Abstract: A collection device with double outputs and a method of using the same are provided.

Abstract: Sheets for use with medical containers are described. An example sheet for use with medical containers includes a plurality of layers. At least one of the layers includes polyolefin and the plurality of the layers comprises approximately less than 15% of at least one of a plasticizer or a low molecular weight material that is to decrease a rate of hemolysis when exposed to a blood component. At least one of the plurality of layers being modified to enable autoclavability and radio frequency sealability.

Abstract: A plurality of thin-wall parts (9a) of a sealant layer (7) are formed in a portion continuously changed in the interval of one sealing part (8) and a gas barrier layer (6) of other laminate film (4). At the inner circumferential side between the adjacent thin-wall parts (9a) and the thin-wall part (9a) at the innermost circumferential side and at the outer circumferential side of the thin-wall part (9a) of the outermost circumferential side, a thick-wall part (9b) of the sealant layer (7) is formed. All of the opposing sealant layers (7) between the two adjacent thin-wall parts (9a) are mutually heated and fused, so that an excellent adiabatic performance is maintained for a long period.

Abstract: The present invention relates to a plastic film (10) formed by a co-extrusion method, and an infusion bag formed thereof. The plastic film (10) includes at least three layers having: a first layer (1) constituted by a polyamide obtained by a ring-opening polymerization of a lactam having 11 or more carbon atoms or by polycondensing of an ?-amino acid having 11 or more carbon atoms, or a polyamide obtained by copolycondensing a dicarboxylic acid having 10 or more carbon atoms and a diamine having 6 or more carbon atoms; a second layer (2) containing a copolymer of an ?-olefin and an anhydride monomer of an unsaturated carboxylic acid or an unsaturated dicarboxylic acid as the major component; and a sealing layer (3) containing a polyethylene as the major component.

Abstract: A port device (10) for a fluid storage bag (46) comprises a housing (12) having a bottom wall (14) and opposing sidewalls (16, 18), and a connective opening (20) in said housing (12) opposite to said bottom wall (14). The connective opening (20) is adapted to be connected with said fluid storage bag (46) and has an elongate surface area shaped by a wide center portion (22) and peaked longitudinally opposing ends (24). A port device (10) further comprises at least one access port (26) in said bottom wall (14) adapted to communicate with the interior of said fluid storage bag (46) through said connective opening (20). In order to be fixable to the fluid storage bag (46) in a safe and easy manner, said port device (10) further comprises at least one bridge element (32) supporting said sidewalls (16, 18) and oriented transversely to the longitudinal direction (34).

Abstract: An air conditioning system includes a refrigerant evaporated in an outdoor heat exchanger. The refrigerant is drawn into a compressor in a state heated by a heater that includes a carbon nanotube heating element in a heating mode to more stably and efficiently perform heating.

Abstract: A blood or blood component collection and processing system, apparatus and method are disclosed. One embodiment includes a vascular access device and a blood collection container having a blood inlet and first and second blood component outlets. The outlets are located at opposite ends of the container, and a blood flow conduit extends between the vascular access device and collection container. The collection container is free of attachment to other blood collection containers when in an initial collection configuration at the time of collection.

Abstract: A flexible container for storing a liquid medicament and a device for the automated release of the liquid medicament from the flexible container are disclosed. The flexible container includes a wall and an access opening. The wall of the flexible container comprises two sheets of flexible material sealed together such that a storage volume intended to contain the liquid medicament is defined. The access opening provides a fluid connection to a conduit system in fluid connection with the storage volume via a fluid channel arranged between the storage volume and the access opening, wherein the fluid channel is formed by a cavity arranged on at least one of the two sheets.

Abstract: A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space.

Abstract: A cylindrical stopper for closing a medical system and a method for closing a medical system, and to the medical system itself, closed with the stopper of the invention.

Abstract: A container having multiple compartments formed by frangible seals in the interior chamber of the container is disclosed. The container comprises an indicator adapted to provide an indication that a seal breach between the chambers has occurred. Methods of forming a container having a seal breach detection indicator are also disclosed.

Abstract: A self-warming peritoneal dialysis solution bag is provided that contains a peritoneal dialysis solution. The solution bag can have an outer surface and a non-electric, warming patch adhered or affixed to the outer surface. The non-electric, warming patch can include an activatable agent that undergoes an exothermic reaction when activated. The warming patch can retain a sufficient amount of activatable agent to generate enough heat, upon activation, to warm the contents of the bag to at least 95° F. Warming patches that are separate from a peritoneal dialysis solution bag are also provided, as are kits for warming a peritoneal dialysis solution bag. Methods of warming a peritoneal dialysis solution bag with a non-electric, warming patch, are also provided.

Abstract: The present invention relates to pharmaceutical fluids, and more particularly to a flexible container for aseptic transfer and/or mixing of pharmaceutical fluids. A biocontainer for the transfer of pharmaceutical fluids includes a flexible layer divided by a fold line into a front face and a rear face. The layer is folded about the fold line such that the front face and the rear face are facing each other to define an interior space between them. The biocontainer also includes a seam that connects the front and rear faces to each other to close the interior space. A fill port is also provided to communicate with the interior space. This fill port is intersected by the fold line.

Abstract: A system for mixing the contents of a first container and a second container. The system includes the first container that has container body with an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening. The second container includes a port assembly including a port housing connected to the second container and a retainer constructed to connect to the first container. The retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing. The port assembly further includes an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing.

Abstract: Valve assemblies for use with a liquid container and a drug vial for enabling an initial transfer of liquid contents from the liquid container to the drug vial for liquid drug formation purposes and subsequent transfer of liquid drug contents from the drug vial to the liquid container for administration purposes. Liquid drug transfer sets can include a valve assembly pre-attached to a liquid container. Alternatively, liquid drug transfer sets can include a valve assembly packaged in sterile blister packaging ready for attachment to a liquid container prior to use.

Abstract: A flexible bag (1) that is partially filled with a basic liquid solution (21) has a first end closure (3) from which a mixing tube (7) extends that is provided with a frangible closure cap (8) and a terminal (9) that is suitable for the connection of a container (22) of active substance (23) to be mixed with the basic liquid solution (21) and a second end closure (5) from which two dispensing tubes (12, 13) extend that are provided with respective frangible closure caps (14, 15). A first dispensing tube (12) has a terminal (18) of the press type and a second dispensing tube (13) has a terminal (19) of the screw type (FIG. 1).

Abstract: The present invention relates to a disposable bag which comprises a multilayer film for accommodating a fluid, and a device which comprises a support holder for the disposable bag according to the invention in which the disposable bag is arranged. The present invention also relates to a process for the production of the disposable bag.

Abstract: The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.

Abstract: A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.

Abstract: A self standing bag having two side wall sheets and a bottom sheet. To flatten the bag, the bottom sheet is sandwiched between the two side wall sheets and symmetrically folded along a line parallel to its bottom edge, separating the bag into a four-layer part and a two-layer part. In the two-layer part, the bag includes first sloped sealing lines extending between a first two points on the top edges of the side wall sheets and spaced from the vertical side wall edges by a first distance, to a second two points spaced from the vertical edges of the side wall sheets by a second distance less than the first distance. The four-layer part includes second sloped sealing lines extending between the second two points and a third two points on the bottom edges of the side wall sheets.

Abstract: The present invention consists of a venous blood reservoir that has a separate blood chamber to filter vent blood and a separate chamber to filter sucker blood. The two blood chambers are separated by a common wall and are in fluid communication along their top assuring that vacuum applied to the top of either is equally applied to the other. A mean to form communication across the wall allows the user to either accumulate sucker blood in its chamber while letting vent blood to flow freely to the venous blood chamber. Alternately, user can let the blood in the sucker chamber to combine with the venous blood freely too.

Abstract: A connector according to the invention includes a first connection region for connecting a first container, a piercing element and a break-open element, wherein the piercing element has a first end section and a second end section and a channel, running from the first end section to the second end section, for transporting a medicinal active substance, wherein the first end section is formed for piercing a membrane of the first container connected in the first connection region, and, at the second end section, the break-open element is attached such that it can be broken open and/or broken off, wherein, in the attached state, the break-open element seals the channel of the piercing element in liquid tight fashion.

Abstract: The connector for a fluid line of an extracorporeal circuit comprises a tubular body which internally defines a fluid passage, a first connection port predisposed for coupling to the fluid line, a second connection port predisposed for coupling to a male Luer connector borne by an external element, and a closure element of the second connection port. The closure element is formed of a breakable membrane made in a single piece with the tubular body. On coupling, the membrane is broken by the truncoconical projection of the male Luer connector. The connector connects a service line of an extracorporeal circuit to a pressure sensor of a dialysis machine.

Abstract: A cap, especially a disinfectant cap, is for protecting and/or closing off the abdominal connector used in peritoneal dialysis, and to a detection device for peritoneal dialysis. There is a bag set for peritoneal dialysis and use thereof. In view of the sometimes serious consequences of an incorrect sequence of fluids in the patient's abdominal cavity, it is desirable to prevent an incorrect sequence of fluids during peritoneal dialysis. This is achieved by providing the cap, especially a disinfectant cap, with information about the medium contained at any one time in the patient's abdominal cavity. In this way it is always possible—even after the fluid has been dispensed into the abdominal cavity and the bag disposed of—to determine which medium is currently in the patient's abdominal cavity and/or to record other details, such as the amount, the concentration, the manufacturer, etc.

Abstract: Device (5) for filtering blood including a filter unit (7) having a blood filter, an inlet (8) for blood to be filtered and being connectable to an artery of a patient and a blood outlet (9) for filtered blood and being connectable to a vein of the patient, and having a filtrate container (6,14), that encloses the filter unit (7), for receiving filtrate (12) passing through the blood filter during a filtering process and that the filtrate container (6,14) is a closed container, which in a filled state is arranged to establish a counter-pressure over the blood filter, whereby the filtering process is interrupted. The invention also concerns a system including the above device.

Abstract: Containers for the storage of red blood cell compositions are disclosed. The container walls are made of a plastic composition that includes a polymeric material and at least one extractable agent that includes a terephthalate ester in an amount effective to suppress hemolysis in red blood cells.

Abstract: A dialysis bag is provided, including a first layer of film and a second layer of film each having a closed end and an opposite outlet end, the layers sealed together about corresponding peripheral edges to define a bag chamber. An outlet assembly is sealingly disposed at the corresponding outlet ends and has a tubular administrative outlet with an inlet and is in fluid communication with the bag chamber. A dimple is formed in at least one of the layers adjacent to the inlet for preventing occlusion as a fluid level decreases in the bag.

Abstract: A system for mixing contents of a first container with contents of a second container. The system includes a first container, a second container, a device for establishing fluid communication between the first container and the second container, and a hanger for hanging the system, wherein the hanger is operable only when fluid communication between the first container and the second container has been established. The system can be used in a method for preventing medication delivery errors.

Abstract: One aspect of the present disclosure relates to a bag for storing blood previously withdrawn from a subject. The bag can comprise a flexible, closed container and at least one removable heat transfer member adhered to an outer surface portion of the container. The container can include an inlet therein that forms part of the container. The inlet can be adapted for fluid-tight connection to a tube member through which the blood is caused to flow.

Abstract: An embodiment directed towards a system for ambulatory drug infusion over an extended time period from a flexible container is disclosed, and in which the system comprises a filling apparatus with a hollow support structure defining a container compartment, the container compartment being adapted to receive, fully or in part, the flexible container, and the support structure being adapted to limit the expansion of the flexible container by contacting the flexible container upon being filled, thus defining a maximum filling volume of the flexible container. In other embodiments, a container assembly is disclosed that comprises a flexible container and a support structure as well as use of a flexible container in or in combination with a system according to the invention or a container assembly according to the invention.

Abstract: A drug bag is housed inside a container, which has two shells movable between an open position and a closed position; and a gripper fitted outside the shells and defined by two jaws movable between a grip position and a release position to grip and release at least one conduit allowing access to the content of the bag.

Abstract: The present invention provides an apparatus comprising a housing and a flexible reservoir adapted to contain a fluid and having a septum member formed from a needle-penetratable self-sealing material. The flexible reservoir is arranged within the housing in combination with mounting means arranged within or formed by the housing, wherein the mounting means engages the septum member to thereby mount the flexible reservoir relative to the housing. In this way a secure fixation between the reservoir and the housing is provided without having to interfere with the general flexibility of the reservoir, e.g. substantially the entire flexible reservoir apart from the outlet/mounting means may be arranged free to move relative to the housing, this allowing the reservoir to be emptied to a high degree.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: It is an object of the resent invention to provide a multi-chamber container that has a weak seal portion having an increased joining strength and being easy to be opened when in administration of medicine, and that is provided at low cost. The multi-chamber container includes a medicine accommodation chamber 1, a diluting solution chamber 3 jointed to one side of the medicine accommodation chamber 1 via a partitioning weak seal portion 2, an unoccupied chamber 5 having a port 6 and joined to an opposite side of the medicine accommodation chamber 1 via a discharging weak seal portion 4, a film member 7 attached to the medicine accommodation chamber 1 for increasing a joining strength of each of the discharging weak seal portion 2 and the discharging weak seal portion 4, the discharging weak seal portion 4 having an easy-to-open portion 8 that enables the discharging weak seal portion 4 to easily opened therethrough.

Abstract: A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.

Abstract: The invention relates generally to implantable drug delivery devices. Devices having a single drug chamber configuration, a divided drug chamber configuration and a compact dual-drug configuration are described. The devices have features to prevent clogging of the dispensing catheter and the creation of a local vacuum caused by the dispensing of the drug fluid. Also provided are features of a failsafe refilling process, automatic refill notification, and performance verification process. The divided drug chamber configuration enables frequent or continuous minute doses. A dual-drug chamber configuration uses self-locking refill containers to prevent mismatching between refill containers and drug chambers.

Abstract: A liquid component collecting device capable of more easily collecting a liquid component. A liquid component collecting device (100) is provided with: a flexible cylindrical liquid component storage container (21) having an opening at one end thereof; a cylindrical first housing container (22) for housing the liquid component storage container (21) and having an opening at one end thereof; and a first cap (23) connected to the opening in the liquid component storage container (21) and fitted to the opening in the first housing container (22). A pressure regulating space (26) independent of the internal space of the liquid component storage container (21) is formed between the outer side of the liquid component storage container (21) and the inner side of the first housing container (22).

Abstract: A connector assembly includes a first connector having a tubular first connector body, a hollow needle inside the first connector body and a first sealing component piercable by the needle, and a second connector having a tubular second connector body and a second sealing component. The second sealing component is in the second connector body, is attached to a first piercing section when inserted into the first connector body, and, in that state, is pierced by the needle together with the first piercing section. The connector assembly also includes a restriction which, when the second connector is inserted into the first connector, temporarily interrupts and restricts the insertion operation, but allows resumption of such operation when the restriction is removed, and which, when the second connector is withdrawn from the first connector, temporarily interrupts and restricts the withdrawing operation, but allows such operation to resume when the restriction is removed.

Abstract: A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Abstract: The present invention relates to a plastic film for medical containers having an oxygen absorbing function including at least 4 layers (4) and formed by a co-extrusion method, and an infusion bag formed thereof, in which the 4 layers include: a first layer (1) constituted by a polyamide obtained by a ring-opening polymerization of a lactam 11 or more carbon atoms or by polycondensing of an ?-amino acid having 11 or more carbon atoms, or a polyamide obtained by copolycondensing a dicarboxylic acid having 10 or more carbon atoms and a diamine having 6 or more carbon atoms; a second layer (2) of a mixed composition that is adjacent to the first layer and contains an ethylene vinyl alcohol copolymer of an ?-olefin and a monomer of an unsaturated carboxylic acid or an anhydride of an unsaturated dicarboxylic acid as the major component, and a transition metal salt and a polyene-based polymer having an unsaturated double bond as accessory components; a third layer (3) that is adjacent to the second layer and contai

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A medical fluid container of a flexible plastic material is produced as follows: at first, a plastic compound is produced from a heterogeneous mixture of a first, lower-viscosity raw polymer component having a first melt viscosity and a second, higher-viscosity raw polymer component having a second melt viscosity which is greater than the first melt viscosity. Then the plastic compound is extruded. The extrudate is confectioned. Finally, the confectioned extrudate is sealed to form the finished fluid container. A film tubing may serve as intermediate product for the medical container. The medical container or the film tubing thus produced has surface structures with a typical average size of 15 to 200 ?m. The production method requires little effort while fulfilling demanding requirements with respect to the stability of the produced fluid container.

Abstract: A multi-chamber container of two liquid mixing type, aiming for obtaining an increased reliability for preventing an administration from being practiced under a non separated condition of a weak seal. The medical bag 10 has an outer peripheral strong seal 14 and a weak seal 18 for separating the space inside the medical bag into two partitions 20 and 22. At the tip end of an outlet port 12, a flap 28 as a valve member is provided, which usually closes the outlet port 12 to the space inside the medical bag. The flap 28 is connected to the opposite surface of the medical bag, so that the flap 28 is displaced in cooperation with an expansion deformation of the medical bag as obtained when the weak seal 18 is opened, resulting in opening of the outlet port 12. The flap is formed with a small hole 44 for limiting a liquid flow amount to a small value.

Abstract: The present invention relates to a connector for a replaceable container to be used in a medical machine, which is comprised by at least a body, the inner side of which is traversed by inlet and outlet tubes extending from within such container towards an outer side of the connector, wherein said tubes separately extend leading to two laterally spaced-apart apertures that are removably attachable to a mounting means and supplementary connection of said machine.

Abstract: Containers and components thereof for use in the medical industry and methods to manufacture the same are described. An example tab for use with a medical container includes opposing sheets sealed to define an open ended chamber into which a port is to be at least partially positioned. The port is to enable access to the medical container. The tab includes a tear seal defined by each of the opposing sheets and a first guide positioned on a first side of each of the tear seals. The tab includes a second guide positioned on a second side of each of the tear seals, wherein the first and second guides are to enable a tear to propagate substantially between the guides and adjacent the tear seals.

Abstract: Device (5) for filtering blood including a filter unit (7) having a blood filter, an inlet (8) for blood to be filtered and being connectable to an artery of a patient and a blood outlet (9) for filtered blood and being connectable to a vein of the patient, and having a filtrate container (6,14), that encloses the filter unit (7), for receiving filtrate (12) passing through the blood filter during a filtering process and that the filtrate container (6,14) is a closed container, which in a filled state is arranged to establish a counter-pressure over the blood filter, whereby the filtering process is interrupted. The invention also concerns a system including the above device.

Abstract: A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space.

Abstract: A multilayer plastic container for storing lyophilized products includes at least three layers consisting of inner and outer layers having a moisture vapor transmission rate of not more than 0.1 gm mil/100 sq. in.-day at 73° F. and 95% rh, and an intermediate layer of hygroscopic resin construction having a moisture content less than 1000 ppm. The hygroscopic intermediate layer preferably comprises at least 30% of the total thickness of the three layers. The inner and outer layers preferably are of cyclic olefin polymer or cyclic olefin copolymer construction, and the hygroscopic intermediate layer preferably is of amorphous nylon construction. The container preferably is empty and sealed within a secondary container, such as a metallized bag, that is impervious to moisture.

Abstract: A container for use in dialysis, containing a certain amount of a salt concentrate in the form of a powder, granules or tablets or mixtures thereof, having an inlet for the water and an outlet that is connectable to a dialysis machine. Both the inlet and the outlet are situated on one side of the container, and each includes a filter therein to prevent any undissolved salt concentrate from leaving the container.

Abstract: An irrigation source identification system includes an irrigation source, an imaging device, and a processor. The irrigation source includes a container for holding a quantity of irrigation fluid and a port fluidly coupled to the container. The port has an outlet end and a neck. The neck has a plurality of protrusions selected from a grouping of protrusions. The plurality of protrusions provides a unique identifier for the container. An imaging device images the neck and the plurality of protrusions of the irrigation source, and the processor determines which identifier is associated with the image.