Abstract: The present invention generally provides improved medical devices, systems, and methods. Embodiments may be particularly well suited for the treatment of dermatological and/or cosmetic defects, and alternative embodiments may be configured for treatment of a wide range of target tissues. Some embodiments of the present invention apply cooling with at least one small, tissue-penetrating probe, the probe often comprising a needle having a size suitable for inserting through an exposed surface of the skin of a patient without leaving a visible scar. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments make use of replaceable needle probes supported by a probe body handle, with small needle probes often being replaced during treatment of a single patient. Unlike the large format cryogenic cooling systems of the past, small cryogenic cooling needle probes may dull or be damaged by insertion.

Abstract: A system for treating a tissue site of a patient includes a dressing filler adapted to be positioned at the tissue site. The dressing filler includes a base and a plurality of nodes extending from the base. The base further includes a plurality of openings disposed in the base. At least one of the plurality of nodes is comprised of a non-tactile-stimulus-activated, macroscopically-deforming (NTSAMD) material.

Abstract: A system and method of topically applying an anesthetic, or other medication, to one or both lips of the mouth. An applicator device is provided that has a curved first wall, a curved second wall, and a horizontal shelf that joins the first wall to the second wall. The first wall, the second wall and the horizontal shelf combine to define either one or two curved lip compartments. A volume of the anesthetic, or other medication, is placed within the curved lip compartments. The applicator device is partially placed in a person's mouth so that the second wall is positioned between the back of the lips and in front of the teeth. While in this position, the lip of the user passes into the curved lip compartment and is contacted by the anesthetic.

Abstract: A portable heater with ovoid receptacle is disclosed. The portable heater comprises a top member comprising a semi-ovoid cavity, a bottom member comprising a semi-ovoid cavity, a hinge operatively connected to the top and bottom members, and a heating mechanism.

Abstract: Embodiments disclosed herein propose the controlled application of a heated spray cloud to a target surface. The spray cloud may be delivered in connection with applications of atomized (misted) sunless tanning sprays using a variety of spray systems. A formulation of the cosmetic or conditioning liquid may conduct and retain heat to allow a pleasantly warm spray to be received on the skin surface. The formula may come to temperature quickly and the heat may be retained even though a nozzle cooling effect inherently cools the spray as it leaves the nozzle.

Abstract: Applicators provide heat shields for uncovered skin, in particular the face, hands, and other body parts that may not be clothed such as arms, legs, or torso. In one embodiment, a continuous heat shield is applied the entire face and ears. In another embodiment, a heat shield is applied to portions of the face and neck. In yet another embodiment, a heat shield is applied by multiple applicators. Sets of applicators apply a portion of a contiguous heat shield. Books contain multiple sets of applicators. Camouflage is used for military concealment. Other uses include firefighting, iron working, glass blowing and cooking. Entrained ceramic particles provide heat reflection and insulation.

Abstract: Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances (for example, stimulants) in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible.

Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.

Abstract: A series of implementations of open access sleeves for holding one or more closed containers of sterile fluid for use in medical procedures are disclosed. The open access sleeves may be adapted to provide heat to maintain the containers of sterile fluid above the ambient air temperature of the room. The provision of heat may be controlled by a control system. The control system may use a temperature measurement device to obtain a temperature representative of the container of sterile fluid and of the sterile fluid in the container. The access sleeve may be included in a device for maintaining an open volume of sterile fluid within a range of a target temperature to maintain the closed containers of sterile fluid at a temperature near target temperature for open volume of sterile fluid.

Abstract: A therapeutic device includes an elastomeric outer shell configured as a human hand and defining an interior area, the outer shell having a finger end opposite a wrist end. The device includes a pocket in the interior area, the pocket being defined by an inner wall. An endplate is coupled to the outer shell and coupled to the inner wall to define a closed area between the outer shell and pocket, the endplate having an opening for allowing access to the pocket. A fill material is positioned in the closed area. The device includes a vibrating unit removably positioned in the pocket through the endplate opening, the vibrating unit having a lock complementary to a catch to couple the vibrating unit to the endplate, the vibrating unit having a vibrating motor in electrical communication with a power source and a switch.

Abstract: A method for treating wounds, comprised of the application of reduced pressure to a wound site and alteration of the temperature over said wound. A system for wound healing, comprising: a substantial impermeable drape sized to cover and enclose the wound creating a reservoir and adapted to maintain reduced pressure at the site of the wound; a sterilizable porous cooling pad incorporated into a wound sponge adapted to provide localized cooling to said wound, said cooling pad located between said wound and said cover or over the drape; a reduced pressure supply mechanism capable of providing subatmosphere pressure over said wound site.

Abstract: A device for applying an ophthalmologic medicament to a patient's eye is disclosed. The device comprises spectacles defined by a frame and at least one lens; at least one container adapted for accommodating the ophthalmologic medicament; the container is incorporated into the frame; dosing mechanism adapted to control doses of the medicament; and at least one nozzle in a fluid interconnection with the medicament container; the nozzle is secured mechanically to the frame; the nozzle is adapted for providing a medicament mist flow. The nozzle is placed in front of a peripheral portion of a patient's eye slot and adapted to provide the mist flow in front of the patient's eye.

Abstract: The present invention provides a device to facilitate the self-administration of eye drops. The device includes a body portion adapted for placement on the user's face, generally over the eye in which the drops are to be applied. The body portion preferably includes an integral handle which may be held between the thumb and forefinger of the user. Many embodiments may also incorporate a nose bridge to assist in locating the device in the correct position.

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract: Disposable injection devices are disclosed herein. In an exemplary arrangement, the disposable injection device comprises an annular sleeve, a predetermined pre-injection quantity of a substance configured for selective injection, and a temperature control element. The annular sleeve at least partially defines a dispensing chamber therein. The predetermined pre-injection quantity of the substance configured for selective injection is disposed within the dispensing chamber. The temperature control element is operably connected to the dispensing chamber, and is configured to selectively heat the substance to a predetermined temperature. The substance expands from the pre-injection quantity at the predetermined temperature to an injection quantity whereby the injection quantity is greater than a volume defined by the dispensing chamber. In this manner, a predetermined minimum quantity of the substance is self-expelled from the dispensing chamber.

Abstract: A method and apparatus for thawing and delivery of cryogenically frozen biological material, such as stem cells includes a housing for receiving a pouch of frozen cells, a heating element against which the pouch is placed for applying defrosting heat to the pouch, and a squeezing apparatus for applying a squeezing force to the pouch after or upon thawing of the cells. The squeezing force may be applied by a roller pressing the pouch against the heating element, which forces the thawed cells from a needle or tube connected to the housing and/or to the pouch. A rechargeable battery in the housing supplies power to the heating element and the squeezing apparatus.

Abstract: A liquid warming device for heating sterile fluids in a removable basin is described with emphasis on the properties of the basin interaction with the liquid warming device and with a drape that works with the basin to maintain a sterile field above the drape and the top of the basin. Also disclosed are various desirable aspects for a control system for a liquid warming device.

Abstract: The present invention is an ophthalmic injection system with a limited reuse assembly and a tip segment. The tip segment is connectable to and removable from the limited reuse assembly. The tip segment includes a dispensing chamber, a plunger, and a housing. The dispensing chamber holds a quantity of a substance to be injected into an eye. The proximate end of the plunger has a first mechanical linkage interface. The limited reuse assembly of the ophthalmic injection system has a power source, a controller, a motor, a second mechanical linkage interface located on an end of the motor shaft; and a second housing. The first mechanical linkage interface is mateable with the second mechanical linkage interface such that when the tip segment is connected to the limited reuse assembly, the first mechanical linkage interface mates with the second mechanical linkage interface so that motion of the shaft results in motion of the plunger.

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract: The device is provided to reduce trauma caused by childbirth or other traumas and absorb such fluids which would be expelled after such a trauma. In particular the device is said to reduce the trauma of the wound in the perineal region or other regions, and absorb blood and other discharges after such a trauma. The device is comprised of a cotton maternity sanitary napkin which is an absorbent housing for the instant cooling ice pack which is cooled prior to application to the perineal region. To activate the ice pack one must squeeze it and wait to hear a pop sound which allows the chemical to mix creating the cooling sensation. The said device contains an adhesive strip which can be activated by pulling off the plastic tape cover. The adhesive strip then can be placed in the woman's underwear to ensure a secure placement of the device.

Abstract: A system and method for portably delivering a therapeutic dose of heat to the skin to relieve pain, reduce accommodation of thermal nerve receptors, promote healing, and deliver transcutaneous medications. The heating device is user programmable or pre-programmed to deliver according to a variety of cycles, patterns and algorithms. The cycles, patterns, and algorithms of the heat are programmable parameters, are under the user's control, and increase the effectiveness and efficiency of the device. The heating algorithms are designed to interact with an individual user's thermal nerve receptors and other tissue characteristics and to reduce the tendency of the receptors to accommodate to the external stimuli with back pain, muscular pain, dysmenorrhea, headaches, fibromyalgia, post-herpetic neuralgia, nerve injuries and neuropathies, and sprains and strain.

Abstract: A novel moist steam heating cabinet unit is used as a medical device for humidification, hydration and dispensing of medicinal Hot Packs. The technology provides multifunctional options for both medicinal and non medicinal hot pack treatment as well as for other applications and uses, for example—including creation, manufacturing and curing of pharmaceutical compounds that require a controlled steam process and method. A moist heating device is a unit designed and constructed to deliver a timed, heated fluidic steam coming from a moisture generating heating source. This moist heating by employing steam heat activates the therapeutic potential of a portable topical compress or hot pack wrap applicator, of various shapes and sizes, for transdermal use and neat applications of a “wet medicinal dressing.” The moisture provides the activating liquid and fluidic environment for the flowing through, titrating, and permeating delivery of drugs or medicaments held within a medicinal pack.

Abstract: The present invention relates to an active transdermal drug delivery system performing transdermal drug delivery comprising of a patch capable of being attachable to the skin of the subject; at least one electrical energy power input; a plurality of converters/energy transducers configured for converting the electrical energy to different forms of energy; and a controller including a programmable microprocessor configured for providing the intensity, sequence, nature, and timing information for the different energies supplied and thereby providing activating signals to the said converters for the transdermal drug delivery by the said patch, and a method for performing transdermal drug delivery using said electronic patch.

Abstract: An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed.

Abstract: A hand held spray system for skin treatments includes air outlets for delivering heated air to improve the efficacy and comfort of the spraying experience. The heated air may also heat a liquid tip and transfer this heat to the skin treatment. The heated air may be applied while spray is emitted from the nozzle to increase the spray cloud temperature, or may be applied before or after the spray application, with the spray turned off, to warm or dry the skin. The spray system includes a heating source to warm the air as it passes through the system and is delivered through atomizing and/or pattern shaping orifices.

Abstract: The prevention invention relates to a moxa holder support and a moxibustion device comprising the same, and more particularly, to a moxa holder support which provides comfort to a patient receiving moxibustion, and to a moxibustion device in which the temperature of part of a human body, to which moxibustion is applied, can be easily controlled according to the characteristics of the related organ of the human body. When receiving moxibustion using the moxa holder support according to the present invention, a patient can feel comfortable because part of the patient's skin to which moxibustion is applied comes into contact with the leather connected to the bottom of a main body of the moxa holder support and the texture of pig skin, cow skin or sheep skin used as the leather in the present invention is similar to that of human skin.

Abstract: A heat generating device includes a holder and a heat generating member that is enclosed in the holder and that contains an oxidizable metal, a reaction accelerator, an electrolyte, and water. The heat generating member contains a transdermally-absorbable medicament and a solvent for dissolving the transdermally-absorbable medicament. It is preferable that the solvent is at least one type of polyol selected from polyols that are in their liquid state at 25° C. It is also preferable that the heat generating member further contains at least one type of solvent composed of an oily agent that is in its liquid state at 25° C. It is also preferable that the heat generating member further contains a surfactant. It is also preferable that the polyol is polyethylene glycol.

Abstract: A system for heating a medical fluid includes a container including a fluid path including an inlet side and an outlet side. A broadband infrared radiation source including a power supply is coupled to a broadband emitter for emitting infrared radiation. The broadband emitter provides a focal location within the fluid path to heat the medical fluid to generate a heated medical fluid. A flow turbulence enhancing structure mixes the heated medical fluid to reduce temperature gradients therein. A fluid detector senses a presence of the medical fluid in the fluid path and generates a fluid sensing signal. A controller is coupled to receive the fluid sensing signal and has an output coupled to the power supply for controlling a power output of the power supply based on the fluid sensing signal indicating a presence of the medical fluid in the container.

Abstract: An infusion fluid heating apparatus applicable to various types of infusion tube with different length dimensions includes a front-side tube fitting groove or a rear-side tube fitting groove formed on one of surfaces of a heating plate that receives an infusion tube in a first length between an inlet opening and an outlet opening open at the end surfaces of the heating plate. The groove also receives the infusion tube in a second length shorter than the first length. Therefore, the groove uses the second length for a relatively short infusion tube, capable of heating the tube appropriately and achieving high versatility. In addition, the tube fitting groove uses the first length for an infusion bag with a relatively long infusion tube, capable of heating the tube appropriately and increasing the maximum infusion fluid flow.

Abstract: This disclosure relates generally to methods for increasing the permeability of tissue. More particularly, it relates to increasing the permeability of a skin tissue or other epidermal tissue to promote delivery of active substances locally and systemically, and to control the delivery of active substances topically.

Abstract: According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C.

Abstract: A spray nozzle system for skin treatments includes separate air outlets moving over the skin surface to deliver one or more streams of supplemental air for the purpose of warming or drying the skin surface to improve efficacy and comfort of the spraying experience. The drying air from the auxiliary ports may be applied while spray is emitted from the nozzle to increase the spray cloud temperature, or may be applied before or after the spray application, with the spray turned off, to warm or dry the skin. A heating source is provided to warm the air directed through one or more supplemental air ports. In the case of air-atomizing nozzles, the supplemental air is delivered through low pressure ports separately from the air emitted through the nozzle's atomizing and pattern shaping orifices to minimize the expansion cooling effect inherent with the spray nozzle ports.

Abstract: There are provided thermal treatment system that utilizes a rotating coupling between a heating or chilling unit that provides a heat transfer fluid and a heat exchange bladder used to provide therapy to a mammal. The use of the rotating coupling permits the mammal to move about in a stall, assume a sleeping position or exercise while still receiving therapy.

Abstract: A portable heater with ovoid receptacle is disclosed. The portable heater comprises a top member comprising a semi-ovoid cavity, a bottom member comprising a semi-ovoid cavity, a hinge operatively connected to the top and bottom members, and a heating mechanism.

Abstract: Compositions and method for augmenting tissue after delivery to localized area. The compositions include a hydrogel and a dermal filler. The hydrogel can polymerize and/or crosslink upon a first trigger event. The dermal filler can also optionally crosslink upon a second trigger event.

Abstract: An absorbent article includes a backsheet having a longitudinal axis, a topsheet attached to the backsheet and having a body-facing surface, and an absorbent core disposed between the backsheet and the topsheet. The article may also include barrier leg cuffs. The article further includes a sensation aspect, which sensation aspect may be provided between the core and the topsheet. The sensation aspect may be, for example, a temperature sensation aspect. A visible indicator may be associated with the sensation aspect.

Abstract: Embodiments of the present invention relate to a cosmetic treatment method that treats the human scalp, including applying a cosmetic composition and/or a gas to the scalp with a spray device operating with a compressed gas, a mean size of the sprayed particles of composition lying in the range 10 ?m to 35 ?m.

Abstract: This invention is directed to a therapeutic patch for ophthalmologic and cosmetic use that provides therapy to the region where the patch is provided; the therapeutic patch provides a therapeutic delivery surface for placement against, for example, the eyelid and peri-orbital structures of a patient, and a non-contacting surface that can be used, for example, to generate heat and/or moisture for transmission to the surface to which therapy is being applied. The invention also includes a kit for at-home care of a region requiring therapy, in a manner that inhibits transmission of infectious agents.

Abstract: An ophthalmic injection system has a tip segment attachable to and removable from a limited reuse assembly. The tip segment has a dispensing chamber housing, a plunger, a needle, a temperature control device, a thermal sensor, and a first housing at least partially enclosing the dispensing chamber housing, the temperature control device and the plunger. The limited reuse assembly has an actuator with a shaft, a power source for providing power to the actuator, a controller for controlling the actuator, a mechanical linkage interface, and a second housing at least partially enclosing the power source, the controller, and the actuator. The mechanical linkage interface is coupled to the actuator shaft and has a mating surface on one end. The substance is injected after the temperature of the substance is altered.

Abstract: Cooling products and methods of manufacture are disclosed. The cooling product is comprised of a substrate impregnated with a polymer gel and an antimicrobial agent. The product may be a compression wrap, pad, body wrap, container wrap, blanket or article of clothing.

Abstract: A device for treating human keratinous materials includes an electrical appliance comprising a handpiece and a reader, and an applicator suitable for being removably fastened on the handpiece. The applicator includes a solid cosmetic or dermatological composition for applying to the keratinous materials, and/or an applicator element including fibers and/or cells suitable for enabling a cosmetic or dermatological composition to be applied on keratinous materials. The applicator also includes an encoder for encoding information arranged to be read by the reader. The operation of the handpiece depends on the information read.

Abstract: An infected nail of a digit of a patient is treated using apparatus including an enclosure capable of housing at least a distal end of at least one digit of a patient having an infected nail. The apparatus also includes a heater and a nail infection agent-containing member housed within the enclosure and positionable against an infected nail at the distal end of a digit housed within the enclosure. The heater is in heat-transfer relationship with the nail infection agent. In this way heated nail infection agent can be maintained against an infected nail by the nail infection agent-containing member.

Abstract: A disposable injection device has a dispensing chamber housing, a plunger, a needle, and a temperature control device. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The plunger has a plunger interface. The needle is fluidly coupled to the dispensing chamber. The temperature control device at least partially surrounds the dispensing chamber housing and alters a temperature of the substance in the dispensing chamber. The substance is injected after the temperature of the substance is altered.

Abstract: An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.

Abstract: The invention relates to a hair removal device (1) having a hair removal unit (30) and a skin cooling unit (10), wherein the skin cooling unit (10) has a skin contact surface (11), and the skin cooling unit (10) is equipped to apply an application substance (80) onto the skin by way of the skin contact surface (11) during use of the hair removal device. In addition to the cooling of the skin by means of contact cooling, a further cooling effect may also be achieved in such a hair removal device in that an application substance is applied, which contributes to the cooling of the skin, for example, by means of evaporation. The hair removal device may comprise a removable attachment, which also comprises at least the skin.

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract: A series of implementations of open access sleeves for holding one or more closed containers of sterile fluid for use in medical procedures are disclosed. The open access sleeves may be adapted to provide heat to maintain the containers of sterile fluid above the ambient air temperature of the room. The provision of heat may be controlled by a control system. The control system may use a temperature measurement device to obtain a temperature representative of the container of sterile fluid and of the sterile fluid in the container. The access sleeve may be included in a device for maintaining an open volume of sterile fluid within a range of a target temperature to maintain the closed containers of sterile fluid at a temperature near target temperature for open volume of sterile fluid.

Abstract: According to the present invention, there is provided a method of treating meibomian gland dysfunction in a mammal wherein an occlusion blocks at least a portion of the flow of naturally occurring secretion out of a gland channel orifice. The invention comprises selecting a device capable of delivering a jet of heated medium. The device is positioned such that when the jet is it is applied to the exterior surface of the eyelid, proximate to the gland channel orifice, a jet of heated medium is applied to the exterior surface of the eyelid proximate to the gland channel orifice at a pressure of from about 2 psi to about 30 psi. Application of the jet of heated medium is maintained for sufficient time to loosen, break up, fracture, soften or liquefy at least a portion of the occlusion such that at least a portion of the occlusion is removed. In an exemplary embodiment, the medium is water heated to a temperature of between about 42° C. and about 46° C.