Liquid Collection Patents (Class 600/573)
  • Patent number: 11071527
    Abstract: A container assembly for biopsy including: a container provided with a lower chamber filled with a liquid intended to preserve biopsic samples and an upper chamber, a partition disposed in the upper chamber and provided with a base wall connected to the container; the partition has a lateral wall that raises from the base wall in such a way to define a compartment intended to receive a biopsic sample; disengageable connection means connect the base wall of the partition to the container; a cover is coupled with the container and cooperates with the lateral wall of the partition in such a way to push the partition, to force the disengageable connection means and to cause the disengagement of the base wall of the partition from the container.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: July 27, 2021
    Assignee: MECCANICA G.M. S.R.L.
    Inventor: Marco Bartelucci
  • Patent number: 11058453
    Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: July 13, 2021
    Assignee: KCI LICENSING, INC.
    Inventors: Benjamin A. Pratt, Christopher Brian Locke, Timothy Mark Robinson, Kevin Higley, Tab Randolph, T. Blane Sanders
  • Patent number: 11035872
    Abstract: A microfluidic flow controller for receiving analyte fluid and calibration fluids wherein the flow controller is configured to switch between (i) an analysis mode in which analyte fluid is passed to an analysis module and (ii) a calibration mode in which the analyte fluid is passed to an alternative destination and calibration fluid is passed to the analysis module, thereby maintaining flow rate of analyte fluid from a source and maintaining a steady flow rate of fluid through the analysis module in both analysis mode and calibration mode. The flow controller may vary the ration of multiple calibration fluids during a calibration mode. Means for accurately positioning sensors within a flow conduit of the analysis module is also described. Sensors are also described for use with or without the microfluidic flow controller for the detection of metabolites and molecules. The sensors may or may not comprise enzymes and may be used with a sensing reagent, also described.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: June 15, 2021
    Assignee: IP2IPO Innovations Limited
    Inventors: Martyn Gordon Boutelle, Michelle Louise Rogers, Chi Leng Leong, Sally Gowers
  • Patent number: 11038555
    Abstract: One example system for enabling NFC communications with a wearable biosensor includes a biosensor applicator including a housing defining a cavity configured to receive and physically couple to a biosensor device, and to apply the biosensor device to a wearer; a first applicator coil antenna physically coupled to the housing and defined within a first plane; and a second applicator coil antenna physically coupled to the housing and defined within a second plane substantially parallel to and different from the first plane, the second applicator coil antenna positioned coaxially with respect to the first applicator coil antenna, wherein the first applicator coil antenna is configured to wirelessly receive electromagnetic (“EM”) energy from a transmitter coil antenna of a remote device and provide at least a first portion of the received EM energy to the second coil antenna; and a biosensor device including a biosensor coil antenna defined within a third plane substantially parallel to and different than the fir
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: June 15, 2021
    Assignee: VERILY LIFE SCIENCES LLC
    Inventors: William Biederman, Anil Kumar Ram Rakhyani, Louis Jung, Stephen O'Driscoll
  • Patent number: 10993708
    Abstract: A device for application onto incisions or wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, having a flat porous mesh elongated along a longitudinal axis and having an upper side and an opposing lower or wound facing side and a central portion in immediate vicinity of the axis; further having a plurality of pores and windows in said mesh, said windows substantially larger than said pores and arranged along said longitudinal axis in said central portion; a crosslinking or polymerization accelerator or initiator disposed in or on the mesh; and a pressure sensitive adhesive disposed on at least a portion of the lower surface of the mesh.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: May 4, 2021
    Assignee: Ethicon, Inc.
    Inventors: Julian Quintero, Leo B. Kriksunov, Elena Wolfe
  • Patent number: 10987038
    Abstract: A system for transdermal alcohol sensing to be worn near a skin surface of a user, including: an alcohol sensor; a microporous membrane; a housing coupled to the alcohol sensor and the membrane, defining a volume between the alcohol sensor and a first membrane side, and fluidly isolating the volume from a second membrane side opposing the first membrane side; an electronics subsystem electrically coupled to the alcohol sensor, operable to power and receive signals from the alcohol sensor; and a fastener operable to position the second membrane side proximal the skin surface.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: April 27, 2021
    Assignee: KHN Solutions, Inc.
    Inventors: Keith Harry Nothacker, Will Tammen, Imraan Aziz
  • Patent number: 10980520
    Abstract: A biological fluid sampling vessel may include a container portion having an opening and an interior for housing a urine sample therein. The vessel may further include a sampling portion that removably engages the container portion to close off the interior. The sampling portion may include a sampling wand configured for obtaining a sample.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: April 20, 2021
    Assignee: Green Panther, LLC
    Inventors: Matt S Green, Joseph Daniel Massam
  • Patent number: 10966641
    Abstract: The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: April 6, 2021
    Assignee: SENZIME AB (PUBL.)
    Inventors: Pernilla Abrahamsson, Robert Herz, Einar Pontén, Bjoern Glaesel
  • Patent number: 10962471
    Abstract: A micro-cavity holder has an upper surface and a lower surface with a major recess in a generally cylindrical configuration. The major recess has an exterior periphery. The micro-cavity holder has a central aperture with a cylindrical central region and a lower region. A probe has a generally cylindrical configuration with an upper section and a lower section. The upper section has an exterior periphery removably received in the major recess to removably couple the probe and the micro-cavity holder. Cylindrical openings extend axially through the upper and lower sections of the probe and terminate above in a central recess. A transparent member is removably positioned in the central recess for receiving and supporting bodily fluids.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: March 30, 2021
    Inventor: Fazal Fazlin
  • Patent number: 10912540
    Abstract: Bodily fluid indicator devices and methods are provided. Such devices and methods can effectively indicate whether the amount of bodily fluid being produced is within a measurable range. In an exemplary embodiment, a bodily fluid indicator device includes a substrate having a surface. Some portions of the surface are covered with a region of absorbent material and other portions of the surface are devoid of the absorbent material. A graduated scale or a reactive feature is printed on the absorbent material. The device is configured to indicate an amount and/or a composition a bodily fluid present on an area of a patient or subject.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: February 9, 2021
    Assignee: FISHBURNE MAY, LLC
    Inventor: Coty Fishburne, Jr.
  • Patent number: 10912506
    Abstract: An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: February 9, 2021
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Richard G. Patton, Jay M. Miazga, Shan E. Gaw
  • Patent number: 10881340
    Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: January 5, 2021
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Samuel M. Curry, Manuel L. Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson, Phillip Yee
  • Patent number: 10881342
    Abstract: An assembly for sampling bodily fluid, the assembly comprising a membrane penetration device comprising a membrane penetrating element for penetrating a bodily membrane to release a bodily fluid; and, a collector configured in a collection position to take up the released bodily fluid and retain the fluid for delivery to a test element.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: January 5, 2021
    Assignee: ATOMO DIAGNOSTICS PTY LIMITED
    Inventors: John Kelly, Richard Sokolov, Ian Fredrick Johnson, Ernesto Monis Hueso, Eric Siu, Melody Shiue, Kamman Law, Johannes Behrisch
  • Patent number: 10871428
    Abstract: A fluid sample collection card assembly in one embodiment is assembled by forming a tray assembly by supporting an absorbent layer configured to receive a fluid sample on a base portion, the base portion including a tray portion, by positioning the absorbent layer on an upper surface of a holder portion of the tray portion, the holder portion located beneath an upper surface of the tray portion, removably inserting the formed tray assembly into a tray assembly receiving cavity of a case through a mouth portion of the case, and closing, at least substantially, the mouth portion of the case with a faceplate portion of the base portion.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: December 22, 2020
    Assignee: Advance Dx, Inc.
    Inventor: Ned Bedrio
  • Patent number: 10863933
    Abstract: One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: December 15, 2020
    Assignee: Gauss Surgical, Inc.
    Inventors: Siddarth Satish, Ali Zandifar, Kevin J Miller
  • Patent number: 10856782
    Abstract: A health monitoring system comprises a housing, a test strip assembly, a lancet, a transparent cover, and a monitor. The test strip assembly is configured to detect concentration of the sample of the blood, using lancet. It also has multiple ways to test blood like a laser-based system and a wireless based blood measuring system. Further, it has a heart rate monitor system, blood pressure and weight measuring rechargeable straps, wireless systems for information exchange with other devices, two way communication systems, a flash light, a removable X-Ray lens system, an auto created individual profile system based on a multi-factor authentication system that is capable of automatic grouping of all test results or any data created by a user, auto retrieving from a remote computer server and auto installing on a device based on its limitations through onboard multi-factor authentications systems.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: December 8, 2020
    Inventor: Anand Kumar Chavakula
  • Patent number: 10827966
    Abstract: Articles and methods for collecting and/or facilitating transfer of fluids are generally provided. In some embodiments, an article comprises a fluid collection region for introducing a fluid, such as a sample (e.g., blood sample) or a reagent, into a fluidic system. The articles and methods described herein may be useful for facilitating the filling of relatively small channels with a fluid, such as channels of a microfluidic device. The articles and methods may, for example, interface with a patient sample (e.g., a droplet of blood), or with a macroscopic fluid source such as a pipette or syringe. In certain embodiments, articles and methods described herein may increase the ease of collecting a fluidic sample from a patient, prevent or reduce spillage of the fluidic sample, reduce contamination of a fluidic sample, and/or prevent or reduce air from entering a fluidic sample or device compared to certain existing fluid collection devices.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: November 10, 2020
    Assignee: OPKO Diagnostics, LLC
    Inventors: Jason Taylor, Hardeep Singh, Matthew Dirckx
  • Patent number: 10823662
    Abstract: A special-purpose cuvette assembly with features that create a small, restricted volume to minimize bulk movements of liquid and minimize backscattering-induced broadening of light. The special-purpose cuvette assembly enables recording of Brownian movements of nanoparticles in a liquid when it is placed in a suitable optical device comprising a light sheet and an optical microscope attached to a video camera that is oriented in a direction perpendicular to the light-sheet plane.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: November 3, 2020
    Assignee: HORIBA INSTRUMENTS, INCORPORATED
    Inventors: Jan J. Tatarkiewicz, Faizan Masood
  • Patent number: 10814113
    Abstract: Devices and methods for delivering an ingestible medicament of a medicament tablet into the gastrointestinal tract of a user. A device according to the invention includes a vibrating ingestible capsule and a hollow medicament compartment housing. The vibrating capsule includes a housing, a vibrating agitator disposed within the housing, a power supply, and a control element. The hollow medicament compartment housing is associated with the housing of the capsule and includes at least one aperture. The hollow of the medicament compartment housing is configured to have the medicament tablet disposed therein. The aperture(s) are dimensioned to enable fluid communication the surrounding environment and the hollow.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: October 27, 2020
    Assignee: Vibrant Ltd.
    Inventors: Lior Ben-Tsur, Shai Molnar, Ronny Shabbat
  • Patent number: 10799629
    Abstract: A system and method to irrigate a user's auditory canal. A fluid can be dispensed from a reservoir through a fluid path and out through openings of a delivery element into the auditory canal. A pump may be used to facilitate the process of dispensing the fluid. The fluid can be delivered to the user's auditory canal for a predetermined period of time. Such a time period may be user selectable. The discharge from the irrigation is removed from the user's auditory canal via a discharge port located on the delivery element. The discharge exits the delivery element and proceeds to a discharge reservoir via a discharge path. A vacuum may be used to generate a negative pressure to facilitate the removal of the discharge from the auditory canal.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: October 13, 2020
    Assignee: SafKan, Inc.
    Inventor: Aadil Diwan
  • Patent number: 10779920
    Abstract: This invention relates to a negative pressure irrigation system including one or more negative pressure irrigation needles sized for insertion into a canal of a tooth, each needle having a closed distal end and two suction inlet ports located opposite one another immediately proximal to the closed distal end. The needles are placed in communication with a dental vacuum system by way of a suction manifold. An irrigant inlet tube supplies irrigant from a irrigant container into a pulp chamber or a tooth. The irrigant inlet tube may include a tapered end designed to tightly fit into a lateral irrigant supply port previously drilled into the pulp chamber. A light-cure polymer seals the inlet tube and needles when in use.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: September 22, 2020
    Inventor: L. Stephen Buchanan
  • Patent number: 10773066
    Abstract: A method of making an access port, includes providing a port body defining a fluid cavity, positioning a septum over the fluid cavity, and securing the septum to the port body. The septum includes a lower portion having a first diameter, an upper portion joined to the lower portion at a juncture, the upper portion having a second diameter less than the first diameter at the juncture, and a plurality of palpation features joined to the upper portion. Each of the palpation features includes a first end adjacent a central axis of the septum, and a second end extending radially outward, overlapping the juncture.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: September 15, 2020
    Assignee: C. R. Bard, Inc.
    Inventors: Bret Hamatake, John G. Evans
  • Patent number: 10758169
    Abstract: A urine collecting and analyzing apparatus that mounts on a toilet. The apparatus has a housing that mounts to or is integrated into the rim of the toilet bowl and has an opening for access to the bowl. The housing has a collector compartment and a controller compartment. A collector cup fits under the collector compartment extends over the bowl in a retracted position and in a collecting position. When in the collecting position, the cup captures urine released by a user. The cup is connected to a measurement chamber by a transfer tube. The urine moves through the transfer tube from the cup to the measurement chamber to a predetermined threshold volume and level. A controller in the controller compartment reads sensors and transmits sensor data to a device for storage and display.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: September 1, 2020
    Inventors: Cheng Yang, Long Di, Longze Chen, Cao Dong
  • Patent number: 10751681
    Abstract: A mixing device, in particular for bone cement, in which at least two ampoules provided with a septum are pushed onto needles, in parallel to each other, for discharging the liquid.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: August 25, 2020
    Assignee: OSARTIS GmbH
    Inventors: Christoph Sattig, Stefan Deusser, Rike Anders-Wessel
  • Patent number: 10737012
    Abstract: Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can include a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface, an opposing second surface, a first side, and an opposing second side. The channel can extend along a longitudinal axis from a first end to an opposing second end. The first acoustic wave generator can be coupled to the first surface. The second acoustic wave propagating component can be coupled to the second surface. The first acoustic wave generator and second acoustic wave propagating component can be configured to generate a bulk standing acoustic wave in the channel.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: August 11, 2020
    Assignee: Biomet Biologics, Inc.
    Inventors: Michael D. Leach, Ned M. Hamman, David Abeskaron, Grant Cunningham, Randel Dorian, Richard Wood Storrs, Scott R. King
  • Patent number: 10729411
    Abstract: A smart toilet capable of monitoring excrement and urine comprises a toilet bowl, a toilet seat, a telescopic lifting device, an excrement sample collection device, an excrement specimen preprocessing device, an excrement sample detection and analysis device, a telescopic lighting and photographing device, and a smart terminal. The whole process of bowel movement can be monitored to observe the general characteristics of the excrement and the presence or absence of parasites or eggs and to weigh the excrement, thereby realizing the automatic collection of an excrement sample and the pretreatment of the excrement specimen to provide convenience for the hospital users.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: August 4, 2020
    Assignee: Xiamen Brana Design Co., Ltd.
    Inventor: Zhongtang Wang
  • Patent number: 10729465
    Abstract: An apparatus to protect the tissues, muscles and nerves of the female pelvic floor from trauma during vaginal childbirth, the apparatus having a softly expansible intravaginal component capable of insertion into a vaginal canal and under a fetal head while in either a folded or rolled up configuration and to unfold or unroll into a deployed configuration in the vaginal canal and under the fetal head, and a support component with a handle capable of attachment to the intravaginal component, of deploying and inflating the intravaginal, preferably with pressurized air or liquid, and further sized and shaped to provide support and stabilization to at least one from among a perineal, perianal, and anal region when maintained against a female perineal body and perianal region while attached to the intravaginal device that is deployed beneath the fetal head within the vaginal canal, or, in cases of obstructed vaginal childbirth, being subsequently detached, temporarily leaving in situ within the vagina the deployed,
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: August 4, 2020
    Assignee: PARTURA MEDICAL, INC.
    Inventor: Eric Max Heinberg
  • Patent number: 10709369
    Abstract: A needle assembly comprising a housing, a first needle hub provided by the housing, a first hollow needle portion mounted to the first needle hub and extending from the first needle hub in a distal direction. A second needle hub is provided by the housing. A second hollow needle portion is mounted to the second needle hub and extends from the second needle hub in a proximal direction, opposite to the distal direction, wherein a hollow flashback chamber is arranged within the housing between the first needle portion and the second needle portion. The flashback chamber communicates with the inner lumen provided within the first and second hollow needle portion and is connected to the atmosphere by a passage and wherein a filter is provided within the passage, which is designed such that it is permeable for air to pour out of the flashback chamber into the atmosphere.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: July 14, 2020
    Assignee: POLY MEDICURE LIMITED
    Inventor: Rishi Baid
  • Patent number: 10705486
    Abstract: The Magic Gluco Wrist Watch (MGW) is a time wrist watch with a capability to measure the blood glucose level. The fix watch clasp plays a role of a lancing device, and is attached to the end of a left strap of the MGW. The movement of a holding member from the left strap to a right strap causes new electric current test strip to be driven in to the test strip port. A test strip port is located in the lug. By opening the valve, the MGW turns from time watch into a blood glucose meter.
    Type: Grant
    Filed: October 11, 2015
    Date of Patent: July 7, 2020
    Inventor: Zahra Aboutalebi
  • Patent number: 10690572
    Abstract: The present disclosure relates to a specimen collection device comprising ventilation means for drying a collected specimen. The device further comprises a cassette into which the specimen collected is secured to maintain evidentiary chain of custody requirements while providing unobstructed access to a collected specimen for automated analysis. Methods of using the device are also provided.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: June 23, 2020
    Assignee: LABORATORY CORPORATION OF AMERICA HOLDINGS
    Inventor: Jangbir Sangha
  • Patent number: 10675126
    Abstract: A surgical guard configured to protect a patient's oral cavity during surgery is disclosed. The surgical guard includes a first arcuate wing comprising a first end and a second end and a second arcuate wing comprising a first end and a second end. A wing connector couples the first end of the first arcuate wing and the first end of the second arcuate wing. The first arcuate wing, the second arcuate wing, and the wing connector are configured to retract and insulate the lips and oral commissure of a patient during oral surgery.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: June 9, 2020
    Inventors: Chris Bohlman, Michael Cunningham
  • Patent number: 10674946
    Abstract: The disclosed invention provides a sweat sensing device configured with self-aligned sweat stimulation means to provide adequate sweat generation for continuous monitoring of sweat. The disclosed device includes one or more analyte-specific sweat sensors that self-align with sweat glands. In one embodiment, the sweat sensing device includes means to protect the self-aligning sensors from abrasion against the skin or device components. In another embodiment, the device includes prolonged sweat stimulation for the self-aligning sensors through diffusion of a sweat stimulating compound into the skin.
    Type: Grant
    Filed: December 18, 2016
    Date of Patent: June 9, 2020
    Assignee: Eccrine Systems, Inc.
    Inventors: Gavi Begtrup, Jason Heikenfeld
  • Patent number: 10668268
    Abstract: A medical connector for use in a fluid pathway. A valve member with sealing rings helps preclude undesired accumulation of fluid within the connector. A branched connector includes a fluid diverter extending away from a port of the branched connector. The fluid diverter is configured to divert fluid flowing through the branched connector and into a medical connector attached thereto, flushing a distal portion of the medical connector.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: June 2, 2020
    Assignee: ICU Medical, Inc.
    Inventors: David Nelson, Thomas F. Fangrow
  • Patent number: 10668225
    Abstract: According to the invention a safety device for a pre-filled syringe comprises a substantially cylindrical and hollow support body and a hollow needle shield slideably arranged relative to the support body. The support body comprises at least one resilient arm and the hollow needle shield or a needle shield assembly comprises at least one curved actuation ramp. The curved actuation ramp protrudes in a lateral direction (L) perpendicular to a central axis (A) of the safety device. The curved actuation ramp comprises a first lateral dimension (L1) at a proximal end of the needle shield and a second lateral dimension (L2) exceeding the first lateral dimension (L1) at a distal end of the needle shield. The resilient arm engages the curved actuation ramp when the needle shield is slid relative to the support body.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: June 2, 2020
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Gareth Roberts, Chris Ward, Matthew Ekman
  • Patent number: 10632318
    Abstract: An external charger for an implantable medical device (IMD) is disclosed including a three-axis magnetic field sensor at the center of a primary charging coil. The sensor first senses a magnetic charging field produced by the coil with no IMD present (vector A). The sensor then senses the field in useful operation when such field is being provided to the IMD (vector B). From these vectors, a vector C is calculated representing the magnetic field reflected from the IMD. Vector C can be used to determine a vector D, representing the position of the IMD in physical space relative to the external charger. Information comprising one or more volumes can be stored in the external charger, and compared with vector D to determine whether charger-to-IMD positioning will provide an adequate amount of power to the IMD, and/or to provide an indication of charger-to-IMD alignment.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: April 28, 2020
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventor: Thomas W. Stouffer
  • Patent number: 10618233
    Abstract: The invention is generally related to soft contact lenses which comprise a non-silicone hydrogel lens body and a hydrogel coating thereon. The non-silicone hydrogel lens body is composed of a hydrogel material which is free of silicone and comprises at least 50% by mole of repeating units of at least one hydroxyl-containing vinylic monomer. The hydrogel coating comprises a first polymeric material having first reactive functional groups and a hydrogel layer derived from a second polymeric material having second reactive functional groups, and the hydrogel layer is covalently attached onto the anchor layer through linkages each formed between one first reactive functional group and one second reactive functional group. The soft contact lens has a surface lubricity better than the lubricity of the non-silicone hydrogel lens body and has a friction rating of about 2 or lower after 7 cycles of manual rubbing, a water content of from about 10% to about 85% by weight and an elastic modulus of from about 0.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: April 14, 2020
    Assignee: Alcon Inc.
    Inventors: Yongxing Qiu, John Dallas Pruitt, Jared Nelson
  • Patent number: 10604924
    Abstract: A urinal includes a body having an interior portion and an exterior portion. The urinal has an analysis portal having a sensing part and an investigating part communicatively coupled to the sensing part. The sensing part has a display and at least one sensor. The investigating part is configured to authenticate a user when the user is proximate the body. The sensing part is configured to directly receive urine voided by a user.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: March 31, 2020
    Assignee: NEWTONOID TECHNOLOGIES, L.L.C.
    Inventors: Fielding B. Staton, David Strumpf
  • Patent number: 10598583
    Abstract: Compact devices are provided to measure hematocrit of a blood sample. These devices include first and second chambers that receive respective portions of a blood sample via respective filters. The material of the filters prevents passage of red blood cells while permitting passage of blood plasma. One of the filters has one or more holes to permit the passage of whole blood. Thus, when an example device is presented with a sample of blood, one of the chambers contains whole blood and the other contains blood from which the red blood cells have been filtered. Electrodes in each of the chambers can then be used to detect the impedances of the whole blood and the filtered blood, and the detected impedances can be used to determine a hematocrit of the sample of blood.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: March 24, 2020
    Assignee: Verily Life Sciences LLC
    Inventors: Eric Peeters, Benjamin David Krasnow
  • Patent number: 10596361
    Abstract: Provided are a transdermal absorption sheet capable of achieving control of the dissolution rate and suppression of diffusion of a drug, and a method of producing the same. A transdermal absorption sheet includes a sheet portion, and a plurality of needle-like protruding portions formed by a plurality of frustum portions arranged on the sheet portion and needle portions arranged on the frustum portions, in which at least one of the needle-like protruding portions has a cavity portion extending from the sheet portion to the frustum portion.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: March 24, 2020
    Assignee: FUJIFILM Corporation
    Inventor: Satoshi Wakamatsu
  • Patent number: 10555696
    Abstract: A device to maintain a user's vein in position includes at least two branches separated by a gap of width greater than the size of the vein. A positioner to position the branches around the vein. The device can additionally includes a heater to heat at least one branch and a controller to control the heater. The device can further include a cooler to cool at least one branch and the controller is configured to activate the cooler.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: February 11, 2020
    Assignee: BEE HEALTHCARE
    Inventors: Aliaume Breteau, Adrien Balp, Pauline Guyot, Arnaud Navarro, Maxime Sabouret
  • Patent number: 10517791
    Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system includes a prosthesis configured to be worn by an individual, including at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: December 31, 2019
    Assignee: Purdue Research Foundation
    Inventors: Matthew P. Ward, Pedro P. Irazoqui, Muhammad Abdullah Arafat
  • Patent number: 10478113
    Abstract: The present disclosure relates generally to using detected bladder events for the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction. A system includes a sensing device comprising a pressure sensor to directly detect a pressure within a bladder. The sensing device is adapted to be located within the bladder. The system also includes a signal processing device to: receive a signal indicating the detected pressure within the bladder; detect a bladder event based the detected pressure within the signal; and characterize the bladder event as a bladder contraction event or a non-contraction event. The characterization of the bladder event can be used in the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: November 19, 2019
    Assignees: THE CLEVELAND CLINIC FOUNDATION, CASE WESTERN RESERVE UNIVERSITY, THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS
    Inventors: Margot S. Damaser, Swarup Bhunia, Robert Karam, Steve Majerus, Dennis Bourbeau, Hui Zhu
  • Patent number: 10463290
    Abstract: A biological sample collection and storage assembly, including: at least one filtering component; and an absorbent storage component; wherein the at least one filtering component is configured to filter a received biological sample in fluid form containing free cells and other biological components to separate the free cells from the other biological components such that the other biological components flow to the absorbent storage component for subsequent testing or analysis.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: November 5, 2019
    Assignee: Axxin Pty Ltd.
    Inventor: William R. Hopper
  • Patent number: 10456170
    Abstract: The invention relates to a device for insertion into a vaginal passage or for accommodation of a penis during coitus, comprising a selectively permeable separating wall for the enrichment of X-chromosome-bearing spermatozoa or Y-chromosome-bearing spermatozoa, wherein the separating wall shows an increased permeability for X-chromosome-bearing spermatozoa or Y-chromosome-bearing spermatozoa.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: October 29, 2019
    Assignee: BluPink GmbH
    Inventor: Thorsten Pilgrim
  • Patent number: 10449739
    Abstract: The invention is generally related to soft contact lenses which comprise a non-silicone hydrogel lens body and a hydrogel coating thereon. The non-silicone hydrogel lens body is composed of a hydrogel material which is free of silicone and comprises at least 50% by mole of repeating units of at least one hydroxyl-containing vinylic monomer. The hydrogel coating comprises a first polymeric material having first reactive functional groups and a hydrogel layer derived from a second polymeric material having second reactive functional groups, and the hydrogel layer is covalently attached onto the anchor layer through linkages each formed between one first reactive functional group and one second reactive functional group. The soft contact lens has a surface lubricity better than the lubricity of the non-silicone hydrogel lens body and has a friction rating of about 2 or lower after 7 cycles of manual rubbing, a water content of from about 10% to about 85% by weight and an elastic modulus of from about 0.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: October 22, 2019
    Assignee: Novartis AG
    Inventors: Yongxing Qiu, John Dallas Pruitt, Jared Nelson
  • Patent number: 10449348
    Abstract: The present invention relates to devices and methods for treating, reducing and preventing adverse skin/scalp conditions and enhancing the topical application of a benefit agent. The devices are ultrasonic with transducers positioned at an angle other than 90° relative to the surface at which the ultrasound is to be applied.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: October 22, 2019
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Alexandru Paunescu, Jyotsna Paturi, Ying Sun
  • Patent number: 10433779
    Abstract: An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: October 8, 2019
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Richard G. Patton, Jay M. Miazga, Shan E. Gaw
  • Patent number: 10408815
    Abstract: One embodiment of the present invention provides an apparatus for analyzing substances included in a liquid. The apparatus includes an absorber for absorbing the liquid and a testing device separate from the absorber. The absorber includes a main body and a detachable strip embedded in the main body, and both the main body and the detachable strip absorb the liquid. The testing device includes one or more sensors positioned on a top surface of the testing device to provide information associated with the substances included in the liquid in response to the detachable strip being placed on the top surface of the testing device.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: September 10, 2019
    Assignee: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventors: Michael Kuniavsky, Siqi Wang
  • Patent number: 10398810
    Abstract: In various embodiments, a nasal aspirator has a suction device having an input port, a nasal aspirator tip having a first body portion and a second body portion that is releasably coupled to the first body portion. The second body portion has an input port that is in fluid communication with an output port that is formed on the first body portion. A hollow tube has a first end that is coupled to the suction device input port and a second end that is coupled to the first body output port. In some embodiments, the suction device is configured to be releasably attached to the body of a user via a strap and the nasal aspirator tip is configured to be grasped between two adjacent fingers on the user's hand while leaving at least two other fingers on the user's hand free to manipulate the head of a child on which the nasal aspirator is being used.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: September 3, 2019
    Assignee: BeeClear, LLC
    Inventors: Steven L. Goudy, Sudarsan Pranatharthikaran, Siddhant Kumar Chawla, Ankit Raghuram, Catherine Gu, Young Kyoung Kim, Suhaas Anbazhakan
  • Patent number: 10376617
    Abstract: A suspension device for a drainage container has, on a first side, a first fastening unit for mounting and fastening the drainage container on the suspension device. On a second side, a second fastening unit is present for mounting and fastening the suspension device on a rail. The first fastening unit is arranged in a first fastening part, and the second fastening unit is arranged in a second fastening part. The suspension device further comprises a weighing part with a weighing element, wherein the weighing part is connected or can be connected to the first fastening part and to the second fastening part so as to measure, with the weighing element, a relative displacement, such that a filling quantity of the aspirated body fluid in the drainage container can be determined.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: August 13, 2019
    Assignee: MEDELA HOLDING AG
    Inventors: Charles Giezendanner, Cornel Bächler, Hilmar Ehlert