Liquid Collection Patents (Class 600/573)
  • Patent number: 11484433
    Abstract: A menstrual cup is provided whose body can expand to reveal an interior cavity in an open position configured to receive menstrual fluids and that can retract to a closed position such that the interior cavity of the menstrual cup is contained by the sides and body of the menstrual cup and any contained fluids are prevented from leaking out. A hook is coupled to a bottom surface of the body of the menstrual cup and can be pulled upon to close the menstrual cup and pushed upwards to open the menstrual cup. The retractability of the menstrual cup facilitates insertion into the vaginal cavity and removal without spillage of menstrual fluids. The menstrual cup includes a body with retractable sides that can close inwardly. A user can grasp the hook to manipulate the body of the menstrual cup from either a closed position or an open position.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: November 1, 2022
    Assignee: Tulia Feminine Care Co.
    Inventor: Ariana D. Miller
  • Patent number: 11484296
    Abstract: An endoscope (1) having a suction channel and a suction connector in communication with said suction channel, and a working channel through which a liquid may pass. A valve for diverting the suction through the sampling device through a sample container is provided. The endoscope (1) further includes an actuator (7) for propelling the liquid through said working channel.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 1, 2022
    Assignee: AMBU A/S
    Inventors: Lasse Markworth Johnsen, Jesper Mads Bartroff Frederiksen, Morten Sørensen
  • Patent number: 11473958
    Abstract: A printed circuit board device includes: a first capacitive sensor configured to measure a first capacitance within a contained volume having known dimensions, wherein the first capacitance changes as a substance is received into the contained volume; a second capacitive sensor having a plurality of trigger points at a plurality of corresponding known heights within the contained volume, the second capacitive sensor configured to detect when the substance received into the contained volume has reached each of the corresponding known heights within the contained volume; and wherein at least one of a level of the substance within the contained volume, a volume of the substance within the contained volume, or a flow rate of the substance into the contained volume is determined based on data from the first capacitive sensor and the second capacitive sensor.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: October 18, 2022
    Assignee: Stream Dx, Inc
    Inventors: Brian Holt, Scott McClellan, Alvin Y. Le, Kent Ogden
  • Patent number: 11464560
    Abstract: A self-limiting electrosurgical return electrode for use with electrosurgical procedures is disclosed. The return electrode includes a conductive element and pads disposed on opposing sides of the conductive element. The conductive element, optionally in combination with the pads, is configured to limit the density of electrical current that passes from a patient to the return electrode. The conductive element and the pads can cooperate to define two separate working surfaces on opposing sides of the return electrode. The return electrode can also be safely used with patients of substantially any size and without requiring adjustments to the power settings of an electrosurgical generator.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: October 11, 2022
    Assignee: Megadyne Medical Products, Inc.
    Inventors: Michael D. Ehninger, Paul R. Borgmeier, Darcy W. Greep, Roger Millis, Melissa K. Fischer
  • Patent number: 11445714
    Abstract: The present device is a specimen containment unit comprising; a container, wherein the container has a first portion of a locking mechanism positioned distal to an opening, and a funnel having a base and a plurality of segments attached to the base and a second portion of a locking mechanism integrated into the base, wherein the segments protrude a predetermined distance and angle from the base, wherein the first portion of the locking mechanism is designed to mate with the second portion of the locking mechanism to secure the funnel to the container.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: September 20, 2022
    Inventor: Thomas Fountain
  • Patent number: 11419533
    Abstract: The present disclosure relates generally to using detected bladder events for the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction. A system includes a sensing device comprising a pressure sensor to directly detect a pressure within a bladder. The sensing device is adapted to be located within the bladder. The system also includes a signal processing device to: receive a signal indicating the detected pressure within the bladder; detect a bladder event based the detected pressure within the signal; and characterize the bladder event as a bladder contraction event or a non-contraction event. The characterization of the bladder event can be used in the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: August 23, 2022
    Assignees: THE CLEVELAND CLINIC FOUNDATION, The United States Government as represented by the Department of Veterans Affairs, Case Western Reserve University
    Inventors: Margot S. Damaser, Swarup Bhunia, Robert Karam, Steve Majerus, Dennis Bourbeau, Hui Zhu
  • Patent number: 11415550
    Abstract: The invention relates to a sensor for measuring a fluid parameter. The sensor comprises a sensing part for supplying a measurement data signal and a processing part releasably connected to the sensing part. The processing part comprises an identification recognition means capable of recognizing a presence of an identification means in the sensing part. Accordingly in the sensor a particular sensing part used may be recognized so that full functionality can be maintained when exchanging a recognized sensing part and more limited functionality is available when the sensing part is not recognized.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: August 16, 2022
    Assignee: YOKOGAWA PROCESS ANALYZERS EUROPE B.V.
    Inventors: Teunis Both, Ralph Richard de Leede
  • Patent number: 11364341
    Abstract: Systems and methods for delivering a medication to a person experiencing an emergency medical event without requiring intervention or action on the part of the person. A device encases a reservoir of medication and a delivery mechanism. Sensors in the housing sense a physical attribute of the person and circuitry monitors information collected by the sensors to determine if the person is experiencing a severe medical condition or event based on the information. An input device on or in the housing, such as a button, may be used or activated by the person if the detected condition or event is a false positive to cancel further action. If the system does not include the button or if the user does not press it in time, the system activates the delivery device and injects the medication into the person.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: June 21, 2022
    Assignee: INSULET CORPORATION
    Inventors: Robert Rioux, David Nazzaro
  • Patent number: 11358139
    Abstract: A blood sample collection and/or storage device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect the sample for storage and optionally process the sample within the housing. The housing may also be opened to access the stored sample for further processing.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: June 14, 2022
    Assignee: WEAVR HEALTH CORP.
    Inventor: Brandon T. Johnson
  • Patent number: 11351403
    Abstract: A band of stretchable material has dimensions suitable to be stretched over the neck of a urinal bottle. The neck has exposed edges that can come into contact with a user's hand, arms, male member, and/or any other portions of a user's anatomy, and the band is sized so that it covers those edges of the bottle neck. The band has a length and a diameter, and that diameter is smaller than the diameter of the neck in a urinal bottle. That way, when stretched over the neck, the bank will cover the edges of the neck of the bottle. In use, the band will also cover at least some portion of the opening in the neck of the urinal bottle.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: June 7, 2022
    Inventor: Patricia C. Sands
  • Patent number: 11311406
    Abstract: A fecal management device, and methods for applying a fecal management device to a patient, are described herein. In some embodiments, the fecal management device comprises a sheath having a first end and a second end, a first connector at the first end of the sheath, said first connector comprising a substrate that includes a first adhesive and a second adhesive, the second adhesive disposed relatively outwardly with respect to the first adhesive, the substrate having a multi-lobed contour with two opposing concave regions, a sheath port located at the second end of the sheath, the sheath port configured to removably mate with a collection bag port, and a collection bag, wherein the collection bag includes the collection bag port.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: April 26, 2022
    Assignee: Medline Industries, LP
    Inventors: Amanda Roszkowiak, Derrick Roemisch, Michael V. Turturro, Morgan Uridil
  • Patent number: 11298454
    Abstract: A wound treatment apparatus is provided for treating tissue damage, which comprises a fluid impermeable wound cover sealed over a site for purposes of applying a reduced pressure to the site. The apparatus also can include a cover with protrusions on its surface for purposes of monitoring pressure at the site. One or more sensors can be positioned under the cover to provide feedback to a suction pump controller. The apparatus can have a miniature and portable vacuum source connected to the wound cover.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: April 12, 2022
    Assignee: Smith & Nephew, Inc.
    Inventor: Richard Scott Weston
  • Patent number: 11285077
    Abstract: A blood collection device including a flow path to flow blood by capillary action capable of collecting a large amount of blood is provided. The blood collection device includes an introduction inlet 23 for introducing the blood of the subject M, a substrate 20 connected to the introduction inlet 23 and including a flow path 25 to flow the blood by capillary action, and a cooling body 30 for cooling the flow path 25.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: March 29, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Ayato Tagawa, Junko Kojima, Nobuyasu Hori, Kenji Akama, Masaya Okada, Kunpeng Cai, Samiko Hosoya, Shigeki Iwanaga
  • Patent number: 11278225
    Abstract: A pen format liquid collection device includes an elongate generally tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end, and at least one liquid take-up element (30, 130, 230, 330) mounted in the housing so as to be positioned or positionable to project at the opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed. At least one retention element (230a, 330a) is supported in the housing. The at least one liquid take-up element and the at least one retention element are arranged whereby they are relatively movable into contact, and the at least one retention element is adapted on contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing. The liquid take-up element is preferably a capillary.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: March 22, 2022
    Assignee: University of Tasmania
    Inventors: David Charles Bailey, Andrew Gooley, Florian Germain Lapierre, David John Melville, Rod Anthony Wiebenga, Chau Hoang Thanh Nguyen, Eugen Meyer
  • Patent number: 11278658
    Abstract: A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system housed within or above a wound dressing member. The micropump system includes a miniature pump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed without the need for a cumbersome external vacuum source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used. The patient does not need to be constrained for any period of time while exudate is being removed from the wound.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: March 22, 2022
    Assignee: Smith & Nephew, Inc.
    Inventors: Kurt Haggstrom, Alain Tranchemontagne, Loredana Jinga
  • Patent number: 11278219
    Abstract: Devices for collecting and analyzing a fluid sample comprise a fluid-collecting porous material comprising at least one hydrophilic porous layer and one or more sensors adapted to provide a response to the presence of an analyte. The detectors are useful for collecting and analyzing a very small volume of sample and may include features that facilitate and direct flow of the sample through porous material.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 22, 2022
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Paul D. Gassler, Austin J. Crouse, Sean R. Coyer
  • Patent number: 11266522
    Abstract: The present disclosure relates in general to a malleable and non-absorbent pessary having a solid cylindrical body formed of wax for use in improving symptoms associated with pelvic organ prolapse.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: March 8, 2022
    Inventor: Sally Ann Meyer
  • Patent number: 11241174
    Abstract: A wearable monitoring system includes a first flexible substrate encapsulating a current ramping system to provide a current to an electrode in direct contact with a predetermined location of skin of a user to promote bodily fluid secretion, and a second flexible substrate placed over the predetermined location, the second flexible substrate having an integrated electrochemical sensor to determine bodily fluid concentration levels secreted through the skin.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: February 8, 2022
    Assignee: International Business Machines Corporation
    Inventors: Bruce B. Doris, Sufi Zafar
  • Patent number: 11241252
    Abstract: Surgical access stabilization devices, systems, and methods are disclosed herein. For example, the devices, systems, and methods disclosed herein can be used during a surgical procedure to selectively establish, stabilize, and maintain a desired trajectory and/or positioning of a surgical access device. An exemplary surgical access stabilization device can include a pad with an adhesive distal facing surface to adhere to an anchor surface, a surgical access device coupled to the pad, and a locking mechanism to selectively lock a position of the surgical access device relative to the pad. In one embodiment, the anchor surface can be the skin of a patient. An exemplary surgical access device stabilization method can include making an incision in a patient at a surgical site, inserting a surgical access device through the incision, adhering a pad to an anchor surface, e.g.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: February 8, 2022
    Assignee: MEDOS INTERNATIONAL SARL
    Inventors: J. Riley Hawkins, Christopher Ramsay, Thomas Gamache, Eric Buehlmann
  • Patent number: 11234763
    Abstract: A method of ablating tissue comprising adjusting a set of dosing parameters for an ablation catheter based on a set of optical image-derived parameters generated from optical image-derived information obtained from direct optical imaging of the tissue while the ablation catheter is in contact with the tissue. The set of optical image-derived parameters may include a color profile, a blanching parameter, or a contact angle of a distal tip of the ablation catheter. The method may further comprise comparing the color profile to a signature profile and adjusting the set of dosing parameters based on the comparison between the color profile and the signature profile.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: February 1, 2022
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: John B. Allison, Celina Escobedo, Jean-Luc Pageard, Brian Pedersen
  • Patent number: 11234626
    Abstract: An apparatus includes a housing, defining an inner volume, and an actuator mechanism movably disposed therein. The actuator mechanism is configured to be transitioned from a first configuration to a second configuration to define a pre-sample reservoir fluidically couplable to receive a pre-sample volume of bodily-fluid via an inlet port of the housing. The actuator mechanism is movable from a first position to a second position within the housing after the pre-sample reservoir receives the pre-sample volume such that the housing and the actuator mechanism collectively define a sample reservoir to receive a sample volume of bodily-fluid via the inlet port. The outlet port is in fluid communication with the sample reservoir and is configured to be fluidically coupled to an external fluid reservoir after the sample volume is disposed in the sample reservoir to transfer at least a portion of the sample volume into the external fluid reservoir.
    Type: Grant
    Filed: June 13, 2016
    Date of Patent: February 1, 2022
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Shan E. Gaw, Jay M. Miazga, Shannon E. Eubanks, Richard G. Patton
  • Patent number: 11213667
    Abstract: A 3D printed biocompatible drug delivery device is provided having a fluid delivery channel distinguishing three segments and a receiving chamber with an array of microneedles. The three segments of the delivery channel are stagnation zones before a drug is extruded and whereby an inverted funnel provides an increasing extrusion surface servicing the drug to the array of microneedles. The design of the device with its flow-related components circumvents the challenge of colloidal stability associated with multi-phase formulations leading to nozzle blockage. Qualitative screening cytotoxicity tests pre and post-extrusion through the drug delivery device using mammalian cells rule out cytotoxicity and outline equivalent viability to control treatments. The biocompatibility results suggest that the fluid delivery design, the photoresin selected as well as the fabrication and sterilization may be extended over a range of regenerative medicine and drug delivery applications.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: January 4, 2022
    Assignee: Santa Clara University
    Inventors: Maryam Mobed-Miremadi, Chantell Farias, Cecilia Hemingway, Roman Lyman
  • Patent number: 11179083
    Abstract: The design and structure of a physiological fluid collection bag with instant data transmission capabilities, utilizing a micromachined thermal time-of-flight flow sensor as well as integrated pH and calorimetric mass flow sensors for simultaneous and continuous measurement of the instant volumetric flow rate, accumulated total volume, pH and density of data of a collected fluid is disclosed in embodiments. The fluid collection bag includes a collection chamber and storage chamber wherein the sensors are installed inside the storage chamber of the bag and the bag is fully disposable. The fluid collection bag is able to measure the flow rate and instantly relay the data to a reusable data processing unit that can transmit the data to a designated data center or to medical staff.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: November 23, 2021
    Assignee: Siargs Ltd.
    Inventors: Liji Huang, Chih-Chang Chen
  • Patent number: 11178961
    Abstract: A toothbrush device having a body defining a cavity and an input port disposed on the body in fluid communication with the cavity. The input port permits brushing by-products to pass through the input port and into the cavity while restricting passage of the brushing by-products outward from the cavity. In one form, the toothbrush device includes an elongated handle with a reservoir having at least a portion disposed within the handle. The reservoir is sized to hold a predetermined amount of oral care product, and a mouthpiece is in fluid communication with the reservoir to discharge the oral care product from the reservoir.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 23, 2021
    Assignee: Olson IP Technologies, Inc.
    Inventor: Richard Carl Olson
  • Patent number: 11172856
    Abstract: A system for uroflowmetry is disclosed. The system can include an audio device configured to obtain audio data of urination. The system can include a machine learning module with at least one processor and associated memory, wherein the system is configured to: process the audio data of urination via a machine learning model that is trained based on simulated urine flow data and associated audio data received from a urine flow simulator, and real urine flow data and associated audio data received from a urine flow measuring device, and output the processed audio data of urination to be used in uroflowmetry.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: November 16, 2021
    Assignee: Emano Metrics, Inc.
    Inventors: Bishara Charles Korkor, II, Alan Reid Hay, Edouard Alan Hay
  • Patent number: 11172866
    Abstract: The systems and methods described herein combine both moisture and electromyograph (EMG) sensors in a single wearable garment, along with a suitable output device such as a “smart” mobile device or computer, to provide users with new and useful feedback that can significantly improve incontinence symptoms. The EMG provides feedback to the user specifically regarding the quality of pelvic floor muscle contractions, while the moisture sensor provides feedback about the “end result” of the subjects' incontinence. Each measurement device alone can also provide useful information and feedback to different population groups. Combining these two measurements provides unprecedented data to enhance the subjects' therapy in managing urinary incontinence.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: November 16, 2021
    Assignee: Children's Medical Center Corporation
    Inventors: Jeanne Chow, Carlos Estrada, Michael K. Dempsey
  • Patent number: 11166658
    Abstract: This disclosure relates to a system and method for drawing blood from a user by skin puncture instead of venous puncture and storing it for analysis. The system includes a receptacle configured to engage an area of skin of the user at a blood draw location and store blood drawn from the user; a lancet device disposed within the receptacle configured to puncture the skin of the user at the blood draw location; a vacuum device configured to reduce a pressure within the receptacle such that the skin at the blood draw location is drawn into the receptacle before the lancet device punctures the skin, and to enhance blood flow while blood is drawn from the user; and a housing configured to house the receptacle, the lancet device, and the vacuum device. The receptacle, the lancet device, and the vacuum device may be modular and removably coupled with the housing.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: November 9, 2021
    Assignee: INVITAE CORPORATION
    Inventors: Sean Emerson George, Nathan McDonald, Eric Olivares, Robert Evans
  • Patent number: 11161117
    Abstract: Apparatus (2) for testing a liquid specimen, which apparatus (2) comprises: (i) a container (4) for the liquid specimen; (ii) a lid (6) for closing the container (4) after the liquid specimen has been provided in the container (4); (iii) first securing means (8) by which the lid (6) is secured to the container (4); (iv) a test capsule (10) for securing to the lid (6) when the lid (6) is on the container (4); (v) second securing means (12) by which the test capsule (10) is secured to the lid (6); and (vi) a response chart (14) which is operable in response to contact with the liquid specimen, and the apparatus (2) being such that: (vii) the lid has an openable portion (18) which when opened permits a liquid specimen in the container (4) to enter the test capsule (10); (viii) the test capsule (10) has opener means (20) for opening the openable portion on the lid (6) when the test capsule (10) is secured to the lid (6); and (ix) the response chart (14) is inside the test capsule (10) and is contacted by the liqu
    Type: Grant
    Filed: October 10, 2015
    Date of Patent: November 2, 2021
    Assignee: Clever Medical Limited
    Inventor: Oliver Blackwell
  • Patent number: 11134875
    Abstract: A specimen transfer device adapted to receive a blood sample is disclosed. The specimen transfer device includes a housing and an actuation member. A deformable material is disposed within the housing and is deformable from an initial position in which the material is adapted to hold the sample to a deformed position in which at least a portion of the sample is released from the material. A viscoelastic member is disposed within the housing between the material and the housing and between the material and the actuation member. The viscoelastic member is engaged with the actuation member and the material such that movement of the actuation member from a first position to a second position deforms the material from the initial position to the deformed position.
    Type: Grant
    Filed: January 20, 2020
    Date of Patent: October 5, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Milan Ivosevic, Bradley M. Wilkinson, C. Mark Newby, Kishore K. Bokka Srinivasa Rao
  • Patent number: 11129599
    Abstract: Apparatus and methods are described for use with a bodily emission of a subject that is disposed within a toilet bowl. While the bodily emission is disposed within the toilet bowl, light is received from the toilet bowl using one or more light sensors. Using a computer processor, one or more spectral components within the received light that are indicative of light absorption by a component of erythrocytes are detected, by analyzing the received light. In response thereto, the computer processor determines that there is a presence of blood within the bodily emission. The computer processor generates an output on an output device, at least partially in response thereto. Other applications are also described.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: September 28, 2021
    Assignee: OUTSENSE DIAGNOSTICS LTD.
    Inventor: Ishay Attar
  • Patent number: 11129570
    Abstract: Provided are devices and methods suitable for immobilizing tissue and for use in non-invasive methods of assessing lower urinary tract symptoms as well as in surgical application.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: September 28, 2021
    Assignee: BioFluid Technology, Inc.
    Inventors: Reuben E Kron, Stephen J Kron
  • Patent number: 11071527
    Abstract: A container assembly for biopsy including: a container provided with a lower chamber filled with a liquid intended to preserve biopsic samples and an upper chamber, a partition disposed in the upper chamber and provided with a base wall connected to the container; the partition has a lateral wall that raises from the base wall in such a way to define a compartment intended to receive a biopsic sample; disengageable connection means connect the base wall of the partition to the container; a cover is coupled with the container and cooperates with the lateral wall of the partition in such a way to push the partition, to force the disengageable connection means and to cause the disengagement of the base wall of the partition from the container.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: July 27, 2021
    Assignee: MECCANICA G.M. S.R.L.
    Inventor: Marco Bartelucci
  • Patent number: 11058453
    Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: July 13, 2021
    Assignee: KCI LICENSING, INC.
    Inventors: Benjamin A. Pratt, Christopher Brian Locke, Timothy Mark Robinson, Kevin Higley, Tab Randolph, T. Blane Sanders
  • Patent number: 11035872
    Abstract: A microfluidic flow controller for receiving analyte fluid and calibration fluids wherein the flow controller is configured to switch between (i) an analysis mode in which analyte fluid is passed to an analysis module and (ii) a calibration mode in which the analyte fluid is passed to an alternative destination and calibration fluid is passed to the analysis module, thereby maintaining flow rate of analyte fluid from a source and maintaining a steady flow rate of fluid through the analysis module in both analysis mode and calibration mode. The flow controller may vary the ration of multiple calibration fluids during a calibration mode. Means for accurately positioning sensors within a flow conduit of the analysis module is also described. Sensors are also described for use with or without the microfluidic flow controller for the detection of metabolites and molecules. The sensors may or may not comprise enzymes and may be used with a sensing reagent, also described.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: June 15, 2021
    Assignee: IP2IPO Innovations Limited
    Inventors: Martyn Gordon Boutelle, Michelle Louise Rogers, Chi Leng Leong, Sally Gowers
  • Patent number: 11038555
    Abstract: One example system for enabling NFC communications with a wearable biosensor includes a biosensor applicator including a housing defining a cavity configured to receive and physically couple to a biosensor device, and to apply the biosensor device to a wearer; a first applicator coil antenna physically coupled to the housing and defined within a first plane; and a second applicator coil antenna physically coupled to the housing and defined within a second plane substantially parallel to and different from the first plane, the second applicator coil antenna positioned coaxially with respect to the first applicator coil antenna, wherein the first applicator coil antenna is configured to wirelessly receive electromagnetic (“EM”) energy from a transmitter coil antenna of a remote device and provide at least a first portion of the received EM energy to the second coil antenna; and a biosensor device including a biosensor coil antenna defined within a third plane substantially parallel to and different than the fir
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: June 15, 2021
    Assignee: VERILY LIFE SCIENCES LLC
    Inventors: William Biederman, Anil Kumar Ram Rakhyani, Louis Jung, Stephen O'Driscoll
  • Patent number: 10993708
    Abstract: A device for application onto incisions or wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, having a flat porous mesh elongated along a longitudinal axis and having an upper side and an opposing lower or wound facing side and a central portion in immediate vicinity of the axis; further having a plurality of pores and windows in said mesh, said windows substantially larger than said pores and arranged along said longitudinal axis in said central portion; a crosslinking or polymerization accelerator or initiator disposed in or on the mesh; and a pressure sensitive adhesive disposed on at least a portion of the lower surface of the mesh.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: May 4, 2021
    Assignee: Ethicon, Inc.
    Inventors: Julian Quintero, Leo B. Kriksunov, Elena Wolfe
  • Patent number: 10987038
    Abstract: A system for transdermal alcohol sensing to be worn near a skin surface of a user, including: an alcohol sensor; a microporous membrane; a housing coupled to the alcohol sensor and the membrane, defining a volume between the alcohol sensor and a first membrane side, and fluidly isolating the volume from a second membrane side opposing the first membrane side; an electronics subsystem electrically coupled to the alcohol sensor, operable to power and receive signals from the alcohol sensor; and a fastener operable to position the second membrane side proximal the skin surface.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: April 27, 2021
    Assignee: KHN Solutions, Inc.
    Inventors: Keith Harry Nothacker, Will Tammen, Imraan Aziz
  • Patent number: 10980520
    Abstract: A biological fluid sampling vessel may include a container portion having an opening and an interior for housing a urine sample therein. The vessel may further include a sampling portion that removably engages the container portion to close off the interior. The sampling portion may include a sampling wand configured for obtaining a sample.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: April 20, 2021
    Assignee: Green Panther, LLC
    Inventors: Matt S Green, Joseph Daniel Massam
  • Patent number: 10966641
    Abstract: The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: April 6, 2021
    Assignee: SENZIME AB (PUBL.)
    Inventors: Pernilla Abrahamsson, Robert Herz, Einar Pontén, Bjoern Glaesel
  • Patent number: 10962471
    Abstract: A micro-cavity holder has an upper surface and a lower surface with a major recess in a generally cylindrical configuration. The major recess has an exterior periphery. The micro-cavity holder has a central aperture with a cylindrical central region and a lower region. A probe has a generally cylindrical configuration with an upper section and a lower section. The upper section has an exterior periphery removably received in the major recess to removably couple the probe and the micro-cavity holder. Cylindrical openings extend axially through the upper and lower sections of the probe and terminate above in a central recess. A transparent member is removably positioned in the central recess for receiving and supporting bodily fluids.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 30, 2021
    Inventor: Fazal Fazlin
  • Patent number: 10912540
    Abstract: Bodily fluid indicator devices and methods are provided. Such devices and methods can effectively indicate whether the amount of bodily fluid being produced is within a measurable range. In an exemplary embodiment, a bodily fluid indicator device includes a substrate having a surface. Some portions of the surface are covered with a region of absorbent material and other portions of the surface are devoid of the absorbent material. A graduated scale or a reactive feature is printed on the absorbent material. The device is configured to indicate an amount and/or a composition a bodily fluid present on an area of a patient or subject.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: February 9, 2021
    Assignee: FISHBURNE MAY, LLC
    Inventor: Coty Fishburne, Jr.
  • Patent number: 10912506
    Abstract: An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: February 9, 2021
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Richard G. Patton, Jay M. Miazga, Shan E. Gaw
  • Patent number: 10881340
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: January 5, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Samuel M. Curry, Manuel L. Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson, Phillip Yee
  • Patent number: 10881342
    Abstract: An assembly for sampling bodily fluid, the assembly comprising a membrane penetration device comprising a membrane penetrating element for penetrating a bodily membrane to release a bodily fluid; and, a collector configured in a collection position to take up the released bodily fluid and retain the fluid for delivery to a test element.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: January 5, 2021
    Assignee: ATOMO DIAGNOSTICS PTY LIMITED
    Inventors: John Kelly, Richard Sokolov, Ian Fredrick Johnson, Ernesto Monis Hueso, Eric Siu, Melody Shiue, Kamman Law, Johannes Behrisch
  • Patent number: 10871428
    Abstract: A fluid sample collection card assembly in one embodiment is assembled by forming a tray assembly by supporting an absorbent layer configured to receive a fluid sample on a base portion, the base portion including a tray portion, by positioning the absorbent layer on an upper surface of a holder portion of the tray portion, the holder portion located beneath an upper surface of the tray portion, removably inserting the formed tray assembly into a tray assembly receiving cavity of a case through a mouth portion of the case, and closing, at least substantially, the mouth portion of the case with a faceplate portion of the base portion.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 22, 2020
    Assignee: Advance Dx, Inc.
    Inventor: Ned Bedrio
  • Patent number: 10863933
    Abstract: One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: December 15, 2020
    Assignee: Gauss Surgical, Inc.
    Inventors: Siddarth Satish, Ali Zandifar, Kevin J Miller
  • Patent number: 10856782
    Abstract: A health monitoring system comprises a housing, a test strip assembly, a lancet, a transparent cover, and a monitor. The test strip assembly is configured to detect concentration of the sample of the blood, using lancet. It also has multiple ways to test blood like a laser-based system and a wireless based blood measuring system. Further, it has a heart rate monitor system, blood pressure and weight measuring rechargeable straps, wireless systems for information exchange with other devices, two way communication systems, a flash light, a removable X-Ray lens system, an auto created individual profile system based on a multi-factor authentication system that is capable of automatic grouping of all test results or any data created by a user, auto retrieving from a remote computer server and auto installing on a device based on its limitations through onboard multi-factor authentications systems.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: December 8, 2020
    Inventor: Anand Kumar Chavakula
  • Patent number: 10827966
    Abstract: Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system. The articles and methods described herein may be useful for facilitating the filling of relatively small channels with a fluid, such as channels of a microfluidic device. The articles and methods may, for example, interface with a patient sample (e.g., a droplet of blood), or with a macroscopic fluid source such as a pipette or syringe. In certain embodiments, articles and methods described herein may increase the ease of collecting a fluidic sample from a patient, prevent or reduce spillage of the fluidic sample, reduce contamination of a fluidic sample, and/or prevent or reduce air from entering a fluidic sample or device compared to certain existing fluid collection devices.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: November 10, 2020
    Assignee: OPKO Diagnostics, LLC
    Inventors: Jason Taylor, Hardeep Singh, Matthew Dirckx
  • Patent number: 10823662
    Abstract: A special-purpose cuvette assembly with features that create a small, restricted volume to minimize bulk movements of liquid and minimize backscattering-induced broadening of light. The special-purpose cuvette assembly enables recording of Brownian movements of nanoparticles in a liquid when it is placed in a suitable optical device comprising a light sheet and an optical microscope attached to a video camera that is oriented in a direction perpendicular to the light-sheet plane.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: November 3, 2020
    Assignee: HORIBA INSTRUMENTS, INCORPORATED
    Inventors: Jan J. Tatarkiewicz, Faizan Masood
  • Patent number: 10814113
    Abstract: Devices and methods for delivering an ingestible medicament of a medicament tablet into the gastrointestinal tract of a user. A device according to the invention includes a vibrating ingestible capsule and a hollow medicament compartment housing. The vibrating capsule includes a housing, a vibrating agitator disposed within the housing, a power supply, and a control element. The hollow medicament compartment housing is associated with the housing of the capsule and includes at least one aperture. The hollow of the medicament compartment housing is configured to have the medicament tablet disposed therein. The aperture(s) are dimensioned to enable fluid communication the surrounding environment and the hollow.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: October 27, 2020
    Assignee: Vibrant Ltd.
    Inventors: Lior Ben-Tsur, Shai Molnar, Ronny Shabbat