Abstract: An energy delivery system for performing myocardial revascularization on a heart of a patient including an energy pulse source that produces energy pulses sufficient to create channels in a wall of a heart, and an energy pulse delivery system connected to receive the energy pulses and deliver the energy pulses to desired locations for channels in the wall of the heart. Also disclosed are a sensor that senses a cyclical event related to the contraction and expansion of the beating heart; a controller responsive to the sensor for automatically firing the energy pulse system to provide energy to strike the beating heart only within a safe time period during a heart beat cycle; RF electrical or laser energy pulses; a temperature sensor to avoid damage caused by overheating adjacent heart tissue; a thermal conductivity cooling system; and programmably adjusting duty cycle, duration and amplitude of energy pulses.

Abstract: An eye tracking and positioning system for use with a refractive laser system includes a camera interface, a computer, and a system for moving the patient relative to the laser beam. The computer includes a video frame grabber which extracts images of the eye from the camera, and is programmed to perform an eye tracking algorithm. The eye tracking algorithm calculates the exact center of the eye pupil, and compares the center with the desired location of the laser beam, as determined by a surgeon, with an image processing algorithm. If the relative location of the eye center and the laser beam fall outside a predetermined value, the patient chair, and thereby the patient, is repositioned relative to the laser beam, as opposed to the laser beam being repositioned relative to the patient. The repositioning counters the movement of the eye.

Abstract: A laser treatment apparatus which is used to treat an affected part of a patient by irradiating a treatment laser beam to the affected part is disclosed. The apparatus includes a laser irradiation unit provided with a laser irradiation optical system for delivering the laser beam to the affected part; a contact member including a contact face which is brought into contact with at least one of the affected part and a periphery thereof; a cooler which cools down at least the contact face of the contact member; a sensor which detects at least one of a temperature of a periphery of the contact face made contact with the affected part, a temperature of a predetermined portion of at least one of the contact member and the cooler, a contact state of the contact face with respect to the affected part, and a relative substantially horizontal movement of the contact member with respect to the affected part; and an irradiation controller which controls laser irradiation based on a result of detection by the sensor.

Abstract: An apparatus for measuring an optical characteristic of an ablation standard object having a known ablation rate, as compared with an object to be processed having a unknown ablation rate which is ablated with laser beam, the apparatus comprising a retaining device for retaining the ablation standard object so that a surface thereof may be at the predetermined height, a refractive power measuring device for measuring a refractive power of the ablation standard object, which includes a projecting optical system for projecting target luminous flux for use in refractive power measurement onto the ablation standard object retained by the retaining device and a detecting optical system for detecting the target luminous flux projected by the projecting optical system, a moving device for moving the refractive power measuring device to the predetermined measuring position in order to measure the refractive power of the ablation standard object, and an output device for outputting results measured by the refractive p

Abstract: Progress of photodynamic therapy (PDT) administered over an extended period of time is monitored using an ultrasonic probe, which produces ultrasound images of an internal treatment site in real time. The ultrasound images indicate the extent and volume of an infarction zone within a tumor or other diseased tissue at the internal treatment site within a patient's body. Light is administered to the internal treatment site from either an internal or external light source that produces light in a waveband corresponding to the characteristic absorption waveband a photoreactive agent that is administered to a patient. Prior to or shortly after initiating administration of the light therapy, a baseline ultrasound image is produced for comparison to subsequent ultrasound images made after the effects of the PDT on the diseased tissue have occurred.

Abstract: A laser treatment apparatus for performing treatments on a patient's eye by irradiating a laser beam is provided with an observation optical system including eyepieces through which a patient's eye is observed, wherein the brightness of a display part for displaying setting information such as laser irradiation conditions and others is controlled based on the light reception quantity detected by a light quantity detecting device.

Abstract: A control system and method for controlling tissue ablation uses optical time domain reflectometry data to differentiate abnormal tissue from normal tissue, and to control ablation of abnormal tissue by controlling a tissue ablative apparatus. Using data provided by an interferometric apparatus, the control system provides control signals to the tissue ablative apparatus, controlling activation of the tissue ablation apparatus so that normal tissue is left untreated while abnormal tissue is ablated.

Abstract: A laser-based method and apparatus for corneal surgery. The present invention is intended to be applied primarily to ablate organic materials, and human cornea in particular. The invention uses a laser source which has the characteristics of providing a shallow ablation depth (0.2 microns or less per laser pulse), and a low ablation energy density threshold (less than or equal to about 10 mJ/cm2), to achieve optically smooth ablated corneal surfaces. The preferred laser includes a laser emitting approximately 100-50,000 laser pulses per second, with a wave-length of about 198-300 nm and a pulse duration of about 1-5,000 picoseconds. Each laser pulse is directed by a highly controllable laser scanning system. Described is a method of distributing laser pulses and the energy deposited on a target surface such that surface roughness is controlled within a specific range.

Abstract: There is disclosed a stent for implanting in the body. The stent is formed of a tube having a patterned shape which has first and second meander patterns having axes extending in first and second directions. The first meander patterns can be formed into even and odd first meander patterns. The even and odd first meander patterns are 180 out of phase with each other and the odd patterns occur between every two even patterns. The second meander patterns are intertwined with the first meander patterns. The first and second directions can be orthogonal to each other. The second meander patterns can also be formed of even and odd patterns.

Abstract: Apparatus for PNR treatment, including an elongate probe having a distal end for engaging heart tissue of a subject, and a revascularization device, which imparts energy to the heart tissue for generating perfusion-enhancing channels therein. A sensor provides an indication responsive to the treatment, preferably by receiving signals generated by the body of the subject.

Abstract: An Er:YAG laser system has a resonant cavity including an Er:YAG rod pulse-pumped by a pulsed flashlamp. The pump-pulse repetition rate and average power is selected to provide a known essentially constant thermal-lensing power in the Er:YAG rod. Design parameters of the Er:YAG rod and the resonant cavity are selected to compensate for this thermal-lensing power. A shutter in the resonant cavity, when closed or open, respectively prevents or allows a laser output-pulse to be generated in response to a pump-pulse. Laser output-pulse duration is continuously variable and is controlled by controlling the duration of flashlamp-pulses. A sequence of laser output-pulses is controlled by opening and closing the shutter. This arrangement has the advantage that the laser output-pulse repetition rate can be selected to be the flashlamp-pulse repetition rate or some sub-multiple thereof while maintaining thermal-lensing power in the rod essentially constant and compensated for.

Abstract: An apparatus for operating upon a cornea for delivering a laser beam having wavelength in an ultraviolet range emitted from a laser light source to the cornea, and for correcting ametropia by ablating the cornea with the laser beam, the apparatus comprises a correcting-hypermetropia optical system having a first aperture to restrict an ablation area, for correcting hypermetropia by changing a passing area for the laser beam, input device for inputting information necessary for defining a corneal shape after ablation, controlling device for defining an ablation shape based on the information inputted by the input device, and for driving the laser light source and the correcting-hypermetropia optical system, and a second aperture located by decentering for the center of the cornea, for transmitting the laser beam within an area of a near-point portion, whereby correction of presbyopia may be performed so that the cornea has double focal points by driving the laser light source and the correcting-hypermetropia o

Abstract: A laser system (called a UV Dermablator) and method that enables a clean, precise removal of skin while minimizing collateral damage to the skin underlying the treated region. The depth of ablation can be controlled via feedback from the physiology of the skin, namely the infusion of blood into the area of excision when skin has been ablated to a sufficient depth to produce bleeding. A second laser, such as a uv light source with a different wavelength, to penetrate the blood, heating it sufficiently to coagulate the blood. Other features provide precise control, permitting the epidermis to be removed down to the papillary dermis, following the undulations of the papillary dermis. This lateral and depth control may be accomplished by using careful observation, assisted by spectroscopic detection, to identify when the epidermis has been removed, exposing the underlying dermis, with spatial resolution appropriate for the spacing of the undulations of the papillary dermis.

Abstract: An apparatus for the photodynamic treatment of living beings or organs thereof which includes a light source, a switching device, a current source, and a computer. The light source is controllable with respect to intensity, time, wavelength, and/or spectral bands by the computer in order to obtain a predetermined spectral pattern (photon energy pattern), which is preferably a pattern sequence.

Abstract: A surgical method comprises successively orienting an ultrasound transmitter (30) to transmit ultrasound from multiple locations (65) adjacent the skin (32) surface and at each of the multiple locations (65) transmitting ultrasound (30), generating a time base, receiving ultrasound echoes, and determining from the time between transmission and reception the depth beneath the skin of tissue to be treated. The depths of the tissue (36) at the multiple locations are stored in a memory (40) associated with a programmable machine (34). The laser (50) is successively targeted on each of the multiple locations (65), and at each of the multiple locations (65) the depth of the tissue (36) to be treated beneath that location (65) is retrieved from the memory (40). The retrieved depth of the tissue (36) to be treated beneath that location determines a laser (50) excitation power that will achieve treatment of the tissue (36) at the retrieved depth. The laser (50) is excited at the determined excitation power.

Abstract: Typically, a laser emits significant energy after a control signal is generated to disable the power supply. The inherent delay between generation of a control signal for shutting off a laser power supply and actual termination of an output beam pulse in response to the control signal, is compensated in the context that the control signal is generated automatically upon coincidence of measured output beam power with a preset threshold value. Power supplied to a laser is modulated to cause generation of a pulsed laser output beam. The cumulative energy of each output beam pulse is monitored and a feedback signal indicative of measured output beam pulse energy is supplied to the power supply. The feedback signal is compared with a user-selected threshold value, and a control signal is generated for terminating the output beam pulse (by terminating input power to the laser) when the measured output pulse energy reaches the threshold value.

Abstract: To achieve highly efficient laser irradiation and well-balanced light coagulation treatment within a same treatable site by using laser beam of different wavelengths, an apparatus is disclosed which comprises a plurality of laser light sources for treatment which emit laser beams of different wavelengths, a condition setting device for determining irradiation condition of the laser light sources, a control device for controlling the laser light sources according to the settings determined at the condition setting device so as to sequentially irradiate laser beams, and a guide device for directing emitted laser beams into an eye of a patient.

Abstract: A device for removing material from a workpiece, in particular for removing a hard substance, such as tooth enamel or dentine from a tooth, or for removing ceramic materials, has a laser for irradiating the workpiece in a locally limited ablation area where material is removed, and a handling part (1) which receives the laser or is connected thereto by an optical fiber element or by a mirror arrangement. The handling part (1) is used to position the laser beam (3) in the ablation area and has a distance measurement device (11 to 15, D1, D2) to monitor the depth of material removal. While the material is being removed, the distance measurement device (11 to 15, D1, D2) measures the distance to the workpiece surface in the ablation area and therefore the depth of material removal by means of the material-removing laser or of a measurement beam (11) generated by another laser.

Abstract: A method and apparatus for the removal of, and at least inhibiting the regrowth of, unwanted hair by applying optical radiation to the follicle, including the hair shaft therein, of an energy, a duration and wavelength to enhance the optical absorption characteristics of at least some component, (i.e., melanosomes, tissue, etc.) of the follicle without appreciably damaging skin outside the follicle; and subsequently applying optical radiation to the follicle of a wavelength which is more readily absorbed by the components of the follicle having optical absorption characteristics enhanced during step (a) then by unenhanced components and of an energy and duration to heat such enhanced components sufficiently to substantially destroy the follicle.

Abstract: An apparatus for percutaneous laser revascularization of a patient's beating heart includes a laser system that produces a pulsed laser beam with a wavelength in a range of approximately 1.7 .mu.m to approximately 2.15 .mu.m, each pulse of the laser beam having a pulse duration in a range of approximately 1 ms and greater and having a pulse energy in a range of approximately 5 J to approximately 25 J. The pulse can include a train of micropulses. A fiber optic element that is coupled to the laser system is arranged with a catheter to pass through a vasculature of the patient and to deliver pulses of the laser beam to an interior wall of the patient's heart. The laser system can include a flash lamp-pumped laser in which a large capacitor bank discharges only a fraction of its stored energy through a flash lamp to fire the laser, wherein the capacitor discharge is turned off by a switchable device, such as a high current transistor, after the integrated energy of a laser pulse reaches a selected value.

Abstract: An apparatus for tissue treatment is provided, comprising a light emitter for emission of a first light beam, director for directing the first light beam towards a target area to be treated, detector for detecting at least one tissue parameter at the target area, and first light beam controller for controlling at least one parameter without interruption of the propagating light beam. The tissue parameter may be selected from the group of texture, elasticity, size and shape. The apparatus may be used for ablating a thin epidermal layer of the derma of a patient and also marks on the tissue such as marks from chloasma, liver spots, red spots, tattoos, blood vessels just below the surface, etc. as well as warts, wounds, hair follicles, etc. may be ablated or treated.

Abstract: A system for controlling a plurality of ophthalmic microsurgical instruments connected thereto. The microsurgical instruments are for use by a user such as a surgeon in performing ophthalmic surgical procedures. The system includes a data communications bus and a user interface connected to the data communications bus. The user interface provides information to the user and receives information from the user which is representative of operating parameters of the microsurgical instruments. The system also includes surgical modules connected to and controlling the microsurgical instruments as a function of at least one of the operating parameters. The surgical modules are also connected to the data communications bus. The data communications bus provides communication of data representative of the operating parameters between the user interface and the surgical modules.

Abstract: An ophthalmic operating apparatus comprising an observation optical system for observing an anterior part of patient's eye, a laser beam irradiating optical system for irradiating a laser beam for treatment on the patient's eye, a moving device for moving the laser beam irradiating optical system relatively with respect to the patient's eye, an illumination optical system for projecting an illumination light from a pupil of the patient's eye so that the anterior part being illuminated by a reflected light at a fundus of the patient's eye from a rear side, and a photographic element for photographing a retro-illumination image of the anterior part illuminated by the illumination optical system.

Abstract: Accurate, non-mechanical removal of the epithelium from essentially only the area of the cornea to be treated. In particular, an epithelium-ablative laser device irradiates the selected region of the epithelium with ablative laser energy, a spectroscopic system monitors the ablation and spectroscopically determines whether epithelium is being ablated, and a control system terminates the epithelium removal upon spectroscopic determination of a substantial absence of epithelium ablation.

Abstract: A method for maintaining the normal position of body parts includes attaching a positioning device to opposite sides of body parts abnormally approaching each other too closely. The positioning device is adjusted for repositioning the body parts to a normal position. An apparatus for maintaining the normal position of body parts includes a positioning device to be placed in the vicinity of opposite sides of body parts abnormally approaching each other too closely. The positioning device is fixed in place relative to the body parts. The positioning device is adjustable for repositioning the body parts to a normal position. The apparatus may be used in combination with body parts.

Abstract: Ophthalmologic surgical microscope which is combined internally with an optical coherence tomography ("OCT") apparatus wherein auto-focusing is provided by driving a motorized internal focusing lens of the ophthalmologic surgical microscope with a signal output from the OCT apparatus. An embodiment of the inventive ophthalmologic surgical microscope includes: (a) an optical coherence tomography ("OCT") apparatus; (b) a beamcombiner for internally coupling output from the OCT apparatus into the ophthalmologic surgical microscope; and (c) a motor for moving an internal focusing lens of the ophthalmologic surgical microscope in response to a signal from the OCT apparatus, whereby the ophthalmologic surgical microscope is auto-focused.

Abstract: An apparatus for treating a heart by stimulating revascularization of the heart or creating channels in the heart, the apparatus comprising an artificial energy source for causing a first created heartbeat and a revascularization device for creating a first revascularization event in the heart, the revascularization device being controllable to provide a first revascularization event to occur at a selected time in relation to the first created heartbeat.

Abstract: An apparatus for treating a heart by stimulating revascularization of the heart or creating channels in the heart, the apparatus comprising a sensor, an artificial energy source for causing a first created heartbeat, and a revascularization device coupled to the sensor for creating a first revascularization event in the heart, the revascularization device being controllable to cause the first revascularization event to occur at a selected time in relation to the first created heartbeat if the sensor has detected the first created heartbeat.

Abstract: An improved dental procedure and apparatus where ultraviolet radiation pulses are used to etch selectively both hard tissue and soft tissue in dental procedures. There exists distinct ablation thresholds for hard and soft tissue which are dependent on the material being ablated for a given wavelength of the ultraviolet radiation. Sufficient differences in ablation threshold exist for enamel, dentin, and carious material, thereby allowing dentists to perform both hard tissue and soft tissue procedures without excess damage to healthy enamel, dentin or other pulp structures.

Abstract: An improved dental procedure and apparatus where ultraviolet radiation pulses are used to etch selectively both hard tissue and soft tissue in dental procedures. There exists distinct ablation thresholds for hard and soft tissue which are dependent on the material being ablated for a given wavelength of the ultraviolet radiation. Sufficient differences in ablation threshold exist for enamel, dentin, and carious material, thereby allowing dentists to perform both hard tissue and soft tissue procedures without excess damage to healthy enamel, dentin or other pulp structures.

Abstract: An improved dental procedure and apparatus where ultraviolet radiation pulses are used to etch selectively both hard tissue and soft tissue in dental procedures. There exists distinct ablation thresholds for hard and soft tissue which are dependent on the material being ablated for a given wavelength of the ultraviolet radiation. Sufficient differences in ablation threshold exist for enamel, dentin, and carious material, thereby allowing dentists to perform both hard tissue and soft tissue procedures without excess damage of healthy enamel, dentin or other pulp structures.

Abstract: In order to render possible the ablation to different depths in a process for correcting the shape of a lens in which the surface of the lens is acted upon by the radiation of a pulsed radiation source through a shutter in specific regions exposed by the shutter and thereby removing material from the lens by the radiation effect during the impingement of each radiation pulse, wherein the radiation is concentrated in a bundle of rays, the cross section of which is smaller when striking the lens surface than that of the lens surface exposed by the shutter, and wherein the bundle of rays is moved such that the entire lens surface exposed by the shutter is irradiated by radiation pulses consecutively impinging on the lens surface, it is suggested that the bundle of rays is moved between successive radiation pulses only to such an extent that the regions of the lens surface struck by the radiation pulses consecutively impinging on the lens surface partially overlap.

Abstract: Methods and devices for medical treatment of biological tissue use fiber optic tips attached to the end of an optical fiber light guide for thermal treatment or photo-irradiation of said tissue, said tip including a photoluminescent material capable of acting as the tip's temperature probe. The photoluminescent material allows the tip to act as a controlled temperature surgical device or as a simple, efficient and easy to fabricate laser light diffuser.

Abstract: A hand held microsurgical instrument for applying laser energy to selected locations (sites) in an area under the skin (or other exposed translucent tissue) to provide localized photothermolysis of underlying tissue at these sites, is described. The laser energy is focused into a spot within the tissue. This spot is of sufficiently small size so that the energy density is sufficient to provide surgical or treatment effects within the tissue without damaging the surface tissue. In dermatology, for example, the technique can be used to destroy endothelial cells in blood vessels which are desired to be removed, such spider veins (nevi) in the skin, hair follicles to prevent hair growth therefrom, or other microsurgical procedures. The area is visualized while the laser beam is steered, using a deflection system, in X and Y coordinates.

Abstract: The present invention relates generally to methods and devices for detecting, destroying and removing urinary calculi and other similar structures anywhere within an animal body, and more specifically to a method for locating such structures, fragmenting and vaporizing them and related detection and control schemes.

Abstract: A combined sclerotherapy and light treatment method is described for the treatment of unwanted veins such as varicose and telangiectatic leg veins. Substantially increased success, in the range of 90-100%, has been achieved by implementing a dwell time of between 12 hours and 6 months between the light-based therapy and the sclerotherapy. Near infra-red wavelength light is preferably used in the light therapy due to its better depths of penetration through the skin to deeper lying, larger vessels such as varicose veins.

Abstract: A method for selectively ablating targeted biological material uses real-time optical feedback control to measure incandescent photoemissions emitted from irradiated biological material and, based on the measured incandescent photoemissions, adjust laser pulse parameters to selectively ablate targeted biological material. Laser pulses are directed to a target area of the subject using a delivery system. During each laser pulse, incandescent photoemissions emitted from the biological material having a wavelength of less than that of the laser pulses are measured. Based on such measured incandescent photoemissions, at least one of the wavelenght, pulse duration and energy level of each laser pulse are adjusted in order to selectively ablate targeted soft or hard biological material.

Abstract: A calibration apparatus is disclosed for measuring the properties of a laser beam. The apparatus includes a photoreactive element having a composition which reacts with laser radiation in a manner proportional to the intensity or intensity profile of the laser beam and an alignment means for disposing the photoreactive element in the path of a laser beam, such that the beam can be activate to impinge upon the photoreactive element and the properties of the beam are recorded by changes in the state of the calibration element. The calibration element may also be used to provide corrective feedback for modifying or controlling the properties of the laser beam.

Abstract: A system is provided for use with an ophthalmic treatment laser that produces a treatment laser beam. The system automatically inhibits transmission of the treatment laser beam when a threshold amount of eye movement is detected. An eye movement sensor determines measurable amounts of eye movement such as saccadic eye movement. The eye movement sensor generates light energy that is eye safe, focuses the light energy on the eye, and detects energy reflected from the eye due to the incident light energy. The eye movement sensor determines the measurable amount of eye movement based on changes in the reflected energy. A dichroic beamsplitter is optically disposed between the ophthalmic treatment laser and the eye to direct the treatment laser beam to the eye. The beamsplitter is also optically disposed between the eye movement sensor and the eye to direct the sensor's light energy to the eye and the resulting reflected energy back to the sensor.

Abstract: The present invention provides a system for communicating information from a detachable appliance to a base unit so that the base unit can calibrate its operation to match the characteristics of the detachable appliance. The invention has particular benefits when used with medical lasers. A receptacle, mounted on the laser base unit, is provided for operatively receiving a plug on the appliance and transferring energy from the base unit to the detachable appliance. To convey information about the appliance from the appliance to the base unit, an information bearing surface is mounted on the plug and is oriented substantially perpendicularly to the external surface of the plug. The information bearing surface includes a plurality of information zones which are each machine readable and optically readable by the base unit. The base unit includes components for optically detecting and decoding the information embedded in the information zones when the plug is received by the receptacle.

Abstract: A lead extraction device synchronized to the cardiac cycle which utilizes laser light to separate an implanted object, such as a pacemaker lead, from fibrous scar tissue and thereby permit the implanted object to be extracted from a body. The extraction device features a catheter having a central lumen dimensioned so a pacemaker lead will fit within. The catheter is thereby guided by the lead. The catheter has at least one optical fiber to emit laser light from the distal end and thereby separate the lead from fibrous scar tissue. A means for generating a control pulse in response to a sensed ECG signal permits the catheter to by synchronized to the cardiac cycle. In such a manner laser light may be controlled so as to avoid striking the heart at a vulnerable period in the cardiac cycle.

Abstract: The present invention involves a system for transmyocardial revascularization of a beating heart, including a laser device for ablating wall tissue of the heart being treated, with a pacemaker connected to the heart being treated, to provide electrical signals to control the cardiac cycle of that heart, and a conditioning circuit connected to both the pacemaker and to the laser, to permit the controlled "safe period" firing of the laser. The laser includes an optic waveguide articulably arranged to irradiate the wall of the heart. The conditioning circuit is programmed to permit the firing of the laser upon the time of the cardiac cycle of the heart during a non-ventricular repolarization time period.

Abstract: A method for joining or restructuring tissue consists essentially of providing a preformed film or sheet of a solid filler material which fuses to tissue upon the application of energy. The material comprises collagen, gelatin, mixtures thereof, optionally combined with a plasticizer, and the film may be cut prior to placing over the tissue. Radiofrequency energy is then applied at between about 20 and 120 Watts to the filler material and the tissue after the filler material has been placed over the tissue for about 1 to 60 seconds so that about 20 to 1800 joules are delivered to the filler material and tissue.

Abstract: A laser probe hand piece for use in laser eye surgery is disclosed having a housing fiber optic energy being fiber housed therein. The housing includes a infusion port whereby irrigating solution can be infused into the eye to cool and irrigate the surgical area, and the housing also houses an aspiration means whereby fluid and excised tissue can be aspirated from the surgical field. The laser probe hand piece and associated console employ a feedback loop cutoff whereby the laser energy is cut off if the laser is not in contact with the target tissue.

Abstract: A apparatus and method for controlling an apparatus for removing tissue from the eye performs various types of corrections using a relatively large beam, but oscillating, or dithering, that being to prevent reinforcing ridges from being formed during the tissue removal process. Further, various types of correction, such as hyperopia and astigmatism correction, are performed using a large beam that is scanned over the area to be ablated using overlapping shots. Further, the epithelium in the area to be treated is removed using an infrared fluorescent dye to dye the epithelium, and then observing the fluorescent patterns from the epithelium area to be removed. Once a certain area is no longer fluorescent after laser shots, smaller shots are then applied, selectively removing the epithelium from the remaining regions. Again, the fluorescence patterns are observed, and the process is repeated until no epithelium remains.

Abstract: A cancer diagnosis and treatment device comprising a solid-state laser generator such as an Nd-YAG laser, an alexandrite laser, or titanium sapphire laser for emitting a first laser beam having a first wavelength, a harmonic generator for generating higher harmonic laser beams of the first laser beam and outputting one of the higher harmonic laser beams, and an optical parametric oscillator for converting the harmonic laser beam outputted from the harmonic generator into second and third laser beams suitable for the cancer diagnosis and treatment, the second laser beam having a second wavelength stimulating a sterilizing photochemical reaction between the photosensitive material and the cancer foci to perform the cancer treatment and the third laser beam having a third wavelength inducing fluorescence inherent to the photosensitive material to enable the cancer diagnosis, an endoscope for guiding the second and third laser beams emitted from the laser beam source to the cancer foci and transmitting an image o

Abstract: A method and system are provided for sensing eye movement, such as saccadic eye movement, in a non-intrusive fashion. An optical delivery arrangement converts a laser beam pulse into a plurality of light spots. The light spots are focused such that they are incident on a corresponding plurality of positions located on a boundary whose movement is coincident with that of eye movement. The boundary can be defined by two visually adjoining surfaces having different coefficients of reflection. Energy is reflected from each of the positions located on the boundary receiving the light spots. An optical receiving arrangement detects the reflected energy from each of the positions. Changes in reflected energy at one or more of the positions is indicative of eye movement.

Abstract: A dermatology handpiece delivers a treatment beam of optical energy to a lesion. The handpiece has the ability to selectively determine whether or not the treatment beam is delivering optical energy to a lesion or to healthy tissue. This is achieved without visual inspection of the skin surface by the physician. Slight variations in tissue, not readily discernable by the human eye, can be detected and treated. A base line, or threshold, is established for the treatment area. Normal tissue, falling below the base line, does not receive a dose of optical energy. A threshold or base line signal is created by taking a reading of healthy skin. The dermatology handpiece is adjusted so that the treatment beam is not delivered until a threshold or base line signal is exceeded. Substantially all of a lesion receives the proper amount of optical energy in the treatment beam, while healthy tissue does not receive a dosage of optical energy.

Abstract: A high speed, high resolution, programmable laser beam modulating apparatus includes a computer connected to a high resolution micromirror array having individually addressable and movable mirrors. The computer is also connected to a pulsed laser for controlling the emission thereof. A beam homogenizing optic changes an ablating input beam from the laser into a homogeneous beam having a uniform cross-sectional energy density. The mirrors are movable between an "on" position for reflecting a portion of the homogeneous beam onto a cornea, and an "off" position for reflecting the beam away from the cornea. The computer is programmed to move the mirrors to the "on" position in a series of predetermined patterns, and the remaining mirrors to the "off" position, and to fire the laser during the presence of each pattern, so that corresponding patterns of tissue on the cornea are successively ablated therefrom.

Abstract: An ablation apparatus for ablating by laser beam including a laser beam providing means for providing laser beam to ablate an object to be processed into a desired form, a light beam delivering optical system for delivering the laser beam to the object to be processed, an ablation area changing diaphragm for changing ablation area on the object to be processed, and a control device for controlling the motion of the ablation area changing diaphragm, the ablation apparatus comprising instructing device for instructing the controlling device to form a curved surface with a first optical characteristic on the rate reference object which has a known ablation rate as to an ablation rate of the object to be processed, measuring device for measuring a second optical characteristic of the curved surface actually formed on a rate reference object in accordance with control by the controlling device, input device for inputting the second optical characteristic measured by the measuring device, and correcting device for