180666
    Abstract: The present subject matter provides: a server and a method thereof; a communication device and a method thereof; and a controlled device and a method thereof. The present subject matter provides capturing of modification caused by the neural signals on a first signal. The present subject matter provides generation and broadcasting of the first signal which interacts with the neural signal. The neural signals correspond to instructions to operate a controlled device. The interaction between the first signal and neural signal causes modification of some characteristics of the first signal, resulting in a second signal. The second signal is than captured and analyzed for generating a command corresponding to the second signal. The command is reflective of the instructions to operate the controlled device and the subject matter provides causing the controlled device to operate according to the command.
    Type: Grant
    Filed: January 1, 2015
    Date of Patent: January 15, 2019
    Inventor: Abhijeet R. Satani
  • Patent number: 10172567
    Abstract: The present invention describes systems and methods for predicting and detecting a seizure in a subject. The methods of the invention comprise measuring interneuron synchrony in terms of the coherence between interneuron action potentials and local field potential oscillations. In one embodiment, the detection of specific patterns of coherence, correlation and firing rate of interneurons predicts an upcoming seizures.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: January 8, 2019
    Assignee: Drexel University
    Inventors: Karen A. Moxon, Dane Grasse
  • Patent number: 10159417
    Abstract: There are provided an apparatus and a method for measuring pulse waves. The pulse wave measuring apparatus includes a receiver configured to receive pulse wave signals sensed at at least two points of an object; an analog signal processor configured to amplify a voltage difference between two pulse wave signals from among the received pulse wave signals and integrate the amplified voltage difference; and a digital signal processor configured to analog to digital convert a value of the integrated amplified voltage difference and obtain, from the converted value, a pulse transit time between the two points corresponding to the two pulse wave signals.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: December 25, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Sangyun Park, Jaemin Kang, Younho Kim, Yongjoo Kwon, Sunkwon Kim
  • Patent number: 10143483
    Abstract: A device for treating the human or animal brain with shockwaves has a shockwave transducer coupled to a position sensor for detecting the position of the shockwave transducer. The device is adapted to evaluate the signals of the position sensor to calculate the position of the focus spot of the shockwave transducer. Furthermore, a mapping device is provided for mapping the movement of the focus spot over a plurality of positions together with the applied shockwave dose at each of the positions. The applied shockwave dose may be indicated on a color display.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: December 4, 2018
    Assignee: STORZ MEDICAL AG
    Inventors: Ernst Marlinghaus, Gerold Heine
  • Patent number: 10137276
    Abstract: The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slow wave activity is related to sleep pressure. Sleep pressure dissipates and/or decreases as the subject sleeps. The dissipation dynamics depend on a given subject. The manner in which dissipation occurs regulates the length of the given sleep session and is linked to the temporal dynamics of slow wave activity. The system is configured to determine a metric indicating sleep pressure dissipation and, responsive to the determined sleep pressure dissipation metric indicating that sleep pressure dissipation has reached a dissipation threshold level during the sleep session, wake the subject.
    Type: Grant
    Filed: April 20, 2014
    Date of Patent: November 27, 2018
    Assignee: Koninklijke Philips N.V.
    Inventors: Gary Nelson Garcia Molina, Giulio Tononi, Sander Theodoor Pastoor, Stefan Pfundtner, Brady Alexander Riedner, Michele Bellesi
  • Patent number: 10132891
    Abstract: A PET-MRI system for imaging an object is provided. The PET-MRI system includes a magnetic resonance imaging sub-system, a positron emission tomography sub-system, an optical sensor, and a data processing controller. The magnetic resonance imaging sub-system includes a surface coil that acquires magnetic resonance signals from the object. The positron emission tomography sub-system acquires PET emissions from the object. The optical sensor detects at least one of a spatial location and a shape of the surface coil. The data processing controller communicates with the magnetic resonance imaging sub-system, the positron emission tomography sub-system, and the optical sensor, and utilizes at least one of the detected spatial location and the detected shape of the surface coil to correct the acquired PET emissions for attenuation.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: November 20, 2018
    Assignee: General Electric Company
    Inventors: Jiaqi Li, Andrew Byshenk, Chinmoy Goswami, Tongzhou Wang
  • Patent number: 10123735
    Abstract: Disclosed is a method for an electronic device. The method may include: acquiring a galvanic skin response; generating a first parameter for a first interval and a second parameter for a second interval based on the galvanic skin response, the second interval being an interval before the first interval; determining a first threshold corresponding to the first interval based on the second parameter; and determining an activity state of the first interval based on the first threshold and the first parameter corresponding to the first interval.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: November 13, 2018
    Assignees: Samsung Electronics Co., Ltd., Seoul National University R&DB Foundation
    Inventors: Hyun-Jae Baek, Kwang-Suk Park, Sang-Bae Park, Do-Yoon Kim, Jung-Taek Oh, Jae-Geol Cho, Byung-Hun Choi, Sang-Won Seo, Hee-Nam Yoon, Da-Woon Jung, Sang-Ho Choi, Su-Hwan Hwang
  • Patent number: 10123750
    Abstract: The present invention provides methods and devices for predicting, preventing, detecting and/or treating seizures. In some embodiments, the present invention provides methods/devices for predicting a seizure prior to its inception, wherein the seizure is predicted based upon neuronal activity in the CA3 region of a patient's hippocampus.
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: November 13, 2018
    Assignee: Wake Forest University Health Sciences
    Inventors: Mark R. Witcher, Robert E. Hampson, Sam Deadwyler, Daniel E. Couture, Gautam Popli
  • Patent number: 10127929
    Abstract: In a system and method for assessing the condition of a subject, control parameters are derived from a neurophysiological computational model that operates on features extracted from a speech signal. The control parameters are used as biomarkers (indicators) of the subject's condition. Speech related features are compared with model predicted speech features, and the error signal is used to update control parameters within the neurophysiological computational model. The updated control parameters are processed in a comparison with parameters associated with the disorder in a library.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: November 13, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Thomas Francis Quatieri, Jr., Gregory Alan Ciccarelli, Satrajit S. Ghosh, Christopher J. Smalt, James R. Williamson, Jeffrey Shane Palmer
  • Patent number: 10121063
    Abstract: A wink gesture based control technique for selecting, controlling and manipulating virtual objects and smart applications on a display using facial gestures of the user, in particular winking, blinking and squinting movements of the eyes. The wink gesture based control technique utilizes wink gestures of a user to select, control, and manipulate virtual objects on a display. A head mounted device is adapted to allow detection and classification of specific wink gestures. The head mounted device in some embodiments may also be adapted to recognize certain characteristics of the wink gestures, such as duration or amplitude, to allow enhanced navigation of a computer interface.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: November 6, 2018
    Assignee: BMT BUSINESS MEETS TECHNOLOGY HOLDING AG
    Inventor: Maximilian Ralph Peter von und zu Liechtenstein
  • Patent number: 10111622
    Abstract: An instrument that utilizes body contact electrodes evaluates the quality of the connections made between the electrodes and the body. An electrode contact quality evaluation circuit performs the quality evaluation, such as by determining contact impedances for the electrodes. The corresponding contact quality of each electrode is conveyed to the user.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 30, 2018
    Assignee: WELCH ALLYN, INC.
    Inventor: Richard A. Sunderland
  • Patent number: 10111617
    Abstract: A patient monitoring system includes an electroencephalography (EEG) monitor and an EEG sensor array. The EEG sensor array includes a plurality of electrodes configured to acquire EEG signals from a patient. The EEG monitor may be configured to calculate one or more depth of anesthesia indices for the patient based on received EEG signals from the EEG sensor array. Additionally, the EEG monitor may be configured to generate and display a topographic color map of the calculated depth of anesthesia indices.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: October 30, 2018
    Assignee: Covidien LP
    Inventor: Darshan Ramesh Iyer
  • Patent number: 10112066
    Abstract: A device and method for alleviating extremity pain and improving range of motion using a mobile mirror with functional activity attachments. Secured symmetrical functional objects for manipulation are positioned either along side, in front, or on the mirror itself. The individual looks at the reflection of the non-affected extremity manipulating the functional attachment while both extremities perform the activity. The occupational therapy device is simple to use and can relocate to either tabletop or floor. The large mirror accommodates longer arms and legs for improved visual field and can be rotated for either vertical or horizontal orientation.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: October 30, 2018
    Assignee: AJL LLC
    Inventors: Amy De Maagd Heathfield, Julie M. DeBoer, Leo G. DelCarmen, II
  • Patent number: 10105538
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: October 23, 2018
    Assignee: Cyberonics, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson
  • Patent number: 10098582
    Abstract: Systems and methods are provided for quantitatively and objectively characterizing sleep architecture in normal individuals and persons with various health conditions. Embodiments of the invention facilitate characterizing temporal-pattern information of an individual's sleep, such as measured by electroencephalography (EEG), for identifying persons with abnormalities in the temporal-pattern information, sequences or durations of their stages of sleeping (“sleep architecture”), for facilitating selecting appropriate therapy or treatment, and for monitoring the effectiveness of such therapy or treatment. In one aspect, a set of time series are formed by electronically representing and storing information pertaining to brain activity, such as EEG hypnogram or sleep information, over a multi-night span.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: October 16, 2018
    Assignee: Cerner Innovations, Inc.
    Inventors: Douglas S. McNair, Kanakasabha Kailasam, William Stadler
  • Patent number: 10098562
    Abstract: A device and a method for detecting a brain response state of a subject id disclosed. The detection comprises repeatedly presenting the subject with a sound stimulus for evoking a brain response. Detecting the evoked brain response signal related to each of said sound stimulus. Determining a window having a time width covering at least partly an area of at least one neuron's evoked response in the brain response signal. Calculating an average response signal over the window and comparing the at least one neuron's evoked response with the average response signal for determining a cellular variance and/or volatility.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: October 16, 2018
    Assignee: SensoDetect AB
    Inventor: Johan Källstrand
  • Patent number: 10091554
    Abstract: Media content recommendation systems and methods are operable to recommend one or more media content events to a user based on identified changes in the user's emotional state during a life event that is experienced by the user.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: October 2, 2018
    Assignee: EchoStar Technologies L.L.C.
    Inventors: Nicholas Newell, Prakash Subramanian
  • Patent number: 10085684
    Abstract: States are identified in a time ordered sequence of data that have a temporal component. Data that includes a plurality of snapshots is received. Each snapshot of the plurality of snapshots includes a plurality of sensor measurements captured from distinct sensors at a common time point. The plurality of snapshots are time ordered. Root mean square error (RMSE) values are computed between successive pairs of the plurality of snapshots in time order. A peak is identified in the computed RMSE values. A valley is identified in the computed RMSE values. A stable state is determined as occurring from the identified peak to the identified valley. The determined stable state is output.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: October 2, 2018
    Assignee: The University of Chicago
    Inventors: Stephanie Cacioppo, John T. Cacioppo, Robin M. Weiss
  • Patent number: 10064578
    Abstract: Systems and methods to detect sleep stages of a subject analyze physiological parameters of the subject in combination with a subject's reactions to stimuli of increasing intensity and/or stimuli having different modalities. Stimuli are provided until a predetermined level of probability is reached for the accuracy of an estimation of the sleep stage of the subject.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: September 4, 2018
    Assignees: Koninklijke Philips N.V., Wisconsin Alumni Research Foundation
    Inventors: Gary Nelson Garcia Molina, Sander Theodoor Pastoor, Stefan Pfundtner, Brady Alexander Riedner, Michele Bellesi, Giulio Tononi
  • Patent number: 10068490
    Abstract: A system and method for improving student learning includes learning material that is presented to a student and a device that is used to acquire physiological data from the student in real time during a learning session. A cognitive assessment algorithm determines a cognitive state of the student using the physiological data, and a learning action algorithm modifies the presentation of the learning material in response to the student's cognitive state. The learning material can include lectures, questions asked of the student or problems or activities being completed by the student. In one embodiment, the device directly measures the brain activity of the student to determine the student's cognitive state. The cognitive state of the student can include the student's cognitive load, engagement or fatigue.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: September 4, 2018
    Assignee: Quantum Applied Science and Research, Inc.
    Inventors: Andrew D. Hibbs, Walid V. Soussou, Jason D. Jolly, Igor V. Fridman
  • Patent number: 10061891
    Abstract: A system and method for the analysis of biopotential signals using motion artifact removal techniques is disclosed. The system includes a motion classification module configured to receive at least one biopotential signal and at least one reference secondary input signal. The motion classification module performs motion artifact classification for determining motion meta-information, comprising a type and/or severity indication about motion phenomena causing artifacts in the biopotential signal. The motion classification module communicates motion meta-information to a motion artifact reduction module configured to remove motion artifacts from the biopotential signal based on the information received from the motion classification module.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: August 28, 2018
    Assignee: Stitching IMEC Nederland
    Inventors: Bernard Grundlehner, Vojkan Mihajlovic
  • Patent number: 10058279
    Abstract: Provided is a sleep and activity amount display program that allows easy checking of sleep data along with activity amount data for each time period of a certain day. The sleep and activity amount display program includes a step of obtaining sleep data of a user from a sleep measurement device; a step of obtaining activity amount data of a user from an activity measurement device; a step of creating a time display image divided into time slots that each indicate a predetermined range of time; and a step of plotting a getting-up time and a bedtime included in the sleep data as well as the activity amount data on the time slots of the time display image.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: August 28, 2018
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Yasuko Emori, Yoko Kanemitsu, Feilang Tseng
  • Patent number: 10046171
    Abstract: A transcranial magnetic stimulation device in accordance with embodiments of the present invention comprises a head mount for disposition on a head of a patient and configured with a plurality of attachment points, a plurality of magnetic assembly devices connected to the plurality of attachment points, a given magnetic assembly device equipped with an actuator device to actuate a magnet, is addressable, and configured to receive a control signal addressed to the given magnetic assembly device, and a processor having a memory and configured by program code. The processor is configured to: select one or more treatment protocol units, generate a control signal using at least information contained in the selected treatment protocol units, energize at least one magnetic assembly device over a period of time to cause the magnet to actuate according to the control signal, and monitor the patient response to energizing to addressable actuator.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: August 14, 2018
    Assignee: SERAYA MEDICAL SYSTEMS LLC
    Inventor: Leeam Lowin
  • Patent number: 10045718
    Abstract: A wearable sensor vehicle with a bio-input sensor and a processor. When the vehicle is worn, the sensor is arranged so as to sense bio-input from the user. The sensor senses bio-input, the processor compares the bio-input to a standard, and if the standard is met the processor indicates a response. The user may be uniquely identified from the bio-input. One or more systems on or communicating with the vehicle may be controlled transparently, without requiring direct action by the user. Control actions may include security identification of the user, logging in to accounts or programs, setting preferences, etc. The sensor collects bio-input substantially without instruction or dedicated action from the user; the processor compares bio-input against the standard substantially without instruction or dedicated action from the user; and the processor generates and/or implements a response based on the bio-input substantially without instruction or dedicated action from the user.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: August 14, 2018
    Assignee: Atheer, Inc.
    Inventors: Allen Yang Yang, Mohamed Nabil Hajj Chehade, Sina Fateh, Sleiman Itani
  • Patent number: 10039471
    Abstract: A biofeedback system that utilizes isochronic tone technology to augment EEG feedback by providing to a subject isochronic tones at the frequency of a targeted aspect of a subject's brain waves, such as the brain's naturally occurring peak energy in the particular EEG band or bands subject to the biofeedback. Isochronic tones are regular beats of a single tone that are formed by separate pulses of sound and silence. In addition, feedback can be provided to the subject in the form of pulsed light and pulsed tactile impulses that are delivered in the form of alternating presence and absence of light or tactile pressure.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: August 7, 2018
    Inventor: James V. Hardt
  • Patent number: 10039465
    Abstract: The invention relates to a method for automatically evaluating an absence EEG, wherein EEG curves are recorded by an evaluating device and are evaluated by means of a computer of the evaluating device, wherein in the evaluation at least the current stage of the absent state is determined from the EEG curves by means of the computer on the basis of a stage division of the absence EEG, wherein stages of the depth of the absent state are distinguished in the stage division, and wherein the current stage is output, wherein a certain scheme of the stage division is selected by the computer from a plurality of selectable schemes of stage divisions, which differ in the number of distinguishable stages of the absent state, and is used for the automatic performance of the stage division in order to determine the current stage. The invention further relates to a computer program for performing such a method and to an evaluating device for evaluating an absence EEG.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: August 7, 2018
    Inventor: Arthur Schultz
  • Patent number: 10043129
    Abstract: A computer-implemented method for performing a functional assessment of a network is disclosed. The network includes a plurality of interacting network elements. The method includes measuring a state of each of the elements at a plurality of time instances, thereby determining a plurality of state values associated with each of the elements, and calculating for each element an associated median value representing a median of the state values associated with that element. The method further includes identifying for each time instance a first total number of elements with an associated state value at that time instance that is above its median value, and a second total number of elements with an associated state value at that time instance that is below its median value, and determining whether the network has departed from an equilibrium state based on the first total number and the second total number for each time instance.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: August 7, 2018
    Assignees: Regents of the University of Minnesota, Department of Veterans Affairs
    Inventor: Apostolos Georgopoulos
  • Patent number: 10019642
    Abstract: An image upsampling system, a training method thereof and an image upsampling method are provided, the feature images of an image are obtained by using the convolutional network, upsampling processing is performed on the images with the muxer layer to synthesize every n×n feature images in the input signal into a feature image with the resolution amplified by n×n times, in the upsampling procedure with the muxer layer, information of respective feature images in the input signal is recorded in the generated feature image(s) without loss; and thus, every time when the image passes through a muxer layer with an upsampling multiple of n, the image resolution can be increased by n×n times.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: July 10, 2018
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Pablo Navarrete Michelini, Lijie Zhang, Jianmin He
  • Patent number: 10004446
    Abstract: We report a method for detecting epileptic or non-epileptic seizures, comprising: receiving a heart rate of a patient; calculating a percentage change of the heart rate in reference to at least one of the patient's maximal heart rate, reserve heart rate, or a resting heart rate; detecting an epileptic seizure if the percentage increase in the heart rate reaches a threshold value; and taking at least one responsive action selected from issuing a warning, delivering a therapy, determining a seizure severity, or logging at least one of a date and time of occurrence of the seizure, its severity, the type of therapy, or its effect, in response to the detection. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: June 26, 2018
    Inventor: Ivan Osorio
  • Patent number: RE47266
    Abstract: An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: March 5, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Thomas DiMauro, Mohamed Attawia, Sean Lilienfeld, Chantal Holy, Jeffrey K. Sutton, Michael Ward