Abstract: A phacoemulsification system for operating a surgical handpiece having a handpiece; an irrigation fluid source for supplying irrigation fluid to the eye; an aspiration source coupled to the handpiece in order to aspirate the irrigation fluid from the eye through the handpiece; and a controller for controlling a vacuum in the handpiece, the controller comprising: a sensor for sensing the vacuum in the handpiece; an occlusion parameter, the occlusion parameter being a vacuum level corresponding to an occlusion of the handpiece or a flow rate corresponding to an occlusion of the handpiece; a maximum allowable vacuum level in the handpiece, the maximum allowable vacuum level having at least a first predetermined level; and a trigger value that is set based in part on the occlusion parameter.

Abstract: A post-occlusion chamber collapse canceling system for a surgical apparatus that detects the breaking of occlusions by tissue fragments in the distal end of the aspiration path and produces a response consisting in a transitory blockage of the distal end the aspiration path to terminate the chamber collapse and a transitory venting of the aspiration line to relieve the vacuum, in a way that post-occlusion chamber collapses are cancelled.

Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Abstract: Systems and methods for fluid control during aspiration. In an embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.

Abstract: A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; an irrigation pressure sensor located at or along the pressurized irrigation fluid source or irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on a reading from the irrigation pressure sensor and an estimated flow value modified by a compensation factor.

Abstract: A contrast liquid injector has a controller that calculates a necessary volume of the contrast medium based on a read out necessary dose of effective component per unit weight, weight of the subject, and concentration of the effective component. The injection rate of a base-operation condition is changed based on the calculated necessary volume of the contrast medium, wherein the predetermined injection time is unchanged, for all volumes of the contrast medium, when making the injection pattern, whereby a timing of an optimum concentration of the contrast medium will be substantially unchanged for all volumes of the contrast medium.

Abstract: A catheter includes an elongated tubular body including a first wall and second wall defining first and second lumens, respectively. Each wall extends to a distal end and defines a distal opening. The first and second walls may each include one or more side openings disposed proximal of the distal end. The first and second lumens are separated by a septum. The septum includes a septum extension extending distally from the septum. The septum extension is adapted to articulate relative to the septum in response to fluid flow into and out of the distal openings of the first and second lumens. The septum extension is dimensioned to partially obstruct fluid flow into the catheter through one of the distal openings upon the articulation of the septum extension.

Abstract: The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.

Abstract: The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.

Abstract: An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. A method, system, and an article of manufacture for automatically detecting an occlusion in a medication infusion pump is provided. The electrical current to an infusion pump is measured. Based on measurements of one or more variables, the infusion pump detects whether there is an occlusion in the system. The methods of detecting occlusions may be dynamic.

Abstract: A system is for thermal ablation and includes (a) a heating element heating an ablation fluid flowing through an ablation device and to a target region of a body and (b) a computing arrangement controlling power supplied to the heating element supplying power to heat the ablation fluid to a desired temperature. The computing arrangement reduces the supplied power when a detected ablation fluid temperature exceeds a desired temperature and increases the supplied power when the detected ablation fluid temperature is below the desired temperature. The computing arrangement monitors a percentage of heat supplied by the heating arrangement to heat the fluid to the desired temperature as a function of a maximum amount of heat which the heating element is capable of supplying.

Abstract: An environmentally sensitive hydrogel material swells or collapses in response to a parameter such as pH level associated with consumption of food by a patient. This swelling or collapsing is harnessed to treat morbid obesity or some other condition of the patient. The swelling or collapsing of the hydrogel may be used to tighten a gastric band or gastric valve when the patient starts eating; then loosen the band or valve when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to increase the size of a space occupying device in the patient's stomach when the patient starts eating; then decrease the size of the space occupying device when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to selectively restrict the absorption of nutrients within a patient's gastrointestinal tract, such as in the duodenum.

Abstract: A pressure and a vision regulation method and device for irrigation of a body cavity (1), in which method an inflow liquid pump (2) pressurizes the irrigation liquid in a feed line (13) and in which an outflow device (3) or an external suction source (20) drains the irrigation liquid from the body cavity (1) through a tubing (16) into a waste container (17) and in which a control unit (4) controls either the inflow liquid pump (2) only or both the inflow liquid pump (2) and the outflow device (3) depending on an inflow irrigation liquid pressure from a pressure sensor (5), where the first control unit (4) compares the inflow irrigation liquid pressure and flow with pressures calculated to correspond to pressure in the body cavity for the respective flow for a nominal surgical site and that a matching between the calculated values and the inflow irrigation liquid pressures is made by altering the effect of either the inflow liquid pump (2) only or the inflow liquid pump (2) and/or the outflow device (3) and/or

Abstract: A fluid delivery system comprises a pump configured to deliver a therapeutic agent to a patient, a memory storing a therapy program defining the delivery of the therapeutic agent to the patient by the pump and a default infusion schedule based on the therapy program, and a processor configured to control the pump to deliver the therapeutic agent to the patient according to the therapy program, to determine an error condition that prevents the pump from continuing to deliver therapy according to the therapy program, and, upon determination of the error condition, to control the pump to deliver the therapeutic agent to the patient according to the default infusion schedule.

Abstract: A dual pump irrigation/aspiration pump system capable of operating in a plurality of different modes suitable for a variety of different endoscopic surgical procedures. The system monitors actual or calculated intra-articular pressure and adjusts flow to maintain surgeon requested pressure at the surgical site while controlling outflow. The irrigation/aspiration pump system has an inflow pump and tubing dedicated to communicating fluid to the surgical work site and an outflow pump and tubing dedicated to removing fluid from the work site at a controlled rate. The system further has different size inflow and outflow pumps and tubing cassettes, means for altering the outflow fluid flow rate to accommodate a surgical tool and a means for declogging the surgical tool in the event of blockage. In a preferred embodiment a pressure control system provides inferred pressure information representative of the pressure at the work site.

Abstract: A system includes (i) a needle for insertion into a port of an implantable infusion device, and (ii) a receiver apparatus having a port location signal receiver module capable of receiving a signal from the implantable infusion device regarding spatial orientation of the port. The system further includes a processor operably coupled to the receiver apparatus and capable of determining the orientation of the needle relative to the port based on the received signal. The system also includes a display operably coupled to the processor. The processor is configured to cause the display to graphically render trajectory of the needle relative to the port. The port is graphically rendered as a target structure having a reference area. The needle is graphically rendered as an object moveable relative to the target structure. Occupation of the reference area by the object indicates trajectory alignment of the port and the needle.

Abstract: A blood volume control method has been developed including: monitoring a condition of a patient (such as hematocrit (Hct)), wherein the condition is indicative of blood volume in the patient; automatically determining that the condition indicates a low blood volume in the patient; automatically infusing an infusion solution into the patient in response to the determination of a low blood volume, and automatically adjusting the infusion to maintain the monitored condition at a predetermined value.

Abstract: A fecal diverting device includes an internal balloon formed at the inside of a tubular body part disposed at the front end of a connection tube, at least one external balloon formed at the outside of the tubular body part, and an enema liquid injection hole formed through the forefront of the tubular body part and the at least one external balloon and an enema liquid to be injected into an intestinal tract of a patient via an enema liquid injection hole through a control tube. A device controller connected to the control tube regulates the amounts of fillers filling the internal balloon and the at least one external balloon and controlling the injection of the enema liquid, supplied from an enema liquid supplying unit, into the intestinal tract.

Abstract: A method of providing hypothermia to a patient including the steps of inserting a fluid delivery member into a peritoneal cavity of the patient; delivering hypothermia fluid from a fluid source into the peritoneal cavity through the delivery member; and limiting fluid pressure within the peritoneal cavity without providing feedback control to the fluid source. The invention also provides an apparatus for practicing the method.

Abstract: Improved sensors and sensing methods for detection of Neuromuscular Blockade (NMB), for example to improve monitoring generally, as well as facilitate automated NMB drug administration. The methods, systems, devices, etc., herein can increase the quantity and quality of data available. The methods, etc., include translation between commonly available sensing types, use of partially saturated sensor measurements, use of a model of neurotransmitter storage and release and sophisticated use of more than one sensor simultaneously. These methods are aided by new sensors and methods of decreasing electrical noise. An implementation of the methods, systems, devices, etc., herein is automated drug delivery for NMB, whether through an advisor system or through with full computer control.

Abstract: A device and a method for a peritoneal dialysis treatment having several cycles include a cycler controlled by a processor. The cycler fills the abdominal cavity with dialysis fluid, and drains the abdominal cavity. A sensor senses a variable related to the draining of the dialysis fluid. The draining is interrupted when the variable reaches a breakpoint at which the variable is radically changed, thereby leaving the residual volume of fluid.

Abstract: The disclosure provides an apparatus and methods for removing thrombosis in vessels. The apparatus includes a sheath catheter combined with an aspiration catheter. The sheath catheter includes a first sheath opening in a proximal end of the sheath catheter, a second sheath opening in a distal end of the sheath catheter, a first balloon disposed on an outer surface of the distal end of the sheath catheter, and a passageway extending between the first and second sheath openings. The aspiration catheter is configured to pass through the first and second sheath openings and the passageway of the sheath catheter. The aspiration catheter includes a second balloon, a plurality of infusion ports, and an aspiration port disposed on an outer surface of a distal portion of the aspiration catheter. A relative position between the sheath catheter and the aspiration catheter controls the number of unblocked infusion ports.

Abstract: A fluid management system for use with a fluid reservoir includes an inflow pump and an outflow pump. The inflow pump is connectable to a probe for delivering a distention fluid to a body cavity. The outflow pump removes the distention fluid through the same probe, thus establishing a re-circulating volume of distention fluid within the body cavity. The removed fluid is filtered and returned to a fluid reservoir for eventual recycling to the body cavity. A controller adjusts the flow rates of the inflow pump and the outflow pump to maintain a pre-selected fluid pressure or volume within the body cavity.

Abstract: Surgical fluid management systems and methods of operating surgical fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.

Abstract: The present invention relates to a balloon catheter system for draining and/or supplying fluid from/into hollow organs, body cavities or cysts, comprising a conduit catheter with an open distal end, a hollow needle guided in a separate guide conduit and a balloon surrounding the catheter stem at the distal end of the conduit catheter. The conduit catheter with the hollow needle can be inserted from outside into the hollow organ via a guide catheter, into the body cavity or cyst, the balloon can be filled with filling medium via the hollow needle through an opening formed in the guided duct and provided in the lumen of the balloon, and it can be fixed in the hollow organ, body cavity or cyst. The hollow needle can be removed from the guide duct after filling the balloon. The balloon and the conduit catheter remain in the hollow organ, body cavity or cyst.

Abstract: In general, this disclosure relates to techniques for sealing, or pinching, high-pressure fluid tubing (e.g., braided tubing) that may be used to deliver medical fluid from a powered medical fluid injection device, such as an injector that delivers contrast media and/or saline during angiographic or computed tomography (CT) procedures. In some cases, one or more low-friction, solenoid-based pinch valve mechanisms may be used. One example powered medical fluid injection device comprises an injector head and at least one pinch valve mechanism that is coupled to the injector head. The at least one pinch valve mechanism comprises a plunger, a reciprocating arm driven by the plunger, and a tube pinching area. The at least one pinch valve mechanism, when deactivated by the injector head, is configured to cause the reciprocating arm to pinch fluid tubing that runs through the tube pinching area.

Abstract: A surgical fluid management system delivers fluid for distending a uterine cavity to allow cutting and extraction of uterine fibroid tissue, polyps and other abnormal uterine tissue. The system comprises a fluid source, fluid deliver lines, one or more pumps, and a filter for re-circulating the distension fluid between the source and the uterine cavity. A controller can monitor fluid retention by the patient.

Abstract: The present invention provides a compact colon irrigation device and a method for performing human colon irrigation. The colon irrigation device of the present invention comprises at least a housing, a gravity tank to supply water by gravity, a means for filling the gravity tank with warm water, an extension tube extending vertically from the top of the gravity tank to create a required water head for providing substantially a constant gravity flow of water at a predetermined pressure, a speculum for insertion into rectum of colon for irrigation and extracting matter, a water supply line extending from the gravity tank connected with the said speculum, and a drain line connected with the said speculum. The gravity tank provides water at a pressure suitable for carrying out the colon irrigation safely.

Abstract: The present invention provides a highly effective device and method for performing human colon irrigation. It comprises a bypass line having a non-return valve connected to a warm water supply line where in the non-return valve operates in proportion to back pressure as it develops in the colon thereby allowing gentler filling of colon and limiting pressure in the colon to a maximum safe level. Benefits include patient comfort and a safeguard against damaging the intestine. The present invention also provides a novel housing for a colon irrigation device which provides easy access to the internal part of the device without the need for disconnecting water or electrical supply lines.

Abstract: In an infusion circuit (1), a peristaltic pump (7) displaced the infusion fluid along a line (3), sourcing it from a batch container (2). When a weight sensor (5) detects an emptying of the batch container (2), the pump is halted. If on stopping the pump the pressure measured by a sensor (6) operating in an expansion chamber (4) does not drop in excess of a predetermined threshold with respect to a non-empty container (2), a non-secure situation is signalled, due to an excessive quantity of air in the expansion chamber.

Abstract: A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug deliver pump.

Abstract: The tube coupling, which is capable of connecting two injectors with different sizes, includes a tube body and a tube connector. The tube body is hollow and has a coupling end and a check valve. The tube connector is coaxially connected to the coupling end of the tube body and has a joint portion. The joint portion has a passage communicating with the tube body. The check valve flexibly closes the passage from the tube body. A diameter of the passage fits a first injector with a first size, and an outer diameter of the joint portion fits a second injector with a second size.

Abstract: Visceral fat may be removed from a subject using a cannula that has an interior cavity and an orifice configured to permit material to enter the cavity. This is accomplished by generating a negative pressure in the cavity so that a portion of the tissue is drawn into the orifice. Fluid is then delivered in pulses, via a conduit, so that the fluid exits the conduit within the cavity and impinges against the portion of the tissue that was drawn into the orifice. The fluid is delivered at a pressure and temperature that causes the visceral fat to soften, liquefy, or gellify, without damaging the subject's internal organs that are in the vicinity of the visceral fat. The visceral fat that has been softened, liquefied, or gellified is then suctioned away.

Abstract: A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner.

Abstract: A liquid injector stores data of operating conditions of a liquid injection mechanism for regions to be imaged, and also stores data of schematic images of a plurality of body sections and schematic images of regions to be imaged in association with each other. The liquid injector displays the schematic images in the shape of a human body. When one of the schematic images of the corresponding regions is selected, the liquid injector reads the data of corresponding operating conditions, and controls operation of the liquid injection mechanism according to the read operating conditions. When the operator manually selects one of the schematic images of the body sections and then manually selects one of the schematic images of the corresponding regions, the liquid injector automatically injects a contrast medium into the subject under operating conditions corresponding to the selected region to be imaged.

Abstract: A motorized injection and aspiration system and methods for its use, where the motorized injection and aspiration system comprises (a) a syringe coupled to a needle, wherein the syringe includes a plunger, (b) a cannula, (c) a tube having first and second ends, wherein the first end is coupled to the needle and the second end is coupled to the cannula, (d) a syringe driver to drive the plunger, (e) at least one foot pedal, (f) a step motor, and (g) a control unit in communication with the step motor, the syringe driver and the at least one foot pedal.

Abstract: A system for the movement of fluids into and out of a surgical field is provided with a control module manipulated by a user; a valve controlled by the user via the control module, the valve controlling flow of a fluid; and a tube set having a proximal branch and a distal branch, wherein the proximal branch is opened and closed by the valve and at least a portion of the distal branch being flexible and a distal tip of the distal branch configured for manipulation within a surgical field. The valve is disposed at a distance to the surgical field and allows free access to tube by the user. Separate proximal branches for suction, irrigation, and insufflation are provided. One or more distal branches may be provided.

Abstract: Systems and methods for cleaning body cavities are presented. Some embodiments reduce size of fecal matter pieces within an evacuation conduit. Some comprise devices and methods for purging an evacuation conduit. Some comprise reduced cross-sectional profiles of a cleaning device. Some protect intestinal tissue by preventing exposure to excessively high and low pressures.

Abstract: A device for delivery of glucose-regulating medication, particularly insulin, depending on the measured tissue glucose concentration, having a sensor for measuring the glucose concentration in tissue fluid, possibly a unit for removing fluid from subcutaneous tissue, as well as a container for the glucose-regulating medications, having a unit for subcutaneous delivery of the glucose-regulating medications, and having a unit connected to the glucose sensor for regulating the quantity of the glucose-regulating medication to be delivered depending on the measured tissue glucose concentrations. The device simulates the function of the natural pancreas and is constructed small and compact.

Abstract: An ingestible capsule is provided for delivering medication to a subject. A capsule coating dissolves in a gastrointestinal tract of the subject. An inner core of the capsule has an outer surface associated therewith. The outer surface is disposed within the coating and expands when the coating dissolves. A medication is disposed on the outer surface, and the outer surface is configured such that the medication contacts an intestinal wall of the subject when the outer surface expands. Other embodiments are also provided.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease. Means for solving problems The cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).

Abstract: An ophthalmosurgical measuring device (100) has an irrigation line (4) through which irrigation fluid (3) can be transported and an aspiration line (7) through which aspiration fluid can be transported to a suction pump (8). The ophthalmosurgical measuring device also includes a sensor (10) with which a differential pressure between irrigation line (4) and aspiration line (7) can be detected.

Abstract: To facilitate imaging of a patient two different image recording methods are to be carried out at the same time. An auxiliary fluid, for example a contrast medium or a tracer, may be introduced into the body in each image recording method. The invention proposes mixing the two auxiliary fluids in situ immediately before dispensing to the patient. For this purpose it provides an injector with which the auxiliary fluids may be mixed and supplied to the patient. Devices for controlling dispensing of fluid from containers connected to the injector to produce a mixed solution may be electronically controlled by a control unit which calculates the total quantities, and optionally sub-quantities, of auxiliary fluids, which are used for a mixed solution, before activating the devices.

Abstract: An ophthalmic surgical apparatus for use with an eye including a tube adapted to be in fluid communication with the eye, a pressure sensor adapted to measure an intraocular pressure value of the eye, a fluid reservoir comprising a moveable wall, the fluid reservoir adapted to be in fluid communication with the eye through the tube, and at least one processor coupled to the pressure sensor to receive the measured intraocular pressure value, the at least one processor operable to position the moveable wall in response to a difference between the measured intraocular pressure value and a target intraocular pressure value.

Abstract: The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 24, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a handpiece 50 applied to a surgical area for infusing irrigation fluid and for aspirating a biological material, conduits 60 and 62 connecting the handpiece to each of the source of irrigation fluid and the collection cassette and means 70 for isolating the pump from the handpiece to prevent creation of vacuum within the conduit 62 and the collection cassette 30 after receiving a stop signal.

Abstract: In one embodiment of the invention, a robotic surgical instrument is provided for the control of flows of one or more fluids into and out of a surgical site. The robotic surgical instrument may include a housing, a flow control system, a hollow tube, and one or more hose fittings. The housing to couple the instrument to a robotic arm. The flow control system mounted in the housing includes one or more controlled valves to control the flow of one or more fluids. The hollow tube has a first end mounted in the housing coupled to the flow control system. A second end of the hollow tube has one or more openings to allow the flow of fluids into and out of the surgical site. The hose fittings have a first end coupled to the flow control system and a second end to couple to hoses.

Abstract: Some embodiments an infusion pump system can be used to determine a user's total insulin load (TIL) that provides an accurate indication of the insulin previously delivered to the user's body which has not yet acted. In particular embodiments, the TIL can account for both the bolus deliveries and the basal deliveries that have occurred over a period of time. Such information may be useful, for example, when the infusion pump is operated in conjunction with a continuous glucose monitoring device.

Abstract: An atherolysis catheter comprises a catheter body and one or more isolation balloons. A distal section of the body comprises infusion and aspiration ports in fluid communication with infusion and aspiration lumens for delivering and collecting fluids. A pump delivers infusate through the infusion lumen, and a valve in the infusion port controls release of the infusate into a target location in the vasculature.

Abstract: A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person.