Abstract: A blood sampling cartridge is attachable to and removable from an attaching part of a blood test apparatus that includes a housing. The attaching part is provided in one side of the housing. The blood sampling cartridge includes a holder, a blood sensor that is attachable to one end of the holder, a lancet that is movable inside the holder, a blood collection needle attached to one end of the lancet, and a guide provided on the lancet. The guide of the lancet is configured to latch with the holder after puncturing with the blood collection needle, such that the blood collection needle is prevented from projecting beyond the blood sensor.

Abstract: Methods and systems to prepare a sample, including a relatively small amount of a biological sample, and to mix the sample with preparation fluid stored in a device. The device may include multiple fluid chambers and a stepped plunger to force a fluid in at least one of the chambers into a sample receiving chamber and then to a storage chamber. Methods and systems disclosed herein may be implemented to collect and controllable mix a sample for analysis and/or storage.

Abstract: A housing and an internal mechanism including a blade, a dual-link drive mechanism, and a trigger. The blade is driven by the drive mechanism through a rotating and translating slicing motion that defines a sampling sequence, from a first retracted position to an extended position to a second retracted position. The dual-link drive mechanism includes a blade link arm coupled to the blade, a rotary drive link arm that drives the blade arm, a drive spring that drives the a rotary drive arm, and a cam-and-follower mechanism that guides the blade arm as it is driven by the rotary drive arm. The trigger is operable to release the dual-link drive mechanism to propel the blade through the sampling sequence. And a sterility cap protects the blade and prevents operation of the device prior to removal.

Abstract: A lancing device integrated with a sensing strip and method of making and using the same are provided. A lance and analyte sensing strip are combined in a single, preferably disposable, device. In a preferred embodiment, a slot is provided in a support member so the lance can be engaged by a lance driver and driven into the skin producing a bodily fluid sample from a wound. The sensing area of the sensing strip is adjacent to the wound location reducing dexterity requirements for patients.

Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

Abstract: A test magazine with two film strips (12, 14), which are joined to one another in a sandwich-like manner, can be wound up, and between which holding cells (16) for test elements are kept free. The test magazine also comprises a multitude of test elements (18, 20) each having a puncturing unit (18) for inserting into body tissue and a test unit (20) for being subjected to body fluid. To this end, the puncturing units (18) and test units (20) are placed in separate holding cells (16) whereby separating them from one another.

Abstract: A blood component measurement device has a puncturing unit provided inside a housing and having a puncture needle; a button unit for advancing and retreating the puncture needle; a contact mechanism coming into contact with the skin of a person to be measured; and a holder for displaceably holding the puncturing unit. The blood component measurement device also has an introduction section at the substantially center of a contact member. After the skin is punctured by the puncture needle provided at the substantially center of the mechanism, the introduction section introduces blood to testing paper when the contact member of the contact mechanism is displaced in a sliding manner along a guide member.

Abstract: A supply of lancets for a multi-use lancing device are carried by a tape and sequentially brought from a storage position to an activating position by advancing the tape around a bend. The lancets are non-circular in cross-section along their longitudinal lengths, and in their activating position they extend from the tape such that their sharp tips are available for lancing tissue. The carrying tape can be arranged in reel-to-reel format in a housing having a lancing opening. The lancets can be integral with the tape and activated to move the lancet through the lancing opening by moving the tape along its tape path or by translating a dedicated service loop of the tape. The lancets can also be independent from the tape and activated through the lancing opening by a separate lancing actuator. A test media can be included on the carrying tape and the housing can contain a sensor to yield an integrated lancing and testing device.

Abstract: A method may include collecting at least one analyte from within a body, ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and receiving the ejected at least one analyte outside the body. A system may include a means for collecting at least one analyte from within a body, a means for ejecting the collected at least one analyte from the body through at least one dermal layer of the body, and a means for receiving the ejected at least one analyte outside the body.

Abstract: A system for determining an analyte in a body fluid includes a magazine comprising two partial magazines, one including chambers containing analysis elements having a sample contact zone and a reagent system containing a reagent, whose reaction with the body fluid results in a change of a variable, and another including chambers containing puncturing elements having a tip having a capillary channel, which forms a fluid connection between the tip and a sample transfer zone of the puncturing element. The system may also include an analysis instrument having a puncturing drive for driving a puncturing element on a movement path, a mounting for receiving the magazine such that one chamber of the magazine at a time is located in a functional position, in which a puncturing element in the chamber can be moved by the puncturing drive, and a measuring and evaluation apparatus for measuring the change of the variable.

Abstract: A puncture instrument includes a needle assembly, a hub passage for axially guiding a hub, a needle passage communicating with the hub passage and having a distal end opening for allowing the tip end of a needle to project instantaneously therethrough, two arms having first junctions connected to the hub and inclined rearward in a direction away from the hub in an initial state, two push rods connected to second junctions of the arms and extending rearward, a button for pushing the push rods forwardly, and fulcrum members disposed more closely to the distal end than the arms for abutment against portions of the arms when the arms are moved. When the push rods are pushed forwardly by the button, the arms push the needle assembly forwardly, thereafter have portions thereof brought into abutment against the fulcrum members, and turn to pull the needle assembly rearward.

Abstract: The present invention includes a device and method used for automated sampling and measurement of blood analytes, such as blood glucose, from a subject patient. The blood sampling and measurement may be performed automatically by the device on a patient without requiring user intervention or supervision. The sampling and measuring device comprises a sensor unit operably attached to a replaceable cartridge. The replaceable cartridge provides a disposable body that contains a number of lancets and test strips used for collecting and analyzing a blood sample. The sensor unit contains an actuator and microcontroller that fires the lancet and collects blood sample data from the test strips. The blood sampling and measurement process may be initiated by an external controller or may be autonomously initiated in a specific interval. A further embodiment involves integration and use of the sampling and measurement device within an automated monitoring and treatment system.

Abstract: A lancet-sampler system is configured to automatically remove a protective cover from a lancet and automatically unpack a test pad just prior to use. This minimizes the risk of injury and reduces the chance of cross-contamination between the lancet and the test pad. The lancet defines a capillary groove for drawing body fluid from the incision via capillary action and a sample transfer opening for collecting the fluid from the groove. A carrier tape is coupled to the lancet. The carrier tape includes a test pad for analyzing the fluid. The tape is folded around the test pad to form an airtight package. The test pad is located at a position to align with the sample transfer opening when the tape is unfolded. The protective cover covers a portion of the lancet, and when the tape is pulled, the protective cover is automatically pulled from the lancet.

Abstract: A system is proposed for detection of at least one analyte in a body fluid, in particular for detection of blood glucose. The system is designed to generate a sample of the body fluid and to transfer at least some of the sample to at least one test element, in particular a test panel. The system is designed such that a time period between the generation of the sample and the application to the test element is less than 1 second, preferably less than 500 ms.

Abstract: A medical device system for comparing a cardiopulmonary signal to a brain signal. In one embodiment of the invention, a medical device system is provided that includes a brain monitoring element, respiratory monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a respiratory signal from the respiratory monitoring element. The processor is further configured to compare the brain signal to the respiratory signal. Methods of comparing a brain signal to a cardiopulmonary signal are also provided.

Abstract: A rotational safety syringe includes front and rear barrels rotatable with respect to each other for moving a needle holder towards the rear barrel and compressing a spring to separate a protective cover. The needle holder is fixed by an elastic press button on the needle holder and a press opening on the rear barrel. After a through hole of the front barrel is aligned with a using position, the elastic press button can be pressed to release the needle holder, and the spring can eject the needle holder towards the through hole of the front barrel to extend the needle out from the through hole of the front barrel and pierce the needle into the using position. When the spring is released, the needle holder and needle are pulled back to hide the needle into the front and rear barrels to prevent the used needle from being touched.

Abstract: The medical puncturing device (10) includes a housing (12) having a proximal end (18) and a distal end (16) and a skin puncturing assembly (14) within the housing. The skin puncturing assembly includes a movable carrier (50) and a skin puncturing element (52). The skin puncturing element is adapted to puncture the skin of a patient. The carrier is movable from a retracted position wherein a distal tip of the skin puncturing element is disposed within the housing, to a puncturing position wherein the distal tip is exposed to puncture the skin of the patient. The carrier is moved from the retracted position to the puncturing position upon radial deformation of the housing. An internal guide (42) may be provided within the housing for guiding the movement of the carrier from the retracted position to the puncturing position.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A disposable glucometer is disclosed which includes a testing region for receiving a test strip and electronic components to perform blood glucose monitoring, a cell phone interface for relaying test results to a monitoring station or server (which can be through a Bluetooth radio), and a multi-strip test strip holder. The glucometer includes a mechanism to automatically load test strips, one at a time, from the multi-strip test strip holder into the testing region, and a mechanism to eject the strip from the testing region after the test is complete. The test strip holder is preferably encased in a transparent material or otherwise includes a visual indicator so that the number of strips remaining strips and available for testing can be determined. In one embodiment, the entire unit is disposable, and is discarded when all of the strips have been used. In another embodiment, the test strip holder portion of the unit is removed and replaced with a new test strip holder which is loaded with test strips.

Abstract: A puncturing device, a blood testing device, and a puncturing method, in which the remaining number of times of puncturing and the remaining number of times of blood testing are displayed. A laser puncturing device (100) has a measuring section (153) for measuring electric power consumed by a single puncturing operation, a measuring section (154) for measuring the residual amount of battery power, and a measuring section (157) for measuring electric power consumed by a laser emission device (110). A calculating section (156) calculates the performable remaining number of times of puncturing based on the measured remaining amount of battery power and measured electric power consumption. A control section (15l) displays the calculated remaining number of times of puncturing on a display section (160).

Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

Abstract: An instrument for producing a sample of body fluid for analysis by piercing the skin with a lancing element having a piercing tip is disclosed. The instrument can comprise a housing and a lancing drive for driving a lancing element connected thereto in a puncturing movement. A pressure ring can surround a skin contact opening and can be adapted for pressing against the skin such that the skin can bulge into the skin contact opening for promoting expression of body fluid. The skin contact opening can have a circular opening with a diameter of at least about 3 mm and at most about 8 mm. The instrument can comprise a pressing force control device for controlling the pressing force between the pressure ring and the skin at the time of triggering the puncturing movement, to be at least about 3 N and at most about 8 N.

Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

Abstract: Analysis system for automatically performing a skin prick analysis by pricking the skin for producing a sample of body liquid and detecting an analyte contained in the sample. The analysis system comprises a magazine with a plurality of compartments each containing a lancing element and an analysis element, and a reusable hand-held instrument having a drive assembly. The drive assembly is adapted for driving at least the following movements by manually generated mechanical force: a coupling movement by which one of the lancing elements is coupled to the drive assembly; a puncturing and sample collection movement of one of the lancing elements contained in the magazine and coupled to the drive assembly; and a remaganizing movement by which the test element is transported back into the compartment of the magazine.

Abstract: A blood test apparatus wherein a blood collection needle and a blood sensor can be easily attached and detached so that a burden or pain of a patient can be relieved. More specifically speaking, a blood test apparatus wherein a holder, a lancet, a blood collection needle and a blood sensor are united together as a blood sampling cartridge that is detachably mounted to the apparatus body. When this blood sampling cartridge is attached, a plunger involved in the apparatus body holds the lancet and connectors involved in the apparatus body come into contact with the blood sensor. It is preferable that the contact points with the blood sensor of the individual connectors are located at intervals at the same angle centering on a definite point.

Abstract: A method of using fluid aspirates as vehicles for drug delivery by collecting a fluid aspirate such as synovial joint effusion, pleural effusion, pericardial effusion, or ascites from a patient and centrifuging the fluid aspirate to provide a supernatant and a sedimented material. The sedimented material can optionally be further purified. One or more factors such as cytokines, bone morphogenetic proteins (BMPs), pharmaceutical drugs and gene vectors are added to the sedimented material or supernatant, optionally also including a biologically compatible medium such as a bioabsorbable sponge, so as to provide a vehicle for the one or more factors for reintroducion into the patient.

Abstract: A lancing device is provided for use with a removable lancet. The lancing device includes a housing and a lancet carrier slidably disposed within the housing and adapted to receive the lancet. A user-actuated ejection slide is mounted to the housing to eject the lancet from the lancet carrier. A locking member is pivotally mounted to the housing. As the ejection slide moves forward, it rotates the locking member to block forward movement of the lancet carrier during ejection. The locking member is configured so that substantially all of the force exerted on it by the lancet carrier is transmitted to the housing via the pivotal mounting.

Abstract: Analyte monitoring devices and methods therefore are provided. The devices integrate various functions of analyte monitoring, e.g., sample acquisition and testing.

Abstract: A phlebotomy device includes a needle defining a lumen and having a proximal end portion and a distal end portion. The distal end portion includes a sharpened tip configured to pierce tissue. The phlebotomy device further includes a sensor disposed at least partially within the lumen. The sensor has a first state and a second state and is configured to transition from the first state to the second state upon exposure to blood at physiological temperature.

Abstract: A body fluid sampling device includes a housing, a penetrating member positioned in the housing and a test strip. A compliant front end is coupled to the housing. The compliant front-end includes a rigid member with an interior aperture to receive the body fluid from a wound site.

Abstract: A lancet wheel having a rim with a plurality of lancets extending radially inward from the rim is dropped in a circular frame having a plurality of spokes forming a plurality of chambers for facilitating drop-in assembly of the modular lancet wheel with the frame. A test ring having a plurality of test sections is assembled on the frame such that one test section is located adjacent each lancet to form an integrated cartridge. Each lancet includes a lancet tip defining a capillary groove sized to collect a body fluid sample from the incision via capillary action. The lancet tip exits the chamber to form the incision in skin, the capillary groove collects the body fluid sample, the lancet tip retracts into the chamber, and a portion of the lancet contacts the test section to transfer the sample from the capillary groove to the test section to analyze the sample.

Abstract: A test sensor packaging container for use in sensor instrument. The test sensor packaging container comprises a housing, a first foil cover, and a second foil cover. The housing has a plurality of test sensor containing regions. Each of the test sensor containing regions has a proximal end and a distal end and is adapted to contain a test sensor. The test sensor containing regions protrude radially outward from the center of the housing. The housing has a top portion and a bottom portion that are generally parallel. Each of the test sensors has a width direction and a thickness direction. The first foil cover is adapted to cover the top portion of the housing. The second foil cover is adapted to cover the distal end of the plurality of test sensor containing regions. A plane generally parallel to the width direction of each of the plurality of test sensors is generally perpendicular to the top and bottom portion of the housing.

Abstract: A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

Abstract: A supply of lancets for a multi-use lancing device are carried by a tape and sequentially brought from a storage position to an activating position by advancing the tape around a bend. The lancets are non-circular in cross-section along their longitudinal lengths, and in their activating position they extend from the tape such that their sharp tips are available for lancing tissue. The carrying tape can be arranged in reel-to-reel format in a housing having a lancing opening. The lancets can be integral with the tape and activated to move the lancet through the lancing opening by moving the tape along its tape path or by translating a dedicated service loop of the tape. The lancets can also be independent from the tape and activated through the lancing opening by a separate lancing actuator. A test media can be included on the carrying tape and the housing can contain a sensor to yield an integrated lancing and testing device.

Abstract: A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.

Abstract: A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. A support is provided with a plurality of openings. Each opening receives a penetrating member. Each tip of a penetrating member is uncovered during launch of a penetrating member by the penetrating driver member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

Abstract: A sensor and a lancet are integrated with each other. A thin strip-shaped sensor and a lancet are integrated so that the lancet moves in parallel, along a longitudinal direction of the sensor. A measuring device to which an integrated lancet and sensor is attached is provided with a function of driving the attached lancet.

Abstract: Analysis system for determining an analyte in a body fluid is presented. The system comprises a reusable analysis instrument and a magazine having a plurality of integrated sample acquisition and analyzing elements. Each element comprises a puncturing element and an analyzing element. A coupling unit couples the integrated sample acquisition and analyzing element to a drive. The magazine comprises a housing having a plurality of elongate neighboring chambers separated by two side walls running in a longitudinal. The chambers contain the integrated sample acquisition and analyzing element. The chambers have an exit opening allowing for the at least partial exiting of the puncturing element. The chambers of the magazine are accessible to a coupling element that can be formfitting coupled to the coupling structure of the puncturing element, when the puncturing element is in the chamber of the magazine and the magazine is located in a holder.

Abstract: A body fluid testing device includes a body member and a tissue penetrator carried by the body member. A test strip holder is carried by the body member, and a test strip is carried by the test strip holder. The test strip is capable of receiving a body fluid thereon and processing the body fluid into a form suitable for yielding test results relating to the content of the body fluid. The body member, tissue penetrator, test strip holder and test strip are designed for a single use and for disposal as a unit without disassembly.

Abstract: These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator. A user interface is configured to relay at least one of, penetrating member performance or a penetrating member setting.

Abstract: A tissue penetration device includes a penetrating member driver, a cartridge, and a plurality of penetrating members integrated with the cartridge. Each of a penetrating member is coupled to the penetrating member driver when advanced along a path into a tissue target. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.

Abstract: A device for sampling body fluid includes a housing having a sleeve at a forward end thereof which is displaceable in response to being pressed against a user's skin to trigger the firing of a lancet. After the lancet is removed from the incision, the sleeve is repeatedly pressed against the skin to depress a ring of body tissue in surrounding relationship to the incision to express body fluid outwardly through the incision. A pusher member is then actuated to push a capillary tube through a front end of the housing for drawing-in body fluid. The lancet is a disposable lancet which includes a body supporting a skin-lancing member and the capillary tube. The disposable lancet passes through an upper end of a lancet carrier when being installed or removed. The device cannot be armed until the disposable lancet is installed in the housing, because the capillary tube functions to push a safety device to a non-safety position.

Abstract: The invention relates to a device for removing body fluid with a puncture element that can puncture the skin of a body part. The device includes a housing structure for body fluids obtained from the skin puncture and a puncture drive for a back and forth movement of the puncture element. The duration of withdrawal movement is longer than the duration of the forward movement. The puncture drive is designed to withdraw the puncture element in a first withdrawal phase of the withdrawal movement with a maximum withdrawal speed of more than 0.02 m/s. A second retraction phase follows the first retraction phase. Body fluid is collected during the second retraction phase, which has a duration of between 0.3 and 0.8 seconds and/or a retraction speed of between 0.6 and 2 mm/s.

Abstract: A method of obtaining a body fluid sample for determining the concentration of an analyte in the body fluid sample comprises applying pressure to the skin of the user. The skin is stretched so as to create a tear in the skin such that the applied pressure causes the body fluid to flow from the tear. The body fluid flowing from the tear is collected. Disclosed is also a pressure member for applying pressure to and stretching skin in preparation for forming a tear in the skin.

Abstract: A syringe (12) having: a syringe body (18) in which a passage (28) for the circulation of fluid is defined, the circulatory passage (28) being extended by a main element (20) for fluidic connection to a complementary volume (13); and a movable piston (36) inside the syringe body (18), defining, with the syringe body (18), a chamber for the containment of fluid, opening out through the circulatory passage (28). The syringe body (18) defines a closed space in which the piston (36) is movably mounted. The piston (36) also defines in the closed space an auxiliary return chamber. The syringe body (18) defines a return passage (48) opening out into the auxiliary return chamber (46). The return passage (48) is extended by an auxiliary element (50) for connection to the complementary volume (13).

Abstract: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.

Abstract: The test strip stabilizes skin prior to incision by a lancet tip. The innovative test strip includes a pair of skin contacting tabs that apply pressure linearly to the skin to stretch the skin taut. Beneficially an incision by a lancet tip to an accurate depth can be formed on the taut skin. Moreover, pressure from the tabs is applied linearly to the skin which results in a higher ratio of pressure to surface that can be reached as compared to applying pressure laminarily to skin. Some manufacturing techniques of the skin contacting tabs include cutting or stamping through all of the layers and test area of the test strip to form these tabs. These techniques increase the manufacturing efficiency and cost savings associated with test strips and integrated lancet testing devices. Contamination from other sampling events is eliminated since the test strips are disposed of after each use.

Abstract: A body fluid sampling system is provided for use on a tissue site. In one embodiment, the system comprises a cartridge; a penetrating member driver; a plurality of penetrating members arranged in a radial configuration on the cartridge wherein sharpened distal tips of the penetrating members point radially outward; wherein an active one of the penetrating members may be operatively coupled to the penetrating member driver, the penetrating member driver moving the active one along a path out of a housing having a penetrating member exit, into the tissue site, stopping in the tissue site, and withdrawing out of the tissue site; and a plurality of analyte detecting members, wherein at least one of the analyte detecting members is positioned to receive fluid from a wound created by the active one of the penetrating members, wherein the detecting members are not pierced by the active one of the penetrating members.

Abstract: A body fluid sampling system is provided for use on a tissue site. In one embodiment, the system comprises a cartridge; a penetrating member driver; a plurality of penetrating members arranged in a radial configuration on the cartridge wherein sharpened distal tips of the penetrating members point radially outward; wherein an active one of the penetrating members may be operatively coupled to the penetrating member driver, the penetrating member driver moving the active one along a path out of a housing having a penetrating member exit, into the tissue site, stopping in the tissue site, and withdrawing out of the tissue site; and a plurality of analyte detecting members, wherein at least one of the analyte detecting members is positioned to receive fluid from a wound created by the active one of the penetrating members, wherein the detecting members are not pierced by the active one of the penetrating members.

Abstract: A sensor and a lancet are integrated with each other. A thin strip-shaped sensor and a lancet are integrated so that the lancet moves in parallel, along a longitudinal direction of the sensor. A measuring device to which an integrated lancet and sensor is attached is provided with a function of driving the attached lancet.