Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. Systems for performing these methods with monitored flow rate and independent of patient height relative to the pressure source are also disclosed.

Abstract: A system for integrating at least one object with an animal within a research facility comprises at least one animal within the research facility, the at least one animal having a first tag associated therewith that is configured to communicate with a data management system. The system further includes at least one laboratory object having a second tag associated therewith and being associated with the at least one animal, the second tag being configured to communicate with the data management system. Still further, the system includes at least one technician badge having a third tag associated therewith, the badge configured to communicate with the data management system. The at least one animal, the at least one laboratory object, and the at least one technician badge are configured to transmit information to the data management system.

Abstract: Disclosed is a device for stimulating the tracheobronchial air of a patient suffering from an obstructive ventilatory disorder and able to modify the rheology of his tracheobronchial mucus, which includes a negative pressure generator, a physiological interface able to interface the device with the patient's respiratory apparatus, a connection pipe connecting the physiological interface to the negative pressure generator, and a control circuit capable of controlling the negative pressure generator, during the passive expiration phase, for the application of a succession of alternation of negative pressure and venting impulses with a determined frequency and a duty cycle determined during a first part of an expiration cycle and then a second frequency and a second duty cycle during a second part of the expiration cycle and to reiterate a defined number of expiration cycles.

Abstract: A subject is prescribed short and long acting insulin medicament regimens. When a qualified fasting event occurs, the basal insulin sensitivity estimate of the subject is updated using (i) an expected fasting blood glucose level based upon the long acting insulin medicament dosing specified by the long acting regimen during the fasting event, (ii) glucose measurements contemporaneous with the fasting event and (iii) a prior insulin sensitivity factor. A basal insulin sensitivity factor curve is calculated from the updated basal insulin sensitivity estimate. A bolus insulin sensitivity estimate of the subject is updated upon occurrence of a correction bolus with a short acting insulin medicament using (i) an expected blood glucose level based upon the correction bolus, (ii) glucose measurements after occurrence of the correction bolus, and (iii) a prior insulin sensitivity factor. A bolus insulin sensitivity factor curve is calculated from the updated bolus insulin sensitivity estimate.

Abstract: The present invention relates to a supplementary device a supplementary device for a manually operable injection device. The supplementary device has a body defining a passage through which an injection device is slidable, and a securing unit to secure the body to the injection device in the specific position when the injection device is received through the passage.

Abstract: An infusion pump includes a pumping mechanism having at least one sensor and a pump motor and a pump control subsystem configured to control operation of the pumping mechanism, the pump control subsystem including a processor, a memory, and a startup module configured to drive the pump motor at a first rate, receive input from the at least one sensor, and drive the pump motor at a second rate based on the input received from the at least one sensor. Startup algorithms command an infusion pump to reach a targeted delivery rate or steady state in minimal time without requiring priming of the pump line or otherwise engaging in known methods of pump startup analysis.

Abstract: A suction discharge unit of a suction discharge device includes a first unit and a second unit. The second unit controls the pressure inside the first unit. The first unit includes a storage chamber and a water sealing chamber. The water sealing chamber includes a first chamber communicating with the storage chamber, and a second chamber is sealed from the first chamber by sealing water. A negative pressure control unit is disposed in the second chamber. The negative pressure control unit includes a liquid retaining part retaining a liquid, a control member including control holes, and a support tube supporting the control member. The negative pressure control unit controls the pressure of the first chamber by causing gas to flow from the second chamber into the first chamber via the control holes and the liquid based on the pressure of the second chamber and the pressure of the first chamber.

Abstract: This disclosure describes a system, a method, and a computer program that enable auditing reported amounts of infused medications at a medical facility. In one embodiment, a computer receives packets transmitted over a communication network, where the packets include data related to activity of infusion pump systems at the medical facility. The computer performs deep packet inspection (DPI) of the packets, and extracts, from results of the DPI, values that include dosages of medications delivered to patients during treatment sessions using the infusion pump systems. The computer calculates, based on the values, amounts of the medications that were provided to the patients during the treatment sessions (actual amounts). Additionally, the computer receives amounts of the medications reported as being provided to the patients during the treatment sessions (reported amounts). The computer forwards a result of a comparison between the actual amounts and the reported amounts.

Abstract: A pump device, tube device and method for the aspiration, peristaltic movement and collection of fluid. A rigid tube for drawing fluid connected to a primary flexible tube. The primary flexible tube inserted through a peristaltic pump.

Abstract: An artificial pancreas system includes a continuous glucose monitoring device, a drug delivery device configured to exchange data with the continuous glucose monitoring device and containing a control algorithm, and possibly a remote controller configured to exchange data with the drug delivery device. The algorithm contains an insulin-glucose model, but is decoupled mathematically from the insulin injected by the user to offset the ingested carbohydrates. The control algorithm is designed to calculate two versions of insulin-on-board-patient-facing insulin-on-board (PFIOB) and system-facing insulin-on-board (SFIOB) to properly parse boluses and inform the system of only the insulin that is intended for high glucose correction, but not carbohydrate offsetting.

Abstract: Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.

Abstract: System and methods are provided for harvesting one or more organs, e.g., a lung from a donor body. In one embodiment, a distal end of a tubular member is introduced into the donor body's vasculature via a percutaneous access site, and the tubular member is manipulated until the distal end of the tubular member is disposed within the thoracic duct. Fluid is removed from the thoracic duct through the tubular member to a location exterior to the patient's body, and one or more organs are removed from the donor body. Optionally, one or more parameters within the thoracic duct or other parameters of the donor body may be monitored and fluid removal may be adjusted to reduce fluid accumulation within the one or more organs.

Abstract: A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.

Abstract: A logging device adapted to be attached to a pen drug delivery device (210) and capture a property value related to the dose amount of drug expelled from the drug delivery device during an expelling event, the logging device comprising a bore in which a snap lock with a flexible wire portion is arranged circumferentially in the bore, the wire being adapted to be moved laterally by a projection on the pen device and subsequently snap inwardly when the pen device is inserted axially in the bore. In this way an axial snap lock is provided between the logging device and the drug delivery device.

Abstract: Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.

Abstract: A reduced pressure treatment system includes a porous pad positioned at a tissue site and a canister having a collection chamber, an inlet, and an outlet. The inlet is fluidly connected to the porous pad. A reduced pressure source is fluidly connected to the outlet of the canister to such that fluid from the tissue site may be drawn into the collection chamber. A hydrophobic filter is positioned adjacent the outlet to prevent liquid from exiting the collection chamber through the outlet. A baffle is positioned within the canister to create a tortuous path between the inlet and the outlet to prevent premature blocking of the hydrophobic filter.

Abstract: A system for stimulating the healing of tissue comprises a porous pad positioned within a wound cavity, and an airtight dressing secured over the pad, so as to provide an airtight seal to the wound cavity. A proximal end of a conduit is connectable to the dressing. A distal end of the conduit is connectable to a negative pressure source, which may be an electric pump housed within a portable housing, or wall suction. A canister is positioned along the conduit to retain exudates suctioned from the wound site during the application of negative pressure. A controller for automated oscillation of pressure over time is provided to further enhance and stimulate the healing of an open wound. A power management motor control for varying pump drive frequency and managing a portable power supply is provided to increase battery life and improve patient mobility.

Abstract: A structure, method, and computer program product for a diabetes control system provides, but is not limited thereto, the following: open-loop or closed-loop control of diabetes that adapts to individual physiologic characteristics and to the behavioral profile of each person. An exemplary aspect to this adaptation is biosystem (patient or subject) observation and modular control. Consequently, established is the fundamental architecture and the principal components for a modular system, which may include algorithmic observers of patients' behavior and metabolic state, as well as interacting control modules responsible for basal rate, insulin boluses, and hypoglycemia prevention.

Abstract: A platform accessible by a user from a web browser/HMO's electronic medical record (EMR) for providing the user with information regarding a patient's drug regimen as well as generating alerts concerning potential adverse effects to a patient from taking a cluster including a plurality of pharmaceutical preparations and various food supplements/herbals may be in data communication with and configured to obtain information from at least two databases and at least one tool for processing the cluster of pharmaceutical preparations in accordance with the information to generate the alerts to the user.

Abstract: An apparatus comprises receiving a user prompt in a blood glucose (BG) management device to start a determination of an effective correction factor, receiving sampled blood glucose data of a patient obtained during a specified time duration, including a time duration after delivery of an initial insulin correction bolus, determining the effective correction factor using the BG management device according to a determined decrease in the blood glucose level of the patient and an amount of insulin in the initial insulin correction bolus, and cancelling the determination of the effective correction factor if a blood glucose level of the patient is outside of a specified range of blood glucose levels.

Abstract: An infusion pump includes a pumping mechanism having at least one sensor and a pump motor and a pump control subsystem configured to control operation of the pumping mechanism, the pump control subsystem including a processor, a memory, and a startup module configured to drive the pump motor at a first rate, receive input from the at least one sensor, and drive the pump motor at a second rate based on the input received from the at least one sensor. Startup algorithms command an infusion pump to reach a targeted delivery rate or steady state in minimal time without requiring priming of the pump line or otherwise engaging in known methods of pump startup analysis.

Abstract: The invention relates to a vacuum treatment array having at least one open-pored contact element, by way of which a negative pressure and/or suction can be generated in a body cavity, wherein the open-pored contact element is configured, at least in sections, in the manner of a tube, having an outer and/or inner boundary surface rotating around a tube axis, at least in part.

Abstract: An apparatus comprising a pump, a user interface, and a controller communicatively coupled to the pump and the user interface. The controller is adapted to receive information relating to a blood glucose level of a user, determine whether the blood glucose level differs from a target blood glucose level by a threshold value, and selectively provide or delay provision of an alert notifying the user to check the user's blood glucose level. Other devices, systems, and methods are disclosed.

Abstract: An apparatus comprising a pump configured to deliver insulin, an input configured to receive blood glucose data, a user interface, and a controller communicatively coupled to the pump, the input, and the user interface. The controller includes a blood glucose data module to compare the blood glucose data to a target blood glucose level for an insulin pump user. The controller is configured to present a question related to the blood glucose level via the user interface when the blood glucose level is different than the target blood glucose level, receive a response to the question via the user interface, and present a recommended user action based at least in part on the response. Other devices, systems, and methods are disclosed.

Abstract: Disclosed are a method, device and system for determining a flow rate of an excretion stream within an excretion collection assembly. According to some embodiments of the present invention, one of the constituent elements of the collection assembly includes a sensing module which includes an electrical and/or electromechanical component.

Abstract: Interventional catheter assemblies and components providing improved operational control of interventional catheters and/or operating heads of interventional catheters are provided. In general, controllers incorporate at least two operator selectable control features for controlling operation of the interventional catheter and/or an operating head, and are housed independently of the interventional catheter operating systems and other control systems, which may be provided in a housing located or locatable at a proximal region of the interventional catheter. The controller may be both dockable in and removable from the housing, and is operable in both a docked condition and a removed condition, providing flexibility and mobility in operational control during an interventional procedure.

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a user in accordance with an operating mode involves obtaining operational information pertaining to one or more prior instances of the operating mode, obtaining status information pertaining to the infusion device, and determining a diagnosis time based at least in part on the operational information. The diagnosis time is prior to a subsequent instance of the operating mode. At the diagnosis time, the method automatically determines the viability of the subsequent instance of the operating mode based at least in part on the status information and automatically generates a notification indicative of a recommended action for the user based at least in part on the viability.

Abstract: A medicament delivery device comprises a housing, a holder within the housing for receiving a medicament cartridge, a piston rod for driving a bung of the medicament cartridge, a drive mechanism including a motor for providing an output drive to the piston rod for delivering the medicament and control means for controlling operation of the device. The device is additionally provided with a bung sensor for sensing when the piston rod is in contact with the bung and the control means is operative for advancing the drive of the piston rod towards the bung.

Abstract: A system and method for providing updates to medical devices is disclosed. In one example, the medical devices are configured to pull update files in response to the reception of an update message from a server. Once the update files are downloaded by a medical device, the update files can be installed. While the medical device pulls the update files, the medical device can continue with its normal operation. If desired, a user can select which medical devices should be updated, based on any desired factors, such as the physical location of the device, the model of the device, the type of device, and the way the device is being used.

Abstract: The present disclosure relates to an infusion control valve adapted to be actuated by a valve actuator. The present disclosure further relates to an infusion valve actuator adapted to actuate an infusion control valve upon being triggered by an authentication unit. Furthermore, the present disclosure relates to methods for the administration of a substance.

Abstract: An ambulatory infusion device for infusion of a liquid drug into a patient's body over an extended period of time and methods thereof are disclosed. The device includes a sensor assembly, which produces a sensor assembly output based on an infusion characteristic of the ambulatory infusion device and based on a supply voltage/current, and a supply unit which is coupled to a sensor of the sensor assembly and generates the supply voltage/current. A sensor testing unit detects a failure of the sensor assembly, wherein the sensor testing unit is coupled to the sensor assembly and the supply unit, and the sensor testing unit carries out a sensor testing sequence. The sensor testing sequence includes controlling the supply unit so as to produce a variation of the supply voltage/current, and determining whether the variation of the supply voltage/current produces a corresponding variation of the sensor assembly output.

Abstract: An ultrafiltration (“UF”) evaluation method includes: (i) determining an amount of UF removed from a patient over a first dwell time; (ii) determine an amount of UF removed from the patient over a second, different dwell time; (iii) determining an amount of UF removed from the patient over a third, different dwell time; and (iv) fitting a curve to the UF removal amounts for the first, second and third dwell time. A peritoneal dialysis therapy generation method using the curve determined according to the “UF” evaluation method to generate at least one peritoneal dialysis therapy regimen.

Abstract: A digitally controlled aspirator is provided with a processor that allows the user to select operating conditions including one or more default settings. The processor further includes sensors for sensing operational and environmental conditions and adjusts the operation of the aspirator to reflect the sensed conditions.

Abstract: Provided are systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure source provides negative pressure to a wound dressing and positive pressure to an actuator that expels fluid from a fluid reservoir.

Abstract: Here provided are systems and methods for monitoring bladder and/or abdominal pressures, and a bladder function recovery device. In the systems and methods, the bladder pressure can be detected in real time with a bladder pressure detection unit that is communicated with a urinary catheter. In addition, the abdominal pressure can also be obtained in real time according to the corresponding relationship between the bladder pressure and the abdominal pressure. Furthermore, the bladder function recovery device can be used for bladder function recovery for patients in need.

Abstract: An injection device includes a dispensing chamber, a plunger, a controller, a temperature control device, and a memory device. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The controller controls the operation of the injection device. The temperature control device at least partially surrounds the dispensing chamber. The memory device has a parameter stored on it. The controller uses the parameter from the memory device to operate the injection device.

Abstract: A device for regulating cerebrospinal fluid in a cerebrospinal fluid space includes a cerebrospinal conduit having a distal end for insertion into the cerebrospinal fluid space in fluid communication with the cerebrospinal fluid. An actively oscillatably changeable sealed fluid volume can be in fluid communication with the cerebrospinal conduit. The changeable sealed fluid volume can be in a sealed fluid path extending to the distal end of the cerebrospinal conduit and is capable of actively oscillating in a changing fluid volume size for oscillating the cerebrospinal fluid in and out of the distal end of the cerebrospinal conduit and cerebrospinal fluid space.

Abstract: Devices, systems, and methods for treatment of an eye alter aspiration flow from the eye in response to an occlusion of the aspiration conduit pathway. Where aspiration is drawn from the eye using a volumetric pump, the pump can be reversed so as to induce fluid reflux from the aspiration conduit pathway into the eye to help clear the occlusion. The pump may vary the reverse flow in response to sensed aspiration pressure or the like, and the reverse flow may be halted before the pressure within the aspiration conduit pathway adjacent the eye significantly exceeds the irrigation fluid pressure and/or the pressure within the eye. Reflux may alternatively be generated by modulating a vent valve disposed between an irrigation conduit pathway and the aspiration conduit pathway.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump.

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Abstract: An apparatus 100 for use in tube feeding comprises a cylindrical body 110 provided with a first opening 120 and a second opening 130 connected by a flow channel 140. The body 110 comprises reagent 111, for determining a characteristic of fluid disposed in the body and a transparent window 112 through which the reagent 111 is visible. In use, a first end of an internal feeding tube releasably engages with the first opening 120. The second, distal end of said feeding tube is disposed inside a patient to be fed. A second feeding tube engages with the second opening 130. The second feeding tube connects the apparatus 100 to a bi-directional pump operable: to pump internal fluid from a reservoir, through the apparatus and into the internal feeding tube; and to pump fluid from the patient into the body 110 of the apparatus 100. This allows a user to pump fluid from the patient into the body 110 of the apparatus 100 to react with the reagent 111.

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Abstract: An internal tourniquet and method for establishing hemostasis within a portion of a limb to facilitate surgery controls flow of a fluid into a capsule surrounding substantially all of a human joint. Blood concentration in the capsule is sensed; and pressure in the capsule is controlled to maintain a fluid pressure in the capsule within a predetermined pressure tolerance window. The concentration of blood in the capsule is maintained below a predetermined maximum concentration while the fluid pressure is within the pressure tolerance window.

Abstract: Provided is a pericardial-liquid level control system with which a good viewing field can be ensured for an endoscope image without causing cardiac tamponade. A pericardial-liquid level control system is employed, including a sheath that is inserted into the pericardium; pumps that supply and expel liquid to and from the sheath; electrocardiogram electrodes that detect electrocardiographic information; and a pump control device that, in synchronization with the electrocardiographic information detected by the electrocardiogram electrodes, controls the pumps so that the liquid is supplied to the pericardium via the sheath during contraction of the heart and the liquid is expelled from the pericardium via the sheath during expansion of the heart.

Abstract: A pressure and a vision regulation method and device for irrigation of a body cavity (1), in which an inflow liquid pump (2) pressurizes the irrigation liquid in a feed line (13) and an outflow device (3) or an external suction source (20) drains the irrigation liquid from the body cavity (1) through a tubing (16) into a waste container (17). A control unit (4) controls either the inflow liquid pump (2) only or both the inflow liquid pump (2) and the outflow device (3) depending on an inflow irrigation liquid pressure from a pressure sensor (5). The method and the device are combined with a method for detecting blood cells, red blood cells, haemoglobin and/or debris in liquid coming from a surgical site to provide an automatic control and rinsing system with clear vision in the viewing area of the operational site.

Abstract: The invention relates to a device for reducing pressure variations in a fluid flowing in an aspiration branch of a surgical system, which pressure variations are generated by a pump that delivers in a non-continuous manner in the active operating state, with a diffuser arrangement which is arranged, in the aspiration branch, upstream of the pump in the direction of flow of the fluid. The invention also relates to a surgical system, in particular an ophthalmic microsurgical system for lens surgery.

Abstract: An intelligent automatic peritoneal dialysis device injects a dialysate accommodated in a dialysate container into a live animal via an input duct, elicits a waste liquid from the animal via an output duct, and concentrates the waste liquid in a waste liquid container. A flow direction control valve controls the flow direction of the dialysate and the waste liquid during the overall peritoneal dialysis treatment process.

Abstract: A method of irrigating a surgical site and aspirating fluid from the surgical site. The method includes directing a fluid through an aspiration conduit in a phacoemulsification hand piece using a vacuum pressure created from a pump in the hand piece interfacing with the aspiration conduit and directing an irrigation fluid through an irrigation conduit in the hand piece using a pressure created from the pump interfacing with the irrigation conduit. The method also includes increasing an irrigation fluid flow through the irrigation conduit by activating the pump in the hand piece, detecting a pressure associated with a surgical site using a sensor, and controlling intraocular pressure (IOP) by adjusting the pump speed based on the detected pressure.

Abstract: The disclosed devices and methods provide for the minimization of fluid extravasation during use of infusion catheters such as peripherally inserted central catheters and central venous catheters. The anti-extravasation catheter allows a surgeon to drain fluids from soft tissue surrounding an infusion site while also providing fluid inflow to a patient.

Abstract: A whole blood collection system includes an automated pump/control unit and an accompanying disposable blood set. When combined and connected to a source of anticoagulant, these elements allow automatic priming of the blood set with anticoagulant and automatic collection of anticoagulated blood product according to three different collection modes. The unit's pump and the blood set are specially designed to cooperate during the collection process to assure that the collected product has a precise blood to anticoagulant ratio. During the collection procedure, the pump/control unit automatically collects data relating to the procedure. Additional data specifically identifying components of the blood set, such as the blood collection bag, along with identification data on the donor's registration form may be scanned into the pump/controller unit by a scanner associated with the unit; this facilitates positive sample identification and tracking.