Pumping Means Patents (Class 604/6.11)
  • Publication number: 20100262063
    Abstract: A switch comprises a rotating switch member which provides fluid communication in three modes; infusion, recirculation and priming The switch is located between the oxygenator and drug bag and the cardioplegia pump raceway. The switch has three channels molded into the rotating manifold which either direct blood and cardioplegia into the coronary arteries of the patient or into a recirculation line. When the switch is rotated into the recirculation line, a hose is in fluid connection through the switch and connects the recirculation line with the pump blood and drug inlet lines thereby allowing cooling of the cardioplegic mixture during the time between infusions.
    Type: Application
    Filed: April 9, 2009
    Publication date: October 14, 2010
    Inventor: William G. O'Neill
  • Patent number: 7794419
    Abstract: The apparatus for blood flow control in an extracorporeal circuit comprises: a user interface for setting a desired blood flow value (qbREAL) and a datum relating to the vascular access, a memory for recording a plurality of mathematical relations having mathematical expressions relating to the vascular access organ to be used, and a control unit. The control unit identifies the vascular access, selects, from among the plurality of mathematical relations present in the memory, a relation which corresponds to the vascular access identified, and calculates, as a mathematical function of the set value for the desired flow (qbREAL), a value at which to set the angular velocity of the pump associated to the extracorporeal circuit and/or a theoretical value of the arterial pressure upstream of the pump.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: September 14, 2010
    Assignee: Gambro Lundia AB
    Inventors: Francesco Paolini, Carlo Alberto Lodi, Francesco Fontanazzi
  • Patent number: 7789847
    Abstract: A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures involve filtering the separated red blood cells in a diluted state after and/or prior to flushing the filter with storage solution. Storage solution may thus be passed through the leukoreduction filter before, with and/or after the RBCs have been filtered therethrough. The red blood cell collection, filtration and storage assembly is preferably preconnected to a blood component separation disposable assembly, including, for example, a centrifuge vessel and a blood removal/return assembly for removing blood from a donor, passing the blood to the centrifuge vessel for separation of the blood into components for collection and providing for filtration of the separated red blood cell component.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: September 7, 2010
    Assignee: CaridianBCT, Inc.
    Inventors: Bruce W. Gibbs, Jon Herskovits
  • Patent number: 7785284
    Abstract: The joint (36) comprises a tubular body (37) having two connecting zones (38, 39) each connected by an end to a tubular element (40) of a fluid transport line, giving continuity to passage of fluid. The tubular body is made of a mixture of an electrically-conductive material such as PVC, with carbon black to give it electrical conductivity. The joint has an internal surface (41) which is destined to come into contact with the transported fluid, and an external surface which is destined to have a grounded galvanic contact. The joint is inserted in the discharge fluid drainage line of a dialyzer filter, in an apparatus for intensive treatment of acute renal insufficiency, for eliminating ECG artefacts due to functioning of peristaltic pumps in the apparatus.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: August 31, 2010
    Assignee: Gambro Lundia AB
    Inventors: Vincenzo Baraldi, Annalisa Delnevo, Gianfranco Marchesi, Andrea Ligabue, Massimo Zaccarelli
  • Patent number: 7785463
    Abstract: A system, program product and method continuously optimize an ultrafiltration rate during an extracorporeal renal replacement process by modeling physiological and actual rate data. The system maps the sensed, physiological data to a mathematical model to assess the data in terms of the ultrafiltration rate. The model provides parameters used to predict where the treatment is headed based on current conditions. The system processes the parameters in terms of preset criteria to generate the optimized ultrafiltration rate. Where the system is networked, communication of the data may be accomplished using remote and online communication techniques.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: August 31, 2010
    Assignee: Children's Hospital Medical Center
    Inventors: John J. Bissler, Nat Hemasilpin, Marios M. Polycarpou
  • Patent number: 7788038
    Abstract: The invention comprises a patient information server device which automatically accumulates together with time information: biological information detected by a bedside monitoring device of a patient or a biological-measuring device; biological information and device information detected by a blood purification device which treats a blood sample taken from the patient; and blood information detected by a circulating blood volume measuring device that detects blood information about a circulating blood sample taken from the patient. A client device simultaneously and chronologically displays or records the patient information stored in the patient information server device. Through this arrangement, it is possible to obtain on a real time basis the biological information of a human body such as a patient's body, and the device information, for example, of a blood treating device.
    Type: Grant
    Filed: December 27, 2001
    Date of Patent: August 31, 2010
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Shuzo Oshita, Yasuhiro Kuroda, Toshiya Okahisa, Yoshiaki Ohnishi, Noriko Okumura
  • Patent number: 7780848
    Abstract: A single needle hemodiafiltration apparatus is provided. The single needle hemodiafiltration apparatus includes circuits for blood supply from a patient and blood return to a patient, a dialysis fluid supply system for supplying a dialysis fluid, and a system for controlling the blood flow and dialysis fluid flow in a separation device which is equipped to perform filtration and back-filtration operations. A controller is provided that controls, in a series of coordinated operations, the flow of blood from the patient into the separation device, the flow of filtration fluid and back filtration fluid, and the return of blood to the patient.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 24, 2010
    Assignee: JMS Co.
    Inventors: Sung-Teh Kim, Kunihiko Yamanaka, Naritomi Maeda, Katsunori Masaoka, Kayoko Segawa, Chieko Yamamoto
  • Patent number: 7780620
    Abstract: A method for determining the hematocrit and/or blood volume during an extracorporeal blood treatment with an extracorporeal blood circuit, in which blood is taken with a blood pump via an arterial cannula and an arterial flexible-tube line and blood is fed back via a venous flexible-tube line and a venous cannula. Pressure is measured in the extracorporeal blood circuit and a change in the hematocrit is determined from a change in the pressure. The respective relationship between hematocrit HKT or blood volume RBV and pressure P in the extracorporeal circuit is stored for various cannula diameters and various blood-flow values. The respective relationship for a given cannula diameter and blood flow is selected. The hematocrit and/or blood volume is determined taking account of the selected relationship.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: August 24, 2010
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Wei Zhang, Helge Brauer, Reiner Spickermann, Carsten Müller
  • Patent number: 7780621
    Abstract: A blood chamber for an extracorporeal blood circuit comprises a blood inlet port (2), a blood containment chamber (3), a first conduit (8) which connects the blood inlet port (2) with the blood containment chamber (3) and which has an end tract (8a) that terminates in the blood containment chamber (3) with a horizontal inlet component. The first conduit (8) comprises a pre-terminal tract (8b) which precedes the end tract (8a) and which has at least a second horizontal component which is directed in an opposite direction to the horizontal inlet component. The blood chamber is used in an arterial line of a dialysis set for guaranteeing a regular and gentle blood flow.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: August 24, 2010
    Assignee: Gambro Lundia AB
    Inventors: Robert Neri, Andrea Paltrinieri
  • Publication number: 20100204634
    Abstract: Devices, methods, and assemblies for perfusion therapy including cerebral perfusion therapy such as those for use in the treatment of acute ischemic stroke. The treatment includes delivery of blood to or about the vicinity of a thrombus site.
    Type: Application
    Filed: February 8, 2010
    Publication date: August 12, 2010
    Inventors: Blaise Baxter, Thomas Devlin, Christian Devlin
  • Publication number: 20100198132
    Abstract: A blood treatment method is described that is adapted to at least partially eliminate the carbon dioxide content of the type comprising a step of drawing a blood flow. Advantageously according to the invention, the method further comprises the steps of: acidifying the blood flow with transformation of the related blood bicarbonate content into gaseous carbon dioxide; and eliminating the gaseous carbon dioxide content by means of a pressure gradient.
    Type: Application
    Filed: May 7, 2008
    Publication date: August 5, 2010
    Applicant: UNIVERSITÁ DEGLI STUDI DI MILANO-BICOCCA
    Inventor: Antonio Maria Pesenti
  • Patent number: 7766853
    Abstract: A cannulation system (10) for perfusing a patient's circulatory system, includes an inflow cannula (14) having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump (19), an outflow cannula (23) having a first end adapted to be connected to the blood pump (19) and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump (19) is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: August 3, 2010
    Assignee: Droneon Pty Limited
    Inventor: Rodney James Lane
  • Patent number: 7758533
    Abstract: A hemofiltration system and method to treat an Inflammatory Mediator Related Disease in a mammal, including chronic and acute diseases, include a hemofilter and an adsorptive device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorptive device may include one or more adsorbent materials and may be used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream may be selectively combined with the filtered blood stream and together with the filtered blood stream may be returned to the mammal.
    Type: Grant
    Filed: November 5, 2007
    Date of Patent: July 20, 2010
    Assignee: Immunocept, L.L.C.
    Inventor: James R. Matson
  • Patent number: 7758547
    Abstract: A process comprises the phases of: activating a pusher, which exerts a push force on a plunger of a syringe containing the infusion liquid; measuring the push force by means of a load cell; comparing the push force with a maximum threshold; halting the pusher when the maximum threshold is exceeded; after a predetermined pause, restarting the pusher and emitting a consent signal indicating correct loading of the syringe if, within a certain time from the restart, the push force again exceeds the maximum threshold. The infusion device serves to inject an anticoagulant into an extracorporeal blood circuit. The control process guarantees against loss of infusion due to an incorrect initial loading of the syringe.
    Type: Grant
    Filed: April 13, 2005
    Date of Patent: July 20, 2010
    Assignee: Gambro Lundia AB
    Inventors: Claudio Tonelli, Andrea Ligabue, Silvano Cestari
  • Publication number: 20100175483
    Abstract: A system is disclosed for detecting an electrical sensor, the system includes a sensor signal processing circuit further comprising an input port to receive a connector including the output signal lines of the sensor, a resistor connected to the output signal line of said input port, wherein the resistor is connected to a predetermined voltage; a sensor circuit having a connector adapted to connect to the connector, wherein the sensor circuit has a resistance substantially less than the pull-resistor, and the sensor signal processing circuit detects an unconnected sensor based on the voltage applied by the resistor.
    Type: Application
    Filed: January 15, 2010
    Publication date: July 15, 2010
    Applicant: CHF SOLUTIONS INC.
    Inventors: John J. O'Mahony, Mark Gelfand, Edwin B. Merrick, Jayne B. Merrick
  • Patent number: 7749435
    Abstract: An oxygenator which helps avoid bubbles in the blood from being discharged through the blood outlet port of the oxygenator includes a housing, a hollow fiber membrane bundle in the housing and formed by a multiplicity of hollow fiber membranes serving for gas exchange, gas-inlet and gas-outlet ports communicating with gas passages of the hollow fiber membranes, and a blood-inlet and blood-outlet ports. A filter member is provided on a side closer to the blood outlet port of the hollow fiber membrane bundle and serves to catch bubbles in blood. The blood outlet port projects from the housing and a passage enlargement is provided in a vicinity of the end of the blood outlet port closer to the housing and having an increased passage cross-sectional area. The blood passed the filter member is allowed to reach the blood outlet port by being decelerated in the passage enlargement.
    Type: Grant
    Filed: January 19, 2007
    Date of Patent: July 6, 2010
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Mitsuaki Ogihara, Hidetaka Nakayama, Kazuhiro Mizoguchi
  • Patent number: 7749184
    Abstract: In the apparatus and method for monitoring a vascular access (6) of an extracorporeal circuit (5; 10) of a patient, a control and calculation unit (17) varies a flow rate of a blood pump (9) predisposed to cause blood to circulate in the extracorporeal circuit. The control and calculation unit receives the pressure values in the blood withdrawal line (5) and the blood return line (10) from two pressure sensors (8, 12); the pressure values are a series of different values of the blood flow rate. The control and calculation unit processes the data gathered by means of a mathematical model which describes the variation of pressure in the vascular access as a function of the flow rate, in order to determine the blood flow rate in the vascular access. The invention detects the presence and location of a stenosis at the vascular access of a patient subjected to a hemodialysis treatment.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: July 6, 2010
    Assignee: Gambro Lundia AB
    Inventors: Silvio Cavalcanti, Carlo Alberto Lodi, Massimo Fava
  • Publication number: 20100168641
    Abstract: A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator.
    Type: Application
    Filed: March 8, 2010
    Publication date: July 1, 2010
    Applicant: CHF SOLUTIONS INC.
    Inventors: John J. O'Mahony, Mark Gelfand, Edward G. Rychlick
  • Publication number: 20100168925
    Abstract: The present invention relates to a device and a method for controlling an extracorporeal blood treatment device, in particular a hemodialysis device that has a dialyzer, which is divided by a semi-permeable membrane into a blood chamber and a dialysis chamber, a blood pump for conveying blood through the blood chamber at a defined blood flowrate Qb, and a dialysis pump for conveying dialysis fluid through the dialysis chamber at a defined dialysis flowrate Qd. The control device and method according to the present invention for a hemodialysis device are based on the fact that, for different blood flow rates, in each case pre-defined during the blood treatment, the dialysis flowrates are determined at which a pre-defined clearance or dialysance is maintained with the pre-defined blood flowrates and/or that, for different dialysis flowrates in each case pre-defined during the blood treatment, the blood flowrates are determined at which the predefined clearance of dialysance is maintained.
    Type: Application
    Filed: June 6, 2007
    Publication date: July 1, 2010
    Inventors: Peter Hilgers, Jorg Jonas
  • Patent number: 7744553
    Abstract: Systems and methods for improving medical fluid delivery systems, such as hemofiltration (“HF”) and hemodiafiltration (“HDF”) are provided. In first embodiments, systems and methods for selectively performing pre- and postdilution HF and HDF clearance modes is provided. In other embodiments, systems and methods for providing prime bolus and rinseback fluid volumes before, during and/or after HF and HDF therapies are provided. In further embodiments, improved systems and methods for removing ultrafiltrate from the patient are provided. Still further, improved filtration configurations and methods are provided.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: June 29, 2010
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Thomas D. Kelly, Waleed M. El Sayyid
  • Patent number: 7744554
    Abstract: A method for aligning a disposable cassette within a dialysis machine includes actuating a pump head toward the disposable cassette and to contact a pumping portion of the disposable cassette and shift the disposable cassette if need be into proper operational alignment and locking the disposable cassette in place.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: June 29, 2010
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: David Howard
  • Patent number: 7731675
    Abstract: An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: June 8, 2010
    Assignee: Maquet Cardiovascular LLC
    Inventors: Walid N Aboul-Hosn, William R Kanz, Bruce A. Baker
  • Patent number: 7727176
    Abstract: The invention relates to support element (4) comprising a main body (6) having a front wall (25) and a peripheral wall (32) projecting away from the front wall. The front wall and the peripheral wall define a housing compartment (33) designed to receive a fluid distribution circuitry cooperating with a treatment unit for defining an integrated blood treatment module.
    Type: Grant
    Filed: June 6, 2007
    Date of Patent: June 1, 2010
    Assignee: Gambro Lundia AB
    Inventors: Claudio Tonelli, Vincenzo Baraldi, Massimo Zaccarelli, Annalisa Delnevo, Francesco Ribolzi, Jacques Chevallet, Jacques Duchamp, Aziz Aberkane, Gabriel Meyssonnier, Dominique Pouchoulin
  • Patent number: 7727391
    Abstract: The invention relates to an extracorporeal blood treatment machine in which a blood circuit (3) is equipped with an inlet line leading to a filtration unit (2) and with an outlet line (3b) from the filtration unit; a fluid circuit comprises an inlet line (4a) leading to the filtration unit and an outlet line (4b) from the filtration unit so as to allow a fluid taken from a primary container (5) to circulate within the filtration unit, thus enabling the treatment of the patient's blood. There is further an infusion line (6) acting on the outlet line of the blood circuit, which is supplied by an auxiliary fluid container (7). The inlet line of the fluid circuit is equipped with at least an infusion branch (8) acting on the outlet line of the blood circuit so as to enable the intensive therapy machine to manage therapies with large exchange of fluids.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: June 1, 2010
    Assignee: Gambro Lundia AB
    Inventors: Annalisa Delnevo, Francesco Ribolzi, Claudio Tonelli, Vincenzo Baraldi, Massimo Zaccarelli, Jacques Chevallet, Jacques Duchamp, Aziz Aberkane, Gabriel Meyssonnier, Dominique Pouchoulin
  • Publication number: 20100130906
    Abstract: The invention relates to the field of equipment for renal replacement therapy. It is based on the observation that connections (14, 15, 101) already present in a hemodialysis machine or hemodiafiltration machine (10) may also be used directly for sampling for the connection to a hemodialyzer or for providing replacement fluid, as is required for regular microbiological testing. The invention does not require any additional components on the equipment or any complex hygiene measures to prevent secondary contamination. By connecting an inventive sterile sampling set, samples can easily be taken. On the equipment end, one need only to program the control unit (26) to implement the inventive method by means of corresponding control of the closing means (20, 21, 103) and the pumping mechanisms (17, 18) as part of a sampling control program.
    Type: Application
    Filed: October 22, 2007
    Publication date: May 27, 2010
    Inventors: Klaus Balschat, Reiner Spickermann
  • Patent number: 7722557
    Abstract: A blood purification apparatus in which the pressure in a circuit is measured by directly measuring the strain of an air trap by a strain sensor without providing a pressure measuring section in the circuit.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: May 25, 2010
    Assignee: Nipro Corporation
    Inventors: Yoshihiko Sano, Makoto Mitsuhashi, Hidetoshi Saio
  • Publication number: 20100114002
    Abstract: A method for controlling the blood glucose level of a patient and periodically calibrating the glucose sensor using a calibration solution. The method controls the level of blood glucose in a patient through an extracorporeal blood circuit by: withdrawing blood from a vascular system in the patient to the extracorporeal circuit; removing ultrafiltrate from the withdrawn blood in the circuit; determining a level of glucose present in the blood based on the removed ultrafiltrate; infusing at least a portion of the removed ultrafiltrate and the withdrawn blood into the vascular system, and infusing insulin into the patient based on the determined level of glucose.
    Type: Application
    Filed: October 10, 2009
    Publication date: May 6, 2010
    Inventors: John J. O'Mahony, Donald W. Landry
  • Publication number: 20100114001
    Abstract: An extracorporeal blood processing method using a blood circuit comprising a pair of blood passages attached to opposite flow ends of a blood treatment device and said blood circuit is mounted on a blood pump console, the method includes: withdrawing blood from a vascular system of a human patient and drawing the blood into the blood circuit; pumping the withdrawn blood through one of the pair of blood passages using a first blood pump of the console and into the blood treatment device; pumping the treated blood from the treatment device through the other of the pair of blood passages using a second blood pump of the console; infusing the treated blood from the other blood passage and into the vascular system of the patient, and periodically reversing a flow direction of blood through the pair of blood passages and blood treatment device.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 6, 2010
    Applicant: CHF Solutions, Inc.
    Inventor: John J. O'Mahony
  • Patent number: 7704221
    Abstract: A rotary valve unit is provided for blending fluid sources to regulate a temperature of fluid flowing to a heat exchange device in an extracorporeal blood perfusion circuit. A valve body includes a valve chamber having a first inlet port, a second inlet port, a first outlet port, and a second outlet port. A wedged-shaped rotary valve is disposed within the valve chamber and is rotatable within the valve chamber for controlling a blending of the cold fluid entering the fluid chamber from the first inlet port and the return fluid entering the fluid chamber from the second inlet port to regulate the desired temperature of fluid provided to the heat exchanger. The wedge-shaped rotary valve is positionable to provide either only cold fluid to the first outlet port, only return fluid to the first outlet port, or blending of the cold fluid and return fluid to the first outlet port.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: April 27, 2010
    Assignee: Terumo Cardiovascular Systems, Corporation
    Inventors: Guy C. Mannlein, John M. Adams, David Danielson, Brian M. Boniface
  • Publication number: 20100094193
    Abstract: An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.
    Type: Application
    Filed: December 11, 2009
    Publication date: April 15, 2010
    Applicant: NATIONAL QUALITY CARE, INC.
    Inventors: VICTOR GURA, EDMOND RAMBOD
  • Publication number: 20100094194
    Abstract: In a blood therapy apparatus having a load cell sensor and a coupler for securing a load, a bag thereon is characterized by a free hanging link hanging from the coupler, and a bag hanger comprising an elongated rod having a plurality of bag engaging hooks and upwardly extending hook secured at the weight center of the rod and freely hanging from the links.
    Type: Application
    Filed: October 12, 2009
    Publication date: April 15, 2010
    Applicant: TRANSVIVO INC.
    Inventors: Harold Peters, Adam Heintzelman, Jacob Kearns, Tommy Cooper
  • Publication number: 20100087771
    Abstract: Provision of a blood purification system comprising a blood purification tubing and a blood purification apparatus particularly suitable for use in continuous hemofiltration in which in the treatment of a patient with renal disease, multiple organ failure, and the like, the amount of water removed from the patient and the amount of supply to the patient can be more accurately controlled, and in which preparation operation is easy. A blood purification system comprising a blood purification tubing and a blood purification apparatus wherein the soft tubes of flow paths connecting a first planar panel and a second planar panel, and the location of the soft tubes are selected to satisfy a formula of a predetermined condition.
    Type: Application
    Filed: February 14, 2008
    Publication date: April 8, 2010
    Applicant: ASAHI KASEI KURARAY MEDICAL CO., LTD.
    Inventors: Atsushi Karakama, Soichiro Okazaki
  • Publication number: 20100087772
    Abstract: The invention relates to a method for the emptying of a blood tubing set of a blood treatment device comprising an extracorporeal blood circuit including a membrane filter having a first chamber and a second chamber separated therefrom by a membrane, said first chamber being flowed through by blood in operation of the blood treatment device and said second chamber being flowed through by filtrate in operation of the blood treatment device, and said blood tubing set including an arterial blood tube and a venous blood tube which are both in communication with the first chamber of the membrane filter and which conduct blood from the patient to the membrane filter and from the membrane filter to the patient in operation of the blood treatment device, and comprising a substituate line which opens into the arterial blood tube and/or into the venous blood tube, and comprising a substituate pump which is in communication with the substituate line such that it conveys substituate from a substituate source through the
    Type: Application
    Filed: August 27, 2007
    Publication date: April 8, 2010
    Inventors: Soeren Gronau, Juergen Haecker, Goetz Guenther, Max Fischer, Joachim Noack
  • Patent number: 7686777
    Abstract: An in-vitro blood plasma lipids filtering method includes the following steps: separating out the blood plasma from the blood collection; flushing a filtering device with saline solution; controlling the pressure of the separated blood plasma; passing the blood plasma to the filtering device for filtering out lipids; controlling the temperature of the filtered blood plasma; and feeding the blood plasma back to the blood. The method is clearly effective and accurate, quick response indication, securer and safer, more tolerant, and the treatment time is short.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: March 30, 2010
    Assignee: Shanghai Jiangxia Blood Technology Co., Ltd.
    Inventors: Heping Huang, Siukwan Chang
  • Publication number: 20100076364
    Abstract: A method for batch implementation of settings in a renal replacement therapy device including: displaying on a user interface control settings which may be manually selected by an operator; selecting an independent control setting of the plurality of control settings; adjusting the independent control setting to an independent control setting level selected by an operator; temporarily storing the adjusted independent control setting level; automatically adjusting a dependent control setting level based upon the independent control level; displaying the adjusted independent control setting level and the adjusted dependent control setting, and implementing both the adjusted independent control setting level and the adjusted dependent control setting to control the device, by actuating a batch setting acceptance operation.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 25, 2010
    Applicant: CHF Solutions, Inc.
    Inventors: John J. O'Mahony, Thomas Robert Lendway, Andrew J. Halpert
  • Patent number: 7682327
    Abstract: The present invention provides a heart-lung machine which can be carried by one person and can be used independently from an external power supply, consisting of at least three modules (1, 2, 3), wherein a first module (1) contains the blood circulating elements which are necessary for the function of a heart-lung machine, a second module (2) contains a pump drive (9) and an electronic measuring equipment and a control logic (11) and a third module (3) contains the programming unit (14), whereas the second unit is separably connected to the first and the third module.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: March 23, 2010
    Assignee: Lifebridge Medizintechnik AG
    Inventor: Karsten Kirchhof
  • Patent number: 7682329
    Abstract: A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures involve filtering the separated red blood cells in a diluted state after and/or prior to flushing the filter with storage solution. Storage solution may thus be passed through the leukoreduction filter before, with and/or after the RBCs have been filtered therethrough. The red blood cell collection, filtration and storage assembly is preferably preconnected to a blood component separation disposable assembly, including, for example, a centrifuge vessel and a blood removal/return assembly for removing blood from a donor, passing the blood to the centrifuge vessel for separation of the blood into components for collection and providing for filtration of the separated red blood cell component.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: March 23, 2010
    Assignee: CaridianBCT, Inc.
    Inventors: Bruce W. Gibbs, Jon Herskovits
  • Patent number: 7682328
    Abstract: An extracorporeal blood system includes: (i) an extracorporeal blood machine; an extracorporeal blood circuit coupled operably to the machine, the extracorporeal blood circuit including first and second blood lines, the blood lines configured to be in blood flow communication with a patient; (ii) an electrical loop including first and second electrodes placed in contact with blood flowing through the extracorporeal blood circuit; (iii) a device configured to inject an electrical signal into the blood circuit via the loop; and (iv) a third electrode placed in contact with blood flowing through the extracorporeal blood circuit, the third electrode configured to enable a change in an electrical value to be measured so that an access disconnection of the extracorporeal blood circuit from the patient can be measured.
    Type: Grant
    Filed: January 16, 2006
    Date of Patent: March 23, 2010
    Assignee: Baxter International Inc.
    Inventors: James Han, Thomas P. Hartranft, Thomas D. Kelly, Angel Lasso
  • Publication number: 20100069817
    Abstract: A container (10) comprising a plurality of compartments (A, B, C) separated by compartment dividers (6), and an inlet connector (3) for receiving a liquid via a connection tube (2). The compartment dividers rupture when a sufficient pressure is applied by a liquid or gas introduced into the container (10) through the inlet connector (3). Some of the compartments comprise powder, which dissolves at the introduction of liquid into the container. A system, process and use in the field of dialysis are also disclosed.
    Type: Application
    Filed: June 15, 2007
    Publication date: March 18, 2010
    Inventors: Thore Falkvall, Per-Olov Carlsson
  • Patent number: 7674237
    Abstract: A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: March 9, 2010
    Assignee: CHF Solutions, Inc.
    Inventors: John J. O'Mahony, Mark Gelfand, Edward G. Rychlick
  • Patent number: 7666159
    Abstract: A venous reservoir in an extracorporeal blood circuit, comprising a rigid outer enclosure for a filtering mass in the form of a hollow cylinder, provided with an upper lid which comprises couplings for the inflow of blood with the portion of space delimited by the filtering mass and with a connector at the bottom, the reservoir further comprising a diaphragm which is arranged below the upper lid and is adapted to receive the blood that enters through the couplings provided in the peripheral region of the lid, at the axis of a central hole of the diaphragm there is a column with longitudinal vanes which protrude upwardly until they skim the rim of the hole and are adapted to follow the blood in its flow by gravity toward the collection region at the base of the enclosure.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: February 23, 2010
    Assignee: Eurosets S.r.l.
    Inventors: Nicola Ghelli, Edgardo Costa Maianti, Roberto Balanzoni
  • Publication number: 20100042259
    Abstract: In a method for the automatic control of blood pumps, an optimization of the blood flow is achieved by periodic speed interventions and flow changes thereby occurring, using a formed differential variable and a control algorithm. In addition, the location of possible flow resistances on the venous or arterial side can be ascertained.
    Type: Application
    Filed: February 7, 2008
    Publication date: February 18, 2010
    Inventor: Antoine P. Simons
  • Patent number: 7662110
    Abstract: Novel devices which can be used to both collect blood samples from and administer medical fluids to a patient on a repeated and continual basis using one rather than multiple needle insertions. The device typically includes a main tubing segment confluently connected to a cannula for insertion in the patient's vein. A syringe port and a volumeter for collecting blood branch separately from the main tubing segment. The device is used to collect blood by attaching an empty blood collection syringe to the syringe port, inserting the cannula in the patient's vein, allowing passive flow of blood from the main tubing segment into the volumeter under intrinsic venous blood pressure and capillary action, and then facilitating active flow of blood from the volumeter into the blood collection syringe by extending the syringe plunger. The device may be used to administer medical fluids to the patient through the main tubing segment from a medical fluid syringe or catheter attached to the syringe port.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: February 16, 2010
    Assignee: One Stick, LLC
    Inventor: Patrice Flaherty
  • Patent number: 7648476
    Abstract: A blood treatment apparatus includes a controller and a supervisor, which together monitor various sensors. The controller is equipped with a first alarm system and the supervisor is equipped with a second alarm system. To avoid competition between both alarm systems, the alarm system of the supervisor normally remains mute. A function monitoring device monitors the function of the first alarm system and signals a missing alarm to the supervisor. Only in this case will the second alarm system of the supervisor be activated.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: January 19, 2010
    Assignee: B. Braun Medizintechnologie GmbH
    Inventors: Gerhard Bock, Günter Niemetz, Sándor Dolgos, Róbert Schin
  • Patent number: 7645253
    Abstract: An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: January 12, 2010
    Assignee: National Quality Care, Inc.
    Inventors: Victor Gura, Edmond Rambod
  • Patent number: 7641626
    Abstract: The invention relates to support element (4) comprising a main body (6) having a front wall (25) and a peripheral wall (32) projecting away from the front wall. The front wall and the peripheral wall define a housing compartment (33) designed to receive a fluid distribution circuitry cooperating with a treatment unit for defining an integrated blood treatment module.
    Type: Grant
    Filed: June 6, 2007
    Date of Patent: January 5, 2010
    Assignee: Gambro Lundia AB
    Inventors: Claudio Tonelli, Vincenzo Baraldi, Massimo Zaccarelli, Annalisa Delnevo, Francesco Ribolzi, Jacques Chevallet, Jacques Duchamp, Aziz Aberkane, Gabriel Meyssonnier, Dominique Pouchoulin
  • Publication number: 20090318748
    Abstract: In blood perfusion during cardiac surgery or ventricular assistance, for treating cardiac insufficiency, use is currently made of a centrifugal pump that generates a linear flow in the circulatory system, counter to the pulsating flow generated by the heart. According to the invention, a pulsating linear flow is achieved for blood perfusion by providing, in the interior wall of the chamber or casing of the pump (3), an elastic lining (8) in the form of a bell-shaped membrane that inflates and deflates, producing variations in volume and changes in pressure that give rise to a pulsating effect in the flow at the outlet (6) from the pump (3). At the inlet (5) to the pump (3) there is a non-return valve formed by an annular thickening (11).
    Type: Application
    Filed: March 13, 2007
    Publication date: December 24, 2009
    Inventor: Salvador Mercé Vives
  • Publication number: 20090312686
    Abstract: An object of the present invention is to provide a blood purification apparatus and a priming method thereof which can firmly perform the bubble purging smoothly and in a short time during priming operation. According to the blood purification apparatus of the present invention, the tip of the arterial blood circuit can be connected to and communicated with the tip of the venous blood circuit during priming of the blood purification apparatus before dialysis, and the blood purification apparatus can perform a priming solution charging step for supplying and charging the blood circuits with priming solution under a condition in which the tip of the arterial blood circuit and the tip of the venous blood circuit are connected to and communicated with each other; and a priming solution circulating step for forcing the charged priming solution to be flowed and circulated through the blood circuits by successively changing the driving speed of the blood pump after the priming solution charging step.
    Type: Application
    Filed: June 8, 2009
    Publication date: December 17, 2009
    Applicant: Nikkiso Co., Ltd.
    Inventors: Kazuya Sakamoto, Tomohiro Furuhashi
  • Patent number: 7618542
    Abstract: A blood purifying apparatus particularly suitable for continuous blood purification, and a method of controlling the same whereby the weight of body fluid removed from a patient and a feed weight to the patient can be more accurately controlled. A blood purifying apparatus 50 adapted for the continuous blood purification includes a drain C, a dialysate feed A, and a replacement fluid feed B, which are equipped with transfer pumps 5, 6, 7, respectively, reservoir containers 8, 9, and 10, respectively, that are capable of storing a predetermined volume, and fluid level sensors 11, 12, and 13, respectively. The blood purifying apparatus further includes a single weightmeter 20 capable of measuring the reservoir containers 8, 9, and 10 all at the same time.
    Type: Grant
    Filed: August 4, 2003
    Date of Patent: November 17, 2009
    Assignee: Asahi Kasei Medical Co., Ltd.
    Inventor: Soichirou Okazaki
  • Patent number: 7615028
    Abstract: An extracorporeal blood treatment system including: a blood circuit having a first blood passage coupled at a first end to a first end of a blood treatment device and a second blood passage coupled at a first end to a second end of the treatment device, wherein the first and second blood passages each have a second end adapted to be coupled to a vascular system of a human patient; a first blood pump connectable to the first blood passage and a second blood pump connectable to the second blood passage, wherein said first and second blood pumps are adapted to move blood through the first and second blood passages in a first direction and in a reverse direction, and a pump controller operatively connected to the first and second blood pumps, said controller operates the blood pumps to cyclically move blood through the first and second blood passages in the first direction and the reverse direction.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: November 10, 2009
    Assignee: CHF Solutions Inc.
    Inventor: John J. O'Mahony