Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: A wound dressing provides a tenacious occlusive seal against the skin of a wearer, even in the presence of excessive blood or heavy perspiration. The preferred embodiment combines an adhesive backing layer with a hydrogel island providing superior hydrophilic gel adhesion. The product performs under extreme temperatures (i.e., 32-140° F.), and may be used to hold other dressings in place. The preferred embodiments are entirely translucent, and include a large pull-tab for easy removal. Two dressings may be packaged in a pliable re-sealable protective pouch, thereby forming a portable “kit.” Different “vented” embodiments are disclosed. A preferred structure includes a cover layer peripherally bonded to backing and hydrogel layers having a central aperture therethrough. The cover layer has one or more vent holes, and pressure is released through the central aperture and out the vent hole(s).

Abstract: The adhesive bandage consists of a support with one surface having pressure sensitive adhesive and a wound covering pad placed centrally on it, which are covered by two protective detachable tear away tabs. The tear away tab consists of a single layer over the adhesive surface of the support and becomes two layered over the pad region. The two layers are fused at the zone of fusion near the margin of the pad, but are otherwise free from each other. The layer close to the pad, called inner barrier layer, completely covers the pad area. The outer layer, also called grasping layer, partially covers the barrier layer and the pad, and is folded upon itself to give sufficient length. When the outer layer is grasped to pull apart the releasable tear away tabs the inner barrier layer prevents contact of the finger to the pad. As one pulls apart the tear away tabs the barrier layers unfold and prevent contact of the fingers with the wound and wound exudates, preventing cross contamination.

Abstract: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.

Abstract: A pressure sensitive adhesive composition includes 4-15 w/w % styrene-isoprene-styrene copolymer, 20-35 w/w % styrene-isoprene diblock copolymer, 4-15 w/w % tackifier, 6-18 w/w % paraffin oil, and 30-45 w/w % hydrocolloid. The size of the hydrocolloid is below 40 ?m.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: An elongated flexible base strip is constructed with a bottom surface coated with an adhesive material. The base strip is constructed with bridging links which are spaced along the inner edge of the base strip and extend outward therefrom. The base strip, is cut to a first length and aligned with the wound with the bridging links extending over the wound. A matching portion of base strip is cut to a second length and aligned with the wound with the bridging links opposing. The opposing links are drawn together to close the wound. Adhesive on the links holds the links to the opposite base strip.

Abstract: The present invention relates to compositions of cyanoacrylate monomer, a method of improving the viscosity and the curing speed with a single additive and a process of providing sterilized cyanoacrylate adhesive compositions for application in the medical field.

Abstract: A wound closure system having first, second and third adhesive pads with a pair of strap members fixedly secured to the first and third adhesive pads. The pair of strap members are slidably received within the second adhesive pad. When the third adhesive pad is displaced, the first and second adhesive pads are displaced toward each other to close the wound.

Abstract: The invention provides an adhesive support article for supporting a body part of a user. A single-sided stretchable adhesive tape blank is precut into a sheet having a central anchoring portion and a plurality of outwardly extending fingers. The sheet is marked with visual indicators to guide the user of the support article for applying the central anchoring portion onto a first exterior surface of the body part and for stretching the fingers before adhering them at a predetermined distance away from the central anchoring portion. The adhesive support article can also be provided in a support system with at least one corresponding body landmark article, providing further guidance for applying the support article to the desired body part.

Abstract: A medical dressing is used to dress and treat skin wounds such as burns, cuts or traumatic injuries, and a method for making the same. The medical dressing includes an auxiliary release paper which makes it convenient to separate a pressure sensitive adhesive sheet from a release paper and is very easily separated from the pressure sensitive adhesive sheet after application to a wound site, thus improving the convenience of use of the dressing, and prevents the contamination of the pressure sensitive adhesive sheet in the process of either separating the pressure sensitive adhesive sheet from the release paper or separating the auxiliary release paper, thus preventing the secondary bacterial infection of a wound site, and is not exposed to the outside so that the dressing has an improved appearance and is convenient to carry and store.

Abstract: The medical protective cover includes a semi-ovoid shell configured to cover a wound or intravenous site. The shell is attached to a patient's limb or extremity by a pair of adhesive tabs extending from longitudinal ends of the shell and a plurality of adjustable straps extending laterally from the shell. A plurality of ventilation holes longitudinally extend along lateral edges of the shell to allow passage of air for keeping the covered area dry. Each longitudinal end of the shell includes a pair of tubing ports to facilitate mounting and passage of IV infusion tubing to an IV catheter or cannula. The top of the shell also includes a selectively opened slot that permits passage of a needle for the administration or withdrawal of fluids through an access port of the catheter.

Abstract: A self-adhesive wound care product, including a backing layer having a self-adhesive coating, preferably a silicone-gel adhesive coating, the backing layer of the product comprising a first area in which the adhesive coating has a first thickness, and a second area along at least a portion of the edges of the product. The second area has an adhesive coating having a thickness, which is less than the first thickness and which gradually decreases in a direction towards the edge of the product, from a thickness which is substantially equal to said first thickness to a thickness of 0-0.05 mm; or the second area is substantially free from adhesive coating.

Abstract: A self-adhering carrier enables application of an adhesive bandage without contact between the bandage's adhesive and the skin.

Abstract: A device for protecting an area of skin of a human body includes a plate. The plate includes a first face covered by an external layer and a second face opposite the external layer. The second face is configured to be applied onto an area of skin to be protected. The plate also includes a protective part made of a polymer gel and at least one adhesive part made of a polymer gel. The protective part is configured to ensure mechanical protection of the area to be protected and the adhesive part is configured to come into contact with the skin. The adhesive part has an adhesive power greater than an adhesive power of the protective layer to hold the plate on the area to be protected.

Abstract: Switchable adhesives comprising a mixture, in proportions by weight, of 20% to 98% of an adhesive, 2% to 80% of curable molecules and 0.05% to 10% of photoinitiator. Preferably, the adhesive and curable molecules are mutually soluble when dry or the curable molecules and adhesive may be uniformly dispersed in each other. Preferably the amount of adhesive in the mixture is in the range 40% to 98% by weight, more preferably 60% to 95% by weight, even more preferably 70% to 85% by weight. Preferably the proportion of curable molecules in the mixture ranges from 2% to 60% by weight, more preferably 5% to 40% by weight, even more preferably 15% to 30% by weight. Preferably, the photoinitiator is present in the mixture in the proportions 0.5% to 5% by weight, more preferably 1% to 3% by weight. Such switchable adhesives are useful in medical dressings and other removable sheet products, and may be simply prepared by stirring the adhesive, the curable molecules and the photoinitiator together at room temperature.

Abstract: An improved wound care system is set forth. The system includes a wound care device having a first end and a second end. A fastener, adapted to extend to a desired length to selectively attach the device at an anchor, wherein the anchor is provided on a second end of the device is also provided. The fastener is sufficiently sized and formed of a suitable material to prevent the device from moving when secured to the anchor. In an embodiment, medicine is provided in a desired treatment area of the device. The medicine can be inserted via a medicinal delivery device by inserting the medicinal delivery device up to a stop on the medicinal delivery device into the wound care device.

Abstract: A medicated patch is provided which is covered with a liner that enables one to remove the liner unconsciously and readily without losing the initial stickiness of the medicated patch. The external medicated patch includes a backing, an aqueous adhesive drug-containing matrix that is spread substantially entirely over one surface of the backing, and a liner that is larger in size than the surface of the drug-containing matrix to which the liner is attached. The liner larger in size than the surface of the drug-containing matrix to which the liner is attached includes an unattached area that extends from the surface of the drug-containing matrix, or an unattached slack portion that projects upward from the surface of the drug-containing matrix at a position on the surface of the drug-containing matrix.

Abstract: An improved post-operative dressing for providing both breast and, notably, nipple reconstruction and which in particular establishes custom lateral supporting of the nipple annulus. A body is constructed of a medical grade silicone and exhibits a three dimensional shape adapted for placement over the reconstructed breast and an aperture defined by an inner rim configured within the body is adapted to seat therethrough an associated nipple graft in a laterally supporting and non-pressure applied fashion. A number of secondary advantages incorporated into the body include each of apertures for breathability, suction/adherence properties, and impregnation or entrainment within the body inner surface of any form of anti-infection medicine.

Abstract: The invention relates to a thin film dressing having a release liner which is able to support the dressing during application. The resilience or stiffness of the release liner is higher than the resilience or stiffness of the dressing so as to enable the control of the dressing during application. The invention further relates to a method of application of the thin film dressing where a minor part of the dressing initially is applied to the skin afterwards the dressing is folded backwards so the release liner faces upwards. Finally, the remaining part of the dressing is applied by pushing the release liner forwards in a rolling motion thereby rolling the dressing onto the skin. This dressing assembly allows the dressing to be applied by using only one hand.

Abstract: A dressing suitable for topical application to the body, including a carrier substrate having a first side and opposing second side; and a layer of a foamed adhesive composition applied to the second side of the carrier substrate, where the layer of foamed adhesive composition includes a substantially homogeneous distribution of closed cells having an inert gas contained therein.

Abstract: This disclosure relates generally to adhesives and particularly to reversible adhesives. This disclosure further relates to generally adhesive articles and particularly to wound dressings comprising such adhesives. The adhesive comprises a core and a shell comprising at least two components. One of the components of the shell comprises a polymer formed by reacting a monomer of a thermally reversible polymer and the other component comprises a polymer formed by reacting a monomer of a polymer of a pressure sensitive adhesive. The wound dressing comprises a substrate and the reversible adhesive, forming a reversible wound dressing. Such wound dressings are particularly suitable for treatment of damaged sensitive tissue, for example wounds formed on a fragile skin.

Abstract: The invention provides wound dressings comprising an absorbent (porous) hydrogel composition comprising a foam portion which comprises a flexible plasticized hydrophilic polymer matrix having an internal cellular structure, and a continuous portion which comprises a flexible plasticized hydrophilic polymer matrix having relatively continuous internal structure. The continuous portion of the hydrogel composition includes apertures providing fluid flow communication through the continuous portion between an external surface of the continuous portion and the foam portion whereby the foam portion can take up external water or other fluid into the cellular structure through the apertures of the continuous portion. The continuous portion of the hydrogel composition may be tacky to the skin, allowing its use as a bioadhesive.

Abstract: A silicone adhesive composition including an ionic silicone and useful for healthcare applications such as wound care and drug delivery.

Abstract: Occlusive tissue dressings and methods including an elastomeric drape and a liquid component, at least partially cross-linked at least after one of drying and curing, suitable for application at a dressing-to-skin interface in order to create a substantially air-tight seal. The same or a different liquid component may be applied by a user at a tube-to-dressing interface in order to create a similar air-tight seal around the tube, if not occlusively sealed during its manufacture.

Abstract: Disclosed is a two-component device for closing a laceration or incision. The device includes a first component comprising a first adhesive-backed anchoring member and one or more first connecting members extending from one edge thereof in a first direction. Also included is a second component comprising a second adhesive-backed anchoring member and one or more second connecting members extending from one edge thereof in a second direction generally opposite to the first direction. Means for attaching the one or more first connecting members to the second anchoring member and means for attaching the one or more second connecting members to the first anchoring member is also provided. The attachment of the connecting members to the anchoring members forms attached and bridging portions of the one or more connecting members, the attached portions being attached to an anchoring member, and the bridging portions spanning the over-laceration area between the first and second anchoring members.

Abstract: In one embodiment, a selectively-releasable adhesive includes a base adhesive compound and a releasing compound that is blended with the base adhesive compound, the releasing compound being capable of decreasing the adhesive strength of the base adhesive compound when a releasing agent is applied to the selectively-releasable adhesive.

Abstract: The present invention relates to a pressure sensitive, hot melt processable adhesive composition comprising a polar plasticising oil, a polar polyethylene copolymer and polyisobutylene and a layered adhesive construction and a medical device comprising the adhesive composition according to the invention.

Abstract: A pad of elastomeric material having a softness of typically no more than about durometer 50 Shore 00. The pad may carry adhesive and/or a housing for adhering the pad to a surface, either manually, or by adhesive tape, or another strap. Such a pad exhibits hemostatic and leak prevention properties against needle puncture holes in the skin or the wall of a hollow medical device. Particularly, hemostasis may be prevented with low pressure application of the pad to the skin. The pad may be previously applied to the skin of the patient or a wall of a medical device such as tubing or a solution bag, and the needle may then penetrate both the pad and the skin or medical device wall, to make a resealable puncture with leakage reduction and hemostasis when the needle is withdrawn.

Abstract: The field of the invention is that of articles adhesive to the skin for medical or paramedical use. The invention relates to an article adhesive to the skin.

Abstract: A wound shield may include a conformable frame to circumscribe a wound. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing, allow compression for venous ulcers, retain moisture within the wound environment, absorb exudate, relieve pain and trauma associated with dressing removal, allow debridement and application of topical medications and or other compounds or chemicals, accelerate healing and facilitate monitoring of wounds. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site, to secure the frame to itself and or any suitable closure element and or to secure the dressing to the conformable frame. A wound shield may be used for humans or any suitable animal.

Abstract: Provided are medical articles (e.g., wound dressings) that include a pressure sensitive adhesive layer and methods of making the medical articles using immiscible materials that increase moisture vapor transmission rates.

Abstract: A self-sealing dressing (10) for application to skin of a human may include a substrate (12) including elastomeric material, and a cold flow adhesive layer (18) coupled to the substrate. The adhesive layer (18) may be adapted to adhere to skin of a human to form a substantially gas impermeable seal between the adhesive layer (18) and the skin that is maintained during repeated flexure and/or extension of the dressing. A maximum thickness of the combination of the substrate (12) and the adhesive layer (18) may be about 25 um.

Abstract: There is provided a gel sheet that has high biocompatibility and safety, can contain both a hydrophilic medicinal agent and a hydrophobic medicinal agent, and provides an excellent feel in use during the application onto human skin or others. A gel sheet including: a lipid peptide gelator including a low molecular weight lipid peptide having a molecular weight of 1,000 or less or a pharmaceutically usable salt of the lipid peptide; and a polymeric compound, wherein the polymeric compound is included in an amount of more than 1% (w/w) and less than 50% (w/w) with respect to the total mass of the gel sheet.

Abstract: A sacral wound dressing having a bottom end with three substantially V-shaped projections. In use, a protective layer of the wound dressing is removed to expose an adhesive layer and an absorbent layer, the wound dressing is folded over on itself substantially along a central axis, a medial V-shaped projection is inserted into a superior portion of the gluteal cleft of the person to adhere the medial projection to the skin within the gluteal cleft, two lateral V-shaped projections are then pushed against a superior portion of the buttocks of the person to adhere the lateral projections to the skin, and the opposing lateral ends and the top end of the wound dressing are then pushed against the skin of the person until the wound dressing is properly adhered to the sacrococcygeal region over the sacral wound.

Abstract: A wound shield including a conformable frame to circumscribe a wound and warm water circulating system to maintain a warm environment. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site and or to secure the dressing to the conformable frame.

Abstract: A pubic patch is provided to apply to the public area of a woman, particularly the mons pubis (Pubic Mound) area of the pelvic region. The pubic patch includes an adhesive base with a front side and a back side with decorative material attached to the front side, and the back side attached to human body. The pubic patch may further comprise fragrances and/or illuminating devices. The decorative material may be hairs attached to supporting sheet or LED material. Further, a products kit is provided which contains a plurality of pubic patches. The product kit may include an instruction booklet. A method of using the pubic patch is also provided comprises the steps of selecting a pubic patch and applying the pubic patch to the human surface in the pubic area.

Abstract: An article (1) of a medical and technical nature intended to be affixed to skin, or a component for affixing a medical article or part thereof to skin, which article or component comprises a layer of carrier material (2) that has a layer (3) of a soft skin-friendly adhesive on one side, and a protection layer (4) that protects the adhesive layer before use of the article or component and is affixed to the adhesive layer in such a way that it is releasable. According to the invention, the protection layer (4) is provided with a pattern of projections (6) on the side facing towards the adhesive layer (3) and a reinforcing layer (5) is arranged on the layer of carrier material (2), on the opposite side to the side that has the layer of soft skin-friendly adhesive, in such a way that it can be removed.

Abstract: Provided are buffered adhesive compositions comprising a high molecular weight polymeric buffer and products such as wound dressings and ostomy skin barriers incorporating the compositions.

Abstract: A wound dressing with a wound pad and a layer of vapor-permeable material arranged on top of the wound pad and extending peripherally outside the wound pad is described, wherein at least that part of the vapor-permeable layer extending peripherally outside the wound pad is coated with adhesive, and wherein the wound pad includes a liquid-retaining and liquid-transporting layer, and an upper distributing layer and lower distributing layer which bear against the top and underside, respectively, of the liquid-retaining and liquid-transporting layer.

Abstract: The present invention relates to a new bandage that can be easily removed from the packaging and applied to a patient while wearing gloves. Additionally, the bandage can be easily removed from the patient after it is no longer needed. In one embodiment of the invention, the bandage comprises an adhesive portion and non-adhesive portion such as a tab that the user can grab onto to either remove it from the packaging or remove it from the patient after it is no longer needed.

Abstract: A wound dressing product comprising: a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on said upper surface and on said lower surface; and upper and lower release sheets covering said substrate and said tacky silicone coating composition on said upper and lower surfaces, respectively, and adhered to said surfaces by said tacky silicone coating composition, wherein said upper surface is less tacky than said lower surface whereby said upper release sheet can be removed from said upper surface more readily than said lower release sheet can be removed from said lower surface. The same silicone composition is used to form both the upper and the lower surface. Also provided are methods for making such dressings.

Abstract: The present invention relates to a wound dressing which comprises a hydrocolloid adhesive mass comprising a hydrophobic elastomer matrix comprising poly(styrene-olefin-styrene) block copolymers, particles of hydrocolloid(s) dispersed in said elastomer matrix, and at least one tackifying hydrocarbon resin, characterized in that the hydrocolloid adhesive mass has a deformation ratio ? comprised between at least 0.10 and at most 0.40, as measured by subjecting a cylindrical sample having a diameter of 10 mm, of said hydrocolloid adhesive mass having a thickness of 1.0 mm, at a temperature of 37° C.

Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.

Abstract: A wound dressing having a thin barrier layer of soft, pliant adhesive material with a flexible cover layer extending along one side of the adhesive layer and a removable release sheet on the opposite side is disclosed. The adhesive material has a center and border surrounding the center such that the adhesive is contoured. A method for making the contoured dressing using a gear pump and a laminating roller having a predetermined softness and firmness is also disclosed.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a interlock woven fabric subjected to crimping processing, the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer, the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, and the methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.

Abstract: Provided herein is a system and method for facilitating removal of a drape from a tissue site. One aspect provides a system comprising a drape, and adhesive layer, and a release agent, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimulus. Another aspect provides a method for application and removal of a drape using less force than required with a conventional drape.

Abstract: Various systems, methods and materials are disclosed that enable efficient delivery of an agent into an adhesively adhered article, in which the agent elicits a desired outcome, on demand. This strategy, though general in scope, is also more specifically described with regard to enabling painless or atraumatic removal of products adhering to mammalian tissues such as skin and hair by suitably exploiting the ingress of an appropriate agent or like fluid. Other techniques and articles that aid in the handling or removal of such adhesive products are also disclosed.

Abstract: The present invention relates to a wound dressing which comprises a hydrocolloid adhesive mass comprising: a hydrophobic elastomer matrix comprising polystyrene-olefin-styrene) block copolymers, particles of hydrocolloid(s) dispersed in said elastomer matrix, at least two hydrogenated-hydrocarbon tackifying resins, the difference between the softening temperatures of a first hydrogenated-hydrocarbon tackifying resin and of a second hydrogenated-hydrocarbon tackifying resin comprised in the hydrocolloid adhesive mass being at least 10° C. and at most 40° C.