With Means For Cutting, Scarifying, Or Vibrating (e.g., Ultrasonic, Etc.) Tissue Patents (Class 604/22)
  • Patent number: 11684512
    Abstract: A vitrector for performing a vitrectomy comprises a tubular shaft portion which is attached to a distal end of a vitrector hand piece. The shaft portion is provided with a sharply pointed needle tip portion for piercing the pars plana and sclera of the eye, and a pneumatically driven guillotine cutter is incorporated within the shaft portion of the vitrector at a location immediately adjacent to the sharply pointed needle tip portion. A source of pneumatic air is operatively connected to the proximal end of the vitrector hand piece and is pneumatically connected to the guillotine cutter so as to drive the same. In addition, an aspiration line is also operatively connected to the proximal end of the vitrector hand piece and is also fluidically connected to the region immediately adjacent to the pneumatically driven guillotine cutter so as to remove the floater particles, severed from the vitreous cavity by means of the pneumatically driven guillotine cutter, by means of aspiration.
    Type: Grant
    Filed: March 8, 2020
    Date of Patent: June 27, 2023
    Assignee: Vista Ophthalmics, LLC
    Inventor: Jeffrey Whitsett
  • Patent number: 11678897
    Abstract: A surgical method treats infections on a lead positioned at least partially within a patient's body. The surgical method includes uncoupling the lead from a pulse generator. The lead is then coupled to an ultrasound wave generator. Ultrasound waves are propagated from the ultrasound wave generator through the lead. Systems are disclosed.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: June 20, 2023
    Assignee: MEDTRONIC, INC.
    Inventors: Alan Cheng, Jian Cao, Zhongping Yang
  • Patent number: 11679029
    Abstract: A vitrectomy apparatus is provided, including a disposable cutter that incorporates a linear voice coil motor to generate consistent and rapid guillotine action without the use of a rotary motor or traditional linear motor. The apparatus includes voice coil actuator to provide for a forward and backward reciprocating motion cutting blade.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: June 20, 2023
    Assignee: Johnson & Johnson Surgical Vision, Inc.
    Inventors: Scott G. Strayer, Lauren M. Hickey
  • Patent number: 11672524
    Abstract: Devices and methods for cutting a tether are described herein. Devices described herein generally comprise a proximal handle, a catheter, and an inner shaft and a cutting blade disposed within the lumen of the catheter, where the cutting blade is movably disposed over the inner shaft. The proximal handle comprises an actuation mechanism to control the movement of the components of the device. Methods described herein generally comprise advancing a tether-cutting device over a tether, loading the tether through the catheter and inner shaft, applying tension to the tether, and rotating and distally translating a cutting blade in order to cut the tether.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: June 13, 2023
    Assignee: Ancora Heart, Inc.
    Inventors: Russel Sampson, David Scott Baron, Rob Kotmel
  • Patent number: 11672557
    Abstract: A vibrating hand held surgical instrument for loosening tissue of a patient for liposuction or body contouring procedures. The instrument includes a motor connected to a vibration actuator having an eccentric rotating mass and an end effector for engaging tissue operatively connected to the vibration actuator, wherein the motor rotates the eccentric mass to cause the end effector to vibrate to loosen tissue. A flexible shaft having first end and second ends dampen the vibration to the motor and to the operator handle.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: June 13, 2023
    Assignee: LIPOCOSM, LLC
    Inventors: Roger K. Khouri, Khalil R. Khouri
  • Patent number: 11666378
    Abstract: The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: June 6, 2023
    Assignee: Neurent Medical Limited
    Inventors: David Townley, Brian Shields
  • Patent number: 11660162
    Abstract: An arthroscopic shaver cleaning device and method of cleaning an arthroscopic shaver blade/burr are disclosed. The arthroscopic shaver cleaning device includes a sleeve portion configured to interface with a proximal portion of a blade/burr of an arthroscopic shaver. The arthroscopic shaver cleaning device further includes a fluid connection portion having a fluid passageway configured to direct fluid toward the proximal portion of the blade/burr in order to dislodge debris entrapped in shaver lumen of the blade/burr.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: May 30, 2023
    Assignee: Mark 2 Medical, LLC
    Inventors: Mark Ritter, Mark Dale
  • Patent number: 11638624
    Abstract: A method for performing an endovascular procedure using ultrasonic energy includes providing a first sheath having a proximal end portion and a distal end portion, and having a first window in the distal end portion; positioning a wave guide in the first sheath for delivering the ultrasonic energy through the first window for performing the endovascular procedure; and selectively covering the first window with a cover.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: May 2, 2023
    Assignee: C.R. Bard, Inc.
    Inventor: Jessica Lynn Roll Hoye
  • Patent number: 11633176
    Abstract: Embodiments include devices, methods, and systems for positioning devices. An exemplary method comprises: moving a distal end of a tube into a body, the tube including a lumen and a shaft in the lumen, the shaft having a transducer; sending a first signal to the transducer; passing, with the transducer, in response to the first signal, a wave energy into the body; receiving, with the transducer, a reflected portion of the wave energy; generating, with the transducer, a second signal in response to the reflected portion of the wave energy; determining, with a processor, an indicia of the body in response to the second signal; and identifying, with the indicia, a targeted issue in the body; positioning the distal end of the tube at the targeted tissue in response to the indicia; and removing a portion of the targeted tissue with the distal end of the tube.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: April 25, 2023
    Assignee: Boston Scientific Scimed Inc.
    Inventors: Hong Cao, Dongming Hou
  • Patent number: 11622786
    Abstract: Disclosed herein is a medical device. The medical device includes an outer tubular member and an inner tubular member. The outer tubular member has a distal end, an open window disposed at the distal end, and one or more dimples. The inner tubular member has a distal tip and one or more axial grooves. The inner tubular member is configured to be received within the outer tubular member. The one or more axial grooves and the one or more dimples are configured to align the distal tip of the inner tubular member with the open window of the outer tubular member. The open window of the outer tubular member and the distal tip of the inner tubular member are configured to cut tissue.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: April 11, 2023
    Assignee: GYRUS ACMI, INC.
    Inventors: Kevin Edwards, Jay Casey, Joel Willhite, Ahmad Alsaffar
  • Patent number: 11611307
    Abstract: A short-circuit fault-tolerant control method based on deadbeat current tracking for a five-phase permanent magnet motor with a sinusoidal back-electromotive force or a trapezoidal back-electromotive force (EMF) is provided. By fully utilizing a third harmonic space of a five-phase permanent magnet motor in a fault state, the method proposes a fault-tolerant control strategy for a five-phase permanent magnet motor with a sinusoidal back-EMF or a trapezoidal back-EMF in case of a single-phase short-circuit fault. The method enables the five-phase permanent magnet motor to make full use of the third harmonic space during fault-tolerant operation, thereby improving the torque output of the motor in a fault state and improving the fault-tolerant operation efficiency of the motor. The method achieves desirable fault-tolerant performance and dynamic response of the motor, and expands the speed range of the motor during fault-tolerant operation.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: March 21, 2023
    Inventors: Qian Chen, Yuhang Xia, Licheng Gu, Wenxiang Zhao, Guohai Liu
  • Patent number: 11602258
    Abstract: An exemplary system includes a memory storing instructions and a processor communicatively coupled to the memory. The processor is configured to execute the instructions to receive, from a sensor of a surgical instrument, environmental condition information associated with the surgical instrument and detected by the sensor while the surgical instrument is disconnected from an external power source, the surgical instrument including circuitry configured to be powered and operate only while the surgical instrument is connected to the external power source, determine, based on the environmental condition information, an operational condition of the surgical instrument, and provide a notification indicating the determined operational condition of the surgical instrument.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: March 14, 2023
    Assignee: Intuitive Surgical Operations, Inc.
    Inventors: Quentin F. Polosky, Diana C. W. Friedman, Mathew D. Clopp, Yves Lacroix, John A Barton, Dean A. Mansour
  • Patent number: 11589854
    Abstract: The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: February 28, 2023
    Assignee: Corvia Medical, Inc.
    Inventors: David S. Celermajer, Edward I. McNamara, Michael W. Sutherland, Hiroatsu Sugimoto
  • Patent number: 11583261
    Abstract: A biopsy device includes a cylindrical hollow stylet having a proximal end, a distal end, and a uniform wall thickness. The proximal end and the distal end are disposed on the longitudinal axis. A longitudinal recess forms a sample chamber and is positioned adjacent the distal end of the cylindrical hollow stylet. A longitudinal insert has a longitudinal length, a distal terminal end, and an elongate channel. The longitudinal insert is positioned within the cylindrical hollow stylet with the distal terminal end proximal to the longitudinal recess. The longitudinal insert is immovably connected to the cylindrical hollow stylet. The elongate channel is configured to maintain a fluid passageway through the cylindrical hollow stylet from the proximal end to the longitudinal recess.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: February 21, 2023
    Assignee: C. R. Bard, Inc.
    Inventors: Tyson D. Anderson, Daniel O. Almazan, Dnyanesh A. Talpade
  • Patent number: 11576800
    Abstract: A surgical weight loss procedure to reduce stomach volume is provided. The procedure involves gathering together a quantity of stomach tissue and securing this tissue together in a gathered position, which can reduce the volume of the stomach. This reduced stomach volume allows a patient to feel satiated with a much smaller amount of food, leading to weight loss.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: February 14, 2023
    Inventor: Nassar Ismail
  • Patent number: 11564705
    Abstract: Disclosed herein is a medical device. The medical device includes two coaxially aligned solenoids and a cannulated armature configured to be received within the two coaxially aligned solenoids.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: January 31, 2023
    Assignee: Gyras ACMI, Inc.
    Inventors: David Church, Ahmad Alsaffar, Daniel Goldberg, Joel Willhite, Kevin Edwards
  • Patent number: 11535510
    Abstract: A sub-centimeter structure includes a first structural component, a second structural component arranged proximate the first structural component, and a joint connecting the first and second structural components. The joint includes a material that has a first phase that is substantially rigid to hold the first and second structural components in a substantially rigid configuration while the material is in the first phase. The material of the joint has a second phase such that the joint is at least partially fluid to allow the first and second structural components to move relative to each other while the material is in the second phase. The joint interacts with the first and second structural components while the material is in the second phase to cause the first and second structural components to move relative to each other. And, the first and second structural components include a polymer.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: December 27, 2022
    Assignee: The Johns Hopkins University
    Inventors: David H. Gracias, Anum Azam
  • Patent number: 11504089
    Abstract: An adaptor for adjusting electrical signals propagated along an electrically-conductive path between a drive unit and a catheter of an intravascular ultrasound imaging system includes a catheter connector disposed along a first end of a housing and configured to receive the catheter. A drive-unit connector is disposed along a second end of the housing and is configured to couple the adaptor to the drive unit. A catheter-conductor interface electrically-couples to a transducer conductor of the catheter. A drive-unit-conductor interface electrically-couples to an electrical conductor of the drive unit. An adaptor conductor electrically-couples the catheter-conductor interface to the drive-unit-conductor interface. A tuning element is electrically-coupled to the adaptor conductor and is configured to adjust electrical signals propagating along the adaptor conductor based, at least in part, on an operational frequency of a transducer disposed in the catheter.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: November 22, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Peter Thornton, Jr.
  • Patent number: 11504153
    Abstract: An improved plaque extractor for shaving, scooping, cutting, and emulsifying accumulated plaque from blood vessels into fine particles, and removing the particles from blood vessel walls without cutting or permanently stretching the walls, and without substantially blocking the blood flow through the vessel during plaque removal operation. The plaque extractor includes an extractor guide and an internal auger, in which both are rotating and moving axially inside the vessel to engage the occlusive material. The operation of the device does not substantially disrupt blood pressure within the blood vessel.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: November 22, 2022
    Assignee: MOST CARDIO, LLC
    Inventors: Victor Dardzinski, Pavel Menn
  • Patent number: 11490923
    Abstract: Disclosed herein is a device for disrupting material in a body vessel and a method for making such a device. The device includes a plurality of arms disposed circumferentially about an axis. Each arm includes two blades; one sharper, and one blunter. The sharper blades are all oriented in the same direction, clockwise or counterclockwise, such that when the device is rotated in a first direction, the sharper blades engage the material, and in the other, the duller blades engage the material.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: November 8, 2022
    Inventors: Keith Milner, Joshua Krieger
  • Patent number: 11478296
    Abstract: A medical device system for the delivery of energy to a region of a patient's anatomy is provided. An introducer tube defines a lumen therein and bears a first electrode. A second electrode is movable within the lumen between a retracted position and an extended position. In the retracted position, the second electrode is substantially disposed within the lumen. In the extended position, the second electrode extends at least partially beyond the distal end of the introducer tube. In one form, the introducer tube is configured to substantially hold the second electrode within the lumen in a predetermined orientation in the extended position, and the introducer tube prevents the second electrode from substantially rotating within the lumen of the introducer tube during movement into the extended position. In one form, the introducer tube is more flexible in a first plane than in a second plane.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: October 25, 2022
    Assignee: Gyrus ACMI, Inc.
    Inventors: Brandon J. Shuman, Hugo Xavier Gonzalez, David H. Dillard
  • Patent number: 11471325
    Abstract: An apparatus for use in tissue removal from a body organ is presented. The apparatus comprises a hand-held probe device, a rotating motor device and a connection assembly configured for removably interconnecting between the hand-held probe device and the rotating motor device. The hand-held probe device is disposable and comprises a housing having proximal and distal ends, a rotatable cutting tool extending distally from the distal end of the housing and being configured for cutting and removing tissue during rotation, and a transmission assembly passing inside the housing between the proximal and distal ends and being configured for transmitting rotational power to the rotatable cutting tool. The connection assembly is configured for engaging between the rotating motor device and the transmission assembly to thereby controllably rotate the cutting tool and remove tissue.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: October 18, 2022
    Inventors: Gilad Lavi, Yoseph Glovinsky, Vadim Shmukler, Nir Israeli
  • Patent number: 11464941
    Abstract: A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus and lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: October 11, 2022
    Assignee: Boston Scientific Limited
    Inventors: Michael J. Bonnette, Eric J. Thor, Debra M. Kozak, Douglas J. Ball, Stephen E. Weisel, David B. Morris, Richard R. Prather
  • Patent number: 11464528
    Abstract: A system for removing occlusive clot from a blood vessel comprises a catheter and an apparatus for generating a pulsatile vacuum force to pulse the pressure gradient at a distal end of the catheter. The pulse generator may be integral with or separate from the vacuum pump. The pulse generator may be applied to a flexible tubing between the vacuum pump and the proximal end of the catheter.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: October 11, 2022
    Inventors: Eamon Brady, David Vale, Michael Gilvarry, Brendan Casey, Marto Hoary, Adnan Siddiqui
  • Patent number: 11464529
    Abstract: An ultrasonic catheter assembly includes a sheath having a sheath lumen. A core wire is at least partially disposed within the sheath lumen. The core wire has a proximal portion and a distal portion. The proximal portion of the core wire is configured to be coupled to an ultrasound-producing mechanism. A working length of the distal portion of the core wire extends distally from the sheath. The working length is configured for longitudinal displacement, transverse displacement, or a combination of longitudinal and transverse displacement, in accordance with a plurality of output modes for vibrational energy supplied to the core wire proximal portion by the ultrasound-producing mechanism.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: October 11, 2022
    Assignee: C.R. BARD, INC.
    Inventors: Aseem Singh, Peng Zheng, Chad Van Liere
  • Patent number: 11458077
    Abstract: The invention relates to a composition comprising an aqueous phase and an oily phase which are visually separate and superimposed, 1,3-propanediol and a ketone compound of formula (I): wherein R1 is a C2-C4 alkyl radical; R2 is H or a C1-C4 hydrocarbon-based radical; R3 is a C1-C4 hydrocarbon-based radical; and C—X is C?O. The invention can be used for the cosmetic treatment of keratin materials.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: October 4, 2022
    Assignee: L'OREAL
    Inventors: Sofiane Ouattara, Véronique Chevalier
  • Patent number: 11452534
    Abstract: A debris removal system includes an elongated shaft extending from a proximal end to a distal end and including a shaft lumen, the shaft being configured to be inserted through a bodily lumen to a target surgical site, a vibration motor coupled to the elongated shaft via a vibration collar, the vibration motor including a rotatable shaft and at least one weight coupled to the rotatable shaft, the weight being asymmetrically shaped about a central axis of the shaft such that rotation of the shaft creates vibrational energy along the length of the elongated shaft to dislodge debris within the target surgical site, and a vacuum pump connected to the elongated shaft and configured to vacuum dislodged debris from the target surgical site through the shaft lumen.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: September 27, 2022
    Inventors: Peter J. Pereira, Martin Phelan, Vincent Lai
  • Patent number: 11446053
    Abstract: A tissue-removing catheter for removing tissue in a body lumen includes an elongate body having an axis and proximal and distal end portions spaced apart from one another along the axis. A turbine is fixed to the elongate body and is disposed at an intermediate position between the proximal and distal end portions of the elongate body. A rotatable tissue-removing element is at the distal end portion of the elongate body and is operatively coupled to the turbine such that the turbine imparts rotation of the tissue-removing element. The tissue-removing element removes the tissue from the body lumen as the tissue-removing element is rotated by the turbine.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: September 20, 2022
    Inventors: Aram Jamous, John Kelly, Colin William Meade, Micheal Moriarty, Barry O'Connell, Grainne Carroll
  • Patent number: 11439426
    Abstract: An ultrasonic surgical blade includes a body having a proximal end, a distal end, and an outer surface. The distal end is movable relative to a longitudinal axis in accordance with ultrasonic vibrations applied to the proximal end. At least a portion of the outer surface of the body comprises a lubricious coating adhered thereto. The lubricious coating has a coefficient of friction that is less than the coefficient of friction of the outer surface of the body.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: September 13, 2022
    Assignee: Cilag GmbH International
    Inventors: David A. Witt, Jeffrey D. Messerly, Kevin L. Houser
  • Patent number: 11432794
    Abstract: The invention relates to a blood flow determination apparatus (5) comprising a speckle density determination unit (7) for determining a speckle density value being indicative of a level of a speckle density in an ultrasound image of an inner lumen of a blood vessel, which has been generated at an imaging location being behind an introduction location at which a fluid has been introduced into the blood vessel (20) with a known volumetric fluid flow rate. A blood flow rate determination unit (8) determines a blood flow value being indicative of a volumetric blood flow rate based on the determined speckle density value and the volumetric fluid flow rate. This allows determining the intravascular blood flow with an improved accuracy.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: September 6, 2022
    Inventors: Christian Haase, Michael Grass
  • Patent number: 11426237
    Abstract: An electrosurgical instrument for applying to biological tissue RF electromagnetic energy and/or microwave frequency EM energy, wherein the instrument tip has a protective hull with a smoothly contoured convex undersurface facing away from a planar body, and wherein the planar body has a tapering distal edge, and wherein an underside of the planar body extends beyond the protective hull at the tapering distal edge. Also disclosed herein is an interface joint for integrating into a single cable assembly all of (i) a fluid feed, (ii) a needle movement mechanism, and (iii) an energy feed (e.g. a coaxial cable), and a torque transfer device for permitting controlled rotation of the cable assembly within the instrument channel of an endoscope. The interface joint and torque transfer device may be integrated as a single component.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: August 30, 2022
    Inventors: Julian Mark Ebbutt, Christopher Paul Hancock, Steven Morris, Malcolm White, Brian Saunders
  • Patent number: 11430289
    Abstract: A user interface assembly for a gaming device includes a first-side transceiver subassembly on a first side of a barrier, including a first-side antenna and a first-side transmitter circuit electronically coupled to the first-side antenna for transmitting an electromagnetic power signal through the barrier via the first-side antenna. The user interface assembly also includes a second-side transceiver subassembly on a second side of the barrier opposite the first-side transceiver subassembly, including a second-side antenna disposed opposite the first-side antenna relative to the barrier, and a second-side receiver circuit electronically coupled to the second-side antenna for receiving, via the second-side antenna, the electromagnetic power signal transmitted through the barrier.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: August 30, 2022
    Assignee: IGT
    Inventor: Scott Jones
  • Patent number: 11413062
    Abstract: An intravascular device is provided having a catheter tube and an expandable portion including a plurality of struts capable of being moved between an open and a closed position. An incising element is provided on at least one of the struts and has a sharpened edge for creating an incision in atherosclerotic material located within a blood vessel when the expandable portion is in the opened position. An embolic protection device may be integrated with some or all of the expandable portion.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: August 16, 2022
    Assignee: VentureMed Group, Inc.
    Inventor: John P. Pigott
  • Patent number: 11416699
    Abstract: A method and a system for generating an assistance function for an ophthalmological surgery are presented. The method includes capturing digital image data of a surgical microscope, which were generated during an ophthalmological surgery by an image sensor and which are annotated. The method furthermore includes capturing sensor data of a phaco system, which were generated during the ophthalmological surgery by a sensor of the phaco system and which are annotated, wherein the annotated sensor data and the annotated digital image data have synchronized timestamps and wherein the annotations refer in indicative fashion to a state of an ophthalmological surgery.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: August 16, 2022
    Assignee: Carl Zeiss Meditec AG
    Inventors: Stefan Saur, Christoph Hauger
  • Patent number: 11399863
    Abstract: An atherectomy catheter device includes an elongate body, a drive shaft extending proximally to distally within the elongate body, and a cutter attached to the drive shaft. The cutter includes a serrated annular cutting edge formed on a distal edge of the cutter and a recessed bowl extending radially inwards from the annular cutting edge to a center of the cutter. The recessed bowl has a first curvature. The cutter further includes a plurality of grinding segments extending inwardly from the distal edge within the bowl. Each of the plurality of segments has a second curvature that is different from the first curvature.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: August 2, 2022
    Assignee: Avinger, Inc.
    Inventors: Himanshu N. Patel, Richard R. Newhauser, Anthony J. Fernandez, Vincent Yeh
  • Patent number: 11399861
    Abstract: An instrument includes an ultrasonic blade, a first fluid port, an irrigation member, a second fluid port, and a fluid communication assembly. The ultrasonic blade defines a distal opening. The ultrasonic blade is operable in a first mode to emulsify tissue that is distally positioned relative to the ultrasonic blade. The ultrasonic blade is further operable in a second mode to transect and seal tissue that is transversely positioned relative to the ultrasonic blade. The first fluid port is in communication with the distal opening of the ultrasonic blade. The irrigation member is positioned adjacent to the distal end of the ultrasonic blade. The second fluid port is in communication with the irrigation member. The fluid communication assembly is configured to couple the first fluid port with a fluid source, couple the first fluid port with a suction source, and couple the second fluid port with the fluid source.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: August 2, 2022
    Assignee: Cilag GmbH International Zug, Switzerland
    Inventors: Foster B. Stulen, John A. Weed, III, Joseph Isosaki, Frederick L. Estera, Ryan M. Asher, Brian D. Black
  • Patent number: 11382987
    Abstract: The invention relates to methods of sonodynamic therapy comprising the co-administration of a microbubble-chemotherapeutic agent complex together with a microbubble-sonosensitiser complex. It further relates to pharmaceutical compositions comprising these complexes and their use in methods of sonodynamic therapy and/or sonodynamic diagnosis. Such methods find particular use in the treatment of cancer, e.g. pancreatic cancer.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: July 12, 2022
    Assignee: University of Ulster
    Inventors: John Callan, Anthony McHale, Eleanor Stride
  • Patent number: 11369356
    Abstract: An apparatus for inhibiting tissue migration during a procedure comprises a deployment catheter defining at least one lumen therethrough and a non-inflatable hood projecting distally from the deployment catheter and defining an open area. The open area is in fluid communication with the at least one lumen. The apparatus also comprises a visualization element disposed within or along the non-inflatable hood for visualizing tissue adjacent to the open area. The apparatus also comprises a tissue grasping end effector positioned within the open area and configured to temporarily engage the tissue adjacent to the open area such that distal migration of the tissue relative to the barrier or membrane is inhibited.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 28, 2022
    Inventors: Vahid Saadat, Ruey-Feng Peh, Christopher A. Rothe, Edmund A. Tam
  • Patent number: 11369810
    Abstract: An ultrasonic therapy system delivers ultrasonic therapy energy to a therapy site in the body which is infused with microbubbles. A system without an image guidance capability has an array transducer which delivers therapy energy, a therapy transducer driver which causes the array transducer to deliver therapeutic energy, a control for controlling the intensity of the therapeutic energy, and a display of the sonotherapy signal strength of the energy and the concentration of microbubbles at the therapy site. A system with ultrasonic imaging capability will display an ultrasound image for therapeutic guidance and a measure of the microbubble concentration. The method of the present invention is performed as an adjunct to a standard drug therapy or other treatment regimen, following such treatment with an infusion of ultrasound and delivery of ultrasound therapy energy.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: June 28, 2022
    Inventors: Michalakis Averkiou, Edward Lam Shang Leen
  • Patent number: 11364368
    Abstract: An integrated guidewire includes a wire and a flexible tube. The wire is sized and shaped to move in an anatomical material transportation system of a patient. The flexible tube is sized and shaped to move in the anatomical material transportation system, having proximal and distal ends, the proximal-end is coupled to a device external to the patient, the flexible tube is configured to transfer fluids between the distal-end and the device, and the wire and the flexible tube are intertwined with respect to one another.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: June 21, 2022
    Inventor: Assaf Govari
  • Patent number: 11364043
    Abstract: The present invention provides methods and devices for treating endovascular disease. Vibrational energy is delivered to change compliance and increase permeability at the treatment area. To improve clinical outcomes, one or more therapeutic drugs may be delivered to the treatment area.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: June 21, 2022
    Inventor: Michael P Wallace
  • Patent number: 11350963
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: June 7, 2022
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Patent number: 11344713
    Abstract: The present disclosure generally relates to methods, devices and systems relating to applying drugs or therapeutic agents to biological conduits, e.g., vascular lumens. More specifically, the present invention comprises enhancing the uptake of drugs or therapeutic agents encapsulated in microbubbles in combination with ultrasound energy as well as applying drugs or therapeutic agents in a cyclic manner using a pulse generator that may be matched in frequency with a patient's blood pulsing.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: May 31, 2022
    Assignee: Cardiovascular Systems, Inc.
    Inventors: Victor L. Schoenle, Matthew D. Cambronne, Brittany N. Pusey, Jeffrey A. McBroom
  • Patent number: 11344375
    Abstract: Surgical assemblies, instruments, and related methods are disclosed that control tissue gripping force. A method for controlling grip force in a robotic surgical instrument includes actuating an input link of a spring assembly. An actuation force is transferred from the input link to an output link of the spring assembly. Relative movement is inhibited between the input link and the output link when the transferred actuation force is below a predetermined level with a preloaded spring of the spring assembly. The input link is moved relative to the output link by deforming the preloaded spring when the transferred actuation force increases above the predetermined level. A grip mechanism is actuated via the output link.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: May 31, 2022
    Assignee: Intuitive Surgical Operations, Inc.
    Inventor: Gabriel F. Brisson
  • Patent number: 11344363
    Abstract: The present invention relates to an RF treatment apparatus including micro needles, a method of controlling the same, and a treatment method using the same according to the present invention have effects in that they can prevent damage to a tissue and perform optimized treatment because RF energy can be adjusted and applied based on a current-carrying area that belongs to a portion of the micro needles and that has been inserted into a tissue.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: May 31, 2022
    Inventors: Kwang Chon Ko, Richard Howard Cohen
  • Patent number: 11331135
    Abstract: An energy delivery probe is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply energy to tissue, such as a prostrate, to shrink, damage, denaturate the prostate. In some embodiments, the energy can be applied with a vapor media. The energy delivery probe can include a vapor delivery member configured to extend into a transition zone prostate tissue. A condensable vapor media can be delivered from the vapor delivery member into the transition zone tissue, wherein the condensable vapor media can propagate interstitially in the transition zone tissue and be confined in the transition zone tissue by boundary tissue adjacent to the transition zone tissue. Methods associated with use of the energy delivery probe are also covered.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: May 17, 2022
    Inventors: Michael Hoey, John H. Shadduck
  • Patent number: 11324878
    Abstract: An irrigation system for anal or stomal irrigation includes a tubing system attachable between a reservoir and a catheter. The tubing system has a proximal portion attachable to the reservoir and a distal portion including a distal end that is attachable to the catheter, with the tubing system providing an irrigation flow path from the proximal portion attachable to the reservoir through the distal end attachable to the catheter. A pump is operable to move the liquid through the irrigation flow path to provide the anal or stomal irrigation out of the catheter. A pressure control device is attachable to the distal portion of the tubing system and communicates with the catheter. The pressure control device has a valve that is adapted to limit an irrigation pressure for the anal or stomal irrigation out of the catheter to a value less than a pre-determined pressure threshold.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: May 10, 2022
    Assignee: Coloplast A/S
    Inventors: Niels Hvid, Henrik Bay
  • Patent number: 11324828
    Abstract: Some aspects of this disclosure relate to a method of treating an ophthalmic disease affecting an eye of a patient comprising forming a covalently-crosslinked hydrogel for controlled release of a therapeutic agent.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: May 10, 2022
    Assignee: Incept, LLC
    Inventors: Amarpreet S. Sawhney, William H. Ransone, II
  • Patent number: 11304719
    Abstract: A method for ultrasonically treating tissue includes accessing a surgical site with an ultrasonic surgical instrument, dissecting tissue with a first portion of the blade, and sealing tissue with a second portion of the blade. The instrument includes a blade that defines a longitudinal axis. The blade is configured to oscillate along the longitudinal axis to ultrasonically treat tissue.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: April 19, 2022
    Assignee: Covidien LP
    Inventors: David J. Van Tol, Anthony B. Ross, Robert B. Stoddard
  • Patent number: 11304762
    Abstract: An arrival position information estimation unit that estimates arrival position information at which an extension line of a peripheral branch included in a bronchial region arrives at a surface of a lung region, and estimates assumed mapping information other than the arrival position information of a specific peripheral branch on the basis of a preset condition in a case where the specific peripheral branch is set as a target branch, and a display control unit that generates a mapping image obtained by mapping the arrival position information of the specific peripheral branch and the assumed mapping information to a surface of the lung region and displays the mapping image on a display unit are included.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: April 19, 2022
    Assignee: FUJIFILM Corporation
    Inventor: Kenta Yamada