Abstract: A pipe for fluid supply includes: a pipe configured integrally with an air feeding conduit and a pressure measurement conduit; inlets of the air feeding conduit and the pressure measurement conduit; outlets of the air feeding conduit and the pressure measurement conduit; and tube connection portions provided at the respective inlets in the pipe such that an angle between a vertical direction of the respective inlets and a vertical direction of each the respective outlets is 30° to 60°.

Abstract: A dispensing device to deliver a multiple component material to a location in vivo. The device includes a manifold having proximal and distal ends and multiple separate lumens within it, connectable on its proximal end to multiple syringes for containing the multiple component material, a distal tip assembly comprising a tip connector having separate side-by-side lumens within the tip connector and optionally a dispensing tip, and multiple flexible side-by-side cannulae. Each cannulae has a proximal end and a distal end, the proximal ends of the cannulae are connected to a separate lumen at the distal end of the manifold, and the distal ends of the cannulae are connected to one of the side-by-side lumens of the tip connector, establishing a fluid communication between the manifold and the distal tip assembly, wherein the side-by-side cannulae are optionally partially connected along their length and are split at their proximal and distal ends.

Abstract: Devices and methods are provided for sealing a catheter insertion site to maintain sterility. In one aspect of the invention, mounting handle/dressing assemblies and kits are disclosed for creating a sterile sealed environment around a catheter insertion site. For example, the dressings of the present invention can be pre-disposed around a mounting handle and connector. The connector is joined to the proximal end of the catheter and then the dressing can be slid along the mounting handle until it surrounds the insertion site. Once the dressing is adhesively applied to the skin and locked into place by an annular fitting between the dressing and the connector, the handle can be removed and discarded, leaving only the dressing, and catheter connector in place. The catheter connector preferably has a needle-free connector port at its proximal end for connection to IV lines or other infusion devices.

Abstract: A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification.

Abstract: An apparatus for treating a tissue site comprising a negative-pressure source configured to be fluidly coupled to the tissue site; an instillation source configured to be fluidly coupled to the tissue site; and a controller operatively coupled to the negative-pressure source and to the instillation source. The controller can be configured to operate the negative-pressure source and the instillation source to intermittently deliver negative pressure to the tissue site for a negative-pressure interval and deliver instillation fluid to the tissue site for an instillation interval. A purge volume of instillation fluid may be delivered to the tissue site at a purge frequency. In some examples, the purge volume may be delivered through the second fluid conductor and removed through the first fluid conductor during a negative-pressure interval.

Abstract: A phacoemulsification or aspiration tip is designed for use in cataract surgeries. The phacoemulsification tip (also referred to as a phaco tip) can reduce the duration and energy of cataract surgeries because the phaco tip is designed to reduce the likelihood that cataract fragments will become clogged inside the phaco tip. For example, the phaco tip has a lumen with variable sized diameters, which helps filter out larger cataract fragments that are more likely to clog the phaco tip. Further, the phaco tip can have a larger diameter at a bend to prevent blockages. The opening of the phaco tip can have a sharp edge to shear cataract fragments into smaller pieces that are less likely to clog the phaco tip. By preventing blockages using the phaco tip and reducing the duration of cataract surgeries, patients may recover faster from the cataract surgeries.

Abstract: A method of labeling an intravenous (IV) system is disclosed. The method may begin with obtaining a label. A label may be formed of a polymeric material and include a top, a bottom, and an aperture formed in at least one of the top and the bottom. At least one of the top and the bottom may have an exterior surface. The label may be applied to an IV system by closing the top with respect to the bottom such that at least one of tubing or a port of the IV system is secured within the aperture. A medical professional may then write on the exterior surface of the label a name of a medication to be administered through the IV system.

Abstract: Devices and methods are configured to allow transcarotid or subclavian access via the common carotid artery to the native aortic valve, and implantation of a prosthetic aortic valve into the heart. The devices and methods also provide means for embolic protection during such an endovascular aortic valve implantation procedure.

Abstract: A method and apparatus for performing a surgical procedure is provided. The surgical procedure may be a phacoemulsification procedure but other procedures may employ the techniques disclosed. The design includes sensing, within the surgical site, for a material change in fluid flow relative to a predetermined threshold. Upon sensing the fluid flow materially differs from the predetermined threshold, the design temporarily increases aspiration vacuum pressure to the surgical site above a predetermined upper threshold toward a maximum vacuum level. The design applies electrically generated disruptive energy, including but not limited to laser and/or relatively low power ultrasonic energy, to the surgical site from a first point in time measured from when aspiration vacuum pressure is above the predetermined upper threshold to a second point in time where pressure falls below a predetermined lower threshold.

Abstract: A fluid ejection device includes a fluid chamber, a volume varying unit, a fluid supplying unit, and an ejection pipe. The volume varying unit generates pulsation in the pressure of a fluid in the fluid chamber. The fluid supplying unit supplies the fluid to the fluid chamber through a first channel. The ejection pipe receives the supply of the fluid, in which the pulsation is generated, from the fluid chamber through a second channel and ejects the supplied fluid from an ejection port. In a connecting part to the fluid chamber, the cross-sectional area of the second channel is five times or more as large as the cross-sectional area of the first channel. In the connecting part to the fluid chamber, the first channel and the second channel are arranged to be opposed to each other via the vicinity of the center of the fluid chamber.

Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.

Abstract: An apparatus for transferring an ovum from a follicle with a double lumen needle having at the distal needle end an aspiration lumen for removing an ovum from a follicle and a flushing lumen, the double lumen needle including an outer tube with an internally located inner tube that extends over at least part of the length of the outer tube, one of the lumens being bounded by the inner surface of the inner tube and the other of the two lumens by the space between the outer surface of the inner tube and the inner surface of the outer tube, and a connector having an outlet at a second connector end for discharging the flushing fluid with possibly an ovum to the exterior and having a channel that connects the outlet with the aspiration lumen and a flushing inlet for supplying the flushing fluid, such that the two fluid pathways within the connector and the double lumen needle are separated from each other, and the inner tube comprises a deformable material.

Abstract: A cannula has a body with a proximal end and a distal end and a tip on the distal end. The tip has an outer wall defining a lumen opening at the end of the tip and extending to the proximal end of the cannula. The tip further comprises one or more ribs extending into the lumen to support the outer wall from kinking when the cannula is flexed. The outer wall has a inner surface defining the lumen and a plurality of non-circular apertures formed in the tip extending into the lumen. The apertures having a major axis and a minor axis. The major axis aligned in relation to a circumference of the outer wall to prevent puckering or buckling when the tip is bent. This alignment is also designed to support the outer wall from kinking when the tip is bent.

Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.

Abstract: A venous cannula is disclosed having an insertion hole near the distal end and a leading end hole at the distal end. The cannula further includes a removable sleeve that is fitted within the insertion hole and preferably extends at least from the insertion hole to the leading end hole. In a preferred embodiment, the cannula also includes an introducer that fits within the removable sleeve and extends at least the length of the removable sleeve. The removable sleeve and introducer are designed to facilitate use of the Seldinger technique with the venous cannula. Additionally, a method for use of the Seldinger technique with the cannula is disclosed.

Abstract: A hand piece having an irrigation portion and an aspiration portion that are releasably coupled is disclosed. In an assembled configuration, the irrigation portion and the aspiration portion are coupled such that the hand piece may be manipulable by a user as a single unit. In a separated configuration, the irrigation portion and the aspiration portion may be utilized separate from each other. The irrigation portion and the aspiration portion may be freely moved between the assembled configuration and the separated configuration.

Abstract: Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.

Abstract: A regional anesthesia catheter used with a guide such as for example a needle cannula has a distal portion integrally connected to a main portion of the catheter by a junction portion that has a cross-sectional profile different from the distal and main portions, so as to predispose the distal portion of the catheter to move in a given direction when the distal portion is not guided by or constrained by the needle cannula. The cross-sectional profile of the junction portion may be configured in a particular shape, or be constructed to have a flexibility that predisposes the distal portion to bend, curve or move toward a given direction.

Abstract: A treatment instrument for endoscope of the present invention includes a puncture needle having a barb. A lymph node removing method of the present invention includes: an insertion step, wherein an endoscope has an insertable insertion portion which is inserted into an esophagus or a trachea being a lumen inside the body of a subject; the step of inserting a distal end portion arranged at the tip of the insertion portion of the endoscope into the lumen; a confirmation step of confirming the position of a mediastinal lymph node by performing ultrasound scanning using an ultrasound transducer arranged at the distal end portion; an anchoring step of placing an anchoring device which has been inserted through a channel inside the insertion portion of the endoscope, on the mediastinal lymph node by performing the ultrasound scanning; a incision step of cutting a wall of the lumen to make a fistula; and a drawing-in step of drawing the mediastinal lymph node into the lumen with the anchoring device.

Abstract: An indwelling needle assembly includes a stylet having a sharp needlepoint at an end thereof, a stylet hub secured to a base end of the stylet, a hollow outer needle in which the stylet is inserted, an outer needle hub secured to a base end of the outer needle, an opening formed at the base end or at a side of the outer needle hub to communicate with the inner cavity of the outer needle, a seal fitted onto the outer needle hub and in which a hole or slit is provided for insertion of the stylet therein, the hole or slit being formed to become closed when the inserted stylet is extracted, an operating part installed on the outer needle hub to move the stylet and outer needle along the longitudinal direction when the stylet is inserted into the outer needle, and a movement suppresser for stopping or suppressing moving the stylet relative to the seal when the operating part is operated.

Abstract: A triple lumen catheter comprises a transfusion lumen (4), a blood feeding lumen (2) and a blood removing lumen (3). The transfusion lumen (4) has a distal end and a leading end portion (12, 12A), the leading end portion progressively reducing in diameter to a proximal end. A transfusion port (4a) is formed in the proximal end of the transfusion lumen. The blood feeding lumen (2) has a blood feeding port (2a) in a region of the proximal end of the leading end portion, the blood feeding port opening at least partially in an axial direction of the leading end portion. The blood removing lumen (3) includes a pair of blood removing ports (3a, 3b) provided in opposite side walls of the catheter, the blood removing lumen extending from a distal end at least to the blood removing ports.

Abstract: A reduced pressure delivery system for applying a reduced pressure to a tissue site includes a manifold delivery tube having at least two lumens and a manifold having a plurality of flow channels. The manifold is disposed within a first of the lumens of the manifold delivery tube. A balloon having an inner space and being capable of assuming collapsed and expanded positions is provided. The inner space of the balloon is fluidly connected to a second of the lumens of the manifold delivery tube.

Abstract: The present disclosure describes a surgical access apparatus including an access member with a longitudinal opening defining an internal dimension suitable for removable receipt of a surgical instrument. The access member has a thread mounted thereon that is movable between a first condition and a second condition. When the thread is in the first condition, the access member defines a first outer dimension that allows for positioning of the access member within a tissue tract, and when the thread is in the second condition, the access member defines a second, larger outer dimension to facilitate anchoring of the access member within the tissue tract. As the thread moves between the first and second conditions, the internal dimension of the longitudinal opening extending through the access member remains substantially constant.

Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.

Abstract: An apparatus for transferring an ovum from a follicle with a double lumen needle having at the distal needle end an aspiration lumen for removing an ovum from a follicle and a flushing lumen, the double lumen needle comprising an outer tube with an internally located inner tube that extends over at least part of the length of the outer tube, one of the lumens being bounded by the inner surface of the inner tube and the other of the two lumens by the space between the outer surface of the inner tube and the inner surface of the outer tube, and a connector having an outlet at a second connector end for discharging the flushing fluid with possibly an ovum to the exterior and having a channel means that connects the outlet with the aspiration lumen and a flushing inlet for supplying the flushing fluid, wherein the two fluid pathways within the connector and the double lumen needle are separated from each other, and the inner tube comprises a deformable material.

Abstract: An apparatus for the injection of therapeutic and other agents at a target site within a patient's body. A catheter including a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also including a second elongated shaft slidingly disposed in the first elongated shaft, the second elongated shaft having a distal end and a proximal and a lumen extending therebetween. The catheter further including a third elongated shaft disposed in and attached to the second elongate shaft, the third elongated shaft to move in a one-to-one relationship with the first elongated shaft and the second elongated shaft to maintain a predetermined needle deployment length as each are subjected to various bend configurations.

Abstract: A luminal coupling tube system for providing access to a lumen of a subject is disclosed. The system includes an internal magnet assembly, a snare assembly, an external magnet, a pull wire system and a feeding tube assembly. The internal magnet assembly includes an internal magnet having a first coupling surface and a tether for traversing an endoscope instrument channel. The snare assembly includes a snare, a snare operating device, and a cable. The external magnet includes a second coupling surface. The polar orientation of the external magnet is opposite the polar orientation of the internal magnet such that the first and second coupling surface are magnetically attracted. The pull wire system includes a needle, a cannula and a pull wire. The feeding tube assembly includes a tube, a snare, a connector, and a dome fixed to the tube. A method of use is disclosed.

Abstract: A needle device which is manufactured from shape memory or pseudo-elastic materials, such as Nickel Titanium alloys, is provided which may be formed and used repeatedly without adverse effects, such as permanent deformation or fatigue failure. The device in accordance with the present disclosure may be provided having an initial shape which a doctor may bend to a desired shape. The device may be easily returned to its initial shape after use by heating the device above a predetermined sterilization temperature. This cycle may be repeated during subsequent uses, substantially extending the life of the instrument, due to the reduced work hardening and enhanced fatigue properties of the Nickel Titanium device.

Abstract: A micro perfusion device including a casing, a perfusate supply, an inner cannula forming an inner lumen between a front cannula opening which is distal when the device is subcutaneously positioned and a rear cannula opening, the inner lumen being connected or connectable to the perfusate supply via the rear cannula opening, a perfusion cannula projecting from a lower side of the casing and surrounding the inner cannula, an outer lumen between the inner cannula and the perfusion cannula, a collecting container for the perfusate, and a perfusate outlet connecting the outer lumen to the collecting container, wherein the collecting container has a variable volume and a partial vacuum with respect to a pressure prevailing in the perfusate supply may be generated in the collecting container.

Abstract: A medical system for connecting a multiple lumen medical catheter to associated medical instrumentation includes a connector member defining a longitudinal axis and having a first end for releasable coupling to the medical catheter and a second end for coupling to medical instrumentation. A mounting segment is adjacent the first end of the connector member. The mounting segment includes first and second mounting elements extending in a general longitudinal direction and arranged in spaced relation, and being adapted for reception within respective lumens of the catheter. The first and second mounting elements define inner opposing surfaces. At least one of the opposing surfaces may have an irregular surface portion dimensioned to engage the septum wall of the catheter to facilitate gripping engagement with the septum wall to assist in coupling of the connector member with the catheter.

Abstract: Blood collecting devices for collecting blood from a patient using a single needle insertion are disclosed. Each blood collecting device typically includes a housing which is removably attached to a test tube or blood reservoir. A blood flow tube is disposed in fluid communication with the housing for distributing blood from a patient into the test tube or blood reservoir. The blood is distributed through a membrane cavity having a liquid-impervious and air-permeable membrane. At least one air opening is provided in the housing at the membrane cavity. Accordingly, air in the test tube or blood reservoir is displaced by the incoming blood through the membrane cavity and membrane and out the air opening or openings. Vacuum pressure in the test tube or blood reservoir is dispelled by the flow of air through the air opening or openings, membrane cavity and membrane and into the test tube or blood reservoir, respectively.

Abstract: A chest compressor includes a piston (14) that moves in downward and upward strokes, with the piston undergoing a smooth reversal at the bottom of the downward stroke. A compression spring such as a wave spring (60), is positioned to engage the piston only near the end of its downward stroke, to smoothly reverse the piston motion, limit downward force on the patient at the end of the stroke, and avoid a downward pulse due to the momentum of the downwardly-moving piston. A stop (90, 92) is latchable in an inward position to allow reduction in the piston stroke by engaging an outward flange (56) on the piston before the piston has moved fully downward.

Abstract: A microdialysis probe with a probe body, a probe needle for introduction into a tissue, an inlet line and an outlet line for a perfusion solution and a dialysis membrane, wherein at least one hollow channel forms the outlet line and extends at least partly spirally about the probe needle on an external surface of the probe needle. The inlet for the perfusion solution may also be in the form of spiral about the external surface of the probe needle.

Abstract: A catheter adapter apparatus includes an adapter body. The adapter body includes a fluid source end adapted for connection to a fluid source and having an internal bore to transfer the fluids supplied by the fluid source, and a catheter end for connection to a catheter tube. The catheter end includes first and second members. Each of the first and second members is adapted for reception within corresponding lumens of the catheter tube. At least the first member defines an internal bore in fluid communication with the fluid source end to transfer the fluids supplied by the fluid source. The second member may define an internal bore in fluid communication with the internal bore of the fluid source end. The catheter adapter apparatus may further include a valve member associated with the adapter body. The valve member may be movable to selectively fluidly connect the internal bores of the first and second members with the internal bore of the fluid source end.

Abstract: An instrument for facilitating insertion of a catheter through a subcutaneous tunnel includes a tunneling stylet defining a longitudinal axis and having leading and trailing ends, a bifurcated segment adjacent the leading end of the tunneling stylet and a releasable cover releasably mountable to the leading end of the tunneling stylet to substantially enclose the bifurcated segment. The bifurcated segment includes first and second elements adapted for reception within respective lumens of a catheter. The instrument may further include a dilation member which is releasably mountable to the leading end of the tunneling stylet in the absence of the releasable cover. The dilation member is dimensioned to generally increase an internal dimension of the subcutaneous tunnel. The first and second elements of the bifurcated segment each include an outer peripheral rib dimensioned to facilitate gripping engagement with an internal surface of respective lumens of the catheter.

Abstract: Method for draining and decompressing a colon in which a drainage tube is inserted through the anus into the colon to extend through the entire colon. The drainage tube is fixed in position and suction is applied therethrough to cause fecal matter to pass therein through apertures and be withdrawn from the colon. The drainage tube is inserted by inserting a guidewire into the colon through the anus, manipulating and pushing the guidewire to the cecum, passing a filament through the colon wall to engage the guidewire, pulling the guidewire out of the colon and anus to draw the filament through the colon and out of the anus, attaching the drainage tube to the filament and drawing the filament with attached drainage tube through the anus into the colon. The invention also relates to constructions of the guidewire, the drainage tube and methods for inserting drainage tubes using guidewires.

Abstract: A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include applying energy during at least one pulsed energy on period, typically sufficient or intended to rapidly induce and beneficially employ transient cavitation. Applying energy during the pulsed energy on period comprises applying energy during a first high energy period, and applying energy during a second nonzero lower energy period.

Abstract: The surface of a needle for collecting samples is coated with a coating material lower in chemical activity than a base metal of the needle. More specifically, the surface of the needle may be coated with a layer of gold or platinum. Alternatively, the surface of the needle may be coated with a synthetic resin coating of, for example, PEEK which is superior in chemical resistance. As a result, it is possible to obtain a practically sufficient antifouling effect even on contamination coming from chemical adsorption. Such contamination could not be removed sufficiently only by related-art measures against physical contamination. Thus, it is possible to provide an automatic sampler which can perform highly sensitive analysis.

Abstract: A micro perfusion device including a casing, a perfusate supply, an inner cannula forming an inner lumen between a front cannula opening which is distal when the device is subcutaneously positioned and a rear cannula opening, the inner lumen being connected or connectable to the perfusate supply via the rear cannula opening, a perfusion cannula projecting from a lower side of the casing and surrounding the inner cannula, an outer lumen between the inner cannula and the perfusion cannula, a collecting container for the perfusate, and a perfusate outlet connecting the outer lumen to the collecting container, wherein the collecting container has a variable volume and a partial vacuum with respect to a pressure prevailing in the perfusate supply may be generated in the collecting container.

Abstract: A method and apparatus for delivering energy during a surgical procedure such as phacoemulsification is provided. The method and apparatus include applying energy during at least one pulsed energy on period, comprising applying energy during a series of short burst periods, the short burst periods interspersed by short rest periods. The method and apparatus further comprise delivering minimal energy during a long off period, the long off period comprising a relatively long period when minimal energy is applied, wherein one long off period follows each pulsed energy on period. The short burst periods and the short rest periods are relatively brief in duration as compared with the long off period.

Abstract: Improved automatic chest compression systems which use constricting belts, repeatedly inflating bladders, or reciprocating pistons to compress the chest. A bladder is placed between the chest and the particular mechanism used to compress the chest during CPR. The bladder maximizes the effectiveness of chest compressions.

Abstract: A needle device which is manufactured from shape memory or pseudo-elastic materials, such as Nickel Titanium alloys, is provided which may be formed and used repeatedly without adverse effects, such as permanent deformation or fatigue failure. The device in accordance with the present disclosure may be provided having an initial shape which a doctor may bend to a desired shape. The device may be easily returned to its initial shape after use by heating the device above a predetermined sterilization temperature. This cycle may be repeated during subsequent uses, substantially extending the life of the instrument, due to the reduced work hardening and enhanced fatigue properties of the Nickel Titanium device.

Abstract: An agent delivery device includes an outer tubular body having a distal end, a proximal end, and a lumen extending between the distal end and the proximal end, an inner tubular body positioned coaxially within the lumen of the outer tubular body, the inner tubular body having a distal end configured for puncturing tissue, a proximal end, and a lumen extending between the distal end and the proximal end of the inner tubular body, and a suction port located at the distal end of the outer tubular body, the suction port being in fluid communication with the lumen of the outer tubular body. The inner tubular body may be fixedly or slidably secured to the outer tubular body. The agent delivery device may further include a monopolar or bipolar electrode and/or a radio-opaque marker carried at the distal end of the device.

Abstract: Injection devices are provided, which reduce potential outflow of therapeutic agents from an injection site. Devices are provided having at least a first lumen containing one or more therapeutic agents and a second lumen containing a second material for injection into tissue. Other devices are provided having an inner lumen with an injection needle to inject a therapeutic agent and an outer lumen that provides a vacuum seal between the injection needle and the needle track. Further provided are methods of delivering a therapeutic agent to tissue.

Abstract: The multilumen catheter (2) is provided at one end with a needle system (9, 9′) formed by two or more single-lumen needles which are provided with respective discharge openings (110, 111) and which, via their longitudinal lumina (10, 11), are connected to corresponding lumina (3, 4) of the catheter for separate release of a tracer fluid for external image diagnostics systems and therapeutic fluids, for example DNA plasmids. The needles may be both straight or both helical or one of these needles may be straight and the other needle may be helical.

Abstract: A micro perfusion device and method for obtaining at least one constituent of a body fluid. The at least one constituent is obtained using a subcutaneously-positioned perfusion catheter into which perfusate is introduced by a supply channel and an injection needle. The perfusate absorbs the at least one constituent as it flows out of the perfusion catheter and through a discharge channel.

Abstract: Sleeve apparatus for a phacoemulsification/irrigation and aspiration handpiece includes an elongate sleeve having a proximal and a distal end with a sleeve establishing an annular passage around a needle enabling irrigation fluid to pass into the eye through the passage and into the eye while cooling the needle. The elongate sleeve includes a hub disposed a proximal end for enabling attachment of the sleeve to the handpiece and a port disposed approximate the distal end and in fluid communication with the annular passage is provided for introducing irrigation fluid into the eye. An Internal circumferential berm, disposed between the port and the distal end is provided to reduce flow of the irrigation fluid therepast, to provide rigidity to the distal end of the sleeve and concomitantly provide limited contact with the needle in order to produce thermal transfer therebetween.

Abstract: A multi-lumen catheter and method of manufacturing such a multi-lumen catheter having a plurality of individual catheter tubes. Each catheter tube has an outer surface, an inner surface and a lumen. The catheter tubes can be made of different thermoplastic materials. A mandrel is first inserted into the lumen of each catheter tube to provide support. The catheter tubes are then juxtaposed to each other in an arrangement. Importantly, the outer surface of one catheter tube is in contact with the outer surface of at least one other catheter tube in the arrangement. The arrangement of catheter tubes is then held in a sleeve and is advanced through the sleeve, and through a heating cylinder to fuse the outer surfaces of the catheter tubes. A cooling means is placed in the lumen of each catheter tube to prevent the inner surface of each catheter tube from melting.

Abstract: The invention relates to a micro-dialysis probe which includes a supply line (1) and a drainage line (6) for a drip-feed solution and a dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion in the area of the dialysis section between the supply line (1) and the drainage line (6), and wherein both the supply line (1) and the drainage line (6) are respectively arranged as separate hollow channels on the outer wall of the probe, side by side, in particular parallel.

Abstract: An automatic injection device has piston holders holding cylinder pistons and plural systems of heads having a drive mechanism for moving the piston holders forward and backward so that the device can hold a plurality of syringes and operates injection or suction in each syringe independently. This device also has a mechanism for prohibiting the backward-moving of the piston holder of a second head when the piston holder of a first head is in a forward-moving state and the piston holder of the second head is in a stopped state. This structure effectively prevents liquid from being undesirably mixed and the injection amount thereof from becoming less accurate.