Filter Or Series Thereof For Liquid Entering Or Leaving Container Patents (Class 604/406)
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Patent number: 8202493Abstract: The present invention includes a harvesting and irrigation device, a method and a kit for the collection of viable fat cells and/or adipose tissue with decreased handing and improved yield and viability.Type: GrantFiled: March 19, 2009Date of Patent: June 19, 2012Assignee: Genesis Biosystems, Inc.Inventor: Brian Buss
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Patent number: 8167863Abstract: A vented vial adapter has a filter attached to a vent arm that includes at least two filter media for suppressing aerosolized medicaments from leaving the vial and suppressing bacteria and other contaminants from entering the vial during reconstitution activities of the medication in the vial. The filter media allows the passage of air to the atmosphere outside the vial for pressure equalization. In another aspect, a third filter medium is used in the vent of the adapter to allow gas to pass in either direction through it, but prevents bacteria and particulate matter in the atmosphere from reaching the second filter device. A first filter is hydrophobic and prevents non-dispersed liquid from reaching the second filter, while conducting liquid dispersed in gas. The second filter absorbs the liquid dispersed in gas.Type: GrantFiled: October 16, 2006Date of Patent: May 1, 2012Assignee: CareFusion 303, Inc.Inventor: D. Gregory Yow
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Patent number: 8152738Abstract: An apparatus and method that may be used for collecting target cells or tissue and preparing a cell block are disclosed.Type: GrantFiled: March 20, 2007Date of Patent: April 10, 2012Inventors: Rongshan Li, Wu Li
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Publication number: 20120065610Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: ApplicationFiled: September 30, 2011Publication date: March 15, 2012Inventors: John M. Seifert, Thomas F. Fangrow
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Patent number: 8128611Abstract: A pre-assembled medical fluid flow system and method of making same are disclosed. The system includes a first sterilized fluid flow system component, a second sterilized fluid flow system component and a flow path for providing fluid communication therebetween. The flow path includes an isolated portion. An openable closure isolates the isolated portion from the first sterilized fluid system component, and a microorganism filter is disposed between and isolates the isolated portion of the flow path and the second sterilized fluid flow system component. Therefore, fluid from the isolated portion of the flow path must flow through the microorganism filter to reach the second sterilized fluid flow system component.Type: GrantFiled: December 3, 2008Date of Patent: March 6, 2012Assignee: Fenwal, Inc.Inventors: Walter Timothy Watts, Kyungyoon Min, Daniel Martin Karlovsky
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Patent number: 8052667Abstract: The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis.Type: GrantFiled: September 7, 2005Date of Patent: November 8, 2011Assignee: Velico Medical, Inc.Inventors: Keith Rosiello, Henrik Clausen
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Patent number: 7993531Abstract: Biological fluid filtration methods are provided for the treatment of gas within a biological fluid filtration system. A quantity of biological fluid is flowed under the force of gravity through a leukocyte removal filter and into a post-filter container. The post-filter container has a maximum vented volume that is approximately the same as the quantity of biological fluid flowed through the filter and into the post-filter container. At least a substantial portion of the gas in the post-filter container is vented therefrom without separately restricting expansion of the post-filter container and without manually manipulating the post-filter container to expel gas.Type: GrantFiled: April 7, 2008Date of Patent: August 9, 2011Assignee: Fenwal, Inc.Inventors: Anthony Oleszkiewicz, Bryan Blickhan, Mark B. Jones
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Publication number: 20110190723Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.Type: ApplicationFiled: April 13, 2011Publication date: August 4, 2011Inventor: Thomas F. Fangrow
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Publication number: 20110178493Abstract: One end of a tubular portion (16) is sealed with a stopcock (5) that is fitted in the tubular portion (16). A first flow channel (33) and a second flow channel (36) are formed in the stopcock (5). A first hole (37), a second hole (43), a third hole (38), and a fourth hole (44) are formed in a connector main body (2). Switching between a setting that brings an inner space (16a) of the tubular portion (16) into communication with the first hole (37) via the first flow channel (33) and a setting that brings the inner space (16a) of the tubular portion (16) into communication with the second hole (43) via the first flow channel (33) and brings the third hole (38) into communication with the fourth hole (44) via the second flow channel (36) can be achieved by rotating the stopcock (5).Type: ApplicationFiled: November 13, 2009Publication date: July 21, 2011Applicant: JMS CO., LTD.Inventor: Tadashi Okiyama
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Patent number: 7971728Abstract: A filtration system for collecting bone fragments during surgery performed on a patient includes a cylinder having a rotating disk with circumferential arms extending radially in the cylinder to define pockets. The rotating disk includes a longitudinal hub that carries an outlet connected to a central passageway formed in the disk. A plurality of apertures on the disk permit the liquid to flow into the passageway and through the outlet while the pockets retain the bone fragments. The disk is rotated to align circumferential spaced pockets to align with the inlet and outlet ports. The disks includes bearing surfaces that permit the rotation thereof and the arms are spaced from the cylinder inner surface to allow the flow of fluid in the event the pockets fill and clog the apertures and prevent flow into the outlet passage.Type: GrantFiled: February 28, 2006Date of Patent: July 5, 2011Assignee: The Anspach Effort, IncInventors: Thomas D. Anspach, Stephen M. Bucina
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Publication number: 20110160701Abstract: An apparatus for removal of premixed drugs or reconstitution of lyophilized drugs and for the injection of the reconstituted drug into the patient. The apparatus includes a syringe assembly and an adapter assembly that can be removably connected to a medicament container containing a premixed drug or lyophilized medicament. The syringe assembly of the apparatus includes a liquid chamber between the forward end of the body portion and the piston and a syringe cannula assembly. The syringe cannula assembly, which can be removably interconnected with the body portion, comprises a cannula support and a hypodermic needle sealably connected to the cannula support. The adapter assembly comprises an adapter preferably molded from a moldable plastic that includes a top wall, an adapter cannula connected to and extending from the top wall and a variety of connectors connected to the top wall for removably interconnecting the adapter with the medicament container.Type: ApplicationFiled: December 13, 2010Publication date: June 30, 2011Inventors: Philip Wyatt, Gary Schaeffer, Claude Vidal, Wendy Elizabeth Wyatt
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Publication number: 20110028908Abstract: A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.Type: ApplicationFiled: March 26, 2010Publication date: February 3, 2011Applicant: MEDRAD, INC.Inventors: Arthur E. Uber, III, Mark Trocki, Frederick W. Trombley, III, Kevin P. Cowan
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Patent number: 7867214Abstract: In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.Type: GrantFiled: July 17, 2003Date of Patent: January 11, 2011Assignees: Baxter International Inc., Baxter Healthcare S.A.Inventors: Robert W. Childers, David S. Brown, Ramesh Wariar, Sujatha Karoor, Shahid Din, Leo Martis, Cody Buchmann, Paul Soltys
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Patent number: 7854845Abstract: Biological fluid filtration systems including biological fluid filtration devices capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system includes a mechanism to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device. Both single sided and double sided biological fluid filtration devices are disclosed, including double sided biological fluid filtration devices with a solid partition wall with a first independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining mechanisms include vent filtration devices, diaphragm draining devices, and biological fluid filtration devices that include an integral diaphragm.Type: GrantFiled: September 3, 2004Date of Patent: December 21, 2010Assignee: Hemerus Medical LLCInventor: Peter Zuk, Jr.
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Patent number: 7820434Abstract: A novel apparatus and device is described for reconstituting a bone sample with a biological fluid, such as concentrated plasma or saline solutions, for example, prior to surgical implantation into a patient. In particular, the invention comprises, in certain aspects, a container in which a bone sample may be reconstituted with the desired fluid by applying a vacuum within the container, thereby driving the fluid into the bone for complete, or near complete, permeation of the fluid into the interstices of the bone sample prior to surgical implantation.Type: GrantFiled: March 10, 2006Date of Patent: October 26, 2010Assignee: Orogen Biosciences, Inc.Inventors: Robert Brandt, Michael Buzenius
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Publication number: 20100234824Abstract: Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.Type: ApplicationFiled: March 15, 2010Publication date: September 16, 2010Applicant: ROCHE DIAGNOSTICS INTERNATIONAL AGInventors: Huwiler Christoph, Kuhni Florian, Geipel Andreas
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Patent number: 7776021Abstract: Methods and materials for making an apparatus which duplicates the functionality of a physiological system id provided.Type: GrantFiled: November 5, 2004Date of Patent: August 17, 2010Assignees: The Charles Stark Draper Laboratory, Massachusetts Institute of Technology, The General Hospital CorporationInventors: Jeffrey T. Borenstein, Eli Weinberg, Brian K. Orrick, Eleanor M. Pritchard, Edward J. Barnard, Nicholas J. Krebs, Theodore Marentis, Joseph P. Vacanti, Mohammad Reza Kaazempur-Mofrad
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Publication number: 20100198183Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.Type: ApplicationFiled: December 30, 2009Publication date: August 5, 2010Applicant: DEKA Products Limited PartnershipInventors: Richard J. Lanigan, Bright Chong Khuang Foo, Dean Kamen
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Publication number: 20100198182Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.Type: ApplicationFiled: December 30, 2009Publication date: August 5, 2010Applicant: DEKA Products Limited PartnershipInventors: Richard J. Lanigan, Bright Chong Khuang Foo, Dean Kamen
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Patent number: 7762976Abstract: An apparatus for extracorporeal oxygenation of a patient's blood during cardiopulmonary bypass surgery. The apparatus comprises a bubble sensor, arranged at or connected to a venous line, for detecting bubbles in the venous blood received from the patient. When air bubbles are detected, a second pump is activated to draw air from an air chamber provided in an air filter connected to the venous line and arranged downstream of the bubble sensor. A first pump draws the blood from the air filter and supplies the blood to an oxygenator and to the patient via an arterial line.Type: GrantFiled: January 20, 2005Date of Patent: July 27, 2010Assignee: Sorin Group Deutschland GmbHInventors: Johann Schreyer, Erwin Knott, Andreas Hahn
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Patent number: 7757724Abstract: An improved medication dispensing device includes an apyrexia receptacle, a transport pipeline, a perfusion device, a filter, and a dispensing needle, which operates in an environment in compliance with Class 100 laminar air ventilation. The perfusion device erected at the middle of the transport pipeline which has two ends linking to the apyrexia receptacle and the filter, respectively. In operation, the perfusion device pumps the prepared medication solution from the apyrexia receptacle to get through the filter to remove particles and bacterium, and a thin tubular dispensing needle which punctures the rubber plug of an aseptic bottle. An axial groove rendered in middle section of the dispensing needle forms a pressurized seal part with the rubber plug resiliently wrapped around at the middle of the dispensing needle to discharge redundant air pressure accumulating in the aseptic bottle while keeps outside air from entering.Type: GrantFiled: July 20, 2006Date of Patent: July 20, 2010Assignee: Institute of Nuclear Energy ResearchInventors: Ming-Hsin Li, Wuu-Jyh Lin, Cheng-Hung Chien, Jun-Chieh Tsai, Wun-Shen Lan
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Publication number: 20100168712Abstract: A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.Type: ApplicationFiled: May 24, 2007Publication date: July 1, 2010Applicant: BAYER HEALTHCARE LLCInventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, John Peter Palmer-Felgate, Matthew Burgess Avery, Kevin George Skinner, Chris Kadamus, Lee Wood, Peter Schwan, Ben Arlett
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Patent number: 7744580Abstract: A device and a procedure for the extemporaneous preparation of an individual quantity of sterile treatment fluid that may be compressible, in particular a treatment gas, the device comprising a rigid cartridge (3) with an outlet valve, an administration syringe (4) and a filtration-type connection/sterilization device (5, 6). The cartridge (3) simply contains an individual quantity of treatment fluid under pressure, and the cylinder of the syringe (4) is adapted to contain this individual quantity.Type: GrantFiled: February 5, 2004Date of Patent: June 29, 2010Assignee: ArcadophtaInventor: Gerard Reboul
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Patent number: 7743799Abstract: A vial adapter is described comprising a housing, the housing comprising an expandable chamber to contain a volume, an internal passage in communication with the expandable chamber, at least one opening in communication with the internal passage, and an access member integral with the housing. A hollow spike comprising a proximal end is integral with the housing and a distal end. The spike comprises a vent lumen open at the distal end and a fluid lumen open at the distal end, the vent lumen is in communication with the internal passage and the fluid lumen is in communication with the access member. A first check valve restricts communication from the expandable chamber to the internal passage, and a second check valve restricts communication from the internal passage to the opening. Methods of reconstituting and/or withdrawing hazardous material using the vial adapter are described.Type: GrantFiled: November 6, 2006Date of Patent: June 29, 2010Assignee: Industrie Borta S.p.A.Inventors: Theodore J. Mosler, Bryan J. Peters, Scott P. Jarnagin
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Patent number: 7736516Abstract: A filter for the removal of substances from blood product has a porous element of a polymeric material consisting of a polyether-ester copolymer or of a polymer blend comprising said copolymer.Type: GrantFiled: July 1, 2004Date of Patent: June 15, 2010Assignee: Fresenius Hemocare Italia S.r.l.Inventors: Laura Zambianchi, Paolo Bonaguidi, Giorgio Mari
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Publication number: 20100137826Abstract: A pre-assembled medical fluid flow system and method of making same are disclosed. The system includes a first sterilized fluid flow system component, a second sterilized fluid flow system component and a flow path for providing fluid communication therebetween. The flow path includes an isolated portion. An openable closure isolates the isolated portion from the first sterilized fluid system component, and a microorganism filter is disposed between and isolates the isolated portion of the flow path and the second sterilized fluid flow system component. Therefore, fluid from the isolated portion of the flow path must flow through the microorganism filter to reach the second sterilized fluid flow system component.Type: ApplicationFiled: December 3, 2008Publication date: June 3, 2010Inventors: Walter Timothy Watts, Kyungyoon Min, Daniel Martin Karlovsky
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Publication number: 20100130957Abstract: Described is a collapsible fluid reservoir that may be expanded during use and collapsible to lie substantially flat when not in use. According to one embodiment, a collapsible fluid reservoir can include a substantially non-rigid container having a substantially open proximal end and a substantially sealed distal end opposite the proximal end defining a cavity therein, wherein the distal end includes at least one fluid outlet port extending therethrough. The collapsible fluid reservoir can also include a substantially rigid cap affixed to the proximal end of the non-rigid container and including at least one fluid inlet port extending therethrough and in fluid communication with the cavity.Type: ApplicationFiled: November 23, 2009Publication date: May 27, 2010Applicant: Smisson-Cartledge Biomedical LLCInventors: Hugh F. Smisson, III, David C. Field, Christopher W. Menard, Brandi L. Bohleber, Hiywot Yilma
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Patent number: 7708889Abstract: A method used in connection with processing of blood components, wherein blood products are then filtered via a filter rotating along with a centrifuge rotor and the sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products.Type: GrantFiled: January 26, 2009Date of Patent: May 4, 2010Assignee: CaridianBCT, Inc.Inventors: Niclas Högberg, Emanuel Hällgren, Peter Pihlstedt, Brian M. Holmes, Lars Persson, Lars Strandberg, Geert Van Waeg, Frank Corbin, III
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Patent number: 7686797Abstract: An improved biological fluid filtration system is shown having, seriatim, a blood container, a biological fluid filtration device downstream of the blood container, and a blood receiving container downstream of the biological fluid filtration device; a bypass line is provided to allow fluid communication between the blood container and the blood receiving container, the bypass line includes a loop, the loop of the bypass line being configured to be disposed above the blood container at a sufficient height to prevent the passage of fluid around the leukocyte depletion device; the loop of the bypass line being disposed in a tube support device, the tube support device being configured to support substantially the entire weight of the biological fluid filtration system without substantially crimping said bypass line.Type: GrantFiled: March 31, 2006Date of Patent: March 30, 2010Assignee: Hemerus Medical, LLCInventors: Majid Zia, Anthony J. Angelo, Craig M. Wilson
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Publication number: 20090326506Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.Type: ApplicationFiled: June 19, 2007Publication date: December 31, 2009Applicant: Nipro CorporationInventors: Mitsuru Hasegawa, Atsushi Ishikawa, Suguru Oyagi, Takeshi Ohguro
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Patent number: 7621298Abstract: A recipient has a body designed to contain a fluid and an orifice by which the fluid may be introduced into the body. The recipient is equipped with a system for the sterile transfer of the fluid from inside the body. The transfer system comprises a deformable and impervious wall, wherein the wall is positioned with respect to the recipient so that it forms a closed and sterile space inside which the orifice is located, a fluid communication device between the closed space and the outside of the recipient, wherein the device may be handled without compromising the sterility, and a seal structure associated with the orifice, wherein the seal structure is at least partially located inside the closed space so that it may be moved between an open position and a closed position of the orifice.Type: GrantFiled: October 24, 2007Date of Patent: November 24, 2009Assignee: Maco Pharma, S.A.Inventors: Francis Goudaliez, Thierry Verpoort
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Patent number: 7601268Abstract: The invention is directed to a system for continuously filtering a blood product including whole blood or any of its component(s), erythrocytes, leukocytes, platelets and plasma either alone or in combination. The system includes a connector for receiving the blood product, a filter coupled to the connector for filtering the received blood product, a collection bag coupled to the filter for collecting the filtered blood product, and a reservoir bag connected to the connector for temporarily storing received blood product, and providing received blood product through the connector to the filter to maintain continuity in filtration. The reservoir bag and the collection bag are suspended, the connector near or below the bottom of the collection bag, and the bottom of the reservoir bag is above the bottom of the collection bag. Also provided is a method of filtering a blood product using the continuous blood filtration system.Type: GrantFiled: May 27, 2003Date of Patent: October 13, 2009Assignee: Haemonetics CorporationInventor: Michael Ragusa
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Patent number: 7591812Abstract: The invention is a closed complaint venous reservoir with at least one pliable wall having at least three innovative features: 1) the venous reservoir incorporates means that purge gas bubbles entering the venous reservoir without the user intervention, 2) the venous reservoir incorporates a cardiotomy reservoir, and 3) the pliable wall of the venous reservoir is sealed within a rigid housing allowing control of its “atmospheric” pressure, and therefore the pressure at which that wall collapses. The combination of the three innovative features provides a collapsible compliant reservoir unitized with cardiotomy reservoir having air removal features and enabling vacuum augmented venous drainage (VAVD) that match that of the open hardshell venous-cardiotomy reservoir unit, while retaining the advantages of the closed soft shell venous reservoir.Type: GrantFiled: July 24, 2006Date of Patent: September 22, 2009Inventor: Yehuda Tamari
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Patent number: 7588562Abstract: A fluid collection apparatus is provided that includes a housing configured for receipt of fluid and/or tissue for collecting fluid therefrom. A holder is configured with the housing to receive an evacuated tube. The holder can include a needle hub supporting a needle cannula in fluid communication with a port extending into a fluid well of the housing. A sloped bottom surface of the housing directs fluid to the fluid well. A sidewall extension or support component extends downward beyond the sloped bottom surface to allow the housing to be stood upright on a flat surface. In certain embodiments, the apparatus includes a tubular cavity to provide a recessed location of the needle cannula for preventing accidental needle injuries. An optional cap provides further shielding from needle cannula and safely maintains fluid in housing after use.Type: GrantFiled: March 25, 2004Date of Patent: September 15, 2009Assignee: Tyco Healthcare Group LPInventors: Mary Jo. A. Toomey, Bradley M. Stewart, Lee C. Burnes, Eugene E. Weilbacher
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Patent number: 7588732Abstract: The present invention includes a harvesting and irrigation device, a method and a kit for the collection of viable fat cells and/or adipose tissue with decreased handing and improved yield and viability.Type: GrantFiled: March 25, 2005Date of Patent: September 15, 2009Assignee: Genesis Biosystems, Inc.Inventor: Brian Buss
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Publication number: 20090216212Abstract: A vial adaptor configured to be attached to a wide range of vial sizes, the adaptor being configured to penetrate the vial seal so that the contents of a vial can be removed. The vial adaptor can have a body portion, a penetrating portion projecting from the body portion and configured to be inserted through the seal and positioned within an interior space of the vial so that the contents of the vial can flow through an opening in the penetrating portion, an interface portion supported by the body portion that is connectable to a syringe or other medical implement, at least one deflectable tab configured be bendable by hand or to bend in response to contact with the vial. The vial can also have a filtered air vent to allow air to fill the vial as the contents thereof are being removed.Type: ApplicationFiled: February 18, 2009Publication date: August 27, 2009Applicant: ICU MEDICAL, INC.Inventor: Thomas F. Fangrow, JR.
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Patent number: 7569026Abstract: A bag connection comprises a first bag, a tube having a blood-drawing needle at the front end, a plurality of second bags, tubes for connecting the first and second bags, and tubes and branch connectors for connecting the second bags to each other. On the other hand, a filter unit includes a filter, and a tube connected at opposite ends thereof to the inlet and outlet of the filter. The tubes of the bag concatenation and the tube of the filter unit have respective markers attached thereto. With these markers used as marks, both tubes are aseptically connected by a tube aseptic connection device, thereby incorporating the filter unit into an intermediate portion of a tube of the bag concatenation.Type: GrantFiled: September 29, 2004Date of Patent: August 4, 2009Assignee: Terumo Kabushiki KaishaInventor: Hiroyuki Sugawara
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Publication number: 20090159485Abstract: A kit comprising a medical dispensing container (402), such as a vial for diagnostic agents, and a liquid transfer device (401) to be used to transfer a liquid into or from said dispensing container. The transfer device allows substantially limiting the gaseous exchange between the inside of a vial and the external ambient, when the device is connected to the vial in steady state conditions.Type: ApplicationFiled: December 5, 2006Publication date: June 25, 2009Applicant: Bracco Research S.A.Inventors: Laurent Jakob, Frederic Rivas
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Patent number: 7507217Abstract: A device for exchanging and/or docking functional modules (1, 2), and used for the extracorporeal circulation of bodily fluids, is provided. Each functional module (1, 2) includes at least one conduit (3; 4) comprising an inlet (5; 7) and an outlet (6; 8). The aim of the invention is to exchange the functional modules of an extracorporeal circuit as rapidly as possible, without detaching tubular connections and without having to establish a new connection. The invention is provided with elements (9, 10; 11, 12) for connecting the conduit (3) of a first functional module (1) to the inlet (5) and the outlet (6) of a second functional module (2). The connection is established in such a way that the first functional module (1) is bypassed by means of the second functional module (2) to maintain the flow and the bodily fluid is diverted through the second functional module (2).Type: GrantFiled: March 9, 2005Date of Patent: March 24, 2009Assignee: PPA Technologies AGInventor: Markus Ferrari
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Patent number: 7497944Abstract: A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separated in a chamber and then filtered via a filter rotating along with a centrifuge rotor, wherein the filter is located closer than the chamber to an axis of rotation of the rotor. The filter may include a porous filtration medium configured to filter leukocytes, platelets, and/or red blood cells. Some examples include a pressure sensor sensing pressure of pumped blood components. The sensed pressure may be used in connection with controlling the pumping of the blood products and/or in connection with determining the location of an interface associated with the blood products. Other uses of the sensed pressure are also possible.Type: GrantFiled: March 27, 2007Date of Patent: March 3, 2009Assignee: CaridianBCT, Inc.Inventors: Niclas Högberg, Emanuel Hällgren, Peter Pihlstedt, Brian M. Holmes, Lars Persson, Lars Strandberg, Geert Van Waeg, Frank Corbin, III
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Patent number: 7488312Abstract: A screen for use with a fluid/specimen collector and a combination screen and fluid/specimen collector for collecting and trapping patient specimen(s) during a medical procedure comprising a collecting trap for receiving fluid/specimen(s) therein, a lid, an intake member for transferring fluid/specimen(s) from a patient into the collecting trap, and a waste exit member. The screen of the invention comprises an insert member capable of being placed within the lid of the fluid/specimen collector. The insert member includes an intake aperture, enabling the intake member to extend through to transfer fluid/specimen(s) from a patient into the collecting trap. The insert also includes a plurality of straining apertures capable of allowing excess fluid to pass through and exit the collector through the waste exit member while preventing specimens from passing through the straining apertures, thus trapping these specimens within the collector for easy retrieval for subsequent medical testing.Type: GrantFiled: November 2, 2005Date of Patent: February 10, 2009Inventors: Joann E. Rogers, Marcia Caldwell
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Patent number: 7429325Abstract: A device (2) for a body fluid bag, includes a filtering part (5) and a retransfusion part (6), the filtering part (5) having a filtering part inlet opening (7) and a filtering part outlet opening (8). The outlet opening (8) is arranged to be connected to an inlet opening of the body fluid bag, and the retransfusion part (6) has a retransfusion part inlet opening (10), being arranged to be connected to an outlet opening of the body fluid bag, and a retransfusion part outlet opening (11), wherein the filtering part (5) and said retransfusion part (6) are mechanically integrated to form a single unit. A transfusion unit (16) including such a device (2) is also disclosed.Type: GrantFiled: March 24, 2004Date of Patent: September 30, 2008Assignee: Hammarplast Medical ABInventor: Henrik Ingvarsson
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Publication number: 20080208117Abstract: An infusion system utilizes a solution reservoir divided into a first section and a second section which are fluidly isolated but volumetrically connected such that introduction of a pumping fluid into the first section of the reservoir causes displacement and flow of a solution out of the second section of the reservoir. The use of a separate reservoir, separation member, and delivery tubing allow for significantly decreased loss of feeding solution and the like due to dead volume.Type: ApplicationFiled: October 19, 2007Publication date: August 28, 2008Inventors: Christopher P. Steinman, Jason A. Bultman
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Patent number: 7413665Abstract: A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.Type: GrantFiled: December 15, 2006Date of Patent: August 19, 2008Assignee: Gambro BCT, Inc.Inventors: Brian M. Holmes, Johan-Petter Hagström, Per-Olov Lundberg, Geert Van Waeg, Peter Nordgren
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Patent number: 7396451Abstract: A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.Type: GrantFiled: December 15, 2006Date of Patent: July 8, 2008Assignee: Gambo BCI, Inc.Inventors: Brian M. Holmes, Johan-Petter Hagström, Per-Olov Lundberg, Geert Van Waeg, Peter Nordgren
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Publication number: 20080132874Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.Type: ApplicationFiled: November 1, 2007Publication date: June 5, 2008Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventor: Jane Emerson
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Patent number: 7364657Abstract: Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate mononuclear cells, which can then be delivered back near the cardiac tissue of the patient.Type: GrantFiled: March 31, 2005Date of Patent: April 29, 2008Assignee: Abbott Cardiovascular Systems Inc.Inventors: Evgenia Mandrusov, Albert K. Chin, William Earl Webler, Jr., Yan Shen, Robert D. Ainsworth, Eugene Michel
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Publication number: 20080097370Abstract: An improved medication dispensing device includes an apyrexia receptacle, a transport pipeline, a perfusion device, a filter, and a dispensing needle, which operates in an environment in compliance with Class 100 laminar air ventilation. The perfusion device erected at the middle of the transport pipeline which has two ends linking to the apyrexia receptacle and the filter, respectively. In operation, the perfusion device pumps the prepared medication solution from the apyrexia receptacle to get through the filter to remove particles and bacterium, and a thin tubular dispensing needle which punctures the rubber plug of an aseptic bottle. An axial groove rendered in middle section of the dispensing needle forms a pressurized seal part with the rubber plug resiliently wrapped around at the middle of the dispensing needle to discharge redundant air pressure accumulating in the aseptic bottle while keeps outside air from entering.Type: ApplicationFiled: July 20, 2006Publication date: April 24, 2008Inventors: Ming-Hsin Li, Wuu-Jyh Lin, Cheng-Hung Chien, Jun-Chieh Tsai, Wun-Shen Lan
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Patent number: 7361277Abstract: A filter device (100) comprising a filter (10) for producing a leukocyte-depleted plasma-rich fluid is disclosed.Type: GrantFiled: June 14, 2005Date of Patent: April 22, 2008Assignee: Pall CorporationInventors: Thomas J. Bormann, Gerard DelGiacco, Byron Selman
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Patent number: 7354758Abstract: Device and method for sterility testing, in particular of pharmaceutical products, includes a closed sterility test system having at least two test containers, in each case having an integrated test filter, an outlet connecting branch arranged below the test filter and an inlet connecting branch which is arranged above the test filter and can be connected with a tube connection via a sampling device to a sample container. The tube connection of the test container in each case has a distributing component via which a fixed tube connection to an associated nutrient medium container is formed and can be used to feed an associated nutrient medium to the test container.Type: GrantFiled: August 12, 2004Date of Patent: April 8, 2008Assignee: Sartorius Stedim Biotech GmbHInventors: Oliver Guenec, Eric Jallerat