Abstract: An electrode cap for obtaining EPM signals from a head of a subject, the cap comprising: (i) an insulating layer (33) for positioning adjacent to the head of the subject; (ii) an electrically conductive layer (29) comprising ionic conduction means, situated above the insulating layer so that in use, it is separated from the head of the subject by the insulating layer; (iii) a plurality of measurement signal electrodes (13) extending through the electrically conductive layer and the insulating layer for contacting the head of the subject, the measurement signal electrodes being electrically insulated from the electrically conductive layer; and (iv) at least one reference node (53, 55) electrically connected to the electrically conductive layer.

Abstract: There is provided a technique which, in the case where the operation has not occurred in a manner as expected by the user, determines from which standpoint the operation was not as expected, and makes a response that is closer to the expectation. An information processing system according to the present invention includes: a reaction section for executing a first process based on a request from a user; an output section for outputting a result of a process; a signal detection section for measuring a signal concerning an event-related potential of electroencephalograms of the user; an analysis section for identifying a positive peak in the event-related potential and determining whether an elapsed time since the result is output and until the peak appears is closer to a first reference time or a second reference time; and a reaction modifying section for determining a second process in accordance with the determination result.

Abstract: A method of training a subject to improve anticipatory timing includes presenting the subject with multiple sequences of stimuli, receiving sensor signals associated with responses by the subject to the stimuli, and recording response times in accordance with the sensor signals, wherein the recorded response times are associated with the responses by the subject to the multiple sequences of stimuli, and wherein the response times have an associated distribution. The method further includes analyzing the distribution of response times for the subject to determine variability in anticipatory timing of the subject with respect to the stimuli, and generating a subject feedback signal corresponding to a result of the analyzing so as to train the subject to improve anticipatory timing of the subject. Also disclosed is a system for performing the aforementioned training method.

Abstract: Described is a system and method which includes the following steps. A plurality of interventional agents are administered to a patient until the patient attains a predetermined plane of anesthesia. Brain waves of the patient are amplified and digitized before and after the administering step to generate a first set of digital data. The brain waves of the patient are amplified and digitized during a medical procedure to generate a second set of digital data. Separate trajectories for at least two different indices of an anesthetic state of the patient are computed during the medical procedure as a function of a comparison of the first and second sets of digital data. The indices include a Depth Index (DI), a Memory Index (MI) and a Pain Index (PI). The DI corresponds to a depth of anesthesia of the patient, the PI corresponds to a sensitivity of the patient to pain and the MI corresponds to an ability of the patient to form and store memories.

Abstract: A biofeedback system for administration of electroencephalographic (EEG) neurofeedback training includes a plurality of electrodes sensors for placement on the head of a trainee and a switching head box comprising a plurality of contacts each of which connects to one electrode sensor and for specific biofeedback and neural connectivity training. The system also includes an interface device which includes at least two EEG signal amplifiers and connects to the switching head box, and a computer comprising software for generating user-control functions which corresponds in real-time to EEG signals received by the interface device and processed by the computer. The switching head box includes a switch with at least two conductors and connects the electrode sensors to the interface device for transmitting EEG signals from the trainee to the computer. Specific combinations of electrode sensors are used for specific types of biofeedback training.

Abstract: Treatment apparatus and method for the enhancement of neurophysiological processes of a patient's visual system utilizes a computer generated display that provides a patient simultaneously with passive visual stimulation images and visual cognitive exercises. The stimulation images include moving elements having edges or points of contrast. The exercises include visual and phonological elements. The invention is used to treat reading, writing and speech disorders, and attention deficit hyperactivity disorder, as well as having broader applications for example in sports sciences.

Abstract: A system includes a port to receive brain activity data of a user, a processor to detect a beginning time of a user nap based upon the brain activity data, and a user interface to notify the user when a predetermined nap time has elapsed. A method of monitoring a user somnolence level receives brain activity data from a user, and determines a somnolence level from the brain activity data. If the somnolence level is sleep, the system determines if a nap has progressed to a waking point, and if the nap has progressed to a waking point, alerts the user.

Abstract: The invention relates to a method and apparatus for detecting artifacts in a bioelectric signal, especially in a frontal EEG signal. In order to accomplish an uncomplicated mechanism for detecting artifacts in clinical applications, an impedance signal is measured through a first electrode set attached to the skin surface in a measurement area of a patient's body, the impedance signal being indicative of the impedance of the signal path formed between individual electrodes of the set. Simultaneously with the impedance measurement, a bioelectric signal is acquired through a second electrode set also attached to the skin surface of the measurement area, and the time periods are determined during which the impedance signal fulfills at least one predetermined criterion indicative of the presence of artifact in the bioelectric signal. In one embodiment, the first and second electrode sets are formed by a common set of two electrodes.

Abstract: A system and method for a neural interface system with integral calibration elements may include a sensor including a plurality of electrodes to detect multicellular signals, an interface to process the signals from the sensor into a suitable control signal for a controllable device, such as a computer or prosthetic limb, and an integrated calibration routine to efficiently create calibration output parameters used to generate the control signal. A graphical user interface may be used to make various portions of the calibration and signal processing configuration more efficient and effective.

Abstract: A method for incorporating brain wave entrainment into an audio composition by selectively modulating musical elements within the composition. The invention provides a way to specify and modulate individual frequency components in an audio composition, according to the desired brain wave state, allowing brain wave entrainment to be easily and subtly incorporated into an audio composition by disguising the modulations as natural instrumental qualities such as vibrato or reverberation.

Abstract: Methods, systems and computer program products for retrieving mental images of faces from the human brain. An exemplary embodiment includes a method for retrieving mental images of faces from a human brain, the method including generating an image on a screen, measuring brain activity data from a brain scanner, varying characteristics of the image on the screen, detecting changes in the brain activity data measured from the brain scanner, and generating a final image on the screen, the final image being related to a subjectively described mental image.

Abstract: An apparatus and process for low energy neurofeedback includes computer and display means on a general purpose computer to calculate and display dominant brain wave frequencies as measured by an electroencephalogram. The general purpose computer is also operative to compute and display a new frequency that is offset from the dominant frequency by 5 to 20 Hz. A therapeutically beneficial low power RF field is generated in the EEG leads merely by the computation and display of the new frequency without the need to deliberately power the EEG leads.

Abstract: Systems and methods for portable neurofeedback are disclosed herein. In an embodiment, a neurofeedback system includes sensors for capturing, recording and transmitting brain electrical activity; and a portable device for receiving, processing and displaying in real-time the brain electrical activity, wherein the brain electrical activity is provided visually on the portable device as visual feedback. In an embodiment, the portable device further includes speakers for implementing auditory feeedback based on the recorded brain electrical activity. In an embodiment, the portable device further includes at least one vibration feedback motor for implementing vibratory feedback based on the recorded brain electrical activity.

Abstract: Devices, systems and methods are disclosed for a neural access device that includes an implant which transcutaneously exits the skin of a patient and provides transport of signals between a sensor implanted in a patient and an external device. The transcutaneous implant has integrated features to provide reduced risk of injury due to mechanical forces as well as electrostatic discharge energy applied to the external portion of the device. Transcutaneous devices which provide wireless communication between a sensor and an external device are also disclosed.

Abstract: A method and apparatus using brainwaves to control real objects is provided. The method and apparatus comprise using sensors to detect the brain's electrical signals and transmit at least two brainwaves to an apparatus that converts the brainwaves into a format usable by a signal processor. The signal processor determines a coherence between portions of the brainwaves, typically in the frequency domain, and compares the coherence values, which change rapidly from moment to moment, to thresholds. Based on the comparison of the coherence value to the thresholds, which are adjusted over time based on feedback relating to success, a control signal is developed that can be sent to a real object to control 3 dimensional motion of the control object.

Abstract: Apparatus and methods for monitoring electrical activity within the brain of a person (“brainwaves”) employing electrodes or other sensors connected or placed proximate to portions of the body below the head to develop raw signals. The raw signals are filtered to produce analysis signals including frequency components relevant to brain electrical activity while attenuating unrelated frequency components. Purposes include but are not limited to, biofeedback-based attention training, human performance training, gaming, and relaxation training. Either wired or wireless signal connections are made to electronic circuitry, typically including a digital computer, for performing signal processing and analysis functions.

Abstract: A system (10) analyzes signals representative of a subject's brain activity in a signal processor (12) for information indicating the subject's current activity state and for predicting a change in the activity state. One preferred embodiment uses a combination of nonlinear filtering methods to perform real-time analysis of the electro-encephalogram (EEG) or electro-corticogram (ECoG) signals from a subject patient for information indicative of or predictive of a seizure, and to complete the needed analysis at least before clinical seizure onset. The preferred system then performs an output task for prevention or abatement of the seizure, or for recording pertinent data.

Abstract: An intelligent control system based on an explicit model of cognitive development (Table 1) performs high-level functions. It comprises up to O hierarchically stacked neural networks, Nm, . . . , Nm+(O?1), where m denotes the stage/order tasks performed in the first neural network, Nm, and O denotes the highest stage/order tasks performed in the highest-level neural network. The type of processing actions performed in a network, Nm, corresponds to the complexity for stage/order m. Thus N1 performs tasks at the level corresponding to stage/order 1. N5 processes information at the level corresponding to stage/order 5. Stacked neural networks begin and end at any stage/order, but information must be processed by each stage in ascending order sequence. Stages/orders cannot be skipped. Each neural network in a stack may use different architectures, interconnections, algorithms, and training methods, depending on the stage/order of the neural network and the type of intelligent control system implemented.

Abstract: Systems, Methods, and Computer Program Products for Transmitting Neural Signal Information. Systems, method, and computer program products are provided for neural signal transmission. A system according to one embodiment can include a signal receiver operable to receive a neural signal comprising an action potential. The system can also include an action potential detector operable to communicate with the signal receiver and detect when the action potential occurs. In addition, the system can include a transmitter in communication with the action potential detector and operable to transmit an information signal indicating the time when the action potential occurs and, in addition, can transmit samples associated with a detected action potential.

Abstract: The claimed subject mater provides systems and/or techniques that provide biometric feedback monitoring of brain activity. The system includes mechanisms that obtain indication of brain activity associated with an individual which can be utilized to ensure that the individual is maximizing his or her brain activity. Where it is determined that the individual is not optimally utilizing his or her brain, feedback can be directed to the individual in order to stimulate brain activity in a specified response center of the brain.

Abstract: A method and a Cranial Electrical Stimulator CES for operation in a diagnosis, treatment, research, and test mode related to brain disorders, namely to mental disorders, and to neurological disorders, such as migraine and epilepsy, are disclosed. Diagnosis is based on a detected condition of passage of an electric signal via a pathway in the brain defined as passing from a first to a second electrode of a pair of electrodes from an array attached to the skull of a patient. Treatment is achieved by injecting a treatment signal in the pathway detected as having a condition. A practitioner operates a workstation of the CES that controls a signal and routing box SRB generating input signals and receiving output signal from the brain, via the skull and electrodes. The PC of the workstation controls signal input, output reception, measurement, display and storage in memory.

Abstract: A method of assisting a user in bringing a plurality of EEG electrodes into proper contact with the user's scalp includes receiving a signals from EEG electrodes, determining a state of contact with the user's scalp, and displaying a representation of the user's scalp and an indicator of the state of contact, the indicator positioned on the representation in a position representative of a position of an associated electrode on the user's scalp. Determining quality of contact of an electrode on a user can includes applying a reference signal to a user, receiving a measured signal from an electrode for monitoring bioelectric signals of the user, and determining a state of contact of the electrode with the user based on the measured signal and the reference signal.

Abstract: The present invention discloses an automatic bio-signal supervising system for medical care. The automatic bio-signal supervising system utilizes a head-mounted bio-signal acquisition device, wore upon the user's head, to acquire the bio-signals, convert them into the digital bio-signals, and transmit the digital bio-signals to a signal analysis processor to perform analysis process. And the automatic bio-signal supervising system delivers a corresponding control signal to the environment control equipment based on the result of analysis, and control the environment condition to achieve the remote supervising and medical care purpose. Furthermore, the signal analysis processor in the present invention further provides a real-time warning signal or a health index, which supervise the personal biological information to avoid the unpredictable situation.

Abstract: A method and apparatus to monitor and control the anesthesia state of a patient undergoing general anesthesia is provided. Previous automated systems to monitor the anesthesia state of a patient undergoing general anesthesia involve a significant time delay between the patient's true anesthesia state and the computed indices. The present invention reduces this time delay by using a novel analysis technique applied to spontaneous electrophysiological activity. A transformation and statistical analysis of the observed electrophysiological activity is conducted and compared to reference data to provide numerical indicators. In addition, these indicators are consistent with the levels of depression of patients CNS and ANS states. This method is illustrated in detail by CNS monitoring of electroencephalogram signals.

Abstract: The invention relates to a method for positioning electrodes in an electrode array comprising a plurality of electrodes for central nervous system (CNS) monitoring from the forehead of a subject. In order to enable efficient detection of eye movement artifacts with a minimum number of electrodes, first and second electrodes are positioned so that eye movement in one of the horizontal or vertical directions causes a negligible overall voltage change between the first and second electrodes and at least a third electrode is positioned so that eye movement in the other of said horizontal and vertical directions causes a high potential difference between the third electrode and an auxiliary electrode, wherein the auxiliary electrode is one of the electrodes in a set comprising one of the first and second electrodes and a fourth electrode.

Abstract: A system and method for performing a vision examination includes displaying a series of visual stimuli for observation by a patient and detecting the patient's visual evoked potentials in response to the visual stimuli. Electrical signals representative of the visual evoked potentials for each stimulus of each series of visual stimuli displayed is amplified, converted to digitized data, recorded and measured. The measured visual evoked potential data is then evaluated and compared to certain predetermined values in order to detect whether or not the measured data is reliable. Data outside of predetermined ranges of values is considered faulty data. For example, the measured data is compared to a maximum value of the output of an amplifier used to enhance the electrical signals, to a predetermined value of the Fourier component at 60 Hz; and to certain ranges to determine if the measured data are outside of expected limits. The occurrence of such data outside these ranges is faulty data.

Abstract: Described herein are methods of optimizing an interactive media (e.g., a videogame) based on a brain activity criterion, as well as interactive media optimized or incorporating these methods. Brain activity may be measured using imaging techniques, such as an fMRI image of neural activity taken while a subject is using the technology. The optimization may be used to help the interactive media evoke desired behaviors or attitudes in subjects who have used the interactive media. For example, the interactive media described herein may be optimized to help facilitate behaviors or attitudes that are conducive to medical therapies, including compliance with medical treatments.

Abstract: An electroencephalogram interface is activated by utilizing a biological signal, in particular a steady-state visual evoked potential, from a user. An electroencephalogram interface system (1) includes a biological signal detection section (4) for detecting an electroencephalogram signal from a user (3) and a control section (5) for distinguishing a component of an event-related potential which is contained in the electroencephalogram signal and causing a device to operate based on the distinguished event-related potential. The electroencephalogram interface system (1) further includes an activation apparatus (2) for activating the control section (5) and an output section (6) for presenting a visual stimulation which flickers with a predetermined frequency based on a signal from the activation apparatus (2).

Abstract: The present invention is aimed at improving efficiency of therapeutic action. The above technical effect is achieved in a device for physiotherapeutic treatment of diseases of various etiology comprising a control unit 1 connected to a color action unit 30, an intracavitary action unit 28 embodied in the form of a rectal and/or vaginal probe within which a laser and a source of magnetic field and/or a catheter are located, an epicutaneous action unit 29 embodied in the form of an epicutaneous electrode, and/or an epicutaneous radiator embodied in the form of a case containing sources of magnetic field and color action; said the device being provided with a means 31 for recording electroencephalogram with a unit 32 for dividing thereof into three frequency ranges with a separate output for each range, each output being connected through the control unit 1 to a separate monochromatic radiation former of the color action unit 30.

Abstract: Methods and apparatus are provided for evoking perceptions of affordances in a user/virtual environment interface. The method involves recognizing the absence or inadequacy of certain sensory stimuli in the user/virtual environment interface, and then creating sensory stimuli in the virtual environment to substitute for the recognized absent or inadequate sensory stimuli. The substitute sensory stimuli are typically communicated to the user (e.g., visually and/or audibly) as properties and behavior of objects in the virtual environment. Appropriately designed substitute sensory stimuli can evoke perceptions of affordances for the recognized absent or inadequate sensory stimuli in the user/virtual environment interface.

Abstract: A drowsiness detection system is disclosed. The way of detection is by an EEG detection circuit to detect brain waves of a human brain for getting an EEG signal. The EEG signal is sent to a micro-controller circuit to generate a control signal. In accordance with the control signal, a processing circuit processes the EEG signal so as to learn the drowsiness state of the user in time.

Abstract: A system for accessing the brain of a subject to record and/or stimulate brain stares thereof. The system includes control means, first accessing means having a plurality of contact surfaces configured to operatively connect the control means to the brain of the subject to provide three-dimensional stimulation thereof; second accessing means having a plurality of contact surfaces to operatively connect the control means to the brain of the subject to provide access thereto for the purposes of obtaining three-dimensional recordings of the brain electrical activity of the subject; and a waveform bank containing a plurality of stimulating waveforms.

Abstract: The invention relates to a method and apparatus for assessing the reactivity observable in a certain physiological signal, especially the EEG signal, of a subject. In order to obtain a compact measurement arrangement that enables reliable assessment of changes in the reactivity of the subject even during a long time period, a conventional monitoring device is provided with a stimulation module configured to supply stimuli to the subject through a measurement probe that the device uses to receive physiological signal data from the subject. The measurement probe may comprise, for example, an arm cuff through which the device monitors the blood pressure of the subject.

Abstract: The subject disclosure relates to a method and system for visual object categorization. The method and system include receiving human inputs including data corresponding to passive human-brain responses to visualization of images. Computer inputs are also received which include data corresponding to outputs from a computerized vision-based processing of the images. The human and computer inputs are processing so as to yield a categorization for the images as a function of the human and computer inputs.

Abstract: A method of whole-brain EEG neurofeedback training of a trainee using live Z-scores from 4 channels of EEG signals to acquire 248 Z-scores from 6 simultaneous interconnectivity paths. The feedback system is endowed with the ability to establish training targets and to use derived metrics to produce feedback of an auditory, visual, vibrotactile, or other sensory or direct nature. The feedback signals are determined by a multivariate analysis that takes into consideration how measured variables compare with predefined criteria, thus producing a statistical correlation in real-time, in conjunction with a reference or normative database, rule-set, algorithm, discriminate function, or classification system.

Abstract: The present invention provides a device for inhibiting melatonin suppressing light from reaching the retina. The device having means for selectively blocking light having a wavelength capable of suppressing melatonin production in a human.

Abstract: A system and method for adaptive therapeutic intervention to effect real-time changes in the behavioral profile of an individual to facilitate the effectiveness of combined bioelectric sensing and biosensory based therapy for specific disorders. The system and method induces a temporary physiological state-of-mind (e.g., increased relaxation) to effect persistent changes to the cognitive-emotive profile of the individual (e.g., reduce internal tinnitus). The sense- and mental state-awareness responses, integrated into a two-way (i.e., bi-directional) feedback system using a dynamic interface with intelligently controlled thresholds. The invention takes into account details of multi-variate and nonlinear dynamics and database templates to more accurately compute the user's “state-of-mind.” It then utilizes this “state-of-mind” to drive therapeutic and non-therapeutic stimulus intervention.

Abstract: Systems and methods as described the present disclosure are capable of generating haptic feedback in response to sensing a biological signal from a vertebrate. A method according to one embodiment, among others, includes detecting a neural signal from a vertebrate. The method also includes generating a haptic effect on the vertebrate corresponding to the neural signal.

Abstract: An input section (101) receives a manipulation input of a user (50). A biological signal detection section (102) measures an event-related potential of electroencephalogram of the user (50). An operation error judgment section (103) judges using the event-related potential of the electroencephalogram of the user (50) at around 300 ms from a timing when the input section (101) receives the manipulation input as a starting point whether or not the manipulation input is due to an operation error of the user. An equipment operation control section (104) determines an operation of an equipment (1) based on a result of judgment by the operation error judgment section (103).

Abstract: This invention consists of a neurofeedback training system that utilizes EEG activity based goals to help motivate trainees to learn to produce and sustain desirable EEG activity by enabling them to earn “game play” time. The method provides positive behavioral reinforcement to trainees by rewarding them with the opportunity to begin or continue to participate in computer game-like or entertainment-based training activities (e.g., video games, educational games, movies, music or computerized cognitive training exercises) whenever the specified EEG activity goals are achieved and maintained for a set time period. The method also provides, in one embodiment, negative reinforcement in the form of the loss of game play or entertainment opportunities whenever the specified EEG activity goals are not achieved or maintained for a specified time interval.

Abstract: A patient advisory device (“PAD”) and its methods of use. The PAD may be configured to alert the patient about an estimated brain state of the patient. In preferred embodiments, the PAD is adapted to alert the patient of the patient's brain state, which corresponds to the patient's propensity of transitioning into an ictal brain state, e.g., having a seizure. Based on the specific type of alert, the patient will be made aware whether they are highly unlikely to have a seizure for a given period of time, an elevated propensity of having a seizure, a seizure is occurring or imminent, or the patient's brain state is unknown.

Abstract: The present invention relates to a sunglasses type device for detecting and preventing sleep and a method for detecting and preventing sleep.

Abstract: A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

Abstract: Methods and systems for modifying or enhancing vision are described. In exemplary embodiments, neural or neuromuscular activity is analyzed to determine a focus or other quality of a visual input, and the focus or quality information used as a basis for controlling an adjustable lens system or optical system.

Abstract: A method for controlling motion module via brainwaves uses brainwaves to control and drive a motion module. The motion module can perform motions in a plurality of motion modes. The method for controlling motion module via brainwaves includes: firstly, obtaining a plurality of brainwave signals. Then, the characteristic value of each of the brainwave signals is analyzed. Next, the characteristic values of the brainwave signals are compared to determine which specified motion mode of the plurality of motion modes the motion module should move in. Finally, the motion module is driven to move in the specified motion mode.

Abstract: A neural event electrode interface is configured to communicate with electrodes that capture electrical signals that are associated with at least one neuron. A neural event waveform processor is configured to extract neural events from the electrical signals. A wireless transmitter is configured to wirelessly transmit the neural events that are extracted from the electrical signals.

Abstract: A means and method for inducing a temporary physiological state-of-mind to effect persistent changes to the cognitive-emotive profile of an individual, which is adaptable for neurofeedback and “mental-state” therapeutic and non-therapeutic interventions. The system comprises an EEG Recording Module (ERM), a Neurodynamics Assessment Module (“NAM”), and a Transcranial Magnetic Stimulation module (“TMS”) for acquiring and manipulating bioelectrical and/or EEG data, defining a cognitive-emotive profile, and mapping the cognitive-emotive profile to selectively control transcranial magnetic stimulation to drive therapeutic and non-therapeutic stimulus interventions. A bi-directional feedback feature is provided to further enhance the performance of the system to effect prolonged changes.

Abstract: An apparatus and method for rehabilitating patients and assessing tactile skills in response to visual stimuli generated from a portable neural training device. The device generates a visual output to elicit tactile response (hand movement) from the patient. The device preferably automatically adjusts the difficulty of a session in response to demonstrated patient skill level (i.e. combination of correct responses, speed, and accuracy of responses). The invention evaluates and challenges the patient to control tactile response, overcome visual perception difficulties, or practice simple multi-tasking or reasoning skills. The invention also provides information which is valuable to those administering the rehabilitation program or assessing patient skill and/or progress. By way of example the neural training device is described with an embodiment having discrete fixed keys and an embodiment utilizing a touch sensitive display screen.

Abstract: The present invention concerns a method and system for encouraging physiologic change through physiological display control of video devices. The system includes interfacing an output from a physiologic acquisition device with a junction box that is capable of controlling the output of the physiologic acquisition device which can be an EEG, and whose output can be analog or digital, visually modulated output of the EEG signal or can be an audio feedback output of the EEG training signal. In one embodiment of the present invention, the PC is no longer required to process the audio/visual changes affected on the video device. The junction box can include means for changing the video feed characteristics such as brightness or darkness of the video image and also volume control of the video feed in response to changes in the signals of brain activity.

Abstract: Systems and methods of monitoring a subject's neurological condition are provided. In some embodiments, the method includes the steps of analyzing a physiological signal (such as an EEG) from a subject to determine if the subject is in a contra-ictal condition; and if the subject is in a contra-ictal condition, providing an indication (e.g., to the subject and/or to a caregiver) that the subject is in the contra-ictal condition. The systems and methods may utilize a minimally invasive, leadless device to monitor the subject's condition. In some embodiments, if the subject is in a pro-ictal condition, the method includes the step of providing an indication (such as a red light) that the subject is in the pro-ictal condition.