Abstract: Provided is a power pack comprising an AC power connector configured to be connectable to an outside AC power source; a rectification and filtering unit configured to be in electronic communication with the AC power connector; a controlling unit; and a medical device connector configured to be connectable to a medical device, the medical device connector configured to be in electronic communication with the controlling unit, wherein the power pack is configured to be capable of detecting a connection of the medical device with the power pack and also capable of demonstrating the connection through an outside indicator disposed on the exterior of the power pack once the medical device is connected to the power pack through the medical device connector.

Abstract: A device for delivering mechanical waves to treat a lesion present in a blood vessel, including a catheter extending between a first proximal end and a first distal end, an inflatable balloon secured to the catheter and being adjustable between an inflated configuration and a deflated configuration, and at least one mechanical waveguide extending between a second proximal end and a second distal end for propagating at least one mechanical wave from the second proximal end to the second distal, with the mechanical waveguide being secured to the inflatable balloon or the catheter.

Abstract: A biopsy system includes various features. A tissue sample holder kit of the system comprises a rotatable member with chambers configured to receive tissue receiving features of a tissue sample tray. A biopsy device of the system includes user input features and user feedback features disposed on a body. A user interface of the system includes a graphical representation of a tissues ample holder. A biopsy site marker applier of the system includes markings associated with different biopsy device configurations. The biopsy system may undergo a multi-step initialization process. In operation, the biopsy system may execute pneumatic control algorithms including the use of vacuum, saline, and atmospheric air.

Abstract: A method includes attaching one or more heat exchangers to one or more of a distal handle end and a proximal handle end of a lithotripter, the lithotripter including a handle, the handle having a handle distal end and a handle proximal end; a probe housed within the handle, the probe having a probe distal end and a probe proximal end; a passageway extending through the handle at least partially containing the probe; and a shielding insert contained within the passageway; wherein the probe, the passageway, and the shielding insert are contained within a central lumen of a driver resource; and performing a sterilization procedure on the surgical device; wherein the one or more heat exchangers collect and transfer heat at least through a full length of the handle, particularly to the lumen contained within the handle.

Abstract: Methods and systems for modifying tissue use a pressurized fluid stream carrying coherent light energy. The methods and systems may be used for resecting and debulking soft and hard biological tissues. The coherent light is focused within a stream of fluid to deliver energy to the tissue to be treated.

Abstract: A computing device for tracking surgical imaging devices stores a preoperative image of patient tissue registered to a frame of reference of a tracking system; and receives, from a first imaging device, a first intraoperative image of a first region of the tissue, with a finer resolution than the preoperative image. The computing device receives a position of the first imaging device from the tracking system, and registers the first intraoperative image with the frame of reference. The computing device receives, from a second imaging device, a second intraoperative image of a second region of the patient tissue, with a finer resolution than the first intraoperative image. The computing device registers the second intraoperative image to the first intraoperative image; and controls a display to present the preoperative image overlaid with the first intraoperative image, and the first intraoperative image overlaid with the second intraoperative image.

Abstract: A matrix router with frequency switching is provided having an energy source electrically connected to a plurality of interface ports. A switching device is provided between the energy source and the plurality of switches. One of the plurality of interface ports includes a paired electrode interface port for the connection of a paired electrode device thereto. The paired electrode device has a first pair of opposed electrodes and a second pair of opposed electrodes for clamping on tissue. When the paired electrode device is operably connected to the paired electrode interface port and actuated, the switching device alternates energy such as bipolar RF from the first pair of opposed electrodes to the second pair of opposed electrodes.

Abstract: A flue for use with an ultrasonic surgical tip, comprising protrusions or bumps on its inner surface with improved protrusion pattern, density and location. The flue has enhanced cooling effect for the ultrasonic surgical tip.

Abstract: Medical systems and methods for making and using medical systems are disclosed. Example medical systems may include an atherectomy system configured to engage and remove plaque from walls in vessels of a vascular system. The atherectomy system may include a drive shaft, a rotational tip coupled to an end of the drive shaft, a drive mechanism coupled to the drive shaft to rotate the rotational tip, and a control unit configured to control operation of the drive mechanism. In some cases, the control unit may include a controller for controlling operation of the drive mechanism based on sensed positions of the drive mechanism. The controller may be configured to send data to a host for analysis, compensate a control signal based on a mode of operation of the drive mechanism, determine if a stall is predicted to occur, and/or perform one or more other functions.

Abstract: Cantilever probes are produced for use in a test apparatus of integrated electronic circuits. The probes are configured to contact corresponding terminals of the electronic circuits to be tested during a test operation. The probe bodies are formed of electrically conductive materials. On a lower portion of each probe body that, in use, is directed to the respective terminal to be contacted, an electrically conductive contact region is formed having a first hardness value equal to or greater than 300 HV; each contact region and the respective probe body form the corresponding probe.

Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.

Abstract: An intratumoral modulation therapy (IMT) method for the treatment of nervous system and systemic tumor in a patient which includes: (a) chronically implanting an electrode adjacent to or in the tumor of the patient or in a residual tumor bed, the electrode having electrical leads connected thereto; and (b) generating electric stimulation and applying the electric stimulation through the electrical leads to the electrode adjacent to or within the tumor. A method of transferring genetic material to a tumor cell which includes: (a) positioning an electrode adjacent to the tumor cell, the electrode having electrical leads connected thereto; (b) generating electric stimulation and applying the electric stimulation through the electrical leads to the electrode adjacent the cancer cell; and (c) delivering the genetic material to the tumor cell treated with the continuous alternating electric stimulation.

Abstract: An endoscopic stone-extraction device is provided comprising a support filament comprising an end portion having a plurality of stacked loops, a sheath comprising a lumen, wherein the support filament is disposed in the lumen such that the sheath is slideable with respect to the support filament, and a handle comprising an actuator. Movement of the actuator in a first direction retracts the sheath and causes the plurality of stacked loops to expand outside the lumen in an arc-like shape. Movement of the actuator in a second direction advances the sheath and causes the plurality of stacked loops to at least partially collapse inside the lumen. Other embodiments are provides, and any of these embodiments can be used alone or in combination.

Abstract: The present invention is about composition for preventing hair loss or promoting hair growth comprising indirubin derivatives; and one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin; as an active ingredient. In addition, one or more selected from the group consisting of Euodia daniellii extract, Persicaria hydropiper extract, Hovenia dulcis extract, methyl vanillate, hesperidin and quercitrin of the present invention is a natural-derived composition with little toxicity to cells. Indirubin derivatives are stable compounds that have been found to have little toxicity to the human body, and therefore, when used in a mixture thereof, there are advantages in that they do not exhibit adverse effects on the human body, unlike conventional steroid drugs.

Abstract: An ultrasonic surgical instrument includes a waveguide defining a blade at a distal end thereof and a lumen extending through a portion of the blade. The blade is configured to receive ultrasonic energy for treating tissue. The instrument further includes first and second conduits each defining a proximal end and a distal end. The second conduit is coaxially disposed about the first conduit. The distal ends of the first and second conduits extend into the lumen. The distal end of the first conduit extends further distally into the lumen than the distal end of the second conduit.

Abstract: Rotational atherectomy devices and systems can remove or reduce stenotic lesions in implanted grafts by rotating one or more abrasive elements within the graft. The abrasive elements can be attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, individual abrasive elements are attached to the drive shaft at differing radial angles in comparison to each other (e.g., configured in a helical array). The centers of mass of the abrasive elements can define a path that fully or partially spirals around the drive shaft.

Abstract: The present invention provides a system and a method for managing occlusions and reducing eye tissue damage during phacoemulsification surgery. More specifically, the present invention provides automated control of the application of ultrasonic energy to a partial or full occlusion of a surgical tool. The present invention measures the vacuum pressure and automatically adjusts the application of ultrasonic energy when the vacuum pressure indicates an occlusion or an occlusion break.

Abstract: An energy treatment instrument includes a first grasping piece, and a second grasping piece which opens or closes relative to the first grasping piece and which grasps a blood vessel between the first grasping piece and the second grasping piece. In accordance with the kind of blood vessel grasped between the first grasping piece and the second grasping piece, an actuation state of the energy treatment instrument is switched between a first mode to coagulate a blood vessel of a circulatory system, and a second mode to coagulate a blood vessel of a pulmonary circulation in contrast to the first mode.

Abstract: A powered surgical instrument comprising an end effector, a sensor configured to output a signal, an elongate shaft, and a handle is disclosed. The end effector comprises a first jaw, a second jaw movable relative to the first jaw, a channel, a staple cartridge, an anvil, and a firing member configured to be driven during a firing stroke. The firing member experiences a pushing force during the firing stroke and comprises a knife portion, a first camming member configured to engage the first jaw, a second camming member configured to engage and position the second jaw. The handle comprises a motor, a battery, means for detecting the pushing force of the firing member, and a control unit configured to receive the signal from the sensor. The control unit includes a microprocessor which utilizes a pulse width modulation circuit to control the motor based on the signal received from the sensor.

Abstract: A compound transmission member including: a first tube sub-member and a second tube sub-member, each including: a first end having a first opening and a second end having a second opening, wherein the first opening is in fluid communication with the second opening, and wherein at least the first tube sub-member is configured to transmit ultrasonic energy; and a fitting configured to receive the first ends of the tube sub-members.

Abstract: An ultrasound probe includes a probe body, and a treatment unit. The treatment unit includes: a cutter that is provided at a distal end part of the treatment unit and that cuts the bone according to move of the treatment unit along a longitudinal axis in a state where ultrasonic vibration is being transmitted to the probe body; and a path that is provided in the treatment unit and through which debris of a bone that is cut by the cutter are discharged along the longitudinal axis toward a proximal end side with respect to the cutter. The path includes a first opening that is provided in a distal end surface of the cutter; and a second opening that is provided in a side surface part of the treatment unit, wherein the path allows the first opening and the second opening to communicate.

Abstract: A microneedle using a biodegradable metal is represented by Chemical Formula 1 and is absorbed and degraded after subcutaneous or epithelial insertion to thus release metal ions and degradation products into the body. In Chemical Formula 1, a, b, and c represent wt % of respective ingredients, a+b+c=100 wt %, a or b has the highest value in the range of 0?a?100, 0?b?100, and 0?c?10, and X is one or more selected from the group consisting of Ca, Fe, Mn, Si, Na, Zr, Ce, and P.

Abstract: An end effector for use with a surgical system is disclosed. The end effector comprises a medical adjunct gradually releasable from the end effector, a pair of jaws configured to grasp tissue therebetween, a firing member, and a cutting member configured to cut the tissue and gradually release the medical adjunct from the end effector in an overlapping timeframe, based on advancement of the firing member.

Abstract: An end effector assembly of a tissue resecting device includes a cutting member and an elongated outer shaft. The cutting member includes a core defining a passage and a plurality of blades extending radially outward from the core. Adjacent blades define a gap therebetween. The plurality of blades defines at least one window in communication with the passage of the core. The elongated outer shaft includes a tool portion rotatably receiving the plurality of blades of the cutting member therein. The tool portion defines a lateral opening such that the plurality of blades of the cutting member rotatably received in the tool portion is in registration with the lateral opening. The cutting member is transitionable between a neutral position, in which, the cutting member defines a longitudinal axis, and an articulated position, in which, at least a portion of the cutting member is offset from the longitudinal axis.

Abstract: A plurality of control-signal generators are configured to generate respective control signals having respective control-signal amplitudes and different respective control-signal frequencies, and a plurality of signal adders are configured to produce respective composite signals for application to a subject, by adding the control signals to respective ablation signals having respective ablation-signal amplitudes. The control-signal generators are configured to generate the control signals such that respective ratios between the control-signal amplitudes and the ablation-signal amplitudes are constant during the application of the composite signals to the subject.

Abstract: A method of treating a soft palate in a patient to treat sleep apnea, snoring or both may involve advancing a treatment element of a treatment device through the patient's mouth, contacting a tissue-contact surface of the treatment element with the soft palate, delivering energy to the soft palate via one or more energy delivery members on the tissue-contact surface, and removing the treatment element from the mouth.

Abstract: An intravascular cutting device described herein uses high-pressure water, saline, or other fluid to cut tissue and other materials including but not limited to calcified tissue, stents, stent grafts, and other devices. In some embodiments, the cutting device includes a working end that has a nozzle with a hole to allow the release of a high-pressure fluid jet. Opposite of the nozzle is a catch plate or deflector anvil that prevents the fluid jet from cutting healthy tissue. The device user will place the item to be cut between the nozzle and catch plate and then advance the device along the item to be cut as the fluid jet is activated, thus cutting the object as it advances.

Abstract: A surgical apparatus comprises a body, an ultrasonic transducer, a shaft, and an end effector. The ultrasonic transducer is operable to convert electrical power into ultrasonic vibrations. The body comprises a pivotal trigger. The shaft couples the end effector and the body together. The end effector comprises a clamp arm and an ultrasonic blade in acoustic communication with the ultrasonic transducer. The ultrasonic blade is operable to deliver ultrasonic vibrations to tissue. Pivotal movement of the trigger causes movement of the clamp arm. The trigger includes a compliant feature configured to limit the amount of force delivered to tissue by the clamp arm. The flexible feature may comprise a flexible band, living hinge, a series of living hinges, or a flexible tab.

Abstract: An powered hair restoration and surgical assembly includes a housing for gripping during a surgical procedure. A blunt dissector is removably coupled to the housing for manipulating an incision. A control circuit is positioned in the housing and an incising unit is movably positioned in the housing. The incising unit is electrically coupled to the control circuit. The incising unit is extendable outwardly through the blunt dissector to incise skin on a patient and the incising unit is retractable into the blunt dissector. A fluid dispenser unit is positioned in the housing and the fluid dispenser unit is electrically coupled to the control circuit. The fluid dispenser unit is in fluid communication with the incising unit to deliver a selectable volume of the fluid into the incision when the incising unit is extended outwardly through the blunt dissector. A control is positioned on the housing.

Abstract: The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002? to about 0.008?.

Abstract: An endoluminal punch system including a sheath and dilator. The endoluminal punch may include energy delivery system capable of being transmitted from the proximal end to the distal end of the endoluminal punch to assist with tissue crossing and incisions. The dilator may include selectively deployable cutting mechanism to create incisions in tissue that are larger than their basic external diameter. The system may also be configured to reduce the risk of generating plastic emboli during insertion of the endoluminal punch.

Abstract: A treatment method and medical device are disclosed for cutting a substance inside a body lumen. The medical device includes a drive shaft that is rotatable; a strut that is rotatably connected to a distal side of the drive shaft, that extends along a rotation axis, and whose central portion is expandable radially outward; and a support portion that is rotatably connected to the distal side of the drive shaft, that is formed in a mesh shape and a tubular shape while including multiple gaps, at least a portion of which is positioned on a radially inner side of the strut, and that is expandable radially outward by a central portion in a direction extending along the rotation axis being bent.

Abstract: An implantable actuation device that may be used with a glaucoma drainage device or attached to an ocular surface, a method of making an implantable actuation device, and a method of preventing cell adhesion resulting from a glaucoma treatment procedure. The implantable actuation device is made from a magnetoelastic material. Actuation of the magnetoelastic material may help control cellular adhesion that may develop and undesirably disrupt proper healing when recovering from invasive surgical treatments. The implantable actuation devices may have small form factors and customized geometries which include three-dimensional curvatures to help promote the actuation of liquid flow and facilitate the removal of unwanted cells.

Abstract: In some examples, a medical device includes a flexible elongate member configured for navigation through vasculature of a patient to a target treatment site. A distal portion of the elongate member including a first balloon portion that is inflatable to an expanded state, a second balloon portion that is inflatable to an expanded state, and a cavitation generator. When the balloon portions are in their expanded states within the vasculature, a cavity is defined between the elongate member and the target treatment site and exterior to the first and second balloon portions. The cavitation generator is configured to deliver energy to a fluid within the cavity to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.

Abstract: A method of treating abnormal tissue within a patient includes positioning a delivery cannula within the patient, the delivery cannula having a first electrode disposed on its distal end; introducing an ablation probe through the cannula and out an open distal end thereof, so that a second ablation electrode carried on the ablation probe contacts abnormal tissue within the patient; conveying ablation energy between the first and second ablation electrodes to ablate the abnormal tissue; and introducing a separate medical element, whether a device or a therapeutic agent, through the cannula before or after the ablation process.

Abstract: A medical device includes an elongated sleeve having a longitudinal axis, a proximal end and a distal end. A ceramic cutting member includes both a cutting window having sharp edges and one or more flutes with cutting burrs circumferentially spaced-apart from the cutting window. An electrode may be placed between a pair of flutes and opposite to the cutting window. A motor drive is coupled to the proximal end of the elongated sleeve to rotate the ceramic cutting member cut bone with the flute(s) and soft tissue with the cutting window. The electrode provides cautery or radiofrequency ablation of tissue when the sleeve and ceramic cutting member are not being rotated.

Abstract: A system and method for provided a phacoemulsification surgery handpiece including a convertible sleeve for phacoemulsification surgery and irrigation/aspiration procedures. In a retracted state, the sleeve is in a desired relationship with the exposed portion of a phaco tip of the handpiece to support normal phacoemulsification surgery. In an extended state, the sleeve features a distally placed aspiration hole located forward from the distal end of a phaco tip to allow typical irrigation/aspiration procedures. A distal tip segment of the hand piece is overmolded by polyimide materials having a split feature to allow egress of a phaco tip.

Abstract: A surgical device incorporating a powered rotary cutting tool having a protective distal foot plate which protects against injuring non-target tissue enabling the rapid and safe removal of specifically-targeted bone, cartilage, and soft tissue.

Abstract: Embodiments of the invention provide an energy conveying structure for delivering RF and/or microwave energy to an electrosurgical instrument, where the energy conveying structure is incorporated into an insertion tube of a surgical scoping device (e.g. endoscope, laparoscope or the like). The insertion tube is a flexible conduit that is introduced into a patient's body during an invasive procedure, and can include an instrument channel and an optical channel. The energy conveying structure may be a layered coaxial structure that formed a liner that fits within the scoping device, e.g. within an instrument channel. Alternatively, the energy conveying structure may be a coaxial structure integrally formed as part of the flexible conduit.

Abstract: The present invention provides methods and devices for treating endovascular disease. Vibrational energy is delivered to change compliance and increase permeability at the treatment area. To improve clinical outcomes, one or more therapeutic drugs may be delivered to the treatment area.

Abstract: The present disclosure is directed to a tissue removal device. The tissue removal device may include a distal portion. The distal portion may include an outer distal portion including a tissue removal tool, and an inner distal portion positioned within the outer distal portion and having a closed distal end, a lumen, and at least one side port, wherein the lumen is configured to receive a medical device, and the inner distal portion is movable relative to the outer distal portion and the medical device.

Abstract: A vitrectomy instrument and a system including the same are disclosed herein. The vitrectomy instrument includes a handpiece having an outer tube and an inner tube coaxially disposed in the outer tube, the inner tube being slidably displaceable relative to the outer tube; a cutting power generator operatively coupled to the inner tube, the cutting power generator configured to reciprocably drive the inner tube for shearing tissue and/or vitreous; and an ultrasonic generator operatively coupled to the inner tube, the ultrasonic generator configured to vibrate the inner tube for vibratory fragmentation and/or cutting of the tissue and/or the vitreous. The vitrectomy system may include the vitrectomy instrument together with a support sleeve for supporting the vitrectomy instrument to provide increased rigidity to the needle of the vitrectomy instrument.

Abstract: A surgical instrument includes an ultrasonic transducer, an ultrasonic transmission waveguide extending from the ultrasonic transducer, and an ultrasonic blade acoustically coupled to the ultrasonic transmission waveguide. The ultrasonic blade includes a base and a curved body extending distally from the base. The curved body includes a tissue-treating surface extending on a first side of the curved body and a curved edge extending on a second side of the curved body opposite the first side. The curved edge has a proximal end and a distal end, wherein the proximal end is offset from the distal end in a first direction, wherein the proximal end is offset from the distal end in a second direction, and wherein the first direction is perpendicular to the second direction.

Abstract: A surgical tool that has a pair of transmissions coupled to one another to effect driving of a cutting tool in both an oscillating manner and a reciprocating manner. The transmissions are driven by a motor coupled to one of the transmissions.

Abstract: A device for transmitting mechanical waves, including a mechanical waveguide having an elongated shape and extending between a proximal end and a distal end for propagating the mechanical waves coupled at the proximal end up to the distal end, and a radiopaque marker secured to the mechanical waveguide adjacent to the distal end thereof.

Abstract: Methods and systems for automatically pulsing different aspiration levels to an ocular probe are disclosed. The probe may be a phacoemulsification probe. A first aspiration level, supplied by a first pump, may be applied to the probe simultaneously with ultrasonic energy. A second aspiration level, supplied by a second pump, may be automatically switched from the first aspiration level, and applied to the probe in a pulsed manner.

Abstract: According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

Abstract: In various embodiments, a drainage device includes an inner lumen configured for draining fluid from a target site and one or more outer lumens for transmitting dilution fluid to the inner lumen. According to one embodiment, the drainage device includes one or more eyelets and/or a distal opening through which the fluid from the target site enters the inner lumen. In one or more embodiments, the dilution fluid is transmitted to the inner lumen through one or more ports that may output the dilution fluid directly into the inner lumen or into the eyelet. According to one embodiment, as the fluid from the target site flows through the drainage device, the dilution fluid reduces clotting processes such that formation of blockages within the inner lumen is prevented or at least reduced. In some embodiments, the dilution fluid is substituted with, or provided in addition to, pharmaceutical solutions or other infusions.

Abstract: A system and method for cutting tissue within a synovial cavity, which includes a cannula and a blade assembly. The cannula can define an internal lumen and a cutting port for accessing the internal lumen. The blade assembly can include a blade and a blade shall extending from the blade. The blade can be inserted into the internal lumen of the cannula through an access port of the cannula such that the blade is proximate the cutting port. The blade shaft can be operated to move the blade within the internal lumen relative to the cutting port between a retracted position and a deployed position. The blade can be received within the internal lumen in the retracted position and positioned, at least partially, within the cutting port in the deployed position.

Abstract: An ultrasonic probe includes a treatment portion that has a through-hole or concave portions. The through-hole extends from a first outer surface to a second outer surface facing in an opposite direction to that of the first outer surface. The concave portions include a first concave portion on the first outer surface, and a second concave portion on the second outer surface. The treatment portion includes a blade formed along an edge of an opening of the through-hole or the first concave portion. An outer relay surface extends from the blade to the second outer surface and faces away from a center axis of the through-hole or the concave portions. A distance from the center axis to the blade is greater than or equal to a distance from the center axis to the outer relay surface at a position between the blade and the second outer surface.